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- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- ABIN500425 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- ORAI3 antibody was raised against a 15 amino acid peptide from near the amino terminus of human ORAI3.
- Description
- Peptide affinity chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- N-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8°C for up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Calcium signals mediated by STIM and Orai proteins--a new paradigm in inter-organelle communication.
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function.
Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1.
Calcium signaling mechanisms in T lymphocytes.
Soboloff J, Spassova MA, Dziadek MA, Gill DL
Biochimica et biophysica acta 2006 Nov;1763(11):1161-8
Biochimica et biophysica acta 2006 Nov;1763(11):1161-8
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function.
Feske S, Gwack Y, Prakriya M, Srikanth S, Puppel SH, Tanasa B, Hogan PG, Lewis RS, Daly M, Rao A
Nature 2006 May 11;441(7090):179-85
Nature 2006 May 11;441(7090):179-85
Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1.
Mercer JC, Dehaven WI, Smyth JT, Wedel B, Boyles RR, Bird GS, Putney JW Jr
The Journal of biological chemistry 2006 Aug 25;281(34):24979-90
The Journal of biological chemistry 2006 Aug 25;281(34):24979-90
Calcium signaling mechanisms in T lymphocytes.
Lewis RS
Annual review of immunology 2001;19:497-521
Annual review of immunology 2001;19:497-521
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of ORAI3 in A20 cell lysate with AP30634PU-N at (A) 1, (B) 2 and (C) 4 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of ORAI3 in A20 cells with AP30634PU-N at 10 ?g/ml.
