20174-1-AP
antibody from Proteintech Group
Targeting: MARK4
FLJ90097, KIAA1860, MARKL1, Nbla00650, PAR-1D
Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Immunohistochemistry [2]
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Validation data
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- Product number
- 20174-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20174-1-AP, RRID:AB_2636847
- Product name
- MARK4 antibody
- Antibody type
- Polyclonal
- Description
- MARK4 antibody (Cat. #20174-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A cell-penetrating peptide derived from SARS-CoV-2 protein Orf9b allosterically inhibits MARK4 activity and mitigates tau toxicity.
Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis.
MARK2 and MARK4 Regulate Sertoli Cell BTB Dynamics Through Microtubule and Actin Cytoskeletons.
The Non-hormonal Male Contraceptive Adjudin Exerts its Effects via MAPs and Signaling Proteins mTORC1/rpS6 and FAK-Y407.
KIF15 supports spermatogenesis via its effects on Sertoli cell microtubule, actin, vimentin, and septin cytoskeletons.
NC1-Peptide From Collagen α3 (IV) Chains in the Basement Membrane of Testes Regulates Spermatogenesis via p-FAK-Y407.
Endogenously produced LG3/4/5-peptide protects testes against toxicant-induced injury.
NC1-peptide regulates spermatogenesis through changes in cytoskeletal organization mediated by EB1.
Regulation of BTB Dynamics in Spermatogenesis-Insights From the Adjudin Model.
CAMSAP2 Is a Microtubule Minus-End Targeting Protein That Regulates BTB Dynamics Through Cytoskeletal Organization.
Cdc42 is involved in NC1 peptide-regulated BTB dynamics through actin and microtubule cytoskeletal reorganization.
F5-Peptide and mTORC1/rpS6 Effectively Enhance BTB Transport Function in the Testis-Lesson From the Adjudin Model.
Regulation of the blood-testis barrier by a local axis in the testis: role of laminin α2 in the basement membrane.
Sperm Release at Spermiation Is Regulated by Changes in the Organization of Actin- and Microtubule-Based Cytoskeletons at the Apical Ectoplasmic Specialization-A Study Using the Adjudin Model.
Basement Membrane Laminin α2 Regulation of BTB Dynamics via Its Effects on F-Actin and Microtubule Cytoskeletons Is Mediated Through mTORC1 Signaling.
Oba T, Homma D, Limlingan SJM, Fukuchi A, Asada A, Saito T, Ando K
Neurobiology of disease 2023 Nov;188:106334
Neurobiology of disease 2023 Nov;188:106334
Microtubule affinity regulating kinase 4 promoted activation of the NLRP3 inflammasome-mediated pyroptosis in periodontitis.
Wang L, Pu W, Wang C, Lei L, Li H
Journal of oral microbiology 2022;14(1):2015130
Journal of oral microbiology 2022;14(1):2015130
MARK2 and MARK4 Regulate Sertoli Cell BTB Dynamics Through Microtubule and Actin Cytoskeletons.
Tang EI, Cheng CY
Endocrinology 2022 Oct 11;163(11)
Endocrinology 2022 Oct 11;163(11)
The Non-hormonal Male Contraceptive Adjudin Exerts its Effects via MAPs and Signaling Proteins mTORC1/rpS6 and FAK-Y407.
Wang L, Yan M, Li H, Wu S, Ge R, Wong CKC, Silvestrini B, Sun F, Cheng CY
Endocrinology 2021 Jan 1;162(1)
Endocrinology 2021 Jan 1;162(1)
KIF15 supports spermatogenesis via its effects on Sertoli cell microtubule, actin, vimentin, and septin cytoskeletons.
Wu S, Lv L, Li L, Wang L, Mao B, Li J, Shen X, Ge R, Wong CKC, Sun F, Cheng CY
Endocrinology 2021 Apr 1;162(4)
Endocrinology 2021 Apr 1;162(4)
NC1-Peptide From Collagen α3 (IV) Chains in the Basement Membrane of Testes Regulates Spermatogenesis via p-FAK-Y407.
Li H, Liu S, Wu S, Ge R, Cheng CY
Endocrinology 2020 Oct 1;161(10)
Endocrinology 2020 Oct 1;161(10)
Endogenously produced LG3/4/5-peptide protects testes against toxicant-induced injury.
Li L, Mao B, Wu S, Li H, Lv L, Ge R, Cheng CY
Cell death & disease 2020 Jun 8;11(6):436
Cell death & disease 2020 Jun 8;11(6):436
NC1-peptide regulates spermatogenesis through changes in cytoskeletal organization mediated by EB1.
Liu S, Li H, Wu S, Li L, Ge R, Cheng CY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):3105-3128
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):3105-3128
Regulation of BTB Dynamics in Spermatogenesis-Insights From the Adjudin Model.
Mao BP, Li L, Yan M, Ge R, Lian Q, Cheng CY
Toxicological sciences : an official journal of the Society of Toxicology 2019 Nov 1;172(1):75-88
Toxicological sciences : an official journal of the Society of Toxicology 2019 Nov 1;172(1):75-88
CAMSAP2 Is a Microtubule Minus-End Targeting Protein That Regulates BTB Dynamics Through Cytoskeletal Organization.
Mao BP, Li L, Ge R, Li C, Wong CKC, Silvestrini B, Lian Q, Cheng CY
Endocrinology 2019 Jun 1;160(6):1448-1467
Endocrinology 2019 Jun 1;160(6):1448-1467
Cdc42 is involved in NC1 peptide-regulated BTB dynamics through actin and microtubule cytoskeletal reorganization.
Su W, Cheng CY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):14461-14478
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):14461-14478
F5-Peptide and mTORC1/rpS6 Effectively Enhance BTB Transport Function in the Testis-Lesson From the Adjudin Model.
Mao B, Li L, Yan M, Wong CKC, Silvestrini B, Li C, Ge R, Lian Q, Cheng CY
Endocrinology 2019 Aug 1;160(8):1832-1853
Endocrinology 2019 Aug 1;160(8):1832-1853
Regulation of the blood-testis barrier by a local axis in the testis: role of laminin α2 in the basement membrane.
Gao Y, Mruk D, Chen H, Lui WY, Lee WM, Cheng CY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Feb;31(2):584-597
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Feb;31(2):584-597
Sperm Release at Spermiation Is Regulated by Changes in the Organization of Actin- and Microtubule-Based Cytoskeletons at the Apical Ectoplasmic Specialization-A Study Using the Adjudin Model.
Li L, Tang EI, Chen H, Lian Q, Ge R, Silvestrini B, Cheng CY
Endocrinology 2017 Dec 1;158(12):4300-4316
Endocrinology 2017 Dec 1;158(12):4300-4316
Basement Membrane Laminin α2 Regulation of BTB Dynamics via Its Effects on F-Actin and Microtubule Cytoskeletons Is Mediated Through mTORC1 Signaling.
Gao Y, Chen H, Lui WY, Lee WM, Cheng CY
Endocrinology 2017 Apr 1;158(4):963-978
Endocrinology 2017 Apr 1;158(4):963-978
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 20174-1-AP(MARK4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MARK4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human MARK4. This antibody recognizes human,mouse,rat antigen. The MARK4 antibody has been validated for the following applications: ELISA, IHC analysis.