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- References [15]
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- Product number
- 20813-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20813-1-AP, RRID:AB_10697809
- Product name
- KDM1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated KDM1 antibody (Cat. #20813-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Dual function of DOT1L suppresses tumor cell-intrinsic immunogenicity in hepatocellular carcinoma.
Transcriptional Activation of SBNO2 by KDM1A Drives Immune Escape in Lung Cancer.
Modulatory Effect of Curcumin on Expression of Methyltransferase/Demethylase in Colon Cancer Cells: Impact on wt p53, mutp53 and c-Myc.
METTL14 suppresses the expression of YAP1 and the stemness of triple-negative breast cancer.
Candidate biomarkers in brown adipose tissue for post-mortem diagnosis of fatal hypothermia.
Epigenetic Regulation of RNF135 by LSD1 Promotes Stemness Maintenance and Brain Metastasis in Lung Adenocarcinoma.
Inhibition of LSD1 via SP2509 attenuated the progression of rheumatoid arthritis.
Matrix stiffness aggravates osteoarthritis progression through H3K27me3 demethylation induced by mitochondrial damage.
The deubiquitinase USP28 maintains the expression of the transcription factor MYCN and is essential in neuroblastoma cells.
E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC.
4,5-Dimethoxycanthin-6-one is a novel LSD1 inhibitor that inhibits proliferation of glioblastoma cells and induces apoptosis and pyroptosis.
PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex.
The chromatin remodeler SRCAP promotes self-renewal of intestinal stem cells.
The Lysine Specific Demethylase-1 Negatively Regulates the COL9A1 Gene in Human Articular Chondrocytes.
HBXIP and LSD1 Scaffolded by lncRNA Hotair Mediate Transcriptional Activation by c-Myc.
Xu S, Gong R, Liu S, Wang J, Shen Y, Peng C, Feng Q, Luo M, Lan F, Fan J, Cai J, Lan X
Oncogene 2026 May;45(16):1484-1500
Oncogene 2026 May;45(16):1484-1500
Transcriptional Activation of SBNO2 by KDM1A Drives Immune Escape in Lung Cancer.
Pan D, Zhang C
Advanced biology 2026 Mar;10(3):e00639
Advanced biology 2026 Mar;10(3):e00639
Modulatory Effect of Curcumin on Expression of Methyltransferase/Demethylase in Colon Cancer Cells: Impact on wt p53, mutp53 and c-Myc.
Santarelli R, Di Dio C, Di Crosta M, Currà P, Gonnella R, Cirone M
Molecules (Basel, Switzerland) 2025 Jul 22;30(15)
Molecules (Basel, Switzerland) 2025 Jul 22;30(15)
METTL14 suppresses the expression of YAP1 and the stemness of triple-negative breast cancer.
Bai X, Liu J, Zhou S, Wu L, Feng X, Zhang P
Journal of experimental & clinical cancer research : CR 2024 Nov 20;43(1):307
Journal of experimental & clinical cancer research : CR 2024 Nov 20;43(1):307
Candidate biomarkers in brown adipose tissue for post-mortem diagnosis of fatal hypothermia.
Zhang M, Wang N, Guo XS, Wang LL, Wang PF, Cao ZP, Zhang FY, Wang ZW, Guan DW, Zhao R
International journal of legal medicine 2024 Jan;138(1):61-72
International journal of legal medicine 2024 Jan;138(1):61-72
Epigenetic Regulation of RNF135 by LSD1 Promotes Stemness Maintenance and Brain Metastasis in Lung Adenocarcinoma.
Qu X, Ding T, Zhao H, Wang L
Environmental toxicology 2024 Dec;39(12):5321-5333
Environmental toxicology 2024 Dec;39(12):5321-5333
Inhibition of LSD1 via SP2509 attenuated the progression of rheumatoid arthritis.
Yu Z, Li P, Gao D, Hu Y, Xia F, Liu L, Liu J, Liu W, Zhang H
Immunologic research 2024 Aug;72(4):797-810
Immunologic research 2024 Aug;72(4):797-810
Matrix stiffness aggravates osteoarthritis progression through H3K27me3 demethylation induced by mitochondrial damage.
Kan T, Li H, Hou L, Cui J, Wang Y, Sun L, Wang L, Yan M, Yu Z
iScience 2024 Aug 16;27(8):110507
iScience 2024 Aug 16;27(8):110507
The deubiquitinase USP28 maintains the expression of the transcription factor MYCN and is essential in neuroblastoma cells.
Li J, Peng J, Wu L, Shen X, Zhen X, Zhang Y, Ma H, Xu Y, Xiong Q, Zhu Q, Zhang P
The Journal of biological chemistry 2023 Jul;299(7):104856
The Journal of biological chemistry 2023 Jul;299(7):104856
E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC.
Tang F, Lu C, He X, Lin W, Xie B, Gao X, Peng Y, Yang D, Sun L, Weng L
Cell reports 2023 Dec 26;42(12):113477
Cell reports 2023 Dec 26;42(12):113477
4,5-Dimethoxycanthin-6-one is a novel LSD1 inhibitor that inhibits proliferation of glioblastoma cells and induces apoptosis and pyroptosis.
Li W, Huang BS, Xiong YY, Yang LJ, Wu LX
Cancer cell international 2022 Jan 18;22(1):32
Cancer cell international 2022 Jan 18;22(1):32
PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex.
Yan L, Jin W, Zhao Q, Cui X, Shi T, Xu Y, Li F, Jin W, Zhang Z, Zhang Z, Tang QQ, Pan D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Aug;8(16):e2102060
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Aug;8(16):e2102060
The chromatin remodeler SRCAP promotes self-renewal of intestinal stem cells.
Ye B, Yang L, Qian G, Liu B, Zhu X, Zhu P, Ma J, Xie W, Li H, Lu T, Wang Y, Wang S, Du Y, Wang Z, Jiang J, Li J, Fan D, Meng S, Wu J, Tian Y, Fan Z
The EMBO journal 2020 Jul 1;39(13):e103786
The EMBO journal 2020 Jul 1;39(13):e103786
The Lysine Specific Demethylase-1 Negatively Regulates the COL9A1 Gene in Human Articular Chondrocytes.
Durand AL, Dufour A, Aubert-Foucher E, Oger-Desfeux C, Pasdeloup M, Lustig S, Servien E, Vaz G, Perrier-Groult E, Mallein-Gerin F, Lafont JE
International journal of molecular sciences 2020 Aug 31;21(17)
International journal of molecular sciences 2020 Aug 31;21(17)
HBXIP and LSD1 Scaffolded by lncRNA Hotair Mediate Transcriptional Activation by c-Myc.
Li Y, Wang Z, Shi H, Li H, Li L, Fang R, Cai X, Liu B, Zhang X, Ye L
Cancer research 2016 Jan 15;76(2):293-304
Cancer research 2016 Jan 15;76(2):293-304
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The KDM1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human KDM1. This antibody recognizes human, mouse antigen. The KDM1 antibody has been validated for the following applications: ELISA, WB analysis.
