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- Antibody Data
- Antigen structure
- References [150]
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- Product number
- 12594-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12594-1-AP, RRID:AB_2130085
- Product name
- Integrin Beta 1 antibody
- Antibody type
- Polyclonal
- Description
- Integrin Beta 1 antibody (Cat. #12594-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Photocrosslinkable Chitosan Quaternary Ammonium Salt-Based Ternary Hydrogel with Fibroblast Growth Factor 21 for Diabetic Wound Healing.
Endothelial SMAD1-MCAM axis facilitates sunitinib resistance and progression of clear cell renal cell carcinoma via LAMB1-ITGB1 signaling.
A pH-Responsive Biomimetic Antioxidant Nanoplatform with Dual Renal Targeting for Synergistic Therapy of Acute Kidney Injury.
Tenascin C(+) myofibroblasts exacerbate vascular neointimal hyperplasia by propagation of nerve-macrophage interactions in mice.
Enhanced osteointegration of implants in aged rats via a stem cell pool aging reversion strategy.
An intelligent nanoliposome alleviates disc degeneration and discogenic pain by inhibiting neurovascular ingrowth via a "Soil-conditioning, seed-modulating, and weeds-suppressing" strategy.
Role of collagen type III/ITGB1 signalling in stellate cell-mediated regulation of β-cell survival and insulin secretion in the pancreatic islet microenvironment.
The axon initial segment-associated microglia regulate neuronal activity and visual perception.
miRNA‑29a inhibits the proliferation of HUVECs by regulating the ITGB1/β‑catenin/c‑Myc pathway.
HIF-1α/Netrin-4 Axis Mediates RIPC-Induced Angiogenesis and Neurogenesis After Ischemic Stroke.
Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States.
Regulating Integrin β1 to Restore Gonadotropin-Releasing Hormone-Tanycyte Unit Function in Polycystic Ovary Syndrome-Related Hypothalamic Dysregulation.
NRG-1 Promotes Axon Regeneration of Dorsal Root Ganglion Neurons in Diabetic Rats via ITGB1/FAK/AKT Pathway.
MiR-124-3p inhibits proliferation, migration, and epithelial-mesenchymal transformation in gastric cancer by targeting ITGB1.
CD151 Promotes Cancer Progression in Triple-Negative Breast Cancer by Inducing EMT through the MAPK Signaling Pathway.
COL6A2 drives clear cell renal cell carcinoma progression via integrin-dependent modulation of Wnt/β-catenin signaling.
TSPAN15 sustains ITGB1 stability to block gemcitabine-induced ferroptosis in pancreatic ductal adenocarcinoma through the FAK/AKT/Mtor-gpx4 cascade.
Chronic Psychological Stress Induces Cardiomyocyte Hypertrophy Through Corticosterone-Glucocorticoid Receptor-LAMA5 Axis.
Heterogeneity in Osteosarcoma Revealed by scRNA Sequencing: CLU+ Endothelial Cells as Key Players in Tumor Progression.
The hexosamine biosynthetic pathway drives tumor immune evasion via translational control of PD-L1 at the elongation level.
Single-cell multi-omic and spatial profiling of esophageal squamous cell carcinoma reveals the immunosuppressive role of GPR116(+) pericytes in cancer metastasis.
Effect of fibrinogen like protein 1 on cisplatin-resistance in laryngeal carcinoma through targeting integrinβ1 in vivo and in vitro.
Miro1 protects against brain injury after CPR in rats by enhancing the effect of BMSCs on mitochondrial homeostasis.
The CCL20-integrin α5β1 interaction enhances TGF-β/Smad signaling to promote fibroblast activation in pulmonary fibrosis.
High PEEP Activates ITGB1, Inducing Diaphragm Fibrosis During Prolonged Mechanical Ventilation.
Synaptic vesicle protein 2A regulates mossy fiber sprouting in a drug-resistant epilepsy rat model via laminin α5/integrin β1.
Integrin β6 expression in colorectal cancer cells promotes liver metastasis through enhanced adhesion to endothelial fibronectin.
Late embryogenesis abundant protein 3-modified human umbilical cord mesenchymal stem cell sheet exhibits antifreeze properties.
Vitamin D Binding Protein, a Ligand of Integrin beta 1, Motivates Both Tumor Cells and Schwann Cells to Promote Perineural Invasion in Pancreatic Ductal Adenocarcinoma.
Ozone aging amplifies the tumor-promoting effects associated with low-dose graphene oxide exposure in bladder tumors via the integrin αV signaling pathway.
PERK protein kinase facilitates keratinocyte collective cell migration by engagement with cell adhesion molecules, independent of its kinase activity.
NaBC1 Boron Transporter Enables Myoblast Response to Substrate Rigidity via Fibronectin-Binding Integrins.
iTRAQ-based quantitative proteomics reveals dysregulation of fibronectin 1 contributes to impaired endometrial decidualization in recurrent implantation failure.
Deciphering key roles of B cells in prognostication and tailored therapeutic strategies for lung adenocarcinoma: a multi-omics and machine learning approach towards predictive, preventive, and personalized treatment strategies.
Substrate stiffness modulates osteogenic and adipogenic differentiation of osteosarcoma through PIEZO1 mediated signaling pathway.
Excessive MYC Orchestrates Macrophages induced Chromatin Remodeling to Sustain Micropapillary-Patterned Malignancy in Lung Adenocarcinoma.
Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins.
Discovery and Functional Characterization of a Recombinant Fragment of Human Collagen Type XVII.
Enhancing BMSC chondrogenesis with a dynamic viscoelastic hyaluronan hydrogel loaded with kartogenin for cartilage repair.
Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia-Reperfusion Injury.
TNS4 promotes lymph node metastasis of gastric cancer by interacting with integrin Β1 and inducing the activation of fibroblastic reticular cell.
STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma.
Activation of mannose receptor C type 1 in macrophages improves renal fibrosis through mediating fibronectin endocytosis.
Binding of collagen I to integrins alleviates UVB-caused mitochondrial disorders in human keratinocytes HaCaT through enhancement of F-actin polymerization.
Matrix stiffness regulates glucose-6-phosphate dehydrogenase expression to mediate sorafenib resistance in hepatocellular carcinoma through the ITGB1-PI3K/AKT pathway.
The mechanism of Shancigu and its monomer in the development of colorectal cancer based on network pharmacology.
Tumor-intrinsic ENO1 inhibition promotes antitumor immune response and facilitates the efficacy of anti-PD-L1 immunotherapy in bladder cancer.
Monensin suppresses EMT-driven cancer cell motility by inducing Golgi pH-dependent exocytosis of GOLIM4.
Biomimetic Ginsenoside Rb1 and Probucol Co-Assembled Nanoparticles for Targeted Atherosclerosis Therapy via Inhibition of Oxidative Stress, Inflammation, and Lipid Deposition.
Mechanistic insights into the treatment of pulmonary fibrosis with bioactive components from traditional chinese medicine via matrix stiffness-mediated EMT.
Knockdown of integrin β1 inhibits proliferation and promotes apoptosis in bladder cancer cells.
FN1 shapes the behavior of papillary thyroid carcinoma through alternative splicing of EDB region.
Distinct mechanisms of electroacupuncture and manual acupuncture in modulating hypothalamic GnRH-tanycyte unit function of polycystic ovary syndrome.
Mechanistic studies of Ca(2+)-induced classical pyroptosis pathway promoting renal adhesion on calcium oxalate kidney stone formation.
miR-124-3p inhibits CRC proliferation, migration, and invasion by targeting ITGB1.
Lumican from DESC spheroids enhances odontoblastic differentiation of SCAPs.
Microglia-specific interleukin-4 delivery by engineered extracellular vesicles restores inner blood-retinal barrier in diabetic retinopathy via GAS6-MERTK pathway.
Cullin-3 regulates the renal baroreceptor machinery that controls renin gene expression.
NELL2, a novel osteoinductive factor, regulates osteoblast differentiation and bone homeostasis through fibronectin 1/integrin-mediated FAK/AKT signaling.
Macrophage membrane enveloped on double-locked nanoplatform with right-side-out orientation to improving precise theranostic for atherosclerosis.
An Integrated Dual-Layer Heterogeneous Polycaprolactone Scaffold Promotes Oral Mucosal Wound Healing through Inhibiting Bacterial Adhesion and Mediating HGF-1 Behavior.
ITGB1 Alleviates High Glucose-Induced Myocardial Cell Injury by Inhibiting Endoplasmic Reticulum Stress and Cell Apoptosis.
Engagement of α(3)β(1) and α(2)β(1) integrins by hypervirulent Streptococcus agalactiae in invasion of polarized enterocytes.
Dissection of the signal transduction machinery responsible for the lysyl oxidase-like 4-mediated increase in invasive motility in triple-negative breast cancer cells: mechanistic insight into the integrin-β1-NF-κB-MMP9 axis.
Role of integrin β1 and tenascin C mediate TGF-SMAD2/3 signaling in chondrogenic differentiation of BMSCs induced by type I collagen hydrogel.
Ubiquitin-specific peptidase 22 controls integrin-dependent cancer cell stemness and metastasis.
Dissection of the cell communication interactions in lung adenocarcinoma identified a prognostic model with immunotherapy efficacy assessment and a potential therapeutic candidate gene ITGB1.
CREB1 promotes cholangiocarcinoma metastasis through transcriptional regulation of the LAYN-mediated TLN1/β1 integrin axis: CREB1 promotes cholangiocarcinoma metastasis through regulating LAYN/TLN1/β1 integrin axis.
Aberrant serum-derived FN1 variants bind to integrin β1 on glomerular endothelial cells contributing to thin basement membrane nephropathy.
Hepatocyte growth factor promotes melanoma metastasis through ubiquitin-specific peptidase 22-mediated integrins upregulation.
Knockdown of ANO1 decreases TGF-β- and IL-6-induced adhesion and migration of cardiac fibroblasts by inhibiting the expression of integrin and focal adhesion kinase.
Materiobiomodulated ROS Therapy for De Novo Hair Growth.
Mucous cell histopathology and label-free quantitative proteomic analysis of skin mucus in fat greenling (Hexagrammos otakii) infected with Vibrio harveyi.
Effects of the application of low-temperature atmospheric plasma on titanium implants on wound healing in peri-implant connective tissue in rats.
Engineered Surfaces That Promote Capture of Latent Proteins to Facilitate Integrin-Mediated Mechanical Activation of Growth Factors.
A Spatiotemporal Controllable Biomimetic Skin for Accelerating Wound Repair.
Superb Silk Hydrogels with High Adaptability, Bioactivity, and Versatility Enabled by Photo-Cross-Linking.
Echistatin/BYL-719 impedes epithelial-mesenchymal transition in pulmonary fibrosis induced by silica through modulation of the Integrin β1/ILK/PI3K signaling pathway.
Atp6v1h Deficiency Blocks Bone Loss in Simulated Microgravity Mice through the Fos-Jun-Src-Integrin Pathway.
HIF-1A as a prognostic biomarker related to invasion, migration and immunosuppression of cervical cancer.
Cancer-associated fibroblast-derived extracellular vesicles promote lymph node metastases in oral cavity squamous cell carcinoma by encapsulating ITGB1 and BMI1.
hUC-MSCs-derived MFGE8 ameliorates locomotor dysfunction via inhibition of ITGB3/ NF-κB signaling in an NMO mouse model.
DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-α5β1/FAK/AKT signaling.
New TIPARP inhibitor rescues mitochondrial function and brain injury in ischemic stroke.
Tissue factor pathway inhibitor-2 inhibits integrin β1 activation and focal adhesion formation and suppresses peritoneal ovarian cancer dissemination in mice.
Leucine Aminopeptidase LyLAP enables lysosomal degradation of membrane proteins.
Tracing Immunological Interaction in Trimethylamine N-Oxide Hydrogel-Derived Zwitterionic Microenvironment During Promoted Diabetic Wound Regeneration.
Human Umbilical Cord Mesenchymal Stem Cells Repair Endothelial Injury and Dysfunction by Regulating NLRP3 to Inhibit Endothelial Cell Pyroptosis in Kawasaki Disease.
H3K18 lactylation-mediated VCAM1 expression promotes gastric cancer progression and metastasis via AKT-mTOR-CXCL1 axis.
ITGB1-mediated molecular landscape and cuproptosis phenotype induced the worse prognosis in diffuse gastric cancer.
Evaluation of ITGB1 expression as a predictor of the therapeutic effects of immune checkpoint inhibitors in gastric cancer.
Local transplantation of mesenchymal stem cells improves encephalo-myo-synangiosis-mediated collateral neovascularization in chronic brain ischemia.
Progesterone Receptor Membrane Component 1 (PGRMC1) Modulates Tumour Progression, the Immune Microenvironment and the Response to Therapy in Glioblastoma.
Liraglutide intervention improves high-glucose-induced reactive gliosis of Müller cells and ECM dysregulation.
Micronano Titanium Accelerates Mesenchymal Stem Cells Aging through the Activation of Senescence-Associated Secretory Phenotype.
Exploration of 2D and 2.5D Conformational Designs Applied on Epoxide/Collagen-Based Integrative Biointerfaces with Device/Tissue Heterogeneous Affinity.
A Novel Three-Dimensional Follicle Culture System Decreases Oxidative Stress and Promotes the Prolonged Culture of Human Granulosa Cells.
Knockdown of kinesin family member 4A inhibits cell proliferation, migration, and invasion while promoting apoptosis of urothelial bladder carcinoma cells.
γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.
ITGA5 and ITGB1 contribute to Sorafenib resistance by promoting vasculogenic mimicry formation in hepatocellular carcinoma.
Exosomal circTUBGCP4 promotes vascular endothelial cell tipping and colorectal cancer metastasis by activating Akt signaling pathway.
B4GALNT1 promotes hepatocellular carcinoma stemness and progression via integrin α2β1-mediated FAK and AKT activation.
Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway.
The CIS association of CD47 with integrin Mac-1 regulates macrophage responses by stabilizing the extended integrin conformation.
Cyclic Polypeptide D7 Protects Bone Marrow Mesenchymal Cells and Promotes Chondrogenesis during Osteonecrosis of the Femoral Head via Growth Differentiation Factor 15-Mediated Redox Signaling.
Dysregulation of interaction between LOX(high) fibroblast and smooth muscle cells contributes to the pathogenesis of aortic dissection.
p63 Directs Subtype-Specific Gene Expression in HPV+ Head and Neck Squamous Cell Carcinoma.
Dynamic transcriptome changes during osteogenic differentiation of bone marrow-derived mesenchymal stem cells isolated from chicken.
Comparative Study of Traditional Single-Needle Electrospinning and Novel Spiral-Vane Electrospinning: Influence on the Properties of Poly(caprolactone)/Gelatin Nanofiber Membranes.
Single-Cell RNA-Seq Reveals Heterogeneity of Cell Communications between Schwann Cells and Fibroblasts within Vestibular Schwannoma Microenvironment.
A positive mechanobiological feedback loop controls bistable switching of cardiac fibroblast phenotype.
Drebrin promotes lung adenocarcinoma cell migration through inducing integrin β1 endocytosis.
Ultrastructural Characterization of Human Gingival Fibroblasts in 3D Culture.
Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation.
Comprehensive analysis of circRNA-miRNA-mRNA in oral squamous cell carcinoma.
An N-glycoproteomic site-mapping analysis reveals glycoprotein alterations in esophageal squamous cell carcinoma.
Integrin α3β1 promotes vessel formation of glioblastoma-associated endothelial cells through calcium-mediated macropinocytosis and lysosomal exocytosis.
Exosomal miR-455-3p from BMMSCs prevents cardiac ischemia-reperfusion injury.
A novel type of mesenchymal stem cells derived from bovine metanephric mesenchyme.
Mechanosensitive Piezo1 channels mediate renal fibrosis.
Canonical Wnt signaling induces focal adhesion and Integrin beta-1 endocytosis.
Macrophages Cytokine Spp1 Increases Growth of Prostate Intraepithelial Neoplasia to Promote Prostate Tumor Progression.
Mesenchymal Stem Cells With Cancer-Associated Fibroblast-Like Phenotype Stimulate SDF-1/CXCR4 Axis to Enhance the Growth and Invasion of B-Cell Acute Lymphoblastic Leukemia Cells Through Cell-to-Cell Communication.
ITGB1 enhances the Radioresistance of human Non-small Cell Lung Cancer Cells by modulating the DNA damage response and YAP1-induced Epithelial-mesenchymal Transition.
The Overexpression of Acyl-CoA Medium-Chain Synthetase-3 (ACSM3) Suppresses the Ovarian Cancer Progression via the Inhibition of Integrin β1/AKT Signaling Pathway.
P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway.
The Rhinolophus affinis bat ACE2 and multiple animal orthologs are functional receptors for bat coronavirus RaTG13 and SARS-CoV-2.
Iron deficiency promotes aortic medial degeneration via destructing cytoskeleton of vascular smooth muscle cells.
Biomechanically, structurally and functionally meticulously tailored polycaprolactone/silk fibroin scaffold for meniscus regeneration.
Decellularized extracellular matrix scaffolds identify full-length collagen VI as a driver of breast cancer cell invasion in obesity and metastasis.
Modification of PLGA Scaffold by MSC-Derived Extracellular Matrix Combats Macrophage Inflammation to Initiate Bone Regeneration via TGF-β-Induced Protein.
Graphene oxide-coated porous titanium for pulp sealing: an antibacterial and dentino-inductive restorative material.
Exosomes from adipose-derived mesenchymal stem cells prevent cardiomyocyte apoptosis induced by oxidative stress.
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer.
Upregulation of nectin-4 is associated with ITGB1 and vasculogenic mimicry and may serve as a predictor of poor prognosis in colorectal cancer.
Integrin β1 mediates 5-fluorouracil chemoresistance under translational control of eIF4E in colorectal cancer.
Proteomic Analysis of Plasma Membrane Proteins of Antler Stem Cells Using Label-Free LC⁻MS/MS.
Podocyte injury elicits loss and recovery of cellular forces.
Osteogenesis potential of different titania nanotubes in oxidative stress microenvironment.
Polymer Self-Assembled BMSCs with Cancer Tropism and Programmed Homing.
miR-1307-3p suppresses the chondrogenic differentiation of human adipose-derived stem cells by targeting BMPR2.
Annexin A4 fucosylation enhances its interaction with the NF-kB p50 and promotes tumor progression of ovarian clear cell carcinoma.
Micro- and Nanoscale Topographies on Silk Regulate Gene Expression of Human Corneal Epithelial Cells.
Inhibition of peritoneal metastasis of human gastric cancer cells by dextran sulphate through the reduction in HIF-1α and ITGβ1 expression.
Hen egg white ovomacroglobulin promotes fibroblast migration via mediating cell adhesion and cytoskeleton.
Silence of fibronectin 1 increases cisplatin sensitivity of non-small cell lung cancer cell line.
KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway.
17β-Estradiol protects against apoptosis induced by levofloxacin in rat nucleus pulposus cells by upregulating integrin α2β1.
A monoclonal antibody targeting neuropilin-1 inhibits adhesion of MCF7 breast cancer cells to fibronectin by suppressing the FAK/p130cas signaling pathway.
Sine oculis homeobox homolog 1 promotes α5β1-mediated invasive migration and metastasis of cervical cancer cells.
Hu J, Xu Y, Zhou D, Chen K, Jiang J, Lin M, Chen W, Wu J, Jiang H, Zhu M, Zhang B, Xu K, Wei P
Biomaterials research 2026;30:0309
Biomaterials research 2026;30:0309
Endothelial SMAD1-MCAM axis facilitates sunitinib resistance and progression of clear cell renal cell carcinoma via LAMB1-ITGB1 signaling.
Zhang H, Liu Y, Zhang W, Guo Y, Lin A, Jin Y, Lu P, Fang Y, Zhang H, Qu L, Luo P, Wu L, Chen Y, Kang X, Wang L, Jiang A
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101388
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101388
A pH-Responsive Biomimetic Antioxidant Nanoplatform with Dual Renal Targeting for Synergistic Therapy of Acute Kidney Injury.
Zhang S, Xie Y, Zhang L, Qi Y, Liao Q, Xu C, Yang S, Zhou H, Tan Q, Qi S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e15664
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e15664
Tenascin C(+) myofibroblasts exacerbate vascular neointimal hyperplasia by propagation of nerve-macrophage interactions in mice.
Tong X, Shi G, Fang Z, Tang S, Zhou B, Meng Q, Zhang P, Li H, Cai X, Wang Z, Zheng X, Chen W, Jiang G, Wang H, Jiang D, Li Q
Nature communications 2026 Jan 30;17(1)
Nature communications 2026 Jan 30;17(1)
Enhanced osteointegration of implants in aged rats via a stem cell pool aging reversion strategy.
Li X, Luo X, He Y, Zhou B, Xu K, Huang Q, Jiang X, Xiong H, Liu X, Liu S, Tao B, Liu P, Cai K
Biomaterials 2026 Feb;325:123604
Biomaterials 2026 Feb;325:123604
An intelligent nanoliposome alleviates disc degeneration and discogenic pain by inhibiting neurovascular ingrowth via a "Soil-conditioning, seed-modulating, and weeds-suppressing" strategy.
Li F, Shi Y, Liu J, Yang Y, Yan C, Sun X, Zhang Z, Zhang B, Wang Q, Du M, Wang Z, Sun J, Xu X, Sun K, Sun J, Wang Y, Shi J
Bioactive materials 2026 Apr;58:157-182
Bioactive materials 2026 Apr;58:157-182
Role of collagen type III/ITGB1 signalling in stellate cell-mediated regulation of β-cell survival and insulin secretion in the pancreatic islet microenvironment.
Li Q, Zhang X, Wang W, Wang C, Wang B, Li R, Lv Q, Wang J, Liu X, Li L, Zhang Y, Liang J, Persaud SJ, Jones PM, Xu W
Diabetic medicine : a journal of the British Diabetic Association 2026 Apr;43(4):e70260
Diabetic medicine : a journal of the British Diabetic Association 2026 Apr;43(4):e70260
The axon initial segment-associated microglia regulate neuronal activity and visual perception.
Wang Y, Wang Q, Gao C, He S, Wei C, Song J, Liu X, Liu X, Feng S, Yao W, Wu W, Gao TM, Ren S
Cell research 2026 Apr;36(4):249-271
Cell research 2026 Apr;36(4):249-271
miRNA‑29a inhibits the proliferation of HUVECs by regulating the ITGB1/β‑catenin/c‑Myc pathway.
Sun Q, Chen W, Zhang S, Zhong X, Wu Y, Qian Y, Zhu L, Zhang T, Li W
Molecular medicine reports 2026 Apr;33(4)
Molecular medicine reports 2026 Apr;33(4)
HIF-1α/Netrin-4 Axis Mediates RIPC-Induced Angiogenesis and Neurogenesis After Ischemic Stroke.
Feng Z, Liu Z, Tang S, Pan M, Zhu K, Liu Y, Wang C, Yao R, Wei X, Liu H
Journal of cellular and molecular medicine 2026 Apr;30(7):e71121
Journal of cellular and molecular medicine 2026 Apr;30(7):e71121
Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States.
Zhao X, Zheng A, Zhao Z, Li Q, Wan T, Deng T, Zhang Y, Cao L, Wu L
Advanced healthcare materials 2026 Apr;15(13):e04229
Advanced healthcare materials 2026 Apr;15(13):e04229
Regulating Integrin β1 to Restore Gonadotropin-Releasing Hormone-Tanycyte Unit Function in Polycystic Ovary Syndrome-Related Hypothalamic Dysregulation.
Wang Y, Tong X, Xiao Y, Wang Y, Hu W, Lu W, Chen Y, Li J, Gao W, Gao H, Tian Y, Dai S, Feng Y
Research (Washington, D.C.) 2025;8:0619
Research (Washington, D.C.) 2025;8:0619
NRG-1 Promotes Axon Regeneration of Dorsal Root Ganglion Neurons in Diabetic Rats via ITGB1/FAK/AKT Pathway.
Zhan P, Xiong H, Zheng H
International journal of genomics 2025;2025:5520810
International journal of genomics 2025;2025:5520810
MiR-124-3p inhibits proliferation, migration, and epithelial-mesenchymal transformation in gastric cancer by targeting ITGB1.
Li Q, Zhou L, Liang Q, Qin H, Chen Y, Wang T, Wei Q, Luo Y, Li G, Huang H
American journal of translational research 2025;17(4):2500-2512
American journal of translational research 2025;17(4):2500-2512
CD151 Promotes Cancer Progression in Triple-Negative Breast Cancer by Inducing EMT through the MAPK Signaling Pathway.
Lv H, Zhang B, Weng X, Li Y, Deng C, Wang R, Shi L, Yin Y
Breast cancer (Dove Medical Press) 2025;17:455-470
Breast cancer (Dove Medical Press) 2025;17:455-470
COL6A2 drives clear cell renal cell carcinoma progression via integrin-dependent modulation of Wnt/β-catenin signaling.
Ji X, Yun Y, Zhu Z, Wu T, Ruan M, Fan Y, Zhang Q
Journal of Cancer 2025;16(15):4426-4439
Journal of Cancer 2025;16(15):4426-4439
TSPAN15 sustains ITGB1 stability to block gemcitabine-induced ferroptosis in pancreatic ductal adenocarcinoma through the FAK/AKT/Mtor-gpx4 cascade.
Nan P, Wang X, Li A, Ge Y, Gu Z, Wang Y, Tao R
Redox biology 2025 Sep;85:103721
Redox biology 2025 Sep;85:103721
Chronic Psychological Stress Induces Cardiomyocyte Hypertrophy Through Corticosterone-Glucocorticoid Receptor-LAMA5 Axis.
Zhang C, Song Y, Jin X, Xu Q, Ye H, Wu Z, Lin H, Hu J, Huang C, Zhou J, Lian J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e14659
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e14659
Heterogeneity in Osteosarcoma Revealed by scRNA Sequencing: CLU+ Endothelial Cells as Key Players in Tumor Progression.
Dai Z, Xie P, Bai X, Liu T, Guo X, Kuang L, Mu P, Lu F
Cancer science 2025 Sep;116(9):2568-2579
Cancer science 2025 Sep;116(9):2568-2579
The hexosamine biosynthetic pathway drives tumor immune evasion via translational control of PD-L1 at the elongation level.
Liu B, Wu Y, Xiang A, Yu Y, Song S, Zhang Y, Gu J, Lu H, Xu P, Liu F, Ruan Y
Cell reports 2025 Sep 23;44(9):116249
Cell reports 2025 Sep 23;44(9):116249
Single-cell multi-omic and spatial profiling of esophageal squamous cell carcinoma reveals the immunosuppressive role of GPR116(+) pericytes in cancer metastasis.
Pei X, Liu Z, Tang L, Zhang J, He Y, Zhuang X, Song Y, Peng S, He Y, Zhao Y, Huang X, Xu Y, Li J, Peng L, Shi X, Zhang F, Liu C, He M, Dai W, Wu L, Law S, Liu J, Wang Z, Li Z, Xu W, Liu Z, Li B
Nature genetics 2025 Oct;57(10):2494-2508
Nature genetics 2025 Oct;57(10):2494-2508
Effect of fibrinogen like protein 1 on cisplatin-resistance in laryngeal carcinoma through targeting integrinβ1 in vivo and in vitro.
Li Z, Fang J, Ge H, Wang X, Dong H, Yu H, Liu Y, Li T
Discover oncology 2025 Oct 31;16(1):2000
Discover oncology 2025 Oct 31;16(1):2000
Miro1 protects against brain injury after CPR in rats by enhancing the effect of BMSCs on mitochondrial homeostasis.
Ma X, Shen M, Hu J, Zhu J, Wang Z, Zhou Q, Zeng M, Xu M, Qu Y, Zhou X
Stem cell research & therapy 2025 Oct 28;16(1):585
Stem cell research & therapy 2025 Oct 28;16(1):585
The CCL20-integrin α5β1 interaction enhances TGF-β/Smad signaling to promote fibroblast activation in pulmonary fibrosis.
Liu S, Wang Q, Min J, Zhang Z, Zhang Y, Yang J, Tan Y, Tan L, Yin M, Zhang Y, Tang X, Peng H, Xia Z, Xiao Y, Zhou Z, Li X, Liu S
Nature communications 2025 Oct 16;16(1):9183
Nature communications 2025 Oct 16;16(1):9183
High PEEP Activates ITGB1, Inducing Diaphragm Fibrosis During Prolonged Mechanical Ventilation.
Gong J, Jia J, He R, Yu X, Jiang Y, Shen W, Qian X, Xu P, Xu Y, Ge H
Biomolecules 2025 Oct 16;15(10)
Biomolecules 2025 Oct 16;15(10)
Synaptic vesicle protein 2A regulates mossy fiber sprouting in a drug-resistant epilepsy rat model via laminin α5/integrin β1.
Shi Y, Xu Y, Hu Y, Liu L, Li C, Ren S, Wu G, Wang L
Brain research bulletin 2025 Oct 15;231:111536
Brain research bulletin 2025 Oct 15;231:111536
Integrin β6 expression in colorectal cancer cells promotes liver metastasis through enhanced adhesion to endothelial fibronectin.
Passen CV, Krug J, Weiß L, Abdou MM, Tripal P, Schmid B, Krüger R, Lyu Y, Zohud BA, Petter K, Geppert C, Merkel S, Bärthlein B, Busenhart P, Scharl M, Naschberger E, Stürzl M
International journal of cancer 2025 Oct 1;157(7):1481-1495
International journal of cancer 2025 Oct 1;157(7):1481-1495
Late embryogenesis abundant protein 3-modified human umbilical cord mesenchymal stem cell sheet exhibits antifreeze properties.
Guo T, Liu Z, Wang X, Chen J, Wang X, Zhang D
International journal of biological macromolecules 2025 Nov;329(Pt 1):147765
International journal of biological macromolecules 2025 Nov;329(Pt 1):147765
Vitamin D Binding Protein, a Ligand of Integrin beta 1, Motivates Both Tumor Cells and Schwann Cells to Promote Perineural Invasion in Pancreatic Ductal Adenocarcinoma.
Zhang S, Jiang L, Cai S, Weng Z, Zhu Y, Cai ZW, Li H, Li Q, Hu LP, Yao HF, Hua R, Zhao Y, Li D, Yang XM, Zhang JF, Jiang SH
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e11726
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e11726
Ozone aging amplifies the tumor-promoting effects associated with low-dose graphene oxide exposure in bladder tumors via the integrin αV signaling pathway.
Zhu J, Yi B, Ma J, Zhang S, Zhou Z, Qi Y, Qi S
Ecotoxicology and environmental safety 2025 Nov 15;307:119458
Ecotoxicology and environmental safety 2025 Nov 15;307:119458
PERK protein kinase facilitates keratinocyte collective cell migration by engagement with cell adhesion molecules, independent of its kinase activity.
Diaz MB, Staschke KA, Baucum AJ 2nd, Spandau DF, Wek RC
Molecular biology of the cell 2025 Nov 1;36(11):ar40
Molecular biology of the cell 2025 Nov 1;36(11):ar40
NaBC1 Boron Transporter Enables Myoblast Response to Substrate Rigidity via Fibronectin-Binding Integrins.
Gonzalez-Valdivieso J, Ciccone G, Dhawan U, Quon T, Barcelona-Estaje E, Rodrigo-Navarro A, Castillo RR, Milligan G, Rico P, Salmeron-Sanchez M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2407548
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2407548
iTRAQ-based quantitative proteomics reveals dysregulation of fibronectin 1 contributes to impaired endometrial decidualization in recurrent implantation failure.
Wang J, Zhao X, Wu J, Wang C, Wang Q, Fang Y, Yang X
Journal of proteomics 2025 May 30;316:105437
Journal of proteomics 2025 May 30;316:105437
Deciphering key roles of B cells in prognostication and tailored therapeutic strategies for lung adenocarcinoma: a multi-omics and machine learning approach towards predictive, preventive, and personalized treatment strategies.
Zhang J, Hu D, Fang P, Qi M, Sun G
The EPMA journal 2025 Mar;16(1):127-163
The EPMA journal 2025 Mar;16(1):127-163
Substrate stiffness modulates osteogenic and adipogenic differentiation of osteosarcoma through PIEZO1 mediated signaling pathway.
Gao Q, Wang M, Hou X, Li M, Li L
Cellular signalling 2025 Mar;127:111601
Cellular signalling 2025 Mar;127:111601
Excessive MYC Orchestrates Macrophages induced Chromatin Remodeling to Sustain Micropapillary-Patterned Malignancy in Lung Adenocarcinoma.
Song X, Pan Z, Zhang Y, Yang W, Zhang T, Wang H, Chen Y, Yu X, Ding H, Li R, Ge P, Xu L, Dong G, Jiang F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2403851
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2403851
Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins.
Jain A, Heremans I, Rademaker G, Detomasi TC, Rohweder P, Anderson D, Zhang J, Hernandez GA, Gupta S, von Linde T, Lange M, Spacci M, Luo J, Citron YR, Olzmann JA, Dawson DW, Craik CS, Bommer G, Perera RM, Zoncu R
Science (New York, N.Y.) 2025 Mar 28;387(6741):eadq8331
Science (New York, N.Y.) 2025 Mar 28;387(6741):eadq8331
Discovery and Functional Characterization of a Recombinant Fragment of Human Collagen Type XVII.
Piao L, Li J, Li X, Su Y, Yuan X, Chang S, Cheng X, Fu S, Kong R
Journal of agricultural and food chemistry 2025 Mar 19;73(11):6724-6735
Journal of agricultural and food chemistry 2025 Mar 19;73(11):6724-6735
Enhancing BMSC chondrogenesis with a dynamic viscoelastic hyaluronan hydrogel loaded with kartogenin for cartilage repair.
Li G, Ni R, Shi Z, Mao H, Luo Y, Cao X, Zhang C, Liu Y, Jin Z, Chen J, Fu J, Zhang H, Zhu Y
International journal of biological macromolecules 2025 Jun;312:144042
International journal of biological macromolecules 2025 Jun;312:144042
Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia-Reperfusion Injury.
Cheng N, Luo Q, Yang Y, Shao N, Nie T, Deng X, Chen J, Zhang S, Huang Y, Hu K, Luo L, Xiao Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(24):e2410590
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(24):e2410590
TNS4 promotes lymph node metastasis of gastric cancer by interacting with integrin Β1 and inducing the activation of fibroblastic reticular cell.
Zhang X, Su GH, Bao TS, He WP, Wang YY, Zhou YQ, Xie JX, Wang F, Lu R, Zhang S, Yi SQ, Li Q, Jiang SH, Li H, Hu LP, Li J, Xu J
Cancer cell international 2025 Jun 6;25(1):204
Cancer cell international 2025 Jun 6;25(1):204
STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma.
Yu W, Gui S, Peng L, Luo H, Xie J, Xiao J, Yilamu Y, Sun Y, Cai S, Cheng Z, Tao Z
Developmental cell 2025 Jun 23;60(12):1751-1767.e9
Developmental cell 2025 Jun 23;60(12):1751-1767.e9
Activation of mannose receptor C type 1 in macrophages improves renal fibrosis through mediating fibronectin endocytosis.
Long L, Li M, Wang M, Liang B, Huang M, Yuan X, Wu X, Guo X, Li S, Liu Z, Liu W, Chen W, Wang W, Lyu Q, Li C
Life sciences 2025 Jun 15;371:123593
Life sciences 2025 Jun 15;371:123593
Binding of collagen I to integrins alleviates UVB-caused mitochondrial disorders in human keratinocytes HaCaT through enhancement of F-actin polymerization.
Zhu Y, Ji T, San Z, Cao R, Hayashi T, Mizuno K, Hattori S, Fujisaki H, Liu W, Ikejima T
Journal of photochemistry and photobiology. B, Biology 2025 Jul;268:113170
Journal of photochemistry and photobiology. B, Biology 2025 Jul;268:113170
Matrix stiffness regulates glucose-6-phosphate dehydrogenase expression to mediate sorafenib resistance in hepatocellular carcinoma through the ITGB1-PI3K/AKT pathway.
Ren R, Zhang S, Peng Z, Ji X, Song H, Wang Q, Sun X, Wang H, Dong Y
Cell death & disease 2025 Jul 20;16(1):538
Cell death & disease 2025 Jul 20;16(1):538
The mechanism of Shancigu and its monomer in the development of colorectal cancer based on network pharmacology.
Li G, Zhu X, Zhao R, Zhang X, Huang C, Shu M, Liu L, Yuan J
Scientific reports 2025 Jul 2;15(1):23186
Scientific reports 2025 Jul 2;15(1):23186
Tumor-intrinsic ENO1 inhibition promotes antitumor immune response and facilitates the efficacy of anti-PD-L1 immunotherapy in bladder cancer.
Shen C, Liu J, Hu D, Liu C, Xie F, Wang Y
Journal of experimental & clinical cancer research : CR 2025 Jul 15;44(1):207
Journal of experimental & clinical cancer research : CR 2025 Jul 15;44(1):207
Monensin suppresses EMT-driven cancer cell motility by inducing Golgi pH-dependent exocytosis of GOLIM4.
Tan X, Cardin DL, Wang S, Xu Y, Russell WK
Proceedings of the National Academy of Sciences of the United States of America 2025 Jul 15;122(28):e2501347122
Proceedings of the National Academy of Sciences of the United States of America 2025 Jul 15;122(28):e2501347122
Biomimetic Ginsenoside Rb1 and Probucol Co-Assembled Nanoparticles for Targeted Atherosclerosis Therapy via Inhibition of Oxidative Stress, Inflammation, and Lipid Deposition.
Zeng J, Zhang Y, Gao Y, Jia M, Guo Y, Li X, Wang Y, Zhao C, Qiu J, McGinty S, Miao W, Wang G, Wang Y
ACS nano 2025 Jul 1;19(25):22968-22987
ACS nano 2025 Jul 1;19(25):22968-22987
Mechanistic insights into the treatment of pulmonary fibrosis with bioactive components from traditional chinese medicine via matrix stiffness-mediated EMT.
Li K, Liu H, Li M, Sun M, Peng X, Wu Y, Tian Y, Liu X, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156266
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156266
Knockdown of integrin β1 inhibits proliferation and promotes apoptosis in bladder cancer cells.
Wang JF, Wang JS, Liu Y, Ji B, Ding BC, Wang YX, Ren MH
BioFactors (Oxford, England) 2025 Jan-Feb;51(1):e2150
BioFactors (Oxford, England) 2025 Jan-Feb;51(1):e2150
FN1 shapes the behavior of papillary thyroid carcinoma through alternative splicing of EDB region.
Liu M, Chen P, Wei B, Tan HL, Zhao YX, Ai L, Li N, Jiang YK, Lin J, Li SJ, Chang S
Scientific reports 2025 Jan 2;15(1):327
Scientific reports 2025 Jan 2;15(1):327
Distinct mechanisms of electroacupuncture and manual acupuncture in modulating hypothalamic GnRH-tanycyte unit function of polycystic ovary syndrome.
Wang Y, Wang Y, Chen Y, Lu W, Tong X, Li J, Gao W, Huang R, Hu W, Feng Y
Chinese medicine 2025 Feb 5;20(1):18
Chinese medicine 2025 Feb 5;20(1):18
Mechanistic studies of Ca(2+)-induced classical pyroptosis pathway promoting renal adhesion on calcium oxalate kidney stone formation.
Xiang J, Lv M, Luo Y, Ke K, Zhang B, Wang M, Zhang K, Li H
Scientific reports 2025 Feb 24;15(1):6669
Scientific reports 2025 Feb 24;15(1):6669
miR-124-3p inhibits CRC proliferation, migration, and invasion by targeting ITGB1.
Li J, Liu L
Discover oncology 2025 Feb 11;16(1):158
Discover oncology 2025 Feb 11;16(1):158
Lumican from DESC spheroids enhances odontoblastic differentiation of SCAPs.
Zhang Q, Huang S, Liu X, Zhang M, Sun J, Liu M, Nie H, Lei L
Stem cell research & therapy 2025 Dec 7;17(1):27
Stem cell research & therapy 2025 Dec 7;17(1):27
Microglia-specific interleukin-4 delivery by engineered extracellular vesicles restores inner blood-retinal barrier in diabetic retinopathy via GAS6-MERTK pathway.
Fan Y, Ge P, Wang X, Xu J, Wang J, Li H, Gu Q, Xie H, Lin Y, Lu Y, Wang C, Xie P, Hu Z
Journal of nanobiotechnology 2025 Dec 29;24(1):101
Journal of nanobiotechnology 2025 Dec 29;24(1):101
Cullin-3 regulates the renal baroreceptor machinery that controls renin gene expression.
Golosova D, Kumar G, Lu KT, Muskus Veitia PC, Hantke Guixa A, Wackman KK, Fekete EM, Brozoski DT, Grobe JL, Sequeira-Lopez MLS, Gomez RA, Nakagawa P, Sigmund CD
JCI insight 2025 Aug 8;10(15)
JCI insight 2025 Aug 8;10(15)
NELL2, a novel osteoinductive factor, regulates osteoblast differentiation and bone homeostasis through fibronectin 1/integrin-mediated FAK/AKT signaling.
Yuan H, Wang X, Du S, Li M, Zhu E, Zhou J, Dong Y, Wang S, Shan L, Liu Q, Wang B
Bone research 2025 Apr 11;13(1):46
Bone research 2025 Apr 11;13(1):46
Macrophage membrane enveloped on double-locked nanoplatform with right-side-out orientation to improving precise theranostic for atherosclerosis.
Liu J, He Z, Qin X, Zhang K, Qu K, Zhong Y, Yang W, Wu W
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:800-817
Journal of controlled release : official journal of the Controlled Release Society 2025 Apr 10;380:800-817
An Integrated Dual-Layer Heterogeneous Polycaprolactone Scaffold Promotes Oral Mucosal Wound Healing through Inhibiting Bacterial Adhesion and Mediating HGF-1 Behavior.
Hong G, Hu Z, Zhou Y, Chen M, Wu H, Lu W, Jin W, Yao K, Xie Z, Shi J
Research (Washington, D.C.) 2024;7:0499
Research (Washington, D.C.) 2024;7:0499
ITGB1 Alleviates High Glucose-Induced Myocardial Cell Injury by Inhibiting Endoplasmic Reticulum Stress and Cell Apoptosis.
Cheng C, Li J, Zhang D, Xu D, Yu W
International heart journal 2024;65(6):1137-1143
International heart journal 2024;65(6):1137-1143
Engagement of α(3)β(1) and α(2)β(1) integrins by hypervirulent Streptococcus agalactiae in invasion of polarized enterocytes.
De Gaetano GV, Lentini G, Coppolino F, Famà A, Pietrocola G, Beninati C
Frontiers in microbiology 2024;15:1367898
Frontiers in microbiology 2024;15:1367898
Dissection of the signal transduction machinery responsible for the lysyl oxidase-like 4-mediated increase in invasive motility in triple-negative breast cancer cells: mechanistic insight into the integrin-β1-NF-κB-MMP9 axis.
Jiang F, Chen Y, Tomonobu N, Kinoshita R, Komalasari NLGY, Kasano-Camones CI, Ninomiya K, Murata H, Yamamoto KI, Gohara Y, Ochi T, Ruma IMW, Sumardika IW, Zhou J, Honjo T, Sakaguchi Y, Yamauchi A, Kuribayashi F, Futami J, Kondo E, Inoue Y, Toyooka S, Sakaguchi M
Frontiers in oncology 2024;14:1371307
Frontiers in oncology 2024;14:1371307
Role of integrin β1 and tenascin C mediate TGF-SMAD2/3 signaling in chondrogenic differentiation of BMSCs induced by type I collagen hydrogel.
Huang Y, Sun M, Lu Z, Zhong Q, Tan M, Wei Q, Zheng L
Regenerative biomaterials 2024;11:rbae017
Regenerative biomaterials 2024;11:rbae017
Ubiquitin-specific peptidase 22 controls integrin-dependent cancer cell stemness and metastasis.
Liu K, Gao Q, Jia Y, Wei J, Chaudhuri SM, Wang S, Tang A, Mani NL, Iyer R, Cheng Y, Gao B, Lu W, Sun Z, Zhang B, Liu H, Fang D
iScience 2024 Sep 20;27(9):110592
iScience 2024 Sep 20;27(9):110592
Dissection of the cell communication interactions in lung adenocarcinoma identified a prognostic model with immunotherapy efficacy assessment and a potential therapeutic candidate gene ITGB1.
Jin X, Hu Z, Yin J, Shan G, Zhao M, Liao Z, Liang J, Bi G, Cheng Y, Xi J, Chen Z, Lin M
Heliyon 2024 Sep 15;10(17):e36599
Heliyon 2024 Sep 15;10(17):e36599
CREB1 promotes cholangiocarcinoma metastasis through transcriptional regulation of the LAYN-mediated TLN1/β1 integrin axis: CREB1 promotes cholangiocarcinoma metastasis through regulating LAYN/TLN1/β1 integrin axis.
Liang S, Zhou S, Tang Y, Xiao M, Ye K
Heliyon 2024 Sep 15;10(17):e36595
Heliyon 2024 Sep 15;10(17):e36595
Aberrant serum-derived FN1 variants bind to integrin β1 on glomerular endothelial cells contributing to thin basement membrane nephropathy.
Zhou X, Chen W, Gan C, Chen D, Xiao H, Jiang Y, Yang Q, Jiang H, Yang X, Yang B, Chen Y, Wang M, Yang H, Jiang W, Li Q
International journal of biological macromolecules 2024 Nov;281(Pt 1):136282
International journal of biological macromolecules 2024 Nov;281(Pt 1):136282
Hepatocyte growth factor promotes melanoma metastasis through ubiquitin-specific peptidase 22-mediated integrins upregulation.
Gao Q, Li N, Pan Y, Chu P, Zhou Y, Jia H, Cheng Y, Xue G, Song J, Zhang Y, Zhu H, Sun J, Zhang B, Sun Z, Fang D
Cancer letters 2024 Nov 1;604:217196
Cancer letters 2024 Nov 1;604:217196
Knockdown of ANO1 decreases TGF-β- and IL-6-induced adhesion and migration of cardiac fibroblasts by inhibiting the expression of integrin and focal adhesion kinase.
Tian X, Zhang Y, Gong H, Bai M, Sun C, Jia Y, Duan C, Wang X
Experimental cell research 2024 Nov 1;443(1):114321
Experimental cell research 2024 Nov 1;443(1):114321
Materiobiomodulated ROS Therapy for De Novo Hair Growth.
Bai L, Wang Y, Wang K, Chen X, Zhao Y, Liu C, Qu X
Advanced materials (Deerfield Beach, Fla.) 2024 May;36(21):e2311459
Advanced materials (Deerfield Beach, Fla.) 2024 May;36(21):e2311459
Mucous cell histopathology and label-free quantitative proteomic analysis of skin mucus in fat greenling (Hexagrammos otakii) infected with Vibrio harveyi.
Wei X, Shi Y, Wang S, Liu H, Zhang Z, Yu L, Hua W, Cui D, Chen Y, Li X, Wang W
Fish & shellfish immunology 2024 Mar;146:109398
Fish & shellfish immunology 2024 Mar;146:109398
Effects of the application of low-temperature atmospheric plasma on titanium implants on wound healing in peri-implant connective tissue in rats.
Harada A, Sasaki H, Asami Y, Hanazawa K, Miyazaki S, Sekine H, Yajima Y
International journal of implant dentistry 2024 Mar 21;10(1):15
International journal of implant dentistry 2024 Mar 21;10(1):15
Engineered Surfaces That Promote Capture of Latent Proteins to Facilitate Integrin-Mediated Mechanical Activation of Growth Factors.
Dhawan U, Williams JA, Windmill JFC, Childs P, Gonzalez-Garcia C, Dalby MJ, Salmeron-Sanchez M
Advanced materials (Deerfield Beach, Fla.) 2024 Jun;36(23):e2310789
Advanced materials (Deerfield Beach, Fla.) 2024 Jun;36(23):e2310789
A Spatiotemporal Controllable Biomimetic Skin for Accelerating Wound Repair.
Chen Y, Lu W, Zhou Y, Hu Z, Wu H, Gao Q, Shi J, Wu W, Lv S, Yao K, He Y, Xie Z
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(23):e2310556
Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(23):e2310556
Superb Silk Hydrogels with High Adaptability, Bioactivity, and Versatility Enabled by Photo-Cross-Linking.
Huang R, Hua J, Ru M, Yu M, Wang L, Huang Y, Yan S, Zhang Q, Xu W
ACS nano 2024 Jun 11;18(23):15312-15325
ACS nano 2024 Jun 11;18(23):15312-15325
Echistatin/BYL-719 impedes epithelial-mesenchymal transition in pulmonary fibrosis induced by silica through modulation of the Integrin β1/ILK/PI3K signaling pathway.
Li H, Wang P, Hu M, Xu S, Li X, Xu D, Feng K, Zhou Q, Chang M, Yao S
International immunopharmacology 2024 Jul 30;136:112368
International immunopharmacology 2024 Jul 30;136:112368
Atp6v1h Deficiency Blocks Bone Loss in Simulated Microgravity Mice through the Fos-Jun-Src-Integrin Pathway.
Zhao Z, Wang X, Ma Y, Duan X
International journal of molecular sciences 2024 Jan 4;25(1)
International journal of molecular sciences 2024 Jan 4;25(1)
HIF-1A as a prognostic biomarker related to invasion, migration and immunosuppression of cervical cancer.
Li Z, Wei R, Yao S, Meng F, Kong L
Heliyon 2024 Jan 30;10(2):e24664
Heliyon 2024 Jan 30;10(2):e24664
Cancer-associated fibroblast-derived extracellular vesicles promote lymph node metastases in oral cavity squamous cell carcinoma by encapsulating ITGB1 and BMI1.
Lv T, Liu H, Mao L, Song Y, Liao L, Zhong K, Shuai B, Luo Y, Guo T, Huang W, Zhang S
BMC cancer 2024 Jan 22;24(1):113
BMC cancer 2024 Jan 22;24(1):113
hUC-MSCs-derived MFGE8 ameliorates locomotor dysfunction via inhibition of ITGB3/ NF-κB signaling in an NMO mouse model.
Xu H, Jiang W, Li X, Jiang J, Afridi SK, Deng L, Li R, Luo E, Zhang Z, Huang YA, Cui Y, So KF, Chen H, Qiu W, Tang C
NPJ Regenerative medicine 2024 Jan 20;9(1):4
NPJ Regenerative medicine 2024 Jan 20;9(1):4
DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-α5β1/FAK/AKT signaling.
Liu C, Xu J, Fan J, Liu C, Xie W, Kong H
Experimental cell research 2024 Feb 1;435(1):113909
Experimental cell research 2024 Feb 1;435(1):113909
New TIPARP inhibitor rescues mitochondrial function and brain injury in ischemic stroke.
Cai Y, Gu H, Li L, Liu X, Bai Y, Shen L, Han B, Xu Y, Yao H
Pharmacological research 2024 Dec;210:107508
Pharmacological research 2024 Dec;210:107508
Tissue factor pathway inhibitor-2 inhibits integrin β1 activation and focal adhesion formation and suppresses peritoneal ovarian cancer dissemination in mice.
Ota Y, Uomoto M, Koizume S, Sato S, Hoshino D, Yoshihara M, Nakamura Y, Tadokoro H, Myoba S, Ohtake N, Miyagi E, Miyagi Y
Biochemical and biophysical research communications 2024 Dec 3;736:150890
Biochemical and biophysical research communications 2024 Dec 3;736:150890
Leucine Aminopeptidase LyLAP enables lysosomal degradation of membrane proteins.
Jain A, Heremans I, Rademaker G, Detomasi TC, Hernandez GA, Zhang J, Gupta S, von Linde T, Lange M, Spacci M, Rohweder P, Anderson D, Citron YR, Olzmann JA, Dawson DW, Craik CS, Bommer G, Perera RM, Zoncu R
bioRxiv : the preprint server for biology 2024 Dec 14;
bioRxiv : the preprint server for biology 2024 Dec 14;
Tracing Immunological Interaction in Trimethylamine N-Oxide Hydrogel-Derived Zwitterionic Microenvironment During Promoted Diabetic Wound Regeneration.
Li Z, Li L, Yue M, Peng Q, Pu X, Zhou Y
Advanced materials (Deerfield Beach, Fla.) 2024 Aug;36(33):e2402738
Advanced materials (Deerfield Beach, Fla.) 2024 Aug;36(33):e2402738
Human Umbilical Cord Mesenchymal Stem Cells Repair Endothelial Injury and Dysfunction by Regulating NLRP3 to Inhibit Endothelial Cell Pyroptosis in Kawasaki Disease.
Xu T, Chen T, Fang H, Shen X, Shen X, Tang Z, Zhao J
Inflammation 2024 Apr;47(2):483-502
Inflammation 2024 Apr;47(2):483-502
H3K18 lactylation-mediated VCAM1 expression promotes gastric cancer progression and metastasis via AKT-mTOR-CXCL1 axis.
Zhao Y, Jiang J, Zhou P, Deng K, Liu Z, Yang M, Yang X, Li J, Li R, Xia J
Biochemical pharmacology 2024 Apr;222:116120
Biochemical pharmacology 2024 Apr;222:116120
ITGB1-mediated molecular landscape and cuproptosis phenotype induced the worse prognosis in diffuse gastric cancer.
Zhu X, Chen H, Li H, Ren H, Ye C, Xu K, Liu J, Du F, Zhang Z, Liu Y, Xie X, Wang M, Ma T, Chong W, Shang L, Li L
Frontiers in oncology 2023;13:1115510
Frontiers in oncology 2023;13:1115510
Evaluation of ITGB1 expression as a predictor of the therapeutic effects of immune checkpoint inhibitors in gastric cancer.
Xu C, Xie XL, Kang N, Jiang HQ
BMC gastroenterology 2023 Sep 4;23(1):298
BMC gastroenterology 2023 Sep 4;23(1):298
Local transplantation of mesenchymal stem cells improves encephalo-myo-synangiosis-mediated collateral neovascularization in chronic brain ischemia.
Zhang X, Huang Y, Liu Y, Liu Y, He X, Ma X, Gan C, Zou X, Wang S, Shu K, Lei T, Zhang H
Stem cell research & therapy 2023 Sep 4;14(1):233
Stem cell research & therapy 2023 Sep 4;14(1):233
Progesterone Receptor Membrane Component 1 (PGRMC1) Modulates Tumour Progression, the Immune Microenvironment and the Response to Therapy in Glioblastoma.
Dumitru CA, Schröder H, Schäfer FTA, Aust JF, Kreße N, Siebert CLR, Stein KP, Haghikia A, Wilkens L, Mawrin C, Sandalcioglu IE
Cells 2023 Oct 20;12(20)
Cells 2023 Oct 20;12(20)
Liraglutide intervention improves high-glucose-induced reactive gliosis of Müller cells and ECM dysregulation.
Shan Y, Gao X, Zhao K, Xu C, Li H, Hu Y, Lin W, Ma X, Xu Q, Kuang H, Hao M
Molecular and cellular endocrinology 2023 Oct 1;576:112013
Molecular and cellular endocrinology 2023 Oct 1;576:112013
Micronano Titanium Accelerates Mesenchymal Stem Cells Aging through the Activation of Senescence-Associated Secretory Phenotype.
Li X, Luo X, He Y, Xu K, Ding Y, Gao P, Tao B, Li M, Tan M, Liu S, Liu P, Cai K
ACS nano 2023 Nov 28;17(22):22885-22900
ACS nano 2023 Nov 28;17(22):22885-22900
Exploration of 2D and 2.5D Conformational Designs Applied on Epoxide/Collagen-Based Integrative Biointerfaces with Device/Tissue Heterogeneous Affinity.
Zhang Y, Yang C, Yin S, Zhang X, Peng X, Li G
ACS applied materials & interfaces 2023 May 17;15(19):22876-22891
ACS applied materials & interfaces 2023 May 17;15(19):22876-22891
A Novel Three-Dimensional Follicle Culture System Decreases Oxidative Stress and Promotes the Prolonged Culture of Human Granulosa Cells.
Zhao X, Zhang S, Gao S, Chang HM, Leung PCK, Tan J
ACS applied materials & interfaces 2023 Mar 29;15(12):15084-15095
ACS applied materials & interfaces 2023 Mar 29;15(12):15084-15095
Knockdown of kinesin family member 4A inhibits cell proliferation, migration, and invasion while promoting apoptosis of urothelial bladder carcinoma cells.
Zhang C, Wang M, Ying Y, Meng F, Gao H, Zeng S, Zhu Y, Liu A, Zhang Z, Xu C
Cancer medicine 2023 Jun;12(11):12581-12592
Cancer medicine 2023 Jun;12(11):12581-12592
γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.
Chen W, Yu H, Sun C, Dong M, Zhao N, Wang Y, Yu K, Zhang J, Xu N, Liu W
Toxicology letters 2023 Jul 1;383:177-191
Toxicology letters 2023 Jul 1;383:177-191
ITGA5 and ITGB1 contribute to Sorafenib resistance by promoting vasculogenic mimicry formation in hepatocellular carcinoma.
Shi Y, Shang J, Li Y, Zhong D, Zhang Z, Yang Q, Lai C, Feng T, Yao Y, Huang X
Cancer medicine 2023 Feb;12(3):3786-3796
Cancer medicine 2023 Feb;12(3):3786-3796
Exosomal circTUBGCP4 promotes vascular endothelial cell tipping and colorectal cancer metastasis by activating Akt signaling pathway.
Chen C, Liu Y, Liu L, Si C, Xu Y, Wu X, Wang C, Sun Z, Kang Q
Journal of experimental & clinical cancer research : CR 2023 Feb 15;42(1):46
Journal of experimental & clinical cancer research : CR 2023 Feb 15;42(1):46
B4GALNT1 promotes hepatocellular carcinoma stemness and progression via integrin α2β1-mediated FAK and AKT activation.
Tang Y, Xu Z, Xu F, Ye J, Chen J, He J, Chen Y, Qi C, Huang H, Liu R, Shan H, Xiao F
JHEP reports : innovation in hepatology 2023 Dec;5(12):100903
JHEP reports : innovation in hepatology 2023 Dec;5(12):100903
Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway.
Zhang B, Li X, Zhou X, Lou C, Wang S, Lv H, Zhang G, Fang Y, Yin D, Shang P
iScience 2023 Aug 18;26(8):107365
iScience 2023 Aug 18;26(8):107365
The CIS association of CD47 with integrin Mac-1 regulates macrophage responses by stabilizing the extended integrin conformation.
Podolnikova NP, Key S, Wang X, Ugarova TP
The Journal of biological chemistry 2023 Apr;299(4):103024
The Journal of biological chemistry 2023 Apr;299(4):103024
Cyclic Polypeptide D7 Protects Bone Marrow Mesenchymal Cells and Promotes Chondrogenesis during Osteonecrosis of the Femoral Head via Growth Differentiation Factor 15-Mediated Redox Signaling.
Chen J, Cui Z, Wang Y, Lyu L, Feng C, Feng D, Cheng Y, Li Z, Sun S
Oxidative medicine and cellular longevity 2022;2022:3182368
Oxidative medicine and cellular longevity 2022;2022:3182368
Dysregulation of interaction between LOX(high) fibroblast and smooth muscle cells contributes to the pathogenesis of aortic dissection.
Chen Y, Zhang T, Yao F, Gao X, Li D, Fu S, Mao L, Liu F, Zhang X, Xu Y, Deng J, Li W, Fan G, Xiao C, Chen Y, Wang L, Guo W, Zhou B
Theranostics 2022;12(2):910-928
Theranostics 2022;12(2):910-928
p63 Directs Subtype-Specific Gene Expression in HPV+ Head and Neck Squamous Cell Carcinoma.
Glathar AR, Oyelakin A, Gluck C, Bard J, Sinha S
Frontiers in oncology 2022;12:879054
Frontiers in oncology 2022;12:879054
Dynamic transcriptome changes during osteogenic differentiation of bone marrow-derived mesenchymal stem cells isolated from chicken.
Lv H, Wang T, Zhai S, Hou Z, Chen S
Frontiers in cell and developmental biology 2022;10:940248
Frontiers in cell and developmental biology 2022;10:940248
Comparative Study of Traditional Single-Needle Electrospinning and Novel Spiral-Vane Electrospinning: Influence on the Properties of Poly(caprolactone)/Gelatin Nanofiber Membranes.
Xu Q, Liu W, Yi B
Frontiers in bioengineering and biotechnology 2022;10:847800
Frontiers in bioengineering and biotechnology 2022;10:847800
Single-Cell RNA-Seq Reveals Heterogeneity of Cell Communications between Schwann Cells and Fibroblasts within Vestibular Schwannoma Microenvironment.
Xu M, Wang S, Jiang Y, Wang J, Xiong Y, Dong W, Yao Q, Xing Y, Liu F, Chen Z, Yu D
The American journal of pathology 2022 Sep;192(9):1230-1249
The American journal of pathology 2022 Sep;192(9):1230-1249
A positive mechanobiological feedback loop controls bistable switching of cardiac fibroblast phenotype.
Niu L, Cheng B, Huang G, Nan K, Han S, Ren H, Liu N, Li Y, Genin GM, Xu F
Cell discovery 2022 Sep 6;8(1):84
Cell discovery 2022 Sep 6;8(1):84
Drebrin promotes lung adenocarcinoma cell migration through inducing integrin β1 endocytosis.
Yu Q, Tang F, Cao F, Tan X, Weng L, Sun L
Biochemical and biophysical research communications 2022 Nov 19;630:175-182
Biochemical and biophysical research communications 2022 Nov 19;630:175-182
Ultrastructural Characterization of Human Gingival Fibroblasts in 3D Culture.
Alfonso García SL, Mira Uribe LM, Castaño López S, Parada-Sanchez MT, Arboleda-Toro D
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Integrin beta-1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Integrin beta-1. This antibody recognizes human,mouse,rat antigen. The Integrin beta-1 antibody has been validated for the following applications: ELISA, WB analysis.
