Antibody data

Product number
17-3879-42 - Provider product page
Provider
Invitrogen Antibodies
Product name
CD87 (UPAR) Monoclonal Antibody (VIM5), APC, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: This VIM5 monoclonal antibody reacts with human CD87, a GPI-linked receptor for urokinase plasminogen activator (uPA). By sequestering uPA, CD87 is involved in the conversion of plasminogen to plasmin on the leading edge of migrating cells, a process critical for chemotaxis. CD87 is expressed on the surface of monocytes, dendritic cells, and on activated T and NK cells. Interestingly, in granulocytes, CD87 expressed in the cytoplasm and on the cell surface. Non-hematopoietic cells such as endothelial cells, keratinocytes, and fibroblasts, also express this receptor. Finally, CD87 plays a role in cell adhesion and migration, angiogenesis, and tumor metastasis. This monoclonal antibody has been reported to have neutralization activity. Applications Reported: This VIM5 antibody has been reported for use in flow cytometric analysis. Applications Tested: This VIM5 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.5 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
VIM5
Vial size
100 Tests
Concentration
5 µL/Test
Storage
4° C, store in dark, DO NOT FREEZE!
PLAUR protein structure - 17-3879-42 shown in red.