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Learn66499-1-Ig
antibody from Proteintech Group
Targeting: MAPT
DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [31]
- Comments [0]
- Validations [0]
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- Product number
- 66499-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- TAU antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated TAU antibody (Cat. #66499-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat, pig and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1E9A8
- Vial size
- 20ul, 150ul
Submitted references Advanced Stem Cell Therapy: 3D-Bioprinted Brain-Like Transplants for Alzheimer's Disease-Like Dementia.
AI-Driven Acceleration of Fluorescence Probe Discovery.
Splicing factor PTBP1 promotes hepatocarcinogenesis via oncogenic splice-switching of MAPT.
Impact of hyaluronic acid-modified hafnium metalorganic frameworks containing rhynchophylline on Alzheimer's disease.
Pleiotropic prodrugs for both symptomatic and disease-modifying treatment of Alzheimer's disease.
A high-throughput drug screening assay for anti-tau aggregation using split GFP and flow cytometry.
C/EBP β/AEP pathway mediates hippocampal mitochondrial damage in a mouse model of sepsis encephalopathy.
A new protocol for the development of organoids based on molecular mechanisms in the developing newborn rat brain: Prospective applications in the study of Alzheimer's disease.
Impact of vitamin A on aged people's cognition and Alzheimer's disease progression in an animal model.
Electroacupuncture attenuates intervertebral disc degeneration by upregulating aquaporins via the cAMP/PKA pathway.
Tyrosine and Phenylalanine Activate Neuronal DNA Repair but Exhibit Opposing Effects on Global Transcription and Adult Female Mice Are Resilient to TyrRS/YARS1 Depletion.
Noninvasive Optogenetics Realized by iPSC-Derived Tentacled Carrier in Alzheimer's Disease Treatment.
Cerebroprotein hydrolysate-I ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via the p53/SAT1/ALOX15 signalling pathway.
RVG29 Peptide-Modified Exosomes Loaded with Mir-133b Mediate the RhoA-ROCK Pathway to Improve Motor and Neurological Symptoms in Parkinson's Disease.
Reprimo (RPRM) mediates neuronal ferroptosis via CREB-Nrf2/SCD1 pathways in radiation-induced brain injury.
Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice.
Tau Aggregation-Dependent Lipid Peroxide Accumulation Driven by the hsa_circ_0001546/14-3-3/CAMK2D/Tau Complex Inhibits Epithelial Ovarian Cancer Peritoneal Metastasis.
Taohe Chengqi decoction improves diabetic cognitive dysfunction by alleviating neural stem cell senescence through HIF1α-driven metabolic signaling.
Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice.
Inhibition of RhoA/ROCK signalling pathway activity improves neural damage and cognitive deficits in the fluorosis model.
Neuroprotection and Mechanism of Gas-miR36-5p from Gastrodia elata in an Alzheimer's Disease Model by Regulating Glycogen Synthase Kinase-3β.
Tubulin Isotypes and Posttranslational Modifications in Vascular Dementia and Alzheimer's Disease.
Acupuncture Effect Assessment in APP/PS1 Transgenic Mice: On Regulating Learning-Memory Abilities, Gut Microbiota, and Microbial Metabolites.
Rapid 3D-STORM imaging of diverse molecular targets in tissue.
Eriodictyol ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via vitamin D receptor-mediated Nrf2 activation.
Acute lead acetate induces neurotoxicity through decreased synaptic plasticity-related protein expression and disordered dendritic formation in nerve cells.
Long-term running exercise alleviates cognitive dysfunction in APP/PSEN1 transgenic mice via enhancing brain lysosomal function.
Salidroside Ameliorates Alzheimer's Disease by Targeting NLRP3 Inflammasome-Mediated Pyroptosis.
The balance of mitochondrial fission and fusion in cortical axons depends on the kinases SadA and SadB.
Melatonin alleviates cognition impairment by antagonizing brain insulin resistance in aged rats fed a high-fat diet.
Cadmium induces actin cytoskeleton alterations and dysfunction in Neuro-2a cells.
Gai K, Song Y, Gao D, Nie Q, Luo X, Xu C, Cai C, Smith A, Li X, Shi W, Zhang L, Sun W, Lin F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(4):e10062
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(4):e10062
AI-Driven Acceleration of Fluorescence Probe Discovery.
Jiang X, Li Y, Tian X, Yang S, Luo R, Zhou C, Liu Y, Hu J, Feng S, Gan L, Ran C, Yu KH, Zhao J, Han X, Zhai X, Jia Y, Dai J, Wang X, Zhu B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e15604
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e15604
Splicing factor PTBP1 promotes hepatocarcinogenesis via oncogenic splice-switching of MAPT.
Zheng W, Shang Y, DU K, Luo A, Pei L, Li M, Zhang G, Deng M
Oncology research 2025;33(5):1121-1133
Oncology research 2025;33(5):1121-1133
Impact of hyaluronic acid-modified hafnium metalorganic frameworks containing rhynchophylline on Alzheimer's disease.
Lin S, Ye Y, Lin S
Open life sciences 2025;20(1):20221043
Open life sciences 2025;20(1):20221043
Pleiotropic prodrugs for both symptomatic and disease-modifying treatment of Alzheimer's disease.
Meden A, Žnidaršič N, Knez D, Wang Y, Xu Z, Yang H, Zhang W, Pišlar A, Perdih A, Brezar SK, Grgurevič N, Pajk S, Sun H, Gobec S
Acta pharmaceutica Sinica. B 2025 Sep;15(9):4807-4828
Acta pharmaceutica Sinica. B 2025 Sep;15(9):4807-4828
A high-throughput drug screening assay for anti-tau aggregation using split GFP and flow cytometry.
Ibrahium OMH, Ademoye TA, Fortin JS, Ostafe R
Scientific reports 2025 Oct 29;15(1):37866
Scientific reports 2025 Oct 29;15(1):37866
C/EBP β/AEP pathway mediates hippocampal mitochondrial damage in a mouse model of sepsis encephalopathy.
Shi Z, Peng Q, Sun S, Xiong M, Zhu X, Wang H, Liu S, Li Z, Wang L, Li G, Zhan L
International immunopharmacology 2025 Oct 10;163:115275
International immunopharmacology 2025 Oct 10;163:115275
A new protocol for the development of organoids based on molecular mechanisms in the developing newborn rat brain: Prospective applications in the study of Alzheimer's disease.
Tzekaki E, Bekiari C, Pantazaki A, Tsantarliotou M, Tsolaki M, Lavrentiadou SN
Journal of neuroscience methods 2025 May;417:110404
Journal of neuroscience methods 2025 May;417:110404
Impact of vitamin A on aged people's cognition and Alzheimer's disease progression in an animal model.
Li P, Xu J, Guo Y, Ma X, Wang X, Liu L, Liu Y, Ren X, Li J, Wang Y, Meng L, Zhou S, Yuan L
NPJ science of food 2025 May 8;9(1):67
NPJ science of food 2025 May 8;9(1):67
Electroacupuncture attenuates intervertebral disc degeneration by upregulating aquaporins via the cAMP/PKA pathway.
Wang M, Huang JB, Zou J, Huang GF
Journal of orthopaedic surgery and research 2025 Mar 25;20(1):310
Journal of orthopaedic surgery and research 2025 Mar 25;20(1):310
Tyrosine and Phenylalanine Activate Neuronal DNA Repair but Exhibit Opposing Effects on Global Transcription and Adult Female Mice Are Resilient to TyrRS/YARS1 Depletion.
Jhanji M, Bhan A, Arrowood C, Yakout DW, Shroff A, McManus D, Gifford H, Vacharasin J, Lizarraga SB, Nazarko TY, Mabb AM, Sajish M
IUBMB life 2025 Jun;77(6):e70030
IUBMB life 2025 Jun;77(6):e70030
Noninvasive Optogenetics Realized by iPSC-Derived Tentacled Carrier in Alzheimer's Disease Treatment.
Zhai Y, Gao F, Shi S, Zhong Q, Zhang J, Fang J, He F, Zhang Y, Li Y, Liu F, Xue B, Gu Y, Li S
Advanced materials (Deerfield Beach, Fla.) 2025 Aug;37(32):e2419768
Advanced materials (Deerfield Beach, Fla.) 2025 Aug;37(32):e2419768
Cerebroprotein hydrolysate-I ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via the p53/SAT1/ALOX15 signalling pathway.
Ren X, Wen Y, Yuan M, Li C, Zhang J, Li S, Zhang X, Wang L, Wang S
European journal of pharmacology 2024 Sep 15;979:176820
European journal of pharmacology 2024 Sep 15;979:176820
RVG29 Peptide-Modified Exosomes Loaded with Mir-133b Mediate the RhoA-ROCK Pathway to Improve Motor and Neurological Symptoms in Parkinson's Disease.
Jiang P, Xiao Y, Hu X, Wang C, Gao H, Huang H, Lv J, Qi Z, Wang Z
ACS biomaterials science & engineering 2024 May 13;10(5):3069-3085
ACS biomaterials science & engineering 2024 May 13;10(5):3069-3085
Reprimo (RPRM) mediates neuronal ferroptosis via CREB-Nrf2/SCD1 pathways in radiation-induced brain injury.
Shi W, Wang J, Li Z, Xu S, Wang J, Zhang L, Yang H
Free radical biology & medicine 2024 Mar;213:343-358
Free radical biology & medicine 2024 Mar;213:343-358
Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice.
Feng T, Du H, Yang C, Wang Y, Hu F
Acta neuropathologica 2024 Mar 25;147(1):62
Acta neuropathologica 2024 Mar 25;147(1):62
Tau Aggregation-Dependent Lipid Peroxide Accumulation Driven by the hsa_circ_0001546/14-3-3/CAMK2D/Tau Complex Inhibits Epithelial Ovarian Cancer Peritoneal Metastasis.
Chai B, Wu Y, Yang H, Fan B, Cao S, Zhang X, Xie Y, Hu Z, Ma Z, Zhang Y, Pan W, Meng W, Meng J, Tian W, Zhang J, Li Y, Shao Y, Wang S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(23):e2310134
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(23):e2310134
Taohe Chengqi decoction improves diabetic cognitive dysfunction by alleviating neural stem cell senescence through HIF1α-driven metabolic signaling.
Qin T, He Z, Hassan HM, Wang Q, Shi L, Yu Y, Zhou Y, Zhang W, Yuan Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156219
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156219
Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice.
Feng T, Du H, Hu F
bioRxiv : the preprint server for biology 2023 Nov 15;
bioRxiv : the preprint server for biology 2023 Nov 15;
Inhibition of RhoA/ROCK signalling pathway activity improves neural damage and cognitive deficits in the fluorosis model.
Lingli C, Hongmei N, Penghuan J, Hongli Z, Yuye L, Rui W, Fei R, Zhihong Y, Dongfang H, Yaming G
Ecotoxicology and environmental safety 2023 Nov 1;266:115554
Ecotoxicology and environmental safety 2023 Nov 1;266:115554
Neuroprotection and Mechanism of Gas-miR36-5p from Gastrodia elata in an Alzheimer's Disease Model by Regulating Glycogen Synthase Kinase-3β.
Lu Z, Fu J, Wu G, Yang Z, Wu X, Wang D, You Z, Nie Z, Sheng Q
International journal of molecular sciences 2023 Dec 9;24(24)
International journal of molecular sciences 2023 Dec 9;24(24)
Tubulin Isotypes and Posttranslational Modifications in Vascular Dementia and Alzheimer's Disease.
Santiago-Mujika E, Luthi-Carter R, Giorgini F, Mukaetova-Ladinska EB
Journal of Alzheimer's disease reports 2022;6(1):739-748
Journal of Alzheimer's disease reports 2022;6(1):739-748
Acupuncture Effect Assessment in APP/PS1 Transgenic Mice: On Regulating Learning-Memory Abilities, Gut Microbiota, and Microbial Metabolites.
Yang B, He M, Chen X, Sun M, Pan T, Xu X, Zhang X, Gong Q, Zhao Y, Jin Z, Cheng Z
Computational and mathematical methods in medicine 2022;2022:1527159
Computational and mathematical methods in medicine 2022;2022:1527159
Rapid 3D-STORM imaging of diverse molecular targets in tissue.
Albrecht NE, Jiang D, Akhanov V, Hobson R, Speer CM, Robichaux MA, Samuel MA
Cell reports methods 2022 Jul 18;2(7):100253
Cell reports methods 2022 Jul 18;2(7):100253
Eriodictyol ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via vitamin D receptor-mediated Nrf2 activation.
Li L, Li WJ, Zheng XR, Liu QL, Du Q, Lai YJ, Liu SQ
Molecular medicine (Cambridge, Mass.) 2022 Jan 29;28(1):11
Molecular medicine (Cambridge, Mass.) 2022 Jan 29;28(1):11
Acute lead acetate induces neurotoxicity through decreased synaptic plasticity-related protein expression and disordered dendritic formation in nerve cells.
Chen L, Liu Y, Jia P, Zhang H, Yin Z, Hu D, Ning H, Ge Y
Environmental science and pollution research international 2022 Aug;29(39):58927-58935
Environmental science and pollution research international 2022 Aug;29(39):58927-58935
Long-term running exercise alleviates cognitive dysfunction in APP/PSEN1 transgenic mice via enhancing brain lysosomal function.
Wang X, Zhu YT, Zhu Y, Sun YL, Huang J, Li Z, Wang Y, Wu JC, Qin ZH, Lin F
Acta pharmacologica Sinica 2022 Apr;43(4):850-861
Acta pharmacologica Sinica 2022 Apr;43(4):850-861
Salidroside Ameliorates Alzheimer's Disease by Targeting NLRP3 Inflammasome-Mediated Pyroptosis.
Cai Y, Chai Y, Fu Y, Wang Y, Zhang Y, Zhang X, Zhu L, Miao M, Yan T
Frontiers in aging neuroscience 2021;13:809433
Frontiers in aging neuroscience 2021;13:809433
The balance of mitochondrial fission and fusion in cortical axons depends on the kinases SadA and SadB.
Di Meo D, Ravindran P, Sadhanasatish T, Dhumale P, Püschel AW
Cell reports 2021 Dec 21;37(12):110141
Cell reports 2021 Dec 21;37(12):110141
Melatonin alleviates cognition impairment by antagonizing brain insulin resistance in aged rats fed a high-fat diet.
Xu J, Gao H, Zhang L, Rong S, Yang W, Ma C, Chen M, Huang Q, Deng Q, Huang F
Journal of pineal research 2019 Sep;67(2):e12584
Journal of pineal research 2019 Sep;67(2):e12584
Cadmium induces actin cytoskeleton alterations and dysfunction in Neuro-2a cells.
Ge Y, Song X, Chen L, Hu D, Hua L, Cui Y, Liu J, An Z, Yin Z, Ning H
Environmental toxicology 2019 Apr;34(4):469-475
Environmental toxicology 2019 Apr;34(4):469-475
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