A00066-1
antibody from Boster Biological Technology
Targeting: HMGB1
DKFZp686A04236, HMG1, HMG3, SBP-1
Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- A00066-1 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-HMGB1 Antibody Picoband™
- Antibody type
- Polyclonal
- Description
- Rabbit IgG polyclonal antibody for High mobility group protein B1(HMGB1) detection. Tested with WB, IHC-P, ICC/IF, FCM in Human;Mouse;Rat.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references SHARPIN contributes to sevoflurane-induced neonatal neurotoxicity through up-regulating HMGB1 to repress M2 like-macrophage polarization.
n-3 polyunsaturated fatty acids alleviate the progression of obesity-related osteoarthritis and protect cartilage through inhibiting the HMGB1-RAGE/TLR4 signaling pathway.
Voluntarily wheel running inhibits the growth of CRPC xenograft by inhibiting HMGB1 in mice.
Urolithin A protects against acetaminophen-induced liver injury in mice via sustained activation of Nrf2.
Short-term pretreatment of naringin isolated from Citrus wilsonii Tanaka attenuates rat myocardial ischemia/reperfusion injury.
HMGB1 promotes the development of castration‑resistant prostate cancer by regulating androgen receptor activation.
Citrus fruits are rich in flavonoids for immunoregulation and potential targeting ACE2.
Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy.
Bioinformatic and biochemical findings disclosed anti-hepatic steatosis mechanism of calycosin.
HMGB1 promoted P-glycoprotein at the blood-brain barrier in MCAO rats via TLR4/NF-κB signaling pathway.
Protective effects of mild hypothermia against hepatic injury in rats with acute liver failure.
Celastrol pretreatment attenuates rat myocardial ischemia/ reperfusion injury by inhibiting high mobility group box 1 protein expression via the PI3K/Akt pathway.
Short-Term Hesperidin Pretreatment Attenuates Rat Myocardial Ischemia/Reperfusion Injury by Inhibiting High Mobility Group Box 1 Protein Expression via the PI3K/Akt Pathway.
Effects of Ethyl Pyruvate in Preventing the Development of Diet-induced Atherosclerosis by Blocking the HMGB1 Expression in ApoE-Deficient Mice.
Association of Upregulated HMGB1 and c-IAP2 Proteins With Hepatocellular Carcinoma Development and Progression.
Cai J, Lin Y, Zhou B, Xiao F, Xu G, Lu J
Metabolic brain disease 2024 Jun;39(5):841-853
Metabolic brain disease 2024 Jun;39(5):841-853
n-3 polyunsaturated fatty acids alleviate the progression of obesity-related osteoarthritis and protect cartilage through inhibiting the HMGB1-RAGE/TLR4 signaling pathway.
Xiong T, Huang S, Wang X, Shi Y, He J, Yuan Y, Wang R, Gu H, Liu L
International immunopharmacology 2024 Feb 15;128:111498
International immunopharmacology 2024 Feb 15;128:111498
Voluntarily wheel running inhibits the growth of CRPC xenograft by inhibiting HMGB1 in mice.
Yang Z, Gao Y, He K, Sui X, Chen J, Wang T, Chen M, Wang Z, Yi J, Zhao L
Experimental gerontology 2023 Apr;174:112118
Experimental gerontology 2023 Apr;174:112118
Urolithin A protects against acetaminophen-induced liver injury in mice via sustained activation of Nrf2.
Gao Z, Yi W, Tang J, Sun Y, Huang J, Lan T, Dai X, Xu S, Jin ZG, Wu X
International journal of biological sciences 2022;18(5):2146-2162
International journal of biological sciences 2022;18(5):2146-2162
Short-term pretreatment of naringin isolated from Citrus wilsonii Tanaka attenuates rat myocardial ischemia/reperfusion injury.
Liu W, Cheng L, Li X, Zhao L, Hu X, Ma Z
Naunyn-Schmiedeberg's archives of pharmacology 2022 Sep;395(9):1047-1059
Naunyn-Schmiedeberg's archives of pharmacology 2022 Sep;395(9):1047-1059
HMGB1 promotes the development of castration‑resistant prostate cancer by regulating androgen receptor activation.
Chen J, Xu D, Wang T, Yang Z, Yang Y, He K, Zhao L
Oncology reports 2022 Nov;48(5)
Oncology reports 2022 Nov;48(5)
Citrus fruits are rich in flavonoids for immunoregulation and potential targeting ACE2.
Liu W, Zheng W, Cheng L, Li M, Huang J, Bao S, Xu Q, Ma Z
Natural products and bioprospecting 2022 Feb 14;12(1):4
Natural products and bioprospecting 2022 Feb 14;12(1):4
Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy.
Hubert P, Roncarati P, Demoulin S, Pilard C, Ancion M, Reynders C, Lerho T, Bruyere D, Lebeau A, Radermecker C, Meunier M, Nokin MJ, Hendrick E, Peulen O, Delvenne P, Herfs M
Journal for immunotherapy of cancer 2021 Mar;9(3)
Journal for immunotherapy of cancer 2021 Mar;9(3)
Bioinformatic and biochemical findings disclosed anti-hepatic steatosis mechanism of calycosin.
Cheng X, Liu N, Liu H, Huang N, Sun X, Zhang G
Bioorganic chemistry 2020 Jul;100:103914
Bioorganic chemistry 2020 Jul;100:103914
HMGB1 promoted P-glycoprotein at the blood-brain barrier in MCAO rats via TLR4/NF-κB signaling pathway.
Wang F, Ji S, Wang M, Liu L, Li Q, Jiang F, Cen J, Ji B
European journal of pharmacology 2020 Aug 5;880:173189
European journal of pharmacology 2020 Aug 5;880:173189
Protective effects of mild hypothermia against hepatic injury in rats with acute liver failure.
Zhu Y, Xiang T, Hu D, Shi B, Zhang W, Zhang S, Wu X
Annals of hepatology 2019 Sep-Oct;18(5):770-776
Annals of hepatology 2019 Sep-Oct;18(5):770-776
Celastrol pretreatment attenuates rat myocardial ischemia/ reperfusion injury by inhibiting high mobility group box 1 protein expression via the PI3K/Akt pathway.
Tong S, Zhang L, Joseph J, Jiang X
Biochemical and biophysical research communications 2018 Mar 11;497(3):843-849
Biochemical and biophysical research communications 2018 Mar 11;497(3):843-849
Short-Term Hesperidin Pretreatment Attenuates Rat Myocardial Ischemia/Reperfusion Injury by Inhibiting High Mobility Group Box 1 Protein Expression via the PI3K/Akt Pathway.
Li X, Hu X, Wang J, Xu W, Yi C, Ma R, Jiang H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(5):1850-1862
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(5):1850-1862
Effects of Ethyl Pyruvate in Preventing the Development of Diet-induced Atherosclerosis by Blocking the HMGB1 Expression in ApoE-Deficient Mice.
Xiao H, Liu H, Hou C, Liu Y, Yu Q
Journal of cardiovascular pharmacology 2016 Apr;67(4):299-304
Journal of cardiovascular pharmacology 2016 Apr;67(4):299-304
Association of Upregulated HMGB1 and c-IAP2 Proteins With Hepatocellular Carcinoma Development and Progression.
Bi MR, Zhu LY, Yan BZ, Chen LY, Wang FX, Ma YJ, Yang BS
Hepatitis monthly 2014 Dec;14(12):e23552
Hepatitis monthly 2014 Dec;14(12):e23552
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- HMGB1 was detected in paraffin-embedded sections of mouse liver tissues using rabbit anti- HMGB1 Antigen Affinity purified polyclonal antibody (Catalog # A00066-1) at 1 μg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022).
- Additional image