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- References [21]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 11039-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11039-1-AP, RRID:AB_2245927
- Product name
- Transketolase antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Transketolase antibody (Cat. #11039-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Metabolic reprogramming driven by EZH2 inhibition depends on cell-matrix interactions.
Transketolase drives the development of aortic dissection by impairing mitochondrial bioenergetics.
M6A-modified circRBM33 promotes prostate cancer progression via PDHA1-mediated mitochondrial respiration regulation and presents a potential target for ARSI therapy.
Depressed Proximal Glycolysis in Myocardium Of Human Heart Failure with Preserved Ejection Fraction.
The complexity of EGFR exon 19 deletion and L858R mutant cells as assessed by proteomics, transcriptomics, and metabolomics.
Erythritol synthesis is elevated in response to oxidative stress and regulated by the non-oxidative pentose phosphate pathway in A549 cells.
Inhibition of Transketolase Improves the Prognosis of Colorectal Cancer.
Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.
A cross-species spatiotemporal proteomic analysis identifies UBE3A-dependent signaling pathways and targets.
TRIM21 deficiency promotes cell proliferation and tumorigenesis via regulating p21 expression in ovarian cancer.
Glycolysis addiction compensating for a defective pentose phosphate pathway confers gemcitabine sensitivity in SETD2-deficient pancreatic cancer.
Integrative proteomics and metabolomics approach to elucidate metabolic dysfunction induced by silica nanoparticles in hepatocytes.
Transketolase promotes colorectal cancer metastasis through regulating AKT phosphorylation.
Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk.
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis.
Mitochondrial NADP(+) is essential for proline biosynthesis during cell growth.
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
Transketolase is upregulated in metastatic peritoneal implants and promotes ovarian cancer cell proliferation.
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.
Malignant pleural effusion cells show aberrant glucose metabolism gene expression.
Quantitative analysis of the secretome of TGF-beta signaling-deficient mammary fibroblasts.
W-M Fan T, Islam JMM, Higashi RM, Lin P, Brainson CF, Lane AN
The Journal of biological chemistry 2024 Jan;300(1):105485
The Journal of biological chemistry 2024 Jan;300(1):105485
Transketolase drives the development of aortic dissection by impairing mitochondrial bioenergetics.
Wang C, Zhang L, Zhang Q, Zheng H, Yang X, Cai W, Zou Q, Lin J, Zhang L, Zhong L, Li X, Liao Y, Liu Q, Chen L, Li Y
Acta physiologica (Oxford, England) 2024 Apr;240(4):e14113
Acta physiologica (Oxford, England) 2024 Apr;240(4):e14113
M6A-modified circRBM33 promotes prostate cancer progression via PDHA1-mediated mitochondrial respiration regulation and presents a potential target for ARSI therapy.
Zhong C, Long Z, Yang T, Wang S, Zhong W, Hu F, Teoh JY, Lu J, Mao X
International journal of biological sciences 2023;19(5):1543-1563
International journal of biological sciences 2023;19(5):1543-1563
Depressed Proximal Glycolysis in Myocardium Of Human Heart Failure with Preserved Ejection Fraction.
Koleini N, Meddeb M, Keykhaei M, Kwon S, Zhao L, Hahn V, Sharma K, Pearce EL, Kass DA
medRxiv : the preprint server for health sciences 2023 Oct 2;
medRxiv : the preprint server for health sciences 2023 Oct 2;
The complexity of EGFR exon 19 deletion and L858R mutant cells as assessed by proteomics, transcriptomics, and metabolomics.
Ochi N, Takeyama M, Miyake N, Fuchigami M, Yamane H, Fukazawa T, Nagasaki Y, Kawahara T, Nakanishi H, Takigawa N
Experimental cell research 2023 Mar 1;424(1):113503
Experimental cell research 2023 Mar 1;424(1):113503
Erythritol synthesis is elevated in response to oxidative stress and regulated by the non-oxidative pentose phosphate pathway in A549 cells.
Ortiz SR, Heinz A, Hiller K, Field MS
Frontiers in nutrition 2022;9:953056
Frontiers in nutrition 2022;9:953056
Inhibition of Transketolase Improves the Prognosis of Colorectal Cancer.
Zhang L, Huang Z, Cai Q, Zhao C, Xiao Y, Quan X, Tang C, Gao J
Frontiers in medicine 2022;9:837143
Frontiers in medicine 2022;9:837143
Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.
Yang R, Yang C, Ma L, Zhao Y, Guo Z, Niu J, Chu Q, Ma Y, Li B
Nature communications 2022 Nov 17;13(1):7031
Nature communications 2022 Nov 17;13(1):7031
A cross-species spatiotemporal proteomic analysis identifies UBE3A-dependent signaling pathways and targets.
Pandya NJ, Meier S, Tyanova S, Terrigno M, Wang C, Punt AM, Mientjes EJ, Vautheny A, Distel B, Kremer T, Elgersma Y, Jagasia R
Molecular psychiatry 2022 May;27(5):2590-2601
Molecular psychiatry 2022 May;27(5):2590-2601
TRIM21 deficiency promotes cell proliferation and tumorigenesis via regulating p21 expression in ovarian cancer.
Sun J, Chen X, Ji X, Meng S, Wang W, Wang P, Bai J, Li Z, Chen Y
Bioengineered 2022 Mar;13(3):6024-6035
Bioengineered 2022 Mar;13(3):6024-6035
Glycolysis addiction compensating for a defective pentose phosphate pathway confers gemcitabine sensitivity in SETD2-deficient pancreatic cancer.
Shen X, Chen Y, Liu M, Shi J, Tang Y, Yang X, Xu D, Yao H, Lu P, Sun Y, Xue J, Niu N
Biochemical and biophysical research communications 2022 Jul 30;615:9-16
Biochemical and biophysical research communications 2022 Jul 30;615:9-16
Integrative proteomics and metabolomics approach to elucidate metabolic dysfunction induced by silica nanoparticles in hepatocytes.
Zhu Y, Zhang Y, Li Y, Guo C, Fan Z, Li Y, Yang M, Zhou X, Sun Z, Wang J
Journal of hazardous materials 2022 Jul 15;434:128820
Journal of hazardous materials 2022 Jul 15;434:128820
Transketolase promotes colorectal cancer metastasis through regulating AKT phosphorylation.
Li M, Zhao X, Yong H, Xu J, Qu P, Qiao S, Hou P, Li Z, Chu S, Zheng J, Bai J
Cell death & disease 2022 Feb 2;13(2):99
Cell death & disease 2022 Feb 2;13(2):99
Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk.
Wang XH, Xu S, Zhou XY, Zhao R, Lin Y, Cao J, Zang WD, Tao H, Xu W, Li MQ, Zhao SM, Jin LP, Zhao JY
Nature communications 2021 Jun 8;12(1):3428
Nature communications 2021 Jun 8;12(1):3428
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis.
Chen X, Li Z, Yong H, Wang W, Wang D, Chu S, Li M, Hou P, Zheng J, Bai J
Cancer letters 2021 Jun 28;508:115-126
Cancer letters 2021 Jun 28;508:115-126
Mitochondrial NADP(+) is essential for proline biosynthesis during cell growth.
Tran DH, Kesavan R, Rion H, Soflaee MH, Solmonson A, Bezwada D, Vu HS, Cai F, Phillips JA 3rd, DeBerardinis RJ, Hoxhaj G
Nature metabolism 2021 Apr;3(4):571-585
Nature metabolism 2021 Apr;3(4):571-585
Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner.
Qin Z, Xiang C, Zhong F, Liu Y, Dong Q, Li K, Shi W, Ding C, Qin L, He F
Journal of experimental & clinical cancer research : CR 2019 Apr 11;38(1):154
Journal of experimental & clinical cancer research : CR 2019 Apr 11;38(1):154
Transketolase is upregulated in metastatic peritoneal implants and promotes ovarian cancer cell proliferation.
Ricciardelli C, Lokman NA, Cheruvu S, Tan IA, Ween MP, Pyragius CE, Ruszkiewicz A, Hoffmann P, Oehler MK
Clinical & experimental metastasis 2015 Jun;32(5):441-55
Clinical & experimental metastasis 2015 Jun;32(5):441-55
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.
Chen L, Shu Y, Liang X, Chen EC, Yee SW, Zur AA, Li S, Xu L, Keshari KR, Lin MJ, Chien HC, Zhang Y, Morrissey KM, Liu J, Ostrem J, Younger NS, Kurhanewicz J, Shokat KM, Ashrafi K, Giacomini KM
Proceedings of the National Academy of Sciences of the United States of America 2014 Jul 8;111(27):9983-8
Proceedings of the National Academy of Sciences of the United States of America 2014 Jul 8;111(27):9983-8
Malignant pleural effusion cells show aberrant glucose metabolism gene expression.
Lin CC, Chen LC, Tseng VS, Yan JJ, Lai WW, Su WP, Lin CH, Huang CY, Su WC
The European respiratory journal 2011 Jun;37(6):1453-65
The European respiratory journal 2011 Jun;37(6):1453-65
Quantitative analysis of the secretome of TGF-beta signaling-deficient mammary fibroblasts.
Xu BJ, Yan W, Jovanovic B, An AQ, Cheng N, Aakre ME, Yi Y, Eng J, Link AJ, Moses HL
Proteomics 2010 Jul;10(13):2458-70
Proteomics 2010 Jul;10(13):2458-70
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 11039-1-AP(TKT antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Transketolase antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Transketolase. This antibody recognizes human,mouse,rat antigen. The Transketolase antibody has been validated for the following applications: ELISA, WB, IHC analysis.
