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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [1]
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- Product number
- HPA029691 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA029691, RRID:AB_10600118
- Product name
- Anti-SIRT4
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human SIRT4, Gene description: sirtuin 4, Alternative Gene Names: SIR2L4, Validated applications: WB, IHC, Uniprot ID: Q9Y6E7, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references SIRT2 negatively regulates the cGASâSTING pathway by deacetylating G3BP1
SIRT4 functions as a tumor suppressor during prostate cancer by inducing apoptosis and inhibiting glutamine metabolism
Acetylation promotes BCAT2 degradation to suppress BCAA catabolism and pancreatic cancer growth
Overexpression of SIRT4 inhibits the proliferation of gastric cancer cells through cell cycle arrest
SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion
Li Y, Bie J, Song C, Li Y, Zhang T, Li H, Zhao L, You F, Luo J
EMBO reports 2023;24(12)
EMBO reports 2023;24(12)
SIRT4 functions as a tumor suppressor during prostate cancer by inducing apoptosis and inhibiting glutamine metabolism
Cai G, Ge Z, Xu Y, Cai L, Sun P, Huang G
Scientific Reports 2022;12(1)
Scientific Reports 2022;12(1)
Acetylation promotes BCAT2 degradation to suppress BCAA catabolism and pancreatic cancer growth
Lei M, Li X, Zhang Y, Li J, Zhang F, Wang Y, Yin M, Qu J, Lei Q
Signal Transduction and Targeted Therapy 2020;5(1)
Signal Transduction and Targeted Therapy 2020;5(1)
SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism
Chen Z, Lin J, Feng S, Chen X, Huang H, Wang C, Yu Y, He Y, Han S, Zheng L, Huang G
OncoTargets and Therapy 2019;Volume 12
OncoTargets and Therapy 2019;Volume 12
Overexpression of SIRT4 inhibits the proliferation of gastric cancer cells through cell cycle arrest
Hu Y, Lin J, Lin Y, Chen X, Zhu G, Huang G
Oncology Letters 2018
Oncology Letters 2018
SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion
Anderson K, Huynh F, Fisher-Wellman K, Stuart J, Peterson B, Douros J, Wagner G, Thompson J, Madsen A, Green M, Sivley R, Ilkayeva O, Stevens R, Backos D, Capra J, Olsen C, Campbell J, Muoio D, Grimsrud P, Hirschey M
Cell Metabolism 2017;25(4):838-855.e15
Cell Metabolism 2017;25(4):838-855.e15
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Recombinant expression validation
- Main image
- Experimental details
- Western blot analysis in control (vector only transfected HEK293T lysate) and SIRT4 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY402175).
- Sample type
- Human
- Protocol
- Protocol
