Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- 13054-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- THRSP antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated THRSP antibody (Cat. #13054-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references MIF-mediated crosstalk between THRSP + hepatocytes and CD74 + lipid-associated macrophages in hepatic periportal zone drives MASH.
Thyroid hormones inhibit tumor progression and enhance the antitumor activity of lenvatinib in hepatocellular carcinoma via reprogramming glucose metabolism.
Spatial Transcriptomic Study Reveals Heterogeneous Metabolic Adaptation and a Role of Pericentral PPARα/CAR/Ces2a Axis During Fasting in Mouse Liver.
Artesunate remarkably alleviates interstitial cystitis/bladder pain syndrome in a murine model: Novel molecular signature deciphered by bulk tissue and single-cell transcriptomic analysis.
Insulin-inducible THRSP maintains mitochondrial function and regulates sphingolipid metabolism in human adipocytes.
Elevated serum S14 levels are associated with more severe liver steatosis by ultrasonography.
The serum level of a novel lipogenic protein Spot 14 was reduced in metabolic syndrome.
MiR-451a attenuates free fatty acids-mediated hepatocyte steatosis by targeting the thyroid hormone responsive spot 14 gene.
Serum Spot 14 concentration is negatively associated with thyroid-stimulating hormone level.
Xu X, Li H, Lin H, Li Q, Liu Y, Huang W, Yang J, Li N, Gao Z, Wang S, Shen H, Xue W, Yuan H, Wang W, Shuai J, Liu J, Yin S, Liu F
Hepatology (Baltimore, Md.) 2026 Apr 1;83(4):868-887
Hepatology (Baltimore, Md.) 2026 Apr 1;83(4):868-887
Thyroid hormones inhibit tumor progression and enhance the antitumor activity of lenvatinib in hepatocellular carcinoma via reprogramming glucose metabolism.
Yang CC, Yan YC, Pan GQ, Meng GX, Zhang X, Yan LJ, Ding ZN, Wang DX, Li RZ, Li GZ, Dong ZR, Li T
Cell death discovery 2025 Mar 8;11(1):92
Cell death discovery 2025 Mar 8;11(1):92
Spatial Transcriptomic Study Reveals Heterogeneous Metabolic Adaptation and a Role of Pericentral PPARα/CAR/Ces2a Axis During Fasting in Mouse Liver.
Wang S, Xu B, Liang J, Feng Y, Han P, Shen J, Li X, Zheng M, Zhang T, Zhang C, Mi P, Zhang Y, Liu Z, Li S, Yuan D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2405240
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2405240
Artesunate remarkably alleviates interstitial cystitis/bladder pain syndrome in a murine model: Novel molecular signature deciphered by bulk tissue and single-cell transcriptomic analysis.
Wu Y, Shi B, He Y, Wang S, Zhou J, Qi J, Ding J, Wang Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 15;38(23):e70225
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 15;38(23):e70225
Insulin-inducible THRSP maintains mitochondrial function and regulates sphingolipid metabolism in human adipocytes.
Ahonen MA, Höring M, Nguyen VD, Qadri S, Taskinen JH, Nagaraj M, Wabitsch M, Fischer-Posovszky P, Zhou Y, Liebisch G, Haridas PAN, Yki-Järvinen H, Olkkonen VM
Molecular medicine (Cambridge, Mass.) 2022 Jun 17;28(1):68
Molecular medicine (Cambridge, Mass.) 2022 Jun 17;28(1):68
Elevated serum S14 levels are associated with more severe liver steatosis by ultrasonography.
Lin WT, Yang KC, Chen YT, Huang KC, Yang WS
Scientific reports 2021 Dec 17;11(1):24181
Scientific reports 2021 Dec 17;11(1):24181
The serum level of a novel lipogenic protein Spot 14 was reduced in metabolic syndrome.
Chen YT, Tseng PH, Tseng FY, Chi YC, Han DS, Yang WS
PloS one 2019;14(2):e0212341
PloS one 2019;14(2):e0212341
MiR-451a attenuates free fatty acids-mediated hepatocyte steatosis by targeting the thyroid hormone responsive spot 14 gene.
Zeng N, Huang R, Li N, Jiang H, Li R, Wang F, Chen W, Xia M, Wang Q
Molecular and cellular endocrinology 2018 Oct 15;474:260-271
Molecular and cellular endocrinology 2018 Oct 15;474:260-271
Serum Spot 14 concentration is negatively associated with thyroid-stimulating hormone level.
Chen YT, Tseng FY, Chen PL, Chi YC, Han DS, Yang WS
Medicine 2016 Oct;95(40):e5036
Medicine 2016 Oct;95(40):e5036
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The THRSP antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human THRSP. This antibody recognizes human,mouse,rat antigen. The THRSP antibody has been validated for the following applications: ELISA, IHC, WB analysis.