ABIN362073
antibody from antibodies-online
Targeting: MAPT
DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau
Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362073 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN362073, RRID:AB_10953882
- Product name
- anti-Microtubule-Associated Protein tau (MAPT) (pThr205) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pThr205 (P-G-T (p) -P-G) derived from Human Tau. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pThr205
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Synaptic released zinc promotes tau hyperphosphorylation by inhibition of protein phosphatase 2A (PP2A).
Neuroglobin attenuates Alzheimer-like tau hyperphosphorylation by activating Akt signaling.
Tau hyperphosphorylation is associated with memory impairment after exposure to 1.5% isoflurane without temperature maintenance in rats.
Protective effects of lithium treatment for spatial memory deficits induced by tau hyperphosphorylation in splenectomized rats.
Promotion of hyperphosphorylation by frontotemporal dementia tau mutations.
Casein kinase 1 delta phosphorylates tau and disrupts its binding to microtubules.
The environmental toxin arsenite induces tau hyperphosphorylation.
Phosphorylation of tau is regulated by PKN.
Sun XY, Wei YP, Xiong Y, Wang XC, Xie AJ, Wang XL, Yang Y, Wang Q, Lu YM, Liu R, Wang JZ
The Journal of biological chemistry 2012 Mar 30;287(14):11174-82
The Journal of biological chemistry 2012 Mar 30;287(14):11174-82
Neuroglobin attenuates Alzheimer-like tau hyperphosphorylation by activating Akt signaling.
Chen LM, Xiong YS, Kong FL, Qu M, Wang Q, Chen XQ, Wang JZ, Zhu LQ
Journal of neurochemistry 2012 Jan;120(1):157-64
Journal of neurochemistry 2012 Jan;120(1):157-64
Tau hyperphosphorylation is associated with memory impairment after exposure to 1.5% isoflurane without temperature maintenance in rats.
Tan W, Cao X, Wang J, Lv H, Wu B, Ma H
European journal of anaesthesiology 2010 Sep;27(9):835-41
European journal of anaesthesiology 2010 Sep;27(9):835-41
Protective effects of lithium treatment for spatial memory deficits induced by tau hyperphosphorylation in splenectomized rats.
Tan WF, Cao XZ, Wang JK, Lv HW, Wu BY, Ma H
Clinical and experimental pharmacology & physiology 2010 Oct;37(10):1010-5
Clinical and experimental pharmacology & physiology 2010 Oct;37(10):1010-5
Promotion of hyperphosphorylation by frontotemporal dementia tau mutations.
Alonso Adel C, Mederlyova A, Novak M, Grundke-Iqbal I, Iqbal K
The Journal of biological chemistry 2004 Aug 13;279(33):34873-81
The Journal of biological chemistry 2004 Aug 13;279(33):34873-81
Casein kinase 1 delta phosphorylates tau and disrupts its binding to microtubules.
Li G, Yin H, Kuret J
The Journal of biological chemistry 2004 Apr 16;279(16):15938-45
The Journal of biological chemistry 2004 Apr 16;279(16):15938-45
The environmental toxin arsenite induces tau hyperphosphorylation.
Giasson BI, Sampathu DM, Wilson CA, Vogelsberg-Ragaglia V, Mushynski WE, Lee VM
Biochemistry 2002 Dec 24;41(51):15376-87
Biochemistry 2002 Dec 24;41(51):15376-87
Phosphorylation of tau is regulated by PKN.
Taniguchi T, Kawamata T, Mukai H, Hasegawa H, Isagawa T, Yasuda M, Hashimoto T, Terashima A, Nakai M, Mori H, Ono Y, Tanaka C
The Journal of biological chemistry 2001 Mar 30;276(13):10025-31
The Journal of biological chemistry 2001 Mar 30;276(13):10025-31
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