M00066-1

antibody from Boster Biological Technology
Targeting: HMGB1 DKFZp686A04236, HMG1, HMG3, SBP-1
Provider product page for M00066-1
Western blot
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
M00066-1 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-HMGB1/Hmg 1 Rabbit Monoclonal Antibody
Antibody type
Monoclonal
Description
Monoclonal antibody for HMG 1/HMGB1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: Flow Cytometry, IF, IHC, ICC, WB. Reactive species: Human, Mouse, Rat HMG 1/HMGB1 information: Molecular Weight: 24894 MW; Subcellular Localization: Nucleus . Chromosome . Cytoplasm . Secreted . Cell membrane ; Peripheral membrane protein ; Extracellular side . Endosome . Endoplasmic reticulum-Golgi intermediate compartment . In basal state predominantly nuclear. Shuttles between the cytoplasm and the nucleus (PubMed:12231511, PubMed:17114460). Translocates from the nucleus to the cytoplasm upon autophagy stimulation (PubMed:20819940). Release from macrophages in the extracellular milieu requires the activation of NLRC4 or NLRP3 inflammasomes (By similarity). Passively released to the extracellular milieu from necrotic cells by diffusion, involving the fully reduced HGMB1 which subsequently gets oxidized (PubMed:19811284). Also released from apoptic cells (PubMed:16855214, PubMed:18631454). Active secretion from a variety of immune and non-immune cells such as macrophages, monocytes, neutrophils, dendritic cells and natural killer cells in response to va
Reactivity
Human, Mouse, Rat
Host
Rabbit
Antibody clone number
AAC-8
Vial size
100ug/vial
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage
At -20°C for one year. Avoid repeated freezing and thawing.
HMGB1 protein structure - M00066-1 shown in red.