BS2321

antibody from Bioworld Technology, Inc

Targeting: KSR2 FLJ25965

Immunocytochemistry

Immunohistochemistry

Antibody data

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Validation data

Product number: BS2321 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#BS2321, RRID:AB_1663642
Product name: Ksr2 (I694) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic peptide, corresponding to amino acids 662-724 of Human Ksr2.
Description: Kinase suppressor of Ras (Ksr) and MAP kinase kinase kinase (MEKK3) are integral members of the MAP kinase pathway. Ksr is a conserved protein that positively regulates Ras signaling and may function as a scaffold for Raf, MEK and ERK. There are two types of Ksr proteins: Ksr-1 and Ksr-2. Ksr-2 plays a key role in Ras-mediated signaling during germline meiotic progression and functions redundantly with Ksr-1 during the development of the excretory system pathway, hermaphrodite vulva, and male spicules. Ksr-2 also functions as a negative regulator of the MEKK3-mediated activation of the MAP kinase pathways (specifically ERK and JNK) and of the NF?B pathways, and it simultaneously inhibits MEKK3-mediated Il-8 production.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

KSR2 protein structure - BS2321 shown in red.