BS4646

antibody from Bioworld Technology, Inc
Targeting: ITGB1 CD29, FNRB, GPIIA, MDF2, MSK12
Provider product page for BS4646
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS4646 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Integrin ÉÇ1 (phospho T789) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human Integrin ÉÇ1 around the phosphorylation site of Threonine 789.
Description
Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands, such as fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ITGB1 protein structure - BS4646 shown in red.