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LearnABIN362077
antibody from antibodies-online
Targeting: MAPT
DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362077 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN362077, RRID:AB_10954599
- Product name
- anti-Microtubule-Associated Protein tau (MAPT) (pThr231) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pThr231 (V-R-T (p) -P-P) derived from Human Tau. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pThr231
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Synaptic released zinc promotes tau hyperphosphorylation by inhibition of protein phosphatase 2A (PP2A).
Neuroglobin attenuates Alzheimer-like tau hyperphosphorylation by activating Akt signaling.
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation.
1H NMR study on the binding of Pin1 Trp-Trp domain with phosphothreonine peptides.
Tau mutations in frontotemporal dementia FTDP-17 and their relevance for Alzheimer's disease.
Characterization of in vitro glycation sites of tau.
Sun XY, Wei YP, Xiong Y, Wang XC, Xie AJ, Wang XL, Yang Y, Wang Q, Lu YM, Liu R, Wang JZ
The Journal of biological chemistry 2012 Mar 30;287(14):11174-82
The Journal of biological chemistry 2012 Mar 30;287(14):11174-82
Neuroglobin attenuates Alzheimer-like tau hyperphosphorylation by activating Akt signaling.
Chen LM, Xiong YS, Kong FL, Qu M, Wang Q, Chen XQ, Wang JZ, Zhu LQ
Journal of neurochemistry 2012 Jan;120(1):157-64
Journal of neurochemistry 2012 Jan;120(1):157-64
Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation.
Babu JR, Geetha T, Wooten MW
Journal of neurochemistry 2005 Jul;94(1):192-203
Journal of neurochemistry 2005 Jul;94(1):192-203
1H NMR study on the binding of Pin1 Trp-Trp domain with phosphothreonine peptides.
Wintjens R, Wieruszeski JM, Drobecq H, Rousselot-Pailley P, Buée L, Lippens G, Landrieu I
The Journal of biological chemistry 2001 Jul 6;276(27):25150-6
The Journal of biological chemistry 2001 Jul 6;276(27):25150-6
Tau mutations in frontotemporal dementia FTDP-17 and their relevance for Alzheimer's disease.
Goedert M, Spillantini MG
Biochimica et biophysica acta 2000 Jul 26;1502(1):110-21
Biochimica et biophysica acta 2000 Jul 26;1502(1):110-21
Characterization of in vitro glycation sites of tau.
Nacharaju P, Ko L, Yen SH
Journal of neurochemistry 1997 Oct;69(4):1709-19
Journal of neurochemistry 1997 Oct;69(4):1709-19
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