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LearnABIN196811
antibody from antibodies-online
Targeting: MAPT
DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN196811 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Microtubule-Associated Protein tau (MAPT) (pSer404) antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide around phosphorylation site of Serine 404 (D-T-Sp-P-R) derived from Human Tau.
- Description
- Affinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pSer404
- Vial size
- 50 μL
- Concentration
- 1.0 mg/mL
- Storage
- Store the antibody (in aliquots) at -20°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Casein kinase 1 delta phosphorylates tau and disrupts its binding to microtubules.
Cdk5 is a key factor in tau aggregation and tangle formation in vivo.
The environmental toxin arsenite induces tau hyperphosphorylation.
Structure and novel exons of the human tau gene.
The microtubule binding domain of tau protein.
Li G, Yin H, Kuret J
The Journal of biological chemistry 2004 Apr 16;279(16):15938-45
The Journal of biological chemistry 2004 Apr 16;279(16):15938-45
Cdk5 is a key factor in tau aggregation and tangle formation in vivo.
Noble W, Olm V, Takata K, Casey E, Mary O, Meyerson J, Gaynor K, LaFrancois J, Wang L, Kondo T, Davies P, Burns M, Veeranna, Nixon R, Dickson D, Matsuoka Y, Ahlijanian M, Lau LF, Duff K
Neuron 2003 May 22;38(4):555-65
Neuron 2003 May 22;38(4):555-65
The environmental toxin arsenite induces tau hyperphosphorylation.
Giasson BI, Sampathu DM, Wilson CA, Vogelsberg-Ragaglia V, Mushynski WE, Lee VM
Biochemistry 2002 Dec 24;41(51):15376-87
Biochemistry 2002 Dec 24;41(51):15376-87
Structure and novel exons of the human tau gene.
Andreadis A, Brown WM, Kosik KS
Biochemistry 1992 Nov 3;31(43):10626-33
Biochemistry 1992 Nov 3;31(43):10626-33
The microtubule binding domain of tau protein.
Lee G, Neve RL, Kosik KS
Neuron 1989 Jun;2(6):1615-24
Neuron 1989 Jun;2(6):1615-24
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