Antibody data
- Antibody Data
- Antigen structure
- References [46]
- Comments [0]
- Validations [0]
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- Product number
- 26918-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- Integrin Beta 1 antibody
- Antibody type
- Polyclonal
- Description
- Integrin Beta 1 antibody (Cat. #26918-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Early-activated extracellular matrix proteins shape the metabolic and spatial dynamics of the kidney fibrotic microenvironment.
A pan-cancer single-cell transcriptomic atlas of human bone metastases.
Roxadustat: A catalyst for diabetic wound healing through re-epithelialization and angiogenesis.
Mechanism of retinal angiogenesis induced by HIF-1α and HIF-2α under hyperoxic conditions.
FERMT2 drives anoikis resistance and peritoneal metastasis by enhancing extracellular matrix deposition in gastric cancer.
AP2A1 modulates cell states between senescence and rejuvenation.
Angiopoietin-2 regulates the phenotypic switch of vascular smooth muscle cells.
ST6GALNAC1-mediated sialylation in uterine endometrial epithelium facilitates the epithelium-embryo attachment.
In situ osteogenic activation of mesenchymal stem cells by the blood clot biomimetic mechanical microenvironment.
ALKBH5 alleviates lower extremity arteriosclerosis by regulating ITGB1 demethylation and influencing macrophage polarization.
IFIT3 promotes lymph node metastasis by interacting with LASP1 to activate FAK-ERK signaling in esophageal squamous cell carcinoma.
Triptolide targets PPP2CA/ITGA5 axis to suppress lactate-driven ovarian cancer progression.
Long-term expansion of basal cells and the novel differentiation methods identify mechanisms for switching Claudin expression in normal epithelia.
Highly Ordered Nanotube-Like Microstructure on Titanium Dental Implant Surface Fabricated via Anodization Enhanced Cell Adhesion and Migration of Human Gingival Fibroblasts.
Genetically engineered electrospinning contributes to spinal cord injury repair by regulating the immune microenvironment.
Exosomes derived from ITGB1 modified Telocytes alleviates LPS-induced inflammation and oxidative stress through YAP1/ROS axis.
Activation of cell adhesion and migration is an early event of platelet-rich plasma (PRP)-dependent stimulation of human adipose-derived stem/stromal cells.
Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.
YTHDF1 promotes the osteolytic bone metastasis of breast cancer via inducing EZH2 and CDH11 translation.
Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that is dependent on the enzymatic activity that targets the cell-surface annexin A2.
Triptolide attenuates pulmonary fibrosis by inhibiting fibrotic extracellular matrix remodeling mediated by MMPs/LOX/integrin.
MAGT1 deficiency in XMEN disease is associated with severe platelet dysfunction and impaired platelet glycoprotein N-glycosylation.
Myelin Debris Impairs Tight Junctions and Promotes the Migration of Microvascular Endothelial Cells in the Injured Spinal Cord.
Step-wise CAG@PLys@PDA-Cu(2+) modification on micropatterned nanofibers for programmed endothelial healing.
Effect of polymorphism in Rhinolophus affinis ACE2 on entry of SARS-CoV-2 related bat coronaviruses.
FRMD3 inhibits the growth and metastasis of breast cancer through the ubiquitination-mediated degradation of vimentin and subsequent impairment of focal adhesion.
Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice.
Low-dose graphene oxide promotes tumor cells proliferation by activating PI3K-AKT-mTOR signaling via cellular membrane protein integrin αV.
A functionalized self-assembling peptide containing E7 and YIGSR sequences enhances neuronal differentiation of spermatogonial stem cells on aligned PCL fibers for spinal cord injury repair.
Inhibition of galectin-3 ameliorates high-glucose-induced oxidative stress and inflammation in ARPE-19 cells.
Phosphorylation of guanosine monophosphate reductase triggers a GTP-dependent switch from pro- to anti-oncogenic function of EPHA4.
Essential Role of Sptan1 in Cochlear Hair Cell Morphology and Function Via Focal Adhesion Signaling.
Ups and downs: The PPARγ/p-PPARγ seesaw of follistatin-like 1 and integrin receptor signaling in adipogenesis.
Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy.
TBC1 domain family member 23 interacts with Ras-related protein Rab-11A to promote poor prognosis of non-small-cell lung cancer via β1-integrin.
Regulation of local GTP availability controls RAC1 activity and cell invasion.
Engineered Biomimetic Nanoplatform Protects the Myocardium Against Ischemia/Reperfusion Injury by Inhibiting Pyroptosis.
Angiopoietin 2 stimulates trophoblast invasion via a mechanism associated with JNK signaling.
Unveiling the CHO surfaceome: Identification of cell surface proteins reveals cell aggregation-relevant mechanisms.
Fe(3)O(4)@M nanoparticles for MRI-targeted detection in the early lesions of atherosclerosis.
Protective Role of Tangshen Formula on the Progression of Renal Damage in db/db Mice by TRPC6/Talin1 Pathway in Podocytes.
VCAM-1 secreted from cancer-associated fibroblasts enhances the growth and invasion of lung cancer cells through AKT and MAPK signaling.
FN-EDA mediates angiogenesis of hepatic fibrosis via integrin-VEGFR2 in a CD63 synergetic manner.
Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway.
Silencing Formin-like 2 inhibits growth and metastasis of gastric cancer cells through suppressing internalization of integrins.
Single-Cell Analysis of the Impact of Host Cell Heterogeneity on Infection with Foot-and-Mouth Disease Virus.
Gui Y, Li W, Liu JJ, Wang Y, Jones C, Bansal R, Mallari SM, Shaffer HW, Yu Y, Fu H, Tang TT, Liu S, Liu Y, Zhou D
Nature metabolism 2026 Mar;8(3):604-623
Nature metabolism 2026 Mar;8(3):604-623
A pan-cancer single-cell transcriptomic atlas of human bone metastases.
Wang S, Ma F, Wang D, Yu Q, Zheng H, Chen Z, Zhao S, Xu L, Ye Q, Tan Y, Huang W, Sun Z, Wu Z, Cai W, Fang M, Cheng M, Ji Y, Zhang Y, Gu B, Song S, Chen Y, Zhang J, Shao Y, Yan W, Sun Y
Cell reports. Medicine 2026 Feb 17;7(2):102583
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Roxadustat: A catalyst for diabetic wound healing through re-epithelialization and angiogenesis.
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Mechanism of retinal angiogenesis induced by HIF-1α and HIF-2α under hyperoxic conditions.
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FERMT2 drives anoikis resistance and peritoneal metastasis by enhancing extracellular matrix deposition in gastric cancer.
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AP2A1 modulates cell states between senescence and rejuvenation.
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Cellular signalling 2025 Mar;127:111616
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Angiopoietin-2 regulates the phenotypic switch of vascular smooth muscle cells.
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Mar 15;39(5):e70434
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ST6GALNAC1-mediated sialylation in uterine endometrial epithelium facilitates the epithelium-embryo attachment.
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Journal of advanced research 2025 Jun;72:197-212
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In situ osteogenic activation of mesenchymal stem cells by the blood clot biomimetic mechanical microenvironment.
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Nature communications 2025 Jan 30;16(1):1162
Nature communications 2025 Jan 30;16(1):1162
ALKBH5 alleviates lower extremity arteriosclerosis by regulating ITGB1 demethylation and influencing macrophage polarization.
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IFIT3 promotes lymph node metastasis by interacting with LASP1 to activate FAK-ERK signaling in esophageal squamous cell carcinoma.
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Triptolide targets PPP2CA/ITGA5 axis to suppress lactate-driven ovarian cancer progression.
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Chinese medicine 2025 Aug 6;20(1):122
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Long-term expansion of basal cells and the novel differentiation methods identify mechanisms for switching Claudin expression in normal epithelia.
Inoko A, Soga N, Suzuki M, Kiyono T, Ikenouchi J, Kojima T, Sato Y, Saito D, Miyamoto T, Goshima N, Ito H, Kasai K
Scientific reports 2025 Apr 9;15(1):12172
Scientific reports 2025 Apr 9;15(1):12172
Highly Ordered Nanotube-Like Microstructure on Titanium Dental Implant Surface Fabricated via Anodization Enhanced Cell Adhesion and Migration of Human Gingival Fibroblasts.
Deng Z, Yu L, Kuang Y, Zhou Z, Li X
International journal of nanomedicine 2024;19:2469-2485
International journal of nanomedicine 2024;19:2469-2485
Genetically engineered electrospinning contributes to spinal cord injury repair by regulating the immune microenvironment.
Sun Y, Wu J, Zhou L, Wang W, Wang H, Sun S, Xu Y, Zhang L, Jiang X, Zhu G, Xi K, Gu Y, Chen L
Frontiers in bioengineering and biotechnology 2024;12:1415527
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Exosomes derived from ITGB1 modified Telocytes alleviates LPS-induced inflammation and oxidative stress through YAP1/ROS axis.
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Heliyon 2024 Mar 15;10(5):e27086
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Activation of cell adhesion and migration is an early event of platelet-rich plasma (PRP)-dependent stimulation of human adipose-derived stem/stromal cells.
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Human cell 2024 Jan;37(1):181-192
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Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.
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JCI insight 2024 Jan 23;9(2)
JCI insight 2024 Jan 23;9(2)
YTHDF1 promotes the osteolytic bone metastasis of breast cancer via inducing EZH2 and CDH11 translation.
Wang S, Xu L, Wang D, Zhao S, Li K, Ma F, Yao Q, Zhang Y, Wu Z, Shao Y, Song S, Yan W
Cancer letters 2024 Aug 10;597:217047
Cancer letters 2024 Aug 10;597:217047
Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that is dependent on the enzymatic activity that targets the cell-surface annexin A2.
Komalasari NLGY, Tomonobu N, Kinoshita R, Chen Y, Sakaguchi Y, Gohara Y, Jiang F, Yamamoto KI, Murata H, Ruma IMW, Sumardika IW, Zhou J, Yamauchi A, Kuribayashi F, Inoue Y, Toyooka S, Sakaguchi M
Frontiers in oncology 2023;13:1142907
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Triptolide attenuates pulmonary fibrosis by inhibiting fibrotic extracellular matrix remodeling mediated by MMPs/LOX/integrin.
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MAGT1 deficiency in XMEN disease is associated with severe platelet dysfunction and impaired platelet glycoprotein N-glycosylation.
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Myelin Debris Impairs Tight Junctions and Promotes the Migration of Microvascular Endothelial Cells in the Injured Spinal Cord.
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Effect of polymorphism in Rhinolophus affinis ACE2 on entry of SARS-CoV-2 related bat coronaviruses.
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PLoS pathogens 2023 Jan;19(1):e1011116
PLoS pathogens 2023 Jan;19(1):e1011116
FRMD3 inhibits the growth and metastasis of breast cancer through the ubiquitination-mediated degradation of vimentin and subsequent impairment of focal adhesion.
Shao W, Li J, Piao Q, Yao X, Li M, Wang S, Song Z, Sun Y, Zheng L, Wang G, Liu L, Yu C, Huang Y, Bao Y, Sun L
Cell death & disease 2023 Jan 11;14(1):13
Cell death & disease 2023 Jan 11;14(1):13
Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice.
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Military Medical Research 2023 Feb 22;10(1):7
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Low-dose graphene oxide promotes tumor cells proliferation by activating PI3K-AKT-mTOR signaling via cellular membrane protein integrin αV.
Zheng Z, Halifu A, Ma J, Liu L, Fu Q, Yi B, Du E, Tian D, Xu Y, Zhang Z, Zhu J
Environmental pollution (Barking, Essex : 1987) 2023 Aug 1;330:121817
Environmental pollution (Barking, Essex : 1987) 2023 Aug 1;330:121817
A functionalized self-assembling peptide containing E7 and YIGSR sequences enhances neuronal differentiation of spermatogonial stem cells on aligned PCL fibers for spinal cord injury repair.
Wang Z, Jia S, Xu H, Wang X, Lu B, Wu W, Huang D, Kong L, Kang X, Tian F, Zhu L, Hao D
Theranostics 2022;12(17):7567-7585
Theranostics 2022;12(17):7567-7585
Inhibition of galectin-3 ameliorates high-glucose-induced oxidative stress and inflammation in ARPE-19 cells.
Li M, Tian M, Jiang X, Liu Y, Wang Y, Li Y
Cutaneous and ocular toxicology 2022 Jun;41(2):179-186
Cutaneous and ocular toxicology 2022 Jun;41(2):179-186
Phosphorylation of guanosine monophosphate reductase triggers a GTP-dependent switch from pro- to anti-oncogenic function of EPHA4.
Wolff DW, Deng Z, Bianchi-Smiraglia A, Foley CE, Han Z, Wang X, Shen S, Rosenberg MM, Moparthy S, Yun DH, Chen J, Baker BK, Roll MV, Magiera AJ, Li J, Hurley E, Feltri ML, Cox AO, Lee J, Furdui CM, Liu L, Bshara W, LaConte LEW, Kandel ES, Pasquale EB, Qu J, Hedstrom L, Nikiforov MA
Cell chemical biology 2022 Jun 16;29(6):970-984.e6
Cell chemical biology 2022 Jun 16;29(6):970-984.e6
Essential Role of Sptan1 in Cochlear Hair Cell Morphology and Function Via Focal Adhesion Signaling.
Yao Q, Wang H, Chen H, Li Z, Jiang Y, Li Z, Wang J, Xing Y, Liu F, Yu D, Yin S
Molecular neurobiology 2022 Jan;59(1):386-404
Molecular neurobiology 2022 Jan;59(1):386-404
Ups and downs: The PPARγ/p-PPARγ seesaw of follistatin-like 1 and integrin receptor signaling in adipogenesis.
Fang D, Shi X, Jia X, Yang C, Wang L, Du B, Lu T, Shan L, Gao Y
Molecular metabolism 2022 Jan;55:101400
Molecular metabolism 2022 Jan;55:101400
Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy.
Liu L, Li X, Bu W, Jin N, Meng Y, Wang Y, Wang D, Xu X, Zhou D, Sun H
Materials today. Bio 2022 Dec;16:100344
Materials today. Bio 2022 Dec;16:100344
TBC1 domain family member 23 interacts with Ras-related protein Rab-11A to promote poor prognosis of non-small-cell lung cancer via β1-integrin.
Zhang Y, Su H, Wudu M, Ren H, Xu Y, Zhang Q, Jiang J, Wang Q, Jiang X, Zhang B, Liu Z, Zou Z, Qiu X
Journal of cellular and molecular medicine 2021 Sep;25(18):8821-8835
Journal of cellular and molecular medicine 2021 Sep;25(18):8821-8835
Regulation of local GTP availability controls RAC1 activity and cell invasion.
Bianchi-Smiraglia A, Wolff DW, Marston DJ, Deng Z, Han Z, Moparthy S, Wombacher RM, Mussell AL, Shen S, Chen J, Yun DH, O'Brien Cox A, Furdui CM, Hurley E, Feltri ML, Qu J, Hollis T, Kengne JBN, Fongang B, Sousa RJ, Kandel ME, Kandel ES, Hahn KM, Nikiforov MA
Nature communications 2021 Oct 19;12(1):6091
Nature communications 2021 Oct 19;12(1):6091
Engineered Biomimetic Nanoplatform Protects the Myocardium Against Ischemia/Reperfusion Injury by Inhibiting Pyroptosis.
Wei Y, Zhu M, Li S, Hong T, Guo X, Li Y, Liu Y, Hou X, He B
ACS applied materials & interfaces 2021 Jul 28;13(29):33756-33766
ACS applied materials & interfaces 2021 Jul 28;13(29):33756-33766
Angiopoietin 2 stimulates trophoblast invasion via a mechanism associated with JNK signaling.
Hou H, Ning F, Zhang JY, Lu Q, Zhang M, Wu P, Chen M, Lash GE
Molecular human reproduction 2021 Feb 27;27(3)
Molecular human reproduction 2021 Feb 27;27(3)
Unveiling the CHO surfaceome: Identification of cell surface proteins reveals cell aggregation-relevant mechanisms.
Klingler F, Mathias S, Schneider H, Buck T, Raab N, Zeh N, Shieh YW, Pfannstiel J, Otte K
Biotechnology and bioengineering 2021 Aug;118(8):3015-3028
Biotechnology and bioengineering 2021 Aug;118(8):3015-3028
Fe(3)O(4)@M nanoparticles for MRI-targeted detection in the early lesions of atherosclerosis.
Huang X, Lin C, Luo C, Guo Y, Li J, Wang Y, Xu J, Zhang Y, Wang H, Liu Z, Chen B
Nanomedicine : nanotechnology, biology, and medicine 2021 Apr;33:102348
Nanomedicine : nanotechnology, biology, and medicine 2021 Apr;33:102348
Protective Role of Tangshen Formula on the Progression of Renal Damage in db/db Mice by TRPC6/Talin1 Pathway in Podocytes.
Wang Q, Tian X, Zhou W, Wang Y, Zhao H, Li J, Zhou X, Zhang H, Zhao T, Li P
Journal of diabetes research 2020;2020:3634974
Journal of diabetes research 2020;2020:3634974
VCAM-1 secreted from cancer-associated fibroblasts enhances the growth and invasion of lung cancer cells through AKT and MAPK signaling.
Zhou Z, Zhou Q, Wu X, Xu S, Hu X, Tao X, Li B, Peng J, Li D, Shen L, Cao Y, Yang L
Cancer letters 2020 Mar 31;473:62-73
Cancer letters 2020 Mar 31;473:62-73
FN-EDA mediates angiogenesis of hepatic fibrosis via integrin-VEGFR2 in a CD63 synergetic manner.
Su X, Ma X, Xie X, Wu H, Wang L, Feng Y, Yu Z, Liu C, Qi J, Zhu Q
Cell death discovery 2020 Dec 8;6(1):140
Cell death discovery 2020 Dec 8;6(1):140
Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway.
Wang X, Adegoke EO, Ma M, Huang F, Zhang H, Adeniran SO, Zheng P, Zhang G
Theriogenology 2019 Oct 15;138:84-93
Theriogenology 2019 Oct 15;138:84-93
Silencing Formin-like 2 inhibits growth and metastasis of gastric cancer cells through suppressing internalization of integrins.
Zhong B, Wang K, Xu H, Kong F
Cancer cell international 2018;18:79
Cancer cell international 2018;18:79
Single-Cell Analysis of the Impact of Host Cell Heterogeneity on Infection with Foot-and-Mouth Disease Virus.
Xin X, Wang H, Han L, Wang M, Fang H, Hao Y, Li J, Zhang H, Zheng C, Shen C
Journal of virology 2018 May 1;92(9)
Journal of virology 2018 May 1;92(9)
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