FNab08051

antibody from FineTest Biotech

Targeting: SNAI1 SLUGH2, SNA, SNAH, SNAIL, SNAIL1

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ELISA

Immunohistochemistry

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Validation data

Product number: FNab08051 - Provider product page
Provider: FineTest Biotech
Product name: SNAI1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Involved in induction of the epithelial to mesenchymal transition(EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate(TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: snail homolog 1(Drosophila)
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

SNAI1 protein structure - FNab08051 shown in red.