Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- HPA029692 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA029692, RRID:AB_10611520
- Product name
- Anti-SIRT4
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human SIRT4, Gene description: sirtuin 4, Alternative Gene Names: SIR2L4, Validated applications: IHC, WB, Uniprot ID: Q9Y6E7, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references SIRT4 is an independent prognostic factor in bladder cancer and inhibits bladder cancer growth by suppressing autophagy
SIRT4 functions as a tumor suppressor during prostate cancer by inducing apoptosis and inhibiting glutamine metabolism
Sirtuin-4 (SIRT4) is downregulated and associated with some clinicopathological features in gastric adenocarcinoma
Yin J, Cai G, Wang H, Chen W, Liu S, Huang G
Cell Division 2023;18(1)
Cell Division 2023;18(1)
SIRT4 functions as a tumor suppressor during prostate cancer by inducing apoptosis and inhibiting glutamine metabolism
Cai G, Ge Z, Xu Y, Cai L, Sun P, Huang G
Scientific Reports 2022;12(1)
Scientific Reports 2022;12(1)
Sirtuin-4 (SIRT4) is downregulated and associated with some clinicopathological features in gastric adenocarcinoma
Huang G, Cui F, Yu F, Lu H, Zhang M, Tang H, Peng Z
Biomedicine & Pharmacotherapy 2015;72
Biomedicine & Pharmacotherapy 2015;72
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Recombinant expression validation
- Main image
- Experimental details
- Western blot analysis in control (vector only transfected HEK293T lysate) and SIRT4 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY402175).
- Sample type
- Human
- Protocol
- Protocol
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human testis and pancreas tissues using Anti-SIRT4 antibody. Corresponding SIRT4 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol