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LearnMA5-12805
antibody from Invitrogen Antibodies
Targeting: MAPT
DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [58]
- Comments [0]
- Validations
- Western blot [1]
- Other assay [3]
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- Product number
- MA5-12805 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Tau Monoclonal Antibody (TAU-5), Biotin
- Antibody type
- Monoclonal
- Antigen
- Purifed from natural sources
- Description
- MA5-12805 targets TAU in IF, IP, and WB applications and shows reactivity with Bovine, Human, mouse, Ovine, and Rat samples.
- Conjugate
- Biotin
- Antibody clone number
- TAU-5
- Concentration
- 0.2 mg/mL
Submitted references Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction.
Memantine Differentially Regulates Tau Phosphorylation Induced by Chronic Restraint Stress of Varying Duration in Mice.
A soluble truncated tau species related to cognitive dysfunction and caspase-2 is elevated in the brain of Huntington's disease patients.
Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease.
Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin-induced tau hyperphosphorylation and cognitive injuries in rat hippocampi.
Alzheimer's disease related markers, cellular toxicity and behavioral deficits induced six weeks after oligomeric amyloid-β peptide injection in rats.
Nmnat2 attenuates Tau phosphorylation through activation of PP2A.
Generation and characterization of a rabbit monoclonal antibody site-specific for tau O-GlcNAcylated at serine 400.
Glycation exacerbates the neuronal toxicity of β-amyloid.
Ser9 phosphorylation causes cytoplasmic detention of I2PP2A/SET in Alzheimer disease.
Overexpression of RCAN1 isoform 4 in mouse neurons leads to a moderate behavioral impairment.
NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.
Bip enhanced the association of GSK-3β with tau during ER stress both in vivo and in vitro.
Expression of the hyperphosphorylated tau attenuates ER stress-induced apoptosis with upregulation of unfolded protein response.
Tumor necrosis factor-α synthesis inhibitor 3,6'-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer's disease.
Targeting hyperphosphorylated tau with sodium selenate suppresses seizures in rodent models.
Lidocaine attenuates cognitive impairment after isoflurane anesthesia in old rats.
A proteomic analysis of MCLR-induced neurotoxicity: implications for Alzheimer's disease.
AGEs induce Alzheimer-like tau pathology and memory deficit via RAGE-mediated GSK-3 activation.
Neuroglobin attenuates Alzheimer-like tau hyperphosphorylation by activating Akt signaling.
Methylglyoxal induces tau hyperphosphorylation via promoting AGEs formation.
Enriched environment prevents cognitive impairment and tau hyperphosphorylation after chronic cerebral hypoperfusion.
Enriched environment prevents cognitive impairment and tau hyperphosphorylation after chronic cerebral hypoperfusion.
Folate/vitamin-B12 prevents chronic hyperhomocysteinemia-induced tau hyperphosphorylation and memory deficits in aged rats.
Berberine attenuates calyculin A-induced cytotoxicity and Tau hyperphosphorylation in HEK293 cells.
Combined expression of tau and the Harlequin mouse mutation leads to increased mitochondrial dysfunction, tau pathology and neurodegeneration.
AMPK activation inhibits apoptosis and tau hyperphosphorylation mediated by palmitate in SH-SY5Y cells.
Fuzhisan, a Chinese herbal medicine, inhibits beta-amyloid-induced neurotoxicity and tau phosphorylation through calpain/Cdk5 pathway in cultured cortical neurons.
Inhibition of glycogen synthase kinase-3β by Angelica sinensis extract decreases β-amyloid-induced neurotoxicity and tau phosphorylation in cultured cortical neurons.
Mapping O-GlcNAc modification sites on tau and generation of a site-specific O-GlcNAc tau antibody.
Altered phosphorylation but no neurodegeneration in a mouse model of tau hyperphosphorylation.
LiCl attenuates thapsigargin-induced tau hyperphosphorylation by inhibiting GSK-3β in vivo and in vitro.
LiCl attenuates thapsigargin-induced tau hyperphosphorylation by inhibiting GSK-3β in vivo and in vitro.
Tau dephosphorylation potentiates apoptosis by mechanisms involving a failed dephosphorylation/activation of Bcl-2.
A comparative study of Lrrk2 function in primary neuronal cultures.
Protective effect of isoflavones against homocysteine-mediated neuronal degeneration in SH-SY5Y cells.
Inhibition of autophagy causes tau proteolysis by activating calpain in rat brain.
Isoflavones prevent endoplasmic reticulum stress-mediated neuronal degeneration by inhibiting tau hyperphosphorylation in SH-SY5Y cells.
Estradiol attenuates tau hyperphosphorylation induced by upregulation of protein kinase-A.
Activation of glycogen synthase kinase-3 inhibits protein phosphatase-2A and the underlying mechanisms.
17beta-estradiol attenuates glycogen synthase kinase-3beta activation and tau hyperphosphorylation in Akt-independent manner.
Up-regulation of tau, a brain microtubule-associated protein, in lens cortical fractions of aged alphaA-, alphaB-, and alphaA/B-crystallin knockout mice.
Effects of tau phosphorylation on proteasome activity.
The involvement of glycogen synthase kinase-3 and protein phosphatase-2A in lactacystin-induced tau accumulation.
The marijuana component cannabidiol inhibits beta-amyloid-induced tau protein hyperphosphorylation through Wnt/beta-catenin pathway rescue in PC12 cells.
EWS-FLI1 fusion protein up-regulates critical genes in neural crest development and is responsible for the observed phenotype of Ewing's family of tumors.
Abnormal group I metabotropic glutamate receptor expression and signaling in the frontal cortex in Pick disease.
Abnormal group I metabotropic glutamate receptor expression and signaling in the frontal cortex in Pick disease.
Nitration and oligomerization of tau induced by peroxynitrite inhibit its microtubule-binding activity.
Mutations in the tau gene that cause an increase in three repeat tau and frontotemporal dementia.
Mutations in the tau gene that cause an increase in three repeat tau and frontotemporal dementia.
Partial rescue of the p35-/- brain phenotype by low expression of a neuronal-specific enolase p25 transgene.
Partial rescue of the p35-/- brain phenotype by low expression of a neuronal-specific enolase p25 transgene.
Rapid detection of protein aggregates in the brains of Alzheimer patients and transgenic mouse models of amyloidosis.
Rapid detection of protein aggregates in the brains of Alzheimer patients and transgenic mouse models of amyloidosis.
Hydrogen peroxide induces transient dephosphorylation of tau protein in cultured rat oligodendrocytes.
Hydrogen peroxide induces transient dephosphorylation of tau protein in cultured rat oligodendrocytes.
Reduced protein phosphatase 2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice.
Zhang X, Zou L, Meng L, Xiong M, Pan L, Chen G, Zheng Y, Xiong J, Wang Z, Duong DM, Zhang Z, Cao X, Wang T, Tang L, Ye K, Zhang Z
eLife 2021 May 21;10
eLife 2021 May 21;10
Memantine Differentially Regulates Tau Phosphorylation Induced by Chronic Restraint Stress of Varying Duration in Mice.
Liu Y, Cao L, Zhang X, Liang Y, Xu Y, Zhu C
Neural plasticity 2019;2019:4168472
Neural plasticity 2019;2019:4168472
A soluble truncated tau species related to cognitive dysfunction and caspase-2 is elevated in the brain of Huntington's disease patients.
Liu P, Smith BR, Huang ES, Mahesh A, Vonsattel JPG, Petersen AJ, Gomez-Pastor R, Ashe KH
Acta neuropathologica communications 2019 Jul 30;7(1):111
Acta neuropathologica communications 2019 Jul 30;7(1):111
Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease.
Zhang Z, Obianyo O, Dall E, Du Y, Fu H, Liu X, Kang SS, Song M, Yu SP, Cabrele C, Schubert M, Li X, Wang JZ, Brandstetter H, Ye K
Nature communications 2017 Mar 27;8:14740
Nature communications 2017 Mar 27;8:14740
Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin-induced tau hyperphosphorylation and cognitive injuries in rat hippocampi.
Du LL, Xie JZ, Cheng XS, Li XH, Kong FL, Jiang X, Ma ZW, Wang JZ, Chen C, Zhou XW
Age (Dordrecht, Netherlands) 2014 Apr;36(2):613-23
Age (Dordrecht, Netherlands) 2014 Apr;36(2):613-23
Alzheimer's disease related markers, cellular toxicity and behavioral deficits induced six weeks after oligomeric amyloid-β peptide injection in rats.
Zussy C, Brureau A, Keller E, Marchal S, Blayo C, Delair B, Ixart G, Maurice T, Givalois L
PloS one 2013;8(1):e53117
PloS one 2013;8(1):e53117
Nmnat2 attenuates Tau phosphorylation through activation of PP2A.
Cheng XS, Zhao KP, Jiang X, Du LL, Li XH, Ma ZW, Yao J, Luo Y, Duan DX, Wang JZ, Zhou XW
Journal of Alzheimer's disease : JAD 2013;36(1):185-95
Journal of Alzheimer's disease : JAD 2013;36(1):185-95
Generation and characterization of a rabbit monoclonal antibody site-specific for tau O-GlcNAcylated at serine 400.
Cameron A, Giacomozzi B, Joyce J, Gray A, Graham D, Ousson S, Neny M, Beher D, Carlson G, O'Moore J, Shearman M, Hering H
FEBS letters 2013 Nov 15;587(22):3722-8
FEBS letters 2013 Nov 15;587(22):3722-8
Glycation exacerbates the neuronal toxicity of β-amyloid.
Li XH, Du LL, Cheng XS, Jiang X, Zhang Y, Lv BL, Liu R, Wang JZ, Zhou XW
Cell death & disease 2013 Jun 13;4(6):e673
Cell death & disease 2013 Jun 13;4(6):e673
Ser9 phosphorylation causes cytoplasmic detention of I2PP2A/SET in Alzheimer disease.
Yu G, Yan T, Feng Y, Liu X, Xia Y, Luo H, Wang JZ, Wang X
Neurobiology of aging 2013 Jul;34(7):1748-58
Neurobiology of aging 2013 Jul;34(7):1748-58
Overexpression of RCAN1 isoform 4 in mouse neurons leads to a moderate behavioral impairment.
Bhoiwala DL, Koleilat I, Qian J, Beyer B, Hushmendy SF, Mathew A, Bhoiwala DL, Ferland RJ, Crawford DR
Neurological research 2013 Jan;35(1):79-89
Neurological research 2013 Jan;35(1):79-89
NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.
Tackenberg C, Grinschgl S, Trutzel A, Santuccione AC, Frey MC, Konietzko U, Grimm J, Brandt R, Nitsch RM
Cell death & disease 2013 Apr 25;4(4):e608
Cell death & disease 2013 Apr 25;4(4):e608
Bip enhanced the association of GSK-3β with tau during ER stress both in vivo and in vitro.
Liu ZC, Fu ZQ, Song J, Zhang JY, Wei YP, Chu J, Han L, Qu N, Wang JZ, Tian Q
Journal of Alzheimer's disease : JAD 2012;29(4):727-40
Journal of Alzheimer's disease : JAD 2012;29(4):727-40
Expression of the hyperphosphorylated tau attenuates ER stress-induced apoptosis with upregulation of unfolded protein response.
Liu XA, Song J, Jiang Q, Wang Q, Tian Q, Wang JZ
Apoptosis : an international journal on programmed cell death 2012 Oct;17(10):1039-49
Apoptosis : an international journal on programmed cell death 2012 Oct;17(10):1039-49
Tumor necrosis factor-α synthesis inhibitor 3,6'-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer's disease.
Tweedie D, Ferguson RA, Fishman K, Frankola KA, Van Praag H, Holloway HW, Luo W, Li Y, Caracciolo L, Russo I, Barlati S, Ray B, Lahiri DK, Bosetti F, Greig NH, Rosi S
Journal of neuroinflammation 2012 May 29;9:106
Journal of neuroinflammation 2012 May 29;9:106
Targeting hyperphosphorylated tau with sodium selenate suppresses seizures in rodent models.
Jones NC, Nguyen T, Corcoran NM, Velakoulis D, Chen T, Grundy R, O'Brien TJ, Hovens CM
Neurobiology of disease 2012 Mar;45(3):897-901
Neurobiology of disease 2012 Mar;45(3):897-901
Lidocaine attenuates cognitive impairment after isoflurane anesthesia in old rats.
Lin D, Cao L, Wang Z, Li J, Washington JM, Zuo Z
Behavioural brain research 2012 Mar 17;228(2):319-27
Behavioural brain research 2012 Mar 17;228(2):319-27
A proteomic analysis of MCLR-induced neurotoxicity: implications for Alzheimer's disease.
Li G, Cai F, Yan W, Li C, Wang J
Toxicological sciences : an official journal of the Society of Toxicology 2012 Jun;127(2):485-95
Toxicological sciences : an official journal of the Society of Toxicology 2012 Jun;127(2):485-95
AGEs induce Alzheimer-like tau pathology and memory deficit via RAGE-mediated GSK-3 activation.
Li XH, Lv BL, Xie JZ, Liu J, Zhou XW, Wang JZ
Neurobiology of aging 2012 Jul;33(7):1400-10
Neurobiology of aging 2012 Jul;33(7):1400-10
Neuroglobin attenuates Alzheimer-like tau hyperphosphorylation by activating Akt signaling.
Chen LM, Xiong YS, Kong FL, Qu M, Wang Q, Chen XQ, Wang JZ, Zhu LQ
Journal of neurochemistry 2012 Jan;120(1):157-64
Journal of neurochemistry 2012 Jan;120(1):157-64
Methylglyoxal induces tau hyperphosphorylation via promoting AGEs formation.
Li XH, Xie JZ, Jiang X, Lv BL, Cheng XS, Du LL, Zhang JY, Wang JZ, Zhou XW
Neuromolecular medicine 2012 Dec;14(4):338-48
Neuromolecular medicine 2012 Dec;14(4):338-48
Enriched environment prevents cognitive impairment and tau hyperphosphorylation after chronic cerebral hypoperfusion.
Yao ZH, Zhang JJ, Xie XF
Current neurovascular research 2012 Aug;9(3):176-84
Current neurovascular research 2012 Aug;9(3):176-84
Enriched environment prevents cognitive impairment and tau hyperphosphorylation after chronic cerebral hypoperfusion.
Yao ZH, Zhang JJ, Xie XF
Current neurovascular research 2012 Aug;9(3):176-84
Current neurovascular research 2012 Aug;9(3):176-84
Folate/vitamin-B12 prevents chronic hyperhomocysteinemia-induced tau hyperphosphorylation and memory deficits in aged rats.
Wei W, Liu YH, Zhang CE, Wang Q, Wei Z, Mousseau DD, Wang JZ, Tian Q, Liu GP
Journal of Alzheimer's disease : JAD 2011;27(3):639-50
Journal of Alzheimer's disease : JAD 2011;27(3):639-50
Berberine attenuates calyculin A-induced cytotoxicity and Tau hyperphosphorylation in HEK293 cells.
Yu G, Li Y, Tian Q, Liu R, Wang Q, Wang JZ, Wang X
Journal of Alzheimer's disease : JAD 2011;24(3):525-35
Journal of Alzheimer's disease : JAD 2011;24(3):525-35
Combined expression of tau and the Harlequin mouse mutation leads to increased mitochondrial dysfunction, tau pathology and neurodegeneration.
Kulic L, Wollmer MA, Rhein V, Pagani L, Kuehnle K, Cattepoel S, Tracy J, Eckert A, Nitsch RM
Neurobiology of aging 2011 Oct;32(10):1827-38
Neurobiology of aging 2011 Oct;32(10):1827-38
AMPK activation inhibits apoptosis and tau hyperphosphorylation mediated by palmitate in SH-SY5Y cells.
Kim J, Park YJ, Jang Y, Kwon YH
Brain research 2011 Oct 18;1418:42-51
Brain research 2011 Oct 18;1418:42-51
Fuzhisan, a Chinese herbal medicine, inhibits beta-amyloid-induced neurotoxicity and tau phosphorylation through calpain/Cdk5 pathway in cultured cortical neurons.
Zhang Z, Zhao R, Tang Y, Wen S, Wang D, Qi J
Neurochemical research 2011 May;36(5):801-11
Neurochemical research 2011 May;36(5):801-11
Inhibition of glycogen synthase kinase-3β by Angelica sinensis extract decreases β-amyloid-induced neurotoxicity and tau phosphorylation in cultured cortical neurons.
Zhang Z, Zhao R, Qi J, Wen S, Tang Y, Wang D
Journal of neuroscience research 2011 Mar;89(3):437-47
Journal of neuroscience research 2011 Mar;89(3):437-47
Mapping O-GlcNAc modification sites on tau and generation of a site-specific O-GlcNAc tau antibody.
Yuzwa SA, Yadav AK, Skorobogatko Y, Clark T, Vosseller K, Vocadlo DJ
Amino acids 2011 Mar;40(3):857-68
Amino acids 2011 Mar;40(3):857-68
Altered phosphorylation but no neurodegeneration in a mouse model of tau hyperphosphorylation.
Hundelt M, Fath T, Selle K, Oesterwind K, Jordan J, Schultz C, Götz J, von Engelhardt J, Monyer H, Lewejohann L, Sachser N, Bakota L, Brandt R
Neurobiology of aging 2011 Jun;32(6):991-1006
Neurobiology of aging 2011 Jun;32(6):991-1006
LiCl attenuates thapsigargin-induced tau hyperphosphorylation by inhibiting GSK-3β in vivo and in vitro.
Fu ZQ, Yang Y, Song J, Jiang Q, Lin ZC, Wang Q, Zhu LQ, Wang JZ, Tian Q
Journal of Alzheimer's disease : JAD 2010;21(4):1107-17
Journal of Alzheimer's disease : JAD 2010;21(4):1107-17
LiCl attenuates thapsigargin-induced tau hyperphosphorylation by inhibiting GSK-3β in vivo and in vitro.
Fu ZQ, Yang Y, Song J, Jiang Q, Lin ZC, Wang Q, Zhu LQ, Wang JZ, Tian Q
Journal of Alzheimer's disease : JAD 2010;21(4):1107-17
Journal of Alzheimer's disease : JAD 2010;21(4):1107-17
Tau dephosphorylation potentiates apoptosis by mechanisms involving a failed dephosphorylation/activation of Bcl-2.
Liu XA, Liao K, Liu R, Wang HH, Zhang Y, Zhang Q, Wang Q, Li HL, Tian Q, Wang JZ
Journal of Alzheimer's disease : JAD 2010;19(3):953-62
Journal of Alzheimer's disease : JAD 2010;19(3):953-62
A comparative study of Lrrk2 function in primary neuronal cultures.
Dächsel JC, Behrouz B, Yue M, Beevers JE, Melrose HL, Farrer MJ
Parkinsonism & related disorders 2010 Dec;16(10):650-5
Parkinsonism & related disorders 2010 Dec;16(10):650-5
Protective effect of isoflavones against homocysteine-mediated neuronal degeneration in SH-SY5Y cells.
Park YJ, Jang Y, Kwon YH
Amino acids 2010 Aug;39(3):785-94
Amino acids 2010 Aug;39(3):785-94
Inhibition of autophagy causes tau proteolysis by activating calpain in rat brain.
Zhang JY, Peng C, Shi H, Wang S, Wang Q, Wang JZ
Journal of Alzheimer's disease : JAD 2009;16(1):39-47
Journal of Alzheimer's disease : JAD 2009;16(1):39-47
Isoflavones prevent endoplasmic reticulum stress-mediated neuronal degeneration by inhibiting tau hyperphosphorylation in SH-SY5Y cells.
Park YJ, Jang YM, Kwon YH
Journal of medicinal food 2009 Jun;12(3):528-35
Journal of medicinal food 2009 Jun;12(3):528-35
Estradiol attenuates tau hyperphosphorylation induced by upregulation of protein kinase-A.
Liu XA, Zhu LQ, Zhang Q, Shi HR, Wang SH, Wang Q, Wang JZ
Neurochemical research 2008 Sep;33(9):1811-20
Neurochemical research 2008 Sep;33(9):1811-20
Activation of glycogen synthase kinase-3 inhibits protein phosphatase-2A and the underlying mechanisms.
Liu GP, Zhang Y, Yao XQ, Zhang CE, Fang J, Wang Q, Wang JZ
Neurobiology of aging 2008 Sep;29(9):1348-58
Neurobiology of aging 2008 Sep;29(9):1348-58
17beta-estradiol attenuates glycogen synthase kinase-3beta activation and tau hyperphosphorylation in Akt-independent manner.
Shi HR, Zhu LQ, Wang SH, Liu XA, Tian Q, Zhang Q, Wang Q, Wang JZ
Journal of neural transmission (Vienna, Austria : 1996) 2008 Jun;115(6):879-88
Journal of neural transmission (Vienna, Austria : 1996) 2008 Jun;115(6):879-88
Up-regulation of tau, a brain microtubule-associated protein, in lens cortical fractions of aged alphaA-, alphaB-, and alphaA/B-crystallin knockout mice.
Bai F, Xi JH, Andley UP
Molecular vision 2007 Sep 6;13:1589-600
Molecular vision 2007 Sep 6;13:1589-600
Effects of tau phosphorylation on proteasome activity.
Ren QG, Liao XM, Chen XQ, Liu GP, Wang JZ
FEBS letters 2007 Apr 3;581(7):1521-8
FEBS letters 2007 Apr 3;581(7):1521-8
The involvement of glycogen synthase kinase-3 and protein phosphatase-2A in lactacystin-induced tau accumulation.
Ren QG, Liao XM, Wang ZF, Qu ZS, Wang JZ
FEBS letters 2006 May 1;580(10):2503-11
FEBS letters 2006 May 1;580(10):2503-11
The marijuana component cannabidiol inhibits beta-amyloid-induced tau protein hyperphosphorylation through Wnt/beta-catenin pathway rescue in PC12 cells.
Esposito G, De Filippis D, Carnuccio R, Izzo AA, Iuvone T
Journal of molecular medicine (Berlin, Germany) 2006 Mar;84(3):253-8
Journal of molecular medicine (Berlin, Germany) 2006 Mar;84(3):253-8
EWS-FLI1 fusion protein up-regulates critical genes in neural crest development and is responsible for the observed phenotype of Ewing's family of tumors.
Hu-Lieskovan S, Zhang J, Wu L, Shimada H, Schofield DE, Triche TJ
Cancer research 2005 Jun 1;65(11):4633-44
Cancer research 2005 Jun 1;65(11):4633-44
Abnormal group I metabotropic glutamate receptor expression and signaling in the frontal cortex in Pick disease.
Dalfó E, Albasanz JL, Rodríguez A, Martín M, Ferrer I
Journal of neuropathology and experimental neurology 2005 Jul;64(7):638-47
Journal of neuropathology and experimental neurology 2005 Jul;64(7):638-47
Abnormal group I metabotropic glutamate receptor expression and signaling in the frontal cortex in Pick disease.
Dalfó E, Albasanz JL, Rodríguez A, Martín M, Ferrer I
Journal of neuropathology and experimental neurology 2005 Jul;64(7):638-47
Journal of neuropathology and experimental neurology 2005 Jul;64(7):638-47
Nitration and oligomerization of tau induced by peroxynitrite inhibit its microtubule-binding activity.
Zhang YJ, Xu YF, Chen XQ, Wang XC, Wang JZ
FEBS letters 2005 Apr 25;579(11):2421-7
FEBS letters 2005 Apr 25;579(11):2421-7
Mutations in the tau gene that cause an increase in three repeat tau and frontotemporal dementia.
Stanford PM, Shepherd CE, Halliday GM, Brooks WS, Schofield PW, Brodaty H, Martins RN, Kwok JB, Schofield PR
Brain : a journal of neurology 2003 Apr;126(Pt 4):814-26
Brain : a journal of neurology 2003 Apr;126(Pt 4):814-26
Mutations in the tau gene that cause an increase in three repeat tau and frontotemporal dementia.
Stanford PM, Shepherd CE, Halliday GM, Brooks WS, Schofield PW, Brodaty H, Martins RN, Kwok JB, Schofield PR
Brain : a journal of neurology 2003 Apr;126(Pt 4):814-26
Brain : a journal of neurology 2003 Apr;126(Pt 4):814-26
Partial rescue of the p35-/- brain phenotype by low expression of a neuronal-specific enolase p25 transgene.
Patzke H, Maddineni U, Ayala R, Morabito M, Volker J, Dikkes P, Ahlijanian MK, Tsai LH
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 Apr 1;23(7):2769-78
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 Apr 1;23(7):2769-78
Partial rescue of the p35-/- brain phenotype by low expression of a neuronal-specific enolase p25 transgene.
Patzke H, Maddineni U, Ayala R, Morabito M, Volker J, Dikkes P, Ahlijanian MK, Tsai LH
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 Apr 1;23(7):2769-78
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 Apr 1;23(7):2769-78
Rapid detection of protein aggregates in the brains of Alzheimer patients and transgenic mouse models of amyloidosis.
Xu G, Gonzales V, Borchelt DR
Alzheimer disease and associated disorders 2002 Jul-Sep;16(3):191-5
Alzheimer disease and associated disorders 2002 Jul-Sep;16(3):191-5
Rapid detection of protein aggregates in the brains of Alzheimer patients and transgenic mouse models of amyloidosis.
Xu G, Gonzales V, Borchelt DR
Alzheimer disease and associated disorders 2002 Jul-Sep;16(3):191-5
Alzheimer disease and associated disorders 2002 Jul-Sep;16(3):191-5
Hydrogen peroxide induces transient dephosphorylation of tau protein in cultured rat oligodendrocytes.
LoPresti P, Konat GW
Neuroscience letters 2001 Sep 28;311(2):142-4
Neuroscience letters 2001 Sep 28;311(2):142-4
Hydrogen peroxide induces transient dephosphorylation of tau protein in cultured rat oligodendrocytes.
LoPresti P, Konat GW
Neuroscience letters 2001 Sep 28;311(2):142-4
Neuroscience letters 2001 Sep 28;311(2):142-4
Reduced protein phosphatase 2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice.
Kins S, Crameri A, Evans DR, Hemmings BA, Nitsch RM, Gotz J
The Journal of biological chemistry 2001 Oct 12;276(41):38193-200
The Journal of biological chemistry 2001 Oct 12;276(41):38193-200
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot of TAU using TAU Monoclonal Antibody (Product # MA5-12805) on IMR-5 Cells.
- Conjugate
- Biotin
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunoprecipitation of TAU using TAU Monoclonal Antibody (Product # MA5-12805) on denatured Human IMR-5 Cells.
- Conjugate
- Biotin
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Conjugate
- Biotin
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 4 Compound 11 inhibits delta-secretase activity and restores cognitive deficits in tau P301S mouse model. ( a ) delta-secretase activity assay. Non-transgenic control mice or tau P301S mice were treated with compound 11 or vehicle at 10 mg kg -1 d -1 for 3 months. Compound 11 significantly decreased the activity of delta-secretase in the brain (mean+-s.e.m.; n =4 mice per group; * P
- Conjugate
- Biotin
