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- Antibody Data
- Antigen structure
- References [224]
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- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
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- Product number
- 10866-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10866-1-AP, RRID:AB_2257153
- Product name
- VDAC1/2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated VDAC1/2 antibody (Cat. #10866-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
Submitted references Effects of local skeletal muscle cooling prior to acute exercise and endurance training on mitochondrial adaptation in mice.
STIM1-containing contact sites promote direct calcium flux from the endoplasmic reticulum to mitochondria.
GIPC1 governed ferroptosis by regulating DECR1-modulating lipid homeostasis during dilated cardiomyopathy (DCM).
Aerobic exercise improve physical endurance and muscle function by ameliorating oxidative stress and modulating mitochondrial dynamics in aged skeletal muscle.
The Berberine Derivative BBR684 Inhibits VDAC Oligomerization to Suppress Ferroptosis in Acute Kidney Injury.
Super enhancer-driven LINC01013 mediates hypoxia-induced mitochondrial dysfunction by HSPA9 to determine pulmonary arterial smooth muscle cell fate.
Astaxanthin improves myogenicity of aged skeletal muscle progenitor cells in a sexually dimorphic manner.
Prepuberty exposure to polystyrene nanoplastics induces cardiac inflammation through calcium overload-mediated ROS/JAK1/STAT3 signaling cascade.
TRPV2 regulates cell fate in the human granulosa-like tumor cell line KGN: implications for granulosa cell tumors and cannabidiol.
Inhibition of voltage-dependent anion channel 1 aggregation protects pancreatic beta-cell mitochondria from glucose toxicity.
Lysosomal dysfunction contributes to lead (Pb) and high-fat diet (HFD)-induced neuronal apoptosis: A link with cathepsin B.
A method for isolating and cryopreserving intact mitochondria with improved integrity and functionality.
Metformin improves intestinal ischemia-reperfusion injury by reducing the formation of mitochondrial associated endoplasmic reticulum membranes (MAMs) and inhibiting ferroptosis in intestinal cells.
Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP(+)-induced neurological damage in the cellular model of Parkinson's disease.
Downregulation of EB1 impedes Cx43 localization and cardiac conduction after hypothermic ischemia-reperfusion in rats.
PLEKHF1 Induces Mitochondrial Dysfunction to Inhibit Osteosarcoma Growth and Metastasis.
Targeting Dlat-Trpv3 pathway by hyperforin elicits non-canonical promotion of adipose thermogenesis as an effective anti-obesity strategy.
Inhibiting SSBP1 enhances ferroptosis and improves the effectiveness of sorafenib treatment for liver cancer.
Sevoflurane preconditioning improves Cx43 localization and electrical conduction by stabilizing myocardial microtubule structure during ischemia-reperfusion.
Gestational zearalenone causes fetal intrauterine growth restriction partially through deriving ROS-Drp1 mediated placental PANoptosis.
Parkin modulates the hepatocellular carcinoma microenvironment by regulating PD-1/PD-L1 signalling.
IRE1α translational suppression potentiates STING-dependent chemoresistance in pancreatic cancer.
Polydopamine as a biocompatible and precise mitochondrial targeted therapeutic platform for reversing myocardial ischemia-reperfusion injury.
Kindlin-1 promotes mitophagy by inhibiting PINK1 degradation to enhance hepatocellular carcinoma progression and modulates sensitivity to donafenib.
Methionine is an essential amino acid in doxorubicin-induced cardiotoxicity through modulating mitophagy.
The ROS Mediates MCUb in Mitochondria-Regulated Apoptosis of TM4 Cells Induced by Titanium Dioxide Nanoparticles.
Mitochondrial Ferritin Overexpression Attenuates Ferroptosis and Mitochondrial Dysfunction by Reducing VDAC1 to Relieve MI/RI-Induced Damage.
Mitochondria-localized MBD2c facilitates mtDNA transcription and drug resistance.
Sculponeatin A induces mitochondrial dysfunction in non-small cell lung cancer through WWP2-mediated degradation of mitochondrial STAT3.
PA1b-like peptides alleviate mitochondrial dysfunction induced by glucose toxicity through interaction with VDAC1 in β-cells.
Marsdenia tenacissima extract accelerates ferroptosis of osteosarcoma cells by upregulating HO-1 and activating mitophagy.
OTUD1 exacerbates sepsis-associated encephalopathy by promoting HK2 mitochondrial release to drive microglia pyroptosis.
S-COS-Se mitigates cadmium-induced oxidative stress, inflammation, and immunotoxicity by restoring immune balance and inhibiting mitochondria-pyroptosis crosstalk.
Impaired Iron-Sulfur Cluster Synthesis Induces Mitochondrial PARthanatos in Diabetic Cardiomyopathy.
Characteristics of different lipid droplet-mitochondrial contacts patterns during lipid droplet metabolism in T2DM-induced MASLD.
Olesoxime protects against cisplatin-induced acute kidney injury by attenuating mitochondrial dysfunction.
Glucose-6-phosphate dehydrogenase regulates mitophagy by maintaining PINK1 stability.
Targeting PGAM5 attenuates airway inflammation in asthma by inhibiting HMGB1 release in bronchial epithelium.
Daurisoline inhibits glycolysis of lung cancer by targeting the AKT-HK2 axis.
BMP10 attenuates age-related atrial fibrillation susceptibility through improving mitochondrial function in atrial cardiomyocytes.
Metformin Ameliorates Early Brain Injury After Subarachnoid Hemorrhage Via Improving Endoplasmic Reticulum Stress and Mitochondrial Stress-Mediated Ca(2+) Imbalance.
Mitochondrial protease ClpP deficiency protects against tubulointerstitial damage in diabetic kidney disease.
VAMP4 in hypoxic adipose stem cell exosomes alleviates ischemia-reperfusion injury.
High matrix stiffness triggers the YAP-OPA1-TET1/3 loop to drive chemoresistance via enhanced nuclear-mitochondrial communication.
Diminution of HSP75 disrupts intestinal epithelial barrier by inciting mPTP opening in ulcerative colitis.
Mitochondrial respiratory complex IV deficiency recapitulates amyotrophic lateral sclerosis.
The African swine fever virus gene MGF_360-4L inhibits interferon signaling by recruiting mitochondrial selective autophagy receptor SQSTM1 degrading MDA5 antagonizing innate immune responses.
In vitro study on the promotion of osteogenic differentiation by mitochondrial-derived vesicles through activation of inflammation and reprogramming of metabolic pathways.
Microvesicles carrying EV71 virions cross BBB through endocytic pathway to induce brain injury.
Effect of 1-DNJ on Oxidative Stress-Induced Apoptosis in Porcine Ovarian GCs Through Modulation of the PERK-ATF4/MFN2 Signaling Pathway.
Loss of MTX2 causes mitochondrial dysfunction, podocyte injury, nephrotic proteinuria and glomerulopathy in mice and patients.
Chronic Stress-induced Serotonin Impairs Intestinal Epithelial Cell Mitochondrial Biogenesis via the AMPK-PGC-1α Axis.
Mitochondrial rewiring with small-molecule drug-free nanoassemblies unleashes anticancer immunity.
Prophylactic Effects of Betaine on Depression and Anxiety Behaviors in Mice with Dextran Sulfate Sodium-Induced Colitis.
The tumor suppressor Parkin exerts anticancer effects through regulating mitochondrial GAPDH activity.
NAT10 inhibition promotes ac4C-dependent ferroptosis to counteract sorafenib resistance in nasopharyngeal carcinoma.
Resveratrol protects cardiomyocytes against ischemia/reperfusion-induced ferroptosis via inhibition of the VDAC1/GPX4 pathway.
Propionate promotes ferroptosis and apoptosis through mitophagy and ACSL4-mediated ferroptosis elicits anti-leukemia immunity.
Ubiquitinome Analysis Uncovers Alterations in Synaptic Proteins and Glucose Metabolism Enzymes in the Hippocampi of Adolescent Mice Following Cold Exposure.
Leucine Supplementation Prevents the Development of Skeletal Muscle Dysfunction in a Rat Model of HFpEF.
Redistribution of defective mitochondria-mediated dihydroorotate dehydrogenase imparts 5-fluorouracil resistance in colorectal cancer.
Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets.
Peptide PDRPS6 attenuates myocardial ischemia injury by improving mitochondrial function.
Static magnetic field-modulated mesenchymal stem cell-derived mitochondria-containing microvesicles for enhanced intervertebral disc degeneration therapy.
A novel protein CYTB-187AA encoded by the mitochondrial gene CYTB modulates mammalian early development.
PGAM5 exacerbates acute renal injury by initiating mitochondria-dependent apoptosis by facilitating mitochondrial cytochrome c release.
Stress granules affect the dual PI3K/mTOR inhibitor response by regulating the mitochondrial unfolded protein response.
Interactome Analysis Identifies the Role of BZW2 in Promoting Endoplasmic Reticulum-Mitochondria Contact and Mitochondrial Metabolism.
Effects of metformin on glucose metabolism and mitochondrial function in patients with obstructive sleep apnea: A pilot randomized trial.
OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB.
Particulate matter induced cognitive impairments via endoplasmic reticulum stress-mediated damage to mitochondria-associated endoplasmic reticulum membranes in immature rats.
Mitochondrial HKDC1 suppresses oxidative stress and apoptosis by regulating mitochondrial function in goose fatty liver.
Puerarin Protects Myocardium From Ischaemia/Reperfusion Injury by Inhibiting Ferroptosis Through Downregulation of VDAC1.
LARP1, an RNA-binding protein, participates in ovarian cancer cell survival by regulating mitochondrial oxidative phosphorylation in response to the influence of the PI3K/mTOR pathway.
SUCNR 1 promotes atherosclerosis by inducing endoplasmic reticulum stress mediated ER-mito crosstalk.
BRD7 regulates cellular senescence and apoptosis in ALS by modulating p21 expression and p53 mitochondrial translocation respectively.
Non-transgenic guinea pig strains exhibit divergent age-related changes in hippocampal mitochondrial respiration.
Unmasking Protein Phosphatase 2A Regulatory Subunit B as a Crucial Factor in the Progression of Dilated Cardiomyopathy.
Cytarabine prevents neuronal damage by enhancing AMPK to stimulate PINK1 / Parkin-involved mitophagy in Parkinson's disease model.
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Sex differences in the neuronal transcriptome and synaptic mitochondrial function in the cerebral cortex of a multiple sclerosis model.
Reduced ER-mitochondrial contact sites and mitochondrial Ca(2+) flux in PRKN-mutant patient tyrosine hydroxylase reporter iPSC lines.
PCSK9 Promotes Hypoxia-Induced EC Pyroptosis by Regulating Smac Mitochondrion-Cytoplasm Translocation in Critical Limb Ischemia.
Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer.
Heterogeneity of perivascular astrocyte endfeet depending on vascular regions in the mouse brain.
Longitudinal diffusion barriers imposed by myofilaments and mitochondria in murine cardiac myocytes.
ER-associated degradation in cystinosis pathogenesis and the prospects of precision medicine.
The poxvirus F17 protein counteracts mitochondrially orchestrated antiviral responses.
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
Mitochondrial Methionyl-tRNA Formyltransferase Deficiency Alleviates Metaflammation by Modulating Mitochondrial Activity in Mice.
Inhibiting NLRP3 Inflammasome Activation by CY-09 Helps to Restore Cerebral Glucose Metabolism in 3×Tg-AD Mice.
Exercise protects aged mice against coronary endothelial senescence via FUNDC1-dependent mitophagy.
Artesunate protects against ocular fibrosis by suppressing fibroblast activation and inducing mitochondria-dependent ferroptosis.
Sodium houttuyfonate exerts its neuroprotection effect by inhibiting the M1 microglia polarization in a TLR4/NF-κB signal pathway.
SCP2 mediates the transport of lipid hydroperoxides to mitochondria in chondrocyte ferroptosis.
Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal.
QKI shuttles internal m(7)G-modified transcripts into stress granules and modulates mRNA metabolism.
Oligomeric CHMP7 mediates three-way ER junctions and ER-mitochondria interactions.
Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax.
Effects of dapagliflozin monotherapy and combined aerobic exercise on skeletal muscle mitochondrial quality control and insulin resistance in type 2 diabetes mellitus rats.
High Sucrose Diet-Induced Subunit I Tyrosine 304 Phosphorylation of Cytochrome c Oxidase Leads to Liver Mitochondrial Respiratory Dysfunction in the Cohen Diabetic Rat Model.
Guf1 overexpression improves pancreatic β cell functions in type 2 diabetes mellitus rats with Roux-en-Y gastric bypass (RYGB) surgery.
The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy.
CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth.
ATF5 regulates tubulointerstitial injury in diabetic kidney disease via mitochondrial unfolded protein response.
MLN2238 exerts its anti-tumor effects via regulating ROS/JNK/mitochondrial signaling pathways in intrahepatic cholangiocarcinoma.
Transient Receptor Potential Vanilloid Type 1 Protects Against Pressure Overload-Induced Cardiac Hypertrophy by Promoting Mitochondria-Associated Endoplasmic Reticulum Membranes.
Paternal cadmium exposure affects testosterone synthesis by reducing the testicular cholesterol pool in offspring mice.
The Endoplasmic Reticulum ATP13A1 is Essential for MAVS-Mediated Antiviral Innate Immunity.
Acyl-CoA thioesterase 9 promotes tumour growth and metastasis through reprogramming of fatty acid metabolism in hepatocellular carcinoma.
Cadmium-induced apoptosis of Leydig cells is mediated by excessive mitochondrial fission and inhibition of mitophagy.
Salidroside reduces neuropathology in Alzheimer's disease models by targeting NRF2/SIRT3 pathway.
COX7A1 enhances the sensitivity of human NSCLC cells to cystine deprivation-induced ferroptosis via regulating mitochondrial metabolism.
Triacetyl Resveratrol Inhibits PEDV by Inducing the Early Apoptosis In Vitro.
O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.
Repeated social defeat stress inhibits development of hippocampus neurons through mitophagy and autophagy.
PFKP alleviates glucose starvation-induced metabolic stress in lung cancer cells via AMPK-ACC2 dependent fatty acid oxidation.
Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults.
A novel polyethylene glycol (PEG)-drug conjugate of Venetoclax, a Bcl-2 inhibitor, for treatment of acute myeloid leukemia (AML).
C19orf12 ablation causes ferroptosis in mitochondrial membrane protein-associated with neurodegeneration.
Inhibition of Fatty Acid Translocase (FAT/CD36) Palmitoylation Enhances Hepatic Fatty Acid β-Oxidation by Increasing Its Localization to Mitochondria and Interaction with Long-Chain Acyl-CoA Synthetase 1.
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.
Ruthenium 360 and mitoxantrone inhibit mitochondrial calcium uniporter channel to prevent liver steatosis induced by high-fat diet.
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Maternal Herpesviridae infection during pregnancy alters midbrain dopaminergic signatures in adult offspring.
Epigallocatechin-3-gallate exerts cardioprotective effects related to energy metabolism in pressure overload-induced cardiac dysfunction.
Mitochondrial PKM2 deacetylation by procyanidin B2-induced SIRT3 upregulation alleviates lung ischemia/reperfusion injury.
Identification of a novel native peptide derived from 60S ribosomal protein L23a that translationally regulates p53 to reduce myocardial ischemia-reperfusion.
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy.
Characterization of lncRNA functioning in ovine conceptuses and endometria during the peri-implantation period.
PACS2-TRPV1 axis is required for ER-mitochondrial tethering during ER stress and lung fibrosis.
Myricetin Restores Aβ-Induced Mitochondrial Impairments in N2a-SW Cells.
Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy.
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP().
TRPML1-induced autophagy inhibition triggers mitochondrial mediated apoptosis.
Downregulating MFN2 Promotes the Differentiation of Induced Pluripotent Stem Cells into Mesenchymal Stem Cells through the PI3K/Akt/GSK-3β/Wnt Signaling Pathway.
MFN2 knockdown promotes osteogenic differentiation of iPSC-MSCs through aerobic glycolysis mediated by the Wnt/β-catenin signaling pathway.
Differential Expression Profiles and Potential Intergenerational Functions of tRNA-Derived Small RNAs in Mice After Cadmium Exposure.
Cardioprotective Role of SIRT5 in Response to Acute Ischemia Through a Novel Liver-Cardiac Crosstalk Mechanism.
CRMP2 Is Involved in Regulation of Mitochondrial Morphology and Motility in Neurons.
NAD(+) Repletion Reverses Heart Failure With Preserved Ejection Fraction.
8a, a New Acridine Antiproliferative and Pro-Apoptotic Agent Targeting HDAC1/DNMT1.
High Dietary Fat Consumption Impairs Axonal Mitochondrial Function In Vivo.
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis.
Walnut-Derived Peptide Activates PINK1 via the NRF2/KEAP1/HO-1 Pathway, Promotes Mitophagy, and Alleviates Learning and Memory Impairments in a Mice Model.
Novel NDUFA12 variants are associated with isolated complex I defect and variable clinical manifestation.
Sulforaphane Balances Ca(2+) Homeostasis Injured by Excessive Fat via Mitochondria-Associated Membrane (MAM).
Tubular Mas receptor mediates lipid-induced kidney injury.
Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line.
Novel selective hexokinase 2 inhibitor Benitrobenrazide blocks cancer cells growth by targeting glycolysis.
The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
Gelsolin Governs the Neuroendocrine Transdifferentiation of Prostate Cancer Cells and Suppresses the Apoptotic Machinery.
DDAH2 suppresses RLR-MAVS-mediated innate antiviral immunity by stimulating nitric oxide-activated, Drp1-induced mitochondrial fission.
Citicoline Protects Auditory Hair Cells Against Neomycin-Induced Damage.
Maternally Inherited Diabetes Mellitus Associated with a Novel m.15897G>A Mutation in Mitochondrial tRNA(Thr) Gene.
Complex I mutations synergize to worsen the phenotypic expression of Leber's hereditary optic neuropathy.
miR-103a-3p regulates mitophagy in Parkinson's disease through Parkin/Ambra1 signaling.
Mutant huntingtin does not cross the mitochondrial outer membrane.
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.
Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis.
Icariin protects human nucleus pulposus cells from hydrogen peroxide-induced mitochondria-mediated apoptosis by activating nuclear factor erythroid 2-related factor 2.
Activation of CaMKII via ER-stress mediates coxsackievirus B3-induced cardiomyocyte apoptosis.
NIPA2 regulates osteoblast function by modulating mitophagy in type 2 diabetes osteoporosis.
Estrogen receptors participate in silibinin-caused nuclear translocation of apoptosis-inducing factor in human breast cancer MCF-7 cells.
p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.
Spermidine Prevents Heart Injury in Neonatal Rats Exposed to Intrauterine Hypoxia by Inhibiting Oxidative Stress and Mitochondrial Fragmentation.
Corilagin Alleviates Nonalcoholic Fatty Liver Disease in High-Fat Diet-Induced C57BL/6 Mice by Ameliorating Oxidative Stress and Restoring Autophagic Flux.
Decreased expression of apoptosis-inducing factor in renal cell carcinoma is associated with poor prognosis and reduced postoperative survival.
Mapping Interactome Networks of DNAJC11, a Novel Mitochondrial Protein Causing Neuromuscular Pathology in Mice.
A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.
The Otubain YOD1 Suppresses Aggregation and Activation of the Signaling Adaptor MAVS through Lys63-Linked Deubiquitination.
Contribution of mitochondrial ND1 3394T>C mutation to the phenotypic manifestation of Leber's hereditary optic neuropathy.
Deletion of Gtpbp3 in zebrafish revealed the hypertrophic cardiomyopathy manifested by aberrant mitochondrial tRNA metabolism.
A Multidimensional Characterization of E3 Ubiquitin Ligase and Substrate Interaction Network.
JNK activation-mediated nuclear SIRT1 protein suppression contributes to silica nanoparticle-induced pulmonary damage via p53 acetylation and cytoplasmic localisation.
Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.
Autophagy Attenuation Hampers Progesterone Synthesis during the Development of Pregnant Corpus Luteum.
Contribution of a mitochondrial tyrosyl-tRNA synthetase mutation to the phenotypic expression of the deafness-associated tRNA(Ser(UCN)) 7511A>G mutation.
A novel iron(II) phenanthroline complex exhibits anticancer activity against TFR1-overexpressing esophageal squamous cell carcinoma cells through ROS accumulation and DNA damage.
Mitochondrial NOS1 suppresses apoptosis in colon cancer cells through increasing SIRT3 activity.
Silibinin-induced apoptosis of breast cancer cells involves mitochondrial impairment.
Mitochondrial dynamics and preconditioning in white matter.
Distinctive Structural and Molecular Features of Myelinated Inhibitory Axons in Human Neocortex.
Protective effects of mitochondrion-targeted peptide SS-31 against hind limb ischemia-reperfusion injury.
Picroside II Exerts a Neuroprotective Effect by Inhibiting mPTP Permeability and EndoG Release after Cerebral Ischemia/Reperfusion Injury in Rats.
Metabolic and chemical regulation of tRNA modification associated with taurine deficiency and human disease.
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Exogenous H(2)S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice.
Leukoencephalopathy due to Complex II Deficiency and Bi-Allelic SDHB Mutations: Further Cases and Implications for Genetic Counselling.
Esculetin exerts antitumor effect on human gastric cancer cells through IGF-1/PI3K/Akt signaling pathway.
Esculetin induces apoptosis of SMMC-7721 cells through IGF-1/PI3K/Akt-mediated mitochondrial pathways.
DJ-1 modulates mitochondrial response to oxidative stress: clues from a novel diagnosis of PARK7.
Quinocetone induces mitochondrial apoptosis in HepG2 cells through ROS-dependent promotion of VDAC1 oligomerization and suppression of Wnt1/β-catenin signaling pathway.
Methyl jasmonate leads to necrosis and apoptosis in hepatocellular carcinoma cells via inhibition of glycolysis and represses tumor growth in mice.
Upregulation of Spinal Voltage-Dependent Anion Channel 1 Contributes to Bone Cancer Pain Hypersensitivity in Rats.
A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.
Inhibition of p66Shc-mediated mitochondrial apoptosis via targeting prolyl-isomerase Pin1 attenuates intestinal ischemia/reperfusion injury in rats.
Exercise Intolerance and Myoglobinuria Associated with a Novel Maternally Inherited MT-ND1 Mutation.
Induction of Apoptosis by the Nonstructural Protein 4 and 10 of Porcine Reproductive and Respiratory Syndrome Virus.
Non-cytotoxic concentrations of acetaminophen induced mitochondrial biogenesis and antioxidant response in HepG2 cells.
Synergistic inhibition of sunitinib and ethaselen against human colorectal cancer cells proliferation.
Altered redox mitochondrial biology in the neurodegenerative disorder fragile X-tremor/ataxia syndrome: use of antioxidants in precision medicine.
Subcellular localization of DJ-1 in human HL-60 leukemia cells in response to diallyl disulfide treatment.
Proteomics-based identification of VDAC1 as a tumor promoter in cervical carcinoma.
Phosphatase and tensin homologue (PTEN)-induced putative kinase 1 reduces pancreatic β-cells apoptosis in glucotoxicity through activation of autophagy.
Sepsis-induced brain mitochondrial dysfunction is associated with altered mitochondrial Src and PTP1B levels.
α-Enolase plays a catalytically independent role in doxorubicin-induced cardiomyocyte apoptosis and mitochondrial dysfunction.
CLPB variants associated with autosomal-recessive mitochondrial disorder with cataract, neutropenia, epilepsy, and methylglutaconic aciduria.
O-Alkylated derivatives of quercetin induce apoptosis of MCF-7 cells via a caspase-independent mitochondrial pathway.
The self-interaction of a nodavirus replicase is enhanced by mitochondrial membrane lipids.
The mitochondrial thioredoxin is required for liver development in zebrafish.
Blockade of PKCβ protects against remote organ injury induced by intestinal ischemia and reperfusion via a p66shc-mediated mitochondrial apoptotic pathway.
Novel distribution of calreticulin to cardiomyocyte mitochondria and its increase in a rat model of dilated cardiomyopathy.
Mitochondrial binding of α-enolase stabilizes mitochondrial membrane: its role in doxorubicin-induced cardiomyocyte apoptosis.
Inhibition of VDAC1 prevents Ca²⁺-mediated oxidative stress and apoptosis induced by 5-aminolevulinic acid mediated sonodynamic therapy in THP-1 macrophages.
Proteomic study reveals a co-occurrence of gallic acid-induced apoptosis and glycolysis in B16F10 melanoma cells.
Membrane association of Wuhan nodavirus protein A is required for its ability to accumulate genomic RNA1 template.
Distinct mechanisms of axonal globule formation in mice expressing human wild type α-synuclein or dementia with Lewy bodies-linked P123H β-synuclein.
Proteomic profiling of the 11-dehydrosinulariolide-treated oral carcinoma cells Ca9-22: effects on the cell apoptosis through mitochondrial-related and ER stress pathway.
Mitochondrial nitric oxide synthase participates in septic shock myocardial depression by nitric oxide overproduction and mitochondrial permeability transition pore opening.
Proteomic investigation of anti-tumor activities exerted by sinularin against A2058 melanoma cells.
Kano R, Kusano T, Ando T, Takeda R, Natsuyama R, Takagi R, Poole DC, Kano Y, Hoshino D
The journal of physiological sciences : JPS 2026 Mar;76(1):100059
The journal of physiological sciences : JPS 2026 Mar;76(1):100059
STIM1-containing contact sites promote direct calcium flux from the endoplasmic reticulum to mitochondria.
Orantos-Aguilera Y, Sanchez-Lopez I, Pascual-Caro C, Gómez-Suaga P, Area-Gomez E, Pozo-Guisado E, Montesinos J, Martin-Romero FJ
The EMBO journal 2026 Mar;45(5):1760-1793
The EMBO journal 2026 Mar;45(5):1760-1793
GIPC1 governed ferroptosis by regulating DECR1-modulating lipid homeostasis during dilated cardiomyopathy (DCM).
Tang N, Mu R, Wang H, Wu J, Zhang J, Huang D, Han Y, Li W, Chen Y, Li X, Sun Y, Zhang Z, Zuo J, Hu Y, Yin Y, Qu Y, Liu J, Jiao L, Liu X, Liang H, Wang N, Bai Y, Liu Y, Wang B, Zhao D, Liu Y, Yang B
Cell death and differentiation 2026 Mar 5;
Cell death and differentiation 2026 Mar 5;
Aerobic exercise improve physical endurance and muscle function by ameliorating oxidative stress and modulating mitochondrial dynamics in aged skeletal muscle.
Zheng F, Zhou J, Cao Y, Lin L, Wang W, Zhang L, Li W, Li T, Wang L
Journal of physiology and biochemistry 2026 Mar 17;82(1)
Journal of physiology and biochemistry 2026 Mar 17;82(1)
The Berberine Derivative BBR684 Inhibits VDAC Oligomerization to Suppress Ferroptosis in Acute Kidney Injury.
Jiang Z, Zhang W, Zhu J, Wang C, Chen G, Guo Y
Current therapeutic research, clinical and experimental 2026 Jun;104:100825
Current therapeutic research, clinical and experimental 2026 Jun;104:100825
Super enhancer-driven LINC01013 mediates hypoxia-induced mitochondrial dysfunction by HSPA9 to determine pulmonary arterial smooth muscle cell fate.
Ma C, Wang Z, Zhu X, Pang X, Zhang L, Ou L, Chen Y, Liu Y, Mei J, Guan X, Meng Z, Tang Y, Zhang Z, Li B, Wen S, Shen A, Wang X
Cellular and molecular life sciences : CMLS 2026 Jan 6;83(1):57
Cellular and molecular life sciences : CMLS 2026 Jan 6;83(1):57
Astaxanthin improves myogenicity of aged skeletal muscle progenitor cells in a sexually dimorphic manner.
Clemens Z, Kosaraju J, Weaver L, Lasher C, Zhang J, Hecht K, Wang K, Bean AC, Sahu A
npj aging 2026 Jan 10;12(1):26
npj aging 2026 Jan 10;12(1):26
Prepuberty exposure to polystyrene nanoplastics induces cardiac inflammation through calcium overload-mediated ROS/JAK1/STAT3 signaling cascade.
Liu W, Liu Y, Shi J, Li J, Li G, Quan J, Zhao W
Free radical biology & medicine 2026 Feb 16;244:133-146
Free radical biology & medicine 2026 Feb 16;244:133-146
TRPV2 regulates cell fate in the human granulosa-like tumor cell line KGN: implications for granulosa cell tumors and cannabidiol.
Eubler K, Jeevanandan SP, Caban KM, Stöckl JB, Braun MB, Herrmann C, Schneider M, Kreitmair N, Scholz L, Mayr D, Renkawitz J, Welter H, Müller-Taubenberger A, Fröhlich T, Mayerhofer A
Cell communication and signaling : CCS 2026 Feb 12;24(1)
Cell communication and signaling : CCS 2026 Feb 12;24(1)
Inhibition of voltage-dependent anion channel 1 aggregation protects pancreatic beta-cell mitochondria from glucose toxicity.
Yao C, Zeng X, Huang S, Cheng H, Huang H, Zou Z, Mou B, Youssef M, Liu M, Wei Y, Liu J, Li H, Xiong Q, Shang X
International journal of biological macromolecules 2026 Apr;356:151598
International journal of biological macromolecules 2026 Apr;356:151598
Lysosomal dysfunction contributes to lead (Pb) and high-fat diet (HFD)-induced neuronal apoptosis: A link with cathepsin B.
Yuan Y, Liu M, Zhai M, Wu M, Zhang W, Xin Y, Ba Y, Zhang Y, Han L, Gao L, Huang H
Neurotoxicology 2026 Apr 28;114:103462
Neurotoxicology 2026 Apr 28;114:103462
A method for isolating and cryopreserving intact mitochondria with improved integrity and functionality.
Okutani A, Naima J, Ogihara A, Motoichi T, Ohsawa I, Ohta Y
Biophysics and physicobiology 2025;22(2):e220012
Biophysics and physicobiology 2025;22(2):e220012
Metformin improves intestinal ischemia-reperfusion injury by reducing the formation of mitochondrial associated endoplasmic reticulum membranes (MAMs) and inhibiting ferroptosis in intestinal cells.
Zhao X, Yan L, Tian L, Zhang X, Liu R, Li Z
Frontiers in pharmacology 2025;16:1581085
Frontiers in pharmacology 2025;16:1581085
Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP(+)-induced neurological damage in the cellular model of Parkinson's disease.
Zhang C, Huang P, Cheng H, Yuan X, Zhou M, Liu Y, Liu T, Chen D, Xu Q, Cai J
Frontiers in pharmacology 2025;16:1509317
Frontiers in pharmacology 2025;16:1509317
Downregulation of EB1 impedes Cx43 localization and cardiac conduction after hypothermic ischemia-reperfusion in rats.
Wen C, Yang R, Yi J, Cao Y, Song Y, An L, Wang Z, Gao H
PeerJ 2025;13:e19276
PeerJ 2025;13:e19276
PLEKHF1 Induces Mitochondrial Dysfunction to Inhibit Osteosarcoma Growth and Metastasis.
Wan J, Cai X, Liao Z, Liu Y, Liu Q, Zhang C, Long F
IUBMB life 2025 Sep;77(9):e70048
IUBMB life 2025 Sep;77(9):e70048
Targeting Dlat-Trpv3 pathway by hyperforin elicits non-canonical promotion of adipose thermogenesis as an effective anti-obesity strategy.
Lu S, Jiang Q, Zhou P, Yin L, Wang N, Xu J, Qian Q, Tao M, Yin H, Han L, Gu Y, Gao F, Liu J, Chen S
Journal of advanced research 2025 Sep;75:793-809
Journal of advanced research 2025 Sep;75:793-809
Inhibiting SSBP1 enhances ferroptosis and improves the effectiveness of sorafenib treatment for liver cancer.
Li S, Yang X, Gao H, Hu X, Wang D, Zhang Q, Xu J, Zhang J, Zhu L, Wang Z
International journal of oncology 2025 Sep;67(3)
International journal of oncology 2025 Sep;67(3)
Sevoflurane preconditioning improves Cx43 localization and electrical conduction by stabilizing myocardial microtubule structure during ischemia-reperfusion.
Yang R, Wen C, Wang Z, Gao H, Wang L, Zhou J, Wang T
Biochemical and biophysical research communications 2025 Sep 30;782:152552
Biochemical and biophysical research communications 2025 Sep 30;782:152552
Gestational zearalenone causes fetal intrauterine growth restriction partially through deriving ROS-Drp1 mediated placental PANoptosis.
Liu JR, Wu FN, Lin S, Chen C, Liu Y, Fan JW, Hong Q, Chen YH
Ecotoxicology and environmental safety 2025 Sep 1;302:118636
Ecotoxicology and environmental safety 2025 Sep 1;302:118636
Parkin modulates the hepatocellular carcinoma microenvironment by regulating PD-1/PD-L1 signalling.
Ye G, Sun X, Li J, Pu M, Zhang J
Journal of advanced research 2025 Oct;76:731-744
Journal of advanced research 2025 Oct;76:731-744
IRE1α translational suppression potentiates STING-dependent chemoresistance in pancreatic cancer.
Luo Y, Sun M, Chang L, He Z, Zhou X, Yuan Y, Sun H, Luo S, Huang J, Wu H, Liu W, Zhou Z, Mao Y, Ji Y, Liang T
Cell death & disease 2025 Oct 6;16(1):680
Cell death & disease 2025 Oct 6;16(1):680
Polydopamine as a biocompatible and precise mitochondrial targeted therapeutic platform for reversing myocardial ischemia-reperfusion injury.
Zhao T, Huang Y, Chen W, Qi W, Wang J, Xia Y, Zhou J, Long X, Nan Y, Huang Q, Ai K
Bioactive materials 2025 Nov;53:908-931
Bioactive materials 2025 Nov;53:908-931
Kindlin-1 promotes mitophagy by inhibiting PINK1 degradation to enhance hepatocellular carcinoma progression and modulates sensitivity to donafenib.
Ma H, Ou G, Wu B, Ding H, Zhang Y, Xia F, Shen Z, Zhao K, Chen C, Wu L, Lei J, Xu Y, Zhao X, Cao K, Li H
Cellular signalling 2025 Nov;135:112032
Cellular signalling 2025 Nov;135:112032
Methionine is an essential amino acid in doxorubicin-induced cardiotoxicity through modulating mitophagy.
Xin Y, Zhang Y, Yuan Z, Li S
Free radical biology & medicine 2025 May;232:28-39
Free radical biology & medicine 2025 May;232:28-39
The ROS Mediates MCUb in Mitochondria-Regulated Apoptosis of TM4 Cells Induced by Titanium Dioxide Nanoparticles.
Sun C, Wang Q, Li P, Dong R, Lei Y, Hu Y, Yan Y, Song G
Biological trace element research 2025 May;203(5):2760-2775
Biological trace element research 2025 May;203(5):2760-2775
Mitochondrial Ferritin Overexpression Attenuates Ferroptosis and Mitochondrial Dysfunction by Reducing VDAC1 to Relieve MI/RI-Induced Damage.
Yuan Y, Wang X, Xu H, Liu L, Liu J, Lai S, Huang H
Journal of cellular and molecular medicine 2025 Jun;29(12):e70650
Journal of cellular and molecular medicine 2025 Jun;29(12):e70650
Mitochondria-localized MBD2c facilitates mtDNA transcription and drug resistance.
Hao Y, Zhou Z, Liu R, Shen S, Liu H, Zhou Y, Sun Y, Mao Q, Zhang T, Li ST, Liu Z, Chu Y, Sun L, Gao P, Zhang H
Nature chemical biology 2025 Jun;21(6):926-938
Nature chemical biology 2025 Jun;21(6):926-938
Sculponeatin A induces mitochondrial dysfunction in non-small cell lung cancer through WWP2-mediated degradation of mitochondrial STAT3.
Wan F, Qian C, Liu X, Zhong Y, Peng W, Zhang L, Zhan X, Huang Y, Zhang C, Wang J, Si Y, Liu Y
British journal of pharmacology 2025 Jun;182(12):2662-2681
British journal of pharmacology 2025 Jun;182(12):2662-2681
PA1b-like peptides alleviate mitochondrial dysfunction induced by glucose toxicity through interaction with VDAC1 in β-cells.
Huang H, Zeng X, Zhang L, Cheng H, Hu K, Shang X, Yao C
Food & function 2025 Jun 3;16(11):4325-4342
Food & function 2025 Jun 3;16(11):4325-4342
Marsdenia tenacissima extract accelerates ferroptosis of osteosarcoma cells by upregulating HO-1 and activating mitophagy.
Xiang D, Zhang X, Xue X, Liang H, Meng J, Zhao S, Yang J, Zhou Y, Hu Y, Xu L, Shi M, Zhang J, Wang M, Chen J, Han Y
Journal of ethnopharmacology 2025 Jun 26;350:120055
Journal of ethnopharmacology 2025 Jun 26;350:120055
OTUD1 exacerbates sepsis-associated encephalopathy by promoting HK2 mitochondrial release to drive microglia pyroptosis.
Jing G, Gong H, Wang H, Zuo J, Wu D, Liu H, Wang X, Yuan M, Xia Y, Du T, Liu W, Wu X, Song X
Journal of neuroinflammation 2025 Jun 11;22(1):154
Journal of neuroinflammation 2025 Jun 11;22(1):154
S-COS-Se mitigates cadmium-induced oxidative stress, inflammation, and immunotoxicity by restoring immune balance and inhibiting mitochondria-pyroptosis crosstalk.
Zheng H, Dong W, Qiu H, Gao S, Hou L, Dong J, Zhao P, Chen F
Ecotoxicology and environmental safety 2025 Jul 15;300:118462
Ecotoxicology and environmental safety 2025 Jul 15;300:118462
Impaired Iron-Sulfur Cluster Synthesis Induces Mitochondrial PARthanatos in Diabetic Cardiomyopathy.
Wang M, Zhang S, Tian J, Yang F, Chen H, Bai S, Kang J, Pang K, Huang J, Dong M, Dong S, Tian Z, Fang S, Fan H, Lu F, Yu B, Li S, Zhang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(1):e2406695
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(1):e2406695
Characteristics of different lipid droplet-mitochondrial contacts patterns during lipid droplet metabolism in T2DM-induced MASLD.
Xu Y, Zhang Y, Sun W, Tang Q, Feng W, Xiao H, Wang J, Yuan X, Xiang M, Gao Y, Zhang H, Lu J
Scientific reports 2025 Jan 27;15(1):3399
Scientific reports 2025 Jan 27;15(1):3399
Olesoxime protects against cisplatin-induced acute kidney injury by attenuating mitochondrial dysfunction.
Wang P, Ouyang J, Zhou K, Hu D, Zhang S, Zhang A, Yang Y
Biomedical journal 2025 Feb;48(1):100730
Biomedical journal 2025 Feb;48(1):100730
Glucose-6-phosphate dehydrogenase regulates mitophagy by maintaining PINK1 stability.
Cho YL, Tan HWS, Yang J, Kuah BZM, Lim NSY, Fu N, Bay BH, Ling SC, Shen HM
Life metabolism 2025 Feb;4(1):loae040
Life metabolism 2025 Feb;4(1):loae040
Targeting PGAM5 attenuates airway inflammation in asthma by inhibiting HMGB1 release in bronchial epithelium.
Zhang Q, Wu J, Lan Y, Wang Y, Chen M, Wang J, Zhao X, Liu L, Zhao W, Zhao H
Free radical biology & medicine 2025 Feb 16;228:207-220
Free radical biology & medicine 2025 Feb 16;228:207-220
Daurisoline inhibits glycolysis of lung cancer by targeting the AKT-HK2 axis.
Tan SM, Luo L, He YF, Li W, Wan XX
Cancer biology & therapy 2025 Dec;26(1):2442556
Cancer biology & therapy 2025 Dec;26(1):2442556
BMP10 attenuates age-related atrial fibrillation susceptibility through improving mitochondrial function in atrial cardiomyocytes.
Gao Q, Cao Y, Zhao X, Mu H, Li Y, Yuan Y
Archives of gerontology and geriatrics 2025 Dec;139:105997
Archives of gerontology and geriatrics 2025 Dec;139:105997
Metformin Ameliorates Early Brain Injury After Subarachnoid Hemorrhage Via Improving Endoplasmic Reticulum Stress and Mitochondrial Stress-Mediated Ca(2+) Imbalance.
Zhang Z, Zhang J, Li L, Zong L
Molecular neurobiology 2025 Dec 5;63(1):256
Molecular neurobiology 2025 Dec 5;63(1):256
Mitochondrial protease ClpP deficiency protects against tubulointerstitial damage in diabetic kidney disease.
Wang H, Liu Y, Liu J, Zhang S, Li X, Sun L, Liu F, Liu Y, Xiao L
International immunopharmacology 2025 Dec 3;166:115641
International immunopharmacology 2025 Dec 3;166:115641
VAMP4 in hypoxic adipose stem cell exosomes alleviates ischemia-reperfusion injury.
Wang Y, Yu S, Wang X, Jin R, Liu F, Yang J
Cellular and molecular life sciences : CMLS 2025 Dec 29;83(1):8
Cellular and molecular life sciences : CMLS 2025 Dec 29;83(1):8
High matrix stiffness triggers the YAP-OPA1-TET1/3 loop to drive chemoresistance via enhanced nuclear-mitochondrial communication.
Wu P, Wang S, Hu Z, Zhang H, Lin Y, Li Z, Wu J, Chen Y, Chen Y, Xu Y, Li J, Guan Y
iScience 2025 Dec 19;28(12):113996
iScience 2025 Dec 19;28(12):113996
Diminution of HSP75 disrupts intestinal epithelial barrier by inciting mPTP opening in ulcerative colitis.
Liang H, Bai X, Zhu R, Song H, Miao Y, Wen Y, Niu J, Zhang F
Cellular signalling 2025 Aug;132:111837
Cellular signalling 2025 Aug;132:111837
Mitochondrial respiratory complex IV deficiency recapitulates amyotrophic lateral sclerosis.
Cheng M, Lu D, Li K, Wang Y, Tong X, Qi X, Yan C, Ji K, Wang J, Wang W, Lv H, Zhang X, Kong W, Zhang J, Ma J, Li K, Wang Y, Feng J, Wei P, Li Q, Shen C, Fu XD, Ma Y, Zhang X
Nature neuroscience 2025 Apr;28(4):748-756
Nature neuroscience 2025 Apr;28(4):748-756
The African swine fever virus gene MGF_360-4L inhibits interferon signaling by recruiting mitochondrial selective autophagy receptor SQSTM1 degrading MDA5 antagonizing innate immune responses.
Sun H, Yang J, Zhang Z, Wu M, Tian Z, Liu Y, Zhang X, Zhong J, Yang S, Chen Y, Luo J, Guan G, Yin H, Niu Q
mBio 2025 Apr 9;16(4):e0267724
mBio 2025 Apr 9;16(4):e0267724
In vitro study on the promotion of osteogenic differentiation by mitochondrial-derived vesicles through activation of inflammation and reprogramming of metabolic pathways.
Pan C, Cheng C, Zhong S, Li S, Tan W, Yao Y
Journal of orthopaedic surgery and research 2025 Apr 17;20(1):388
Journal of orthopaedic surgery and research 2025 Apr 17;20(1):388
Microvesicles carrying EV71 virions cross BBB through endocytic pathway to induce brain injury.
Tian X, Liu B, Li L, Yuan M, You Q, Zhang R, Chen D, Cheng M, Zheng N, He M, Wu Z
Cell communication and signaling : CCS 2025 Apr 14;23(1):183
Cell communication and signaling : CCS 2025 Apr 14;23(1):183
Effect of 1-DNJ on Oxidative Stress-Induced Apoptosis in Porcine Ovarian GCs Through Modulation of the PERK-ATF4/MFN2 Signaling Pathway.
Xing W, Li M, Wang B, Huo L, Tian W, Ge F, Shen M, Sun L, Liu J, Yu S
Antioxidants (Basel, Switzerland) 2025 Apr 11;14(4)
Antioxidants (Basel, Switzerland) 2025 Apr 11;14(4)
Loss of MTX2 causes mitochondrial dysfunction, podocyte injury, nephrotic proteinuria and glomerulopathy in mice and patients.
Li T, Bao Y, Xia Y, Meng H, Zhou C, Huang L, Wang X, Lai EY, Jiang P, Mao J
International journal of biological sciences 2024;20(3):937-952
International journal of biological sciences 2024;20(3):937-952
Chronic Stress-induced Serotonin Impairs Intestinal Epithelial Cell Mitochondrial Biogenesis via the AMPK-PGC-1α Axis.
Yang D, Sun Y, Wen P, Chen Y, Cao J, Sun X, Dong Y
International journal of biological sciences 2024;20(11):4476-4495
International journal of biological sciences 2024;20(11):4476-4495
Mitochondrial rewiring with small-molecule drug-free nanoassemblies unleashes anticancer immunity.
Ren L, Wan J, Li X, Yao J, Ma Y, Meng F, Zheng S, Han W, Wang H
Nature communications 2024 Sep 3;15(1):7664
Nature communications 2024 Sep 3;15(1):7664
Prophylactic Effects of Betaine on Depression and Anxiety Behaviors in Mice with Dextran Sulfate Sodium-Induced Colitis.
Liu W, Zhong X, Yi Y, Xie L, Zhou W, Cao W, Chen L
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21041-21051
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21041-21051
The tumor suppressor Parkin exerts anticancer effects through regulating mitochondrial GAPDH activity.
Sun X, Ye G, Li J, Yuan L, Bai G, Xu YJ, Zhang J
Oncogene 2024 Oct;43(44):3215-3226
Oncogene 2024 Oct;43(44):3215-3226
NAT10 inhibition promotes ac4C-dependent ferroptosis to counteract sorafenib resistance in nasopharyngeal carcinoma.
Xue Z, Xie H, Shan Y, Zhang L, Cheng L, Chen W, Zhu R, Zhang K, Ni H, Zhang Z, You Y, You B
Cancer science 2024 Oct;115(10):3256-3272
Cancer science 2024 Oct;115(10):3256-3272
Resveratrol protects cardiomyocytes against ischemia/reperfusion-induced ferroptosis via inhibition of the VDAC1/GPX4 pathway.
Hu T, Zou HX, Zhang ZY, Wang YC, Hu FJ, Huang WX, Liu JC, Lai SQ, Huang H
European journal of pharmacology 2024 May 15;971:176524
European journal of pharmacology 2024 May 15;971:176524
Propionate promotes ferroptosis and apoptosis through mitophagy and ACSL4-mediated ferroptosis elicits anti-leukemia immunity.
Wei Y, Liu W, Wang R, Chen Y, Liu J, Guo X, Can C, Yang X, Wang D, Hu X, Ma D
Free radical biology & medicine 2024 Mar;213:36-51
Free radical biology & medicine 2024 Mar;213:36-51
Ubiquitinome Analysis Uncovers Alterations in Synaptic Proteins and Glucose Metabolism Enzymes in the Hippocampi of Adolescent Mice Following Cold Exposure.
Li XY, Yin X, Lu JJ, Li QR, Xing WQ, Han Q, Ji H, Li SZ, Yang HM, Guo JR, Wang ZQ, Xu B
Cells 2024 Mar 25;13(7)
Cells 2024 Mar 25;13(7)
Leucine Supplementation Prevents the Development of Skeletal Muscle Dysfunction in a Rat Model of HFpEF.
Alves PKN, Schauer A, Augstein A, Prieto Jarabo ME, Männel A, Barthel P, Vahle B, Moriscot AS, Linke A, Adams V
Cells 2024 Mar 13;13(6)
Cells 2024 Mar 13;13(6)
Redistribution of defective mitochondria-mediated dihydroorotate dehydrogenase imparts 5-fluorouracil resistance in colorectal cancer.
Dong S, Zhang M, Cheng Z, Zhang X, Liang W, Li S, Li L, Xu Q, Song S, Liu Z, Yang G, Zhao X, Tao Z, Liang S, Wang K, Zhang G, Hu S
Redox biology 2024 Jul;73:103207
Redox biology 2024 Jul;73:103207
Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets.
Lu J, Liu G, Sun W, Jia G, Zhao H, Chen X, Wang J
The Journal of nutrition 2024 Jul;154(7):2087-2096
The Journal of nutrition 2024 Jul;154(7):2087-2096
Peptide PDRPS6 attenuates myocardial ischemia injury by improving mitochondrial function.
Feng M, Zhang L, Yin A, Zhang H, Wu X, Qian L
European journal of pharmacology 2024 Jul 5;974:176570
European journal of pharmacology 2024 Jul 5;974:176570
Static magnetic field-modulated mesenchymal stem cell-derived mitochondria-containing microvesicles for enhanced intervertebral disc degeneration therapy.
Shi P, Gao H, Cheng Z, Zhao K, Chen Y, Chen X, Gan W, Zhang A, Yang C, Zhang Y
Journal of nanobiotechnology 2024 Jul 31;22(1):457
Journal of nanobiotechnology 2024 Jul 31;22(1):457
A novel protein CYTB-187AA encoded by the mitochondrial gene CYTB modulates mammalian early development.
Hu Z, Yang L, Zhang M, Tang H, Huang Y, Su Y, Ding Y, Li C, Wang M, Zhou Y, Zhang Q, Guo L, Wu Y, Wang Q, Liu N, Kang H, Wu Y, Yao D, Li Y, Ruan Z, Wang H, Bao F, Liu G, Wang J, Wang Y, Wang W, Lu G, Qin D, Pei D, Chan WY, Liu X
Cell metabolism 2024 Jul 2;36(7):1586-1597.e7
Cell metabolism 2024 Jul 2;36(7):1586-1597.e7
PGAM5 exacerbates acute renal injury by initiating mitochondria-dependent apoptosis by facilitating mitochondrial cytochrome c release.
Li JY, Sun XA, Wang X, Yang NH, Xie HY, Guo HJ, Lu L, Xie X, Zhou L, Liu J, Zhang W, Lu LM
Acta pharmacologica Sinica 2024 Jan;45(1):125-136
Acta pharmacologica Sinica 2024 Jan;45(1):125-136
Stress granules affect the dual PI3K/mTOR inhibitor response by regulating the mitochondrial unfolded protein response.
Lin N, Sun L, Chai J, Qi H, Zhao Y, Ma J, Xia M, Hu X
Cancer cell international 2024 Jan 18;24(1):38
Cancer cell international 2024 Jan 18;24(1):38
Interactome Analysis Identifies the Role of BZW2 in Promoting Endoplasmic Reticulum-Mitochondria Contact and Mitochondrial Metabolism.
Maio G, Smith M, Bhawal R, Zhang S, Baskin JM, Li J, Lin H
Molecular & cellular proteomics : MCP 2024 Feb;23(2):100709
Molecular & cellular proteomics : MCP 2024 Feb;23(2):100709
Effects of metformin on glucose metabolism and mitochondrial function in patients with obstructive sleep apnea: A pilot randomized trial.
Zunica ERM, Heintz EC, Dantas WS, Hebert RC, Tanksley M, Beyl RA, Mader EC Jr, Kirwan JP, Axelrod CL, Singh P
Physiological reports 2024 Feb;12(3):e15948
Physiological reports 2024 Feb;12(3):e15948
OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB.
Ma W, Sun Y, Yan R, Zhang P, Shen S, Lu H, Zhou Z, Jiang Z, Ye L, Mao Q, Xiong N, Jia W, Sun L, Gao P, Zhang H
Molecular cell 2024 Feb 1;84(3):538-551.e7
Molecular cell 2024 Feb 1;84(3):538-551.e7
Particulate matter induced cognitive impairments via endoplasmic reticulum stress-mediated damage to mitochondria-associated endoplasmic reticulum membranes in immature rats.
Wang L, Gui J, Tian B, Ding R, Wang W, Jiang C, Zhang S, Zhang X, Liu J, Jiang L
Toxicology 2024 Dec;509:153979
Toxicology 2024 Dec;509:153979
Mitochondrial HKDC1 suppresses oxidative stress and apoptosis by regulating mitochondrial function in goose fatty liver.
Xing Y, Ge J, Wang Y, Zhou X, Yuan Z, Lv M, Zhao M, Liu L, Gong D, Geng T, Xie K
International journal of biological macromolecules 2024 Dec;282(Pt 4):137222
International journal of biological macromolecules 2024 Dec;282(Pt 4):137222
Puerarin Protects Myocardium From Ischaemia/Reperfusion Injury by Inhibiting Ferroptosis Through Downregulation of VDAC1.
Hu F, Hu T, He A, Yuan Y, Wang X, Zou C, Qiao Y, Xu H, Liu L, Wang Q, Liu J, Lai S, Huang H
Journal of cellular and molecular medicine 2024 Dec;28(24):e70313
Journal of cellular and molecular medicine 2024 Dec;28(24):e70313
LARP1, an RNA-binding protein, participates in ovarian cancer cell survival by regulating mitochondrial oxidative phosphorylation in response to the influence of the PI3K/mTOR pathway.
Ma J, Dong D, Qi H, Li J, Yu H, Hu X, Sun L, Shen L
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167453
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167453
SUCNR 1 promotes atherosclerosis by inducing endoplasmic reticulum stress mediated ER-mito crosstalk.
Yuan C, Yu B, Li L, Chen J, Qin W, Zhou Z, Su M, Wang D, Zhang Y, Wu Q, He C, Wei D
International immunopharmacology 2024 Dec 25;143(Pt 3):113510
International immunopharmacology 2024 Dec 25;143(Pt 3):113510
BRD7 regulates cellular senescence and apoptosis in ALS by modulating p21 expression and p53 mitochondrial translocation respectively.
Tan X, Su X, Wang Y, Liang W, Wang D, Huo D, Wang H, Qi Y, Zhang W, Han L, Zhang D, Wang M, Xu J, Feng H
Neuroscience 2024 Dec 17;563:51-62
Neuroscience 2024 Dec 17;563:51-62
Non-transgenic guinea pig strains exhibit divergent age-related changes in hippocampal mitochondrial respiration.
Walsh MA, Latham AS, Zhang Q, Jacobs RA, Musci RV, LaRocca TJ, Moreno JA, Santangelo KS, Hamilton KL
Acta physiologica (Oxford, England) 2024 Aug;240(8):e14185
Acta physiologica (Oxford, England) 2024 Aug;240(8):e14185
Unmasking Protein Phosphatase 2A Regulatory Subunit B as a Crucial Factor in the Progression of Dilated Cardiomyopathy.
Lin F, Liang X, Meng Y, Zhu Y, Li C, Zhou X, Hu S, Yi N, Lin Q, He S, Sun Y, Sheng J, Fan H, Li L, Peng L
Biomedicines 2024 Aug 19;12(8)
Biomedicines 2024 Aug 19;12(8)
Cytarabine prevents neuronal damage by enhancing AMPK to stimulate PINK1 / Parkin-involved mitophagy in Parkinson's disease model.
Li L, Zhang Y, Chen Z, Xu C, Xu Z, Pei H, Wang W, Yao R, Hao C
European journal of pharmacology 2024 Aug 15;977:176743
European journal of pharmacology 2024 Aug 15;977:176743
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Wang L, Wang B, Zhang X, Yang Z, Zhang X, Gong H, Song Y, Zhang K, Sun M
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Sex differences in the neuronal transcriptome and synaptic mitochondrial function in the cerebral cortex of a multiple sclerosis model.
Itoh N, Itoh Y, Stiles L, Voskuhl R
Frontiers in neurology 2023;14:1268411
Frontiers in neurology 2023;14:1268411
Reduced ER-mitochondrial contact sites and mitochondrial Ca(2+) flux in PRKN-mutant patient tyrosine hydroxylase reporter iPSC lines.
Yokota M, Yoshino Y, Hosoi M, Hashimoto R, Kakuta S, Shiga T, Ishikawa KI, Okano H, Hattori N, Akamatsu W, Koike M
Frontiers in cell and developmental biology 2023;11:1171440
Frontiers in cell and developmental biology 2023;11:1171440
PCSK9 Promotes Hypoxia-Induced EC Pyroptosis by Regulating Smac Mitochondrion-Cytoplasm Translocation in Critical Limb Ischemia.
Zhang M, Chen Y, Qiu Y, Sun J, He J, Liu Z, Shi J, Wei W, Wu G, Liang J
JACC. Basic to translational science 2023 Sep;8(9):1060-1077
JACC. Basic to translational science 2023 Sep;8(9):1060-1077
Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer.
Sun X, Ye G, Li J, Shou H, Bai G, Zhang J
Clinical and translational medicine 2023 Oct;13(10):e1457
Clinical and translational medicine 2023 Oct;13(10):e1457
Heterogeneity of perivascular astrocyte endfeet depending on vascular regions in the mouse brain.
Kameyama T, Miyata M, Shiotani H, Adachi J, Kakuta S, Uchiyama Y, Mizutani K, Takai Y
iScience 2023 Oct 20;26(10):108010
iScience 2023 Oct 20;26(10):108010
Longitudinal diffusion barriers imposed by myofilaments and mitochondria in murine cardiac myocytes.
Deisl C, Chung JH, Hilgemann DW
The Journal of general physiology 2023 Oct 2;155(10)
The Journal of general physiology 2023 Oct 2;155(10)
ER-associated degradation in cystinosis pathogenesis and the prospects of precision medicine.
Venkatarangan V, Zhang W, Yang X, Thoene J, Hahn SH, Li M
The Journal of clinical investigation 2023 Oct 2;133(19)
The Journal of clinical investigation 2023 Oct 2;133(19)
The poxvirus F17 protein counteracts mitochondrially orchestrated antiviral responses.
Meade N, Toreev HK, Chakrabarty RP, Hesser CR, Park C, Chandel NS, Walsh D
Nature communications 2023 Nov 30;14(1):7889
Nature communications 2023 Nov 30;14(1):7889
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
Chen L, Mao M, Liu D, Liu W, Wang Y, Xie L, Deng Y, Lin Y, Xu Y, Zhong X, Cao W
International immunopharmacology 2023 Mar;116:109648
International immunopharmacology 2023 Mar;116:109648
Mitochondrial Methionyl-tRNA Formyltransferase Deficiency Alleviates Metaflammation by Modulating Mitochondrial Activity in Mice.
Sun X, Liu S, Cai J, Yang M, Li C, Tan M, He B
International journal of molecular sciences 2023 Mar 22;24(6)
International journal of molecular sciences 2023 Mar 22;24(6)
Inhibiting NLRP3 Inflammasome Activation by CY-09 Helps to Restore Cerebral Glucose Metabolism in 3×Tg-AD Mice.
Han S, He Z, Hu X, Li X, Zheng K, Huang Y, Xiao P, Xie Q, Ni J, Liu Q
Antioxidants (Basel, Switzerland) 2023 Mar 15;12(3)
Antioxidants (Basel, Switzerland) 2023 Mar 15;12(3)
Exercise protects aged mice against coronary endothelial senescence via FUNDC1-dependent mitophagy.
Ma L, Li K, Wei W, Zhou J, Li Z, Zhang T, Wangsun Y, Tian F, Dong Q, Zhang H, Xing W
Redox biology 2023 Jun;62:102693
Redox biology 2023 Jun;62:102693
Artesunate protects against ocular fibrosis by suppressing fibroblast activation and inducing mitochondria-dependent ferroptosis.
Liu J, Pan Z, Tong B, Wang C, Yang J, Zou J, Jiang J, Zhang L, Jiang B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jun;37(6):e22954
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jun;37(6):e22954
Sodium houttuyfonate exerts its neuroprotection effect by inhibiting the M1 microglia polarization in a TLR4/NF-κB signal pathway.
Tang W, Liu L, Yan Y, Xia Y
Brain research 2023 Jun 15;1809:148358
Brain research 2023 Jun 15;1809:148358
SCP2 mediates the transport of lipid hydroperoxides to mitochondria in chondrocyte ferroptosis.
Dai T, Xue X, Huang J, Yang Z, Xu P, Wang M, Xu W, Feng Z, Zhu W, Xu Y, Chen J, Li S, Meng Q
Cell death discovery 2023 Jul 8;9(1):234
Cell death discovery 2023 Jul 8;9(1):234
Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal.
Yeh DW, Liu C, Hernandez JC, Tahara SM, Tsukamoto H, Machida K
iScience 2023 Jul 21;26(7):107035
iScience 2023 Jul 21;26(7):107035
QKI shuttles internal m(7)G-modified transcripts into stress granules and modulates mRNA metabolism.
Zhao Z, Qing Y, Dong L, Han L, Wu D, Li Y, Li W, Xue J, Zhou K, Sun M, Tan B, Chen Z, Shen C, Gao L, Small A, Wang K, Leung K, Zhang Z, Qin X, Deng X, Xia Q, Su R, Chen J
Cell 2023 Jul 20;186(15):3208-3226.e27
Cell 2023 Jul 20;186(15):3208-3226.e27
Oligomeric CHMP7 mediates three-way ER junctions and ER-mitochondria interactions.
Chu Q, Wang J, Du Y, Zhou T, Shi A, Xiong J, Ji WK, Deng L
Cell death and differentiation 2023 Jan;30(1):94-110
Cell death and differentiation 2023 Jan;30(1):94-110
Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax.
Li J, Sun X, Yang N, Ni J, Xie H, Guo H, Wang X, Zhou L, Liu J, Chen S, Wang X, Zhang Y, Yu C, Zhang W, Lu L
Kidney international 2023 Jan;103(1):115-133
Kidney international 2023 Jan;103(1):115-133
Effects of dapagliflozin monotherapy and combined aerobic exercise on skeletal muscle mitochondrial quality control and insulin resistance in type 2 diabetes mellitus rats.
Zhang L, Lin H, Yang X, Shi J, Sheng X, Wang L, Li T, Quan H, Zhai X, Li W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115852
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115852
High Sucrose Diet-Induced Subunit I Tyrosine 304 Phosphorylation of Cytochrome c Oxidase Leads to Liver Mitochondrial Respiratory Dysfunction in the Cohen Diabetic Rat Model.
Arroum T, Pham L, Raisanen TE, Morse PT, Wan J, Bell J, Lax R, Saada A, Hüttemann M, Weksler-Zangen S
Antioxidants (Basel, Switzerland) 2023 Dec 21;13(1)
Antioxidants (Basel, Switzerland) 2023 Dec 21;13(1)
Guf1 overexpression improves pancreatic β cell functions in type 2 diabetes mellitus rats with Roux-en-Y gastric bypass (RYGB) surgery.
Li P, Dai S, Gao X, Li W
Journal of physiology and biochemistry 2023 Aug;79(3):569-582
Journal of physiology and biochemistry 2023 Aug;79(3):569-582
The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy.
Gok MO, Connor OM, Wang X, Menezes CJ, Llamas CB, Mishra P, Friedman JR
The Journal of cell biology 2023 Apr 3;222(4)
The Journal of cell biology 2023 Apr 3;222(4)
CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth.
Yin S, Liu L, Ball LE, Wang Y, Bedford MT, Duncan SA, Wang H, Gan W
Cell reports 2023 Apr 25;42(4):112316
Cell reports 2023 Apr 25;42(4):112316
ATF5 regulates tubulointerstitial injury in diabetic kidney disease via mitochondrial unfolded protein response.
Liu Y, Zhang L, Zhang S, Liu J, Li X, Yang K, Yang D, Liu Y, Sun L, Liu F, Xiao L
Molecular medicine (Cambridge, Mass.) 2023 Apr 24;29(1):57
Molecular medicine (Cambridge, Mass.) 2023 Apr 24;29(1):57
MLN2238 exerts its anti-tumor effects via regulating ROS/JNK/mitochondrial signaling pathways in intrahepatic cholangiocarcinoma.
Xu H, Xu G, Xu Q, Xu C, Zhou X, Bai Y, Yin L, Ding Y, Wang W
Frontiers in pharmacology 2022;13:1040847
Frontiers in pharmacology 2022;13:1040847
Transient Receptor Potential Vanilloid Type 1 Protects Against Pressure Overload-Induced Cardiac Hypertrophy by Promoting Mitochondria-Associated Endoplasmic Reticulum Membranes.
Wang Y, Li X, Xu X, Qu X, Yang Y
Journal of cardiovascular pharmacology 2022 Sep 1;80(3):430-441
Journal of cardiovascular pharmacology 2022 Sep 1;80(3):430-441
Paternal cadmium exposure affects testosterone synthesis by reducing the testicular cholesterol pool in offspring mice.
Zhou J, Zhang Y, Zeng L, Wang X, Mu H, Wang M, Pan H, Su P
Ecotoxicology and environmental safety 2022 Sep 1;242:113947
Ecotoxicology and environmental safety 2022 Sep 1;242:113947
The Endoplasmic Reticulum ATP13A1 is Essential for MAVS-Mediated Antiviral Innate Immunity.
Zhang R, Hou X, Wang C, Li J, Zhu J, Jiang Y, Hou F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Nov;9(33):e2203831
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Nov;9(33):e2203831
Acyl-CoA thioesterase 9 promotes tumour growth and metastasis through reprogramming of fatty acid metabolism in hepatocellular carcinoma.
Wang B, Zhang H, Chen YF, Hu LQ, Tian YY, Tong HW, Wang G, Chen C, Yuan P
Liver international : official journal of the International Association for the Study of the Liver 2022 Nov;42(11):2548-2561
Liver international : official journal of the International Association for the Study of the Liver 2022 Nov;42(11):2548-2561
Cadmium-induced apoptosis of Leydig cells is mediated by excessive mitochondrial fission and inhibition of mitophagy.
Yi L, Shang XJ, Lv L, Wang Y, Zhang J, Quan C, Shi Y, Liu Y, Zhang L
Cell death & disease 2022 Nov 5;13(11):928
Cell death & disease 2022 Nov 5;13(11):928
Salidroside reduces neuropathology in Alzheimer's disease models by targeting NRF2/SIRT3 pathway.
Yao Y, Ren Z, Yang R, Mei Y, Dai Y, Cheng Q, Xu C, Xu X, Wang S, Kim KM, Noh JH, Zhu J, Zhao N, Liu YU, Mao G, Sima J
Cell & bioscience 2022 Nov 4;12(1):180
Cell & bioscience 2022 Nov 4;12(1):180
COX7A1 enhances the sensitivity of human NSCLC cells to cystine deprivation-induced ferroptosis via regulating mitochondrial metabolism.
Feng Y, Xu J, Shi M, Liu R, Zhao L, Chen X, Li M, Zhao Y, Chen J, Du W, Liu P
Cell death & disease 2022 Nov 23;13(11):988
Cell death & disease 2022 Nov 23;13(11):988
Triacetyl Resveratrol Inhibits PEDV by Inducing the Early Apoptosis In Vitro.
Wang X, Liu Y, Li K, Yang M, Wang Q, Hao Z
International journal of molecular sciences 2022 Nov 22;23(23)
International journal of molecular sciences 2022 Nov 22;23(23)
O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.
Cao Y, Zhang M, Li Y, Lu J, Zhou W, Li X, Shi H, Xu B, Li S
International journal of molecular sciences 2022 Nov 22;23(23)
International journal of molecular sciences 2022 Nov 22;23(23)
Repeated social defeat stress inhibits development of hippocampus neurons through mitophagy and autophagy.
Guo L, Jiang ZM, Sun RX, Pang W, Zhou X, Du ML, Chen MX, Lv X, Wang JT
Brain research bulletin 2022 May;182:111-117
Brain research bulletin 2022 May;182:111-117
PFKP alleviates glucose starvation-induced metabolic stress in lung cancer cells via AMPK-ACC2 dependent fatty acid oxidation.
Chen J, Zou L, Lu G, Grinchuk O, Fang L, Ong DST, Taneja R, Ong CN, Shen HM
Cell discovery 2022 May 31;8(1):52
Cell discovery 2022 May 31;8(1):52
Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults.
Singh A, D'Amico D, Andreux PA, Fouassier AM, Blanco-Bose W, Evans M, Aebischer P, Auwerx J, Rinsch C
Cell reports. Medicine 2022 May 17;3(5):100633
Cell reports. Medicine 2022 May 17;3(5):100633
A novel polyethylene glycol (PEG)-drug conjugate of Venetoclax, a Bcl-2 inhibitor, for treatment of acute myeloid leukemia (AML).
Ando H, Murakami Y, Eshima K, Ishida T
Cancer reports (Hoboken, N.J.) 2022 Mar;5(3):e1485
Cancer reports (Hoboken, N.J.) 2022 Mar;5(3):e1485
C19orf12 ablation causes ferroptosis in mitochondrial membrane protein-associated with neurodegeneration.
Shao C, Zhu J, Ma X, Siedlak SL, Cohen ML, Lerner A, Wang W
Free radical biology & medicine 2022 Mar;182:23-33
Free radical biology & medicine 2022 Mar;182:23-33
Inhibition of Fatty Acid Translocase (FAT/CD36) Palmitoylation Enhances Hepatic Fatty Acid β-Oxidation by Increasing Its Localization to Mitochondria and Interaction with Long-Chain Acyl-CoA Synthetase 1.
Zeng S, Wu F, Chen M, Li Y, You M, Zhang Y, Yang P, Wei L, Ruan XZ, Zhao L, Chen Y
Antioxidants & redox signaling 2022 Jun;36(16-18):1081-1100
Antioxidants & redox signaling 2022 Jun;36(16-18):1081-1100
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.
Han T, Wang P, Wang Y, Xun W, Lei J, Wang T, Lu Z, Gan M, Zhang W, Yu B, Wang JB
Autophagy 2022 Jun;18(6):1416-1432
Autophagy 2022 Jun;18(6):1416-1432
Ruthenium 360 and mitoxantrone inhibit mitochondrial calcium uniporter channel to prevent liver steatosis induced by high-fat diet.
Zhang Z, Luo Z, Yu L, Xiao Y, Liu S, ALuo Z, Ma Z, Huang L, Xiao L, Jia M, Song Z, Zhang H, Li Y, Zhou L
British journal of pharmacology 2022 Jun;179(11):2678-2696
British journal of pharmacology 2022 Jun;179(11):2678-2696
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Lu J, Fu S, Dai J, Hu J, Li S, Ji H, Wang Z, Yu J, Bao J, Xu B, Guo J, Yang H
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
Maternal Herpesviridae infection during pregnancy alters midbrain dopaminergic signatures in adult offspring.
Burmeister AR, Gordevicius J, Paul EN, Houck C, George S, Escobar Galvis ML, Sha Q, Brundin P, Pospisilik JA, Racicot K, Brundin L
Neurobiology of disease 2022 Jul;169:105720
Neurobiology of disease 2022 Jul;169:105720
Epigallocatechin-3-gallate exerts cardioprotective effects related to energy metabolism in pressure overload-induced cardiac dysfunction.
Mou Q, Jia Z, Luo M, Liu L, Huang X, Quan J, Tian J
Archives of biochemistry and biophysics 2022 Jul 15;723:109217
Archives of biochemistry and biophysics 2022 Jul 15;723:109217
Mitochondrial PKM2 deacetylation by procyanidin B2-induced SIRT3 upregulation alleviates lung ischemia/reperfusion injury.
Zhao J, Wang G, Han K, Wang Y, Wang L, Gao J, Zhao S, Wang G, Chen S, Luo A, Wu J, Wang G
Cell death & disease 2022 Jul 11;13(7):594
Cell death & disease 2022 Jul 11;13(7):594
Identification of a novel native peptide derived from 60S ribosomal protein L23a that translationally regulates p53 to reduce myocardial ischemia-reperfusion.
Yin A, Feng M, Zhang L, Cheng Z, Li Y, Qian L
Pharmacological research 2022 Jan;175:105988
Pharmacological research 2022 Jan;175:105988
Interfering with mitochondrial dynamics sensitizes glioblastoma multiforme to temozolomide chemotherapy.
Wang N, Huang R, Yang K, He Y, Gao Y, Dong D
Journal of cellular and molecular medicine 2022 Feb;26(3):893-912
Journal of cellular and molecular medicine 2022 Feb;26(3):893-912
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy.
Sun X, Shu Y, Ye G, Wu C, Xu M, Gao R, Huang D, Zhang J
Acta pharmaceutica Sinica. B 2022 Feb;12(2):838-852
Acta pharmaceutica Sinica. B 2022 Feb;12(2):838-852
Characterization of lncRNA functioning in ovine conceptuses and endometria during the peri-implantation period.
Matsuno Y, Kusama K, Imakawa K
Biochemical and biophysical research communications 2022 Feb 26;594:22-30
Biochemical and biophysical research communications 2022 Feb 26;594:22-30
PACS2-TRPV1 axis is required for ER-mitochondrial tethering during ER stress and lung fibrosis.
Knoell J, Chillappagari S, Knudsen L, Korfei M, Dartsch R, Jonigk D, Kuehnel MP, Hoetzenecker K, Guenther A, Mahavadi P
Cellular and molecular life sciences : CMLS 2022 Feb 25;79(3):151
Cellular and molecular life sciences : CMLS 2022 Feb 25;79(3):151
Myricetin Restores Aβ-Induced Mitochondrial Impairments in N2a-SW Cells.
Yao X, Zhang J, Lu Y, Deng Y, Zhao R, Xiao S
ACS chemical neuroscience 2022 Feb 16;13(4):454-463
ACS chemical neuroscience 2022 Feb 16;13(4):454-463
Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy.
Meng Y, Qiu L, Zeng X, Hu X, Zhang Y, Wan X, Mao X, Wu J, Xu Y, Xiong Q, Chen Z, Zhang B, Han J
Signal transduction and targeted therapy 2022 Dec 9;7(1):388
Signal transduction and targeted therapy 2022 Dec 9;7(1):388
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
Wang Y, Lei J, Zhang S, Wang X, Jin J, Liu Y, Gan M, Yuan Y, Sun L, Li X, Han T, Wang JB
Cell death & disease 2022 Dec 27;13(12):1075
Cell death & disease 2022 Dec 27;13(12):1075
The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP().
Liao Z, Gong Z, Wang Z, Yang W, Liu W, Hou L, Liu X, Hua J, Wang B, Li N
Cells 2022 Aug 30;11(17)
Cells 2022 Aug 30;11(17)
TRPML1-induced autophagy inhibition triggers mitochondrial mediated apoptosis.
Liu Y, Wang X, Zhu W, Sui Z, Wei X, Zhang Y, Qi J, Xing Y, Wang W
Cancer letters 2022 Aug 10;541:215752
Cancer letters 2022 Aug 10;541:215752
Downregulating MFN2 Promotes the Differentiation of Induced Pluripotent Stem Cells into Mesenchymal Stem Cells through the PI3K/Akt/GSK-3β/Wnt Signaling Pathway.
Deng L, Yi S, Yin X, Li Y, Luan Q
Stem cells and development 2022 Apr;31(7-8):181-194
Stem cells and development 2022 Apr;31(7-8):181-194
MFN2 knockdown promotes osteogenic differentiation of iPSC-MSCs through aerobic glycolysis mediated by the Wnt/β-catenin signaling pathway.
Deng L, Yi S, Yin X, Li Y, Luan Q
Stem cell research & therapy 2022 Apr 12;13(1):162
Stem cell research & therapy 2022 Apr 12;13(1):162
Differential Expression Profiles and Potential Intergenerational Functions of tRNA-Derived Small RNAs in Mice After Cadmium Exposure.
Zeng L, Zhou J, Zhang Y, Wang X, Wang M, Su P
Frontiers in cell and developmental biology 2021;9:791784
Frontiers in cell and developmental biology 2021;9:791784
Cardioprotective Role of SIRT5 in Response to Acute Ischemia Through a Novel Liver-Cardiac Crosstalk Mechanism.
Zhou B, Xiao M, Hu H, Pei X, Xue Y, Miao G, Wang J, Li W, Du Y, Zhang P, Wei T
Frontiers in cell and developmental biology 2021;9:687559
Frontiers in cell and developmental biology 2021;9:687559
CRMP2 Is Involved in Regulation of Mitochondrial Morphology and Motility in Neurons.
Brustovetsky T, Khanna R, Brustovetsky N
Cells 2021 Oct 17;10(10)
Cells 2021 Oct 17;10(10)
NAD(+) Repletion Reverses Heart Failure With Preserved Ejection Fraction.
Tong D, Schiattarella GG, Jiang N, Altamirano F, Szweda PA, Elnwasany A, Lee DI, Yoo H, Kass DA, Szweda LI, Lavandero S, Verdin E, Gillette TG, Hill JA
Circulation research 2021 May 28;128(11):1629-1641
Circulation research 2021 May 28;128(11):1629-1641
8a, a New Acridine Antiproliferative and Pro-Apoptotic Agent Targeting HDAC1/DNMT1.
Zhang Q, Wang Z, Chen X, Qiu H, Gu Y, Wang N, Wang T, Wang Z, Ma H, Zhao Y, Zhang B
International journal of molecular sciences 2021 May 24;22(11)
International journal of molecular sciences 2021 May 24;22(11)
High Dietary Fat Consumption Impairs Axonal Mitochondrial Function In Vivo.
Sajic M, Rumora AE, Kanhai AA, Dentoni G, Varatharajah S, Casey C, Brown RDR, Peters F, Hinder LM, Savelieff MG, Feldman EL, Smith KJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 May 12;41(19):4321-4334
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 May 12;41(19):4321-4334
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
Shi M, Huang XY, Ren XY, Wei XY, Ma Y, Lin ZZ, Liu DT, Song L, Zhao TJ, Li G, Yao L, Zhu M, Zhang C, Xie C, Wu Y, Wu HM, Fan LP, Ou J, Zhan YH, Lin SY, Lin SC
Nature cell biology 2021 Mar;23(3):268-277
Nature cell biology 2021 Mar;23(3):268-277
SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis.
Shangguan X, He J, Ma Z, Zhang W, Ji Y, Shen K, Yue Z, Li W, Xin Z, Zheng Q, Cao Y, Pan J, Dong B, Cheng J, Wang Q, Xue W
Nature communications 2021 Mar 22;12(1):1812
Nature communications 2021 Mar 22;12(1):1812
Walnut-Derived Peptide Activates PINK1 via the NRF2/KEAP1/HO-1 Pathway, Promotes Mitophagy, and Alleviates Learning and Memory Impairments in a Mice Model.
Zhao F, Liu C, Fang L, Lu H, Wang J, Gao Y, Gabbianelli R, Min W
Journal of agricultural and food chemistry 2021 Mar 10;69(9):2758-2772
Journal of agricultural and food chemistry 2021 Mar 10;69(9):2758-2772
Novel NDUFA12 variants are associated with isolated complex I defect and variable clinical manifestation.
Torraco A, Nasca A, Verrigni D, Pennisi A, Zaki MS, Olivieri G, Assouline Z, Martinelli D, Maroofian R, Rizza T, Di Nottia M, Invernizzi F, Lamantea E, Longo D, Houlden H, Prokisch H, Rötig A, Dionisi-Vici C, Bertini E, Ghezzi D, Carrozzo R, Diodato D
Human mutation 2021 Jun;42(6):699-710
Human mutation 2021 Jun;42(6):699-710
Sulforaphane Balances Ca(2+) Homeostasis Injured by Excessive Fat via Mitochondria-Associated Membrane (MAM).
Tian S, Lei P, Zhang J, Sun Y, Li B, Shan Y
Molecular nutrition & food research 2021 Jul;65(14):e2001076
Molecular nutrition & food research 2021 Jul;65(14):e2001076
Tubular Mas receptor mediates lipid-induced kidney injury.
Kong Y, Zhao X, Qiu M, Lin Y, Feng P, Li S, Liang B, Zhu Q, Huang H, Li C, Wang W
Cell death & disease 2021 Jan 21;12(1):110
Cell death & disease 2021 Jan 21;12(1):110
Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line.
Yang W, Liu J, Hou L, Chen Q, Liu Y
Life sciences 2021 Jan 15;265:118796
Life sciences 2021 Jan 15;265:118796
Novel selective hexokinase 2 inhibitor Benitrobenrazide blocks cancer cells growth by targeting glycolysis.
Zheng M, Wu C, Yang K, Yang Y, Liu Y, Gao S, Wang Q, Li C, Chen L, Li H
Pharmacological research 2021 Feb;164:105367
Pharmacological research 2021 Feb;164:105367
The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
Khodayari N, Wang RL, Oshins R, Lu Y, Millett M, Aranyos AM, Mostofizadeh S, Scindia Y, Flagg TO, Brantly M
International journal of molecular sciences 2021 Dec 9;22(24)
International journal of molecular sciences 2021 Dec 9;22(24)
Gelsolin Governs the Neuroendocrine Transdifferentiation of Prostate Cancer Cells and Suppresses the Apoptotic Machinery.
Oelrich F, Junker H, Stope MB, Erb HHH, Walther R, Venz S, Zimmermann U
Anticancer research 2021 Aug;41(8):3717-3729
Anticancer research 2021 Aug;41(8):3717-3729
DDAH2 suppresses RLR-MAVS-mediated innate antiviral immunity by stimulating nitric oxide-activated, Drp1-induced mitochondrial fission.
Huang S, Li Z, Wu Z, Liu C, Yu M, Wen M, Zhang L, Wang X
Science signaling 2021 Apr 13;14(678)
Science signaling 2021 Apr 13;14(678)
Citicoline Protects Auditory Hair Cells Against Neomycin-Induced Damage.
Zhong Z, Fu X, Li H, Chen J, Wang M, Gao S, Zhang L, Cheng C, Zhang Y, Li P, Zhang S, Qian X, Shu Y, Chai R, Gao X
Frontiers in cell and developmental biology 2020;8:712
Frontiers in cell and developmental biology 2020;8:712
Maternally Inherited Diabetes Mellitus Associated with a Novel m.15897G>A Mutation in Mitochondrial tRNA(Thr) Gene.
Li K, Wu L, Liu J, Lin W, Qi Q, Zhao T
Journal of diabetes research 2020;2020:2057187
Journal of diabetes research 2020;2020:2057187
Complex I mutations synergize to worsen the phenotypic expression of Leber's hereditary optic neuropathy.
Ji Y, Zhang J, Lu Y, Yi Q, Chen M, Xie S, Mao X, Xiao Y, Meng F, Zhang M, Yang R, Guan MX
The Journal of biological chemistry 2020 Sep 18;295(38):13224-13238
The Journal of biological chemistry 2020 Sep 18;295(38):13224-13238
miR-103a-3p regulates mitophagy in Parkinson's disease through Parkin/Ambra1 signaling.
Zhou J, Zhao Y, Li Z, Zhu M, Wang Z, Li Y, Xu T, Feng D, Zhang S, Tang F, Yao J
Pharmacological research 2020 Oct;160:105197
Pharmacological research 2020 Oct;160:105197
Mutant huntingtin does not cross the mitochondrial outer membrane.
Hamilton J, Brustovetsky T, Khanna R, Brustovetsky N
Human molecular genetics 2020 Oct 10;29(17):2962-2975
Human molecular genetics 2020 Oct 10;29(17):2962-2975
PDK4 promotes vascular calcification by interfering with autophagic activity and metabolic reprogramming.
Ma WQ, Sun XJ, Zhu Y, Liu NF
Cell death & disease 2020 Nov 17;11(11):991
Cell death & disease 2020 Nov 17;11(11):991
Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis.
Wang N, Liu H, Liu G, Li M, He X, Yin C, Tu Q, Shen X, Bai W, Wang Q, Tao Y, Yin H
Redox biology 2020 May;32:101495
Redox biology 2020 May;32:101495
Icariin protects human nucleus pulposus cells from hydrogen peroxide-induced mitochondria-mediated apoptosis by activating nuclear factor erythroid 2-related factor 2.
Hua W, Li S, Luo R, Wu X, Zhang Y, Liao Z, Song Y, Wang K, Zhao K, Yang S, Yang C
Biochimica et biophysica acta. Molecular basis of disease 2020 Jan 1;1866(1):165575
Biochimica et biophysica acta. Molecular basis of disease 2020 Jan 1;1866(1):165575
Activation of CaMKII via ER-stress mediates coxsackievirus B3-induced cardiomyocyte apoptosis.
Nie J, Ta N, Liu L, Shi G, Kang T, Zheng Z
Cell biology international 2020 Feb;44(2):488-498
Cell biology international 2020 Feb;44(2):488-498
NIPA2 regulates osteoblast function by modulating mitophagy in type 2 diabetes osteoporosis.
Zhao W, Zhang W, Ma H, Yang M
Scientific reports 2020 Feb 20;10(1):3078
Scientific reports 2020 Feb 20;10(1):3078
Estrogen receptors participate in silibinin-caused nuclear translocation of apoptosis-inducing factor in human breast cancer MCF-7 cells.
Liu W, Ji Y, Sun Y, Si L, Fu J, Hayashi T, Onodera S, Ikejima T
Archives of biochemistry and biophysics 2020 Aug 15;689:108458
Archives of biochemistry and biophysics 2020 Aug 15;689:108458
p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.
Zhao Y, Wang Z, Feng D, Zhao H, Lin M, Hu Y, Zhang N, Lv L, Gao Z, Zhai X, Tian X, Yao J
Theranostics 2019;9(5):1510-1522
Theranostics 2019;9(5):1510-1522
Spermidine Prevents Heart Injury in Neonatal Rats Exposed to Intrauterine Hypoxia by Inhibiting Oxidative Stress and Mitochondrial Fragmentation.
Chai N, Zhang H, Li L, Yu X, Liu Y, Lin Y, Wang L, Yan J, Nikolaevna SE, Zhao Y
Oxidative medicine and cellular longevity 2019;2019:5406468
Oxidative medicine and cellular longevity 2019;2019:5406468
Corilagin Alleviates Nonalcoholic Fatty Liver Disease in High-Fat Diet-Induced C57BL/6 Mice by Ameliorating Oxidative Stress and Restoring Autophagic Flux.
Zhang R, Chu K, Zhao N, Wu J, Ma L, Zhu C, Chen X, Wei G, Liao M
Frontiers in pharmacology 2019;10:1693
Frontiers in pharmacology 2019;10:1693
Decreased expression of apoptosis-inducing factor in renal cell carcinoma is associated with poor prognosis and reduced postoperative survival.
Wang Z, Yuan C, Huang Y, Liu Z, Yu X, Lv C, Su Z
Oncology letters 2019 Sep;18(3):2805-2812
Oncology letters 2019 Sep;18(3):2805-2812
Mapping Interactome Networks of DNAJC11, a Novel Mitochondrial Protein Causing Neuromuscular Pathology in Mice.
Violitzi F, Perivolidi VI, Thireou T, Grivas I, Haralambous S, Samiotaki M, Panayotou G, Douni E
Journal of proteome research 2019 Nov 1;18(11):3896-3912
Journal of proteome research 2019 Nov 1;18(11):3896-3912
A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer.
Wang Y, Han T, Gan M, Guo M, Xie C, Jin J, Zhang S, Wang P, Cao J, Wang JB
Cell cycle (Georgetown, Tex.) 2019 May;18(9):1019-1032
Cell cycle (Georgetown, Tex.) 2019 May;18(9):1019-1032
The Otubain YOD1 Suppresses Aggregation and Activation of the Signaling Adaptor MAVS through Lys63-Linked Deubiquitination.
Liu C, Huang S, Wang X, Wen M, Zheng J, Wang W, Fu Y, Tian S, Li L, Li Z, Wang X
Journal of immunology (Baltimore, Md. : 1950) 2019 May 15;202(10):2957-2970
Journal of immunology (Baltimore, Md. : 1950) 2019 May 15;202(10):2957-2970
Contribution of mitochondrial ND1 3394T>C mutation to the phenotypic manifestation of Leber's hereditary optic neuropathy.
Ji Y, Zhang J, Yu J, Wang Y, Lu Y, Liang M, Li Q, Jin X, Wei Y, Meng F, Gao Y, Cang X, Tong Y, Liu X, Zhang M, Jiang P, Zhu T, Mo JQ, Huang T, Jiang P, Guan MX
Human molecular genetics 2019 May 1;28(9):1515-1529
Human molecular genetics 2019 May 1;28(9):1515-1529
Deletion of Gtpbp3 in zebrafish revealed the hypertrophic cardiomyopathy manifested by aberrant mitochondrial tRNA metabolism.
Chen D, Zhang Z, Chen C, Yao S, Yang Q, Li F, He X, Ai C, Wang M, Guan MX
Nucleic acids research 2019 Jun 4;47(10):5341-5355
Nucleic acids research 2019 Jun 4;47(10):5341-5355
A Multidimensional Characterization of E3 Ubiquitin Ligase and Substrate Interaction Network.
Chen D, Liu X, Xia T, Tekcham DS, Wang W, Chen H, Li T, Lu C, Ning Z, Liu X, Liu J, Qi H, He H, Piao HL
iScience 2019 Jun 28;16:177-191
iScience 2019 Jun 28;16:177-191
JNK activation-mediated nuclear SIRT1 protein suppression contributes to silica nanoparticle-induced pulmonary damage via p53 acetylation and cytoplasmic localisation.
Zhao X, Wu Y, Li J, Li D, Jin Y, Zhu P, Liu Y, Zhuang Y, Yu S, Cao W, Wei H, Wang X, Han Y, Chen G
Toxicology 2019 Jul 1;423:42-53
Toxicology 2019 Jul 1;423:42-53
Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.
Li B, Cao Y, Meng G, Qian L, Xu T, Yan C, Luo O, Wang S, Wei J, Ding Y, Yu D
EBioMedicine 2019 Jan;39:239-254
EBioMedicine 2019 Jan;39:239-254
Autophagy Attenuation Hampers Progesterone Synthesis during the Development of Pregnant Corpus Luteum.
Tang Z, Zhang Z, Zhang H, Wang Y, Zhang Y, Zhao J, Yang H, Wang Z
Cells 2019 Dec 27;9(1)
Cells 2019 Dec 27;9(1)
Contribution of a mitochondrial tyrosyl-tRNA synthetase mutation to the phenotypic expression of the deafness-associated tRNA(Ser(UCN)) 7511A>G mutation.
Fan W, Zheng J, Kong W, Cui L, Aishanjiang M, Yi Q, Wang M, Cang X, Tang X, Chen Y, Mo JQ, Sondheimer N, Ge W, Guan MX
The Journal of biological chemistry 2019 Dec 13;294(50):19292-19305
The Journal of biological chemistry 2019 Dec 13;294(50):19292-19305
A novel iron(II) phenanthroline complex exhibits anticancer activity against TFR1-overexpressing esophageal squamous cell carcinoma cells through ROS accumulation and DNA damage.
Ye J, Ma J, Liu C, Huang J, Wang L, Zhong X
Biochemical pharmacology 2019 Aug;166:93-107
Biochemical pharmacology 2019 Aug;166:93-107
Mitochondrial NOS1 suppresses apoptosis in colon cancer cells through increasing SIRT3 activity.
Wang Q, Ye S, Chen X, Xu P, Li K, Zeng S, Huang M, Gao W, Chen J, Zhang Q, Zhong Z, Liu Q
Biochemical and biophysical research communications 2019 Aug 6;515(4):517-523
Biochemical and biophysical research communications 2019 Aug 6;515(4):517-523
Silibinin-induced apoptosis of breast cancer cells involves mitochondrial impairment.
Si L, Liu W, Hayashi T, Ji Y, Fu J, Nie Y, Mizuno K, Hattori S, Onodera S, Ikejima T
Archives of biochemistry and biophysics 2019 Aug 15;671:42-51
Archives of biochemistry and biophysics 2019 Aug 15;671:42-51
Mitochondrial dynamics and preconditioning in white matter.
Bastian C, Politano S, Day J, McCray A, Brunet S, Baltan S
Conditioning medicine 2018;1(2):64-72
Conditioning medicine 2018;1(2):64-72
Distinctive Structural and Molecular Features of Myelinated Inhibitory Axons in Human Neocortex.
Micheva KD, Chang EF, Nana AL, Seeley WW, Ting JT, Cobbs C, Lein E, Smith SJ, Weinberg RJ, Madison DV
eNeuro 2018 Sep-Oct;5(5)
eNeuro 2018 Sep-Oct;5(5)
Protective effects of mitochondrion-targeted peptide SS-31 against hind limb ischemia-reperfusion injury.
Cai J, Jiang Y, Zhang M, Zhao H, Li H, Li K, Zhang X, Qiao T
Journal of physiology and biochemistry 2018 May;74(2):335-343
Journal of physiology and biochemistry 2018 May;74(2):335-343
Picroside II Exerts a Neuroprotective Effect by Inhibiting mPTP Permeability and EndoG Release after Cerebral Ischemia/Reperfusion Injury in Rats.
Li S, Wang T, Zhai L, Ge K, Zhao J, Cong W, Guo Y
Journal of molecular neuroscience : MN 2018 Jan;64(1):144-155
Journal of molecular neuroscience : MN 2018 Jan;64(1):144-155
Metabolic and chemical regulation of tRNA modification associated with taurine deficiency and human disease.
Asano K, Suzuki T, Saito A, Wei FY, Ikeuchi Y, Numata T, Tanaka R, Yamane Y, Yamamoto T, Goto T, Kishita Y, Murayama K, Ohtake A, Okazaki Y, Tomizawa K, Sakaguchi Y, Suzuki T
Nucleic acids research 2018 Feb 28;46(4):1565-1583
Nucleic acids research 2018 Feb 28;46(4):1565-1583
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Zheng P, Chen Q, Tian X, Qian N, Chai P, Liu B, Hu J, Blackstone C, Zhu D, Teng J, Chen J
Cell research 2018 Aug;28(8):833-854
Cell research 2018 Aug;28(8):833-854
Exogenous H(2)S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice.
Sun Y, Tian Z, Liu N, Zhang L, Gao Z, Sun X, Yu M, Wu J, Yang F, Zhao Y, Ren H, Chen H, Zhao D, Wang Y, Dong S, Xu C, Lu F, Zhang W
Journal of molecular medicine (Berlin, Germany) 2018 Apr;96(3-4):281-299
Journal of molecular medicine (Berlin, Germany) 2018 Apr;96(3-4):281-299
Leukoencephalopathy due to Complex II Deficiency and Bi-Allelic SDHB Mutations: Further Cases and Implications for Genetic Counselling.
Grønborg S, Darin N, Miranda MJ, Damgaard B, Cayuela JA, Oldfors A, Kollberg G, Hansen TVO, Ravn K, Wibrand F, Østergaard E
JIMD reports 2017;33:69-77
JIMD reports 2017;33:69-77
Esculetin exerts antitumor effect on human gastric cancer cells through IGF-1/PI3K/Akt signaling pathway.
Wang G, Lu M, Yao Y, Wang J, Li J
European journal of pharmacology 2017 Nov 5;814:207-215
European journal of pharmacology 2017 Nov 5;814:207-215
Esculetin induces apoptosis of SMMC-7721 cells through IGF-1/PI3K/Akt-mediated mitochondrial pathways.
Li J, Li S, Wang X, Wang H
Canadian journal of physiology and pharmacology 2017 Jul;95(7):787-794
Canadian journal of physiology and pharmacology 2017 Jul;95(7):787-794
DJ-1 modulates mitochondrial response to oxidative stress: clues from a novel diagnosis of PARK7.
Di Nottia M, Masciullo M, Verrigni D, Petrillo S, Modoni A, Rizzo V, Di Giuda D, Rizza T, Niceta M, Torraco A, Bianchi M, Santoro M, Bentivoglio AR, Bertini E, Piemonte F, Carrozzo R, Silvestri G
Clinical genetics 2017 Jul;92(1):18-25
Clinical genetics 2017 Jul;92(1):18-25
Quinocetone induces mitochondrial apoptosis in HepG2 cells through ROS-dependent promotion of VDAC1 oligomerization and suppression of Wnt1/β-catenin signaling pathway.
Yang X, Tang S, Dai C, Li D, Zhang S, Deng S, Zhou Y, Xiao X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Jul;105:161-176
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Jul;105:161-176
Methyl jasmonate leads to necrosis and apoptosis in hepatocellular carcinoma cells via inhibition of glycolysis and represses tumor growth in mice.
Li J, Chen K, Wang F, Dai W, Li S, Feng J, Wu L, Liu T, Xu S, Xia Y, Lu J, Zhou Y, Xu L, Guo C
Oncotarget 2017 Jul 11;8(28):45965-45980
Oncotarget 2017 Jul 11;8(28):45965-45980
Upregulation of Spinal Voltage-Dependent Anion Channel 1 Contributes to Bone Cancer Pain Hypersensitivity in Rats.
Kong X, Wei J, Wang D, Zhu X, Zhou Y, Wang S, Xu GY, Jiang GQ
Neuroscience bulletin 2017 Dec;33(6):711-721
Neuroscience bulletin 2017 Dec;33(6):711-721
A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.
Malty RH, Aoki H, Kumar A, Phanse S, Amin S, Zhang Q, Minic Z, Goebels F, Musso G, Wu Z, Abou-Tok H, Meyer M, Deineko V, Kassir S, Sidhu V, Jessulat M, Scott NE, Xiong X, Vlasblom J, Prasad B, Foster LJ, Alberio T, Garavaglia B, Yu H, Bader GD, Nakamura K, Parkinson J, Babu M
Cell systems 2017 Dec 27;5(6):564-577.e12
Cell systems 2017 Dec 27;5(6):564-577.e12
Inhibition of p66Shc-mediated mitochondrial apoptosis via targeting prolyl-isomerase Pin1 attenuates intestinal ischemia/reperfusion injury in rats.
Feng D, Yao J, Wang G, Li Z, Zu G, Li Y, Luo F, Ning S, Qasim W, Chen Z, Tian X
Clinical science (London, England : 1979) 2017 Apr 25;131(8):759-773
Clinical science (London, England : 1979) 2017 Apr 25;131(8):759-773
Exercise Intolerance and Myoglobinuria Associated with a Novel Maternally Inherited MT-ND1 Mutation.
Rafiq J, Duno M, Østergaard E, Ravn K, Vissing CR, Wibrand F, Vissing J
JIMD reports 2016;25:65-70
JIMD reports 2016;25:65-70
Induction of Apoptosis by the Nonstructural Protein 4 and 10 of Porcine Reproductive and Respiratory Syndrome Virus.
Yuan S, Zhang N, Xu L, Zhou L, Ge X, Guo X, Yang H
PloS one 2016;11(6):e0156518
PloS one 2016;11(6):e0156518
Non-cytotoxic concentrations of acetaminophen induced mitochondrial biogenesis and antioxidant response in HepG2 cells.
Zhang T, Zhang Q, Guo J, Yuan H, Peng H, Cui L, Yin J, Zhang L, Zhao J, Li J, White A, Carmichael PL, Westmoreland C, Peng S
Environmental toxicology and pharmacology 2016 Sep;46:71-79
Environmental toxicology and pharmacology 2016 Sep;46:71-79
Synergistic inhibition of sunitinib and ethaselen against human colorectal cancer cells proliferation.
Zheng X, Zhang Y, Zhang L, Xu W, Ma W, Sun R, Zeng H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Oct;83:212-220
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Oct;83:212-220
Altered redox mitochondrial biology in the neurodegenerative disorder fragile X-tremor/ataxia syndrome: use of antioxidants in precision medicine.
Song G, Napoli E, Wong S, Hagerman R, Liu S, Tassone F, Giulivi C
Molecular medicine (Cambridge, Mass.) 2016 Oct;22:548-559
Molecular medicine (Cambridge, Mass.) 2016 Oct;22:548-559
Subcellular localization of DJ-1 in human HL-60 leukemia cells in response to diallyl disulfide treatment.
Li Q, Tang Y, Qin J, Yi L, Yang Y, Wang J, He J, Su Q, Tan H
Molecular medicine reports 2016 Nov;14(5):4666-4672
Molecular medicine reports 2016 Nov;14(5):4666-4672
Proteomics-based identification of VDAC1 as a tumor promoter in cervical carcinoma.
Zhang C, Ding W, Liu Y, Hu Z, Zhu D, Wang X, Yu L, Wang L, Shen H, Zhang W, Ren C, Li K, Weng D, Deng W, Ma D, Wang H
Oncotarget 2016 Aug 9;7(32):52317-52328
Oncotarget 2016 Aug 9;7(32):52317-52328
Phosphatase and tensin homologue (PTEN)-induced putative kinase 1 reduces pancreatic β-cells apoptosis in glucotoxicity through activation of autophagy.
Zhang J, Chen K, Wang L, Wan X, Shrestha C, Zhou J, Mo Z
Biochemical and biophysical research communications 2016 Aug 5;476(4):299-305
Biochemical and biophysical research communications 2016 Aug 5;476(4):299-305
Sepsis-induced brain mitochondrial dysfunction is associated with altered mitochondrial Src and PTP1B levels.
Lyu J, Zheng G, Chen Z, Wang B, Tao S, Xiang D, Xie M, Huang J, Liu C, Zeng Q
Brain research 2015 Sep 16;1620:130-8
Brain research 2015 Sep 16;1620:130-8
α-Enolase plays a catalytically independent role in doxorubicin-induced cardiomyocyte apoptosis and mitochondrial dysfunction.
Gao S, Li H, Feng XJ, Li M, Liu ZP, Cai Y, Lu J, Huang XY, Wang JJ, Li Q, Chen SR, Ye JT, Liu PQ
Journal of molecular and cellular cardiology 2015 Feb;79:92-103
Journal of molecular and cellular cardiology 2015 Feb;79:92-103
CLPB variants associated with autosomal-recessive mitochondrial disorder with cataract, neutropenia, epilepsy, and methylglutaconic aciduria.
Saunders C, Smith L, Wibrand F, Ravn K, Bross P, Thiffault I, Christensen M, Atherton A, Farrow E, Miller N, Kingsmore SF, Ostergaard E
American journal of human genetics 2015 Feb 5;96(2):258-65
American journal of human genetics 2015 Feb 5;96(2):258-65
O-Alkylated derivatives of quercetin induce apoptosis of MCF-7 cells via a caspase-independent mitochondrial pathway.
Liao H, Bao X, Zhu J, Qu J, Sun Y, Ma X, Wang E, Guo X, Kang Q, Zhen Y
Chemico-biological interactions 2015 Dec 5;242:91-8
Chemico-biological interactions 2015 Dec 5;242:91-8
The self-interaction of a nodavirus replicase is enhanced by mitochondrial membrane lipids.
Qiu Y, Wang Z, Liu Y, Han Y, Miao M, Qi N, Yang J, Xia H, Li X, Qin CF, Hu Y, Zhou X
PloS one 2014;9(2):e89628
PloS one 2014;9(2):e89628
The mitochondrial thioredoxin is required for liver development in zebrafish.
Zhang J, Cui X, Wang L, Liu F, Jiang T, Li C, Li D, Huang M, Liao S, Wang J, Chen J, Jia H, He J, Tang Z, Yin Z, Liu M
Current molecular medicine 2014;14(6):772-82
Current molecular medicine 2014;14(6):772-82
Blockade of PKCβ protects against remote organ injury induced by intestinal ischemia and reperfusion via a p66shc-mediated mitochondrial apoptotic pathway.
Wang G, Chen Z, Zhang F, Jing H, Xu W, Ning S, Li Z, Liu K, Yao J, Tian X
Apoptosis : an international journal on programmed cell death 2014 Sep;19(9):1342-53
Apoptosis : an international journal on programmed cell death 2014 Sep;19(9):1342-53
Novel distribution of calreticulin to cardiomyocyte mitochondria and its increase in a rat model of dilated cardiomyopathy.
Zhang M, Wei J, Li Y, Shan H, Yan R, Lin L, Zhang Q, Xue J
Biochemical and biophysical research communications 2014 Jun 20;449(1):62-8
Biochemical and biophysical research communications 2014 Jun 20;449(1):62-8
Mitochondrial binding of α-enolase stabilizes mitochondrial membrane: its role in doxorubicin-induced cardiomyocyte apoptosis.
Gao S, Li H, Cai Y, Ye JT, Liu ZP, Lu J, Huang XY, Feng XJ, Gao H, Chen SR, Li M, Liu PQ
Archives of biochemistry and biophysics 2014 Jan 15;542:46-55
Archives of biochemistry and biophysics 2014 Jan 15;542:46-55
Inhibition of VDAC1 prevents Ca²⁺-mediated oxidative stress and apoptosis induced by 5-aminolevulinic acid mediated sonodynamic therapy in THP-1 macrophages.
Chen H, Gao W, Yang Y, Guo S, Wang H, Wang W, Zhang S, Zhou Q, Xu H, Yao J, Tian Z, Li B, Cao W, Zhang Z, Tian Y
Apoptosis : an international journal on programmed cell death 2014 Dec;19(12):1712-26
Apoptosis : an international journal on programmed cell death 2014 Dec;19(12):1712-26
Proteomic study reveals a co-occurrence of gallic acid-induced apoptosis and glycolysis in B16F10 melanoma cells.
Liu C, Lin JJ, Yang ZY, Tsai CC, Hsu JL, Wu YJ
Journal of agricultural and food chemistry 2014 Dec 3;62(48):11672-80
Journal of agricultural and food chemistry 2014 Dec 3;62(48):11672-80
Membrane association of Wuhan nodavirus protein A is required for its ability to accumulate genomic RNA1 template.
Qiu Y, Wang Z, Liu Y, Qi N, Miao M, Si J, Xiang X, Cai D, Hu Y, Zhou X
Virology 2013 May 10;439(2):140-51
Virology 2013 May 10;439(2):140-51
Distinct mechanisms of axonal globule formation in mice expressing human wild type α-synuclein or dementia with Lewy bodies-linked P123H β-synuclein.
Sekigawa A, Fujita M, Sekiyama K, Takamatsu Y, Hatano T, Rockenstein E, La Spada AR, Masliah E, Hashimoto M
Molecular brain 2012 Sep 26;5:34
Molecular brain 2012 Sep 26;5:34
Proteomic profiling of the 11-dehydrosinulariolide-treated oral carcinoma cells Ca9-22: effects on the cell apoptosis through mitochondrial-related and ER stress pathway.
Liu CI, Wang RY, Lin JJ, Su JH, Chiu CC, Chen JC, Chen JY, Wu YJ
Journal of proteomics 2012 Oct 22;75(18):5578-89
Journal of proteomics 2012 Oct 22;75(18):5578-89
Mitochondrial nitric oxide synthase participates in septic shock myocardial depression by nitric oxide overproduction and mitochondrial permeability transition pore opening.
Xu C, Yi C, Wang H, Bruce IC, Xia Q
Shock (Augusta, Ga.) 2012 Jan;37(1):110-5
Shock (Augusta, Ga.) 2012 Jan;37(1):110-5
Proteomic investigation of anti-tumor activities exerted by sinularin against A2058 melanoma cells.
Su TR, Lin JJ, Chiu CC, Chen JY, Su JH, Cheng ZJ, Hwang WI, Huang HH, Wu YJ
Electrophoresis 2012 Apr;33(7):1139-52
Electrophoresis 2012 Apr;33(7):1139-52
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 10866-1-AP(VDAC1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The VDAC1/Porin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human VDAC1/Porin. This antibody recognizes human,mouse,rat antigen. The VDAC1/Porin antibody has been validated for the following applications: ELISA, WB, IHC, IP, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-VDAC1 (IP:10866-1-AP, 3ug; Detection:10866-1-AP 1:1000) with mouse skeletal muscle tissue lysate 7500ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 10866-1-AP(VDAC1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
