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- Antibody Data
- Antigen structure
- References [29]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 11990-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11990-1-AP, RRID:AB_2180758
- Product name
- RPS3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RPS3 antibody (Cat. #11990-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The coordinated action of UFMylation and the RQC pathways clears arrested polypeptides at the ER.
Uridine metabolism promotes lung adenocarcinoma progression by activating FBL transcription via YBX1.
YTHDF proteins and m(6)A-RNA clients undergo autophagic turnover during contact inhibition.
m(6)A Reader hnRNPA2B1 Modulates Late Pachytene Progression in Male Meiosis Through Post-Transcriptional Control.
HuB serves as the central hub for connecting HuR-related mRNAs with translation machinery in inflammation.
Proteomic profiling of primary cilia in the developing brain uncovers new regulators of cortical development.
A methyltransferase-independent role for METTL1 in tRNA aminoacylation and oncogenic transformation.
DDX41 resolves G-quadruplexes to maintain erythroid genome integrity and prevent cGAS-mediated cell death.
DDX41 dissolves G-quadruplexes to maintain erythroid genome integrity and prevent cGAS-mediated cell death.
PELI1: key players in the oncogenic characteristics of pancreatic Cancer.
Ccr4-not ubiquitin ligase signaling regulates ribosomal protein homeostasis and inhibits 40S ribosomal autophagy.
Nonstructural protein 1 widespread RNA decay phenotype varies among coronaviruses.
Kaposi's sarcoma-associated herpesvirus induces specialised ribosomes to efficiently translate viral lytic mRNAs.
RPS3 Promotes the Metastasis and Cisplatin Resistance of Adenoid Cystic Carcinoma.
MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes.
Glyphosate exposure deteriorates oocyte meiotic maturation via induction of organelle dysfunctions in pigs.
The N-terminal domain of SARS-CoV-2 nsp1 plays key roles in suppression of cellular gene expression and preservation of viral gene expression.
Cilia locally synthesize proteins to sustain their ultrastructure and functions.
Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN).
Interactome of the Autoimmune Risk Protein ANKRD55.
SseL Deubiquitinates RPS3 to Inhibit Its Nuclear Translocation.
Hsp90 Interacts with the Bacterial Effector NleH1.
RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice.
Escherichia coli virulence protein NleH1 interaction with the v-Crk sarcoma virus CT10 oncogene-like protein (CRKL) governs NleH1 inhibition of the ribosomal protein S3 (RPS3)/nuclear factor κB (NF-κB) pathway.
Functional differences and interactions between the Escherichia coli type III secretion system effectors NleH1 and NleH2.
Mice with null mutation of Ceacam I develop nonalcoholic steatohepatitis.
Ribosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domain.
DNA repair efficiency in transgenic mice over expressing ribosomal protein S3.
Knockdown of ribosomal protein S3 protects human cells from genotoxic stress.
Mihailovic M, Anisimova AS, Erte B, Zhan N, Styliara I, Dagdas Y, Karagöz GE
The EMBO journal 2026 May;45(9):3252-3275
The EMBO journal 2026 May;45(9):3252-3275
Uridine metabolism promotes lung adenocarcinoma progression by activating FBL transcription via YBX1.
Wang X, Chen L, Li Y, Chen L, Hao C, Yan Q, Yu S, Zhang C, Li R, Xu B, Yao Y, Song Q
Journal of translational medicine 2026 Apr 15;24(1)
Journal of translational medicine 2026 Apr 15;24(1)
YTHDF proteins and m(6)A-RNA clients undergo autophagic turnover during contact inhibition.
Ho-Xuan H, Bruckmann A, Natali L, Prieto-Garcia C, Stuke JFM, Brunello L, Vicente A, Pfab A, Wesseling H, Cano-Franco S, Khatri A, Larivera S, Sanz-Martinez P, de la Cruz-Thea B, Jacomin AC, Prochazka J, Feederle R, Dötsch V, Sedlacek R, Hummer G, Kaiser S, Dikic I, Musri MM, Meister G, Stolz A
Cell reports 2025 Sep 23;44(9):116188
Cell reports 2025 Sep 23;44(9):116188
m(6)A Reader hnRNPA2B1 Modulates Late Pachytene Progression in Male Meiosis Through Post-Transcriptional Control.
Yin L, Zhang Y, Zhang B, Zhang J, Xiong M, Jiang N, Xiao J, Gao H, Xiong W, Wang X, Wang F, Yuan S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e06600
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e06600
HuB serves as the central hub for connecting HuR-related mRNAs with translation machinery in inflammation.
Zhang J, Huang X, Tang Y, Zhong X, Wang J, Wei M, Han X, Ke Y, Ba X
Communications biology 2025 Nov 30;9(1):3
Communications biology 2025 Nov 30;9(1):3
Proteomic profiling of primary cilia in the developing brain uncovers new regulators of cortical development.
Liu X, Gutierrez OT, Kaur G, Al-Issa Y, Baboo S, Diedrich JK, Cai E, Yates JR 3rd, Ge X
bioRxiv : the preprint server for biology 2025 May 4;
bioRxiv : the preprint server for biology 2025 May 4;
A methyltransferase-independent role for METTL1 in tRNA aminoacylation and oncogenic transformation.
Ali RH, Orellana EA, Lee SH, Chae YC, Chen Y, Clauwaert J, Kennedy AL, Gutierrez AE, Papke DJ, Valenzuela M, Silverman B, Falzetta A, Ficarro SB, Marto JA, Fletcher CDM, Perez-Atayde A, Alcindor T, Shimamura A, Prensner JR, Gregory RI, Gutierrez A
Molecular cell 2025 Mar 6;85(5):948-961.e11
Molecular cell 2025 Mar 6;85(5):948-961.e11
DDX41 resolves G-quadruplexes to maintain erythroid genome integrity and prevent cGAS-mediated cell death.
Bi H, Ren K, Wang P, Li E, Han X, Wang W, Yang J, Aydemir I, Tao K, Ma R, Godley LA, Liu Y, Shukla V, Bartom ET, Tang Y, Blanc L, Sukhanova M, Ji P
Nature communications 2025 Aug 5;16(1):7195
Nature communications 2025 Aug 5;16(1):7195
DDX41 dissolves G-quadruplexes to maintain erythroid genome integrity and prevent cGAS-mediated cell death.
Bi H, Ren K, Wang P, Li E, Han X, Wang W, Yang J, Aydemir I, Tao K, Godley L, Liu Y, Shukla V, Bartom ET, Tang Y, Blanc L, Sukhanova M, Ji P
bioRxiv : the preprint server for biology 2024 Oct 17;
bioRxiv : the preprint server for biology 2024 Oct 17;
PELI1: key players in the oncogenic characteristics of pancreatic Cancer.
Fei X, Zhu C, Liu P, Liu S, Ren L, Lu R, Hou J, Gao Y, Wang X, Pan Y
Journal of experimental & clinical cancer research : CR 2024 Mar 25;43(1):91
Journal of experimental & clinical cancer research : CR 2024 Mar 25;43(1):91
Ccr4-not ubiquitin ligase signaling regulates ribosomal protein homeostasis and inhibits 40S ribosomal autophagy.
Johnson DL, Kumar R, Kakhniashvili D, Pfeffer LM, Laribee RN
The Journal of biological chemistry 2024 Aug;300(8):107582
The Journal of biological chemistry 2024 Aug;300(8):107582
Nonstructural protein 1 widespread RNA decay phenotype varies among coronaviruses.
Bermudez Y, Miles J, Muller M
iScience 2023 Jan 20;26(1):105887
iScience 2023 Jan 20;26(1):105887
Kaposi's sarcoma-associated herpesvirus induces specialised ribosomes to efficiently translate viral lytic mRNAs.
Murphy JC, Harrington EM, Schumann S, Vasconcelos EJR, Mottram TJ, Harper KL, Aspden JL, Whitehouse A
Nature communications 2023 Jan 18;14(1):300
Nature communications 2023 Jan 18;14(1):300
RPS3 Promotes the Metastasis and Cisplatin Resistance of Adenoid Cystic Carcinoma.
Rui X, Huang Z, Chen R, Chen Y, Wang Y, Huang Z
Frontiers in oncology 2022;12:804439
Frontiers in oncology 2022;12:804439
MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes.
Ding DX, Wang Y, Yan W, Fu WN
iScience 2022 Mar 18;25(3):103955
iScience 2022 Mar 18;25(3):103955
Glyphosate exposure deteriorates oocyte meiotic maturation via induction of organelle dysfunctions in pigs.
Xing C, Chen S, Wang Y, Pan Z, Zou Y, Sun S, Ren Z, Zhang Y
Journal of animal science and biotechnology 2022 Jul 8;13(1):80
Journal of animal science and biotechnology 2022 Jul 8;13(1):80
The N-terminal domain of SARS-CoV-2 nsp1 plays key roles in suppression of cellular gene expression and preservation of viral gene expression.
Mendez AS, Ly M, González-Sánchez AM, Hartenian E, Ingolia NT, Cate JH, Glaunsinger BA
Cell reports 2021 Oct 19;37(3):109841
Cell reports 2021 Oct 19;37(3):109841
Cilia locally synthesize proteins to sustain their ultrastructure and functions.
Hao K, Chen Y, Yan X, Zhu X
Nature communications 2021 Nov 30;12(1):6971
Nature communications 2021 Nov 30;12(1):6971
Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN).
Duan TL, Jiao H, He GJ, Yan YB
Cells 2020 Jan 9;9(1)
Cells 2020 Jan 9;9(1)
Interactome of the Autoimmune Risk Protein ANKRD55.
Ugidos N, Mena J, Baquero S, Alloza I, Azkargorta M, Elortza F, Vandenbroeck K
Frontiers in immunology 2019;10:2067
Frontiers in immunology 2019;10:2067
SseL Deubiquitinates RPS3 to Inhibit Its Nuclear Translocation.
Wu M, El Qaidi S, Hardwidge PR
Pathogens (Basel, Switzerland) 2018 Nov 7;7(4)
Pathogens (Basel, Switzerland) 2018 Nov 7;7(4)
Hsp90 Interacts with the Bacterial Effector NleH1.
Wu M, Hardwidge PR
Pathogens (Basel, Switzerland) 2018 Nov 13;7(4)
Pathogens (Basel, Switzerland) 2018 Nov 13;7(4)
RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice.
Jiang L, Li T, Zhang X, Zhang B, Yu C, Li Y, Fan S, Jiang X, Khan T, Hao Q, Xu P, Nadano D, Huleihel M, Lunenfeld E, Wang PJ, Zhang Y, Shi Q
Current biology : CB 2017 May 22;27(10):1498-1505.e6
Current biology : CB 2017 May 22;27(10):1498-1505.e6
Escherichia coli virulence protein NleH1 interaction with the v-Crk sarcoma virus CT10 oncogene-like protein (CRKL) governs NleH1 inhibition of the ribosomal protein S3 (RPS3)/nuclear factor κB (NF-κB) pathway.
Pham TH, Gao X, Singh G, Hardwidge PR
The Journal of biological chemistry 2013 Nov 29;288(48):34567-74
The Journal of biological chemistry 2013 Nov 29;288(48):34567-74
Functional differences and interactions between the Escherichia coli type III secretion system effectors NleH1 and NleH2.
Pham TH, Gao X, Tsai K, Olsen R, Wan F, Hardwidge PR
Infection and immunity 2012 Jun;80(6):2133-40
Infection and immunity 2012 Jun;80(6):2133-40
Mice with null mutation of Ceacam I develop nonalcoholic steatohepatitis.
Ghosh S, Kaw M, Patel PR, Ledford KJ, Bowman TA, McInerney MF, Erickson SK, Bourey RE, Najjar SM
Hepatic medicine : evidence and research 2010 May;2010(2):69-78
Hepatic medicine : evidence and research 2010 May;2010(2):69-78
Ribosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domain.
Yadavilli S, Mayo LD, Higgins M, Lain S, Hegde V, Deutsch WA
DNA repair 2009 Oct 2;8(10):1215-24
DNA repair 2009 Oct 2;8(10):1215-24
DNA repair efficiency in transgenic mice over expressing ribosomal protein S3.
Hegde V, Yadavilli S, McLaughlin LD, Deutsch WA
Mutation research 2009 Jun 18;666(1-2):16-22
Mutation research 2009 Jun 18;666(1-2):16-22
Knockdown of ribosomal protein S3 protects human cells from genotoxic stress.
Hegde V, Yadavilli S, Deutsch WA
DNA repair 2007 Jan 4;6(1):94-9
DNA repair 2007 Jan 4;6(1):94-9
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 11990-1-AP(RPS3 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RPS3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RPS3. This antibody recognizes human, mouse antigen. The RPS3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
