ABIN196807

antibody from antibodies-online

Targeting: MAPT DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN196807

Provider

antibodies-online

Product name

anti-Microtubule-Associated Protein tau (MAPT) (pThr231) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around the phosphorylation site of Threonine 231 (V-R-Tp-P-P) derived from Human Tau .

Description

Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pThr231

Vial size

50 μL

Concentration

1.0 mg/mL

Storage

Store the antibody (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation.

Babu JR, Geetha T, Wooten MW
Journal of neurochemistry 2005 Jul;94(1):192-203

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Large-scale characterization of HeLa cell nuclear phosphoproteins.

Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP
Proceedings of the National Academy of Sciences of the United States of America 2004 Aug 17;101(33):12130-5

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1H NMR study on the binding of Pin1 Trp-Trp domain with phosphothreonine peptides.

Wintjens R, Wieruszeski JM, Drobecq H, Rousselot-Pailley P, Buée L, Lippens G, Landrieu I
The Journal of biological chemistry 2001 Jul 6;276(27):25150-6

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Tau mutations in frontotemporal dementia FTDP-17 and their relevance for Alzheimer's disease.

Goedert M, Spillantini MG
Biochimica et biophysica acta 2000 Jul 26;1502(1):110-21

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Characterization of in vitro glycation sites of tau.

Nacharaju P, Ko L, Yen SH
Journal of neurochemistry 1997 Oct;69(4):1709-19