ABIN362322
antibody from antibodies-online
Targeting: MAPT
DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau
Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362322 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Microtubule-Associated Protein tau (MAPT) (pThr212) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pThr212 (S-R-T (p) -P-S) derived from Human Tau. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pThr212
- Isotype
- IgG
- Vial size
- 100 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Dysregulation of protein phosphorylation/dephosphorylation in Alzheimer's disease: a therapeutic target.
Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation.
Gong CX, Liu F, Grundke-Iqbal I, Iqbal K
Journal of biomedicine & biotechnology 2006;2006(3):31825
Journal of biomedicine & biotechnology 2006;2006(3):31825
Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation.
Zheng-Fischhöfer Q, Biernat J, Mandelkow EM, Illenberger S, Godemann R, Mandelkow E
European journal of biochemistry / FEBS 1998 Mar 15;252(3):542-52
European journal of biochemistry / FEBS 1998 Mar 15;252(3):542-52
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