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- Antigen structure
- References [9]
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- Western blot [1]
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- Product number
- 16654-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- COQ4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated COQ4 antibody (Cat. #16654-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references 4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease.
Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis.
Human COQ4 deficiency: delineating the clinical, metabolic and neuroimaging phenotypes.
The Q-junction and the inflammatory response are critical pathological and therapeutic factors in CoQ deficiency.
Resveratrol Regulates the Expression of Genes Involved in CoQ Synthesis in Liver in Mice Fed with High Fat Diet.
Characterization of human mitochondrial PDSS and COQ proteins and their roles in maintaining coenzyme Q(10) levels and each other's stability.
β-RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9(R239X) mice.
Detection of 6-demethoxyubiquinone in CoQ(10) deficiency disorders: Insights into enzyme interactions and identification of potential therapeutics.
4-Hydroxybenzoic acid restores CoQ(10) biosynthesis in human COQ2 deficiency.
Corral-Sarasa J, Martínez-Gálvez JM, González-García P, Wendling O, Jiménez-Sánchez L, López-Herrador S, Quinzii CM, Díaz-Casado ME, López LC
Cell reports 2024 May 28;43(5):114148
Cell reports 2024 May 28;43(5):114148
Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis.
Radaelli E, Assenmacher CA, Verrelle J, Banerjee E, Manero F, Khiati S, Girona A, Lopez-Lluch G, Navas P, Spinazzi M
eLife 2023 Jul 28;12
eLife 2023 Jul 28;12
Human COQ4 deficiency: delineating the clinical, metabolic and neuroimaging phenotypes.
Laugwitz L, Seibt A, Herebian D, Peralta S, Kienzle I, Buchert R, Falb R, Gauck D, Müller A, Grimmel M, Beck-Woedel S, Kern J, Daliri K, Katibeh P, Danhauser K, Leiz S, Alesi V, Baertling F, Vasco G, Steinfeld R, Wagner M, Caglayan AO, Gumus H, Burmeister M, Mayatepek E, Martinelli D, Tamhankar PM, Tamhankar V, Joset P, Steindl K, Rauch A, Bonnen PE, Froukh T, Groeschel S, Krägeloh-Mann I, Haack TB, Distelmaier F
Journal of medical genetics 2022 Sep;59(9):878-887
Journal of medical genetics 2022 Sep;59(9):878-887
The Q-junction and the inflammatory response are critical pathological and therapeutic factors in CoQ deficiency.
González-García P, Díaz-Casado ME, Hidalgo-Gutiérrez A, Jiménez-Sánchez L, Bakkali M, Barriocanal-Casado E, Escames G, Chiozzi RZ, Völlmy F, Zaal EA, Berkers CR, Heck AJR, López LC
Redox biology 2022 Sep;55:102403
Redox biology 2022 Sep;55:102403
Resveratrol Regulates the Expression of Genes Involved in CoQ Synthesis in Liver in Mice Fed with High Fat Diet.
Meza-Torres C, Hernández-Camacho JD, Cortés-Rodríguez AB, Fang L, Bui Thanh T, Rodríguez-Bies E, Navas P, López-Lluch G
Antioxidants (Basel, Switzerland) 2020 May 15;9(5)
Antioxidants (Basel, Switzerland) 2020 May 15;9(5)
Characterization of human mitochondrial PDSS and COQ proteins and their roles in maintaining coenzyme Q(10) levels and each other's stability.
Yen HC, Yeh WY, Lee SH, Feng YH, Yang SL
Biochimica et biophysica acta. Bioenergetics 2020 Jul 1;1861(7):148192
Biochimica et biophysica acta. Bioenergetics 2020 Jul 1;1861(7):148192
β-RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9(R239X) mice.
Hidalgo-Gutiérrez A, Barriocanal-Casado E, Bakkali M, Díaz-Casado ME, Sánchez-Maldonado L, Romero M, Sayed RK, Prehn C, Escames G, Duarte J, Acuña-Castroviejo D, López LC
EMBO molecular medicine 2019 Jan;11(1)
EMBO molecular medicine 2019 Jan;11(1)
Detection of 6-demethoxyubiquinone in CoQ(10) deficiency disorders: Insights into enzyme interactions and identification of potential therapeutics.
Herebian D, Seibt A, Smits SHJ, Bünning G, Freyer C, Prokisch H, Karall D, Wredenberg A, Wedell A, López LC, Mayatepek E, Distelmaier F
Molecular genetics and metabolism 2017 Jul;121(3):216-223
Molecular genetics and metabolism 2017 Jul;121(3):216-223
4-Hydroxybenzoic acid restores CoQ(10) biosynthesis in human COQ2 deficiency.
Herebian D, Seibt A, Smits SHJ, Rodenburg RJ, Mayatepek E, Distelmaier F
Annals of clinical and translational neurology 2017 Dec;4(12):902-908
Annals of clinical and translational neurology 2017 Dec;4(12):902-908
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The COQ4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human COQ4. This antibody recognizes human,mouse,rat antigen. The COQ4 antibody has been validated for the following applications: ELISA, WB analysis.
