ABIN362082
antibody from antibodies-online
Targeting: MAPT
DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau
Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362082 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Microtubule-Associated Protein tau (MAPT) (pSer404) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pSer404 (D-T-S (p) -P-R) derived from Human Tau. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pSer404
- Isotype
- IgG
- Vial size
- 100 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Casein kinase 1 delta phosphorylates tau and disrupts its binding to microtubules.
Cdk5 is a key factor in tau aggregation and tangle formation in vivo.
The environmental toxin arsenite induces tau hyperphosphorylation.
The microtubule binding domain of tau protein.
Li G, Yin H, Kuret J
The Journal of biological chemistry 2004 Apr 16;279(16):15938-45
The Journal of biological chemistry 2004 Apr 16;279(16):15938-45
Cdk5 is a key factor in tau aggregation and tangle formation in vivo.
Noble W, Olm V, Takata K, Casey E, Mary O, Meyerson J, Gaynor K, LaFrancois J, Wang L, Kondo T, Davies P, Burns M, Veeranna, Nixon R, Dickson D, Matsuoka Y, Ahlijanian M, Lau LF, Duff K
Neuron 2003 May 22;38(4):555-65
Neuron 2003 May 22;38(4):555-65
The environmental toxin arsenite induces tau hyperphosphorylation.
Giasson BI, Sampathu DM, Wilson CA, Vogelsberg-Ragaglia V, Mushynski WE, Lee VM
Biochemistry 2002 Dec 24;41(51):15376-87
Biochemistry 2002 Dec 24;41(51):15376-87
The microtubule binding domain of tau protein.
Lee G, Neve RL, Kosik KS
Neuron 1989 Jun;2(6):1615-24
Neuron 1989 Jun;2(6):1615-24
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