Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 10204-2-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10204-2-AP, RRID:AB_2277484
- Product name
- DUSP11 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DUSP11 antibody (Cat. #10204-2-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references DUSP11 is an Intracellular Innate Immune Checkpoint in Lung Adenocarcinoma.
DUSP11 is an intracellular innate immune checkpoint in lung adenocarcinoma.
The immune sensitivity caused by DUSP11, an RNA 5'-end maturation phosphatase, is adjusted by a human non-coding RNA, nc886.
Enhanced Virus Translation Enables miR-122-Independent Hepatitis C Virus Propagation.
Y RNAs are conserved endogenous RIG-I ligands across RNA virus infection and are targeted by HIV-1.
Novel autoantibodies identified in ACPA-negative rheumatoid arthritis.
RIG-I like receptor sensing of host RNAs facilitates the cell-intrinsic immune response to KSHV infection.
RNA triphosphatase DUSP11 enables exonuclease XRN-mediated restriction of hepatitis C virus.
DUSP11 - An RNA phosphatase that regulates host and viral non-coding RNAs in mammalian cells.
DUSP11 activity on triphosphorylated transcripts promotes Argonaute association with noncanonical viral microRNAs and regulates steady-state levels of cellular noncoding RNAs.
Isolation and characterization of DUSP11, a novel p53 target gene.
Thomas BJ, Bai X, Cryer BJ, Escobar SM, Allen LH, Daniels MA, Lange MJ, Burke DH
Cancer immunology research 2025 Nov 3;13(11):1798-1815
Cancer immunology research 2025 Nov 3;13(11):1798-1815
DUSP11 is an intracellular innate immune checkpoint in lung adenocarcinoma.
Thomas BJ, Bai X, Cryer BJ, Escobar SM, Allen LH, Daniels MA, Lange MJ, Burke-Aguero DH
bioRxiv : the preprint server for biology 2025 Jan 27;
bioRxiv : the preprint server for biology 2025 Jan 27;
The immune sensitivity caused by DUSP11, an RNA 5'-end maturation phosphatase, is adjusted by a human non-coding RNA, nc886.
Jang JJ, Lee MJ, Lee MS, Myoung J, Lee HH, Choi BH, Saruuldalai E, Jung YS, Lee HS, Kim Y, Ahn T, Park JL, Kim SY, Park G, Park SJ, Kim SH, Kim JH, Han N, Park EJ, Kang D, Kim IH, Lee YS, Lee YS
Cellular and molecular life sciences : CMLS 2025 Feb 14;82(1):77
Cellular and molecular life sciences : CMLS 2025 Feb 14;82(1):77
Enhanced Virus Translation Enables miR-122-Independent Hepatitis C Virus Propagation.
Panigrahi M, Palmer MA, Wilson JA
Journal of virology 2023 Jul 27;97(7):e0085821
Journal of virology 2023 Jul 27;97(7):e0085821
Y RNAs are conserved endogenous RIG-I ligands across RNA virus infection and are targeted by HIV-1.
Vabret N, Najburg V, Solovyov A, Gopal R, McClain C, Ć ulc P, Balan S, Rahou Y, Beauclair G, Chazal M, Varet H, Legendre R, Sismeiro O, Sanchez David RY, Chauveau L, Jouvenet N, Markowitz M, van der Werf S, Schwartz O, Tangy F, Bhardwaj N, Greenbaum BD, Komarova AV
iScience 2022 Jul 15;25(7):104599
iScience 2022 Jul 15;25(7):104599
Novel autoantibodies identified in ACPA-negative rheumatoid arthritis.
Li K, Mo W, Wu L, Wu X, Luo C, Xiao X, Jia X, Yang H, Fei Y, Chen H, Zhang F, Li Y, Zhao L, Zhang X
Annals of the rheumatic diseases 2021 Jun;80(6):739-747
Annals of the rheumatic diseases 2021 Jun;80(6):739-747
RIG-I like receptor sensing of host RNAs facilitates the cell-intrinsic immune response to KSHV infection.
Zhao Y, Ye X, Dunker W, Song Y, Karijolich J
Nature communications 2018 Nov 19;9(1):4841
Nature communications 2018 Nov 19;9(1):4841
RNA triphosphatase DUSP11 enables exonuclease XRN-mediated restriction of hepatitis C virus.
Kincaid RP, Lam VL, Chirayil RP, Randall G, Sullivan CS
Proceedings of the National Academy of Sciences of the United States of America 2018 Aug 7;115(32):8197-8202
Proceedings of the National Academy of Sciences of the United States of America 2018 Aug 7;115(32):8197-8202
DUSP11 - An RNA phosphatase that regulates host and viral non-coding RNAs in mammalian cells.
Burke JM, Sullivan CS
RNA biology 2017 Nov 2;14(11):1457-1465
RNA biology 2017 Nov 2;14(11):1457-1465
DUSP11 activity on triphosphorylated transcripts promotes Argonaute association with noncanonical viral microRNAs and regulates steady-state levels of cellular noncoding RNAs.
Burke JM, Kincaid RP, Nottingham RM, Lambowitz AM, Sullivan CS
Genes & development 2016 Sep 15;30(18):2076-2092
Genes & development 2016 Sep 15;30(18):2076-2092
Isolation and characterization of DUSP11, a novel p53 target gene.
Caprara G, Zamponi R, Melixetian M, Helin K
Journal of cellular and molecular medicine 2009 Aug;13(8B):2158-2170
Journal of cellular and molecular medicine 2009 Aug;13(8B):2158-2170
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- A431 cells were subjected to SDS PAGE followed by western blot with 10204-2-AP(DUSP11 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunofluorescent analysis of HepG2 cells, using DUSP11 antibody 10204-2-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line