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- Antigen structure
- References [20]
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- Product number
- 10286-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10286-1-AP, RRID:AB_10667460
- Product name
- uPAR antibody
- Antibody type
- Polyclonal
- Description
- uPAR antibody (Cat. #10286-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A transient transcriptional activation governs unpolarized-to-polarized morphogenesis during embryo implantation.
Plasminogen activator urokinase interacts with the fusion protein and antagonizes the growth of Peste des petits ruminants virus.
ICAM-1-suPAR-CD11b Axis Is a Novel Therapeutic Target for Metastatic Triple-Negative Breast Cancer.
γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.
YY1 regulates the proliferation and invasion of triple-negative breast cancer via activating PLAUR.
Endocytosis of Peptidase Inhibitor SerpinE2 promotes Myocardial Fibrosis through activating ERK1/2 and β-catenin Signaling Pathways.
Baohuoside I Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer.
A Dual-Reporter Platform for Screening Tumor-Targeted Extracellular Vesicles.
PLAUR as a Potential Biomarker Associated with Immune Infiltration in Bladder Urothelial Carcinoma.
Staphylococcus aureus on the effect of expression of MMPs/TIMPs and uPA system in bovine mammary fibroblasts.
CLEC14A protects against podocyte injury in mice with adriamycin nephropathy.
Identification of an immune-related signature indicating the dedifferentiation of thyroid cells.
The Plasma Soluble Urokinase Plasminogen Activator Receptor Is Related to Disease Activity of Patients with ANCA-Associated Vasculitis.
Forkhead Box Q1 Is Critical to Angiogenesis and Macrophage Recruitment of Colorectal Cancer.
Ulinastatin Inhibits Osteoclastogenesis and Suppresses Ovariectomy-Induced Bone Loss by Downregulating uPAR.
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
High-Purity Magnesium Staples Suppress Inflammatory Response in Rectal Anastomoses.
Ligand binding alters dimerization and sequestering of urokinase receptors in raft-mimicking lipid mixtures.
Regulation of u-PAR gene expression by H2A.Z is modulated by the MEK-ERK/AP-1 pathway.
Lyu X, Cui Y, Kong Y, Yang M, Shen H, Liao S, Li S, An C, Wang H, Zhang Z, Ong J, Li Y, Du P
Molecular cell 2024 Jul 25;84(14):2665-2681.e13
Molecular cell 2024 Jul 25;84(14):2665-2681.e13
Plasminogen activator urokinase interacts with the fusion protein and antagonizes the growth of Peste des petits ruminants virus.
Wu J, Yang W, Li L, Wu J, He J, Ru Y, Ren J, Wang Y, Zheng H, Shang Y, Li D
Journal of virology 2024 Apr 16;98(4):e0014624
Journal of virology 2024 Apr 16;98(4):e0014624
ICAM-1-suPAR-CD11b Axis Is a Novel Therapeutic Target for Metastatic Triple-Negative Breast Cancer.
Li D, Hemati H, Park Y, Taftaf R, Zhang Y, Liu J, Cristofanilli M, Liu X
Cancers 2023 May 12;15(10)
Cancers 2023 May 12;15(10)
γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.
Chen W, Yu H, Sun C, Dong M, Zhao N, Wang Y, Yu K, Zhang J, Xu N, Liu W
Toxicology letters 2023 Jul 1;383:177-191
Toxicology letters 2023 Jul 1;383:177-191
YY1 regulates the proliferation and invasion of triple-negative breast cancer via activating PLAUR.
Zhang C, Chen S, Wang W, Gao Y
Functional & integrative genomics 2023 Aug 8;23(3):269
Functional & integrative genomics 2023 Aug 8;23(3):269
Endocytosis of Peptidase Inhibitor SerpinE2 promotes Myocardial Fibrosis through activating ERK1/2 and β-catenin Signaling Pathways.
Li C, Lv LF, Qi-Li MG, Yang R, Wang YJ, Chen SS, Zhang MX, Li TY, Yu T, Zhou YH, Liang HH, Shan HL, Li XL
International journal of biological sciences 2022;18(16):6008-6019
International journal of biological sciences 2022;18(16):6008-6019
Baohuoside I Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Ma M, Fan AY, Liu Z, Yang LQ, Huang JM, Pang ZY, Yin F
Frontiers in pharmacology 2022;13:874952
Frontiers in pharmacology 2022;13:874952
Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer.
Sela Y, Li J, Maheswaran S, Norgard R, Yuan S, Hubbi M, Doepner M, Xu JP, Ho ES, Mesaros C, Sheehan C, Croley G, Muir A, Blair IA, Shalem O, Dang CV, Stanger BZ
Cancer research 2022 May 16;82(10):1890-1908
Cancer research 2022 May 16;82(10):1890-1908
A Dual-Reporter Platform for Screening Tumor-Targeted Extracellular Vesicles.
Kanada M, Linenfelser L, Cox E, Gilad AA
Pharmaceutics 2022 Feb 22;14(3)
Pharmaceutics 2022 Feb 22;14(3)
PLAUR as a Potential Biomarker Associated with Immune Infiltration in Bladder Urothelial Carcinoma.
Liu M, Chen S, Zhang A, Zheng Q, Fu J
Journal of inflammation research 2021;14:4629-4641
Journal of inflammation research 2021;14:4629-4641
Staphylococcus aureus on the effect of expression of MMPs/TIMPs and uPA system in bovine mammary fibroblasts.
Miao Z, Ding Y, Bi Y, Chen M, Cao X, Wang F
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2021 Jun;54(3):411-419
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2021 Jun;54(3):411-419
CLEC14A protects against podocyte injury in mice with adriamycin nephropathy.
Su Z, Li Y, Lv H, Cui X, Liu M, Wang Z, Zhang Y, Zhen J, Tang W, Wang X, Yi F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jul;35(7):e21711
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jul;35(7):e21711
Identification of an immune-related signature indicating the dedifferentiation of thyroid cells.
Wang X, Peng W, Li C, Qin R, Zhong Z, Sun C
Cancer cell international 2021 Apr 23;21(1):231
Cancer cell international 2021 Apr 23;21(1):231
The Plasma Soluble Urokinase Plasminogen Activator Receptor Is Related to Disease Activity of Patients with ANCA-Associated Vasculitis.
Huang F, Li Y, Xu R, Cheng A, Lv Y, Liu Q
Mediators of inflammation 2020;2020:7850179
Mediators of inflammation 2020;2020:7850179
Forkhead Box Q1 Is Critical to Angiogenesis and Macrophage Recruitment of Colorectal Cancer.
Tang H, Zheng J, Bai X, Yue KL, Liang JH, Li DY, Wang LP, Wang JL, Guo Q
Frontiers in oncology 2020;10:564298
Frontiers in oncology 2020;10:564298
Ulinastatin Inhibits Osteoclastogenesis and Suppresses Ovariectomy-Induced Bone Loss by Downregulating uPAR.
Huang JM, Ren RY, Bao Y, Guo JC, Xiang W, Jing XZ, Shi J, Zhang GX, Li L, Tian Y, Kang H, Guo FJ
Frontiers in pharmacology 2018;9:1016
Frontiers in pharmacology 2018;9:1016
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
Liu M, Liang K, Zhen J, Zhou M, Wang X, Wang Z, Wei X, Zhang Y, Sun Y, Zhou Z, Su H, Zhang C, Li N, Gao C, Peng J, Yi F
Nature communications 2017 Sep 4;8(1):413
Nature communications 2017 Sep 4;8(1):413
High-Purity Magnesium Staples Suppress Inflammatory Response in Rectal Anastomoses.
Xia J, Chen H, Yan J, Wu H, Wang H, Guo J, Zhang X, Zhang S, Zhao C, Chen Y
ACS applied materials & interfaces 2017 Mar 22;9(11):9506-9515
ACS applied materials & interfaces 2017 Mar 22;9(11):9506-9515
Ligand binding alters dimerization and sequestering of urokinase receptors in raft-mimicking lipid mixtures.
Ge Y, Siegel AP, Jordan R, Naumann CA
Biophysical journal 2014 Nov 4;107(9):2101-11
Biophysical journal 2014 Nov 4;107(9):2101-11
Regulation of u-PAR gene expression by H2A.Z is modulated by the MEK-ERK/AP-1 pathway.
Chauhan S, Boyd DD
Nucleic acids research 2012 Jan;40(2):600-13
Nucleic acids research 2012 Jan;40(2):600-13
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The uPAR antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human uPAR. This antibody recognizes human, mouse antigen. The uPAR antibody has been validated for the following applications: ELISA, WB analysis.
