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- Antigen structure
- References [14]
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- Product number
- 21430-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21430-1-AP, RRID:AB_10858637
- Product name
- SLC24A6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SLC24A6 antibody (Cat. #21430-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references STOML2 Alleviates Osteoarthritis by Regulating Mitochondrial Energy Metabolism and Oxidative Stress.
Chronic cold exposure induces plasticity of mitochondrial calcium uptake in beige and brown fat of UCP1-deficient mice.
Cell-type-specific dysregulation of mitochondrial calcium signaling in Alzheimer's disease.
TMEM65-dependent Ca2+ extrusion safeguards mitochondrial homeostasis.
O-GlcNAcylation of circadian clock protein Bmal1 impairs cognitive function in diabetic mice.
High glucose impairs cognitive function through inducing mitochondrial calcium overload in Treg cells.
Mfn2 induces NCLX-mediated calcium release from mitochondria.
The mitochondrial fusion protein OPA1 is dispensable in the liver and its absence induces mitohormesis to protect liver from drug-induced injury.
Dihydroartemisinin inhibits liver cancer cell migration and invasion by reducing ATP synthase production through CaMKK2/NCLX.
The effect of regulating MCU expression on experimental ischemic brain injury.
CD137 Signal Mediates Cardiac Ischemia-Reperfusion Injury by Regulating the Necrosis of Cardiomyocytes.
Lon upregulation contributes to cisplatin resistance by triggering NCLX-mediated mitochondrial Ca(2+) release in cancer cells.
Astragalus Polysaccharides Reduce High-glucose-induced Rat Aortic Endothelial Cell Senescence and Inflammasome Activation by Modulating the Mitochondrial Na(+)/Ca(2+) Exchanger.
The mitochondrial Na(+)/Ca(2+) exchanger may reduce high glucose-induced oxidative stress and nucleotide-binding oligomerization domain receptor 3 inflammasome activation in endothelial cells.
Xie F, Miao K, Wu H, Wu X
Genetics research 2026;2026(1):e9303825
Genetics research 2026;2026(1):e9303825
Chronic cold exposure induces plasticity of mitochondrial calcium uptake in beige and brown fat of UCP1-deficient mice.
Chamorro CG, Pathuri S, Acin-Perez R, Chhan M, Milner MG, Ermolova N, Jones AE, Divakaruni AS, Stiles L, Hevener AL, Zhou Z, Shirihai OS, Kirichok Y, Bertholet AM
bioRxiv : the preprint server for biology 2026 Mar 18;
bioRxiv : the preprint server for biology 2026 Mar 18;
Cell-type-specific dysregulation of mitochondrial calcium signaling in Alzheimer's disease.
Shukla S, Kadam AA, Goyani S, Jaiswal N, Samantaray K, Raghav D, Kashyap S, Tomar D, Jadiya P
Cell communication and signaling : CCS 2025 Nov 3;23(1):472
Cell communication and signaling : CCS 2025 Nov 3;23(1):472
TMEM65-dependent Ca2+ extrusion safeguards mitochondrial homeostasis.
Vetralla M, Wischhof L, Kahsay A, Cadenelli V, Scifo E, Xie B, Sbrissa M, Habert MS, Ehninger D, Rizzuto R, Bano D, De Stefani D
Nature communications 2025 Dec 17;17(1):923
Nature communications 2025 Dec 17;17(1):923
O-GlcNAcylation of circadian clock protein Bmal1 impairs cognitive function in diabetic mice.
Hui Y, Zhong Y, Kuang L, Xu J, Hao Y, Cao J, Zheng T
The EMBO journal 2024 Nov;43(22):5667-5689
The EMBO journal 2024 Nov;43(22):5667-5689
High glucose impairs cognitive function through inducing mitochondrial calcium overload in Treg cells.
Hui Y, Kuang L, Zhong Y, Tang Y, Xu Z, Zheng T
iScience 2024 Jan 19;27(1):108689
iScience 2024 Jan 19;27(1):108689
Mfn2 induces NCLX-mediated calcium release from mitochondria.
Kolitsida P, Saha A, Caliri A, Assali E, Riera AM, Itskanov S, Magana CS, Stork B, Shirihai O, Sekler I, Koehler CM, van der Bliek AM
bioRxiv : the preprint server for biology 2024 Aug 13;
bioRxiv : the preprint server for biology 2024 Aug 13;
The mitochondrial fusion protein OPA1 is dispensable in the liver and its absence induces mitohormesis to protect liver from drug-induced injury.
Lee H, Lee TJ, Galloway CA, Zhi W, Xiao W, de Mesy Bentley KL, Sharma A, Teng Y, Sesaki H, Yoon Y
Nature communications 2023 Oct 23;14(1):6721
Nature communications 2023 Oct 23;14(1):6721
Dihydroartemisinin inhibits liver cancer cell migration and invasion by reducing ATP synthase production through CaMKK2/NCLX.
Chang J, Xin C, Wang Y, Wang Y
Oncology letters 2023 Dec;26(6):540
Oncology letters 2023 Dec;26(6):540
The effect of regulating MCU expression on experimental ischemic brain injury.
Qin J, Liu L, Liu L, Zhou Z, Zhou Y, Zhang K, Wang B, Lu H, Ran J, Ma T, Zhang Y, Li Z, Liu X
Experimental neurology 2023 Apr;362:114329
Experimental neurology 2023 Apr;362:114329
CD137 Signal Mediates Cardiac Ischemia-Reperfusion Injury by Regulating the Necrosis of Cardiomyocytes.
Xu Y, Chen R, Yan J, Zang G, Shao C, Wang Z
Journal of cardiovascular translational research 2022 Oct;15(5):1163-1175
Journal of cardiovascular translational research 2022 Oct;15(5):1163-1175
Lon upregulation contributes to cisplatin resistance by triggering NCLX-mediated mitochondrial Ca(2+) release in cancer cells.
Tangeda V, Lo YK, Babuharisankar AP, Chou HY, Kuo CL, Kao YH, Lee AY, Chang JY
Cell death & disease 2022 Mar 16;13(3):241
Cell death & disease 2022 Mar 16;13(3):241
Astragalus Polysaccharides Reduce High-glucose-induced Rat Aortic Endothelial Cell Senescence and Inflammasome Activation by Modulating the Mitochondrial Na(+)/Ca(2+) Exchanger.
Miao XY, Zhu XX, Gu ZY, Fu B, Cui SY, Zu Y, Rong LJ, Hu F, Chen XM, Gong YP, Li CL
Cell biochemistry and biophysics 2022 Jun;80(2):341-353
Cell biochemistry and biophysics 2022 Jun;80(2):341-353
The mitochondrial Na(+)/Ca(2+) exchanger may reduce high glucose-induced oxidative stress and nucleotide-binding oligomerization domain receptor 3 inflammasome activation in endothelial cells.
Zu Y, Wan LJ, Cui SY, Gong YP, Li CL
Journal of geriatric cardiology : JGC 2015 May;12(3):270-8
Journal of geriatric cardiology : JGC 2015 May;12(3):270-8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SLC24A6 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human SLC24A6. This antibody recognizes human antigen. The SLC24A6 antibody has been validated for the following applications: ELISA, WB analysis.
