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Protein structure
ATP6AP1
ATPase H+ transporting accessory protein 116A, Ac45, ATP6IP1, ATP6S1, CF2, ORF, VATPS1, XAP-3, XAP3
This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013]
Top validated antibodies |
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| Novus Biologicals |  H00000537-M01 |
2 references | Monoclonal |
WB
EL
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| antibodies-online | ABIN560008 |
1 references | Monoclonal |
WB
EL
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| Abnova Corporation | H00000537-M01 |
1 references | Monoclonal |
WB
EL
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| Invitrogen Antibodies | PA5-102388 |
Polyclonal |
WB
ICC
IHC
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| Proteintech Group | 15305-1-AP |
Polyclonal |
WB
EL
IHC
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