Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 303001 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#303001, RRID:AB_314317
- Product name
- Purified anti-human CD29
- Antibody type
- Monoclonal
- Antigen
- CD29
- Description
- CD29 is a 130 kD single chain type I glycoprotein, known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins which include CD29 bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions.
- Reactivity
- Human, Bovine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
Submitted references KCNQ5/K(v)7.5 potassium channel expression and subcellular localization in primate retinal pigment epithelium and neural retina.
Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers.
Prostate-specific membrane antigen regulates angiogenesis by modulating integrin signal transduction.
Zhang X, Yang D, Hughes BA
American journal of physiology. Cell physiology 2011 Nov;301(5):C1017-26
American journal of physiology. Cell physiology 2011 Nov;301(5):C1017-26
Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers.
Pillozzi S, Masselli M, De Lorenzo E, Accordi B, Cilia E, Crociani O, Amedei A, Veltroni M, D'Amico M, Basso G, Becchetti A, Campana D, Arcangeli A
Blood 2011 Jan 20;117(3):902-14
Blood 2011 Jan 20;117(3):902-14
Prostate-specific membrane antigen regulates angiogenesis by modulating integrin signal transduction.
Conway RE, Petrovic N, Li Z, Heston W, Wu D, Shapiro LH
Molecular and cellular biology 2006 Jul;26(14):5310-24
Molecular and cellular biology 2006 Jul;26(14):5310-24
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Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes stained with purified TS2/16, followed by anti-mouse IgGs FITC
- Conjugate
- Unconjugated