27463-1-AP

antibody from Proteintech Group

Targeting: TRIM8 GERP, RNF27

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

27463-1-AP

Provider

Proteintech Group

Product name

TRIM8 antibody

Antibody type

Polyclonal

Description

TRIM8 antibody (Cat. #27463-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

ITLN1 exacerbates Crohn's colitis by driving ZBP1-dependent PANoptosis in intestinal epithelial cells through antagonizing TRIM8-mediated CAPN2 ubiquitination.

Zhao J, Li Y, Ying P, Zhou Y, Xu Z, Wang D, Wang H, Tang L
International journal of biological sciences 2025;21(8):3705-3725

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TRIM8-dependent K63-ubiquitinated PGK1 promotes glycolysis and angiogenesis in gastric cancer via interaction with ACAT1.

Feng A, Zhang J, Wang Z, Chen Z, Fang K, Li Z, Jiang H, Leng Z, Zhang S, Chu Y, Lian J, Chen T, Ye L, Xu M, He L
Cell death & disease 2025 Nov 3;16(1):780

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SCAP Interacts with Trim27 to Promote Vascular Neointimal Hyperplasia by Regulating the Stability and Ubiquitination of IκBα.

Yao Y, Wang X, Xuan C, Li D, Huang W, Wei L, Ruan XZ, Li D, Chen Y
Aging and disease 2025 Aug 6;

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TRIM8 promotes ovarian cancer proliferation and migration by targeting VDAC2 for ubiquitination and degradation.

Wu F, Xu J, Jin X, Zhu Y, Gao W, Liu M, Zhang Y, Qian W, Huang X, Zhao D, Feng G, Hou S, Xi X
Cancer medicine 2024 Jun;13(11):e7396

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The prognostic value of ubiquitin/ubiquitin-like-related genes along with immune cell infiltration and clinicopathological features in osteosarcoma.

Wen J, Wan L, Chen W, Dong X
Journal of orthopaedic surgery and research 2024 Jun 15;19(1):356

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Inhibiting TRIM8 alleviates adipocyte inflammation and insulin resistance by regulating the DUSP14/MAPKs pathway.

Zhu M, Pu J, Zhang T, Shao H, Su R, Tang C
Adipocyte 2024 Dec;13(1):2381262

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Mutual regulation between TRIM21 and TRIM8 via K48-linked ubiquitination.

Wang L, Li H, Huang A, Zhao Y, Xiao C, Dong J, Liu X, Shao N
Oncogene 2023 Dec;42(50):3708-3718

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Five hypoxia and immunity related genes as potential biomarkers for the prognosis of osteosarcoma.

Liu D, Hu Z, Jiang J, Zhang J, Hu C, Huang J, Wei Q
Scientific reports 2022 Jan 31;12(1):1617

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Down-regulation of long noncoding RNA LINC00472 alleviates sepsis-induced acute hepatic injury by regulating miR-373-3p/TRIM8 axis.

Li L, He Y, He XJ, Bi MR, Qi YH, Zhu WW
Experimental and molecular pathology 2020 Dec;117:104562