Antibody data
- Antibody Data
- Antigen structure
- References [25]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 12594-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12594-1-AP, RRID:AB_2130085
- Product name
- Integrin Beta 1 antibody
- Antibody type
- Polyclonal
- Description
- Integrin Beta 1 antibody (Cat. #12594-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ITGB1 enhances the Radioresistance of human Non-small Cell Lung Cancer Cells by modulating the DNA damage response and YAP1-induced Epithelial-mesenchymal Transition.
The Overexpression of Acyl-CoA Medium-Chain Synthetase-3 (ACSM3) Suppresses the Ovarian Cancer Progression via the Inhibition of Integrin β1/AKT Signaling Pathway.
P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway.
The Rhinolophus affinis bat ACE2 and multiple animal orthologs are functional receptors for bat coronavirus RaTG13 and SARS-CoV-2.
Iron deficiency promotes aortic medial degeneration via destructing cytoskeleton of vascular smooth muscle cells.
Biomechanically, structurally and functionally meticulously tailored polycaprolactone/silk fibroin scaffold for meniscus regeneration.
Decellularized extracellular matrix scaffolds identify full-length collagen VI as a driver of breast cancer cell invasion in obesity and metastasis.
Modification of PLGA Scaffold by MSC-Derived Extracellular Matrix Combats Macrophage Inflammation to Initiate Bone Regeneration via TGF-β-Induced Protein.
Graphene oxide-coated porous titanium for pulp sealing: an antibacterial and dentino-inductive restorative material.
Exosomes from adipose-derived mesenchymal stem cells prevent cardiomyocyte apoptosis induced by oxidative stress.
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer.
Upregulation of nectin-4 is associated with ITGB1 and vasculogenic mimicry and may serve as a predictor of poor prognosis in colorectal cancer.
Proteomic Analysis of Plasma Membrane Proteins of Antler Stem Cells Using Label-Free LC⁻MS/MS.
Podocyte injury elicits loss and recovery of cellular forces.
Osteogenesis potential of different titania nanotubes in oxidative stress microenvironment.
Polymer Self-Assembled BMSCs with Cancer Tropism and Programmed Homing.
Annexin A4 fucosylation enhances its interaction with the NF-kB p50 and promotes tumor progression of ovarian clear cell carcinoma.
Micro- and Nanoscale Topographies on Silk Regulate Gene Expression of Human Corneal Epithelial Cells.
Inhibition of peritoneal metastasis of human gastric cancer cells by dextran sulphate through the reduction in HIF-1α and ITGβ1 expression.
Hen egg white ovomacroglobulin promotes fibroblast migration via mediating cell adhesion and cytoskeleton.
Silence of fibronectin 1 increases cisplatin sensitivity of non-small cell lung cancer cell line.
KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway.
17β-Estradiol protects against apoptosis induced by levofloxacin in rat nucleus pulposus cells by upregulating integrin α2β1.
A monoclonal antibody targeting neuropilin-1 inhibits adhesion of MCF7 breast cancer cells to fibronectin by suppressing the FAK/p130cas signaling pathway.
Sine oculis homeobox homolog 1 promotes α5β1-mediated invasive migration and metastasis of cervical cancer cells.
Li Y, Sun C, Tan Y, Zhang H, Li Y, Zou H
International journal of biological sciences 2021;17(2):635-650
International journal of biological sciences 2021;17(2):635-650
The Overexpression of Acyl-CoA Medium-Chain Synthetase-3 (ACSM3) Suppresses the Ovarian Cancer Progression via the Inhibition of Integrin β1/AKT Signaling Pathway.
Yan L, He Z, Li W, Liu N, Gao S
Frontiers in oncology 2021;11:644840
Frontiers in oncology 2021;11:644840
P76RBE silencing inhibits ovarian cancer cell proliferation, migration, and invasion via suppressing the integrin β1/NF-κB pathway.
Yan L, He Z, Li W, Liu N, Gao S
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1875-1889
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1875-1889
The Rhinolophus affinis bat ACE2 and multiple animal orthologs are functional receptors for bat coronavirus RaTG13 and SARS-CoV-2.
Li P, Guo R, Liu Y, Zhang Y, Hu J, Ou X, Mi D, Chen T, Mu Z, Han Y, Chen Z, Cui Z, Zhang L, Wang X, Wu Z, Wang J, Jin Q, Qian Z
Science bulletin 2021 Jun 30;66(12):1215-1227
Science bulletin 2021 Jun 30;66(12):1215-1227
Iron deficiency promotes aortic medial degeneration via destructing cytoskeleton of vascular smooth muscle cells.
Li B, Wang Z, Hong J, Che Y, Chen R, Hu Z, Hu X, Wu Q, Hu J, Zhang M
Clinical and translational medicine 2021 Jan;11(1):e276
Clinical and translational medicine 2021 Jan;11(1):e276
Biomechanically, structurally and functionally meticulously tailored polycaprolactone/silk fibroin scaffold for meniscus regeneration.
Li Z, Wu N, Cheng J, Sun M, Yang P, Zhao F, Zhang J, Duan X, Fu X, Zhang J, Hu X, Chen H, Ao Y
Theranostics 2020;10(11):5090-5106
Theranostics 2020;10(11):5090-5106
Decellularized extracellular matrix scaffolds identify full-length collagen VI as a driver of breast cancer cell invasion in obesity and metastasis.
Wishart AL, Conner SJ, Guarin JR, Fatherree JP, Peng Y, McGinn RA, Crews R, Naber SP, Hunter M, Greenberg AS, Oudin MJ
Science advances 2020 Oct;6(43)
Science advances 2020 Oct;6(43)
Modification of PLGA Scaffold by MSC-Derived Extracellular Matrix Combats Macrophage Inflammation to Initiate Bone Regeneration via TGF-β-Induced Protein.
Deng M, Tan J, Hu C, Hou T, Peng W, Liu J, Yu B, Dai Q, Zhou J, Yang Y, Dong R, Ruan C, Dong S, Xu J
Advanced healthcare materials 2020 Jul;9(13):e2000353
Advanced healthcare materials 2020 Jul;9(13):e2000353
Graphene oxide-coated porous titanium for pulp sealing: an antibacterial and dentino-inductive restorative material.
Sun N, Yin S, Lu Y, Zhang W, Jiang X
Journal of materials chemistry. B 2020 Jul 8;8(26):5606-5619
Journal of materials chemistry. B 2020 Jul 8;8(26):5606-5619
Exosomes from adipose-derived mesenchymal stem cells prevent cardiomyocyte apoptosis induced by oxidative stress.
Liu Z, Xu Y, Wan Y, Gao J, Chu Y, Li J
Cell death discovery 2019;5:79
Cell death discovery 2019;5:79
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer.
He W, Liang B, Wang C, Li S, Zhao Y, Huang Q, Liu Z, Yao Z, Wu Q, Liao W, Zhang S, Liu Y, Xiang Y, Liu J, Shi M
Oncogene 2019 Jun;38(23):4637-4654
Oncogene 2019 Jun;38(23):4637-4654
Upregulation of nectin-4 is associated with ITGB1 and vasculogenic mimicry and may serve as a predictor of poor prognosis in colorectal cancer.
Zhang J, Liu K, Peng P, Li S, Ye Z, Su Y, Liu S, Qin M, Huang J
Oncology letters 2019 Aug;18(2):1163-1170
Oncology letters 2019 Aug;18(2):1163-1170
Proteomic Analysis of Plasma Membrane Proteins of Antler Stem Cells Using Label-Free LC⁻MS/MS.
Wang D, Ba H, Li C, Zhao Q, Li C
International journal of molecular sciences 2018 Nov 5;19(11)
International journal of molecular sciences 2018 Nov 5;19(11)
Podocyte injury elicits loss and recovery of cellular forces.
Haley KE, Kronenberg NM, Liehm P, Elshani M, Bell C, Harrison DJ, Gather MC, Reynolds PA
Science advances 2018 Jun;4(6):eaap8030
Science advances 2018 Jun;4(6):eaap8030
Osteogenesis potential of different titania nanotubes in oxidative stress microenvironment.
Yu Y, Shen X, Luo Z, Hu Y, Li M, Ma P, Ran Q, Dai L, He Y, Cai K
Biomaterials 2018 Jun;167:44-57
Biomaterials 2018 Jun;167:44-57
Polymer Self-Assembled BMSCs with Cancer Tropism and Programmed Homing.
Zhang S, Liu Y, Derakhshanfar S, He W, Huang Q, Dong S, Rao J, Luo GX, Zhong W, Liao W, Shi M, Xing M
Advanced healthcare materials 2018 Dec;7(23):e1800118
Advanced healthcare materials 2018 Dec;7(23):e1800118
Annexin A4 fucosylation enhances its interaction with the NF-kB p50 and promotes tumor progression of ovarian clear cell carcinoma.
Wang H, Deng L, Cai M, Zhuang H, Zhu L, Hao Y, Gao J, Liu J, Li X, Lin B
Oncotarget 2017 Dec 8;8(64):108093-108107
Oncotarget 2017 Dec 8;8(64):108093-108107
Micro- and Nanoscale Topographies on Silk Regulate Gene Expression of Human Corneal Epithelial Cells.
Kang KB, Lawrence BD, Gao XR, Luo Y, Zhou Q, Liu A, Guaiquil VH, Rosenblatt MI
Investigative ophthalmology & visual science 2017 Dec 1;58(14):6388-6398
Investigative ophthalmology & visual science 2017 Dec 1;58(14):6388-6398
Inhibition of peritoneal metastasis of human gastric cancer cells by dextran sulphate through the reduction in HIF-1α and ITGβ1 expression.
Xu Y, Jin X, Huang Y, Dong J, Wang H, Wang X, Cao X
Oncology reports 2016 May;35(5):2624-34
Oncology reports 2016 May;35(5):2624-34
Hen egg white ovomacroglobulin promotes fibroblast migration via mediating cell adhesion and cytoskeleton.
Geng F, Huang X, Ma M
Journal of the science of food and agriculture 2016 Jul;96(9):3188-94
Journal of the science of food and agriculture 2016 Jul;96(9):3188-94
Silence of fibronectin 1 increases cisplatin sensitivity of non-small cell lung cancer cell line.
Gao W, Liu Y, Qin R, Liu D, Feng Q
Biochemical and biophysical research communications 2016 Jul 15;476(1):35-41
Biochemical and biophysical research communications 2016 Jul 15;476(1):35-41
KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway.
Li L, Duan T, Wang X, Zhang RH, Zhang M, Wang S, Wang F, Wu Y, Huang H, Kang T
Scientific reports 2016 Feb 5;6:20460
Scientific reports 2016 Feb 5;6:20460
17β-Estradiol protects against apoptosis induced by levofloxacin in rat nucleus pulposus cells by upregulating integrin α2β1.
Yang SD, Ma L, Gu TX, Ding WY, Zhang F, Shen Y, Zhang YZ, Yang DL, Zhang D, Sun YP, Song YL
Apoptosis : an international journal on programmed cell death 2014 May;19(5):789-800
Apoptosis : an international journal on programmed cell death 2014 May;19(5):789-800
A monoclonal antibody targeting neuropilin-1 inhibits adhesion of MCF7 breast cancer cells to fibronectin by suppressing the FAK/p130cas signaling pathway.
Zeng F, Luo F, Lv S, Zhang H, Cao C, Chen X, Wang S, Li Z, Wang X, Dou X, Dai Y, He M, Zhang Y, Lv H, Yan J, Chen Y
Anti-cancer drugs 2014 Jul;25(6):663-72
Anti-cancer drugs 2014 Jul;25(6):663-72
Sine oculis homeobox homolog 1 promotes α5β1-mediated invasive migration and metastasis of cervical cancer cells.
Liu D, Zhang XX, Wan DY, Xi BX, Ma D, Wang H, Gao QL
Biochemical and biophysical research communications 2014 Apr 4;446(2):549-54
Biochemical and biophysical research communications 2014 Apr 4;446(2):549-54
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- The Integrin beta-1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Integrin beta-1. This antibody recognizes human,mouse,rat antigen. The Integrin beta-1 antibody has been validated for the following applications: ELISA, WB analysis.