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- Antibody Data
- Antigen structure
- References [1349]
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- Immunoprecipitation [1]
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- Product number
- 11224-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11224-1-AP, RRID:AB_2210206
- Product name
- alpha Tubulin antibody
- Antibody type
- Polyclonal
- Description
- Alpha Tubulin antibody (Cat. #11224-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
Submitted references CYR61 Acts as an Intracellular Microtubule-Associated Protein and Coordinates Mitotic Progression via PLK1-FBW7 Pathway.
Colchicine Blocks Abdominal Aortic Aneurysm Development by Maintaining Vascular Smooth Muscle Cell Homeostasis.
Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-κB and Keap1-Nrf2-HO-1 signaling pathways in macrophages.
Astragaloside IV attenuates renal tubule injury in DKD rats via suppression of CD36-mediated NLRP3 inflammasome activation.
Anillin contributes to prostate cancer progression through the regulation of IGF2BP1 to promote c-Myc and MAPK signaling.
Cyy-287, a novel pyrimidine-2,4-diamine derivative, efficiently mitigates inflammatory responses, fibrosis, and lipid synthesis in obesity-induced cardiac and hepatic dysfunction.
Insufficient KIF15 during porcine oocyte ageing induces HDAC6-based microtubule instability.
Edaravone Maintains AQP4 Polarity Via OS/MMP9/β-DG Pathway in an Experimental Intracerebral Hemorrhage Mouse Model.
The activation of P38MAPK Signaling Pathway Impedes the Delivery of the Cx43 to the Intercalated Discs During Cardiac Ischemia-Reperfusion Injury.
GhATL68b regulates cotton fiber cell development by ubiquitinating the enzyme required for β-oxidation of polyunsaturated fatty acids.
Inhibition of MST1 ameliorates neuronal apoptosis via GSK3β/β-TrCP/NRF2 pathway in spinal cord injury accompanied by diabetes.
Effect of CTLA-4 Inhibition on Inflammation and Apoptosis After Spinal Cord Injury.
The balance between nuclear import and export of NLRC5 regulates MHC class I transactivation.
BdTTLL3B-mediated polyglycylation is involved in the spermatogenesis in Bactrocera dorsalis.
Targeting PHGDH reverses the immunosuppressive phenotype of tumor-associated macrophages through α-ketoglutarate and mTORC1 signaling.
A novel HDAC8 inhibitor H7E exerts retinoprotective effects against glaucomatous injury via ameliorating aberrant Müller glia activation and oxidative stress.
Development and Application of the CRISPR-dcas13d-eIF4G Translational Regulatory System to Inhibit Ferroptosis in Calcium Oxalate Crystal-Induced Kidney Injury.
FTH1 overexpression using a dCasRx translation enhancement system protects the kidney from calcium oxalate crystal-induced injury.
Activation of Nrf2/HO-1 signaling pathway exacerbates cholestatic liver injury.
NEK2 contributes to radioresistance in esophageal squamous cell carcinoma by inducing protective autophagy via regulating TRIM21.
AKAP8 promotes ovarian cancer progression and antagonizes PARP inhibitor sensitivity through regulating hnRNPUL1 transcription.
Deciphering smooth muscle cell heterogeneity in atherosclerotic plaques and constructing model: a multi-omics approach with focus on KLF15/IGFBP4 axis.
Bawei Chenxiang Wan ameliorates right ventricular hypertrophy in rats with high altitude heart disease by SIRT3-HIF1α-PDK/PDH signaling pathway improving fatty acid and glucose metabolism.
ω3-PUFA alleviates neuroinflammation by upregulating miR-107 targeting PIEZO1/NFκB p65.
Lrg1 silencing attenuates ischemia-reperfusion renal injury by regulating autophagy and apoptosis through the TGFβ1- Smad1/5 signaling pathway.
Let-7b-TLR7 Signaling Axis Contributes to the Anesthesia/Surgery-Induced Cognitive Impairment.
RNA m(5)C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and promotes tumor progression in ovarian cancer.
Emodin alleviates CRS4-induced mitochondrial damage via activation of the PGC1α signaling.
LncRNA linc01194 promotes the progress of endometrial carcinoma by up-regulating SOX2 through binding to IGF2BP1.
Inhibition of HDAC6 promotes microvascular endothelial cells to phagocytize myelin debris and reduces inflammatory response to accelerate the repair of spinal cord injury.
Integrin β8 prevents pericyte-myofibroblast transition and renal fibrosis through inhibiting the TGF-β1/TGFBR1/Smad3 pathway in diabetic kidney disease.
Exercise-inducible circulating extracellular vesicle irisin promotes browning and the thermogenic program in white adipose tissue.
Expression and in vitro effect of phoenixin-14 on the porcine ovarian granulosa cells.
Physical and social environmental enrichment alleviate ferroptosis and inflammation with inhibition of TLR4/MyD88/p38MAPK pathway in chronic cerebral hypoperfusion rats.
STING activation in cardiomyocytes drives hypertrophy-associated heart failure via NF-κB-mediated inflammatory response.
Ubiquitination of cytoplasmic HMGB1 by RNF186 regulates hepatic lipophagy in non-alcoholic fatty liver disease.
SETDB1-mediated CD147-K71 di-methylation promotes cell apoptosis in non-small cell lung cancer.
LncRNA Anxa10-203 enhances Mc1r mRNA stability to promote neuropathic pain by recruiting DHX30 in the trigeminal ganglion.
Rag-GTPase-TFEB/TFE3 axis controls B cell mitochondrial fitness and humoral immunity independent of mTORC1.
USP15 facilitates the progression of bladder cancer by amplifying the activation of the NF-κB signaling pathway.
Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice.
CDKL1 potentiates the antitumor efficacy of radioimmunotherapy by binding to transcription factor YBX1 and blocking PD-L1 expression in lung cancer.
Pan-cancer analysis of DDIT4 identifying its prognostic value and function in acute myeloid leukemia.
Postweaning Development Influences Endogenous VPAC(1) Modulation of LTP Induced by Theta-Burst Stimulation: A Link to Maturation of the Hippocampal GABAergic System.
A novel method to efficiently differentiate human osteoclasts from blood-derived monocytes.
Increased extracellular matrix stiffness regulates myofibroblast transformation through induction of autophagy-mediated Kindlin-2 cytoplasmic translocation.
The roles of gut microbiome and metabolites associated with skin photoaging in mice by intestinal flora sequencing and metabolomics.
RNA modification-related genes illuminate prognostic signature and mechanism in esophageal squamous cell carcinoma.
Unraveling the molecular mechanisms of lymph node metastasis in ovarian cancer: focus on MEOX1.
Impaired Response to Mismatch Novelty in the Li(2+)-Pilocarpine Rat Model of TLE: Correlation with Hippocampal Monoaminergic Inputs.
The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness.
Kynurenine in IDO1(high) cancer cell-derived extracellular vesicles promotes angiogenesis by inducing endothelial mitophagy in ovarian cancer.
SCN5A-L256del and L1621F exhibit loss-of-function properties related to autosomal recessive congenital cardiac disorders presenting as sick sinus syndrome, dilated cardiomyopathy, and sudden cardiac death.
KIAA1429 facilitates metastasis via m6A-YTHDC1-dependent RND3 down-regulation in hepatocellular carcinoma cells.
OTUD4 promotes the progression of glioblastoma by deubiquitinating CDK1 and activating MAPK signaling pathway.
AIM2 regulates autophagy to mitigate oxidative stress in aged mice with acute liver injury.
Sphingomyelin is involved in regulating UCP1-mediated nonshivering thermogenesis.
Zinc-a2-Glycoprotein Acts as a Component of PNN to Protect Hippocampal Neurons from Apoptosis.
Myricanol attenuates sepsis-induced inflammatory responses by nuclear factor erythroid 2-related factor 2 signaling and nuclear factor kappa B/mitogen-activated protein kinase pathway via upregulating Sirtuin 1.
Dual inhibition of oxidative phosphorylation and glycolysis to enhance cancer therapy.
Combining cisplatin with Pinellia pedatisecta Schott lipid-soluble extract induces tumor immunogenic cell death in cervical cancer.
Differential innate immune responses to fowl adenovirus serotype 4 infection in Leghorn male hepatocellular and chicken embryo fibroblast cells.
GSK0660 enhances antitumor immunotherapy by reducing PD-L1 expression.
Remote Ischemic Postconditioning-Mediated Neuroprotection against Stroke by Promoting Ketone Body-Induced Ferroptosis Inhibition.
Screening of potential hub genes involved in Kidney Wilms tumor via bioinformatics analysis and experimental validation.
Base editing correction of OCRL in Lowe syndrome: ABE-mediated functional rescue in patient-derived fibroblasts.
Targeted Metabolomics of Tissue and Plasma Identifies Biomarkers in Mice with NOTCH1-Dependent T-Cell Acute Lymphoblastic Leukemia.
Terpinen-4-ol Improves Lipopolysaccharide-Induced Macrophage Inflammation by Regulating Glutamine Metabolism.
Targeting Ribosome Biogenesis as a Novel Therapeutic Approach to Overcome EMT-related Chemoresistance in Breast Cancer.
SIRT4 promotes neuronal apoptosis in models of Alzheimer's disease via the STAT2-SIRT4-mTOR pathway.
Loss of PTPRS elicits potent metastatic capability and resistance to temozolomide in glioblastoma.
Vagus nerve stimulation as a promising neuroprotection for ischemic stroke via α7nAchR-dependent inactivation of microglial NLRP3 inflammasome.
Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses.
Effects of testosterone dose on depression-like behavior among castrated adult male rats.
LncRNA AC100826.1 regulated PLCB1 to promote progression in non-small cell lung cancer.
SELENOI Functions as a Key Modulator of Ferroptosis Pathway in Colitis and Colorectal Cancer.
Inhibition of METTL3 Alleviates NLRP3 Inflammasome Activation via Increasing Ubiquitination of NEK7.
The potential role of the prolyl isomerase Pin1 during blastocyst implantation and uterine decidualization in mice.
DNA demethylase TET2-mediated reduction of HADHB expression contributes to cadmium-induced malignant progression of colorectal cancer.
Discovery of a Covalent Inhibitor That Overcame Resistance to Venetoclax in AML Cells Overexpressing BFL-1.
Discovery of Novel 2-Oxoacetamide Derivatives as B3GAT3 Inhibitors for the Treatment of Hepatocellular Carcinoma.
Racgap1 knockdown results in cells with multiple cilia due to cytokinesis failure.
Oridonin suppresses the growth of glioblastoma cells via inhibiting Hippo/YAP axis.
Sirtuin 6 protects against podocyte injury by blocking the renin-angiotensin system by inhibiting the Wnt1/β-catenin pathway.
Cysteine and glycine-rich protein 2 retards platelet-derived growth factor-BB-evoked phenotypic transition of airway smooth muscle cells by decreasing YAP/TAZ activity.
Exosomal miR-23a-3p derived from human umbilical cord mesenchymal stem cells promotes remyelination in central nervous system demyelinating diseases by targeting Tbr1/Wnt pathway.
KAN0438757, a novel PFKFB3 inhibitor, prevent the progression of severe acute pancreatitis via the Nrf2/HO-1 pathway in infiltrated macrophage.
An oncolytic system produces oxygen selectively in pancreatic tumor cells to alleviate hypoxia and improve immune activation.
Highly efficient identification of nucleocytoplasmic O-glycosylation by the TurboID-based proximity labeling method in living cells.
Nuclear translocation of Axl contributes to the malignancy of oral cancer cells.
MiR-34a functions as a tumor suppressor in oral cancer through the inhibition of the Axl/Akt/GSK-3β pathway.
PIM1 attenuates cisplatin-induced AKI by inhibiting Drp1 activation.
Arf1 GTPase Regulates Golgi-Dependent G2/M Transition and Spindle Organization in Oocyte Meiosis.
Meta-analysis identifying gut microbial biomarkers of Qinghai-Tibet Plateau populations and the functionality of microbiota-derived butyrate in high-altitude adaptation.
Excessive Mitochondrial Fission Suppresses Mucosal Repair by Impairing Butyrate Metabolism in Colonocytes.
CLIC3 interacts with NAT10 to inhibit N4-acetylcytidine modification of p21 mRNA and promote bladder cancer progression.
ChemR23 signaling ameliorates brain injury via inhibiting NLRP3 inflammasome-mediated neuronal pyroptosis in ischemic stroke.
Adipose-derived stem cell exosomes promote tumor characterization and immunosuppressive microenvironment in breast cancer.
PITPNC1 Suppress CD8(+) T cell immune function and promote radioresistance in rectal cancer by modulating FASN/CD155.
Guanosine diphosphate-mannose suppresses homologous recombination repair and potentiates antitumor immunity in triple-negative breast cancer.
Lamivudine, Doravirine, and Cabotegravir Downregulate the Expression of Human Endogenous Retroviruses (HERVs), Inhibit Cell Growth, and Reduce Invasive Capability in Melanoma Cell Lines.
Multiple reorganizations of the lateral elements of the synaptonemal complex facilitate homolog segregation in Bombyx mori oocytes.
TC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis.
Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia.
ZDHHC5-mediated S-palmitoylation of FAK promotes its membrane localization and epithelial-mesenchymal transition in glioma.
Role of histone variants H2BC1 and H2AZ.2 in H2AK119ub nucleosome organization and Polycomb gene silencing.
YBX1 promotes type H vessel-dependent bone formation in an m5C-dependent manner.
Echinacoside inhibits colorectal cancer metastasis via modulating the gut microbiota and suppressing the PI3K/AKT signaling pathway.
Deep learning enables the discovery of a novel cuproptosis-inducing molecule for the inhibition of hepatocellular carcinoma.
Targeting ZDHHC21/FASN axis for the treatment of diffuse large B-cell lymphoma.
Epigallocatechin-3-gallate promotes wound healing response in diabetic mice by activating keratinocytes and promoting re-epithelialization.
MKP-1 regulates the inflammatory activation of microglia against Alzheimer's disease.
Dihydroxyacetone phosphate accumulation leads to podocyte pyroptosis in diabetic kidney disease.
A novel hydrogen sulfide donor reduces neuroinflammation and seizures by activating ATP-sensitive potassium channels.
Hyaluronic Acid-Based Reactive Oxygen Species-Responsive Multifunctional Injectable Hydrogel Platform Accelerating Diabetic Wound Healing.
WWP2 protects against sepsis-induced cardiac injury through inhibiting cardiomyocyte ferroptosis.
BHLHE40 Inhibits Ferroptosis in Pancreatic Cancer Cells via Upregulating SREBF1.
G3BP1 and SLU7 Jointly Promote Immune Evasion by Downregulating MHC-I via PI3K/Akt Activation in Bladder Cancer.
DSPE-PEG(2000)-methotrexate nanoparticles encapsulating phenobarbital sodium kill cancer cells by inducing pyroptosis.
Transcriptome-Wide N6-Methyladenosine Alternations in Pulmonary Arteries of Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats and Novel Therapeutic Targets.
Molecular mechanism underlying miR-204-5p regulation of adipose-derived stem cells differentiation into cells from three germ layers.
LINC02561 promotes metastasis in HCC via HIF1-α/NDRG1/UPF1 axis.
Renal Endocytic Regulation of Vitamin D Metabolism during Maturation and Aging in Laying Hens.
Solobacterium moorei promotes the progression of adenomatous polyps by causing inflammation and disrupting the intestinal barrier.
Synthesis and In Vitro Antitumor Activity Evaluation of Gefitinib-1,2,3-Triazole Derivatives.
Metabolites that feed upper glycolytic branches support glucose independent human cytomegalovirus replication.
ANLN Promotes the Proliferation and Migration of Gallbladder Cancer Cells via STRA6-Mediated Activation of PI3K/AKT Signaling.
Empagliflozin and liraglutide ameliorate HFpEF in mice via augmenting the Erbb4 signaling pathway.
TAGLN2 targeted control of ARPC5-mediated activation of the MEK/ERK signaling pathway influences the proliferation, invasion, and metastasis of pancreatic cancer cells.
Therapeutic potential of flavopiridol in diabetic retinopathy: Targeting DDX58.
Characterization of Novel PHEX Variants in X-linked Hypophosphatemic Rickets and Genotype-PHEX Activity Correlation.
SPTBN2 suppresses ferroptosis in NSCLC cells by facilitating SLC7A11 membrane trafficking and localization.
Pimpinellin ameliorates macrophage inflammation by promoting RNF146-mediated PARP1 ubiquitination.
Excessive processing and acetylation of OPA1 aggravate age-related hearing loss via the dysregulation of mitochondrial dynamics.
Platycodon grandiflorus polysaccharide inhibits the inflammatory response of 3D4/21 cells infected with PCV2.
Tangshen Formula alleviates inflammatory injury against aged diabetic kidney disease through modulating gut microbiota composition and related amino acid metabolism.
The role of adhesion molecules in osteocalcin-induced effects on glucose and lipid metabolism in adipocytes.
The regulatory role of the apelin/APJ axis in scarring: Identification of upstream and downstream mechanisms.
LCP1-mediated cytoskeleton alterations involve in arsenite-triggered malignant phenotype of human immortalized prostate stromal cells.
Rapamycin protects Sertoli cells against BPA-induced autophagy disorders.
Histone deacetylase 6 suppression of renal tubular epithelial cell promotes interstitial mineral deposition via alpha-tubulin acetylation.
Homozygous variant in COQ7 causes autosomal recessive hereditary spastic paraplegia.
The surface morphology of Atractylodes macrocephala polysaccharide and its inhibitory effect on PCV2 replication.
Miz1 represses type I interferon production and limits viral clearance during influenza A virus infection.
Single-cell systems pharmacology identifies development-driven drug response and combination therapy in B cell acute lymphoblastic leukemia.
Identification of immune-associated biomarker for predicting lung adenocarcinoma: bioinformatics analysis and experiment verification of PTK6.
Pyxinol Fatty Acid Ester Derivatives J16 against AKI by Selectively Promoting M1 Transition to M2c Macrophages.
Shank3 deficiency elicits autistic-like behaviors by activating p38α in hypothalamic AgRP neurons.
Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction.
Prognostic and Immunotherapeutic Predictive Value of CAD Gene in Hepatocellular Carcinoma: Integrated Bioinformatics and Experimental Analysis.
Anti-hepatocellular carcinoma activity of Sorbaria sorbifolia by regulating VEGFR and c-Met/apoptotic pathway.
Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion.
Discovery of gefitinib-1,2,3-triazole derivatives against lung cancer via inducing apoptosis and inhibiting the colony formation.
Bulk and single-cell RNA sequencing analysis with 101 machine learning combinations reveal neutrophil extracellular trap involvement in hepatic ischemia-reperfusion injury and early allograft dysfunction.
Fatty liver disease protective MTARC1 p.A165T variant reduces the protein stability of MTARC1.
Single-cell transcriptomics dissects the transcriptome alterations of hematopoietic stem cells in myelodysplastic neoplasms.
TSHR signaling promotes hippocampal dependent memory formation through modulating Wnt5a/β-catenin mediated neurogenesis.
HIF1A transcriptional regulation of COX4I2 impacts angiogenesis in pheochromocytoma.
Human mesenchymal stem cells derived exosomes improve ovarian function in chemotherapy-induced premature ovarian insufficiency mice by inhibiting ferroptosis through Nrf2/GPX4 pathway.
Programmable RNA 5-methylcytosine (m5C) modification of cellular RNAs by dCasRx conjugated methyltransferase and demethylase.
METTL3 recruiting M2-type immunosuppressed macrophages by targeting m6A-SNAIL-CXCL2 axis to promote colorectal cancer pulmonary metastasis.
The role of miR-222-2p in exosomes secreted by hexavalent chromium-induced premature senescent hepatocytes as a SASP component.
SH2B1 Tunes Hippocampal ERK Signaling to Influence Fluid Intelligence in Humans and Mice.
Loss of Lactate/Proton Monocarboxylate Transporter 4 Induces Ferroptosis via the AMPK/ACC Pathway and Inhibition of Autophagy on Human Bladder Cancer 5637 Cell Line.
Aldolase A Promotes Colorectal Cancer Progression through Targeting COPS6 and Regulating MAPK Signaling Pathway.
Quantitative Measurement of Transthyretin Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Chronic stress promotes colorectal cancer progression by enhancing glycolysis through β2-AR/CREB1 signal pathway.
Phosphorylation by IKKβ Promotes the Degradation of HMGCL via NEDD4 in Lung Cancer.
Epileptiform activity influences theta-burst induced LTP in the adult hippocampus: a role for synaptic lipid raft disruption in early metaplasticity?
Omarigliptin Protects the Integrity of the Blood-Brain Barrier After Intracerebral Hemorrhage in Mice.
Cardiolipin externalization mediates prion protein (PrP) peptide 106-126-associated mitophagy and mitochondrial dysfunction.
Multi-omics analysis reveals the involvement of origin recognition complex subunit 6 in tumor immune regulation and malignant progression.
MIR222HG attenuates macrophage M2 polarization and allergic inflammation in allergic rhinitis by targeting the miR146a-5p/TRAF6/NF-κB axis.
Crosstalk of RNA methylation writers defines tumor microenvironment and alisertib resistance in breast cancer.
Sperm morphological abnormalities in autosomal dominant polycystic kidney disease are associated with the Hippo signaling pathway via PC1.
Norbergenin prevents LPS-induced inflammatory responses in macrophages through inhibiting NFκB, MAPK and STAT3 activation and blocking metabolic reprogramming.
Establishment of a porcine bronchial epithelial cell line and its application to study innate immunity in the respiratory epithelium.
Resolvin D1/N-formyl peptide receptor 2 ameliorates paclitaxel-induced neuropathic pain through the activation of IL-10/Nrf2/HO-1 pathway in mice.
Integrative analysis of the role of BOLA2B in human pan-cancer.
ATRX loss suppresses the type I interferon response in sarcoma cells through chromatin remodeling.
Lactate-mediated Fascin protrusions promote cell adhesion and migration in cervical cancer.
BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution.
Targeting plasmodium α-tubulin-1 to block malaria transmission to mosquitoes.
System analysis based on the migration- and invasion-related gene sets identifies the infiltration-related genes of glioma.
YAP1 affects the prognosis through the regulation of stemness in endometrial cancer.
The novel role of LDHA/LDHB in the prognostic value and tumor-immune infiltration in clear cell renal cell carcinoma.
RNA-seq reveals Nup62 as a potential regulator for cell division after traumatic brain injury in mice hippocampus.
Differences in histomorphology and expression of key lipid regulated genes of four adipose tissues from Tibetan pigs.
α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure.
Electroacupuncture-Modulated MiR-106b-5p Expression Enhances Autophagy by Targeting Beclin-1 to Promote Motor Function Recovery After Spinal Cord Injury in Rats.
DWL-4-140: A allene small molecule targeting STING that alleviates lupus-like phenotype in Trex1(-/-) mice.
The p65-LOC727924-miR-26a/KPNA3-p65 regulatory loop mediates vasoactive intestinal peptide effects on osteoarthritis chondrocytes.
Inhibition of TCA cycle improves the anti-PD-1 immunotherapy efficacy in melanoma cells via ATF3-mediated PD-L1 expression and glycolysis.
FTO alleviates cerebral ischemia/reperfusion-induced neuroinflammation by decreasing cGAS mRNA stability in an m6A-dependent manner.
Osteogenic microenvironment affects palatal development through glycolysis.
UBQLN2 and HSP70 participate in Parkin-mediated mitophagy by facilitating outer mitochondrial membrane rupture.
A natural chalcone cardamonin inhibits necroptosis and ameliorates dextran sulfate sodium (DSS)-induced colitis by targeting RIPK1/3 kinases.
Centrosome linker diversity and its function in centrosome clustering and mitotic spindle formation.
IGF1R-phosphorylated PYCR1 facilitates ELK4 transcriptional activity and sustains tumor growth under hypoxia.
Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5.
Depletion of G9A attenuates imiquimod-induced psoriatic dermatitis via targeting EDAR-NF-κB signaling in keratinocyte.
Cell Cycle Reactivation, at the Start of Neurodegeneration, Induced by Forskolin and Aniline in Differentiated Neuroblastoma Cells.
Human umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice.
Metabolic classification suggests the GLUT1/ALDOB/G6PD axis as a therapeutic target in chemotherapy-resistant pancreatic cancer.
Piper nigrum Extract Inhibits the Growth of Human Colorectal Cancer HT-29 Cells by Inducing p53-Mediated Apoptosis.
Zymosan A Improved Doxorubicin-Induced Ventricular Remodeling by Evoking Heightened Cardiac Inflammatory Responses and Healing in Mice.
GPR65 inhibits human trophoblast cell adhesion through upregulation of MYLK and downregulation of fibronectin via cAMP-ERK signaling in a low pH environment.
Estrogen receptor alpha regulates uterine epithelial lineage specification and homeostasis.
Integrated clustering signature of genomic heterogeneity, stemness and tumor microenvironment predicts glioma prognosis and immunotherapy response.
N-methylpiperazine-diepoxyovatodiolide ameliorates peritoneal fibrosis via suppressing TGF-β/Smad and JAK/STAT signaling pathway.
Fisetin treatment alleviates kidney injury in mice with diabetes-exacerbated atherosclerosis through inhibiting CD36/fibrosis pathway.
SEMA3B-AS1 suppresses colorectal carcinoma progression by inhibiting Semaphorin 3B-dependent VEGF signaling pathway activation.
3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis.
Oxidative stress and inflammation are mediated via aryl hydrocarbon receptor signalling in idiopathic membranous nephropathy.
Derlin-1 ameliorates nonalcoholic hepatic steatosis by promoting ubiquitylation and degradation of FABP1.
Hepatitis B virus-related intrahepatic cholangiocarcinoma originates from hepatocytes.
Atorvastatin rescues vascular endothelial injury in hypertension by WWP2-mediated ubiquitination and degradation of ATP5A.
Improved anti-tumor activity of fluorinated camptothecin derivatives 9-fluorocamptothecin and 7-ethyl-9-fluorocamptothecin on hepatocellular carcinoma by targeting topoisomerase I.
MicroMagnify: A Multiplexed Expansion Microscopy Method for Pathogens and Infected Tissues.
Spatiotemporal Regulation of De Novo and Salvage Purine Synthesis during Brain Development.
Broad-spectrum vaccine via combined immunization routes triggers potent immunity to SARS-CoV-2 and its variants.
The Antihypertensive Guanabenz Exacerbates Integrated Stress Response and Disrupts the Brain Circadian Clock.
HLA-DPA1 overexpression inhibits cancer progression, reduces resistance to cisplatin, and correlates with increased immune infiltration in lung adenocarcinoma.
Deacetylation of ACO2 Is Essential for Inhibiting Bombyx mori Nucleopolyhedrovirus Propagation.
IGF2BP2 acts as a m(6)A modification regulator in laryngeal squamous cell carcinoma through facilitating CDK6 mRNA stabilization.
Stattic ameliorates the cecal ligation and puncture-induced cardiac injury in septic mice via IL-6-gp130-STAT3 signaling pathway.
Injectable microenvironment-responsive hydrogels with redox-activatable supramolecular prodrugs mediate ferroptosis-immunotherapy for postoperative tumor treatment.
A new ferrocene derivative blocks K-Ras localization and function by oxidative modification at His95.
The crucial role that hippocampus Cyclooxygenase-2 plays in memory.
Inhibition of TMEM16A improves cisplatin-induced acute kidney injury via preventing DRP1-mediated mitochondrial fission.
Decrease of Cellular Communication Network Factor 1 (CCN1) Attenuates PTZ-Kindled Epilepsy in Mice.
Nuclear translocation of PKM2 mediates keratinocyte metabolic reprogramming in psoriasis.
Photoactivatable base editors for spatiotemporally controlled genome editing in vivo.
USP51 facilitates colorectal cancer stemness and chemoresistance by forming a positive feed-forward loop with HIF1A.
Enamel defects of Axenfeld-Rieger syndrome and the role of PITX2 in its pathogenesis.
Deubiquitinase inhibitor PR-619 potentiates colon cancer immunotherapy by inducing ferroptosis.
Knockdown of repulsive guidance molecule a promotes polarization of microglia into an anti-inflammatory phenotype after oxygen-glucose deprivation-reoxygenation in vitro.
Design and synthesis of 1H-pyrazolo[3,4-d]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors.
Sanguisorba officinalis ethyl acetate extract attenuates ulcerative colitis through inhibiting PI3K-AKT/NF-κB/ STAT3 pathway uncovered by single-cell RNA sequencing.
ADAMTS12 promotes oxaliplatin chemoresistance and angiogenesis in gastric cancer through VEGF upregulation.
Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain.
Defective branched-chain amino acid catabolism in dorsal root ganglia contributes to mechanical pain.
PFKP confers chemoresistance by upregulating ABCC2 transporter in non-small cell lung cancer.
HDAC1-Mediated lncRNA Stimulatory Factor of Follicular Development to Inhibit the Apoptosis of Granulosa Cells and Regulate Sexual Maturity through miR-202-3p-COX1 Axis.
METTL9-SLC7A11 axis promotes hepatocellular carcinoma progression through ferroptosis inhibition.
CCDC127 regulates lipid droplet homeostasis by enhancing mitochondria-ER contacts.
Reduction of p11 in dorsal raphe nucleus serotonergic neurons mediates depression-like behaviors.
STIM2 regulates NMDA receptor endocytosis that is induced by short-term NMDA receptor overactivation in cortical neurons.
Circular RNA ZBTB46 depletion alleviates the progression of Atherosclerosis by regulating the ubiquitination and degradation of hnRNPA2B1 via the AKT/mTOR pathway.
Herbal medicine formula Huazhuo Tiaozhi granule ameliorates dyslipidaemia via regulating histone lactylation and miR-155-5p biogenesis.
A comprehensive analysis of SLC25A1 expression and its oncogenic role in pan-cancer.
Exercise improves cognitive dysfunction and neuroinflammation in mice through Histone H3 lactylation in microglia.
Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice.
Regulation of the Hippo/YAP axis by CXCR7 in the tumorigenesis of gastric cancer.
Accelerating Wound Closure With Metrnl in Normal and Diabetic Mouse Skin.
Morusinol Extracted from Morus alba Inhibits Cell Proliferation and Induces Autophagy via FOXO3a Nuclear Accumulation-Mediated Cholesterol Biosynthesis Obstruction in Colorectal Cancer.
Cholesterol mediated ferroptosis suppression reveals essential roles of Coenzyme Q and squalene.
Circular RNA transcriptome across multiple tissues reveal skeletal muscle-specific circPSME4 regulating myogenesis.
cGAS-STING signaling pathway promotes hypoxia-induced renal fibrosis by regulating PFKFB3-mediated glycolysis.
A phosphoglycerate mutase 1 allosteric inhibitor overcomes drug resistance to EGFR-targeted therapy via disrupting IL-6/JAK2/STAT3 signaling pathway in lung adenocarcinoma.
Naringenin in Si-Ni-San formula inhibits chronic psychological stress-induced breast cancer growth and metastasis by modulating estrogen metabolism through FXR/EST pathway.
OTUB1 Catalytic-Independently Deubiquitinates TGFBI and Mediates the Angiogenesis in Infantile Hemangioma by Regulating Glycolysis.
Splicing factor SNRPA associated with microvascular invasion promotes hepatocellular carcinoma metastasis through activating NOTCH1/Snail pathway and is mediated by circSEC62/miR-625-5p axis.
Rational design of a polysaccharide-based viral mimicry nanocomplex for potent gene silencing in inflammatory tissues.
Bioinformatics analysis of ferroptosis-related gene AKR1C3 as a potential biomarker of asthma and its identification in BEAS-2B cells.
Role of Type I Cannabinoid Receptor in Sensory Neurons in Psoriasiform Skin Inflammation and Pruritus.
Down-regulation of WWP2 aggravates Type 2 diabetes mellitus-induced vascular endothelial injury through modulating ubiquitination and degradation of DDX3X.
MYO10 regulates genome stability and cancer inflammation through mediating mitosis.
VEGFR-3 signaling restrains the neuron-macrophage crosstalk during neurotropic viral infection.
Transcriptional coactivation by EHMT2 restricts glucocorticoid-induced insulin resistance in a study with male mice.
Dihydrotrichodimerol Purified from the Marine Fungus Acremonium citrinum Prevents NAFLD by Targeting PPARα.
Side population cells derived from hUCMSCs and hPMSCs could inhibit the malignant behaviors of Tn(+) colorectal cancer cells from modifying their O-glycosylation status.
Cardamonin targets KEAP1/NRF2 signaling for protection against atherosclerosis.
CEBPG suppresses ferroptosis through transcriptional control of SLC7A11 in ovarian cancer.
Macrophages maintain mammary stem cell activity and mammary homeostasis via TNF-α-PI3K-Cdk1/Cyclin B1 axis.
Inhibition of Oocyte Maturation by Follicular Extracellular Vesicles of Nonhyperandrogenic PCOS Patients Requiring IVF.
Ginsenoside Rb1 promotes the activation of PPARα pathway via inhibiting FADD to ameliorate heart failure.
USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1.
Nanoemulsions of Hydroxysafflor Yellow A for Enhancing Physicochemical and In Vivo Performance.
Photoaging of polystyrene microspheres causes oxidative alterations to surface physicochemistry and enhances airway epithelial toxicity.
Upregulation of LPGAT1 Enhances Lung Adenocarcinoma Proliferation.
Effect of Sublethal Concentrations of Metal Nanomaterials on Cell Energy Metabolism.
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
NETs promote ROS production to induce human amniotic epithelial cell apoptosis via ERK1/2 signaling in spontaneous preterm birth.
RAB7A GTPase Is Involved in Mitophagosome Formation and Autophagosome-Lysosome Fusion in N2a Cells Treated with the Prion Protein Fragment 106-126.
SARS-CoV-2 Z-RNA activates the ZBP1-RIPK3 pathway to promote virus-induced inflammatory responses.
Transportin 1 is a major nuclear import receptor of the nitric oxide synthase interacting protein.
Artesunate delays the dysfunction of age-related intestinal epithelial barrier by mitigating endoplasmic reticulum stress/unfolded protein response.
Pan-HDAC inhibitors augment IL2-induced proliferation of NK cells via the JAK2-STAT5B signaling pathway.
miR-330-3p alleviates the progression of atherosclerosis by downregulating AQP9.
A splicing silencer in SMN2 intron 6 is critical in spinal muscular atrophy.
MicroMagnify: a multiplexed expansion microscopy method for pathogens and infected tissues.
DNAJB7 is dispensable for male fertility in mice.
LncRNA SLC25A21-AS1 increases the chemosensitivity and inhibits the progression of ovarian cancer by upregulating the expression of KCNK4.
Polynucleotide phosphorylase protects against renal tubular injury via blocking mt-dsRNA-PKR-eIF2α axis.
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.
Baitouweng decoction alleviates dextran sulfate sodium-induced ulcerative colitis by suppressing leucine-related mTORC1 signaling and reducing oxidative stress.
p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.
The role of small GTPases in bisphenol AF-induced multinucleation in comparison with dibutyl phthalate in the male germ cells.
Choroid Plexus Modulates Subventricular Zone Adult Neurogenesis and Olfaction Through Secretion of Small Extracellular Vesicles.
Integrated proteomic and phosphoproteomic analysis for characterization of colorectal cancer.
Reduced inhibitory and excitatory input onto parvalbumin interneurons mediated by perineuronal net might contribute to cognitive impairments in a mouse model of sepsis-associated encephalopathy.
Necroptosis of macrophage is a key pathological feature in biliary atresia via GDCA/S1PR2/ZBP1/p-MLKL axis.
Accumulated cholesterol protects tumours from elevated lipid peroxidation in the microenvironment.
METTL1/WDR4-mediated tRNA m(7)G modification and mRNA translation control promote oncogenesis and doxorubicin resistance.
Magnify is a universal molecular anchoring strategy for expansion microscopy.
Excessive ER-phagy contributes to ochratoxin A-induced apoptosis.
DBP induced autophagy and necrotic apoptosis in HepG2 cells via the mitochondrial damage pathway.
An integrated in vitro/in silico approach to assess the anti-androgenic potency of isobavachin.
5'-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor 4A-I.
Bone marrow mesenchymal stem cell-derived exosomes reduce insulin resistance and obesity in mice via the PI3K/AKT signaling pathway.
Moshen granule ameliorates membranous nephropathy by blocking intrarenal renin-angiotensin system signalling via the Wnt1/β-catenin pathway.
Pan-cancer analysis of Homeobox B9 as a predictor for prognosis and immunotherapy in human tumors.
The potential mechanism of qinghua quyu jianpi decoction in the treatment of ulcerative colitis based on network pharmacology and experimental validation.
Tumor-secreted IFI35 promotes proliferation and cytotoxic activity of CD8(+) T cells through PI3K/AKT/mTOR signaling pathway in colorectal cancer.
Increased glucose availability sensitizes pancreatic cancer to chemotherapy.
An integrated bioinformatic investigation of focal adhesion-related genes in glioma followed by preliminary validation of COL1A2 in tumorigenesis.
Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice.
Senescent immune cells accumulation promotes brown adipose tissue dysfunction during aging.
SMYD2 inhibition-mediated hypomethylation of Ku70 contributes to impaired nonhomologous end joining repair and antitumor immunity.
OTUD7B Activates Wnt Signaling Pathway through the Interaction with LEF1.
miR-31-mediated local translation at the mitotic spindle is important for early development.
Efficient correction of ABCA4 variants by CRISPR-Cas9 in hiPSCs derived from Stargardt disease patients.
Yi-Shen-Xie-Zhuo formula alleviates cisplatin-induced AKI by regulating inflammation and apoptosis via the cGAS/STING pathway.
An O-GlcNAc transferase pathogenic variant linked to intellectual disability affects pluripotent stem cell self-renewal.
DR1-CSE/H(2)S pathway upregulates autophagy and inhibits H9C2 cells damage induced by high glucose.
Enhanced BCAT1 activity and BCAA metabolism promotes RhoC activity in cancer progression.
Macrophage scavenger receptor A1 antagonizes abdominal aortic aneurysm via upregulating IRG1.
ZCCHC3 is a stress granule zinc knuckle protein that strongly suppresses LINE-1 retrotransposition.
PPARγ inhibited tumor immune escape by inducing PD-L1 autophagic degradation.
PPARγ agonist pioglitazone enhances colorectal cancer immunotherapy by inducing PD-L1 autophagic degradation.
LncRNA DANCR deficiency promotes high glucose-induced endothelial to mesenchymal transition in cardiac microvascular cells via the FoxO1/DDAH1/ADMA signaling pathway.
Mitigation of non-alcoholic steatohepatitis via recombinant Orosomucoid 2, an acute phase protein modulating the Erk1/2-PPARγ-Cd36 pathway.
Suppression of TREX1 deficiency-induced cellular senescence and interferonopathies by inhibition of DNA damage response.
NVS-ZP7-4 inhibits hepatocellular carcinoma tumorigenesis and promotes apoptosis via PI3K/AKT signaling.
Quantitative Measurement of Secretory Protein Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Schisandrin C enhances cGAS-STING pathway activation and inhibits HBV replication.
PTRF-IL33-ZBP1 signaling mediating macrophage necroptosis contributes to HDM-induced airway inflammation.
Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle.
The Effect of MSTN Mutation on Bile Acid Metabolism and Lipid Metabolism in Cattle.
A novel variant in the FBP1 gene causes fructose-1,6-bisphosphatase deficiency through increased ubiquitination.
SIRT2 promotes cell proliferation and migration through mediating ERK1/2 activation and lactosylceramide accumulation in prostate cancer.
Site-specific ubiquitination of VDAC1 restricts its oligomerization and mitochondrial DNA release in liver fibrosis.
Formin protein DIAPH1 positively regulates PD-L1 expression and predicts the therapeutic response to anti-PD-1/PD-L1 immunotherapy.
Translational control of murine adiponectin expression by an upstream open reading frame element.
Enhanced BPGM/2,3-DPG pathway activity suppresses glycolysis in hypoxic astrocytes via FIH-1 and TET2.
Kaempferol attenuates doxorubicin-induced renal tubular injury by inhibiting ROS/ASK1-mediated activation of the MAPK signaling pathway.
PIM1 attenuates renal ischemia-reperfusion injury by inhibiting ASK1-JNK/P38.
Myeloid-derived suppressor cells ameliorate liver mitochondrial damage to protect against autoimmune hepatitis by releasing small extracellular vesicles.
Tumor-intrinsic IRE1α signaling controls protective immunity in lung cancer.
NAMPT inhibition reduces macrophage inflammation through the NAD+/PARP1 pathway to attenuate liver ischemia-reperfusion injury.
MitoQ Protects Ovarian Organoids against Oxidative Stress during Oogenesis and Folliculogenesis In Vitro.
Qi Gong Wan ameliorates adipocyte hypertrophy and inflammation in adipose tissue in a PCOS mouse model through the Nrf2/HO-1/Cyp1b1 pathway: Integrating network pharmacology and experimental validation in vivo.
Adipose-specific deletion of the cation channel TRPM7 inhibits TAK1 kinase-dependent inflammation and obesity in male mice.
Role of NF-κB in lead exposure-induced activation of astrocytes based on bioinformatics analysis of hippocampal proteomics.
TAT Nanobody Exerts Antiviral Effect against PRRSV In Vitro by Targeting Viral Nucleocapsid Protein.
Niche stiffness sustains cancer stemness via TAZ and NANOG phase separation.
Recombinant human angiotensin-converting enzyme 2 plays a protective role in mice with sepsis-induced cardiac dysfunction through multiple signaling pathways dependent on converting angiotensin II to angiotensin 1-7.
Tissue inhibitor of metalloproteinase-4 deletion in mice impacts maternal cardiac function during pregnancy and postpartum.
Daucosterol Alleviates Alcohol-Induced Hepatic Injury and Inflammation through P38/NF-κB/NLRP3 Inflammasome Pathway.
A novel role of Fas in delaying cellular senescence.
Knockout of TSC2 in Nav1.8+ neurons predisposes to the onset of normal weight obesity.
The TGF-β/Smad(2/3) signaling pathway is involved in Musashi2-induced invasion and metastasis of colorectal cancer.
Dual Antioxidant DH-217 Mitigated Cerebral Ischemia-Reperfusion Injury by Targeting IKKβ/Nrf2/HO-1 Signal Axis.
Ubiquitin-specific protease 24 promotes EV71 infection by restricting K63-linked polyubiquitination of TBK1.
Activation of Nrf2 signaling by 4-octyl itaconate attenuates the cartilaginous endplate degeneration by inhibiting E3 ubiquitin ligase ZNF598.
Small ankyrin 1 (sANK1) promotes docetaxel resistance in castration-resistant prostate cancer cells by enhancing oxidative phosphorylation.
Effects of the CDC10 (Septin 7) Gene on the Proliferation and Differentiation of Bovine Intramuscular Preadipocyte and 3T3-L1 Cells.
Application of deep generative model for design of Pyrrolo[2,3-d] pyrimidine derivatives as new selective TANK binding kinase 1 (TBK1) inhibitors.
Development of highly potent and specific AKR1C3 inhibitors to restore the chemosensitivity of drug-resistant breast cancer.
Supplementation with α-ketoglutarate improved the efficacy of anti-PD1 melanoma treatment through epigenetic modulation of PD-L1.
Arthrocolins Synergizing with Fluconazole Inhibit Fluconazole-Resistant Candida albicans by Increasing Riboflavin Metabolism and Causing Mitochondrial Dysfunction and Autophagy.
ARL9 is upregulated and serves as a biomarker for a poor prognosis in colon adenocarcinoma.
PAK2 is essential for chromosome alignment in metaphase I oocytes.
RBX1 regulates PKM alternative splicing to facilitate anaplastic thyroid carcinoma metastasis and aerobic glycolysis by destroying the SMAR1/HDAC6 complex.
Differential effects of the LncRNA RNF157-AS1 on epithelial ovarian cancer cells through suppression of DIRAS3- and ULK1-mediated autophagy.
Nanodrug rescues liver fibrosis via synergistic therapy with H(2)O(2) depletion and Saikosaponin b1 sustained release.
N(6)-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis.
Exendin-4 alleviates myocardial ischemia reperfusion injury by enhancing autophagy through promoting nuclear translocation of TFEB.
Development of a series of quinazoline-2,5-diamine derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors.
Rationally designed donepezil-based hydroxamates modulate Sig-1R and HDAC isoforms to exert anti-glioblastoma effects.
Sulforaphane attenuates microglia-mediated neuronal damage by down-regulating the ROS/autophagy/NLRP3 signal axis in fibrillar Aβ-activated microglia.
MAD2B Blunts Chronic Unpredictable Stress and Corticosterone Stimulation-Induced Depression-Like Behaviors in Mice.
Luteoloside Induces G0/G1 Phase Arrest of Neuroblastoma Cells by Targeting p38 MAPK.
Deciphering the underlying wound healing mechanisms of Streptocaulon juventas (Lour.) Merr. by integrating network pharmacology, transcriptomics, and experimental validation.
Bumetanide Rescues Aquaporin-4 Depolarization via Suppressing β-Dystroglycan Cleavage and Provides Neuroprotection in Rat Retinal Ischemia-Reperfusion Injury.
SIRT3-dependent mitochondrial redox homeostasis mitigates CHK1 inhibition combined with gemcitabine treatment induced cardiotoxicity in hiPSC-CMs and mice.
FSIP1 enhances the therapeutic sensitivity to CDK4/6 inhibitors in triple-negative breast cancer patients by activating the Nanog pathway.
Hawthorn leaves flavonoids attenuate cardiac remodeling induced by simulated microgravity.
PPARβ/δ activation protects against hepatic ischaemia-reperfusion injury.
The Lnc-RNA APPAT Suppresses Human Aortic Smooth Muscle Cell Proliferation and Migration by Interacting With MiR-647 and FGF5 in Atherosclerosis.
A novel homozygous Y140X mutation of ISG15 causes diverse type I interferonopathies in sibling patients with cutaneous lesions or recurrent parenchymal pneumonia.
CoCl(2) -triggered pseudohypoxic stress induces proteasomal degradation of SIRT4 via polyubiquitination of lysines K78 and K299.
Diabetic and nondiabetic BMSC-derived exosomes affect bone regeneration via regulating miR-17-5p/SMAD7 axis.
Bone Marrow-Derived GCA(+) Immune Cells Drive Alzheimer's Disease Progression.
Inhibition of CK2/ING4 Pathway Facilitates Non-Small Cell Lung Cancer Immunotherapy.
Colchicine Attenuates Microvascular Obstruction after Myocardial Ischemia-Reperfusion Injury by Inhibiting the Proliferation of Neutrophil in Bone Marrow.
SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation.
FT895 Impairs Mitochondrial Function in Malignant Peripheral Nerve Sheath Tumor Cells.
Aberrant epithelial cell interaction promotes esophageal squamous-cell carcinoma development and progression.
A positive feedback circuit driven by m(6)A-modified circular RNA facilitates colorectal cancer liver metastasis.
TMEM44-AS1 promotes esophageal squamous cell carcinoma progression by regulating the IGF2BP2-GPX4 axis in modulating ferroptosis.
Squalene epoxidase promotes breast cancer progression by regulating CCNB1 protein stability.
Ubiquitin-Like Protein FAT10 Promote Colorectal Cancer Progression by Affecting the Ubiquitination of Capn4.
OGG1 aggravates renal ischemia-reperfusion injury by repressing PINK1-mediated mitophagy.
CCE and EODF as two distinct non-shivering thermogenesis models inducing weight loss.
CNTN1 in the Nucleus Accumbens is Involved in Methamphetamine-Induced Conditioned Place Preference in Mice.
Sanggenon C inhibits cell proliferation and induces apoptosis by regulating the MIB1/DAPK1 axis in glioblastoma.
Role of FBXL5 in redox homeostasis and spindle assembly during oocyte maturation in mice.
Exogenous hydrogen sulfide alleviates hepatic endoplasmic reticulum stress via SIRT1/FoxO1/PCSK9 pathway in NAFLD.
Dynamic Landscapes of tRNA Transcriptomes and Translatomes in Diverse Mouse Tissues.
Three-in-One Oncolytic Adenovirus System Initiates a Synergetic Photodynamic Immunotherapy in Immune-Suppressive Cholangiocarcinoma.
A new class of potent liver injury protective compounds: Structural elucidation, total synthesis and bioactivity study.
PPARγ agonist inhibits c-Myc-mediated colorectal cancer tumor immune escape.
Augmenter of liver regeneration promotes drug resistance of acute lymphoblastic leukemia through the alteration of mitochondrial functions and the inhibition of the mitochondrial apoptosis pathway.
Identification and Screening of Potential ACE2 Activating Peptides from Soybean Protein Isolate Hydrolysate against Ang II-Induced Endothelial Dysfunction.
Intermittent dietary methionine deprivation facilitates tumoral ferroptosis and synergizes with checkpoint blockade.
Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8(+) T cell exhaustion via TRIM14-IFN-β axis.
Smooth muscle liver kinase B1 inhibits foam cell formation and atherosclerosis via direct phosphorylation and activation of SIRT6.
Neuroprotection of β-caryophyllene against cerebral ischemia/reperfusion injury by inhibiting P38 MAPK/NLRP3 signaling pathway.
HOXA11 promotes lymphatic metastasis of gastric cancer via transcriptional activation of TGFβ1.
GM-CSF receptor/SYK/JNK/FOXO1/CD11c signaling promotes atherosclerosis.
Characterization of the Effects of Host p53 and Fos on Gallid Alpha Herpesvirus 1 Replication.
Different levels of autophagy induced by transient serum starvation regulate metabolism and differentiation of porcine skeletal muscle satellite cells.
CRISPR screen identifies GATAD1 as a synthetic lethal target with CDK4/6 inhibitors in estrogen receptor-positive breast cancer.
Saponin extract from Achyranthes bidentata Blume alleviates disuse-induced muscle atrophy through PI3K/Akt signaling pathway.
Houpo paiqi mixture promotes intestinal motility in constipated rats by modulating gut microbiota and activating 5-HT-cAMP-PKA signal pathway.
Chemokine receptor CXCR7 activates Aurora Kinase A and promotes neuroendocrine prostate cancer growth.
A cell-autonomous mechanism regulates BCAA catabolism in white adipocytes and systemic metabolic balance.
Lanthanum Chloride Induces Axon Abnormality Through LKB1-MARK2 and LKB1-STK25-GM130 Signaling Pathways.
Kaempferol promotes melanogenesis and reduces oxidative stress in PIG1 normal human skin melanocytes.
Geranylgeranylacetone-induced heat shock protein70 expression reduces retinal ischemia-reperfusion injury through PI3K/AKT/mTOR signaling.
Mice with the Rab10 T73V mutation exhibit anxiety-like behavior and alteration of neuronal functions in the striatum.
Growth differentiation factor 15 is dispensable for acetaminophen-induced liver injury in mice.
Novel Self-Assembled Multifunctional Nanoprobes for Second-Near-Infrared-Fluorescence-Image-Guided Breast Cancer Surgery and Enhanced Radiotherapy Efficacy.
Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting.
Analysis and verification of the circRNA regulatory network RNO_CIRCpedia_ 4214/RNO-miR-667-5p/Msr1 axis as a potential ceRNA promoting macrophage M2-like polarization in spinal cord injury.
Ligation to Scavenging Strategy Enables On-Demand Termination of Targeted Protein Degradation.
Downregulation of AC092894.1 promotes oxaliplatin resistance in colorectal cancer via the USP3/AR/RASGRP3 axis.
Allograft inflammatory factor 1 is a potential diagnostic, immunological, and prognostic biomarker in pan-cancer.
Recognition of an Ala-rich C-degron by the E3 ligase Pirh2.
Enhanced E6AP-mediated ubiquitination of ENO1 via LINC00663 contributes to radiosensitivity of breast cancer by regulating mitochondrial homeostasis.
Rift Valley Fever Virus Nucleoprotein Triggers Autophagy to Dampen Antiviral Innate Immune Responses.
Strategy To Assess Zoonotic Potential Reveals Low Risk Posed by SARS-Related Coronaviruses from Bat and Pangolin.
Progesterone prevents HGSOC by promoting precancerous cell pyroptosis via inducing fibroblast paracrine.
PIMT is a novel and potent suppressor of endothelial activation.
Unusually severe muscular dystrophy upon in-frame deletion of the dystrophin rod domain and lack of compensation by membrane-localized utrophin.
Circular RNA hsa_circ_0007444 inhibits ovarian cancer progression through miR-23a-3p/DICER1 axis.
LCRMP-1 is required for spermatogenesis and stabilises spermatid F-actin organization via the PI3K-Akt pathway.
Non-canonical Small GTPase RBJ Promotes NSCLC Progression Through the Canonical MEK/ERK Signaling Pathway.
Electroacupuncture-Regulated miR-34a-3p/PDCD6 Axis Promotes Post-Spinal Cord Injury Recovery in Both In Vitro and In Vivo Settings.
Protective Effects of the Wenfei Buqi Tongluo Formula on the Inflammation in Idiopathic Pulmonary Fibrosis through Inhibiting the TLR4/MyD88/NF-κB Pathway.
ATF4/MYC Regulates MTHFD2 to Promote NSCLC Progression by Mediating Redox Homeostasis.
Alarm Signal S100-Related Signature Is Correlated with Tumor Microenvironment and Predicts Prognosis in Glioma.
Predicting the Immune Microenvironment and Prognosis with a NETosis-Related lncRNA Signature in Head and Neck Squamous Cell Carcinoma.
Water Treadmill Training Ameliorates Neurite Outgrowth Inhibition Associated with NGR/RhoA/ROCK by Inhibiting Astrocyte Activation following Spinal Cord Injury.
Corilagin Restrains NLRP3 Inflammasome Activation and Pyroptosis through the ROS/TXNIP/NLRP3 Pathway to Prevent Inflammation.
Suppressing MDSC Infiltration in Tumor Microenvironment Serves as an Option for Treating Ovarian Cancer Metastasis.
CIRBP-OGFR axis safeguards against cardiomyocyte apoptosis and cardiotoxicity induced by chemotherapy.
Melatonin reverses tumor necrosis factor-alpha-induced metabolic disturbance of human nucleus pulposus cells via MTNR1B/Gαi2/YAP signaling.
MAD2B promotes podocyte injury through regulating Numb-dependent Notch 1 pathway in diabetic nephropathy.
Identification of potential key circular RNAs related to cognitive impairment after chronic constriction injury of the sciatic nerve.
Antidepressant-Like Effect and Mechanism of Ginsenoside Rd on Rodent Models of Depression.
Laparotomy-Induced Peripheral Inflammation Activates NR2B Receptors on the Brain Mast Cells and Results in Neuroinflammation in a Vagus Nerve-Dependent Manner.
Carbon Monoxide-Releasing Molecule-3 Enhances Osteogenic Differentiation of Rat Bone Marrow Mesenchymal Stem Cells via miR-195-5p/Wnt3a Pathway.
The Therapeutic Effect and the Possible Mechanism of C-Phycocyanin in Lipopolysaccharide and Seawater-Induced Acute Lung Injury.
Nedd4-2 Haploinsufficiency in Mice Impairs the Ubiquitination of Rer1 and Increases the Susceptibility to Endoplasmic Reticulum Stress and Seizures.
FMNL3 is Overexpressed in Tumor Tissues and Predicts an Immuno-Hot Phenotype in Pancreatic Cancer.
The Pathogenic Mechanism of the ATP2C1 p.Ala109_Gln120del Mutation in Hailey-Hailey Disease.
DNA 6mA Demethylase ALKBH1 Orchestrates Fatty Acid Metabolism and Suppresses Diet-Induced Hepatic Steatosis.
Porphyromonas gingivalis lipopolysaccharide induced RIPK3/MLKL-mediated necroptosis of oral epithelial cells and the further regulation in macrophage activation.
Confinement induces oxidative damage and synaptic dysfunction in mice.
A pyroptosis-related gene model and its correlation with the microenvironment of lung adenocarcinoma: A bioinformatics analysis and experimental verification.
Critical role of guanylate binding protein 5 in tumor immune microenvironment and predictive value of immunotherapy response.
Honokiol improves depression-like behaviors in rats by HIF-1α- VEGF signaling pathway activation.
Shenkang injection improves chronic kidney disease by inhibiting multiple renin-angiotensin system genes by blocking the Wnt/β-catenin signalling pathway.
Inhibition of HDAC6 With CAY10603 Ameliorates Diabetic Kidney Disease by Suppressing NLRP3 Inflammasome.
Hypoxic Training Ameliorates Skeletal Muscle Microcirculation Vascular Function in a Sirt3-Dependent Manner.
Clostridium butyricum Protects Against Pancreatic and Intestinal Injury After Severe Acute Pancreatitis via Downregulation of MMP9.
Artemisinin relieves myocardial ischemia-reperfusion injury via modulating miR-29b-3p and hemicentin 1.
Connexin 43 (Cx43) regulates high-glucose-induced retinal endothelial cell angiogenesis and retinal neovascularization.
EspF of Enterohemorrhagic Escherichia coli Enhances Apoptosis via Endoplasmic Reticulum Stress in Intestinal Epithelial Cells: An Isobaric Tags for Relative and Absolute Quantitation-Based Comparative Proteomic Analysis.
Platelet-Vesicles-Encapsulated RSL-3 Enable Anti-Angiogenesis and Induce Ferroptosis to Inhibit Pancreatic Cancer Progress.
Theaflavin-3,3'-Digallate from Black Tea Inhibits Neointima Formation Through Suppression of the PDGFRβ Pathway in Vascular Smooth Muscle Cells.
Gentiopicroside Ameliorates Diabetic Renal Tubulointerstitial Fibrosis via Inhibiting the AT1R/CK2/NF-κB Pathway.
ING4 Promotes Stemness Enrichment of Human Renal Cell Carcinoma Cells Through Inhibiting DUSP4 Expression to Activate the p38 MAPK/type I IFN-Stimulated Gene Signaling Pathway.
Identification of a De Novo Heterozygous Missense ACTB Variant in Baraitser-Winter Cerebrofrontofacial Syndrome.
Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKα/β-NF-κB and Keap1-Nrf2 Signalling Pathways.
PKC-ζ Aggravates Doxorubicin-Induced Cardiotoxicity by Inhibiting Wnt/β-Catenin Signaling.
Chemerin Regulates the Proliferation and Migration of Pulmonary Arterial Smooth Muscle Cells via the ERK1/2 Signaling Pathway.
The Transcription of ZIP9 Is Associated With the Macrophage Polarization and the Pathogenesis of Hepatocellular Carcinoma.
Narciclasine inhibits phospholipase A2 and regulates phospholipid metabolism to ameliorate psoriasis-like dermatitis.
SIRT6 overexpression retards renal interstitial fibrosis through targeting HIPK2 in chronic kidney disease.
A novel HDAC11 inhibitor potentiates the tumoricidal effects of cordycepin against malignant peripheral nerve sheath tumor through the Hippo signaling pathway.
GPR12 Inhibits Apoptosis in Epithelial Ovarian Cancer via the Activation of ERK1/2 Signaling.
ESR1 Regulates the Obesity- and Metabolism-Differential Gene MMAA to Inhibit the Occurrence and Development of Hepatocellular Carcinoma.
Immune Characteristics and Prognosis Analysis of the Proteasome 20S Subunit Beta 9 in Lower-Grade Gliomas.
STAT6 Upregulates NRP1 Expression in Endothelial Cells and Promotes Angiogenesis.
DJ-1 promotes osteosarcoma progression through activating CDK4/RB/E2F1 signaling pathway.
Crosstalk between acetylation and the tyrosination/detyrosination cycle of α-tubulin in Alzheimer's disease.
Hyaluronic Acid Facilitates Angiogenesis of Endothelial Colony Forming Cell Combining With Mesenchymal Stem Cell via CD44/ MicroRNA-139-5p Pathway.
Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer.
Macrophage derived miR-7219-3p-containing exosomes mediate fibroblast trans-differentiation by targeting SPRY1 in silicosis.
PRSS55 is a novel potential causative gene for human male infertility.
Fatty acid-binding protein 5 aggravates pulmonary artery fibrosis in pulmonary hypertension secondary to left heart disease via activating wnt/β-catenin pathway.
Nuclear Condensation of CDYL Links Histone Crotonylation and Cystogenesis in Autosomal Dominant Polycystic Kidney Disease.
Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia.
Cullin 4b-RING ubiquitin ligase targets IRGM1 to regulate Wnt signaling and intestinal homeostasis.
PGM3 regulates beta-catenin activity to promote colorectal cancer cell progression.
Opposing reduced VPAC(1) and enhanced VPAC(2) VIP receptors in the hippocampus of the Li(2+)-pilocarpine rat model of temporal lobe epilepsy.
Generation of cost-effective MXene@polydopamine-decorated chitosan nanofibrous wound dressing for promoting wound healing.
Grass Carp Reovirus triggers autophagy enhancing virus replication via the Akt/mTOR pathway.
Improvement of anticancer effect of berberine by salt formation modifications.
Atractylenolide III from Atractylodes macrocephala Koidz promotes the activation of brown and white adipose tissue through SIRT1/PGC-1α signaling pathway.
Prinsepiae Nux Extract Activates NRF2 Activity and Protects UVB-Induced Damage in Keratinocyte.
Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.
Proteomic characterization of gastric cancer response to chemotherapy and targeted therapy reveals new therapeutic strategies.
HOXA5 inhibits the proliferation of extrahepatic cholangiocarcinoma cells by enhancing MXD1 expression and activating the p53 pathway.
PGC-1β maintains mitochondrial metabolism and restrains inflammatory gene expression.
miR-182-5p attenuates Schistosoma japonicum-induced hepatic fibrosis by targeting tristetraprolin.
Design, Synthesis, and Biological Evaluation of Androgen Receptor Degrading and Antagonizing Bifunctional Steroidal Analogs for the Treatment of Advanced Prostate Cancer.
Intestinal Epithelial STAT6 Activation Rescues the Defective Anti-Helminth Responses Caused by Ogt Deletion.
TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation.
Mechanism underlying the targeted regulation of the SOD1 3'UTR by the AUF1/Dicer1/miR-155/SOD1 pathway in sodium arsenite-induced liver injury.
Avermectin induces carp neurotoxicity by mediating blood-brain barrier dysfunction, oxidative stress, inflammation, and apoptosis through PI3K/Akt and NF-κB pathways.
HDAC6 Inhibition Alleviates Anesthesia and Surgery-Induced Less Medial Prefrontal-Dorsal Hippocampus Connectivity and Cognitive Impairment in Aged Rats.
Inka2, a novel Pak4 inhibitor, regulates actin dynamics in neuronal development.
LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway.
Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein.
p-hydroxy benzaldehyde revitalizes the microenvironment of peri-infarct cortex in rats after cerebral ischemia-reperfusion.
Involvement of Rab11 in osteoblastic differentiation: Its up-regulation during the differentiation and by tensile stress.
The Ion Channel Gene KCNAB2 Is Associated with Poor Prognosis and Loss of Immune Infiltration in Lung Adenocarcinoma.
Sinensetin attenuates IL-1β-induced cartilage damage and ameliorates osteoarthritis by regulating SERPINA3.
RBCK1 is an endogenous inhibitor for triple negative breast cancer via hippo/YAP axis.
Periodontal ligament fibroblasts-derived exosomes induced by PGE(2) inhibit human periodontal ligament stem cells osteogenic differentiation via activating miR-34c-5p/SATB2/ERK.
Angiotensin II induces podocyte metabolic reprogramming from glycolysis to glycerol-3-phosphate biosynthesis.
Activation of Piezo1 contributes to matrix stiffness-induced angiogenesis in hepatocellular carcinoma.
OTUB1 suppresses Hippo signaling via modulating YAP protein in gastric cancer.
High expression of aryl hydrocarbon receptor (AhR) plays an important role in the formation of fibrous epulis.
Therapeutic targeting of glutamate dehydrogenase 1 that links metabolic reprogramming and Snail-mediated epithelial-mesenchymal transition in drug-resistant lung cancer.
Par3 promotes breast cancer invasion and migration through pull tension and protein nanoparticle-induced osmotic pressure.
The m(6)A methyltransferase METTL3 promotes trophoblast cell invasion by regulating MYLK expression.
Capsaicin suppresses hepatocarcinogenesis by inhibiting the stemness of hepatic progenitor cells via SIRT1/SOX2 signaling pathway.
Identification of MYEOV-Associated Gene Network as a Potential Therapeutic Target in Pancreatic Cancer.
A High Hepatic Uptake of Conjugated Bile Acids Promotes Colorectal Cancer-Associated Liver Metastasis.
Bombesin receptor-activated protein exacerbates cisplatin-induced AKI by regulating the degradation of SIRT2.
Drebrin promotes lung adenocarcinoma cell migration through inducing integrin β1 endocytosis.
SOX4 Mediates ATRA-Induced Differentiation in Neuroblastoma Cells.
Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.
SYTL5 Promotes Papillary Thyroid Carcinoma Progression by Enhancing Activation of the NF-κB Signaling Pathway.
ATRA-mediated-crosstalk between stellate cells and Kupffer cells inhibits autophagy and promotes NLRP3 activation in acute liver injury.
LINC01431 Promotes Histone H4R3 Methylation to Impede HBV Covalently Closed Circular DNA Transcription by Stabilizing PRMT1.
FOXO acts as a positive regulator of CncC and deltamethrin tolerance in the red flour beetle, Tribolium castaneum.
The hypoxia-inducible factor prolyl hydroxylase inhibitor FG4592 promotes natriuresis through upregulation of COX2 in the renal medulla.
Allopregnanolone suppresses glioblastoma survival through decreasing DPYSL3 and S100A11 expression.
Hydrogen-Rich Medium Regulates Cr(VI)-Induced ER Stress and Autophagy Signaling in DF-1 Cells.
Inhibitory effect of aptamer-carbon dot nanomaterial-siRNA complex on the metastasis of hepatocellular carcinoma cells by interfering with FMRP.
Effect of nicotinamide N-methyltransferase on lipid accumulation in 3T3-L1 adipocytes.
Design and synthesis of Aza-boeravinone derivatives as potential novel topoisomerase I inhibitors.
IL-33 in the basolateral amygdala integrates neuroinflammation into anxiogenic circuits via modulating BDNF expression.
STRIPAK regulation of katanin microtubule severing in the Caenorhabditis elegans embryo.
Cholesterol determines the cytosolic entry and seeded aggregation of tau.
A novel isoform of hydroxyacyl-CoA dehydrogenase inhibits cell proliferation.
Quinoline alkaloids with anti-inflammatory activity from Zanthoxylum avicennae.
METTL3-mediated m(6)A RNA methylation regulates dorsal lingual epithelium homeostasis.
Nrf2 and NF-κB/NLRP3 inflammasome pathways are involved in Prototheca bovis infections of mouse mammary gland tissue and mammary epithelial cells.
Lytic cocktail: An effective method to alleviate severe burn induced hyper-metabolism through regulating white adipose tissue browning.
Estrogen-related Receptor α (ERRα) Functions in The Hypoxic Injury of Microglial Cells.
Lower expression of PDZRN3 induces endometrial carcinoma progression via the activation of canonical Wnt signaling.
The phytochemical, corynoline, diminishes Aurora kinase B activity to induce mitotic defect and polyploidy.
Inhibition of translocator protein 18 kDa suppressed the progression of glioma via the ELAV-like RNA-binding protein 1/MAPK-activated protein kinase 3 axis.
eEF2K promotes PD-L1 stabilization through inactivating GSK3β in melanoma.
Moderate heart rate reduction promotes cardiac regeneration through stimulation of the metabolic pattern switch.
Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer's disease.
Loss of NPPA-AS1 promotes heart regeneration by stabilizing SFPQ-NONO heteromer-induced DNA repair.
UPF1 contributes to the maintenance of endometrial cancer stem cell phenotype by stabilizing LINC00963.
lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma.
Nardilysin in adipocytes regulates UCP1 expression and body temperature homeostasis.
IGF-1 Signaling Regulates Mitochondrial Remodeling during Myogenic Differentiation.
Engineering Lipusu with lysophosphatidylcholine for improved tumor cellular uptake and anticancer efficacy.
Slit guidance ligand 2 promotes the inflammatory response of periodontitis through activation of the NF-κB signaling pathway.
The TLR-chaperone CNPY3 is a critical regulator of NLRP3-inflammasome activation.
FLT4/VEGFR3 activates AMPK to coordinate glycometabolic reprogramming with autophagy and inflammasome activation for bacterial elimination.
Blockade of TMEM16A protects against renal fibrosis by reducing intracellular Cl(-) concentration.
Brain aging is faithfully modelled in organotypic brain slices and accelerated by prions.
SUMO2-mediated SUMOylation of SH3GLB1 promotes ionizing radiation-induced hypertrophic cardiomyopathy through mitophagy activation.
Long noncoding RNA GAS5 attenuates cigarette smoke-induced airway remodeling by regulating miR-217-5p/PTEN axis.
The Expression and Role Analysis of Methylation-Regulated Differentially Expressed Gene UBE2C in Pan-Cancer, Especially for HGSOC.
ARIH2 regulates the proliferation, DNA damage and chemosensitivity of gastric cancer cells by reducing the stability of p21 via ubiquitination.
Mitochondrial FAD shortage in SLC25A32 deficiency affects folate-mediated one-carbon metabolism.
In vitro and in vivo assay of the ER lipid scramblase TMEM41B.
Silencing GOLGA8B inhibits cell invasion and metastasis by suppressing STAT3 signaling pathway in lung squamous cell carcinoma.
Perfluorooctane sulfonate induces mitochondrial calcium overload and early hepatic insulin resistance via autophagy/detyrosinated alpha-tubulin-regulated IP3R2-VDAC1-MICU1 interaction.
The hsa-miR-214-3p/ATGL axis regulates aberrant lipolysis to promote acute myeloid leukemia progression via PPARα in vitro.
Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death.
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer.
TET2-BCLAF1 transcription repression complex epigenetically regulates the expression of colorectal cancer gene Ascl2 via methylation of its promoter.
Iron-regulated assembly of the cytosolic iron-sulfur cluster biogenesis machinery.
Ciliary transition zone proteins coordinate ciliary protein composition and ectosome shedding.
TRIM25 inhibits influenza A virus infection, destabilizes viral mRNA, but is redundant for activating the RIG-I pathway.
Box C/D snoRNA SNORD89 influences the occurrence and development of endometrial cancer through 2'-O-methylation modification of Bim.
Peptide PDHPS1 Inhibits Ovarian Cancer Growth through Disrupting YAP Signaling.
Impaired Bestrophin Channel Activity in an iPSC-RPE Model of Best Vitelliform Macular Dystrophy (BVMD) from an Early Onset Patient Carrying the P77S Dominant Mutation.
White tea alleviates non-alcoholic fatty liver disease by regulating energy expenditure and lipid metabolism.
Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy.
Effects of Artemisinin on Escherichia coli-Induced Mastitis in Bovine Mammary Epithelial Cells and Mice.
Mitochondria-Targeting Polymer Micelle of Dichloroacetate Induced Pyroptosis to Enhance Osteosarcoma Immunotherapy.
C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.
Effect of Houpo-Mahuang Decoction on aggravated asthma induced by cigarette smoke and the expression of TRPA1 and tight junctions in mice.
Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.
ZEB2/TWIST1/PRMT5/NuRD Multicomplex Contributes to the Epigenetic Regulation of EMT and Metastasis in Colorectal Carcinoma.
Fine-Tuning of Cholesterol Homeostasis Controls Erythroid Differentiation.
Caveolin-1 negatively regulates inflammation and fibrosis in silicosis.
Butyrate ameliorates skeletal muscle atrophy in diabetic nephropathy by enhancing gut barrier function and FFA2-mediated PI3K/Akt/mTOR signals.
Virus-induced FoxO factor facilitates replication of human cytomegalovirus.
MACF1 promotes osteoblastic cell migration by regulating MAP1B through the GSK3beta/TCF7 pathway.
Dihydroartemisinin enhances the inhibitory effect of sorafenib on HepG2 cells by inducing ferroptosis and inhibiting energy metabolism.
Overexpression of sFlt-1 represses ox-LDL-induced injury of HUVECs by activating autophagy via PI3K/AKT/mTOR pathway.
High expression of small nucleolar RNA host gene 3 predicts poor prognosis and promotes bone metastasis in prostate cancer by activating transforming growth factor-beta signaling.
αTAT1-induced tubulin acetylation promotes ameloblastoma migration and invasion.
Curcumin reduces oxidative stress and fat deposition in longissimus dorsi muscle of intrauterine growth-retarded finishing pigs.
Bifidobacterium spp. and their metabolite lactate protect against acute pancreatitis via inhibition of pancreatic and systemic inflammatory responses.
Oncogenic role of the SOX9-DHCR24-cholesterol biosynthesis axis in IGH-BCL2+ diffuse large B-cell lymphomas.
SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease.
m6A modifications regulate intestinal immunity and rotavirus infection.
The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB.
The Role of Sirtuin 1 in Palmitic Acid-Induced Endoplasmic Reticulum Stress in Cardiac Myoblasts.
Regulation of TET2 gene expression and 5mC oxidation in breast cancer cells by estrogen signaling.
ZC3H15 promotes gastric cancer progression by targeting the FBXW7/c-Myc pathway.
PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40.
The Ancient and Evolved Mouse Sperm-Associated Antigen 6 Genes Have Different Biologic Functions In Vivo.
KCTD10 regulates brown adipose tissue thermogenesis and metabolic function via Notch signaling.
ZC3H15 promotes glioblastoma progression through regulating EGFR stability.
Aging is associated with increased brain iron through cortex-derived hepcidin expression.
Bombyx mori Akirin hijacks a viral peptide vSP27 encoded by BmCPV circRNA and activates the ROS-NF-κB pathway against viral infection.
Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress via modulation of Keap1/Nrf2 signaling pathway.
Alkbh1-mediated DNA N6-methyladenine modification regulates bone marrow mesenchymal stem cell fate during skeletal aging.
LncRNA Riken Attenuated Sevoflurane-Induced Neuroinflammation by Regulating the MicroRNA-101a/MKP-1/JNK Pathway.
RNF6 promotes the migration and invasion of breast cancer by promoting the ubiquitination and degradation of MST1.
Polarity protein Par3 sensitizes breast cancer to paclitaxel by promoting cell cycle arrest.
The phosphatase of regenerating liver-3 protein (PRL-3) promotes glioma cell invasiveness by interacting with β3 -tubulin.
Effect of resistance training on satellite cells in old mice - a transcriptome study : implications for sarcopenia.
Metabolic Reprogramming in Response to Alterations of Mitochondrial DNA and Mitochondrial Dysfunction in Gastric Adenocarcinoma.
HDAC9 Contributes to Serous Ovarian Cancer Progression through Regulating Epithelial-Mesenchymal Transition.
Targeting polarized phenotype of microglia via IL6/JAK2/STAT3 signaling to reduce NSCLC brain metastasis.
Cucurbitacin E inhibits cellular proliferation and induces apoptosis in melanoma by suppressing HSDL2 expression.
Impaired KDM2B-mediated PRC1 recruitment to chromatin causes defective neural stem cell self-renewal and ASD/ID-like behaviors.
PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease.
Hypoxic training upregulates mitochondrial turnover and angiogenesis of skeletal muscle in mice.
MRCK-Alpha and Its Effector Myosin II Regulatory Light Chain Bind ABCB4 and Regulate Its Membrane Expression.
N(6) -Methyladenosine-Modified CBX1 Regulates Nasopharyngeal Carcinoma Progression Through Heterochromatin Formation and STAT1 Activation.
TERC suppresses PD-L1 expression by downregulating RNA binding protein HuR.
Qiangli Wuhu mixture alleviates LPS-induced pneumonia by inhibiting the TLR4/NF-κB/NLRP3 pathway: a study based on network pharmacology.
Myostain is involved in ginsenoside Rb1-mediated anti-obesity.
Low STING expression promotes endometrial stromal cell invasion and migration via the STING/IRF-3/IFN-β1 pathway in eutopic endometrium of women with endometriosis.
Human cytomegalovirus UL24 and UL43 products participate in SAMHD1 subcellular localization.
The interaction between E3 ubiquitin ligase Parkin and mitophagy receptor PHB2 links inner mitochondrial membrane ubiquitination to efficient mitophagy.
CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer's disease.
IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas.
In Vitro Inhibitory Effects of Maqian Essential Oil against Ectopic Endometrial Stromal Cells and LPS-Induced Endometrial Epithelial Cells.
Tumor-targeted dual-starvation therapy based on redox-responsive micelle nanosystem with co-loaded LND and BPTES.
The transcription factor KLF14 attenuates LPS-induced acute lung injury by ameliorating apoptosis of alveolar epithelial cells in mice.
Gut dysbacteriosis attenuates resistance to Mycobacterium bovis infection by decreasing cyclooxygenase 2 to inhibit endoplasmic reticulum stress.
Circ-CREBBP inhibits sperm apoptosis via the PI3K-Akt signaling pathway by sponging miR-10384 and miR-143-3p.
HDAC6 Inhibition Alleviates Ischemia- and Cisplatin-Induced Acute Kidney Injury by Promoting Autophagy.
The central scaffold protein CEP350 coordinates centriole length, stability, and maturation.
Wnt/β-Catenin Signaling Inhibits Osteogenic Differentiation in Human Periodontal Ligament Fibroblasts.
RNF31 represses cell progression and immune evasion via YAP/PD-L1 suppression in triple negative breast Cancer.
C/D box small nucleolar RNA SNORD104 promotes endometrial cancer by regulating the 2'-O-methylation of PARP1.
WNT6 participates in the occurrence and development of ovarian cancer by upregulating/activating the typical Wnt pathway and Notch1 signaling pathway.
De novo non-synonymous DPYSL2 (CRMP2) variants in two patients with intellectual disabilities and documentation of functional relevance through zebrafish rescue and cellular transfection experiments.
The Photoperiod Regulates Granulosa Cell Apoptosis through the FSH-Nodal/ALK7 Signaling Pathway in Phodopus sungorus.
Oxidative stress modulates expression of immune checkpoint genes via activation of AhR signaling.
Anti-tumor effects and mechanism of a novel camptothecin derivative YCJ100.
miR21 modulates the Hippo signaling pathway via interference with PP2A Bβ to inhibit trophoblast invasion and cause preeclampsia.
TOPK Activation Exerts Protective Effects on Cisplatin-induced Acute Kidney Injury.
N(6)-methyladenosine (m(6)A) in 18S rRNA promotes fatty acid metabolism and oncogenic transformation.
Knockdown of bone morphogenetic protein 4 gene induces apoptosis and inhibits proliferation of bovine cumulus cells.
GPR108 is required for gambogic acid inhibiting NF-κB signaling in cancer.
PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression.
Targeting HECTD3-IKKα axis inhibits inflammation-related metastasis.
mTORC1 Mediates the Processes of Lysine Regulating Satellite Cells Proliferation, Apoptosis, and Autophagy.
Forsythiaside A Improves the Inhibitory Efficiency of Recombinant Protein Vaccines against Bovine Viral Diarrhea Virus Infection.
A mechanosensitive lipolytic factor in the bone marrow promotes osteogenesis and lymphopoiesis.
Anionic nanoplastic exposure induces endothelial leakiness.
cAMP-Induced Nuclear Condensation of CRTC2 Promotes Transcription Elongation and Cystogenesis in Autosomal Dominant Polycystic Kidney Disease.
Successful outcomes of intracytoplasmic sperm injection-embryo transfer using ejaculated spermatozoa from two Chinese asthenoteratozoospermic brothers with a compound heterozygous FSIP2 mutation.
Aurora kinase blockade drives de novo addiction of cervical squamous cell carcinoma to druggable EGFR signalling.
Time-dependent expression of ryanodine receptors in sea urchin eggs, zygotes and early embryos.
Silencing integrin α6 enhances the pluripotency-differentiation transition in human dental pulp stem cells.
The Acetylation Modification of SP1 Regulates the Protein Stability in Silkworm.
The transcription factor KLF14 regulates macrophage glycolysis and immune function by inhibiting HK2 in sepsis.
Morusin enhances the antitumor activity of MAPK pathway inhibitors in BRAF-mutant melanoma by inhibiting the feedback activation of STAT3.
HECTD3 promotes gastric cancer progression by mediating the polyubiquitination of c-MYC.
The m6A demethylase ALKBH5 promotes tumor progression by inhibiting RIG-I expression and interferon alpha production through the IKKε/TBK1/IRF3 pathway in head and neck squamous cell carcinoma.
Aldehyde dehydrogenase 2 and PARP1 interaction modulates hepatic HDL biogenesis by LXRα-mediated ABCA1 expression.
SFN Enhanced the Radiosensitivity of Cervical Cancer Cells via Activating LATS2 and Blocking Rad51/MDC1 Recruitment to DNA Damage Site.
Fumarate inhibits PTEN to promote tumorigenesis and therapeutic resistance of type2 papillary renal cell carcinoma.
Matrine injection inhibits pancreatic cancer growth via modulating carbonic anhydrases- a network pharmacology-based study with in vitro validation.
M1 Macrophages Enhance Survival and Invasion of Oral Squamous Cell Carcinoma by Inducing GDF15-Mediated ErbB2 Phosphorylation.
Tubastatin A Improves Post-Resuscitation Myocardial Dysfunction by Inhibiting NLRP3-Mediated Pyroptosis Through Enhancing Transcription Factor EB Signaling.
Reversal of Lipid Metabolism Dysregulation by Selenium and Folic Acid Co-Supplementation to Mitigate Pathology in Alzheimer's Disease.
Targeting DRD2 by the antipsychotic drug, penfluridol, retards growth of renal cell carcinoma via inducing stemness inhibition and autophagy-mediated apoptosis.
Two distinct males absent on the first (MOF)-containing histone acetyltransferases are involved in the epithelial-mesenchymal transition in different ways in human cells.
Aberrant expression of PROS1 correlates with human papillary thyroid cancer progression.
High PHD Finger Protein 19 (PHF19) expression predicts poor prognosis in colorectal cancer: a retrospective study.
Screening and identification of endometrial proteins as novel potential biomarkers for repeated implantation failure.
MicroRNA-222 Transferred From Semen Extracellular Vesicles Inhibits Sperm Apoptosis by Targeting BCL2L11.
Macrophage-Mediated Bone Formation in Scaffolds Modified With MSC-Derived Extracellular Matrix Is Dependent on the Migration Inhibitory Factor Signaling Pathway.
Cardioprotective Role of SIRT5 in Response to Acute Ischemia Through a Novel Liver-Cardiac Crosstalk Mechanism.
Urea as a By-Product of Ammonia Metabolism Can Be a Potential Serum Biomarker of Hepatocellular Carcinoma.
RBM14 Modulates Tubulin Acetylation and Regulates Spindle Morphology During Meiotic Maturation in Mouse Oocytes.
Impaired Retrograde Transport Due to Lack of TBC1D5 Contributes to the Trafficking Defect of Lysosomal Cathepsins in Ischemic/Hypoxic Cardiomyocytes.
S-Propargyl-Cysteine Attenuates Diabetic Cardiomyopathy in db/db Mice Through Activation of Cardiac Insulin Receptor Signaling.
Cold-Induced RNA-Binding Protein Promotes Glucose Metabolism and Reduces Apoptosis by Increasing AKT Phosphorylation in Mouse Skeletal Muscle Under Acute Cold Exposure.
Secreted Frizzled-Related Protein 5 Protects Against Cardiac Rupture and Improves Cardiac Function Through Inhibiting Mitochondrial Dysfunction.
Network-Based Expression Analyses and Experimental Verifications Reveal the Involvement of STUB1 in Acute Kidney Injury.
TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer.
Anticancer Action of Xiaoxianxiong Tang in Non-Small Cell Lung Cancer by Pharmacological Analysis and Experimental Validation.
ZC3H15 Correlates with a Poor Prognosis and Tumor Progression in Melanoma.
Brusatol Inhibits Tumor Growth and Increases the Efficacy of Cabergoline against Pituitary Adenomas.
Glucagon-like Peptide-1 Improves Fatty Liver and Enhances Thermogenesis in Brown Adipose Tissue via Inhibiting BMP4-Related Signaling Pathway in High-Fat-Diet-Induced Obese Mice.
USP1 Promotes GC Metastasis via Stabilizing ID2.
Folic Acid Protects Melanocytes from Oxidative Stress via Activation of Nrf2 and Inhibition of HMGB1.
Generation of VEGF knock-in Cashmere goat via the CRISPR/Cas9 system.
MAD2B-mediated cell cycle reentry of podocytes is involved in the pathogenesis of FSGS.
A Novel Hydrogen Sulfide Donor Reduces Pilocarpine-Induced Status Epilepticus and Regulates Microglial Inflammatory Profile.
Bardoxolone-Methyl Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in vitro and Alleviates Osteoarthritis in vivo.
A-FABP-PTEN/AKT Regulates Insulin Resistance in Preadipocyte Cell 3T3-L1 Cells.
Irradiation-Induced Activated Microglia Affect Brain Metastatic Colonization of NSCLC Cells via miR-9/CDH1 Axis.
STAT5 inhibitor attenuates atherosclerosis via inhibition of inflammation: the role of STAT5 in atherosclerosis.
Sevoflurane prevents pulmonary vascular remodeling and right ventricular dysfunction in pulmonary arterial hypertension in rats.
Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.
PFKP Activation Ameliorates Foot Process Fusion in Podocytes in Diabetic Kidney Disease.
Screening of a Small Molecule Compound Library Identifies Toosendanin as an Inhibitor Against Bunyavirus and SARS-CoV-2.
Pharmacological Inhibition of HMGB1 Prevents Muscle Wasting.
DMRT2 Interacts With FXR and Improves Insulin Resistance in Adipocytes and a Mouse Model.
Exploring the Prognostic Value, Immune Implication and Biological Function of H2AFY Gene in Hepatocellular Carcinoma.
Identification of a Novel Epigenetic Signature CHFR as a Potential Prognostic Gene Involved in Metastatic Clear Cell Renal Cell Carcinoma.
Effect of Xanthium Strumarium on HIV-1 5'-LTR Transcriptional Activity and Viral Reactivation in Latently Infected Cells.
Activation of STING Pathway Contributed to Cisplatin-Induced Cardiac Dysfunction via Promoting the Activation of TNF-α-AP-1 Signal Pathway.
Comprehensive Bioinformatics Analysis Identifies POLR2I as a Key Gene in the Pathogenesis of Hypertensive Nephropathy.
IL20RA signaling enhances stemness and promotes the formation of an immunosuppressive microenvironment in breast cancer.
Glycosylation of Siglec15 promotes immunoescape and tumor growth.
Cordycepin inhibits the proliferation of malignant peripheral nerve sheath tumor cells through the p53/Sp1/tubulin pathway.
Pan-Cancer Analyses Reveal Oncogenic Role and Prognostic Value of F-Box Only Protein 22.
Modulated TRPC1 Expression Predicts Sensitivity of Breast Cancer to Doxorubicin and Magnetic Field Therapy: Segue Towards a Precision Medicine Approach.
Potential Role of SWI/SNF Complex Subunit Actin-Like Protein 6A in Cervical Cancer.
Periodontal Pathogens Promote Oral Squamous Cell Carcinoma by Regulating ATR and NLRP3 Inflammasome.
Oleic Acid and Insulin as Key Characteristics of T2D Promote Colorectal Cancer Deterioration in Xenograft Mice Revealed by Functional Metabolomics.
PGK1 Is a Key Target for Anti-Glycolytic Therapy of Ovarian Cancer: Based on the Comprehensive Analysis of Glycolysis-Related Genes.
Identification METTL18 as a Potential Prognosis Biomarker and Associated With Immune Infiltrates in Hepatocellular Carcinoma.
Targeting Mutated p53 Dependency in Triple-Negative Breast Cancer Cells Through CDK7 Inhibition.
Dihydrocapsaicin Inhibits Cell Proliferation and Metastasis in Melanoma via Down-regulating β-Catenin Pathway.
Salmonella Effector SpvB Inhibits NF-κB Activity via KEAP1-Mediated Downregulation of IKKβ.
Loss of TARBP2 Drives the Progression of Hepatocellular Carcinoma via miR-145-SERPINE1 Axis.
Pterostilbene and its nicotinate derivative ameliorated vascular endothelial senescence and elicited endothelium-dependent relaxations via activation of sirtuin 1.
Inhibitory effect of HTLV-1 infection on the production of B-cell activating factors in established follicular dendritic cell-like cells.
Lower levels of tubulin alpha 1b in the frontal pole in schizophrenia supports a role for changed cytoskeletal dynamics in the aetiology of the disorder.
SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination.
The inhibitory effect of the deubiquitinase cylindromatosis (CYLD) on inflammatory responses in human gingival fibroblasts.
Demethylzeylasteral inhibits proliferation, migration, and invasion through FBXW7/c-Myc axis in gastric cancer.
[ANXA8 Regulates Proliferation of Human Non-Small Lung Cancer Cells A549 via EGFR-AKT-mTOR Signaling Pathway].
CDC20 promotes bone formation via APC/C dependent ubiquitination and degradation of p65.
PEX5 prevents cardiomyocyte hypertrophy via suppressing the redox-sensitive signaling pathways MAPKs and STAT3.
Silencing ZIC2 abrogates tumorigenesis and anoikis resistance of non-small cell lung cancer cells by inhibiting Src/FAK signaling.
Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome.
The protective effect of isoflurane pretreatment on liver IRI by suppressing noncanonical pyroptosis of liver macrophages.
Effects of andrographolide on renal tubulointersticial injury and fibrosis. Evidence of its mechanism of action.
Assembly of Cytoplasmic Stress Granules in Placentas in Women with Preeclampsia.
Oxidized phospholipids on alkyl-amide scaffold demonstrate anti-endotoxin and endothelial barrier-protective properties.
Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases.
Deacetylation of BmAda3 is required for cell apoptosis caused by Bombyx mori nucleopolyhedrovirus infection.
Vitellogenin 2 promotes muscle development and stimulates the browning of white fat.
Design, Synthesis, and Biological Evaluation of Icaritin Derivatives as Novel Putative DEPTOR Inhibitors for Multiple Myeloma Treatment.
Folic Acid-Appended Hydroxypropyl-β-Cyclodextrin Exhibits Potent Antitumor Activity in Chronic Myeloid Leukemia Cells via Autophagic Cell Death.
19-Hydroxybufalin inhibits non-small cell lung cancer cell proliferation and promotes cell apoptosis via the Wnt/β-catenin pathway.
CHD8 safeguards early neuroectoderm differentiation in human ESCs and protects from apoptosis during neurogenesis.
Stem Cell Factor SOX2 Confers Ferroptosis Resistance in Lung Cancer via Upregulation of SLC7A11.
Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer.
Bortezomib potentiates antitumor activity of mitoxantrone through dampening Wnt/β-catenin signal pathway in prostate cancer cells.
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
ZFC3H1 prevents RNA trafficking into nuclear speckles through condensation.
Effects and Mechanisms of Synaptotagmin-7 in the Hippocampus on Cognitive Impairment in Aging Mice.
A novel CCDC39 mutation causes multiple morphological abnormalities of the flagella in a primary ciliary dyskinesia patient.
C23 gene regulates the nucleolin structure and biosynthesis of ribosomes in bovine intraspecific and interspecific somatic cell nuclear transfer embryos.
Inhibition of MAD2B alleviates venous neointimal formation by suppressing VSMCs proliferation and migration.
Perfluorooctane sulfonate induces autophagy-dependent lysosomal membrane permeabilization by weakened interaction between tyrosinated alpha-tubulin and spinster 1.
WIPI-1 inhibits metastasis and tumour growth via the WIPI-1-TRIM21 axis and MYC regulation in nasopharyngeal carcinoma.
Yeast Two-Hybrid Screen Identifies PKA-Riα Interacting Proteins during Mouse Spermiogenesis.
Cilia locally synthesize proteins to sustain their ultrastructure and functions.
Sesquiterpene Lactones from Sigesbeckia glabrescens Possessing Potent Anti-inflammatory Activity by Directly Binding to IKKα/β.
Programmed cell death 5 improves skeletal muscle insulin resistance by inhibiting IRS-1 ubiquitination through stabilization of MDM2.
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.
Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation.
The deubiquitinating enzyme ATXN3 promotes the progression of anaplastic thyroid carcinoma by stabilizing EIF5A2.
TMEM98, a novel secretory protein, promotes endothelial cell adhesion as well as vascular smooth muscle cell proliferation and migration.
W2476 represses TXNIP transcription via dephosphorylation of FOXO1 at Ser319.
Heme supplementation ameliorates lupus nephritis through rectifying the disorder of splenocytes and alleviating renal inflammation and oxidative damage.
Trojan Horse Delivery of 4,4'-Dimethoxychalcone for Parkinsonian Neuroprotection.
UFL1 regulates milk protein and fat synthesis-related gene expression of bovine mammary epithelial cells probably via the mTOR signaling pathway.
Role of epigenetic m(6) A RNA methylation in vascular development: mettl3 regulates vascular development through PHLPP2/mTOR-AKT signaling.
33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways.
Nicotine-derived NNK induces the stemness enrichment of CRC cells through regulating the balance of DUSP4-ERK1/2 feedback loop.
mTOR regulates PRMT1 expression and mitochondrial mass through STAT1 phosphorylation in hepatic cell.
Ubash3b promotes TPA-mediated suppression of leukemogenesis through accelerated downregulation of PKCδ protein.
Aging-associated lncRNAs are evolutionarily conserved and participate in NFκB signaling.
Pathogenesis of acephalic spermatozoa syndrome caused by SUN5 variant.
Ggps1 deficiency in the uterus results in dystocia by disrupting uterine contraction.
Pragmatic recruitment of memantine as the capping group for the design of HDAC inhibitors: A preliminary attempt to unravel the enigma of glioblastoma.
Model-based analysis uncovers mutations altering autophagy selectivity in human cancer.
Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus.
Genistein suppresses allergic contact dermatitis through regulating the MAP2K2/ERK pathway.
HSP90-dependent PUS7 overexpression facilitates the metastasis of colorectal cancer cells by regulating LASP1 abundance.
H(+)/Cl(‑) exchange transporter 7 promotes lysosomal acidification‑mediated autophagy in mouse cardiomyocytes.
Butyrate alleviates PTZ-induced mitochondrial dysfunction, oxidative stress and neuron apoptosis in mice via Keap1/Nrf2/HO-1 pathway.
Ganglioside GD3 regulates dendritic growth in newborn neurons in adult mouse hippocampus via modulation of mitochondrial dynamics.
AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation.
USP34 regulates tooth root morphogenesis by stabilizing NFIC.
Endometrial cell-derived small extracellular vesicle miR-100-5p promotes functions of trophoblast during embryo implantation.
Hepatic HuR protects against the pathogenesis of non-alcoholic fatty liver disease by targeting PTEN.
HN1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by interacting with STMN1.
SIRT1 inhibitors mitigate radiation-induced GI syndrome by enhancing intestinal-stem-cell survival.
Selenite Inhibits Notch Signaling in Cells and Mice.
The effects of myeloablative or non-myeloablative total body irradiations on intestinal tract in mice.
The antitumor role of a newly discovered α-d-glucan from Holotrichia diomphalia Bates as a selective blocker of aldolase A.
Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Exacerbates Podocyte Injury and the Progression of Diabetic Kidney Disease.
Tanshinone IIA prevents LPS-induced inflammatory responses in mice via inactivation of succinate dehydrogenase in macrophages.
Protective effects of total flavonoids from Qu Zhi Qiao (fruit of Citrus paradisi cv. Changshanhuyou) on OVA-induced allergic airway inflammation and remodeling through MAPKs and Smad2/3 signaling pathway.
T(reg) deficiency-mediated T(H) 1 response causes human premature ovarian insufficiency through apoptosis and steroidogenesis dysfunction of granulosa cells.
Immunoprecipitation Strategies to Isolate RIPK1/RIPK3 Complexes in Mouse Macrophages.
A human β-casein-derived peptide BCCY-1 modulates the innate immune response.
Dexmedetomidine post-conditioning attenuates cerebral ischemia following asphyxia cardiac arrest through down-regulation of apoptosis and neuroinflammation in rats.
DNA methylation mediated RSPO2 to promote follicular development in mammals.
RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.
Expression of Cntn1 is regulated by stress and associated with anxiety and depression phenotypes.
Engorgement of Rhipicephalus haemaphysaloides ticks blocked by silencing a protein inhibitor of apoptosis.
Apoptotic caspases suppress Mycobacterium bovis-induced IFN-β production in murine macrophage.
Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin.
Reconsolidation of a post-ingestive nutrient memory requires mTOR in the central amygdala.
Different roles of BAG3 in cardiac physiological hypertrophy and pathological remodeling.
Effects of cigarette smoke on the aggravation of ovalbumin-induced asthma and the expressions of TRPA1 and tight junctions in mice.
Enteric glial cells exert neuroprotection from hyperglycemia-induced damage via Akt/GSK3β pathway.
PKD2 deficiency suppresses amino acid biosynthesis in ADPKD by impairing the PERK-TBL2-eIF2ɑ-ATF4 pathway.
Planar cell polarity induces local microtubule bundling for coordinated ciliary beating.
Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress.
HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity.
Mitochondrial creatine kinase 1 in non-small cell lung cancer progression and hypoxia adaptation.
Actin-granule formation is an additional step in cardiac myofibroblast differentiation.
Esomeprazole overcomes paclitaxel-resistance and enhances anticancer effects of paclitaxel by inducing autophagy in A549/Taxol cells.
Mefunidone ameliorates diabetic kidney disease in STZ and db/db mice.
Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer.
The inhibition of colorectal cancer growth by the natural product macrocarpal I.
Characteristics of inflammation process in monocrotaline-induced pulmonary arterial hypertension in rats.
Neuroprotective effects of kukoamine A on 6-OHDA-induced Parkinson's model through apoptosis and iron accumulation inhibition.
Iron deficiency promotes aortic medial degeneration via destructing cytoskeleton of vascular smooth muscle cells.
Skip participates in formation and lipid metabolism of beige adipose and might mediate the effects of SIRT1 activator BTM-0512 on beige remodeling.
CSN6 promotes melanoma proliferation and metastasis by controlling the UBR5-mediated ubiquitination and degradation of CDK9.
Exosomes derived from thymic stromal lymphopoietin-treated dendritic cells regulate T helper 17/regulatory T cell differentiation via miR-21/Smad7 axis.
Changes in the expression of endothelial monocyte‑activating polypeptide II in the rat hippocampus following status epilepticus.
METTL3-Mediated m(6) A mRNA Methylation Modulates Tooth Root Formation by Affecting NFIC Translation.
Chlorpromazine, an antipsychotic agent, induces G2/M phase arrest and apoptosis via regulation of the PI3K/AKT/mTOR-mediated autophagy pathways in human oral cancer.
Targeting ROCK1/2 blocks cell division and induces mitotic catastrophe in hepatocellular carcinoma.
Knockdown of ASH1L methyltransferase induced apoptosis inhibiting proliferation and H3K36 methylation in bovine cumulus cells.
Vascular endothelial growth factor alleviates mitochondrial dysfunction and suppression of mitochondrial biogenesis in models of Alzheimer's disease.
Integrated analysis of microRNA and mRNA expression profiling identifies BAIAP3 as a novel target of dysregulated hsa-miR-1972 in age-related white matter lesions.
Central role of TRAP1 in the ameliorative effect of oleanolic acid on the mitochondrial-mediated and endoplasmic reticulum stress-excitated apoptosis induced by ochratoxin A.
Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing.
High glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy.
Aberrantly high activation of a FoxM1-STMN1 axis contributes to progression and tumorigenesis in FoxM1-driven cancers.
Semaphorin 3A promotes the osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells in inflammatory environments by suppressing the Wnt/β-catenin signaling pathway.
Histone Deacetylase Inhibitor SAHA Induces Expression of Fatty Acid-Binding Protein 4 and Inhibits Replication of Human Cytomegalovirus.
Small molecule targeting topoisomerase 3β for cancer therapy.
Keratin 19 maintains E-cadherin localization at the cell surface and stabilizes cell-cell adhesion of MCF7 cells.
Effects and mechanisms of probucol on aging-related hippocampus-dependent cognitive impairment.
Single-cell transcriptome atlas of human mesenchymal stem cells exploring cellular heterogeneity.
MiR-155-5p suppresses SOX1 to promote proliferation of cholangiocarcinoma via RAF/MEK/ERK pathway.
Initiation of oogenesis and meiosis in the fetal ovary depends on Dennd1a-mediated production of Wnt5a and retinoic acid from the somatic niches.
The RNA binding protein QKI5 suppresses ovarian cancer via downregulating transcriptional coactivator TAZ.
A circuit of COCH neurons encodes social-stress-induced anxiety via MTF1 activation of Cacna1h.
Loss-of-function missense variant of AKAP4 induced male infertility through reduced interaction with QRICH2 during sperm flagella development.
miR-378d suppresses malignant phenotype of ESCC cells through AKT signaling.
Drp1 SUMO/deSUMOylation by Senp5 isoforms influences ER tubulation and mitochondrial dynamics to regulate brain development.
Copper depletion modulates mitochondrial oxidative phosphorylation to impair triple negative breast cancer metastasis.
Prototheca spp. induce an inflammatory response via mtROS-mediated activation of NF-κB and NLRP3 inflammasome pathways in bovine mammary epithelial cell cultures.
GP73 is a TBC-domain Rab GTPase-activating protein contributing to the pathogenesis of non-alcoholic fatty liver disease without obesity.
ZNRF2 attenuates focal cerebral ischemia/reperfusion injury in rats by inhibiting mTORC1-mediated autophagy.
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target.
Aagab acts as a novel regulator of NEDD4-1-mediated Pten nuclear translocation to promote neurological recovery following hypoxic-ischemic brain damage.
K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle.
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.
AHR mediates the aflatoxin B1 toxicity associated with hepatocellular carcinoma.
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects.
WDR62 regulates spindle dynamics as an adaptor protein between TPX2/Aurora A and katanin.
Haploinsufficiency of the TDP43 ubiquitin E3 ligase RNF220 leads to ALS-like motor neuron defects in the mouse.
CBL aggravates Ang II-induced cardiac hypertrophy via the VHL/HIF-1α pathway.
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Adenosine A3 receptor activated in H(2)O(2) oxidative stress of primary open-angle glaucoma.
Triterpene saponins from Guo-gang-long attenuate collagen-induced arthritis via regulating A20 and inhibiting MAPK pathway.
Human splenic TER cells: A relevant prognostic factor acting via the artemin-GFRα3-ERK pathway in pancreatic ductal adenocarcinoma.
Dnajb8, a target gene of SOX30, is dispensable for male fertility in mice.
ASPH Regulates Osteogenic Differentiation and Cellular Senescence of BMSCs.
An MRTF-A-Sp1-PDE5 Axis Mediates Angiotensin-II-Induced Cardiomyocyte Hypertrophy.
Modulation of Increased mGluR1 Signaling by RGS8 Protects Purkinje Cells From Dendritic Reduction and Could Be a Common Mechanism in Diverse Forms of Spinocerebellar Ataxia.
PCDH7 Inhibits the Formation of Homotypic Cell-in-Cell Structure.
RGS12 is required for the maintenance of mitochondrial function during skeletal development.
Glutamine protects intestine against ischemia-reperfusion injury by alleviating endoplasmic reticulum stress induced apoptosis in rats.
Ambroxol Improves Neuronal Survival and Reduces White Matter Damage through Suppressing Endoplasmic Reticulum Stress in Microglia after Intracerebral Hemorrhage.
Mogroside V Protects against Hepatic Steatosis in Mice on a High-Fat Diet and LO2 Cells Treated with Free Fatty Acids via AMPK Activation.
MicroRNA-384 Inhibits the Progression of Papillary Thyroid Cancer by Targeting PRKACB.
Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis.
Wnt5a/CaMKII/ERK/CCL2 axis is required for tumor-associated macrophages to promote colorectal cancer progression.
MicroRNA-148a regulates low-density lipoprotein metabolism by repressing the (pro)renin receptor.
DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway.
Kaempferol attenuated cisplatin-induced cardiac injury via inhibiting STING/NF-κB-mediated inflammation.
EphA5 Silencing Increases the Radiosensitivity of ESCC Cells Through ATM-Dependent Pathway.
Hypoxia-induced MFAP5 Promotes Tumor Migration and Invasion via AKT Pathway in Head and Neck Squamous Cell Carcinoma.
Phosphoribosyl pyrophosphate synthetases 2 knockdown inhibits prostate cancer progression by suppressing cell cycle and inducing cell apoptosis.
Overexpression of KIAA0101 Promotes the Progression of Non-small Cell Lung Cancer.
Inward Tension of Talin and Integrin-related Osmotic Pressure are involved Synergetically in the Invasion and Metastasis of Non-small Cell Lung Cancer.
High-Intensity Interval Training Restores Glycolipid Metabolism and Mitochondrial Function in Skeletal Muscle of Mice With Type 2 Diabetes.
Coxsackievirus A6 Induces Necroptosis for Viral Production.
Establishment of cell lines with porcine spermatogonial stem cell properties.
Poricoic acid A as a modulator of TPH-1 expression inhibits renal fibrosis via modulating protein stability of β-catenin and β-catenin-mediated transcription.
SYTL4 downregulates microtubule stability and confers paclitaxel resistance in triple-negative breast cancer.
Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling.
Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
A Prognostic Prediction Model Developed Based on Four CpG Sites and Weighted Correlation Network Analysis Identified DNAJB1 as a Novel Biomarker for Pancreatic Cancer.
SYPL1 Inhibits Apoptosis in Pancreatic Ductal Adenocarcinoma via Suppression of ROS-Induced ERK Activation.
Caspase-3 inhibitor inhibits enterovirus D68 production.
The chromatin remodeler Brg1 is required for formation and maintenance of hematopoietic stem cells.
Therapeutic efficacy of antisense oligonucleotides in mouse models of CLN3 Batten disease.
Dependence of PINK1 accumulation on mitochondrial redox system.
Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway.
Comprehensive lipidomics in apoM(-/-) mice reveals an overall state of metabolic distress and attenuated hepatic lipid secretion into the circulation.
Metformin improves boar sperm quality via 5'-AMP-activated protein kinase-mediated energy metabolism in vitro.
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
Consumption of a Blueberry-Enriched Diet by Women for 6 Weeks Alters Determinants of Human Muscle Progenitor Cell Function.
Proline Protects Boar Sperm against Oxidative Stress through Proline Dehydrogenase-Mediated Metabolism and the Amine Structure of Pyrrolidine.
NQO1-selective activated prodrugs of combretastatin A-4: Synthesis and biological evaluation.
SARS-CoV-2 triggers inflammatory responses and cell death through caspase-8 activation.
Lycorine hydrochloride inhibits cell proliferation and induces apoptosis through promoting FBXW7-MCL1 axis in gastric cancer.
Broad-complex transcription factor mediates opposing hormonal regulation of two phylogenetically distant arginine kinase genes in Tribolium castaneum.
JARID1B promotes colorectal cancer proliferation and Wnt/β-catenin signaling via decreasing CDX2 level.
HOXA13 promotes colon cancer progression through β-catenin-dependent WNT pathway.
Platycodon grandifloras polysaccharides inhibit mitophagy injury induced by Cr (VI) in DF-1 cells.
Sulforaphane-cysteine inhibited migration and invasion via enhancing mitophagosome fusion to lysosome in human glioblastoma cells.
Anti-inflammatory and analgesic activities of indigo through regulating the IKKβ/IκB/NF-κB pathway in mice.
Atractyloside targets cancer-associated fibroblasts and inhibits the metastasis of colon cancer.
Arginase 1 is involved in lacrimal hyposecretion in male NOD mice, a model of Sjögren's syndrome, regardless of dacryoadenitis status.
Elevated miR-124-3p in the aging colon disrupts mucus barrier and increases susceptibility to colitis by targeting T-synthase.
Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity.
Melatonin Rescues the Ti Particle-Impaired Osteogenic Potential of Bone Marrow Mesenchymal Stem Cells via the SIRT1/SOD2 Signaling Pathway.
Oroxylin A alleviates immunoparalysis of CLP mice by degrading CHOP through interacting with FBXO15.
Acetylharpagide Protects Mice from Staphylococcus Aureus-Induced Acute Lung Injury by Inhibiting NF-κB Signaling Pathway.
Water treadmill training attenuates blood-spinal cord barrier disruption in rats by promoting angiogenesis and inhibiting matrix metalloproteinase-2/9 expression following spinal cord injury.
Cell Signaling Coordinates Global PRC2 Recruitment and Developmental Gene Expression in Murine Embryonic Stem Cells.
The RCAN1.4-calcineurin/NFAT signaling pathway is essential for hypoxic adaption of intervertebral discs.
DNA methylation‑regulated miR‑155‑5p depresses sensitivity of esophageal carcinoma cells to radiation and multiple chemotherapeutic drugs via suppression of MAP3K10.
Cognitive improvement and synaptic deficit attenuation by a multifunctional carbazole-based cyanine in AD mice model through regulation of Ca(2+)/CaMKII/CREB signaling pathway.
MKL1 mediates TGF-β-induced CTGF transcription to promote renal fibrosis.
Modulation of SIRT1-mediated signaling cascades in the liver contributes to the amelioration of nonalcoholic steatohepatitis in high fat fed middle-aged LDL receptor knockout mice by dihydromyricetin.
The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double-strand break repair.
Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.
GDF15 knockdown promotes erastin-induced ferroptosis by decreasing SLC7A11 expression.
Role of Clostridium perfringens Enterotoxin on YAP Activation in Colonic Sessile Serrated Adenoma/ Polyps with Dysplasia.
Second-order optimized regularized structured illumination microscopy (sorSIM) for high-quality and rapid super resolution image reconstruction with low signal level.
Autophagy suppression of trophoblast cells induces pregnancy loss by activating decidual NK cytotoxicity and inhibiting trophoblast invasion.
PIM1 inhibitor synergizes the anti-tumor effect of osimertinib via STAT3 dephosphorylation in EGFR-mutant non-small cell lung cancer.
Ophiopogonin D promotes bone regeneration by stimulating CD31(hi) EMCN(hi) vessel formation.
Elevated myocardial SORBS2 and the underlying implications in left ventricular noncompaction cardiomyopathy.
Inhibition of UCHL1 by LDN-57444 attenuates Ang II-Induced atrial fibrillation in mice.
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.
Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation.
AIM2 promotes the development of non-small cell lung cancer by modulating mitochondrial dynamics.
lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCF(β-TRCP)-Mediated Degradation of NRF2 in Pancreatic Cancer.
Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promotes colorectal cancer progression.
Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development.
MACF1 promotes preosteoblast migration by mediating focal adhesion turnover through EB1.
Dietary Supplemented Curcumin Improves Meat Quality and Antioxidant Status of Intrauterine Growth Retardation Growing Pigs via Nrf2 Signal Pathway.
PHLDA1 is a new therapeutic target of oxidative stress and ischemia reperfusion-induced myocardial injury.
Dlgap1 negatively regulates browning of white fat cells through effects on cell proliferation and apoptosis.
BRCA1 protects cardiac microvascular endothelial cells against irradiation by regulating p21-mediated cell cycle arrest.
AFF1 inhibits adipogenic differentiation via targeting TGM2 transcription.
Proanthocyanidins Promote Osteogenic Differentiation of Human Periodontal Ligament Fibroblasts in Inflammatory Environment Via Suppressing NF-κB Signal Pathway.
Transient inhibition of rDNA transcription in donor cells improves ribosome biogenesis and preimplantation development of embryos derived from somatic cell nuclear transfer.
Disregulation of Autophagy in the Transgenerational Cc2d1a Mouse Model of Autism.
Ophiocordyceps lanpingensis polysaccharides attenuate pulmonary fibrosis in mice.
Downregulated miR-150 in bone marrow mesenchymal stem cells attenuates the apoptosis of LPS-stimulated RAW264.7 via MTCH2-dependent mitochondria transfer.
Uncoupling DNA damage from chromatin damage to detoxify doxorubicin.
Ubiquitin C-terminal hydrolase L1 (UCHL1) regulates post-myocardial infarction cardiac fibrosis through glucose-regulated protein of 78 kDa (GRP78).
Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation.
Immune activation of murine RAW264.7 macrophages by sonicated and alkalized paramylon from Euglena gracilis.
Induction of ASC pyroptosis requires gasdermin D or caspase-1/11-dependent mediators and IFNβ from pyroptotic macrophages.
Fine particulate matter increases airway hyperresponsiveness through kallikrein-bradykinin pathway.
Modification of PLGA Scaffold by MSC-Derived Extracellular Matrix Combats Macrophage Inflammation to Initiate Bone Regeneration via TGF-β-Induced Protein.
Poricoic acid A activates AMPK to attenuate fibroblast activation and abnormal extracellular matrix remodelling in renal fibrosis.
Expression and significance of T-cell immunoglobulin mucin molecule 3 and its ligand galectin-9 in patients with adenomyosis.
EHF promotes colorectal carcinoma progression by activating TGF-β1 transcription and canonical TGF-β signaling.
Human alkaline ceramidase 2 promotes the growth, invasion, and migration of hepatocellular carcinoma cells via sphingomyelin phosphodiesterase acid-like 3B.
RNA-seq analysis of the key long noncoding RNAs and mRNAs related to cognitive impairment after cardiac arrest and cardiopulmonary resuscitation.
Clinically relevant high levels of human C-reactive protein induces endothelial dysfunction and hypertension by inhibiting the AMPK-eNOS axis.
RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins.
Downregulation of the circadian rhythm regulator HLF promotes multiple-organ distant metastases in non-small cell lung cancer through PPAR/NF-κb signaling.
Loss of ZC4H2 and RNF220 Inhibits Neural Stem Cell Proliferation and Promotes Neuronal Differentiation.
Design, synthesis and biological evaluation of homoerythrina alkaloid derivatives bearing a triazole moiety as PARP-1 inhibitors and as potential antitumor drugs.
Dichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway.
Sema7A, a brain immune regulator, regulates seizure activity in PTZ-kindled epileptic rats.
Poly (ADP-ribosylation) of HMGB1 facilitates its acetylation and promotes HMGB1 translocation-associated chemotherapy-induced autophagy in leukaemia cells.
Centrosome Amplification in Cancer Disrupts Autophagy and Sensitizes to Autophagy Inhibition.
Gentiopicroside activates the bile acid receptor Gpbar1 (TGR5) to repress NF-kappaB pathway and ameliorate diabetic nephropathy.
Knockdown of Rab9 Suppresses the Progression of Gastric Cancer Through Regulation of Akt Signaling Pathway.
MicroRNA-547-5p-mediated interleukin-33/suppressor of tumorigenicity 2 signaling underlies the genesis and maintenance of neuropathic pain and is targeted by the therapy with bone marrow stromal cells.
CXCL12/CXCR4 signaling induced itch and pain sensation in a murine model of allergic contact dermatitis.
5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl) imidazol (BZML) targets tubulin and DNA to induce anticancer activity and overcome multidrug resistance in colorectal cancer cells.
The Capsid Protein of Semliki Forest Virus Antagonizes RNA Interference in Mammalian Cells.
Inhibitory Activity of a Scorpion Defensin BmKDfsin3 against Hepatitis C Virus.
The nuclear translocation of transketolase inhibits the farnesoid receptor expression by promoting the binding of HDAC3 to FXR promoter in hepatocellular carcinoma cell lines.
RETRACTED: Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis.
ING4 alleviated lipopolysaccharide-induced inflammation by regulating the NF-κB pathway via a direct interaction with SIRT1.
Biallelic mutation of HSD17B4 induces middle age-onset spinocerebellar ataxia.
Functional analysis of natural PCSK9 mutants in modern and archaic humans.
Expanding the retinal phenotype of RP1: from retinitis pigmentosa to a novel and singular macular dystrophy.
The identification and characterisation of autophagy inhibitors from the published kinase inhibitor sets.
Hypermethylation of UCHL1 Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN).
Neurotoxicity and biomarkers of zinc oxide nanoparticles in main functional brain regions and dopaminergic neurons.
WDR62 is a novel participator in spindle migration and asymmetric cytokinesis during mouse oocyte meiotic maturation.
Bnip3 mediates doxorubicin-induced cardiomyocyte pyroptosis via caspase-3/GSDME.
Novel poricoic acids attenuate renal fibrosis through regulating redox signalling and aryl hydrocarbon receptor activation.
Asiaticoside Inhibits Neuronal Apoptosis and Promotes Functional Recovery After Spinal Cord Injury in Rats.
Aster-B coordinates with Arf1 to regulate mitochondrial cholesterol transport.
ZNF582 hypermethylation promotes metastasis of nasopharyngeal carcinoma by regulating the transcription of adhesion molecules Nectin-3 and NRXN3.
Synthesis and biological evaluation of (3/4-(pyrimidin-2-ylamino)benzoyl)-based hydrazine-1-carboxamide/carbothioamide derivatives as novel RXRα antagonists.
EBV-miR-BART12 accelerates migration and invasion in EBV-associated cancer cells by targeting tubulin polymerization-promoting protein 1.
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.
PhospholipaseCγ1/calcium-dependent membranous localization of Gsdmd-N drives endothelial pyroptosis, contributing to lipopolysaccharide-induced fatal outcome.
Macrophage-stimulating activity of European eel (Anguilla anguilla) peptides in RAW264.7 cells mediated via NF-κB and MAPK signaling pathways.
Naked antisense double-stranded DNA oligonucleotide efficiently suppresses BCR-ABL positive leukemic cells.
Corticosterone Induced the Increase of proBDNF in Primary Hippocampal Neurons Via Endoplasmic Reticulum Stress.
Mass spectrometry-based proteomic capture of proteins bound to the MACC1 promoter in colon cancer.
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
Super-enhancer-driven metabolic reprogramming promotes cystogenesis in autosomal dominant polycystic kidney disease.
Brain-Specific Serine-47 Modification of Cytochrome c Regulates Cytochrome c Oxidase Activity Attenuating ROS Production and Cell Death: Implications for Ischemia/Reperfusion Injury and Akt Signaling.
Mechanical Ring Interfaces between Adherens Junction and Contractile Actomyosin to Coordinate Entotic Cell-in-Cell Formation.
Regulation of Female Folliculogenesis by Tsp1a in Nile Tilapia (Oreochromis niloticus).
Plakoglobin is involved in cytoskeletal rearrangement of podocytes under the regulation of UCH-L1.
Pum2 mediates Sirt1 mRNA decay and exacerbates hypoxia/reoxygenation-induced cardiomyocyte apoptosis.
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
Sirtuin 2 Inhibition Attenuates Sevoflurane-Induced Learning and Memory Deficits in Developing Rats via Modulating Microglial Activation.
Antibiotic tigecycline inhibits cell proliferation, migration and invasion via down-regulating CCNE2 in pancreatic ductal adenocarcinoma.
C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis.
Alternatively Polarized Macrophages Regulate the Growth and Differentiation of Ependymal Stem Cells through the SIRT2 Pathway.
SIRT6-PARP1 is involved in HMGB1 polyADP-ribosylation and acetylation and promotes chemotherapy-induced autophagy in leukemia.
Hepatic CD147 knockout modulates liver steatosis and up-regulates autophagy in high-fat-diet-induced NAFLD mice.
Interleukin-17 suppresses grass carp reovirus infection in Ctenopharyngodon idellus kidney cells by activating NF-κB signaling.
Betulinic Acid-Mediated Tuning of PERK/CHOP Signaling by Sp1 Inhibition as a Novel Therapeutic Strategy for Glioblastoma.
Ovarian cancer cell-secreted exosomal miR-205 promotes metastasis by inducing angiogenesis.
Targeting JUN, CEBPB, and HDAC3: A Novel Strategy to Overcome Drug Resistance in Hypoxic Glioblastoma.
Identification of Aloperine as an anti-apoptotic Bcl2 protein inhibitor in glioma cells.
Cardiac proteomics reveals the potential mechanism of microtubule associated protein 4 phosphorylation-induced mitochondrial dysfunction.
Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence.
Myocardial Adipose Triglyceride Lipase Overexpression Protects against Burn-Induced Cardiac Lipid Accumulation and Injury.
Impaired Mitochondrial Fusion and Oxidative Phosphorylation Triggered by High Glucose Is Mediated by Tom22 in Endothelial Cells.
Cul4a as a New Interaction Protein of PARP1 Inhibits Oxidative Stress-Induced H9c2 Cell Apoptosis.
VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway.
Cancer-associated fibroblasts promote colorectal cancer progression by secreting CLEC3B.
SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.
Microtubule-associated protein 4 phosphorylation regulates epidermal keratinocyte migration and proliferation.
Histone Demethylase UTX is an Essential Factor for Zygotic Genome Activation and Regulates Zscan4 Expression in Mouse Embryos.
Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9.
Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells.
Osteoprotegerin promotes islet β cell proliferation in intrauterine growth retardation rats through the PI3K/AKT/FoxO1 pathway.
GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer.
Osteoglycin (OGN) Inhibits Cell Proliferation and Invasiveness in Breast Cancer via PI3K/Akt/mTOR Signaling Pathway.
Identification of the Potential Key Long Non-coding RNAs in Aged Mice With Postoperative Cognitive Dysfunction.
Dichloroacetate Overcomes Oxaliplatin Chemoresistance in Colorectal Cancer through the miR-543/PTEN/Akt/mTOR Pathway.
Qingpeng Ointment Ameliorates Inflammatory Responses and Dysregulation of Itch-Related Molecules for Its Antipruritic Effects in Experimental Allergic Contact Dermatitis.
DDX23, an Evolutionary Conserved dsRNA Sensor, Participates in Innate Antiviral Responses by Pairing With TRIF or MAVS.
Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum.
Functional role of GKAP1 in the regulation of male germ cell spontaneous apoptosis and sperm number.
miR-125b-5p targeting TRAF6 relieves skeletal muscle atrophy induced by fasting or denervation.
Calcium channel blockers reduce severe fever with thrombocytopenia syndrome virus (SFTSV) related fatality.
Interaction of hnRNP K with MAP 1B-LC1 promotes TGF-β1-mediated epithelial to mesenchymal transition in lung cancer cells.
Design, synthesis, antitumor activities and biological studies of novel diaryl substituted fused heterocycles as dual ligands targeting tubulin and katanin.
Proteomics Profiling of Host Cell Response via Protein Expression and Phosphorylation upon Dengue Virus Infection.
In situ repurposing of dendritic cells with CRISPR/Cas9-based nanomedicine to induce transplant tolerance.
TGF‑β induces periodontal ligament stem cell senescence through increase of ROS production.
Crosstalk between Cdk5/p35 and ERK1/2 signalling mediates spinal astrocyte activity via the PPARγ pathway in a rat model of chronic constriction injury.
CXCR7 regulates epileptic seizures by controlling the synaptic activity of hippocampal granule cells.
NEDD4 protects vascular endothelial cells against Angiotensin II-induced cell death via enhancement of XPO1-mediated nuclear export.
The LIV-1-GRPEL1 axis adjusts cell fate during anti-mitotic agent-damaged mitosis.
Endoplasmic reticulum stress, a novel significant mechanism responsible for DEHP-induced increased distance between seminiferous tubule of mouse testis.
Deficiency of PTEN leads to aberrant chromosome segregation through downregulation of MAD2.
MicroRNA-125a-3p affects smooth muscle cell function in vascular stenosis.
ASPP2 inhibits tumor growth by repressing the mevalonate pathway in hepatocellular carcinoma.
Bioinformatics Analysis Identifies Protein Tyrosine Kinase 7 (PTK7) as a Potential Prognostic and Therapeutic Biomarker in Stages I to IV Hepatocellular Carcinoma.
Mitochondrial pyruvate carrier 2 mediates mitochondrial dysfunction and apoptosis in high glucose-treated podocytes.
Enhancement of cortisol-induced SAA1 transcription by SAA1 in the human amnion.
Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial-lysosomal crosstalk.
Polypeptide N-acetylgalactosaminyltransferase 18 non-catalytically regulates the ER homeostasis and O-glycosylation.
Dorsomorphin induces cancer cell apoptosis and sensitizes cancer cells to HSP90 and proteasome inhibitors by reducing nuclear heat shock factor 1 levels.
Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.
PTK2 promotes cancer stem cell traits in hepatocellular carcinoma by activating Wnt/β-catenin signaling.
Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation.
Lamin A mutation impairs interaction with nucleoporin NUP155 and disrupts nucleocytoplasmic transport in atrial fibrillation.
NFAT1 Hypermethylation Promotes Epithelial-Mesenchymal Transition and Metastasis in Nasopharyngeal Carcinoma by Activating ITGA6 Transcription.
UNBS5162 inhibits SKOV3 ovarian cancer cell proliferation by regulating the PI3K/AKT signalling pathway.
CERKL regulates autophagy via the NAD-dependent deacetylase SIRT1.
The selective HDAC6 inhibitor Nexturastat A induces apoptosis, overcomes drug resistance and inhibits tumor growth in multiple myeloma.
Targeting the mDia Formin-Assembled Cytoskeleton Is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres.
An alternative membrane topology permits lipid droplet localization of peroxisomal fatty acyl-CoA reductase 1.
Accumulation of fructose 1,6-bisphosphate protects clear cell renal cell carcinoma from oxidative stress.
Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production.
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer.
Targeting Super-Enhancer-Driven Oncogenic Transcription by CDK7 Inhibition in Anaplastic Thyroid Carcinoma.
MiR-15b-5p is Involved in Doxorubicin-Induced Cardiotoxicity via Inhibiting Bmpr1a Signal in H9c2 Cardiomyocyte.
Antisense oligonucleotide treatment ameliorates IFN-γ-induced proteinuria in APOL1-transgenic mice.
The histone demethylase Kdm4 suppresses activation of hepatic stellate cell by inducing MiR-29 transcription.
Leonurine alleviates LPS-induced myocarditis through suppressing the NF-кB signaling pathway.
Esrrb plays important roles in maintaining self-renewal of trophoblast stem cells (TSCs) and reprogramming somatic cells to induced TSCs.
Dendrobium officinale polysaccharides regulate age-related lineage commitment between osteogenic and adipogenic differentiation.
Fine-Tuning of Shh/Gli Signaling Gradient by Non-proteolytic Ubiquitination during Neural Patterning.
HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration.
NPRL2 enhances autophagy and the resistance to Everolimus in castration-resistant prostate cancer.
Isosteviol Sodium Protects Neural Cells Against Hypoxia-Induced Apoptosis Through Inhibiting MAPK and NF-κB Pathways.
FOXO1 associated with sensitivity to chemotherapy drugs and glial-mesenchymal transition in glioma.
The pivotal role of protein acetylation in linking glucose and fatty acid metabolism to β-cell function.
HOXA9 is a novel myopia risk gene.
Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells.
Targeting of LRRC59 to the Endoplasmic Reticulum and the Inner Nuclear Membrane.
Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
An increase of estrogen receptor α protein level regulates BDE-209-mediated blood-testis barrier disruption during spermatogenesis in F1 mice.
CD147 promotes progression of head and neck squamous cell carcinoma via NF-kappa B signaling.
Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma.
AMPK Promotes SPOP-Mediated NANOG Degradation to Regulate Prostate Cancer Cell Stemness.
Helicobacter pylori induces intracellular galectin-8 aggregation around damaged lysosomes within gastric epithelial cells in a host O-glycan-dependent manner.
Palmitoylome profiling indicates that androgens regulate the palmitoylation of α‑tubulin in prostate cancer‑derived LNCaP cells and supernatants.
Cancer‑associated adipocytes exhibit distinct phenotypes and facilitate tumor progression in pancreatic cancer.
Adenosine Attenuates Aortic Smooth Muscle Cell Calcification through A(3) Adenosine Receptor.
Small GTPase Arf6 regulates diabetes-induced cholesterol accumulation in podocytes.
STRIP2 silencing inhibits vascular smooth muscle cell proliferation and migration via P38-AKT-MMP-2 signaling pathway.
Antitumor effects and mechanisms of 1,25(OH)2D3 in the Pfeiffer diffuse large B lymphoma cell line.
A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.
Membrane association but not identity is required for LRRK2 activation and phosphorylation of Rab GTPases.
Targeting CDK12-mediated transcription regulation in anaplastic thyroid carcinoma.
Involvement of STAT3 in the synergistic induction of 11β-HSD1 by SAA1 and cortisol in human amnion fibroblasts.
Extracellular RNAs-TLR3 signaling contributes to cognitive decline in a mouse model of postoperative cognitive dysfunction.
The Mechanism of Rap1 Regulates N-cadherin to Control Neuronal Migration.
Total flavonoids from sea buckthorn ameliorates lipopolysaccharide/cigarette smoke-induced airway inflammation.
Initial human T-cell leukemia virus type 1 infection of the salivary gland epithelial cells requires a biofilm-like structure.
E3 ligase Fbw7 participates in oxidative stress‑induced myocardial cell injury via interacting with Mcl‑1.
Inhibition of dendritic spine extension through acrolein conjugation with α-, β-tubulin proteins.
Mitochondrial NOS1 suppresses apoptosis in colon cancer cells through increasing SIRT3 activity.
Krüppel-like factor 3 inhibition by mutated lncRNA Reg1cp results in human high bone mass syndrome.
Large-conductance calcium-activated potassium channels mediate lipopolysaccharide-induced activation of murine microglia.
PAQR3 regulates phosphorylation of FoxO1 in insulin-resistant HepG2 cells via NF-κB signaling pathway.
Inhibition of glycogen catabolism induces intrinsic apoptosis and augments multikinase inhibitors in hepatocellular carcinoma cells.
The Novel Nature Microtubule Inhibitor Ivalin Induces G2/M Arrest and Apoptosis in Human Hepatocellular Carcinoma SMMC-7721 Cells In Vitro.
SHIP1 inhibits cell growth, migration, and invasion in non‑small cell lung cancer through the PI3K/AKT pathway.
Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation.
Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors.
Altered expression of p63 isoforms and expansion of p63- and club cell secretory protein-positive epithelial cells in the lung as novel features of aging.
Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.
Caspase-3 Inhibition Attenuates the Cytopathic Effects of EV71 Infection.
The Protective Effect of Astaxanthin on Cognitive Function via Inhibition of Oxidative Stress and Inflammation in the Brains of Chronic T2DM Rats.
Fas Signaling in Dendritic Cells Mediates Th2 Polarization in HDM-Induced Allergic Pulmonary Inflammation.
TRIM31 Deficiency Is Associated with Impaired Glucose Metabolism and Disrupted Gut Microbiota in Mice.
Klf4 Alleviates Lipopolysaccharide-Induced Inflammation by Inducing Expression of MCP-1 Induced Protein 1 to Deubiquitinate TRAF6.
Atorvastatin Attenuates Myocardial Hypertrophy in Spontaneously Hypertensive Rats via the C/EBPβ/PGC-1α/UCP3 Pathway.
Resveratrol-Induced Downregulation of NAF-1 Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine via the ROS/Nrf2 Signaling Pathways.
MiR-384 inhibits the proliferation of colorectal cancer by targeting AKT3.
XRCC1 rs1799782 (C194T) polymorphism correlated with tumor metastasis and molecular subtypes in breast cancer.
Liver-enriched activator protein 1 as an isoform of CCAAT/enhancer-binding protein beta suppresses stem cell features of hepatocellular carcinoma.
The protective effects of distal ischemic treatment on apoptosis and mitochondrial permeability in the hippocampus after cardiopulmonary resuscitation.
The oncogenic potentials and diagnostic significance of long non-coding RNA LINC00310 in breast cancer.
Oocyte-specific deletion of G(s)α induces oxidative stress and deteriorates oocyte quality in mice.
XPO1-mediated nuclear export of RNF146 protects from angiotensin II-induced endothelial cellular injury.
Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction.
MicroRNA-93 mediates cabergoline-resistance by targeting ATG7 in prolactinoma.
β-catenin regulates IRF3-mediated innate immune signalling in colorectal cancer.
Inhibitor of apoptosis protein‑like protein‑2: A novel growth accelerator for breast cancer cells.
Low-density lipoprotein receptor-related protein 6 regulates alternative pre-mRNA splicing.
Comparison of the Effects and Inhibitory Pathways of the Constituents from Gynostemma pentaphyllum against LPS-Induced Inflammatory Response.
Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7.
Administration of ubiquitin-activating enzyme UBA1 inhibitor PYR-41 attenuates angiotensin II-induced cardiac remodeling in mice.
ERα is a negative regulator of PD-L1 gene transcription in breast cancer.
Immune Activation of RAW264.7 Macrophages by Low Molecular Weight Fucoidan Extracted from New Zealand Undaria pinnatifida.
Nucleoporin35 is a novel microtubule associated protein functioning in oocyte meiotic spindle architecture.
Effects of Thymoquinone on radiation enteritis in mice.
hnRNPK modulates selective quality-control autophagy by downregulating the expression of HDAC6 in 293 cells.
Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice.
Redox-active trace metal-induced release of high mobility group box 1(HMGB1) and inflammatory cytokines in fibroblast-like synovial cells is Toll-like receptor 4 (TLR4) dependent.
Activation of α7 nicotinic acetylcholine receptor alleviates Aβ(1-42)-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.
TGF-β induces corneal endothelial senescence via increase of mitochondrial reactive oxygen species in chronic corneal allograft failure.
Annexin A5 regulates hepatocarcinoma malignancy via CRKI/II-DOCK180-RAC1 integrin and MEK-ERK pathways.
HSF4 transcriptional regulates HMOX-1 expression in HLECs.
Targeting LC3 and Beclin-1 autophagy genes suppresses proliferation, survival, migration and invasion by inhibition of Cyclin-D1 and uPAR/Integrin β1/ Src signaling in triple negative breast cancer cells.
Elucidation of the Molecular-Mechanisms and In Vivo Evaluation of the Anti-inflammatory Effect of Alginate-Derived Seleno-polymannuronate.
Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity.
Transcriptional Regulation of the Warburg Effect in Cancer by SIX1.
Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1.
High expression of NPRL2 is linked to poor prognosis in patients with prostate cancer.
An adenosine A1R-A2aR imbalance regulates low glucose/hypoxia-induced microglial activation, thereby contributing to oligodendrocyte damage through NF-κB and CREB phosphorylation.
Sofosbuvir inhibits hepatitis A virus replication in vitro assessed by a cell-based fluorescent reporter system.
CD300A promotes tumor progression by PECAM1, ADCY7 and AKT pathway in acute myeloid leukemia.
HuR regulates telomerase activity through TERC methylation.
Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice.
Ubiquitin-specific protease 11 serves as a marker of poor prognosis and promotes metastasis in hepatocellular carcinoma.
Basolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress.
Novel inhibitors of the cellular renin-angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/β-catenin pathway against renal fibrosis.
Epigenetic activation of PERP transcription by MKL1 contributes to ROS-induced apoptosis in skeletal muscle cells.
Taurocholic acid is an active promoting factor, not just a biomarker of progression of liver cirrhosis: evidence from a human metabolomic study and in vitro experiments.
Cisplatin and curcumin co-loaded nano-liposomes for the treatment of hepatocellular carcinoma.
Human Cytomegalovirus Protein pUL38 Prevents Premature Cell Death by Binding to Ubiquitin-Specific Protease 24 and Regulating Iron Metabolism.
Aberrant hypermethylation of the HOXD10 gene in papillary thyroid cancer with BRAFV600E mutation.
Exogenous oxidants activate nuclear factor kappa B through Toll-like receptor 4 stimulation to maintain inflammatory phenotype in macrophage.
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
Ubiquitin-Specific Protease USP6 Regulates the Stability of the c-Jun Protein.
Novel RAS Inhibitors Poricoic Acid ZG and Poricoic Acid ZH Attenuate Renal Fibrosis via a Wnt/β-Catenin Pathway and Targeted Phosphorylation of smad3 Signaling.
Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.
Carvedilol attenuates liver fibrosis by suppressing autophagy and promoting apoptosis in hepatic stellate cells.
Dynasore-induced potent ubiquitylation of the exon 19 deletion mutant of epidermal growth factor receptor suppresses cell growth and migration in non-small cell lung cancer.
Hypothalamic DNA methylation in rats with dihydrotestosterone-induced polycystic ovary syndrome: effects of low-frequency electro-acupuncture.
TUSC3 accelerates cancer growth and induces epithelial-mesenchymal transition by upregulating claudin-1 in non-small-cell lung cancer cells.
Fucoidan Alleviates Acetaminophen-Induced Hepatotoxicity via Oxidative Stress Inhibition and Nrf2 Translocation.
Aging-dependent decrease in the numbers of enteric neurons, interstitial cells of Cajal and expression of connexin43 in various regions of gastrointestinal tract.
Expression profiling identified IL-8 as a regulator of homotypic cell-in-cell formation.
Suppressed epithelial-mesenchymal transition and cancer stem cell properties mediate the anti-cancer effects of ethyl pyruvate via regulation of the AKT/nuclear factor-κB pathway in prostate cancer cells.
Selenium-enriched yeast inhibited β-amyloid production and modulated autophagy in a triple transgenic mouse model of Alzheimer's disease.
SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice.
Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.
Histone Methyltransferase SETDB1 Promotes the Progression of Colorectal Cancer by Inhibiting the Expression of TP53.
Rabies Virus Infection Induces Microtubule Depolymerization to Facilitate Viral RNA Synthesis by Upregulating HDAC6.
Hydrogen sulfide generation from l-cysteine in the human glioblastoma-astrocytoma U-87 MG and neuroblastoma SHSY5Y cell lines.
HMGB1 binding heptamer peptide improves survival and ameliorates brain injury in rats after cardiac arrest and cardiopulmonary resuscitation.
FAM83D, a microtubule-associated protein, promotes tumor growth and progression of human gastric cancer.
2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G(2)/M cell cycle arrest through generation of thiol oxidative stress in human esophageal cancer cells.
Palladin is a novel microtubule-associated protein responsible for spindle orientation.
Antisense Oligonucleotide-Mediated Removal of the Polyglutamine Repeat in Spinocerebellar Ataxia Type 3 Mice.
PKC θ-mediated Ca(2+)/NF-AT signalling pathway may be involved in T-cell immunosuppression in coal-burning arsenic-poisoned population.
Neuroprotective Effects of Lycium barbarum Polysaccharide on Focal Cerebral Ischemic Injury in Mice.
NOR1 Suppresses Cancer Stem-Like Cells Properties of Tumor Cells via the Inhibition of the AKT-GSK-3β-Wnt/β-catenin-ALDH1A1 Signal Circuit.
HIF-1α coordinates epigenetic activation of SIAH1 in hepatocytes in response to nutritional stress.
Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O(6)-methylguanine-DNA methyltransferase.
Inhibition of IL-8-mediated endothelial adhesion, VSMCs proliferation and migration by siRNA-TMEM98 suggests TMEM98's emerging role in atherosclerosis.
Regulation of m(6)A Transcripts by the 3'→5' RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline.
Downregulation of NAD-Dependent Deacetylase SIRT2 Protects Mouse Brain Against Ischemic Stroke.
Analysis of gene expression and functional characterization of XPR1: a pathogenic gene for primary familial brain calcification.
BRAFV600E and RET/PTC Promote Proliferation and Migration of Papillary Thyroid Carcinoma Cells In Vitro by Regulating Nuclear Factor-κB.
Stress stimuli induce cancer-stemness gene expression via Sp1 activation leading to therapeutic resistance in glioblastoma.
Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency.
PADI2-Mediated Citrullination Promotes Prostate Cancer Progression.
Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer.
A critical role of Hrd1 in the regulation of optineurin degradation and aggresome formation.
MicroRNA let-7g possesses a therapeutic potential for peripheral artery disease.
PTPIP51 regulates mouse cardiac ischemia/reperfusion through mediating the mitochondria-SR junction.
Protein synthesis inhibition and GADD34 control IFN-β heterogeneous expression in response to dsRNA.
Overexpression of WDFY2 inhibits prostate cancer cell growth and migration via inactivation of Akt pathway.
JOSD1 Negatively Regulates Type-I Interferon Antiviral Activity by Deubiquitinating and Stabilizing SOCS1.
Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming.
Long noncoding RNA CRNDE stabilized by hnRNPUL2 accelerates cell proliferation and migration in colorectal carcinoma via activating Ras/MAPK signaling pathways.
Long-Term Dietary Supplementation with Selenium-Enriched Yeast Improves Cognitive Impairment, Reverses Synaptic Deficits, and Mitigates Tau Pathology in a Triple Transgenic Mouse Model of Alzheimer's Disease.
Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats.
Knockdown of homeobox containing 1 increases the radiosensitivity of cervical cancer cells through telomere shortening.
Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via exosomes.
BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells.
Anthocyanins from Black Chokeberry (Aroniamelanocarpa Elliot) Delayed Aging-Related Degenerative Changes of Brain.
Thymoquinone Attenuates Brain Injury via an Anti-oxidative Pathway in a Status Epilepticus Rat Model.
A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity.
Functional analysis reveals that RBM10 mutations contribute to lung adenocarcinoma pathogenesis by deregulating splicing.
Characteristics of Chinese herbal medicine usage in ischemic heart disease patients among type 2 diabetes and their protection against hydrogen peroxide-mediated apoptosis in H9C2 cardiomyoblasts.
Anthocyanins Delay Ageing-Related Degenerative Changes in the Liver.
Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models.
miR-34b Modulates Skeletal Muscle Cell Proliferation and Differentiation.
HRD1 prevents apoptosis in renal tubular epithelial cells by mediating eIF2α ubiquitylation and degradation.
Autoregulation of RBM10 and cross-regulation of RBM10/RBM5 via alternative splicing-coupled nonsense-mediated decay.
MiR-30c regulates cisplatin-induced apoptosis of renal tubular epithelial cells by targeting Bnip3L and Hspa5.
Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.
Non-hemolytic enterotoxin of Bacillus cereus induces apoptosis in Vero cells.
Adipose-derived mesenchymal stem cells promote osteosarcoma proliferation and metastasis by activating the STAT3 pathway.
MiR-466b-1-3p regulates P-glycoprotein expression in rat cerebral microvascular endothelial cells.
Vav1 expression is increased in esophageal squamous cell carcinoma and indicates poor prognosis.
Atorvastatin prevents Angiotensin II induced myocardial hypertrophy in vitro via CCAAT/enhancer-binding protein β.
Satb2 Ablation Impairs Hippocampus-Based Long-Term Spatial Memory and Short-Term Working Memory and Immediate Early Genes (IEGs)-Mediated Hippocampal Synaptic Plasticity.
High-dose irradiation in combination with toll-like receptor 9 agonist CpG oligodeoxynucleotide 7909 downregulates PD-L1 expression via the NF-κB signaling pathway in non-small cell lung cancer cells.
Achaete-Scute Homolog 1 Expression Controls Cellular Differentiation of Neuroblastoma.
Sulforaphane induces apoptosis and inhibits invasion in U251MG glioblastoma cells.
Premutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding.
Rabies virus inactivates cofilin to facilitate viral budding and release.
Toll-like receptor 2-mediated MAPKs and NF-κB activation requires the GNAO1-dependent pathway in human mast cells.
MicroRNA-106a regulates phosphatase and tensin homologue expression and promotes the proliferation and invasion of ovarian cancer cells.
NLRP3 inflammasome mediates contrast media-induced acute kidney injury by regulating cell apoptosis.
Tetraiodothyroacetic acid and transthyretin silencing inhibit pro-metastatic effect of L-thyroxin in anoikis-resistant prostate cancer cells through regulation of MAPK/ERK pathway.
Niacin receptor GPR109A inhibits insulin secretion and is down-regulated in type 2 diabetic islet beta-cells.
Polypeptide N-Acetylgalactosaminyltransferase 13 Contributes to Neurogenesis via Stabilizing the Mucin-type O-Glycoprotein Podoplanin.
Characterization of Brain-Penetrant Pyrimidine-Containing Molecules with Differential Microtubule-Stabilizing Activities Developed as Potential Therapeutic Agents for Alzheimer's Disease and Related Tauopathies.
CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway.
Pdcd4 restrains the self-renewal and white-to-beige transdifferentiation of adipose-derived stem cells.
Cell Autonomous and Nonautonomous Function of CUL4B in Mouse Spermatogenesis.
Renalase attenuates hypertension, renal injury and cardiac remodelling in rats with subtotal nephrectomy.
Go is required for the release of IL-8 and TNF-α, but not degranulation in human mast cells.
Deletion of Brg1 causes abnormal hair cell planer polarity, hair cell anchorage, and scar formation in mouse cochlea.
miR-1301 promotes prostate cancer proliferation through directly targeting PPP2R2C.
MiR-130a regulates neurite outgrowth and dendritic spine density by targeting MeCP2.
Inhibition of histone deacetylases induces formation of multipolar spindles and subsequent p53-dependent apoptosis in nasopharyngeal carcinoma cells.
PfIRR Interacts with HrIGF-I and Activates the MAP-kinase and PI3-kinase Signaling Pathways to Regulate Glycogen Metabolism in Pinctada fucata.
Nogo-B receptor promotes the chemoresistance of human hepatocellular carcinoma via the ubiquitination of p53 protein.
Spatially coordinated dynamic gene transcription in living pituitary tissue.
Anxa5 mediates the in vitro malignant behaviours of murine hepatocarcinoma Hca-F cells with high lymph node metastasis potential preferentially via ERK2/p-ERK2/c-Jun/p-c-Jun(Ser73) and E-cadherin.
Protective Effects of Thymoquinone Against Convulsant Activity Induced by Lithium-Pilocarpine in a model of Status Epilepticus.
Etomidate inhibits nuclear factor-κB through decreased expression of glucocorticoid receptor in septic rats.
SUMOylated MAFB promotes colorectal cancer tumorigenesis.
Gp130-mediated STAT3 activation by S-propargyl-cysteine, an endogenous hydrogen sulfide initiator, prevents doxorubicin-induced cardiotoxicity.
The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.
miR-935 promotes gastric cancer cell proliferation by targeting SOX7.
Loss-of-function Mutation in PMVK Causes Autosomal Dominant Disseminated Superficial Porokeratosis.
ZBTB20 is required for anterior pituitary development and lactotrope specification.
Pigment Epithelium-Derived Factor Induces Endothelial Barrier Dysfunction via p38/MAPK Phosphorylation.
Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells.
High expression of transforming acidic coiled coil-containing protein 3 strongly correlates with aggressive characteristics and poor prognosis of gastric cancer.
Adipose-derived mesenchymal stem cells promote cell proliferation and invasion of epithelial ovarian cancer.
The role of autophagy in the cytotoxicity induced by recombinant human arginase in laryngeal squamous cell carcinoma.
Real Time Monitoring of Inhibition of Adipogenesis and Angiogenesis by (-)-Epigallocatechin-3-Gallate in 3T3-L1 Adipocytes and Human Umbilical Vein Endothelial Cells.
P38/MAPK contributes to endothelial barrier dysfunction via MAP4 phosphorylation-dependent microtubule disassembly in inflammation-induced acute lung injury.
Proteomic characterization of the nucleolar linker histone H1 interaction network.
Hypoxia inducible factor-1 mediates expression of miR-322: potential role in proliferation and migration of pulmonary arterial smooth muscle cells.
Bipartite Nuclear Localization Signal Controls Nuclear Import and DNA-Binding Activity of IFN Regulatory Factor 3.
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Shear-sensitive microRNA-34a modulates flow-dependent regulation of endothelial inflammation.
Cytoplasmic hnRNPK interacts with GSK3β and is essential for the osteoclast differentiation.
IFN-γ-mediated IRF1/miR-29b feedback loop suppresses colorectal cancer cell growth and metastasis by repressing IGF1.
Importin 7 and Nup358 promote nuclear import of the protein component of human telomerase.
Naringin inhibits TNF-α induced oxidative stress and inflammatory response in HUVECs via Nox4/NF-κ B and PI3K/Akt pathways.
Novel approaches for the identification of nuclear transport receptor substrates.
Insulin-like growth factor binding protein 4 enhances cardiomyocytes induction in murine-induced pluripotent stem cells.
Probing the cell death signaling pathway of HepG2 cell line induced by copper-1,10-phenanthroline complex.
The role of autophagy in the neurotoxicity of cationic PAMAM dendrimers.
Chromatin-remodeling factors mediate the balance of sense-antisense transcription at the FGF2 locus.
Pin1 promotes GR transactivation by enhancing recruitment to target genes.
Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry.
Several phenylalanine-glycine motives in the nucleoporin Nup214 are essential for binding of the nuclear export receptor CRM1.
Resolution doubling in fluorescence microscopy with confocal spinning-disk image scanning microscopy.
Long-distance intercellular connectivity between cardiomyocytes and cardiofibroblasts mediated by membrane nanotubes.
Intercellular transportation of quantum dots mediated by membrane nanotubes.
Regulation of FGF-2 by an endogenous antisense RNA: effects on cell adhesion and cell-cycle progression.
Regulation of fibroblast growth factor-2 by an endogenous antisense RNA and by argonaute-2.
CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells.
Hu K, Xie L, Wu W, Zhang J, Li Y, He J, Zhang Y, Lu D, Koeffler HP, Lin L, Yin D
International journal of biological sciences 2024;20(8):3140-3155
International journal of biological sciences 2024;20(8):3140-3155
Colchicine Blocks Abdominal Aortic Aneurysm Development by Maintaining Vascular Smooth Muscle Cell Homeostasis.
Chen M, Yang D, Zhou Y, Yang C, Lin W, Li J, Liu J, Ye J, Huang W, Ma W, Li W, Chen J, Zhang Y, Shi GP, Luo J, Li J, Luo S
International journal of biological sciences 2024;20(6):2092-2110
International journal of biological sciences 2024;20(6):2092-2110
Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-κB and Keap1-Nrf2-HO-1 signaling pathways in macrophages.
Luo L, Wang H, Xiong J, Chen X, Shen X, Zhang H
PloS one 2024;19(5):e0303556
PloS one 2024;19(5):e0303556
Astragaloside IV attenuates renal tubule injury in DKD rats via suppression of CD36-mediated NLRP3 inflammasome activation.
Li X, Dong X, Zhang L, Zhang S, Huang W, Wang C, Huo Z, Li X, Zhang X, Jia X, Chen G, Kuang B
Frontiers in pharmacology 2024;15:1285797
Frontiers in pharmacology 2024;15:1285797
Anillin contributes to prostate cancer progression through the regulation of IGF2BP1 to promote c-Myc and MAPK signaling.
Liu J, Wang S, Zhang C, Wei Z, Han D, Song Y, Song X, Chao F, Wu Z, Xu G, Chen G
American journal of cancer research 2024;14(2):490-506
American journal of cancer research 2024;14(2):490-506
Cyy-287, a novel pyrimidine-2,4-diamine derivative, efficiently mitigates inflammatory responses, fibrosis, and lipid synthesis in obesity-induced cardiac and hepatic dysfunction.
Ni J, Zhang X, Huang H, Ni Z, Luo J, Zhong Y, Hui M, Liu Z, Qian J, Zhang Q
PeerJ 2024;12:e17009
PeerJ 2024;12:e17009
Insufficient KIF15 during porcine oocyte ageing induces HDAC6-based microtubule instability.
Yin YX, Ding MQ, Yi Y, Zou YJ, Liao BY, Sun SC
Theriogenology 2024 Sep 15;226:49-56
Theriogenology 2024 Sep 15;226:49-56
Edaravone Maintains AQP4 Polarity Via OS/MMP9/β-DG Pathway in an Experimental Intracerebral Hemorrhage Mouse Model.
Wang Z, Li Y, Wang Z, Liao Y, Ye Q, Tang S, Wei T, Xiao P, Huang J, Lu W
Molecular neurobiology 2024 Oct;61(10):7639-7658
Molecular neurobiology 2024 Oct;61(10):7639-7658
The activation of P38MAPK Signaling Pathway Impedes the Delivery of the Cx43 to the Intercalated Discs During Cardiac Ischemia-Reperfusion Injury.
Huang X, Bai X, Yi J, Hu T, An L, Gao H
Journal of cardiovascular translational research 2024 Oct;17(5):1140-1154
Journal of cardiovascular translational research 2024 Oct;17(5):1140-1154
GhATL68b regulates cotton fiber cell development by ubiquitinating the enzyme required for β-oxidation of polyunsaturated fatty acids.
Li X, Huang G, Zhou Y, Wang K, Zhu Y
Plant communications 2024 Oct 14;5(10):101003
Plant communications 2024 Oct 14;5(10):101003
Inhibition of MST1 ameliorates neuronal apoptosis via GSK3β/β-TrCP/NRF2 pathway in spinal cord injury accompanied by diabetes.
Huang W, Wu D, Cai C, Yao H, Tian Z, Yang Y, Pang M, Rong L, Liu B
Redox biology 2024 May;71:103104
Redox biology 2024 May;71:103104
Effect of CTLA-4 Inhibition on Inflammation and Apoptosis After Spinal Cord Injury.
Mao W, Jiang F, Zhu C, Liu J, Lu Z, Qian Y, Xiao J
Neurochemical research 2024 May;49(5):1359-1372
Neurochemical research 2024 May;49(5):1359-1372
The balance between nuclear import and export of NLRC5 regulates MHC class I transactivation.
Zhu B, Ouda R, An N, Tanaka T, Kobayashi KS
The Journal of biological chemistry 2024 May;300(5):107205
The Journal of biological chemistry 2024 May;300(5):107205
BdTTLL3B-mediated polyglycylation is involved in the spermatogenesis in Bactrocera dorsalis.
Wu S, Ran L, Zhang T, Li Y, Xu Y, Li Y, Liu H, Wang J
International journal of biological macromolecules 2024 May;267(Pt 1):131508
International journal of biological macromolecules 2024 May;267(Pt 1):131508
Targeting PHGDH reverses the immunosuppressive phenotype of tumor-associated macrophages through α-ketoglutarate and mTORC1 signaling.
Cai Z, Li W, Hager S, Wilson JL, Afjehi-Sadat L, Heiss EH, Weichhart T, Heffeter P, Weckwerth W
Cellular & molecular immunology 2024 May;21(5):448-465
Cellular & molecular immunology 2024 May;21(5):448-465
A novel HDAC8 inhibitor H7E exerts retinoprotective effects against glaucomatous injury via ameliorating aberrant Müller glia activation and oxidative stress.
Wu LH, Cheng YW, Lin FL, Hsu KC, Wang MH, Yen JL, Wang TJ, Lin TE, Liu YC, Huang WJ, Hsiao G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116538
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116538
Development and Application of the CRISPR-dcas13d-eIF4G Translational Regulatory System to Inhibit Ferroptosis in Calcium Oxalate Crystal-Induced Kidney Injury.
He Z, Song C, Li S, Dong C, Liao W, Xiong Y, Yang S, Liu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2309234
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2309234
FTH1 overexpression using a dCasRx translation enhancement system protects the kidney from calcium oxalate crystal-induced injury.
He Z, Dong C, Song T, Zhou J, Xu T, He R, Li S
Cellular & molecular biology letters 2024 May 7;29(1):65
Cellular & molecular biology letters 2024 May 7;29(1):65
Activation of Nrf2/HO-1 signaling pathway exacerbates cholestatic liver injury.
Wang Y, Fu X, Zeng L, Hu Y, Gao R, Xian S, Liao S, Huang J, Yang Y, Liu J, Jin H, Klaunig J, Lu Y, Zhou S
Communications biology 2024 May 23;7(1):621
Communications biology 2024 May 23;7(1):621
NEK2 contributes to radioresistance in esophageal squamous cell carcinoma by inducing protective autophagy via regulating TRIM21.
Guo D, Zhou S, Liu R, Yao W, Li S, Zhang X, Shen W, Zhu S
Cancer cell international 2024 May 23;24(1):179
Cancer cell international 2024 May 23;24(1):179
AKAP8 promotes ovarian cancer progression and antagonizes PARP inhibitor sensitivity through regulating hnRNPUL1 transcription.
Mobet Y, Wang H, Wei Q, Liu X, Yang D, Zhao H, Yang Y, Ngono Ngane RA, Souopgui J, Xu J, Liu T, Yi P
iScience 2024 May 17;27(5):109744
iScience 2024 May 17;27(5):109744
Deciphering smooth muscle cell heterogeneity in atherosclerotic plaques and constructing model: a multi-omics approach with focus on KLF15/IGFBP4 axis.
Peng Z, Kan Q, Wang K, Deng T, Wang S, Wu R, Yao C
BMC genomics 2024 May 17;25(1):490
BMC genomics 2024 May 17;25(1):490
Bawei Chenxiang Wan ameliorates right ventricular hypertrophy in rats with high altitude heart disease by SIRT3-HIF1α-PDK/PDH signaling pathway improving fatty acid and glucose metabolism.
Han Y, Li S, Zhang Z, Ning X, Wu J, Zhang X
BMC complementary medicine and therapies 2024 May 15;24(1):190
BMC complementary medicine and therapies 2024 May 15;24(1):190
ω3-PUFA alleviates neuroinflammation by upregulating miR-107 targeting PIEZO1/NFκB p65.
Liu H, Zhou L, Yi P, Zhan F, Zhou L, Dong Y, Xiong Y, Hua F, Xu G
International immunopharmacology 2024 May 10;132:111996
International immunopharmacology 2024 May 10;132:111996
Lrg1 silencing attenuates ischemia-reperfusion renal injury by regulating autophagy and apoptosis through the TGFβ1- Smad1/5 signaling pathway.
Chen J, Zhang Z, Feng L, Liu W, Wang X, Chen H, Zou H
Archives of biochemistry and biophysics 2024 Mar;753:109892
Archives of biochemistry and biophysics 2024 Mar;753:109892
Let-7b-TLR7 Signaling Axis Contributes to the Anesthesia/Surgery-Induced Cognitive Impairment.
Deng L, Gao R, Chen H, Jiao B, Zhang C, Wei L, Yan C, Ye-Lehmann S, Zhu T, Chen C
Molecular neurobiology 2024 Mar;61(3):1818-1832
Molecular neurobiology 2024 Mar;61(3):1818-1832
RNA m(5)C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and promotes tumor progression in ovarian cancer.
Liu X, Wei Q, Yang C, Zhao H, Xu J, Mobet Y, Luo Q, Yang D, Zuo X, Chen N, Yang Y, Li L, Wang W, Yu J, Xu J, Liu T, Yi P
Experimental & molecular medicine 2024 Mar;56(3):600-615
Experimental & molecular medicine 2024 Mar;56(3):600-615
Emodin alleviates CRS4-induced mitochondrial damage via activation of the PGC1α signaling.
Dong X, Wen R, Xiong Y, Jia X, Zhang X, Li X, Zhang L, Li Z, Zhang S, Yu Y, Li Q, Wu X, Tu H, Chen Z, Xian S, Wang L, Wang C, Jia L, Wang J, Chen G
Phytotherapy research : PTR 2024 Mar;38(3):1345-1357
Phytotherapy research : PTR 2024 Mar;38(3):1345-1357
LncRNA linc01194 promotes the progress of endometrial carcinoma by up-regulating SOX2 through binding to IGF2BP1.
Huang Z, Shen F, Chen J, Xie B, Chen X, Zhao Y, Chen S
Journal of gynecologic oncology 2024 Mar;35(2):e21
Journal of gynecologic oncology 2024 Mar;35(2):e21
Inhibition of HDAC6 promotes microvascular endothelial cells to phagocytize myelin debris and reduces inflammatory response to accelerate the repair of spinal cord injury.
Wu C, Pan Y, Wang L, Liu M, Tu P, Chen S, Shi L, Yan D, Ma Y, Guo Y
CNS neuroscience & therapeutics 2024 Mar;30(3):e14439
CNS neuroscience & therapeutics 2024 Mar;30(3):e14439
Integrin β8 prevents pericyte-myofibroblast transition and renal fibrosis through inhibiting the TGF-β1/TGFBR1/Smad3 pathway in diabetic kidney disease.
Cao Y, Su H, Zeng J, Xie Y, Liu Z, Liu F, Qiu Y, Yi F, Lin J, Hammes HP, Zhang C
Translational research : the journal of laboratory and clinical medicine 2024 Mar;265:36-50
Translational research : the journal of laboratory and clinical medicine 2024 Mar;265:36-50
Exercise-inducible circulating extracellular vesicle irisin promotes browning and the thermogenic program in white adipose tissue.
Shi H, Hao X, Sun Y, Zhao Y, Wang Y, Cao X, Gong Z, Ji S, Lu J, Yan Y, Yu X, Luo X, Wang J, Wang H
Acta physiologica (Oxford, England) 2024 Mar;240(3):e14103
Acta physiologica (Oxford, England) 2024 Mar;240(3):e14103
Expression and in vitro effect of phoenixin-14 on the porcine ovarian granulosa cells.
Kurowska P, Mlyczyńska E, Wajda J, Król K, Pich K, Guzman P, Greggio A, Szkraba O, Opydo M, Dupont J, Rak A
Reproductive biology 2024 Mar;24(1):100827
Reproductive biology 2024 Mar;24(1):100827
Physical and social environmental enrichment alleviate ferroptosis and inflammation with inhibition of TLR4/MyD88/p38MAPK pathway in chronic cerebral hypoperfusion rats.
Fan B, Zhang Y, Luo Q, Hao C, Liao W
Brain research bulletin 2024 Mar;208:110897
Brain research bulletin 2024 Mar;208:110897
STING activation in cardiomyocytes drives hypertrophy-associated heart failure via NF-κB-mediated inflammatory response.
Wang L, Zhang S, Liu H, Gao L, He L, Chen Y, Zhang J, Yang M, He C
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166997
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166997
Ubiquitination of cytoplasmic HMGB1 by RNF186 regulates hepatic lipophagy in non-alcoholic fatty liver disease.
Du J, Ji X, Xu B, Du Q, Li Y, Zhou B, Liu X, Xu Z, Jiang Y, Kou B, Li Z, Cui C, Lin J
Metabolism: clinical and experimental 2024 Mar;152:155769
Metabolism: clinical and experimental 2024 Mar;152:155769
SETDB1-mediated CD147-K71 di-methylation promotes cell apoptosis in non-small cell lung cancer.
Shi MY, Wang Y, Shi Y, Tian R, Chen X, Zhang H, Wang K, Chen Z, Chen R
Genes & diseases 2024 Mar;11(2):978-992
Genes & diseases 2024 Mar;11(2):978-992
LncRNA Anxa10-203 enhances Mc1r mRNA stability to promote neuropathic pain by recruiting DHX30 in the trigeminal ganglion.
Liu Y, Liu F, Li Y, Li Y, Feng Y, Zhao J, Zhou C, Li C, Shen J, Zhang Y
The journal of headache and pain 2024 Mar 4;25(1):28
The journal of headache and pain 2024 Mar 4;25(1):28
Rag-GTPase-TFEB/TFE3 axis controls B cell mitochondrial fitness and humoral immunity independent of mTORC1.
Zhu X, Wu Y, Li Y, Zhou X, Watzlawik JO, Chen YM, Raybuck AL, Billadeau D, Shapiro V, Springer W, Sun J, Boothby MR, Zeng H
Research square 2024 Mar 29;
Research square 2024 Mar 29;
USP15 facilitates the progression of bladder cancer by amplifying the activation of the NF-κB signaling pathway.
Li Y, Jiang C, Liu Q, Zhou P, Tian D, Zeng Y, Xiang M
Aging 2024 Mar 28;16(8):6757-6772
Aging 2024 Mar 28;16(8):6757-6772
Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice.
Feng T, Du H, Yang C, Wang Y, Hu F
Acta neuropathologica 2024 Mar 25;147(1):62
Acta neuropathologica 2024 Mar 25;147(1):62
CDKL1 potentiates the antitumor efficacy of radioimmunotherapy by binding to transcription factor YBX1 and blocking PD-L1 expression in lung cancer.
Li Z, Xue H, Li J, Zheng Z, Liu Z, Dong X, Wang H, Chen J, Xu S
Journal of experimental & clinical cancer research : CR 2024 Mar 22;43(1):89
Journal of experimental & clinical cancer research : CR 2024 Mar 22;43(1):89
Pan-cancer analysis of DDIT4 identifying its prognostic value and function in acute myeloid leukemia.
Li F, Miao J, Liu R, Zhang R, He A
Journal of cancer research and clinical oncology 2024 Mar 20;150(3):144
Journal of cancer research and clinical oncology 2024 Mar 20;150(3):144
Postweaning Development Influences Endogenous VPAC(1) Modulation of LTP Induced by Theta-Burst Stimulation: A Link to Maturation of the Hippocampal GABAergic System.
Gil M, Caulino-Rocha A, Bento M, Rodrigues NC, Silva-Cruz A, Ribeiro JA, Cunha-Reis D
Biomolecules 2024 Mar 20;14(3)
Biomolecules 2024 Mar 20;14(3)
A novel method to efficiently differentiate human osteoclasts from blood-derived monocytes.
Chandrabalan S, Dang L, Hansen U, Timmen M, Wehmeyer C, Stange R, Beißbarth T, Binder C, Bleckmann A, Menck K
Biological procedures online 2024 Mar 19;26(1):7
Biological procedures online 2024 Mar 19;26(1):7
Increased extracellular matrix stiffness regulates myofibroblast transformation through induction of autophagy-mediated Kindlin-2 cytoplasmic translocation.
Zhao Z, Han W, Huang G, He Y, Zuo X, Hong L
Experimental cell research 2024 Mar 15;436(2):113974
Experimental cell research 2024 Mar 15;436(2):113974
The roles of gut microbiome and metabolites associated with skin photoaging in mice by intestinal flora sequencing and metabolomics.
Qu L, Ma X, Wang F
Life sciences 2024 Mar 15;341:122487
Life sciences 2024 Mar 15;341:122487
RNA modification-related genes illuminate prognostic signature and mechanism in esophageal squamous cell carcinoma.
Han H, Sun Y, Wei W, Huang Z, Cheng M, Qiu H, Wang J, Zheng S, Liu L, Zhang Q, Zhang C, Ma J, Guo S, Wang Z, Li Z, Jiang X, Lin S, Liu Q, Zhang S
iScience 2024 Mar 15;27(3):109327
iScience 2024 Mar 15;27(3):109327
Unraveling the molecular mechanisms of lymph node metastasis in ovarian cancer: focus on MEOX1.
Li J, Sun Y, Zhi X, Sun Y, Abudousalamu Z, Lin Q, Li B, Yao L, Chen M
Journal of ovarian research 2024 Mar 14;17(1):61
Journal of ovarian research 2024 Mar 14;17(1):61
Impaired Response to Mismatch Novelty in the Li(2+)-Pilocarpine Rat Model of TLE: Correlation with Hippocampal Monoaminergic Inputs.
Nascimento C, Guerreiro-Pinto V, Pawlak S, Caulino-Rocha A, Amat-Garcia L, Cunha-Reis D
Biomedicines 2024 Mar 12;12(3)
Biomedicines 2024 Mar 12;12(3)
The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness.
Zhu X, Wu Y, Li Y, Zhou X, Watzlawik JO, Chen YM, Raybuck AL, Billadeau D, Shapiro V, Springer W, Sun J, Boothby MR, Zeng H
bioRxiv : the preprint server for biology 2024 Mar 12;
bioRxiv : the preprint server for biology 2024 Mar 12;
Kynurenine in IDO1(high) cancer cell-derived extracellular vesicles promotes angiogenesis by inducing endothelial mitophagy in ovarian cancer.
Ying X, Zheng X, Zhang X, Yin Y, Wang X
Journal of translational medicine 2024 Mar 11;22(1):267
Journal of translational medicine 2024 Mar 11;22(1):267
SCN5A-L256del and L1621F exhibit loss-of-function properties related to autosomal recessive congenital cardiac disorders presenting as sick sinus syndrome, dilated cardiomyopathy, and sudden cardiac death.
Shi J, Pan X, Wang Z, Yi M, Xie S, Zhang X, Tao D, Yang Y, Liu Y
Gene 2024 Mar 10;898:148093
Gene 2024 Mar 10;898:148093
KIAA1429 facilitates metastasis via m6A-YTHDC1-dependent RND3 down-regulation in hepatocellular carcinoma cells.
Shan M, Liu D, Sun L, Yang M, He M, Zhang Y, Xiang L, Lu L, He H, Niu D, Chen L, Li S, Chen A, He F, Wang Y, Lian J
Cancer letters 2024 Mar 1;584:216598
Cancer letters 2024 Mar 1;584:216598
OTUD4 promotes the progression of glioblastoma by deubiquitinating CDK1 and activating MAPK signaling pathway.
Ci M, Zhao G, Li C, Liu R, Hu X, Pan J, Shen Y, Zhang G, Li Y, Zhang L, Liang P, Cui H
Cell death & disease 2024 Mar 1;15(3):179
Cell death & disease 2024 Mar 1;15(3):179
AIM2 regulates autophagy to mitigate oxidative stress in aged mice with acute liver injury.
Hu C, Li M, Chen Y, Cheng W, Wang H, Zhou Y, Teng F, Ling T, Pan J, Xu H, Zheng Y, Ji G, Zhao T, You Q
Cell death discovery 2024 Mar 1;10(1):107
Cell death discovery 2024 Mar 1;10(1):107
Sphingomyelin is involved in regulating UCP1-mediated nonshivering thermogenesis.
Hu D, Zhang H, Liu Z, Ibáñez CF, Tie C, Xie M
Journal of lipid research 2024 Jun;65(6):100559
Journal of lipid research 2024 Jun;65(6):100559
Zinc-a2-Glycoprotein Acts as a Component of PNN to Protect Hippocampal Neurons from Apoptosis.
Chang K, Lin L, Cui T, Zhao H, Li J, Liu C, Gao D, Lu S
Molecular neurobiology 2024 Jun;61(6):3607-3618
Molecular neurobiology 2024 Jun;61(6):3607-3618
Myricanol attenuates sepsis-induced inflammatory responses by nuclear factor erythroid 2-related factor 2 signaling and nuclear factor kappa B/mitogen-activated protein kinase pathway via upregulating Sirtuin 1.
Liu K, Yang L, Wang P, Zhu J, Li F, Peng J, Huang K, Liang M
Inflammopharmacology 2024 Jun;32(3):1887-1901
Inflammopharmacology 2024 Jun;32(3):1887-1901
Dual inhibition of oxidative phosphorylation and glycolysis to enhance cancer therapy.
Sheng X, Wang MM, Zhang GD, Su Y, Fang HB, Yu ZH, Su Z
Bioorganic chemistry 2024 Jun;147:107325
Bioorganic chemistry 2024 Jun;147:107325
Combining cisplatin with Pinellia pedatisecta Schott lipid-soluble extract induces tumor immunogenic cell death in cervical cancer.
Wang C, Zhang M, Peng J, Zhang M, Lu C, Qi X, Luo Q, Wang Y, Li G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155504
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155504
Differential innate immune responses to fowl adenovirus serotype 4 infection in Leghorn male hepatocellular and chicken embryo fibroblast cells.
Hou X, Wang L, Zhang R, Liu G, Wang T, Wen B, Chang W, Han S, Han J, Fang J, Qi X, Wang J
Poultry science 2024 Jun;103(6):103741
Poultry science 2024 Jun;103(6):103741
GSK0660 enhances antitumor immunotherapy by reducing PD-L1 expression.
Khan B, Chen M, Wang H, Khan A, Hussain S, Shi J, Yang L, Hou Y
European journal of pharmacology 2024 Jun 5;972:176565
European journal of pharmacology 2024 Jun 5;972:176565
Remote Ischemic Postconditioning-Mediated Neuroprotection against Stroke by Promoting Ketone Body-Induced Ferroptosis Inhibition.
Huang LY, Zhang YD, Liu YN, Liang ZY, Chen J, Wang B, Yin QL, Wang PP, Wang W, Qi SH
ACS chemical neuroscience 2024 Jun 5;15(11):2223-2232
ACS chemical neuroscience 2024 Jun 5;15(11):2223-2232
Screening of potential hub genes involved in Kidney Wilms tumor via bioinformatics analysis and experimental validation.
Zeng Q, Liu T, Qin L, Wang C, Peng G, Liu Z, Tao J
BMC cancer 2024 Jun 27;24(1):771
BMC cancer 2024 Jun 27;24(1):771
Base editing correction of OCRL in Lowe syndrome: ABE-mediated functional rescue in patient-derived fibroblasts.
Chen S, Lo CH, Liu Z, Wang Q, Ning K, Li T, Sun Y
Human molecular genetics 2024 Jun 21;33(13):1142-1151
Human molecular genetics 2024 Jun 21;33(13):1142-1151
Targeted Metabolomics of Tissue and Plasma Identifies Biomarkers in Mice with NOTCH1-Dependent T-Cell Acute Lymphoblastic Leukemia.
Tosello V, Di Martino L, Piovan E
International journal of molecular sciences 2024 Jun 13;25(12)
International journal of molecular sciences 2024 Jun 13;25(12)
Terpinen-4-ol Improves Lipopolysaccharide-Induced Macrophage Inflammation by Regulating Glutamine Metabolism.
Liu Y, Tang X, Zhang H, Zheng L, Lai P, Guo C, Ma J, Chen H, Qiu L
Foods (Basel, Switzerland) 2024 Jun 12;13(12)
Foods (Basel, Switzerland) 2024 Jun 12;13(12)
Targeting Ribosome Biogenesis as a Novel Therapeutic Approach to Overcome EMT-related Chemoresistance in Breast Cancer.
Ban Y, Zou Y, Liu Y, Lee SB, Bednarczyk RB, Sheng J, Cao Y, Wong STC, Gao D
bioRxiv : the preprint server for biology 2024 Jun 11;
bioRxiv : the preprint server for biology 2024 Jun 11;
SIRT4 promotes neuronal apoptosis in models of Alzheimer's disease via the STAT2-SIRT4-mTOR pathway.
Xing D, Zhang W, Cui W, Yao X, Xiao Y, Chen L, Yuan S, Duan Y, Yu W, Pan P, Lü Y
American journal of physiology. Cell physiology 2024 Jun 1;326(6):C1697-C1709
American journal of physiology. Cell physiology 2024 Jun 1;326(6):C1697-C1709
Loss of PTPRS elicits potent metastatic capability and resistance to temozolomide in glioblastoma.
Zhang Y, Chang L, Huang P, Cao M, Hong R, Zhao X, He X, Xu L
Molecular carcinogenesis 2024 Jul;63(7):1235-1247
Molecular carcinogenesis 2024 Jul;63(7):1235-1247
Vagus nerve stimulation as a promising neuroprotection for ischemic stroke via α7nAchR-dependent inactivation of microglial NLRP3 inflammasome.
Xia XM, Duan Y, Wang YP, Han RX, Dong YF, Jiang SY, Zheng Y, Qiao C, Cao L, Lu X, Lu M
Acta pharmacologica Sinica 2024 Jul;45(7):1349-1365
Acta pharmacologica Sinica 2024 Jul;45(7):1349-1365
Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses.
Zhou X, Zhao C, Xu H, Xu Y, Zhan L, Wang P, He J, Lu T, Gu Y, Yang Y, Xu C, Chen Y, Liu Y, Zeng Y, Tian F, Chen Q, Xie X, Liu J, Hu H, Li J, Zheng Y, Guo J, Gao Z
Nature chemical biology 2024 Jul;20(7):857-866
Nature chemical biology 2024 Jul;20(7):857-866
Effects of testosterone dose on depression-like behavior among castrated adult male rats.
Ren Z, Xiao L, Xie Y, Huang Z, Lin S, Si L, Wang G
Psychoneuroendocrinology 2024 Jul;165:107046
Psychoneuroendocrinology 2024 Jul;165:107046
LncRNA AC100826.1 regulated PLCB1 to promote progression in non-small cell lung cancer.
Dai S, Wang Q, Lyu Y, Chen Z, Liu X, Zhao G, Zhang H
Thoracic cancer 2024 Jul;15(19):1477-1489
Thoracic cancer 2024 Jul;15(19):1477-1489
SELENOI Functions as a Key Modulator of Ferroptosis Pathway in Colitis and Colorectal Cancer.
Huang X, Yang X, Zhang M, Li T, Zhu K, Dong Y, Lei X, Yu Z, Lv C, Huang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(28):e2404073
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(28):e2404073
Inhibition of METTL3 Alleviates NLRP3 Inflammasome Activation via Increasing Ubiquitination of NEK7.
Zhou X, Yang X, Huang S, Lin G, Lei K, Wang Q, Lin W, Li H, Qi X, Seriwatanachai D, Yang S, Shao B, Yuan Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(26):e2308786
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(26):e2308786
The potential role of the prolyl isomerase Pin1 during blastocyst implantation and uterine decidualization in mice.
Xu R, Li Y, Li S, Wang N, Lin S, Du T, Wang F, Zhang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 31;38(14):e23839
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 31;38(14):e23839
DNA demethylase TET2-mediated reduction of HADHB expression contributes to cadmium-induced malignant progression of colorectal cancer.
Li L, Jiang M, Wang W, Cao X, Ma Q, Han J, Liu Z, Huang Y, Chen Y
Ecotoxicology and environmental safety 2024 Jul 15;280:116579
Ecotoxicology and environmental safety 2024 Jul 15;280:116579
Discovery of a Covalent Inhibitor That Overcame Resistance to Venetoclax in AML Cells Overexpressing BFL-1.
Lou J, Zhou Q, Lyu X, Cen X, Liu C, Yan Z, Li Y, Tang H, Liu Q, Ding J, Lu Y, Huang H, Xie H, Zhao Y
Journal of medicinal chemistry 2024 Jul 11;67(13):10795-10830
Journal of medicinal chemistry 2024 Jul 11;67(13):10795-10830
Discovery of Novel 2-Oxoacetamide Derivatives as B3GAT3 Inhibitors for the Treatment of Hepatocellular Carcinoma.
Yin H, Zhang M, Gu C, Li Z, Hao C, Wang J, Tian L, Xu K, Hu X, Ming L, Zhang M, Wang Z, Yang Y, Zhang D, Dai B
Journal of medicinal chemistry 2024 Jul 11;67(13):10743-10773
Journal of medicinal chemistry 2024 Jul 11;67(13):10743-10773
Racgap1 knockdown results in cells with multiple cilia due to cytokinesis failure.
Basu B, Lake AVR, China B, Szymanska K, Wheway G, Bell S, Morrison E, Bond J, Johnson CA
Annals of human genetics 2024 Jan;88(1):45-57
Annals of human genetics 2024 Jan;88(1):45-57
Oridonin suppresses the growth of glioblastoma cells via inhibiting Hippo/YAP axis.
Wang C, Zhang Y, Jiang Q, Chen S, Zhang L, Qiu H
Archives of biochemistry and biophysics 2024 Jan;751:109845
Archives of biochemistry and biophysics 2024 Jan;751:109845
Sirtuin 6 protects against podocyte injury by blocking the renin-angiotensin system by inhibiting the Wnt1/β-catenin pathway.
Miao H, Wang YN, Su W, Zou L, Zhuang SG, Yu XY, Liu F, Zhao YY
Acta pharmacologica Sinica 2024 Jan;45(1):137-149
Acta pharmacologica Sinica 2024 Jan;45(1):137-149
Cysteine and glycine-rich protein 2 retards platelet-derived growth factor-BB-evoked phenotypic transition of airway smooth muscle cells by decreasing YAP/TAZ activity.
Wang H, Zhang Y, Zhong B, Geng Y, Hao J, Jin Q, Hou W
Cell biochemistry and function 2024 Jan;42(1):e3896
Cell biochemistry and function 2024 Jan;42(1):e3896
Exosomal miR-23a-3p derived from human umbilical cord mesenchymal stem cells promotes remyelination in central nervous system demyelinating diseases by targeting Tbr1/Wnt pathway.
Qin D, Wang C, Li D, Guo S
The Journal of biological chemistry 2024 Jan;300(1):105487
The Journal of biological chemistry 2024 Jan;300(1):105487
KAN0438757, a novel PFKFB3 inhibitor, prevent the progression of severe acute pancreatitis via the Nrf2/HO-1 pathway in infiltrated macrophage.
Ergashev A, Shi F, Liu Z, Pan Z, Xie H, Kong L, Wu L, Sun H, Jin Y, Kong H, Geng D, Ibrohimov A, Obeng E, Wang Y, Ma F, Chen G, Zhang T
Free radical biology & medicine 2024 Jan;210:130-145
Free radical biology & medicine 2024 Jan;210:130-145
An oncolytic system produces oxygen selectively in pancreatic tumor cells to alleviate hypoxia and improve immune activation.
Chen Y, Wang J, Huang Y, Wu J, Wang Y, Chen A, Guo Q, Zhang Y, Zhang S, Wang L, Zou X, Li X
Pharmacological research 2024 Jan;199:107053
Pharmacological research 2024 Jan;199:107053
Highly efficient identification of nucleocytoplasmic O-glycosylation by the TurboID-based proximity labeling method in living cells.
Long Y, Li Z, Wang L, Ao X, Zhang Z, Chen Q, Zhu D, Liu X, Liu R, Chen B, Zhu H, Su Y
Biotechnology journal 2024 Jan;19(1):e2300090
Biotechnology journal 2024 Jan;19(1):e2300090
Nuclear translocation of Axl contributes to the malignancy of oral cancer cells.
Su YF, Shen PC, Huang WY, Hung YJ, Huang TW, Lin CY, Shieh YS
Journal of dental sciences 2024 Jan;19(1):438-447
Journal of dental sciences 2024 Jan;19(1):438-447
MiR-34a functions as a tumor suppressor in oral cancer through the inhibition of the Axl/Akt/GSK-3β pathway.
Su YF, Lin CS, Shen PC, Chuang SE, Dai YH, Huang TW, Lin CY, Hung YJ, Shieh YS
Journal of dental sciences 2024 Jan;19(1):428-437
Journal of dental sciences 2024 Jan;19(1):428-437
PIM1 attenuates cisplatin-induced AKI by inhibiting Drp1 activation.
Li Y, Shi L, Zhao F, Luo Y, Zhang M, Wu X, Zhu J
Cellular signalling 2024 Jan;113:110969
Cellular signalling 2024 Jan;113:110969
Arf1 GTPase Regulates Golgi-Dependent G2/M Transition and Spindle Organization in Oocyte Meiosis.
Zhang KH, Zou YJ, Shan MM, Pan ZN, Ju JQ, Liu JC, Ji YM, Sun SC
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(4):e2303009
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(4):e2303009
Meta-analysis identifying gut microbial biomarkers of Qinghai-Tibet Plateau populations and the functionality of microbiota-derived butyrate in high-altitude adaptation.
Zhao H, Sun L, Liu J, Shi B, Zhang Y, Qu-Zong CR, Dorji T, Wang T, Yuan H, Yang J
Gut microbes 2024 Jan-Dec;16(1):2350151
Gut microbes 2024 Jan-Dec;16(1):2350151
Excessive Mitochondrial Fission Suppresses Mucosal Repair by Impairing Butyrate Metabolism in Colonocytes.
Fu SC, Qu JY, Li LX, Yang XX, Li YQ, Zuo XL
Inflammatory bowel diseases 2024 Jan 5;30(1):114-124
Inflammatory bowel diseases 2024 Jan 5;30(1):114-124
CLIC3 interacts with NAT10 to inhibit N4-acetylcytidine modification of p21 mRNA and promote bladder cancer progression.
Shuai Y, Zhang H, Liu C, Wang J, Jiang Y, Sun J, Gao X, Bo X, Xiao X, Liao X, Huang C, Chen H, Jiang G
Cell death & disease 2024 Jan 5;15(1):9
Cell death & disease 2024 Jan 5;15(1):9
ChemR23 signaling ameliorates brain injury via inhibiting NLRP3 inflammasome-mediated neuronal pyroptosis in ischemic stroke.
Liu L, Zhang J, Lu K, Zhang Y, Xu X, Deng J, Zhang X, Zhang H, Zhao Y, Wang X
Journal of translational medicine 2024 Jan 4;22(1):23
Journal of translational medicine 2024 Jan 4;22(1):23
Adipose-derived stem cell exosomes promote tumor characterization and immunosuppressive microenvironment in breast cancer.
Zhu Q, Cao Y, Yuan J, Hu Y
Cancer immunology, immunotherapy : CII 2024 Jan 31;73(2):39
Cancer immunology, immunotherapy : CII 2024 Jan 31;73(2):39
PITPNC1 Suppress CD8(+) T cell immune function and promote radioresistance in rectal cancer by modulating FASN/CD155.
Liang J, Liao L, Xie L, Tang W, Yu X, Lu Y, Chen H, Xu J, Sun L, Wu H, Cui C, Tan Y
Journal of translational medicine 2024 Jan 30;22(1):117
Journal of translational medicine 2024 Jan 30;22(1):117
Guanosine diphosphate-mannose suppresses homologous recombination repair and potentiates antitumor immunity in triple-negative breast cancer.
Ding JH, Xiao Y, Yang F, Song XQ, Xu Y, Ding XH, Ding R, Shao ZM, Di GH, Jiang YZ
Science translational medicine 2024 Jan 3;16(728):eadg7740
Science translational medicine 2024 Jan 3;16(728):eadg7740
Lamivudine, Doravirine, and Cabotegravir Downregulate the Expression of Human Endogenous Retroviruses (HERVs), Inhibit Cell Growth, and Reduce Invasive Capability in Melanoma Cell Lines.
Zanrè V, Bellinato F, Cardile A, Passarini C, Monticelli J, Di Bella S, Menegazzi M
International journal of molecular sciences 2024 Jan 28;25(3)
International journal of molecular sciences 2024 Jan 28;25(3)
Multiple reorganizations of the lateral elements of the synaptonemal complex facilitate homolog segregation in Bombyx mori oocytes.
Xiang Y, Tsuchiya D, Yu Z, Zhao X, McKinney S, Unruh J, Slaughter B, Lake CM, Hawley RS
Current biology : CB 2024 Jan 22;34(2):352-360.e4
Current biology : CB 2024 Jan 22;34(2):352-360.e4
TC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis.
Hao XL, Lv YF, Li DF, Bai FH, Gong J, Pan GQ, Su LX, Wang YL, Fu WL, Liu B, Huang L, Yan D, Tan QL, Liu JY, Guo QN
Journal of translational medicine 2024 Jan 2;22(1):6
Journal of translational medicine 2024 Jan 2;22(1):6
Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia.
Jiang X, Huang K, Sun X, Li Y, Hua L, Liu F, Huang R, Du J, Zeng H
iScience 2024 Jan 19;27(1):108691
iScience 2024 Jan 19;27(1):108691
ZDHHC5-mediated S-palmitoylation of FAK promotes its membrane localization and epithelial-mesenchymal transition in glioma.
Wang Y, Shen N, Yang Y, Xia Y, Zhang W, Lu Y, Wang Z, Yang Z, Wang Z
Cell communication and signaling : CCS 2024 Jan 17;22(1):46
Cell communication and signaling : CCS 2024 Jan 17;22(1):46
Role of histone variants H2BC1 and H2AZ.2 in H2AK119ub nucleosome organization and Polycomb gene silencing.
Shen X, Chen C, Wang Y, Zheng W, Zheng J, Jones AE, Zhu B, Zhang H, Lyons C, Rijal A, Moley JA, Cao G, Liu K, Winn R, Dickinson A, Zhang K, Wang H
bioRxiv : the preprint server for biology 2024 Jan 16;
bioRxiv : the preprint server for biology 2024 Jan 16;
YBX1 promotes type H vessel-dependent bone formation in an m5C-dependent manner.
Li YJ, Guo Q, Ye MS, Cai G, Xiao WF, Deng S, Xiao Y
JCI insight 2024 Jan 11;9(4)
JCI insight 2024 Jan 11;9(4)
Echinacoside inhibits colorectal cancer metastasis via modulating the gut microbiota and suppressing the PI3K/AKT signaling pathway.
Wei J, Zheng Z, Hou X, Jia F, Yuan Y, Yuan F, He F, Hu L, Zhao L
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116866
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116866
Deep learning enables the discovery of a novel cuproptosis-inducing molecule for the inhibition of hepatocellular carcinoma.
Yang F, Jia L, Zhou HC, Huang JN, Hou MY, Liu FT, Prabhu N, Li ZJ, Yang CB, Zou C, Nordlund P, Wang JG, Dai LY
Acta pharmacologica Sinica 2024 Feb;45(2):391-404
Acta pharmacologica Sinica 2024 Feb;45(2):391-404
Targeting ZDHHC21/FASN axis for the treatment of diffuse large B-cell lymphoma.
Liu B, Zhao X, Zhang S, Li Q, Li X, Huang D, Xia J, Ma N, Duan Y, Zhang X, Rao J
Leukemia 2024 Feb;38(2):351-364
Leukemia 2024 Feb;38(2):351-364
Epigallocatechin-3-gallate promotes wound healing response in diabetic mice by activating keratinocytes and promoting re-epithelialization.
Ning Y, Yuan Z, Wang Q, He J, Zhu W, Ren DN, Wo D
Phytotherapy research : PTR 2024 Feb;38(2):1013-1027
Phytotherapy research : PTR 2024 Feb;38(2):1013-1027
MKP-1 regulates the inflammatory activation of microglia against Alzheimer's disease.
Li J, Wang L, Zeng Q, He J, Tang Q, Wang K, He G
CNS neuroscience & therapeutics 2024 Feb;30(2):e14409
CNS neuroscience & therapeutics 2024 Feb;30(2):e14409
Dihydroxyacetone phosphate accumulation leads to podocyte pyroptosis in diabetic kidney disease.
Zhang Z, Hu H, Luo Q, Yang K, Zou Z, Shi M, Liang W
Journal of cellular and molecular medicine 2024 Feb;28(3):e18073
Journal of cellular and molecular medicine 2024 Feb;28(3):e18073
A novel hydrogen sulfide donor reduces neuroinflammation and seizures by activating ATP-sensitive potassium channels.
Kang Q, Zhu Z, Liu Z, Li F, He Y, Yang Y, Wang X, Lei S, Yuan Z, Zhu X
Neuroscience research 2024 Feb;199:21-29
Neuroscience research 2024 Feb;199:21-29
Hyaluronic Acid-Based Reactive Oxygen Species-Responsive Multifunctional Injectable Hydrogel Platform Accelerating Diabetic Wound Healing.
Shi C, Zhang Y, Wu G, Zhu Z, Zheng H, Sun X, Heng Y, Pan S, Xiu H, Zhang J, Yin Z, Yu Z, Liang B
Advanced healthcare materials 2024 Feb;13(4):e2302626
Advanced healthcare materials 2024 Feb;13(4):e2302626
WWP2 protects against sepsis-induced cardiac injury through inhibiting cardiomyocyte ferroptosis.
Li Z, Wu B, Chen J, Ye N, Ma R, Song C, Sun Y, Zhang X, Sun G
Journal of translational internal medicine 2024 Feb;12(1):35-50
Journal of translational internal medicine 2024 Feb;12(1):35-50
BHLHE40 Inhibits Ferroptosis in Pancreatic Cancer Cells via Upregulating SREBF1.
Cao Y, Wang X, Liu Y, Liu P, Qin J, Zhu Y, Zhai S, Jiang Y, Liu Y, Han L, Luo J, Zhang R, Shi M, Wang L, Tang X, Xue M, Liu J, Wang W, Wen C, Deng X, Peng C, Chen H, Cheng D, Jiang L, Shen B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2306298
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2306298
G3BP1 and SLU7 Jointly Promote Immune Evasion by Downregulating MHC-I via PI3K/Akt Activation in Bladder Cancer.
Zheng X, Chen J, Deng M, Ning K, Peng Y, Liu Z, Li X, Zhou Z, Tang H, Li Y, Kang T, Liu Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2305922
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2305922
DSPE-PEG(2000)-methotrexate nanoparticles encapsulating phenobarbital sodium kill cancer cells by inducing pyroptosis.
Yin F, Xu X, Qi J, Guo M, Wang Y, Wang Y, Ye R, Lin Q, Yang D, Zhu X, Wang J
Journal of molecular medicine (Berlin, Germany) 2024 Feb;102(2):213-229
Journal of molecular medicine (Berlin, Germany) 2024 Feb;102(2):213-229
Transcriptome-Wide N6-Methyladenosine Alternations in Pulmonary Arteries of Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats and Novel Therapeutic Targets.
Feng Y, Yu Z, Tang M, Li J, Peng B, Juaiti M, Tang Y, Liang B, Ouyang M, Liu Q, Song J
Biomedicines 2024 Feb 4;12(2)
Biomedicines 2024 Feb 4;12(2)
Molecular mechanism underlying miR-204-5p regulation of adipose-derived stem cells differentiation into cells from three germ layers.
Wang Z, Bi M, Zhe X, Wang X, Dai B, Han X, Ren B, Liang H, Liu D
Cell death discovery 2024 Feb 22;10(1):95
Cell death discovery 2024 Feb 22;10(1):95
LINC02561 promotes metastasis in HCC via HIF1-α/NDRG1/UPF1 axis.
Li SN, Li MX, Guo WW, Zhang LR, Ding YH, Wu XJ
Gene 2024 Feb 20;896:148033
Gene 2024 Feb 20;896:148033
Renal Endocytic Regulation of Vitamin D Metabolism during Maturation and Aging in Laying Hens.
Kuwata N, Mukohda H, Uchida H, Takamatsu R, Binici MM, Yamada T, Sugiyama T
Animals : an open access journal from MDPI 2024 Feb 2;14(3)
Animals : an open access journal from MDPI 2024 Feb 2;14(3)
Solobacterium moorei promotes the progression of adenomatous polyps by causing inflammation and disrupting the intestinal barrier.
Yu S, Wang X, Li Z, Jin D, Yu M, Li J, Li Y, Liu X, Zhang Q, Liu Y, Liu R, Wang X, Fang B, Zhang C, Wang R, Ren F
Journal of translational medicine 2024 Feb 17;22(1):169
Journal of translational medicine 2024 Feb 17;22(1):169
Synthesis and In Vitro Antitumor Activity Evaluation of Gefitinib-1,2,3-Triazole Derivatives.
Liu Z, Liu J, Gao E, Mao L, Hu S, Li S
Molecules (Basel, Switzerland) 2024 Feb 13;29(4)
Molecules (Basel, Switzerland) 2024 Feb 13;29(4)
Metabolites that feed upper glycolytic branches support glucose independent human cytomegalovirus replication.
Mokry RL, Purdy JG
bioRxiv : the preprint server for biology 2024 Feb 12;
bioRxiv : the preprint server for biology 2024 Feb 12;
ANLN Promotes the Proliferation and Migration of Gallbladder Cancer Cells via STRA6-Mediated Activation of PI3K/AKT Signaling.
Zhu X, Zhang Y, Bian R, Zhu J, Shi W, Ye Y
Cancers 2024 Feb 11;16(4)
Cancers 2024 Feb 11;16(4)
Empagliflozin and liraglutide ameliorate HFpEF in mice via augmenting the Erbb4 signaling pathway.
Ni XY, Feng XJ, Wang ZH, Zhang Y, Little PJ, Cao Y, Xu SW, Tang LQ, Weng JP
Acta pharmacologica Sinica 2024 Aug;45(8):1604-1617
Acta pharmacologica Sinica 2024 Aug;45(8):1604-1617
TAGLN2 targeted control of ARPC5-mediated activation of the MEK/ERK signaling pathway influences the proliferation, invasion, and metastasis of pancreatic cancer cells.
Gao Y, Hou J, Fei X, Ren L, Lu R, Liu P, Liu S, Zhu C, Wang X, Pan Y
Cellular signalling 2024 Aug;120:111227
Cellular signalling 2024 Aug;120:111227
Therapeutic potential of flavopiridol in diabetic retinopathy: Targeting DDX58.
Zhang X, Hu Q, Peng H, Huang J, Sang W, Guan J, Huang Z, Jiang B, Sun D
International immunopharmacology 2024 Aug 20;137:112504
International immunopharmacology 2024 Aug 20;137:112504
Characterization of Novel PHEX Variants in X-linked Hypophosphatemic Rickets and Genotype-PHEX Activity Correlation.
Wu H, Ying H, Zhao W, Sun Y, Wang Y, Chen X, Li G, Yao Y, Xu S, Li T, Fang L, Sun X, Wang N, Xu J, Guan Q, Xia W, Wang L, Gao L, Zhao J, Xu C
The Journal of clinical endocrinology and metabolism 2024 Aug 13;109(9):2242-2255
The Journal of clinical endocrinology and metabolism 2024 Aug 13;109(9):2242-2255
SPTBN2 suppresses ferroptosis in NSCLC cells by facilitating SLC7A11 membrane trafficking and localization.
Deng J, Lin X, Qin J, Li Q, Zhang Y, Zhang Q, Ji C, Shen S, Li Y, Zhang B, Lin N
Redox biology 2024 Apr;70:103039
Redox biology 2024 Apr;70:103039
Pimpinellin ameliorates macrophage inflammation by promoting RNF146-mediated PARP1 ubiquitination.
Yang L, Du M, Liu K, Wang P, Zhu J, Li F, Wang Z, Huang K, Liang M
Phytotherapy research : PTR 2024 Apr;38(4):1783-1798
Phytotherapy research : PTR 2024 Apr;38(4):1783-1798
Excessive processing and acetylation of OPA1 aggravate age-related hearing loss via the dysregulation of mitochondrial dynamics.
Zhang A, Pan Y, Wang H, Ding R, Zou T, Guo D, Shen Y, Ji P, Huang W, Wen Q, Wang Q, Hu H, Wu J, Xiang M, Ye B
Aging cell 2024 Apr;23(4):e14091
Aging cell 2024 Apr;23(4):e14091
Platycodon grandiflorus polysaccharide inhibits the inflammatory response of 3D4/21 cells infected with PCV2.
Guo X, Zhao X, Li L, Jiang M, Zhou A, Gao Y, Zheng P, Liu J, Zhao X
Microbial pathogenesis 2024 Apr;189:106592
Microbial pathogenesis 2024 Apr;189:106592
Tangshen Formula alleviates inflammatory injury against aged diabetic kidney disease through modulating gut microbiota composition and related amino acid metabolism.
Chen DQ, Zhang HJ, Zhang W, Feng K, Liu H, Zhao HL, Li P
Experimental gerontology 2024 Apr;188:112393
Experimental gerontology 2024 Apr;188:112393
The role of adhesion molecules in osteocalcin-induced effects on glucose and lipid metabolism in adipocytes.
Otani T, Mizokami A, Takeuchi H, Inai T, Hirata M
Biochimica et biophysica acta. Molecular cell research 2024 Apr;1871(4):119701
Biochimica et biophysica acta. Molecular cell research 2024 Apr;1871(4):119701
The regulatory role of the apelin/APJ axis in scarring: Identification of upstream and downstream mechanisms.
Shi N, Wang Y, Xia Z, Zhang J, Jia S, Jiao Y, Wang C, Wang X, Zhao J, Zhang J, Jiang D
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167125
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167125
LCP1-mediated cytoskeleton alterations involve in arsenite-triggered malignant phenotype of human immortalized prostate stromal cells.
Yang Y, Zhou M, Huang Y, Ye X, Mo Y, Huang Y, Wang S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114548
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114548
Rapamycin protects Sertoli cells against BPA-induced autophagy disorders.
Nie J, Mao Z, Zeng X, Zhao X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114510
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114510
Histone deacetylase 6 suppression of renal tubular epithelial cell promotes interstitial mineral deposition via alpha-tubulin acetylation.
Li S, Wu W, Yang B, Liu Z, Duan X, Sun X, Liu H, Zhang S, Zhou Y, Wu W
Cellular signalling 2024 Apr;116:111057
Cellular signalling 2024 Apr;116:111057
Homozygous variant in COQ7 causes autosomal recessive hereditary spastic paraplegia.
Qiu Y, Xiong Y, Wang L, Zhu M, Tan D, Hong D
Annals of clinical and translational neurology 2024 Apr;11(4):1067-1074
Annals of clinical and translational neurology 2024 Apr;11(4):1067-1074
The surface morphology of Atractylodes macrocephala polysaccharide and its inhibitory effect on PCV2 replication.
Qi C, Lv C, Jiang M, Zhao X, Gao Y, Wang Y, Zhang P, Liu J, Zhao X
Journal of the science of food and agriculture 2024 Apr;104(6):3624-3636
Journal of the science of food and agriculture 2024 Apr;104(6):3624-3636
Miz1 represses type I interferon production and limits viral clearance during influenza A virus infection.
Wu W, Arunagiri V, Do-Umehara HC, Chen C, Gu S, Biswas I, Ridge KM, Budinger GRS, Liu S, Liu J
Science signaling 2024 Apr 9;17(831):eadg7867
Science signaling 2024 Apr 9;17(831):eadg7867
Single-cell systems pharmacology identifies development-driven drug response and combination therapy in B cell acute lymphoblastic leukemia.
Huang X, Li Y, Zhang J, Yan L, Zhao H, Ding L, Bhatara S, Yang X, Yoshimura S, Yang W, Karol SE, Inaba H, Mullighan C, Litzow M, Zhu X, Zhang Y, Stock W, Jain N, Jabbour E, Kornblau SM, Konopleva M, Pui CH, Paietta E, Evans W, Yu J, Yang JJ
Cancer cell 2024 Apr 8;42(4):552-567.e6
Cancer cell 2024 Apr 8;42(4):552-567.e6
Identification of immune-associated biomarker for predicting lung adenocarcinoma: bioinformatics analysis and experiment verification of PTK6.
Xiong RH, Yang SQ, Li JW, Shen XK, Jin LM, Chen CY, Yue YT, Yu ZC, Sun QY, Jiang W, Jiang MZ, Wang XY, Song SX, Cao D, Ye HL, Zhao LR, Huang LP, Bu L
Discover oncology 2024 Apr 4;15(1):102
Discover oncology 2024 Apr 4;15(1):102
Pyxinol Fatty Acid Ester Derivatives J16 against AKI by Selectively Promoting M1 Transition to M2c Macrophages.
Wang Y, Li C, Chen J, Cui X, Wang B, Wang Y, Wang D, Liu J, Li J
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7074-7088
Journal of agricultural and food chemistry 2024 Apr 3;72(13):7074-7088
Shank3 deficiency elicits autistic-like behaviors by activating p38α in hypothalamic AgRP neurons.
Wu S, Wang J, Zhang Z, Jin X, Xu Y, Si Y, Liang Y, Ge Y, Zhan H, Peng L, Bi W, Luo D, Li M, Meng B, Guan Q, Zhao J, Gao L, He Z
Molecular autism 2024 Apr 3;15(1):14
Molecular autism 2024 Apr 3;15(1):14
Pretreatment with interleukin-15 attenuates inflammation and apoptosis by inhibiting NF-κB signaling in sepsis-induced myocardial dysfunction.
He C, Yu Y, Wang F, Li W, Ni H, Xiang M
European journal of histochemistry : EJH 2024 Apr 29;68(2)
European journal of histochemistry : EJH 2024 Apr 29;68(2)
Prognostic and Immunotherapeutic Predictive Value of CAD Gene in Hepatocellular Carcinoma: Integrated Bioinformatics and Experimental Analysis.
Wang X, Feng JK, Mao FF, Hou YC, Zhang YQ, Liu LH, Wei Q, Sun JX, Liu C, Shi J, Cheng SQ
Molecular biotechnology 2024 Apr 29;
Molecular biotechnology 2024 Apr 29;
Anti-hepatocellular carcinoma activity of Sorbaria sorbifolia by regulating VEGFR and c-Met/apoptotic pathway.
Xu ZH, Dang Y, Dong Y, Dong CY, Liu Y, Chen X, Yao Z, Shi JP
Journal of ethnopharmacology 2024 Apr 24;324:117758
Journal of ethnopharmacology 2024 Apr 24;324:117758
Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion.
Ye F, Yuan Z, Tang Y, Li J, Liu X, Sun X, Chen S, Ye X, Zeng Z, Zhang XK, Zhou H
Cell reports 2024 Apr 23;43(4):114002
Cell reports 2024 Apr 23;43(4):114002
Discovery of gefitinib-1,2,3-triazole derivatives against lung cancer via inducing apoptosis and inhibiting the colony formation.
Gao E, Wang Y, Fan GL, Xu G, Wu ZY, Liu ZJ, Liu JC, Mao LF, Hou X, Li S
Scientific reports 2024 Apr 22;14(1):9223
Scientific reports 2024 Apr 22;14(1):9223
Bulk and single-cell RNA sequencing analysis with 101 machine learning combinations reveal neutrophil extracellular trap involvement in hepatic ischemia-reperfusion injury and early allograft dysfunction.
Xie M, He Z, Bin B, Wen N, Wu J, Cai X, Sun X
International immunopharmacology 2024 Apr 20;131:111874
International immunopharmacology 2024 Apr 20;131:111874
Fatty liver disease protective MTARC1 p.A165T variant reduces the protein stability of MTARC1.
Wu M, Tie M, Hu L, Yang Y, Chen Y, Ferguson D, Chen Y, He A
Biochemical and biophysical research communications 2024 Apr 2;702:149655
Biochemical and biophysical research communications 2024 Apr 2;702:149655
Single-cell transcriptomics dissects the transcriptome alterations of hematopoietic stem cells in myelodysplastic neoplasms.
Zeng X, Wang Y, Dai M, Li W, Huang Q, Qin L, Li Y, Yan Y, Xue X, Yi F, Li W, He L, Liu Q, Qi L
Journal of translational medicine 2024 Apr 17;22(1):359
Journal of translational medicine 2024 Apr 17;22(1):359
TSHR signaling promotes hippocampal dependent memory formation through modulating Wnt5a/β-catenin mediated neurogenesis.
Li Y, Luan S, Ruan C, Li W, Zhang X, Ran Z, Bi W, Tong Y, Gao L, Zhao J, Li Y, He Z
Biochemical and biophysical research communications 2024 Apr 16;704:149723
Biochemical and biophysical research communications 2024 Apr 16;704:149723
HIF1A transcriptional regulation of COX4I2 impacts angiogenesis in pheochromocytoma.
Li X, Zhuo R, Mao Y, Fang C, Dai J, Ye L, Wang C, Sun F
Biochemical and biophysical research communications 2024 Apr 16;704:149638
Biochemical and biophysical research communications 2024 Apr 16;704:149638
Human mesenchymal stem cells derived exosomes improve ovarian function in chemotherapy-induced premature ovarian insufficiency mice by inhibiting ferroptosis through Nrf2/GPX4 pathway.
Zhou Y, Huang J, Zeng L, Yang Q, Bai F, Mai Q, Deng K
Journal of ovarian research 2024 Apr 15;17(1):80
Journal of ovarian research 2024 Apr 15;17(1):80
Programmable RNA 5-methylcytosine (m5C) modification of cellular RNAs by dCasRx conjugated methyltransferase and demethylase.
Zhang T, Zhao F, Li J, Sun X, Zhang X, Wang H, Fan P, Lai L, Li Z, Sui T
Nucleic acids research 2024 Apr 12;52(6):2776-2791
Nucleic acids research 2024 Apr 12;52(6):2776-2791
METTL3 recruiting M2-type immunosuppressed macrophages by targeting m6A-SNAIL-CXCL2 axis to promote colorectal cancer pulmonary metastasis.
Ouyang P, Li K, Xu W, Chen C, Shi Y, Tian Y, Gong J, Bao Z
Journal of experimental & clinical cancer research : CR 2024 Apr 11;43(1):111
Journal of experimental & clinical cancer research : CR 2024 Apr 11;43(1):111
The role of miR-222-2p in exosomes secreted by hexavalent chromium-induced premature senescent hepatocytes as a SASP component.
Ma Y, Li S, Ye S, Luo S, Wei L, Su Y, Zeng Y, Shi Y, Bian H, Xiao F
Environmental pollution (Barking, Essex : 1987) 2024 Apr 1;346:123535
Environmental pollution (Barking, Essex : 1987) 2024 Apr 1;346:123535
SH2B1 Tunes Hippocampal ERK Signaling to Influence Fluid Intelligence in Humans and Mice.
Du X, Yan Y, Yu J, Zhu T, Huang CC, Zhang L, Shan X, Li R, Dai Y, Lv H, Zhang XY, Feng J, Li WG, Luo Q, Li F
Research (Washington, D.C.) 2023;6:0269
Research (Washington, D.C.) 2023;6:0269
Loss of Lactate/Proton Monocarboxylate Transporter 4 Induces Ferroptosis via the AMPK/ACC Pathway and Inhibition of Autophagy on Human Bladder Cancer 5637 Cell Line.
Dong S, Zheng L, Jiang T
Journal of oncology 2023;2023:2830306
Journal of oncology 2023;2023:2830306
Aldolase A Promotes Colorectal Cancer Progression through Targeting COPS6 and Regulating MAPK Signaling Pathway.
Lu Y, Zhang Y, Wang X, Zhang H, Zhu Y, Zhang J, Sha H, Zou R, Gan Y, Sui Y, Wang J, Du T, Wu J, Feng J
Disease markers 2023;2023:1702125
Disease markers 2023;2023:1702125
Quantitative Measurement of Transthyretin Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Lyu Z, Genereux JC
Frontiers in chemical biology 2023;2
Frontiers in chemical biology 2023;2
Chronic stress promotes colorectal cancer progression by enhancing glycolysis through β2-AR/CREB1 signal pathway.
Guan Y, Yao W, Yu H, Feng Y, Zhao Y, Zhan X, Wang Y
International journal of biological sciences 2023;19(7):2006-2019
International journal of biological sciences 2023;19(7):2006-2019
Phosphorylation by IKKβ Promotes the Degradation of HMGCL via NEDD4 in Lung Cancer.
Zhong C, Xiong G, Yang H, Du X, Du J, Yao F, Fang W, Deng Y
International journal of biological sciences 2023;19(4):1110-1122
International journal of biological sciences 2023;19(4):1110-1122
Epileptiform activity influences theta-burst induced LTP in the adult hippocampus: a role for synaptic lipid raft disruption in early metaplasticity?
Carvalho-Rosa JD, Rodrigues NC, Silva-Cruz A, Vaz SH, Cunha-Reis D
Frontiers in cellular neuroscience 2023;17:1117697
Frontiers in cellular neuroscience 2023;17:1117697
Omarigliptin Protects the Integrity of the Blood-Brain Barrier After Intracerebral Hemorrhage in Mice.
Zhang Y, Liu Y, Zhang X, Yong VW, Xue M
Journal of inflammation research 2023;16:2535-2548
Journal of inflammation research 2023;16:2535-2548
Cardiolipin externalization mediates prion protein (PrP) peptide 106-126-associated mitophagy and mitochondrial dysfunction.
Yang D, Li J, Li Z, Zhao M, Wang D, Sun Z, Wen P, Gou F, Dai Y, Ji Y, Li W, Zhao D, Yang L
Frontiers in molecular neuroscience 2023;16:1163981
Frontiers in molecular neuroscience 2023;16:1163981
Multi-omics analysis reveals the involvement of origin recognition complex subunit 6 in tumor immune regulation and malignant progression.
Zhu J, Chen Q, Zeng L, Gao H, Wu T, He Y, Xu J, Pang J, Peng J, Deng Y, Han Y, Yi W
Frontiers in immunology 2023;14:1236806
Frontiers in immunology 2023;14:1236806
MIR222HG attenuates macrophage M2 polarization and allergic inflammation in allergic rhinitis by targeting the miR146a-5p/TRAF6/NF-κB axis.
Wen S, Li F, Tang Y, Dong L, He Y, Deng Y, Tao Z
Frontiers in immunology 2023;14:1168920
Frontiers in immunology 2023;14:1168920
Crosstalk of RNA methylation writers defines tumor microenvironment and alisertib resistance in breast cancer.
Zhang X, Shen L, Zhu Y, Zhai C, Zeng H, Liu X, Tao J
Frontiers in endocrinology 2023;14:1166939
Frontiers in endocrinology 2023;14:1166939
Sperm morphological abnormalities in autosomal dominant polycystic kidney disease are associated with the Hippo signaling pathway via PC1.
Shi WH, Zhou ZY, Ye MJ, Qin NX, Jiang ZR, Zhou XY, Xu NX, Cao XL, Chen SC, Huang HF, Xu CM
Frontiers in endocrinology 2023;14:1130536
Frontiers in endocrinology 2023;14:1130536
Norbergenin prevents LPS-induced inflammatory responses in macrophages through inhibiting NFκB, MAPK and STAT3 activation and blocking metabolic reprogramming.
Li W, Cai Z, Schindler F, Bahiraii S, Brenner M, Heiss EH, Weckwerth W
Frontiers in immunology 2023;14:1117638
Frontiers in immunology 2023;14:1117638
Establishment of a porcine bronchial epithelial cell line and its application to study innate immunity in the respiratory epithelium.
Fukuyama K, Zhuang T, Toyoshi E, Raya Tonetti F, Saha S, Zhou B, Ikeda-Ohtsubo W, Nishiyama K, Aso H, Villena J, Kitazawa H
Frontiers in immunology 2023;14:1117102
Frontiers in immunology 2023;14:1117102
Resolvin D1/N-formyl peptide receptor 2 ameliorates paclitaxel-induced neuropathic pain through the activation of IL-10/Nrf2/HO-1 pathway in mice.
Su CJ, Zhang JT, Zhao FL, Xu DL, Pan J, Liu T
Frontiers in immunology 2023;14:1091753
Frontiers in immunology 2023;14:1091753
Integrative analysis of the role of BOLA2B in human pan-cancer.
Liang M, Fei Y, Wang Y, Chen W, Liu Z, Xu D, Shen H, Zhou H, Tang J
Frontiers in genetics 2023;14:1077126
Frontiers in genetics 2023;14:1077126
ATRX loss suppresses the type I interferon response in sarcoma cells through chromatin remodeling.
Wang X, Jin Z, Tang S, Huang X, Wang S, Ren X, Xu M
American journal of cancer research 2023;13(8):3547-3558
American journal of cancer research 2023;13(8):3547-3558
Lactate-mediated Fascin protrusions promote cell adhesion and migration in cervical cancer.
Han X, Du S, Chen X, Min X, Dong Z, Wang Y, Zhu C, Wei F, Gao S, Cai Q
Theranostics 2023;13(7):2368-2383
Theranostics 2023;13(7):2368-2383
BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution.
Chai C, Sui K, Tang J, Yu H, Yang C, Zhang H, Li SC, Zhong JF, Wang Z, Zhang X
Theranostics 2023;13(12):3943-3963
Theranostics 2023;13(12):3943-3963
Targeting plasmodium α-tubulin-1 to block malaria transmission to mosquitoes.
Zhang G, Niu G, Hooker-Romera D, Shabani S, Ramelow J, Wang X, Butler NS, James AA, Li J
Frontiers in cellular and infection microbiology 2023;13:1132647
Frontiers in cellular and infection microbiology 2023;13:1132647
System analysis based on the migration- and invasion-related gene sets identifies the infiltration-related genes of glioma.
Shi S, Zhong J, Peng W, Yin H, Zhong D, Cui H, Sun X
Frontiers in oncology 2023;13:1075716
Frontiers in oncology 2023;13:1075716
YAP1 affects the prognosis through the regulation of stemness in endometrial cancer.
Kong W, Huang Y, Jiang P, Tu Y, Li N, Wang J, Zhou Q, Zheng Y, Gou S, Tian C, Yuan R
PeerJ 2023;11:e15891
PeerJ 2023;11:e15891
The novel role of LDHA/LDHB in the prognostic value and tumor-immune infiltration in clear cell renal cell carcinoma.
Chen J, Wu F, Cao Y, Xing Y, Liu Q, Zhao Z
PeerJ 2023;11:e15749
PeerJ 2023;11:e15749
RNA-seq reveals Nup62 as a potential regulator for cell division after traumatic brain injury in mice hippocampus.
Zhao J, Wang W, Yan K, Zhao H, Zhang Z, Wang Y, Zhu W, Chen S
PeerJ 2023;11:e14913
PeerJ 2023;11:e14913
Differences in histomorphology and expression of key lipid regulated genes of four adipose tissues from Tibetan pigs.
Lin C, Dong Z, Song J, Wang S, Yang Y, Li H, Feng Z, Pei Y
PeerJ 2023;11:e14556
PeerJ 2023;11:e14556
α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure.
Zhang N, Zhang Y, Xu J, Wang P, Wu B, Lu S, Lu X, You S, Huang X, Li M, Zou Y, Liu M, Zhao Y, Sun G, Wang W, Geng D, Liu J, Cao L, Sun Y
Cell research 2023 Sep;33(9):679-698
Cell research 2023 Sep;33(9):679-698
Electroacupuncture-Modulated MiR-106b-5p Expression Enhances Autophagy by Targeting Beclin-1 to Promote Motor Function Recovery After Spinal Cord Injury in Rats.
Guo S, Chen J, Yang Y, Li X, Tang Y, Gui Y, Chen J, Xu J
Neurospine 2023 Sep;20(3):1011-1027
Neurospine 2023 Sep;20(3):1011-1027
DWL-4-140: A allene small molecule targeting STING that alleviates lupus-like phenotype in Trex1(-/-) mice.
Du H, Kou M, Deng W, Zhou X, Zhang X, Huang Z, Ren B, Cai X, Xu S, Chen Y, Chen L, Chen C, Bao H, Chen Q, Li D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115188
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115188
The p65-LOC727924-miR-26a/KPNA3-p65 regulatory loop mediates vasoactive intestinal peptide effects on osteoarthritis chondrocytes.
Li Y, Li H, Wang L, Xie W, Yuan D, Wen Z, Zhang T, Lai J, Xiong Z, Shan Y, Jiang W
International immunopharmacology 2023 Sep;122:110518
International immunopharmacology 2023 Sep;122:110518
Inhibition of TCA cycle improves the anti-PD-1 immunotherapy efficacy in melanoma cells via ATF3-mediated PD-L1 expression and glycolysis.
Liu N, Yan M, Tao Q, Wu J, Chen J, Chen X, Peng C
Journal for immunotherapy of cancer 2023 Sep;11(9)
Journal for immunotherapy of cancer 2023 Sep;11(9)
FTO alleviates cerebral ischemia/reperfusion-induced neuroinflammation by decreasing cGAS mRNA stability in an m6A-dependent manner.
Yu Z, Zheng L, Geng Y, Zhang Y, Wang Y, You G, Cai M, Li M, Cheng X, Zan J
Cellular signalling 2023 Sep;109:110751
Cellular signalling 2023 Sep;109:110751
Osteogenic microenvironment affects palatal development through glycolysis.
Peng X, Chen J, Wang Y, Wang X, Zhao X, Zheng X, Wang Z, Yuan D, Du J
Differentiation; research in biological diversity 2023 Sep-Oct;133:1-11
Differentiation; research in biological diversity 2023 Sep-Oct;133:1-11
UBQLN2 and HSP70 participate in Parkin-mediated mitophagy by facilitating outer mitochondrial membrane rupture.
Ma Q, Xin J, Peng Q, Li N, Sun S, Hou H, Ma G, Wang N, Zhang L, Tam KY, Dussmann H, Prehn JH, Wang H, Ying Z
EMBO reports 2023 Sep 6;24(9):e55859
EMBO reports 2023 Sep 6;24(9):e55859
A natural chalcone cardamonin inhibits necroptosis and ameliorates dextran sulfate sodium (DSS)-induced colitis by targeting RIPK1/3 kinases.
Shen X, Chen H, Wen T, Liu L, Yang Y, Xie F, Wang L
European journal of pharmacology 2023 Sep 5;954:175840
European journal of pharmacology 2023 Sep 5;954:175840
Centrosome linker diversity and its function in centrosome clustering and mitotic spindle formation.
Theile L, Li X, Dang H, Mersch D, Anders S, Schiebel E
The EMBO journal 2023 Sep 4;42(17):e109738
The EMBO journal 2023 Sep 4;42(17):e109738
IGF1R-phosphorylated PYCR1 facilitates ELK4 transcriptional activity and sustains tumor growth under hypoxia.
Zheng K, Sha N, Hou G, Leng Z, Zhao Q, Zhang L, He L, Xu M, Jiang Y, Chen T
Nature communications 2023 Sep 30;14(1):6117
Nature communications 2023 Sep 30;14(1):6117
Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5.
Chen Y, Su H, Zhao J, Na Z, Jiang K, Bacchiocchi A, Loh KH, Halaban R, Wang Z, Cao X, Slavoff SA
Cell reports 2023 Sep 26;42(9):113145
Cell reports 2023 Sep 26;42(9):113145
Depletion of G9A attenuates imiquimod-induced psoriatic dermatitis via targeting EDAR-NF-κB signaling in keratinocyte.
Fang Z, Wang Y, Huang B, Chen X, Jiang R, Yin M
Cell death & disease 2023 Sep 22;14(9):627
Cell death & disease 2023 Sep 22;14(9):627
Cell Cycle Reactivation, at the Start of Neurodegeneration, Induced by Forskolin and Aniline in Differentiated Neuroblastoma Cells.
Sturiale V, Bruno F, Brancato D, D'Amico AG, Maugeri G, D'Agata V, Saccone S, Federico C
International journal of molecular sciences 2023 Sep 21;24(18)
International journal of molecular sciences 2023 Sep 21;24(18)
Human umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice.
Wei P, Jia M, Kong X, Lyu W, Feng H, Sun X, Li J, Yang JJ
Stem cell research & therapy 2023 Sep 21;14(1):263
Stem cell research & therapy 2023 Sep 21;14(1):263
Metabolic classification suggests the GLUT1/ALDOB/G6PD axis as a therapeutic target in chemotherapy-resistant pancreatic cancer.
Li Y, Tang S, Shi X, Lv J, Wu X, Zhang Y, Wang H, He J, Zhu Y, Ju Y, Zhang Y, Guo S, Yang W, Yin H, Chen L, Gao D, Jin G
Cell reports. Medicine 2023 Sep 19;4(9):101162
Cell reports. Medicine 2023 Sep 19;4(9):101162
Piper nigrum Extract Inhibits the Growth of Human Colorectal Cancer HT-29 Cells by Inducing p53-Mediated Apoptosis.
Wu R, Zhao J, Wei P, Tang M, Ma Z, Zhao Y, Du L, Wan L
Pharmaceuticals (Basel, Switzerland) 2023 Sep 19;16(9)
Pharmaceuticals (Basel, Switzerland) 2023 Sep 19;16(9)
Zymosan A Improved Doxorubicin-Induced Ventricular Remodeling by Evoking Heightened Cardiac Inflammatory Responses and Healing in Mice.
Xu G, Hao Z, Xiao W, Tan R, Yuan M, Xia Y, Liu Y
Journal of the American Heart Association 2023 Sep 19;12(18):e030200
Journal of the American Heart Association 2023 Sep 19;12(18):e030200
GPR65 inhibits human trophoblast cell adhesion through upregulation of MYLK and downregulation of fibronectin via cAMP-ERK signaling in a low pH environment.
Mao J, Feng Y, Zheng Y, Gao Y, Zhang L, Sun X, Wu Y, Zhu X, Ma F
Cell communication and signaling : CCS 2023 Sep 18;21(1):238
Cell communication and signaling : CCS 2023 Sep 18;21(1):238
Estrogen receptor alpha regulates uterine epithelial lineage specification and homeostasis.
Rizo JA, Davenport KM, Winuthayanon W, Spencer TE, Kelleher AM
iScience 2023 Sep 15;26(9):107568
iScience 2023 Sep 15;26(9):107568
Integrated clustering signature of genomic heterogeneity, stemness and tumor microenvironment predicts glioma prognosis and immunotherapy response.
Wu Y, Mao M, Wang LJ
Aging 2023 Sep 11;15(17):9086-9104
Aging 2023 Sep 11;15(17):9086-9104
N-methylpiperazine-diepoxyovatodiolide ameliorates peritoneal fibrosis via suppressing TGF-β/Smad and JAK/STAT signaling pathway.
Mo M, Zeng Y, Zeng Y, Li S, He X, Chen X, Luo Q, Liu M, Luo C, Dou X, Peng F, Long H
Chemico-biological interactions 2023 Sep 1;382:110589
Chemico-biological interactions 2023 Sep 1;382:110589
Fisetin treatment alleviates kidney injury in mice with diabetes-exacerbated atherosclerosis through inhibiting CD36/fibrosis pathway.
Zou TF, Liu ZG, Cao PC, Zheng SH, Guo WT, Wang TX, Chen YL, Duan YJ, Li QS, Liao CZ, Xie ZL, Han JH, Yang XX
Acta pharmacologica Sinica 2023 Oct;44(10):2065-2074
Acta pharmacologica Sinica 2023 Oct;44(10):2065-2074
SEMA3B-AS1 suppresses colorectal carcinoma progression by inhibiting Semaphorin 3B-dependent VEGF signaling pathway activation.
Wang YQ, Chen H, Xu S, Liao CR, Xu A, Han Y, Yang MH, Zhao L, Hu SS, Wang L, Li QY, Zhan LY, Ding YQ, Wang S
MedComm 2023 Oct;4(5):e365
MedComm 2023 Oct;4(5):e365
3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis.
Mu M, Zhang Q, Zhao C, Li X, Chen Z, Sun X, Yu J
Cancer gene therapy 2023 Oct;30(10):1414-1425
Cancer gene therapy 2023 Oct;30(10):1414-1425
Oxidative stress and inflammation are mediated via aryl hydrocarbon receptor signalling in idiopathic membranous nephropathy.
Wang YN, Miao H, Yu XY, Guo Y, Su W, Liu F, Cao G, Zhao YY
Free radical biology & medicine 2023 Oct;207:89-106
Free radical biology & medicine 2023 Oct;207:89-106
Derlin-1 ameliorates nonalcoholic hepatic steatosis by promoting ubiquitylation and degradation of FABP1.
You H, Wen X, Wang X, Zhu C, Chen H, Bu L, Zhang J, Qu S
Free radical biology & medicine 2023 Oct;207:260-271
Free radical biology & medicine 2023 Oct;207:260-271
Hepatitis B virus-related intrahepatic cholangiocarcinoma originates from hepatocytes.
Song Z, Lin S, Wu X, Ren X, Wu Y, Wen H, Qian B, Lin H, Huang Y, Zhao C, Wang N, Huang Y, Peng B, Li X, Peng H, Shen S
Hepatology international 2023 Oct;17(5):1300-1317
Hepatology international 2023 Oct;17(5):1300-1317
Atorvastatin rescues vascular endothelial injury in hypertension by WWP2-mediated ubiquitination and degradation of ATP5A.
Yin Z, You S, Zhang S, Zhang L, Wu B, Huang X, Lu S, Cao L, Zhang Y, Li D, Zhang X, Liu J, Sun Y, Zhang N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115228
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115228
Improved anti-tumor activity of fluorinated camptothecin derivatives 9-fluorocamptothecin and 7-ethyl-9-fluorocamptothecin on hepatocellular carcinoma by targeting topoisomerase I.
Zhang M, Zhu LZ, Yang CJ, Yan JX, Wang ZP, Bai YP, Peng LZ, Luo HB, Zhang ZJ, Li L, Xu CR, Liu YQ
Bioorganic chemistry 2023 Oct;139:106652
Bioorganic chemistry 2023 Oct;139:106652
MicroMagnify: A Multiplexed Expansion Microscopy Method for Pathogens and Infected Tissues.
Cheng Z, Stefani C, Skillman T, Klimas A, Lee A, DiBernardo EF, Brown KM, Milman T, Wang Y, Gallagher BR, Lagree K, Jena BP, Pulido JS, Filler SG, Mitchell AP, Hiller NL, Lacy-Hulbert A, Zhao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2302249
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2302249
Spatiotemporal Regulation of De Novo and Salvage Purine Synthesis during Brain Development.
Mizukoshi T, Yamada S, Sakakibara SI
eNeuro 2023 Oct;10(10)
eNeuro 2023 Oct;10(10)
Broad-spectrum vaccine via combined immunization routes triggers potent immunity to SARS-CoV-2 and its variants.
Xing M, Wang Y, Wang X, Liu J, Dai W, Hu G, He F, Zhao Q, Li Y, Sun L, Wang Y, Du S, Dong Z, Pang C, Hu Z, Zhang X, Xu J, Cai Q, Zhou D
Journal of virology 2023 Oct 31;97(10):e0072423
Journal of virology 2023 Oct 31;97(10):e0072423
The Antihypertensive Guanabenz Exacerbates Integrated Stress Response and Disrupts the Brain Circadian Clock.
Lin H, Naveed M, Hansen A, Anthony TG, Cao R
Clocks & sleep 2023 Oct 31;5(4):639-650
Clocks & sleep 2023 Oct 31;5(4):639-650
HLA-DPA1 overexpression inhibits cancer progression, reduces resistance to cisplatin, and correlates with increased immune infiltration in lung adenocarcinoma.
Shi K, Li QY, Zhang YQ, Huang H, Ding DX, Luo WM, Zhang J, Guo Q
Aging 2023 Oct 27;15(20):11067-11091
Aging 2023 Oct 27;15(20):11067-11091
Deacetylation of ACO2 Is Essential for Inhibiting Bombyx mori Nucleopolyhedrovirus Propagation.
Hu M, You Y, Li Y, Ma S, Li J, Miao M, Quan Y, Yu W
Viruses 2023 Oct 12;15(10)
Viruses 2023 Oct 12;15(10)
IGF2BP2 acts as a m(6)A modification regulator in laryngeal squamous cell carcinoma through facilitating CDK6 mRNA stabilization.
Tang X, Tang Q, Li S, Li M, Yang T
Cell death discovery 2023 Oct 10;9(1):371
Cell death discovery 2023 Oct 10;9(1):371
Stattic ameliorates the cecal ligation and puncture-induced cardiac injury in septic mice via IL-6-gp130-STAT3 signaling pathway.
Imbaby S, Hattori Y
Life sciences 2023 Oct 1;330:122008
Life sciences 2023 Oct 1;330:122008
Injectable microenvironment-responsive hydrogels with redox-activatable supramolecular prodrugs mediate ferroptosis-immunotherapy for postoperative tumor treatment.
Cheng Z, Xue C, Liu M, Cheng Z, Tian G, Li M, Xue R, Yao X, Zhang Y, Luo Z
Acta biomaterialia 2023 Oct 1;169:289-305
Acta biomaterialia 2023 Oct 1;169:289-305
A new ferrocene derivative blocks K-Ras localization and function by oxidative modification at His95.
Rehl KM, Selvakumar J, Pitsch RL, Hoang D, Arumugam K, Harshman SW, Gorfe AA, Cho KJ
Life science alliance 2023 Nov;6(11)
Life science alliance 2023 Nov;6(11)
The crucial role that hippocampus Cyclooxygenase-2 plays in memory.
Ni H, Guo Z, Wu Y, Wang J, Yang Y, Zhu Z, Wang D
The European journal of neuroscience 2023 Nov;58(10):4123-4136
The European journal of neuroscience 2023 Nov;58(10):4123-4136
Inhibition of TMEM16A improves cisplatin-induced acute kidney injury via preventing DRP1-mediated mitochondrial fission.
Li XL, Liu XW, Liu WL, Lin YQ, Liu J, Peng YS, Cheng LM, Du YH
Acta pharmacologica Sinica 2023 Nov;44(11):2230-2242
Acta pharmacologica Sinica 2023 Nov;44(11):2230-2242
Decrease of Cellular Communication Network Factor 1 (CCN1) Attenuates PTZ-Kindled Epilepsy in Mice.
Liao Y, Huang S, Zhang Y, Zhang H, Zhao H
Cellular and molecular neurobiology 2023 Nov;43(8):4279-4293
Cellular and molecular neurobiology 2023 Nov;43(8):4279-4293
Nuclear translocation of PKM2 mediates keratinocyte metabolic reprogramming in psoriasis.
Yang L, Zhang J, Hu C, Chen X, Yang Y, Tang H, Ding X, Yan Y
Experimental dermatology 2023 Nov;32(11):1960-1970
Experimental dermatology 2023 Nov;32(11):1960-1970
Photoactivatable base editors for spatiotemporally controlled genome editing in vivo.
Zou Q, Lu Y, Qing B, Li N, Zhou T, Pan J, Zhang X, Zhang X, Chen Y, Sun SK
Biomaterials 2023 Nov;302:122328
Biomaterials 2023 Nov;302:122328
USP51 facilitates colorectal cancer stemness and chemoresistance by forming a positive feed-forward loop with HIF1A.
Mu M, Zhang Q, Li J, Zhao C, Li X, Chen Z, Sun X, Yu J
Cell death and differentiation 2023 Nov;30(11):2393-2407
Cell death and differentiation 2023 Nov;30(11):2393-2407
Enamel defects of Axenfeld-Rieger syndrome and the role of PITX2 in its pathogenesis.
Yang Y, Zhu J, Chiba Y, Fukumoto S, Qin M, Wang X
Oral diseases 2023 Nov;29(8):3654-3664
Oral diseases 2023 Nov;29(8):3654-3664
Deubiquitinase inhibitor PR-619 potentiates colon cancer immunotherapy by inducing ferroptosis.
Wu J, Liu C, Wang T, Liu H, Wei B
Immunology 2023 Nov;170(3):439-451
Immunology 2023 Nov;170(3):439-451
Knockdown of repulsive guidance molecule a promotes polarization of microglia into an anti-inflammatory phenotype after oxygen-glucose deprivation-reoxygenation in vitro.
Shen G, Xiao H, Huang S, Yuan X, Rongrong Z, Ma Y, Qin X
Neurochemistry international 2023 Nov;170:105546
Neurochemistry international 2023 Nov;170:105546
Design and synthesis of 1H-pyrazolo[3,4-d]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors.
Zhang J, Li Y, Tang H, Zhou Q, Tong L, Ding J, Xie H, Xiong B, Liu T
Bioorganic chemistry 2023 Nov;140:106811
Bioorganic chemistry 2023 Nov;140:106811
Sanguisorba officinalis ethyl acetate extract attenuates ulcerative colitis through inhibiting PI3K-AKT/NF-κB/ STAT3 pathway uncovered by single-cell RNA sequencing.
Li C, Gong L, Jiang Y, Huo X, Huang L, Lei H, Gu Y, Wang D, Guo D, Deng Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155052
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155052
ADAMTS12 promotes oxaliplatin chemoresistance and angiogenesis in gastric cancer through VEGF upregulation.
Jiang Y, Huang J, Huang Z, Li W, Tan R, Li T, Chen Z, Tang X, Zhao Y, Qiu J, Li C, Chen H, Yang Z
Cellular signalling 2023 Nov;111:110866
Cellular signalling 2023 Nov;111:110866
Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain.
Zhou HY, Feng X, Wang LW, Zhou R, Sun H, Chen X, Lu RB, Huang Y, Guo Q, Luo XH
Cell metabolism 2023 Nov 7;35(11):1915-1930.e8
Cell metabolism 2023 Nov 7;35(11):1915-1930.e8
Defective branched-chain amino acid catabolism in dorsal root ganglia contributes to mechanical pain.
Xie H, Li J, Lian N, Xie M, Wu M, Tang K, Kang Y, Lu P, Li T
EMBO reports 2023 Nov 6;24(11):e56958
EMBO reports 2023 Nov 6;24(11):e56958
PFKP confers chemoresistance by upregulating ABCC2 transporter in non-small cell lung cancer.
Wang Z, Wu S, Chen X, Liang J, Xue F, Cho WC, Bao J, Chen B, Ye M, Ma D, Zhu C, Zhu J, Shen J
Translational lung cancer research 2023 Nov 30;12(11):2294-2309
Translational lung cancer research 2023 Nov 30;12(11):2294-2309
HDAC1-Mediated lncRNA Stimulatory Factor of Follicular Development to Inhibit the Apoptosis of Granulosa Cells and Regulate Sexual Maturity through miR-202-3p-COX1 Axis.
Zhou X, He Y, Quan H, Pan X, Zhou Y, Zhang Z, Yuan X, Li J
Cells 2023 Nov 29;12(23)
Cells 2023 Nov 29;12(23)
METTL9-SLC7A11 axis promotes hepatocellular carcinoma progression through ferroptosis inhibition.
Bi F, Qiu Y, Wu Z, Liu S, Zuo D, Huang Z, Li B, Yuan Y, Niu Y, Qiu J
Cell death discovery 2023 Nov 28;9(1):428
Cell death discovery 2023 Nov 28;9(1):428
CCDC127 regulates lipid droplet homeostasis by enhancing mitochondria-ER contacts.
Xia Y, Zhang Y, Sun Y, He L
Biochemical and biophysical research communications 2023 Nov 26;683:149116
Biochemical and biophysical research communications 2023 Nov 26;683:149116
Reduction of p11 in dorsal raphe nucleus serotonergic neurons mediates depression-like behaviors.
Li W, Shen Z, Yin X, Chang W, Chen X, Yu J, Xu S
Translational psychiatry 2023 Nov 22;13(1):359
Translational psychiatry 2023 Nov 22;13(1):359
STIM2 regulates NMDA receptor endocytosis that is induced by short-term NMDA receptor overactivation in cortical neurons.
Serwach K, Nurowska E, Klukowska M, Zablocka B, Gruszczynska-Biegala J
Cellular and molecular life sciences : CMLS 2023 Nov 21;80(12):368
Cellular and molecular life sciences : CMLS 2023 Nov 21;80(12):368
Circular RNA ZBTB46 depletion alleviates the progression of Atherosclerosis by regulating the ubiquitination and degradation of hnRNPA2B1 via the AKT/mTOR pathway.
Fu Y, Jia Q, Ren M, Bie H, Zhang X, Zhang Q, He S, Li C, Zhou H, Wang Y, Gan X, Tao Z, Chen X, Jia E
Immunity & ageing : I & A 2023 Nov 21;20(1):66
Immunity & ageing : I & A 2023 Nov 21;20(1):66
Herbal medicine formula Huazhuo Tiaozhi granule ameliorates dyslipidaemia via regulating histone lactylation and miR-155-5p biogenesis.
Yin X, Li M, Wang Y, Zhao G, Yang T, Zhang Y, Guo J, Meng T, Du R, Li H, Wang Z, Zhang J, He Q
Clinical epigenetics 2023 Nov 2;15(1):175
Clinical epigenetics 2023 Nov 2;15(1):175
A comprehensive analysis of SLC25A1 expression and its oncogenic role in pan-cancer.
You X, Huang L, Huang O, Deng Y, Shi X
Discover oncology 2023 Nov 19;14(1):207
Discover oncology 2023 Nov 19;14(1):207
Exercise improves cognitive dysfunction and neuroinflammation in mice through Histone H3 lactylation in microglia.
Han H, Zhao Y, Du J, Wang S, Yang X, Li W, Song J, Zhang S, Zhang Z, Tan Y, Hatch GM, Zhang M, Chen L
Immunity & ageing : I & A 2023 Nov 17;20(1):63
Immunity & ageing : I & A 2023 Nov 17;20(1):63
Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice.
Feng T, Du H, Hu F
bioRxiv : the preprint server for biology 2023 Nov 15;
bioRxiv : the preprint server for biology 2023 Nov 15;
Regulation of the Hippo/YAP axis by CXCR7 in the tumorigenesis of gastric cancer.
Wang T, Wang D, Sun Y, Zhuang T, Li X, Yang H, Zang Y, Liu Z, Yang P, Zhang C, Cui J, Fu M, Zhang S, Su P, Li Z, Zhu J, Ding Y
Journal of experimental & clinical cancer research : CR 2023 Nov 10;42(1):297
Journal of experimental & clinical cancer research : CR 2023 Nov 10;42(1):297
Accelerating Wound Closure With Metrnl in Normal and Diabetic Mouse Skin.
Song L, Chang X, Hu L, Liu L, Wang G, Huang Y, Xu L, Jin B, Song J, Hu L, Zhang T, Wang Y, Xiao Y, Zhang F, Shi M, Liu L, Chen Q, Guo B, Zhou Y
Diabetes 2023 Nov 1;72(11):1692-1706
Diabetes 2023 Nov 1;72(11):1692-1706
Morusinol Extracted from Morus alba Inhibits Cell Proliferation and Induces Autophagy via FOXO3a Nuclear Accumulation-Mediated Cholesterol Biosynthesis Obstruction in Colorectal Cancer.
Zhang X, Dong Z, Yang Y, Liu C, Li J, Sun W, Zhu Y, Shen Y, Wang Z, Lü M, Cui H
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16016-16031
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16016-16031
Cholesterol mediated ferroptosis suppression reveals essential roles of Coenzyme Q and squalene.
Sun Q, Liu D, Cui W, Cheng H, Huang L, Zhang R, Gu J, Liu S, Zhuang X, Lu Y, Chu B, Li J
Communications biology 2023 Nov 1;6(1):1108
Communications biology 2023 Nov 1;6(1):1108
Circular RNA transcriptome across multiple tissues reveal skeletal muscle-specific circPSME4 regulating myogenesis.
Zeng M, Yan S, Yang P, Li Q, Li J, Fan X, Liu X, Yao Y, Wang W, Chen R, Han G, Yang Y, Tang Z
International journal of biological macromolecules 2023 Nov 1;251:126322
International journal of biological macromolecules 2023 Nov 1;251:126322
cGAS-STING signaling pathway promotes hypoxia-induced renal fibrosis by regulating PFKFB3-mediated glycolysis.
Jiang A, Liu J, Wang Y, Zhang C
Free radical biology & medicine 2023 Nov 1;208:516-529
Free radical biology & medicine 2023 Nov 1;208:516-529
A phosphoglycerate mutase 1 allosteric inhibitor overcomes drug resistance to EGFR-targeted therapy via disrupting IL-6/JAK2/STAT3 signaling pathway in lung adenocarcinoma.
Liang Q, Gong M, Zou JH, Luo MY, Jiang LL, Wang C, Shen NX, Zhang MC, Xu L, Lei HM, Zhang KR, Zhang R, Zhuang G, Zhu L, Chen HZ, Zhou L, Shen Y
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 May;68:100957
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 May;68:100957
Naringenin in Si-Ni-San formula inhibits chronic psychological stress-induced breast cancer growth and metastasis by modulating estrogen metabolism through FXR/EST pathway.
Zhang J, Wang N, Zheng Y, Yang B, Wang S, Wang X, Pan B, Wang Z
Journal of advanced research 2023 May;47:189-207
Journal of advanced research 2023 May;47:189-207
OTUB1 Catalytic-Independently Deubiquitinates TGFBI and Mediates the Angiogenesis in Infantile Hemangioma by Regulating Glycolysis.
Li M, Wang X, Yang E, Li Y, Geng Y, Chen Z, Huang S, Zhang D, Wu H
Arteriosclerosis, thrombosis, and vascular biology 2023 May;43(5):654-673
Arteriosclerosis, thrombosis, and vascular biology 2023 May;43(5):654-673
Splicing factor SNRPA associated with microvascular invasion promotes hepatocellular carcinoma metastasis through activating NOTCH1/Snail pathway and is mediated by circSEC62/miR-625-5p axis.
Mo Z, Li R, Cao C, Li Y, Zheng S, Wu R, Xue J, Hu J, Meng H, Zhai H, Huang W, Zheng F, Zhou B
Environmental toxicology 2023 May;38(5):1022-1037
Environmental toxicology 2023 May;38(5):1022-1037
Rational design of a polysaccharide-based viral mimicry nanocomplex for potent gene silencing in inflammatory tissues.
Gao H, Wang S, Long Q, Cheng R, Lian W, Koivuniemi A, Ma M, Zhang B, Hirvonen J, Deng X, Liu Z, Ye X, Santos HA
Journal of controlled release : official journal of the Controlled Release Society 2023 May;357:120-132
Journal of controlled release : official journal of the Controlled Release Society 2023 May;357:120-132
Bioinformatics analysis of ferroptosis-related gene AKR1C3 as a potential biomarker of asthma and its identification in BEAS-2B cells.
Wang Y, Fan J, Tong Y, Wang L, Wang L, Weng C, Lai C, Song J, Zhang W
Computers in biology and medicine 2023 May;158:106740
Computers in biology and medicine 2023 May;158:106740
Role of Type I Cannabinoid Receptor in Sensory Neurons in Psoriasiform Skin Inflammation and Pruritus.
Liu X, Li L, Jiang J, Ge W, Huang Y, Jin Z, Liu X, Kong Y, Zhanmu O, Zeng X, Li F, Li M, Chen H
The Journal of investigative dermatology 2023 May;143(5):812-821.e3
The Journal of investigative dermatology 2023 May;143(5):812-821.e3
Down-regulation of WWP2 aggravates Type 2 diabetes mellitus-induced vascular endothelial injury through modulating ubiquitination and degradation of DDX3X.
You S, Xu J, Yin Z, Wu B, Wang P, Hao M, Cheng C, Liu M, Zhao Y, Jia P, Jiang H, Li D, Cao L, Zhang X, Zhang Y, Sun Y, Zhang N
Cardiovascular diabetology 2023 May 6;22(1):107
Cardiovascular diabetology 2023 May 6;22(1):107
MYO10 regulates genome stability and cancer inflammation through mediating mitosis.
Mayca Pozo F, Geng X, Miyagi M, Amin AL, Huang AY, Zhang Y
Cell reports 2023 May 30;42(5):112531
Cell reports 2023 May 30;42(5):112531
VEGFR-3 signaling restrains the neuron-macrophage crosstalk during neurotropic viral infection.
Qi L, Li X, Zhang F, Zhu X, Zhao Q, Yang D, Hao S, Li T, Li X, Tian T, Feng J, Sun X, Wang X, Gao S, Wang H, Ye J, Cao S, He Y, Wang H, Wei B
Cell reports 2023 May 30;42(5):112489
Cell reports 2023 May 30;42(5):112489
Transcriptional coactivation by EHMT2 restricts glucocorticoid-induced insulin resistance in a study with male mice.
Lee RA, Chang M, Yiv N, Tsay A, Tian S, Li D, Poulard C, Stallcup MR, Pufall MA, Wang JC
Nature communications 2023 May 30;14(1):3143
Nature communications 2023 May 30;14(1):3143
Dihydrotrichodimerol Purified from the Marine Fungus Acremonium citrinum Prevents NAFLD by Targeting PPARα.
Liu J, Gao S, Zhou W, Chen Y, Wang Z, Zeng Z, Zhou H, Lin T
Journal of natural products 2023 May 26;86(5):1189-1201
Journal of natural products 2023 May 26;86(5):1189-1201
Side population cells derived from hUCMSCs and hPMSCs could inhibit the malignant behaviors of Tn(+) colorectal cancer cells from modifying their O-glycosylation status.
Hu W, Ding R, Wang M, Huang P, Wei X, Hu X, Hu T
Stem cell research & therapy 2023 May 26;14(1):145
Stem cell research & therapy 2023 May 26;14(1):145
Cardamonin targets KEAP1/NRF2 signaling for protection against atherosclerosis.
Fan P, Meng H, Hao W, Zheng Y, Li H, Zhang Z, Du L, Guo X, Wang D, Wang Y, Wu H
Food & function 2023 May 22;14(10):4905-4920
Food & function 2023 May 22;14(10):4905-4920
CEBPG suppresses ferroptosis through transcriptional control of SLC7A11 in ovarian cancer.
Zhang X, Zheng X, Ying X, Xie W, Yin Y, Wang X
Journal of translational medicine 2023 May 20;21(1):334
Journal of translational medicine 2023 May 20;21(1):334
Macrophages maintain mammary stem cell activity and mammary homeostasis via TNF-α-PI3K-Cdk1/Cyclin B1 axis.
Zhou Y, Ye Z, Wei W, Zhang M, Huang F, Li J, Cai C
NPJ Regenerative medicine 2023 May 2;8(1):23
NPJ Regenerative medicine 2023 May 2;8(1):23
Inhibition of Oocyte Maturation by Follicular Extracellular Vesicles of Nonhyperandrogenic PCOS Patients Requiring IVF.
Liu C, Wang M, Yao H, Cui M, Gong X, Wang L, Sui C, Zhang H
The Journal of clinical endocrinology and metabolism 2023 May 17;108(6):1394-1404
The Journal of clinical endocrinology and metabolism 2023 May 17;108(6):1394-1404
Ginsenoside Rb1 promotes the activation of PPARα pathway via inhibiting FADD to ameliorate heart failure.
Li C, Zhang X, Li J, Liang L, Zeng J, Wen M, Pan L, Lv D, Liu M, Cheng Y, Huang H
European journal of pharmacology 2023 May 15;947:175676
European journal of pharmacology 2023 May 15;947:175676
USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1.
Zhao X, He X, Wei W, Huang K
European journal of pharmacology 2023 May 15;947:175671
European journal of pharmacology 2023 May 15;947:175671
Nanoemulsions of Hydroxysafflor Yellow A for Enhancing Physicochemical and In Vivo Performance.
Zhang Y, Zhong C, Wang Q, Zhang J, Zhao H, Huang Y, Zhao D, Yang J
International journal of molecular sciences 2023 May 12;24(10)
International journal of molecular sciences 2023 May 12;24(10)
Photoaging of polystyrene microspheres causes oxidative alterations to surface physicochemistry and enhances airway epithelial toxicity.
El Hayek E, Castillo E, In JG, Garcia M, Cerrato J, Brearley A, Gonzalez-Estrella J, Herbert G, Bleske B, Benavidez A, Hsiao H, Yin L, Campen MJ, Yu X
Toxicological sciences : an official journal of the Society of Toxicology 2023 May 12;193(1):90-102
Toxicological sciences : an official journal of the Society of Toxicology 2023 May 12;193(1):90-102
Upregulation of LPGAT1 Enhances Lung Adenocarcinoma Proliferation.
Gong H, Ma C, Li X, Zhang X, Zhang L, Chen P, Wang W, Hu Y, Huang T, Wu N, Wang X
Frontiers in bioscience (Landmark edition) 2023 May 11;28(5):89
Frontiers in bioscience (Landmark edition) 2023 May 11;28(5):89
Effect of Sublethal Concentrations of Metal Nanomaterials on Cell Energy Metabolism.
Liang C, Jiang Q, Liu Z, Yang J, Zhang J, Zhang S, Xin W
Toxics 2023 May 11;11(5)
Toxics 2023 May 11;11(5)
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
Zhou Y, Liu L, Jin B, Wu Y, Xu L, Chang X, Hu L, Wang G, Huang Y, Song L, Zhang T, Wang Y, Xiao Y, Zhang F, Shi M, Liu L, Wang T, Yan R, Guo B
Diabetes 2023 May 1;72(5):611-626
Diabetes 2023 May 1;72(5):611-626
NETs promote ROS production to induce human amniotic epithelial cell apoptosis via ERK1/2 signaling in spontaneous preterm birth.
Hu M, Li H, Li G, Wang Y, Liu J, Zhang M, Shen D, Wang X
American journal of reproductive immunology (New York, N.Y. : 1989) 2023 Mar;89(3):e13656
American journal of reproductive immunology (New York, N.Y. : 1989) 2023 Mar;89(3):e13656
RAB7A GTPase Is Involved in Mitophagosome Formation and Autophagosome-Lysosome Fusion in N2a Cells Treated with the Prion Protein Fragment 106-126.
Li Z, Lai M, Li J, Yang D, Zhao M, Wang D, Sun Z, Wen P, Gou F, Dai Y, Ji Y, Zhao D, Qiao J, Yang L
Molecular neurobiology 2023 Mar;60(3):1391-1407
Molecular neurobiology 2023 Mar;60(3):1391-1407
SARS-CoV-2 Z-RNA activates the ZBP1-RIPK3 pathway to promote virus-induced inflammatory responses.
Li S, Zhang Y, Guan Z, Ye M, Li H, You M, Zhou Z, Zhang C, Zhang F, Lu B, Zhou P, Peng K
Cell research 2023 Mar;33(3):201-214
Cell research 2023 Mar;33(3):201-214
Transportin 1 is a major nuclear import receptor of the nitric oxide synthase interacting protein.
Pörschke M, Rodríguez-González I, Parfentev I, Urlaub H, Kehlenbach RH
The Journal of biological chemistry 2023 Mar;299(3):102932
The Journal of biological chemistry 2023 Mar;299(3):102932
Artesunate delays the dysfunction of age-related intestinal epithelial barrier by mitigating endoplasmic reticulum stress/unfolded protein response.
Chen H, Sun HM, Wu B, Sun TY, Han LZ, Wang G, Shang YF, Yang S, Zhou DS
Mechanisms of ageing and development 2023 Mar;210:111760
Mechanisms of ageing and development 2023 Mar;210:111760
Pan-HDAC inhibitors augment IL2-induced proliferation of NK cells via the JAK2-STAT5B signaling pathway.
Zheng J, Lu Y, Xiao J, Duan Y, Zong S, Chen X, Hu T, Li L, Zhang Y
International immunopharmacology 2023 Mar;116:109753
International immunopharmacology 2023 Mar;116:109753
miR-330-3p alleviates the progression of atherosclerosis by downregulating AQP9.
Shan E, Yu Y, Tang W, Wang W, Wang X, Zhou S, Gao Y
Functional & integrative genomics 2023 Mar 7;23(2):77
Functional & integrative genomics 2023 Mar 7;23(2):77
A splicing silencer in SMN2 intron 6 is critical in spinal muscular atrophy.
Wang L, Ji Y, Chen Y, Bai J, Gao P, Feng P
Human molecular genetics 2023 Mar 6;32(6):971-983
Human molecular genetics 2023 Mar 6;32(6):971-983
MicroMagnify: a multiplexed expansion microscopy method for pathogens and infected tissues.
Zhao Y, Cheng Z, Stefani C, Skillman T, Klimas A, Lee A, DiBernardo E, Mueller Brown K, Milman T, Gallagher B, Lagree K, Jena B, Pulido J, Filler S, Mitchell A, Hiller L, Lacy-Hulbert A
Research square 2023 Mar 6;
Research square 2023 Mar 6;
DNAJB7 is dispensable for male fertility in mice.
Bai S, Hu M, Yu L, Chen L, Zhou J, Wu L, Xu B, Jiang X, Zhang X, Tong X, Yue Q
Reproductive biology and endocrinology : RB&E 2023 Mar 31;21(1):32
Reproductive biology and endocrinology : RB&E 2023 Mar 31;21(1):32
LncRNA SLC25A21-AS1 increases the chemosensitivity and inhibits the progression of ovarian cancer by upregulating the expression of KCNK4.
Huang K, Chen X, Geng Z, Xiong X, Cong Y, Pan X, Liu S, Ge L, Xu J, Jia X
Functional & integrative genomics 2023 Mar 30;23(2):110
Functional & integrative genomics 2023 Mar 30;23(2):110
Polynucleotide phosphorylase protects against renal tubular injury via blocking mt-dsRNA-PKR-eIF2α axis.
Zhu Y, Zhang M, Wang W, Qu S, Liu M, Rong W, Yang W, Liang H, Zeng C, Zhu X, Li L, Liu Z, Zen K
Nature communications 2023 Mar 3;14(1):1223
Nature communications 2023 Mar 3;14(1):1223
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.
Chen M, Chao B, Xu J, Liu Z, Tao Y, He J, Wang J, Yang H, Luo X, Qi H
Placenta 2023 Mar 3;133:23-31
Placenta 2023 Mar 3;133:23-31
Baitouweng decoction alleviates dextran sulfate sodium-induced ulcerative colitis by suppressing leucine-related mTORC1 signaling and reducing oxidative stress.
Wei P, He Q, Liu T, Zhang J, Shi K, Zhang J, Liu S
Journal of ethnopharmacology 2023 Mar 25;304:116095
Journal of ethnopharmacology 2023 Mar 25;304:116095
p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.
Zhu X, Huang B, Zhao F, Lian J, He L, Zhang Y, Ji L, Zhang J, Yan X, Zeng T, Ma C, Liang Y, Zhang C, Lin J
Nucleic acids research 2023 Mar 21;51(5):2195-2214
Nucleic acids research 2023 Mar 21;51(5):2195-2214
The role of small GTPases in bisphenol AF-induced multinucleation in comparison with dibutyl phthalate in the male germ cells.
Hu C, Hsiao ZH, Yin L, Yu X
Toxicological sciences : an official journal of the Society of Toxicology 2023 Mar 20;192(1):43-58
Toxicological sciences : an official journal of the Society of Toxicology 2023 Mar 20;192(1):43-58
Choroid Plexus Modulates Subventricular Zone Adult Neurogenesis and Olfaction Through Secretion of Small Extracellular Vesicles.
Liu LL, Shannahan J, Zheng W
bioRxiv : the preprint server for biology 2023 Mar 18;
bioRxiv : the preprint server for biology 2023 Mar 18;
Integrated proteomic and phosphoproteomic analysis for characterization of colorectal cancer.
Zhu H, Li Y, Guo J, Feng S, Ge H, Gu C, Wang M, Nie R, Li N, Wang Y, Wang H, Zhong J, Qian X, He G
Journal of proteomics 2023 Mar 15;274:104808
Journal of proteomics 2023 Mar 15;274:104808
Reduced inhibitory and excitatory input onto parvalbumin interneurons mediated by perineuronal net might contribute to cognitive impairments in a mouse model of sepsis-associated encephalopathy.
Zhang L, Gao YZ, Zhao CJ, Xia JY, Yang JJ, Ji MH
Neuropharmacology 2023 Mar 1;225:109382
Neuropharmacology 2023 Mar 1;225:109382
Necroptosis of macrophage is a key pathological feature in biliary atresia via GDCA/S1PR2/ZBP1/p-MLKL axis.
Yang S, Chang N, Li W, Yang T, Xue R, Liu J, Zhang L, Yao X, Chen Y, Wang H, Yang L, Huang J, Li L
Cell death & disease 2023 Mar 1;14(3):175
Cell death & disease 2023 Mar 1;14(3):175
Accumulated cholesterol protects tumours from elevated lipid peroxidation in the microenvironment.
Zhao X, Lian X, Xie J, Liu G
Redox biology 2023 Jun;62:102678
Redox biology 2023 Jun;62:102678
METTL1/WDR4-mediated tRNA m(7)G modification and mRNA translation control promote oncogenesis and doxorubicin resistance.
Wang Z, Yu P, Zou Y, Ma J, Han H, Wei W, Yang C, Zheng S, Guo S, Wang J, Liu L, Lin S
Oncogene 2023 Jun;42(23):1900-1912
Oncogene 2023 Jun;42(23):1900-1912
Magnify is a universal molecular anchoring strategy for expansion microscopy.
Klimas A, Gallagher BR, Wijesekara P, Fekir S, DiBernardo EF, Cheng Z, Stolz DB, Cambi F, Watkins SC, Brody SL, Horani A, Barth AL, Moore CI, Ren X, Zhao Y
Nature biotechnology 2023 Jun;41(6):858-869
Nature biotechnology 2023 Jun;41(6):858-869
Excessive ER-phagy contributes to ochratoxin A-induced apoptosis.
Deng H, Chen W, Zhang B, Zhang Y, Han L, Zhang Q, Yao S, Wang H, Shen XL
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113793
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113793
DBP induced autophagy and necrotic apoptosis in HepG2 cells via the mitochondrial damage pathway.
Liu H, Xu L, Zhou L, Han W, Li Z, Liu C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113782
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113782
An integrated in vitro/in silico approach to assess the anti-androgenic potency of isobavachin.
Ren L, Luo H, Zhao J, Huang S, Zhang J, Shao C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113764
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jun;176:113764
5'-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor 4A-I.
Wu C, Liu D, Zhang L, Wang J, Ding Y, Sun Z, Wang W
Frontiers of medicine 2023 Jun;17(3):476-492
Frontiers of medicine 2023 Jun;17(3):476-492
Bone marrow mesenchymal stem cell-derived exosomes reduce insulin resistance and obesity in mice via the PI3K/AKT signaling pathway.
Shi H, Hao X, Sun Y, Zhang H, Zhao Y, Wang B, Lu J, Hou W, Yan Y, Yu X, Xue L, Luo X, Wang H
FEBS open bio 2023 Jun;13(6):1015-1026
FEBS open bio 2023 Jun;13(6):1015-1026
Moshen granule ameliorates membranous nephropathy by blocking intrarenal renin-angiotensin system signalling via the Wnt1/β-catenin pathway.
Wang YN, Miao H, Hua MR, Yang JZ, Pei M, Yu HX, Wei LJ, Zou L, Zhang YM, Cao G, Zhao YY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154763
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154763
Pan-cancer analysis of Homeobox B9 as a predictor for prognosis and immunotherapy in human tumors.
Jin Q, Xu L, Wang J, Lin J, Lin H
Aging 2023 Jun 9;15(11):5096-5124
Aging 2023 Jun 9;15(11):5096-5124
The potential mechanism of qinghua quyu jianpi decoction in the treatment of ulcerative colitis based on network pharmacology and experimental validation.
Qu F, Li D, Zhang S, Zhang C, Shen A
Journal of ethnopharmacology 2023 Jun 28;310:116396
Journal of ethnopharmacology 2023 Jun 28;310:116396
Tumor-secreted IFI35 promotes proliferation and cytotoxic activity of CD8(+) T cells through PI3K/AKT/mTOR signaling pathway in colorectal cancer.
Li P, Zhou D, Chen D, Cheng Y, Chen Y, Lin Z, Zhang X, Huang Z, Cai J, Huang W, Lin Y, Ke H, Long J, Zou Y, Ye S, Lan P
Journal of biomedical science 2023 Jun 28;30(1):47
Journal of biomedical science 2023 Jun 28;30(1):47
Increased glucose availability sensitizes pancreatic cancer to chemotherapy.
Vaziri-Gohar A, Hue JJ, Abbas A, Graor HJ, Hajihassani O, Zarei M, Titomihelakis G, Feczko J, Rathore M, Chelstowska S, Loftus AW, Wang R, Zarei M, Goudarzi M, Zhang R, Willard B, Zhang L, Kresak A, Willis JE, Wang GM, Tatsuoka C, Salvino JM, Bederman I, Brunengraber H, Lyssiotis CA, Brody JR, Winter JM
Nature communications 2023 Jun 28;14(1):3823
Nature communications 2023 Jun 28;14(1):3823
An integrated bioinformatic investigation of focal adhesion-related genes in glioma followed by preliminary validation of COL1A2 in tumorigenesis.
Yao G, Deng L, Long X, Zhou Y, Zhou X
Aging 2023 Jun 22;15(13):6225-6254
Aging 2023 Jun 22;15(13):6225-6254
Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice.
Jiang X, Cheng Y, Zhu Y, Xu C, Li Q, Xing X, Li W, Zou J, Meng L, Azhar M, Cao Y, Tong X, Qin W, Zhu X, Bao J
Nature communications 2023 Jun 22;14(1):3729
Nature communications 2023 Jun 22;14(1):3729
Senescent immune cells accumulation promotes brown adipose tissue dysfunction during aging.
Feng X, Wang L, Zhou R, Zhou R, Chen L, Peng H, Huang Y, Guo Q, Luo X, Zhou H
Nature communications 2023 Jun 2;14(1):3208
Nature communications 2023 Jun 2;14(1):3208
SMYD2 inhibition-mediated hypomethylation of Ku70 contributes to impaired nonhomologous end joining repair and antitumor immunity.
Tang M, Chen G, Tu B, Hu Z, Huang Y, DuFort CC, Wan X, Mao Z, Liu Y, Zhu WG, Lu W
Science advances 2023 Jun 16;9(24):eade6624
Science advances 2023 Jun 16;9(24):eade6624
OTUD7B Activates Wnt Signaling Pathway through the Interaction with LEF1.
Lee Y, Piao HL, Kim J
Biomolecules 2023 Jun 16;13(6)
Biomolecules 2023 Jun 16;13(6)
miR-31-mediated local translation at the mitotic spindle is important for early development.
Remsburg CM, Konrad K, Stepicheva N, Testa M, Lee K, Choe L, Polson S, Bhavsar J, Huang H, Song JL
Research square 2023 Jun 14;
Research square 2023 Jun 14;
Efficient correction of ABCA4 variants by CRISPR-Cas9 in hiPSCs derived from Stargardt disease patients.
Siles L, Ruiz-Nogales S, Navinés-Ferrer A, Méndez-Vendrell P, Pomares E
Molecular therapy. Nucleic acids 2023 Jun 13;32:64-79
Molecular therapy. Nucleic acids 2023 Jun 13;32:64-79
Yi-Shen-Xie-Zhuo formula alleviates cisplatin-induced AKI by regulating inflammation and apoptosis via the cGAS/STING pathway.
Qi J, Luo Q, Zhang Q, Wu M, Zhang L, Qin L, Xue Q, Nie X
Journal of ethnopharmacology 2023 Jun 12;309:116327
Journal of ethnopharmacology 2023 Jun 12;309:116327
An O-GlcNAc transferase pathogenic variant linked to intellectual disability affects pluripotent stem cell self-renewal.
Omelková M, Fenger CD, Murray M, Hammer TB, Pravata VM, Bartual SG, Czajewski I, Bayat A, Ferenbach AT, Stavridis MP, van Aalten DMF
Disease models & mechanisms 2023 Jun 1;16(6)
Disease models & mechanisms 2023 Jun 1;16(6)
DR1-CSE/H(2)S pathway upregulates autophagy and inhibits H9C2 cells damage induced by high glucose.
Li H, Wei Y, Xi Y, Jiao L, Wen X, Wu R, Chang G, Sun F, Hao J
Acta cardiologica 2023 Jul;78(5):594-606
Acta cardiologica 2023 Jul;78(5):594-606
Enhanced BCAT1 activity and BCAA metabolism promotes RhoC activity in cancer progression.
Qian L, Li N, Lu XC, Xu M, Liu Y, Li K, Zhang Y, Hu K, Qi YT, Yao J, Wu YL, Wen W, Huang S, Chen ZJ, Yin M, Lei QY
Nature metabolism 2023 Jul;5(7):1159-1173
Nature metabolism 2023 Jul;5(7):1159-1173
Macrophage scavenger receptor A1 antagonizes abdominal aortic aneurysm via upregulating IRG1.
Huang J, Jiang Y, Ji R, Jia Y, Wang S, Zhou Z, Wang S, Wang J, Yang Q, Bai H, Zhu X, Jiang B, Ben J, Zhang H, Li X, Chen Q
Biochemical pharmacology 2023 Jul;213:115631
Biochemical pharmacology 2023 Jul;213:115631
ZCCHC3 is a stress granule zinc knuckle protein that strongly suppresses LINE-1 retrotransposition.
Goodier JL, Wan H, Soares AO, Sanchez L, Selser JM, Pereira GC, Karma S, García-Pérez JL, Kazazian HH Jr, García Cañadas MM
PLoS genetics 2023 Jul;19(7):e1010795
PLoS genetics 2023 Jul;19(7):e1010795
PPARγ inhibited tumor immune escape by inducing PD-L1 autophagic degradation.
Gou Q, Che S, Chen M, Chen H, Shi J, Hou Y
Cancer science 2023 Jul;114(7):2871-2881
Cancer science 2023 Jul;114(7):2871-2881
PPARγ agonist pioglitazone enhances colorectal cancer immunotherapy by inducing PD-L1 autophagic degradation.
Jia X, Qian J, Chen H, Liu Q, Hussain S, Jin J, Shi J, Hou Y
European journal of pharmacology 2023 Jul 5;950:175749
European journal of pharmacology 2023 Jul 5;950:175749
LncRNA DANCR deficiency promotes high glucose-induced endothelial to mesenchymal transition in cardiac microvascular cells via the FoxO1/DDAH1/ADMA signaling pathway.
Wu M, Li T, Li G, Niu B, Wu T, Yan L, Wang S, He S, Huang C, Tong W, Li N, Jiang J
European journal of pharmacology 2023 Jul 5;950:175732
European journal of pharmacology 2023 Jul 5;950:175732
Mitigation of non-alcoholic steatohepatitis via recombinant Orosomucoid 2, an acute phase protein modulating the Erk1/2-PPARγ-Cd36 pathway.
Li L, Sun H, Chen J, Ding C, Yang X, Han H, Sun Q
Cell reports 2023 Jul 25;42(7):112697
Cell reports 2023 Jul 25;42(7):112697
Suppression of TREX1 deficiency-induced cellular senescence and interferonopathies by inhibition of DNA damage response.
Du H, Xiao N, Zhang S, Zhou X, Zhang Y, Lu Z, Fu Y, Huang M, Xu S, Chen Q
iScience 2023 Jul 21;26(7):107090
iScience 2023 Jul 21;26(7):107090
NVS-ZP7-4 inhibits hepatocellular carcinoma tumorigenesis and promotes apoptosis via PI3K/AKT signaling.
Tong Q, Yan D, Cao Y, Dong X, Abula Y, Yang H, Kong P, Yi M
Scientific reports 2023 Jul 21;13(1):11795
Scientific reports 2023 Jul 21;13(1):11795
Quantitative Measurement of Secretory Protein Mistargeting by Proximity Labeling and Parallel Reaction Monitoring.
Lyu Z, Genereux JC
bioRxiv : the preprint server for biology 2023 Jul 20;
bioRxiv : the preprint server for biology 2023 Jul 20;
Schisandrin C enhances cGAS-STING pathway activation and inhibits HBV replication.
Zhao J, Xu G, Hou X, Mu W, Yang H, Shi W, Wen J, Liu T, Wu Z, Bai J, Zhang P, Wang Z, Xiao X, Zou W, Bai Z, Zhan X
Journal of ethnopharmacology 2023 Jul 15;311:116427
Journal of ethnopharmacology 2023 Jul 15;311:116427
PTRF-IL33-ZBP1 signaling mediating macrophage necroptosis contributes to HDM-induced airway inflammation.
Du J, Liu Y, Lan G, Zhou Y, Ni Y, Liao K, Zheng F, Cheng Q, Shi G, Su X
Cell death & disease 2023 Jul 15;14(7):432
Cell death & disease 2023 Jul 15;14(7):432
Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle.
Morse PT, Pérez-Mejías G, Wan J, Turner AA, Márquez I, Kalpage HA, Vaishnav A, Zurek MP, Huettemann PP, Kim K, Arroum T, De la Rosa MA, Chowdhury DD, Lee I, Brunzelle JS, Sanderson TH, Malek MH, Meierhofer D, Edwards BFP, Díaz-Moreno I, Hüttemann M
Nature communications 2023 Jul 13;14(1):4166
Nature communications 2023 Jul 13;14(1):4166
The Effect of MSTN Mutation on Bile Acid Metabolism and Lipid Metabolism in Cattle.
Wu D, Wang S, Hai C, Wang L, Pei D, Bai C, Su G, Liu X, Zhao Y, Liu Z, Yang L, Li G
Metabolites 2023 Jul 11;13(7)
Metabolites 2023 Jul 11;13(7)
A novel variant in the FBP1 gene causes fructose-1,6-bisphosphatase deficiency through increased ubiquitination.
Liang X, Liu X, Li W, Zhang L, Zhang B, Lai G, Zhao Y
Archives of biochemistry and biophysics 2023 Jul 1;742:109619
Archives of biochemistry and biophysics 2023 Jul 1;742:109619
SIRT2 promotes cell proliferation and migration through mediating ERK1/2 activation and lactosylceramide accumulation in prostate cancer.
Lin R, Yang Y, Wu E, Zhou M, Wang S, Zhang Q
The Prostate 2023 Jan;83(1):71-81
The Prostate 2023 Jan;83(1):71-81
Site-specific ubiquitination of VDAC1 restricts its oligomerization and mitochondrial DNA release in liver fibrosis.
Wu NN, Wang L, Wang L, Xu X, Lopaschuk GD, Zhang Y, Ren J
Experimental & molecular medicine 2023 Jan;55(1):269-280
Experimental & molecular medicine 2023 Jan;55(1):269-280
Formin protein DIAPH1 positively regulates PD-L1 expression and predicts the therapeutic response to anti-PD-1/PD-L1 immunotherapy.
Mei J, Cai Y, Wang H, Xu R, Zhou J, Lu J, Yang X, Pan J, Liu C, Xu J, Zhu Y
Clinical immunology (Orlando, Fla.) 2023 Jan;246:109204
Clinical immunology (Orlando, Fla.) 2023 Jan;246:109204
Translational control of murine adiponectin expression by an upstream open reading frame element.
Vasu K, Ramachandiran I, Chechi A, Khan K, Khan D, Kaufman R, Fox PL
RNA biology 2023 Jan;20(1):737-749
RNA biology 2023 Jan;20(1):737-749
Enhanced BPGM/2,3-DPG pathway activity suppresses glycolysis in hypoxic astrocytes via FIH-1 and TET2.
E G, Sun B, Liu B, Xu G, He S, Wang Y, Feng L, Wei H, Zhang J, Chen J, Gao Y, Zhang E
Brain research bulletin 2023 Jan;192:36-46
Brain research bulletin 2023 Jan;192:36-46
Kaempferol attenuates doxorubicin-induced renal tubular injury by inhibiting ROS/ASK1-mediated activation of the MAPK signaling pathway.
Wu Q, Chen J, Zheng X, Song J, Yin L, Guo H, Chen Q, Liu Y, Ma Q, Zhang H, Yang Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114087
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114087
PIM1 attenuates renal ischemia-reperfusion injury by inhibiting ASK1-JNK/P38.
Luo Y, Zhu J, Zhao F, Shi L, Li Y, Wu X
International immunopharmacology 2023 Jan;114:109563
International immunopharmacology 2023 Jan;114:109563
Myeloid-derived suppressor cells ameliorate liver mitochondrial damage to protect against autoimmune hepatitis by releasing small extracellular vesicles.
Shen M, Fan X, Shen Y, Wang X, Wu R, Wang Y, Huang C, Zhao S, Zheng Y, Men R, Luo X, Yang L
International immunopharmacology 2023 Jan;114:109540
International immunopharmacology 2023 Jan;114:109540
Tumor-intrinsic IRE1α signaling controls protective immunity in lung cancer.
Crowley MJP, Bhinder B, Markowitz GJ, Martin M, Verma A, Sandoval TA, Chae CS, Yomtoubian S, Hu Y, Chopra S, Tavarez DA, Giovanelli P, Gao D, McGraw TE, Altorki NK, Elemento O, Cubillos-Ruiz JR, Mittal V
Nature communications 2023 Jan 9;14(1):120
Nature communications 2023 Jan 9;14(1):120
NAMPT inhibition reduces macrophage inflammation through the NAD+/PARP1 pathway to attenuate liver ischemia-reperfusion injury.
Lu J, Wang M, Chen Y, Song H, Wen D, Tu J, Guo Y, Liu Z
Chemico-biological interactions 2023 Jan 5;369:110294
Chemico-biological interactions 2023 Jan 5;369:110294
MitoQ Protects Ovarian Organoids against Oxidative Stress during Oogenesis and Folliculogenesis In Vitro.
Wang J, Du H, Ma L, Feng M, Li L, Zhao X, Dai Y
International journal of molecular sciences 2023 Jan 4;24(2)
International journal of molecular sciences 2023 Jan 4;24(2)
Qi Gong Wan ameliorates adipocyte hypertrophy and inflammation in adipose tissue in a PCOS mouse model through the Nrf2/HO-1/Cyp1b1 pathway: Integrating network pharmacology and experimental validation in vivo.
Zheng R, Shen H, Li J, Zhao J, Lu L, Hu M, Lin Z, Ma H, Tan H, Hu M, Li J
Journal of ethnopharmacology 2023 Jan 30;301:115824
Journal of ethnopharmacology 2023 Jan 30;301:115824
Adipose-specific deletion of the cation channel TRPM7 inhibits TAK1 kinase-dependent inflammation and obesity in male mice.
Zhong W, Ma M, Xie J, Huang C, Li X, Gao M
Nature communications 2023 Jan 30;14(1):491
Nature communications 2023 Jan 30;14(1):491
Role of NF-κB in lead exposure-induced activation of astrocytes based on bioinformatics analysis of hippocampal proteomics.
Fan S, Weixuan W, Han H, Liansheng Z, Gang L, Jierui W, Yanshu Z
Chemico-biological interactions 2023 Jan 25;370:110310
Chemico-biological interactions 2023 Jan 25;370:110310
TAT Nanobody Exerts Antiviral Effect against PRRSV In Vitro by Targeting Viral Nucleocapsid Protein.
Ren J, Duan H, Dong H, Wu S, Du Y, Zhang G, Zhang A
International journal of molecular sciences 2023 Jan 18;24(3)
International journal of molecular sciences 2023 Jan 18;24(3)
Niche stiffness sustains cancer stemness via TAZ and NANOG phase separation.
Liu X, Ye Y, Zhu L, Xiao X, Zhou B, Gu Y, Si H, Liang H, Liu M, Li J, Jiang Q, Li J, Yu S, Ma R, Su S, Liao JY, Zhao Q
Nature communications 2023 Jan 16;14(1):238
Nature communications 2023 Jan 16;14(1):238
Recombinant human angiotensin-converting enzyme 2 plays a protective role in mice with sepsis-induced cardiac dysfunction through multiple signaling pathways dependent on converting angiotensin II to angiotensin 1-7.
Wu C, Chen Y, Zhou P, Hu Z
Annals of translational medicine 2023 Jan 15;11(1):13
Annals of translational medicine 2023 Jan 15;11(1):13
Tissue inhibitor of metalloproteinase-4 deletion in mice impacts maternal cardiac function during pregnancy and postpartum.
Thurstin AA, Egeli AN, Goldsmith EC, Spinale FG, LaVoie HA
American journal of physiology. Heart and circulatory physiology 2023 Jan 1;324(1):H85-H99
American journal of physiology. Heart and circulatory physiology 2023 Jan 1;324(1):H85-H99
Daucosterol Alleviates Alcohol-Induced Hepatic Injury and Inflammation through P38/NF-κB/NLRP3 Inflammasome Pathway.
Zhang F, Wang M, Zha Y, Zhou J, Han J, Zhang S
Nutrients 2023 Jan 1;15(1)
Nutrients 2023 Jan 1;15(1)
A novel role of Fas in delaying cellular senescence.
Saha C, Li J, Sun X, Liu X, Huang G
Heliyon 2023 Feb;9(2):e13451
Heliyon 2023 Feb;9(2):e13451
Knockout of TSC2 in Nav1.8+ neurons predisposes to the onset of normal weight obesity.
Brazill JM, Shin D, Magee K, Majumdar A, Shen IR, Cavalli V, Scheller EL
Molecular metabolism 2023 Feb;68:101664
Molecular metabolism 2023 Feb;68:101664
The TGF-β/Smad(2/3) signaling pathway is involved in Musashi2-induced invasion and metastasis of colorectal cancer.
Yu ZL, Liu J, Ning ZK, Tian HK, Wu X, Huang YF, Wu ZC, Zong Z, Zhou TC
Molecular carcinogenesis 2023 Feb;62(2):261-276
Molecular carcinogenesis 2023 Feb;62(2):261-276
Dual Antioxidant DH-217 Mitigated Cerebral Ischemia-Reperfusion Injury by Targeting IKKβ/Nrf2/HO-1 Signal Axis.
Shen M, Zheng Y, Li G, Chen Y, Huang L, Wu J, Hong C
Neurochemical research 2023 Feb;48(2):579-590
Neurochemical research 2023 Feb;48(2):579-590
Ubiquitin-specific protease 24 promotes EV71 infection by restricting K63-linked polyubiquitination of TBK1.
Zang L, Gu J, Yang X, Yuan Y, Guo H, Zhou W, Ma J, Chen Y, Wu Y, Zheng H, Shi W
Virologica Sinica 2023 Feb;38(1):75-83
Virologica Sinica 2023 Feb;38(1):75-83
Activation of Nrf2 signaling by 4-octyl itaconate attenuates the cartilaginous endplate degeneration by inhibiting E3 ubiquitin ligase ZNF598.
Huang B, Wu H, Zheng L, Wei X, Zheng Z, Wu H, Chen J, Shan Z, Liu J, Zhao F
Osteoarthritis and cartilage 2023 Feb;31(2):213-227
Osteoarthritis and cartilage 2023 Feb;31(2):213-227
Small ankyrin 1 (sANK1) promotes docetaxel resistance in castration-resistant prostate cancer cells by enhancing oxidative phosphorylation.
Yang Y, Qin H, Ding M, Ji C, Chen W, Diao W, Yin H, Chen M, Gan W, Guo H
FEBS open bio 2023 Feb;13(2):257-269
FEBS open bio 2023 Feb;13(2):257-269
Effects of the CDC10 (Septin 7) Gene on the Proliferation and Differentiation of Bovine Intramuscular Preadipocyte and 3T3-L1 Cells.
Cheng Z, Li X, Bao S, Yamada T, Cao G, Liu J, Chen A, Tong B
Animals : an open access journal from MDPI 2023 Feb 9;13(4)
Animals : an open access journal from MDPI 2023 Feb 9;13(4)
Application of deep generative model for design of Pyrrolo[2,3-d] pyrimidine derivatives as new selective TANK binding kinase 1 (TBK1) inhibitors.
Song S, Tang H, Ran T, Fang F, Tong L, Chen H, Xie H, Lu X
European journal of medicinal chemistry 2023 Feb 5;247:115034
European journal of medicinal chemistry 2023 Feb 5;247:115034
Development of highly potent and specific AKR1C3 inhibitors to restore the chemosensitivity of drug-resistant breast cancer.
Liu Y, Chen Y, Jiang J, Chu X, Guo Q, Zhao L, Feng F, Liu W, Zhang X, He S, Yang P, Fang P, Sun H
European journal of medicinal chemistry 2023 Feb 5;247:115013
European journal of medicinal chemistry 2023 Feb 5;247:115013
Supplementation with α-ketoglutarate improved the efficacy of anti-PD1 melanoma treatment through epigenetic modulation of PD-L1.
Liu N, Zhang J, Yan M, Chen L, Wu J, Tao Q, Yan B, Chen X, Peng C
Cell death & disease 2023 Feb 28;14(2):170
Cell death & disease 2023 Feb 28;14(2):170
Arthrocolins Synergizing with Fluconazole Inhibit Fluconazole-Resistant Candida albicans by Increasing Riboflavin Metabolism and Causing Mitochondrial Dysfunction and Autophagy.
Wu Z, Wu QF, Yuan WL, Chen YH, Hu D, Deng DY, Zhang LL, Niu XM
Microbiology spectrum 2023 Feb 27;11(2):e0405122
Microbiology spectrum 2023 Feb 27;11(2):e0405122
ARL9 is upregulated and serves as a biomarker for a poor prognosis in colon adenocarcinoma.
Yang HD, Jin XX, Gu BB, Yu-Zhang, Li D, Yan LL
BMC gastroenterology 2023 Feb 23;23(1):48
BMC gastroenterology 2023 Feb 23;23(1):48
PAK2 is essential for chromosome alignment in metaphase I oocytes.
Zeng J, Wang S, Gao M, Lu D, Song S, Chen D, Fan W, Xu Z, Zhang Z, Sun X
Cell death & disease 2023 Feb 22;14(2):150
Cell death & disease 2023 Feb 22;14(2):150
RBX1 regulates PKM alternative splicing to facilitate anaplastic thyroid carcinoma metastasis and aerobic glycolysis by destroying the SMAR1/HDAC6 complex.
Xu D, Yu J, Yang Y, Du Y, Lu H, Zhang S, Feng Q, Yu Y, Hao L, Shao J, Chen L
Cell & bioscience 2023 Feb 21;13(1):36
Cell & bioscience 2023 Feb 21;13(1):36
Differential effects of the LncRNA RNF157-AS1 on epithelial ovarian cancer cells through suppression of DIRAS3- and ULK1-mediated autophagy.
Xu P, Xu S, Pan H, Dai C, Xu Y, Wang L, Cong Y, Zhang H, Cao J, Ge L, Jia X
Cell death & disease 2023 Feb 20;14(2):140
Cell death & disease 2023 Feb 20;14(2):140
Nanodrug rescues liver fibrosis via synergistic therapy with H(2)O(2) depletion and Saikosaponin b1 sustained release.
Dong H, Han X, Hao M, Yang Q, Lyu Q, Tang D, Shen Z, Wang K, Kuang H, Cao G, Peng M, Shao M
Communications biology 2023 Feb 16;6(1):184
Communications biology 2023 Feb 16;6(1):184
N(6)-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis.
Chen B, Huang Y, He S, Yu P, Wu L, Peng H
Cell chemical biology 2023 Feb 16;30(2):144-158.e10
Cell chemical biology 2023 Feb 16;30(2):144-158.e10
Exendin-4 alleviates myocardial ischemia reperfusion injury by enhancing autophagy through promoting nuclear translocation of TFEB.
He W, Tong G, Fan H, Zhen C, Zeng L, Xue L, Chen J, Sun Z, He P
Experimental cell research 2023 Feb 15;423(2):113469
Experimental cell research 2023 Feb 15;423(2):113469
Development of a series of quinazoline-2,5-diamine derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors.
Shi H, Tang H, Li Y, Chen D, Liu T, Chen Y, Wang X, Chen L, Wang Y, Xie H, Xiong B
European journal of medicinal chemistry 2023 Feb 15;248:115064
European journal of medicinal chemistry 2023 Feb 15;248:115064
Rationally designed donepezil-based hydroxamates modulate Sig-1R and HDAC isoforms to exert anti-glioblastoma effects.
Nepali K, Wu AC, Lo WL, Chopra B, Lai MJ, Chuang JY, Liou JP
European journal of medicinal chemistry 2023 Feb 15;248:115054
European journal of medicinal chemistry 2023 Feb 15;248:115054
Sulforaphane attenuates microglia-mediated neuronal damage by down-regulating the ROS/autophagy/NLRP3 signal axis in fibrillar Aβ-activated microglia.
Yang Y, Zhang J, Yang C, Dong B, Fu Y, Wang Y, Gong M, Liu T, Qiu P, Xie W, Lü T
Brain research 2023 Feb 15;1801:148206
Brain research 2023 Feb 15;1801:148206
MAD2B Blunts Chronic Unpredictable Stress and Corticosterone Stimulation-Induced Depression-Like Behaviors in Mice.
Wang XL, Miao C, Su Y, Zhang C, Meng X
The international journal of neuropsychopharmacology 2023 Feb 14;26(2):137-148
The international journal of neuropsychopharmacology 2023 Feb 14;26(2):137-148
Luteoloside Induces G0/G1 Phase Arrest of Neuroblastoma Cells by Targeting p38 MAPK.
He Y, Luo M, Lei S, Zeng Z, Chen T, Wu Y, Wang D, Wang L, Wang L
Molecules (Basel, Switzerland) 2023 Feb 12;28(4)
Molecules (Basel, Switzerland) 2023 Feb 12;28(4)
Deciphering the underlying wound healing mechanisms of Streptocaulon juventas (Lour.) Merr. by integrating network pharmacology, transcriptomics, and experimental validation.
Li Y, Zang J, Wang X, Feng X, Qiu F
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115890
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115890
Bumetanide Rescues Aquaporin-4 Depolarization via Suppressing β-Dystroglycan Cleavage and Provides Neuroprotection in Rat Retinal Ischemia-Reperfusion Injury.
Chen C, Fan P, Zhang L, Xue K, Hu J, Huang J, Lu W, Xu J, Xu S, Qiu G, Ran J, Gan S
Neuroscience 2023 Feb 1;510:95-108
Neuroscience 2023 Feb 1;510:95-108
SIRT3-dependent mitochondrial redox homeostasis mitigates CHK1 inhibition combined with gemcitabine treatment induced cardiotoxicity in hiPSC-CMs and mice.
Chen JW, Shan TK, Wei TW, Jiang QQ, Du C, Gu LF, Yang TT, Zhou LH, Wang SB, Bao YL, Wang H, Ji Y, Xie LP, Gu AH, Sun CQ, Wang QM, Wang LS
Archives of toxicology 2023 Dec;97(12):3209-3226
Archives of toxicology 2023 Dec;97(12):3209-3226
FSIP1 enhances the therapeutic sensitivity to CDK4/6 inhibitors in triple-negative breast cancer patients by activating the Nanog pathway.
Chen G, Sun L, Gu X, Ai L, Yang J, Zhang Z, Hou P, Wang Y, Ou X, Jiang X, Qiao X, Ma Q, Niu N, Xue J, Zhang H, Yang Y, Liu C
Science China. Life sciences 2023 Dec;66(12):2805-2817
Science China. Life sciences 2023 Dec;66(12):2805-2817
Hawthorn leaves flavonoids attenuate cardiac remodeling induced by simulated microgravity.
Liu T, Ma Y, Zhao H, Wang P, Niu Y, Hu Y, Shen X, Zhang M, Yan B, Yu J
Pharmaceutical biology 2023 Dec;61(1):683-695
Pharmaceutical biology 2023 Dec;61(1):683-695
PPARβ/δ activation protects against hepatic ischaemia-reperfusion injury.
Qian B, Wang C, Li X, Ma P, Dong L, Shen B, Wu H, Li N, Kang K, Ma Y
Liver international : official journal of the International Association for the Study of the Liver 2023 Dec;43(12):2808-2823
Liver international : official journal of the International Association for the Study of the Liver 2023 Dec;43(12):2808-2823
The Lnc-RNA APPAT Suppresses Human Aortic Smooth Muscle Cell Proliferation and Migration by Interacting With MiR-647 and FGF5 in Atherosclerosis.
Meng F, Han L, Liang Q, Lu S, Huang Y, Liu J
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 2023 Dec;30(6):937-950
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 2023 Dec;30(6):937-950
A novel homozygous Y140X mutation of ISG15 causes diverse type I interferonopathies in sibling patients with cutaneous lesions or recurrent parenchymal pneumonia.
Xu Q, Li W, Zhao Q, Zhao L, Lv G, Sun G, Gao Y, Ding Y, Zhang Z, Zhou L, Chen Y, Tang X, Zhu J, Zhao X, An Y
Clinical immunology (Orlando, Fla.) 2023 Dec;257:109844
Clinical immunology (Orlando, Fla.) 2023 Dec;257:109844
CoCl(2) -triggered pseudohypoxic stress induces proteasomal degradation of SIRT4 via polyubiquitination of lysines K78 and K299.
Hampel N, Georgy J, Mehrabipour M, Lang A, Lehmkuhl I, Scheller J, Ahmadian MR, Floss DM, Piekorz RP
FEBS open bio 2023 Dec;13(12):2187-2199
FEBS open bio 2023 Dec;13(12):2187-2199
Diabetic and nondiabetic BMSC-derived exosomes affect bone regeneration via regulating miR-17-5p/SMAD7 axis.
Li Z, Zhang B, Shang J, Wang Y, Jia L, She X, Xu X, Zhang D, Guo J, Zhang F
International immunopharmacology 2023 Dec;125(Pt B):111190
International immunopharmacology 2023 Dec;125(Pt B):111190
Bone Marrow-Derived GCA(+) Immune Cells Drive Alzheimer's Disease Progression.
Zhou R, Wang L, Chen L, Feng X, Zhou R, Xiang P, Wen J, Huang Y, Zhou H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2303402
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2303402
Inhibition of CK2/ING4 Pathway Facilitates Non-Small Cell Lung Cancer Immunotherapy.
Gou Q, Chen H, Chen M, Shi J, Jin J, Liu Q, Hou Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304068
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304068
Colchicine Attenuates Microvascular Obstruction after Myocardial Ischemia-Reperfusion Injury by Inhibiting the Proliferation of Neutrophil in Bone Marrow.
Tan Y, Bao X, Li Y, Song G, Lu H, Sun X, Gu R, Kang L, Xu B
Cardiovascular drugs and therapy 2023 Dec 8;
Cardiovascular drugs and therapy 2023 Dec 8;
SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation.
Zhang W, Dai J, Hou G, Liu H, Zheng S, Wang X, Lin Q, Zhang Y, Lu M, Gong Y, Xiang Z, Yu Y, Hu Y
Molecular cell 2023 Dec 7;83(23):4352-4369.e8
Molecular cell 2023 Dec 7;83(23):4352-4369.e8
FT895 Impairs Mitochondrial Function in Malignant Peripheral Nerve Sheath Tumor Cells.
Huang PY, Shih IA, Liao YC, You HL, Lee MJ
International journal of molecular sciences 2023 Dec 24;25(1)
International journal of molecular sciences 2023 Dec 24;25(1)
Aberrant epithelial cell interaction promotes esophageal squamous-cell carcinoma development and progression.
Chen L, Zhu S, Liu T, Zhao X, Xiang T, Hu X, Wu C, Lin D
Signal transduction and targeted therapy 2023 Dec 15;8(1):453
Signal transduction and targeted therapy 2023 Dec 15;8(1):453
A positive feedback circuit driven by m(6)A-modified circular RNA facilitates colorectal cancer liver metastasis.
Zeng K, Peng J, Xing Y, Zhang L, Zeng P, Li W, Zhang W, Pan Z, Zhou C, Lin J
Molecular cancer 2023 Dec 13;22(1):202
Molecular cancer 2023 Dec 13;22(1):202
TMEM44-AS1 promotes esophageal squamous cell carcinoma progression by regulating the IGF2BP2-GPX4 axis in modulating ferroptosis.
Yang R, Wan J, Ma L, Zhou F, Yang Z, Li Z, Zhang M, Ming L
Cell death discovery 2023 Dec 1;9(1):431
Cell death discovery 2023 Dec 1;9(1):431
Squalene epoxidase promotes breast cancer progression by regulating CCNB1 protein stability.
Tuluhong D, Gao H, Li X, Wang L, Zhu Y, Xu C, Wang J, Li H, Li Q, Wang S
Experimental cell research 2023 Dec 1;433(1):113805
Experimental cell research 2023 Dec 1;433(1):113805
Ubiquitin-Like Protein FAT10 Promote Colorectal Cancer Progression by Affecting the Ubiquitination of Capn4.
Cheng F, Yuan L, Wu Z, Li X, Xia W, Huang Z, Li Z, Mao S, Shen W
Digestive diseases and sciences 2023 Aug;68(8):3312-3323
Digestive diseases and sciences 2023 Aug;68(8):3312-3323
OGG1 aggravates renal ischemia-reperfusion injury by repressing PINK1-mediated mitophagy.
Zhao F, Zhu J, Zhang M, Luo Y, Li Y, Shi L, Huang J, Shadekejiang H, Dong S, Wu X
Cell proliferation 2023 Aug;56(8):e13418
Cell proliferation 2023 Aug;56(8):e13418
CCE and EODF as two distinct non-shivering thermogenesis models inducing weight loss.
Xu T, Wang J, Shi H, Wei X, Zhang H, Ji Y, Lu S, Yan Y, Yu X, Luo X, Wang H
Pflugers Archiv : European journal of physiology 2023 Aug;475(8):961-974
Pflugers Archiv : European journal of physiology 2023 Aug;475(8):961-974
CNTN1 in the Nucleus Accumbens is Involved in Methamphetamine-Induced Conditioned Place Preference in Mice.
Zhang L, Zeng Z, Lu X, Li M, Yao J, Zou G, Chen Z, Li Q, Li C, Li F
Neurotoxicity research 2023 Aug;41(4):324-337
Neurotoxicity research 2023 Aug;41(4):324-337
Sanggenon C inhibits cell proliferation and induces apoptosis by regulating the MIB1/DAPK1 axis in glioblastoma.
Chang H, Hou J, Shao Y, Xu M, Weng X, Du Y, Shi J, Zhang L, Cui H
MedComm 2023 Aug;4(4):e281
MedComm 2023 Aug;4(4):e281
Role of FBXL5 in redox homeostasis and spindle assembly during oocyte maturation in mice.
Wang S, Wu X, Wang H, Song S, Hu Y, Guo Y, Chang S, Cheng Y, Zeng S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Aug;37(8):e23080
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Aug;37(8):e23080
Exogenous hydrogen sulfide alleviates hepatic endoplasmic reticulum stress via SIRT1/FoxO1/PCSK9 pathway in NAFLD.
Cui X, Yao M, Feng Y, Li C, Li Y, Guo D, He S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Aug;37(8):e23027
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Aug;37(8):e23027
Dynamic Landscapes of tRNA Transcriptomes and Translatomes in Diverse Mouse Tissues.
Yu P, Zhou S, Gao Y, Liang Y, Guo W, Wang DO, Ding S, Lin S, Wang J, Cun Y
Genomics, proteomics & bioinformatics 2023 Aug;21(4):834-849
Genomics, proteomics & bioinformatics 2023 Aug;21(4):834-849
Three-in-One Oncolytic Adenovirus System Initiates a Synergetic Photodynamic Immunotherapy in Immune-Suppressive Cholangiocarcinoma.
Wang J, Zhu Y, Chen Y, Huang Y, Guo Q, Wang Y, Chen A, Zhou Y, Xu L, Wang L, Zou X, Li X
Small (Weinheim an der Bergstrasse, Germany) 2023 Aug;19(34):e2207668
Small (Weinheim an der Bergstrasse, Germany) 2023 Aug;19(34):e2207668
A new class of potent liver injury protective compounds: Structural elucidation, total synthesis and bioactivity study.
Ji K, Liu W, Yin W, Kong X, Xu H, Lai ZW, Li JY, Yue JM
Acta pharmaceutica Sinica. B 2023 Aug;13(8):3414-3424
Acta pharmaceutica Sinica. B 2023 Aug;13(8):3414-3424
PPARγ agonist inhibits c-Myc-mediated colorectal cancer tumor immune escape.
Xu L, Che S, Chen H, Liu Q, Shi J, Jin J, Hou Y
Journal of cellular biochemistry 2023 Aug;124(8):1145-1154
Journal of cellular biochemistry 2023 Aug;124(8):1145-1154
Augmenter of liver regeneration promotes drug resistance of acute lymphoblastic leukemia through the alteration of mitochondrial functions and the inhibition of the mitochondrial apoptosis pathway.
Zhou J, Zhou Y, Yuan S, Li Y, Xiao W, Zhang P, Lou S, Shen Y
European journal of haematology 2023 Aug;111(2):279-292
European journal of haematology 2023 Aug;111(2):279-292
Identification and Screening of Potential ACE2 Activating Peptides from Soybean Protein Isolate Hydrolysate against Ang II-Induced Endothelial Dysfunction.
Zhou M, Song T, Li W, Huang M, Zheng L, Zhao M
Journal of agricultural and food chemistry 2023 Aug 9;71(31):11957-11969
Journal of agricultural and food chemistry 2023 Aug 9;71(31):11957-11969
Intermittent dietary methionine deprivation facilitates tumoral ferroptosis and synergizes with checkpoint blockade.
Xue Y, Lu F, Chang Z, Li J, Gao Y, Zhou J, Luo Y, Lai Y, Cao S, Li X, Zhou Y, Li Y, Tan Z, Cheng X, Li X, Chen J, Wang W
Nature communications 2023 Aug 8;14(1):4758
Nature communications 2023 Aug 8;14(1):4758
Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8(+) T cell exhaustion via TRIM14-IFN-β axis.
Ma X, Wang Q, Sun C, Agarwal I, Wu H, Chen J, Zhao C, Qi G, Teng Q, Yuan C, Yan S, Peng J, Li R, Song K, Zhang Q, Kong B
Cell reports 2023 Aug 29;42(8):112944
Cell reports 2023 Aug 29;42(8):112944
Smooth muscle liver kinase B1 inhibits foam cell formation and atherosclerosis via direct phosphorylation and activation of SIRT6.
Deng Q, Li H, Yue X, Guo C, Sun Y, Ma C, Gao J, Wu Y, Du B, Yang J, Zhang C, Zhang W
Cell death & disease 2023 Aug 22;14(8):542
Cell death & disease 2023 Aug 22;14(8):542
Neuroprotection of β-caryophyllene against cerebral ischemia/reperfusion injury by inhibiting P38 MAPK/NLRP3 signaling pathway.
Zhao H, Deng L, Chen S, Wang X, Dong Z
Neuroreport 2023 Aug 2;34(12):617-623
Neuroreport 2023 Aug 2;34(12):617-623
HOXA11 promotes lymphatic metastasis of gastric cancer via transcriptional activation of TGFβ1.
Li Z, Lu T, Chen Z, Yu X, Wang L, Shen G, Huang H, Li Z, Ren Y, Guo W, Hu Y
iScience 2023 Aug 18;26(8):107346
iScience 2023 Aug 18;26(8):107346
GM-CSF receptor/SYK/JNK/FOXO1/CD11c signaling promotes atherosclerosis.
Tsukui D, Kimura Y, Kono H
iScience 2023 Aug 18;26(8):107293
iScience 2023 Aug 18;26(8):107293
Characterization of the Effects of Host p53 and Fos on Gallid Alpha Herpesvirus 1 Replication.
Liu Z, Cui L, Li X, Xu L, Zhang Y, Han Z, Liu S, Li H
Genes 2023 Aug 12;14(8)
Genes 2023 Aug 12;14(8)
Different levels of autophagy induced by transient serum starvation regulate metabolism and differentiation of porcine skeletal muscle satellite cells.
Wang Y, Gao J, Fan B, Hu Y, Yang Y, Wu Y, Li F, Ju H
Scientific reports 2023 Aug 12;13(1):13153
Scientific reports 2023 Aug 12;13(1):13153
CRISPR screen identifies GATAD1 as a synthetic lethal target with CDK4/6 inhibitors in estrogen receptor-positive breast cancer.
Liu W, Zhang R, Yu X, Zhang Y, Kang T, Liao D
Medical oncology (Northwood, London, England) 2023 Aug 11;40(9):267
Medical oncology (Northwood, London, England) 2023 Aug 11;40(9):267
Saponin extract from Achyranthes bidentata Blume alleviates disuse-induced muscle atrophy through PI3K/Akt signaling pathway.
Shi Y, Zhang ZW, Du MM, Wu J, Li JX
Journal of ethnopharmacology 2023 Aug 10;312:116458
Journal of ethnopharmacology 2023 Aug 10;312:116458
Houpo paiqi mixture promotes intestinal motility in constipated rats by modulating gut microbiota and activating 5-HT-cAMP-PKA signal pathway.
Wang R, Lu X, Zhao L, Zhang W, Zhang S
Journal of applied microbiology 2023 Aug 1;134(8)
Journal of applied microbiology 2023 Aug 1;134(8)
Chemokine receptor CXCR7 activates Aurora Kinase A and promotes neuroendocrine prostate cancer growth.
Gritsina G, Fong KW, Lu X, Lin Z, Xie W, Agarwal S, Lin D, Schiltz GE, Beltran H, Corey E, Morrissey C, Wang Y, Zhao JC, Hussain M, Yu J
The Journal of clinical investigation 2023 Aug 1;133(15)
The Journal of clinical investigation 2023 Aug 1;133(15)
A cell-autonomous mechanism regulates BCAA catabolism in white adipocytes and systemic metabolic balance.
Aguillard AM, Tzeng J, Ferrer I, Tam BT, Lorenzo DN
bioRxiv : the preprint server for biology 2023 Aug 1;
bioRxiv : the preprint server for biology 2023 Aug 1;
Lanthanum Chloride Induces Axon Abnormality Through LKB1-MARK2 and LKB1-STK25-GM130 Signaling Pathways.
Song Z, Mao H, Liu J, Sun W, Wu S, Lu X, Jin C, Yang J
Cellular and molecular neurobiology 2023 Apr;43(3):1181-1196
Cellular and molecular neurobiology 2023 Apr;43(3):1181-1196
Kaempferol promotes melanogenesis and reduces oxidative stress in PIG1 normal human skin melanocytes.
Xie Y, Mei X, Shi W
Journal of cellular and molecular medicine 2023 Apr;27(7):982-990
Journal of cellular and molecular medicine 2023 Apr;27(7):982-990
Geranylgeranylacetone-induced heat shock protein70 expression reduces retinal ischemia-reperfusion injury through PI3K/AKT/mTOR signaling.
Zhang L, Xue K, Fan P, Chen C, Hu J, Huang J, Lu W, Xu J, Xu S, Ran J, Zhu S, Gan S
Experimental eye research 2023 Apr;229:109416
Experimental eye research 2023 Apr;229:109416
Mice with the Rab10 T73V mutation exhibit anxiety-like behavior and alteration of neuronal functions in the striatum.
Zhang J, Li J, You P, Jiang H, Liu Y, Han D, Liu M, Yu H, Su B
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166641
Biochimica et biophysica acta. Molecular basis of disease 2023 Apr;1869(4):166641
Growth differentiation factor 15 is dispensable for acetaminophen-induced liver injury in mice.
Jiang P, Liu Z, Fang T, Zhang Z, Zhang Y, Wang D, Little PJ, Xu S, Weng J
Basic & clinical pharmacology & toxicology 2023 Apr;132(4):343-353
Basic & clinical pharmacology & toxicology 2023 Apr;132(4):343-353
Novel Self-Assembled Multifunctional Nanoprobes for Second-Near-Infrared-Fluorescence-Image-Guided Breast Cancer Surgery and Enhanced Radiotherapy Efficacy.
Zhang YQ, Liu WL, Luo XJ, Shi JP, Zeng YZ, Chen WL, Huang WH, Zhu YY, Gao WL, Li RH, Ming ZH, Zhang LX, Yang RQ, Wang JZ, Zhang GJ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(10):e2205294
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(10):e2205294
Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting.
Zhao Y, Li S, Chen Y, Wang Y, Wei Y, Zhou T, Zhang Y, Yang Y, Chen L, Liu Y, Hu C, Zhou B, Ding Q
Molecular cell 2023 Apr 6;83(7):1093-1108.e8
Molecular cell 2023 Apr 6;83(7):1093-1108.e8
Analysis and verification of the circRNA regulatory network RNO_CIRCpedia_ 4214/RNO-miR-667-5p/Msr1 axis as a potential ceRNA promoting macrophage M2-like polarization in spinal cord injury.
Cao J, Pan C, Zhang J, Chen Q, Li T, He D, Cheng X
BMC genomics 2023 Apr 5;24(1):181
BMC genomics 2023 Apr 5;24(1):181
Ligation to Scavenging Strategy Enables On-Demand Termination of Targeted Protein Degradation.
Jin Y, Fan J, Wang R, Wang X, Li N, You Q, Jiang Z
Journal of the American Chemical Society 2023 Apr 5;145(13):7218-7229
Journal of the American Chemical Society 2023 Apr 5;145(13):7218-7229
Downregulation of AC092894.1 promotes oxaliplatin resistance in colorectal cancer via the USP3/AR/RASGRP3 axis.
Zheng Z, Wu M, Li H, Xu W, Yang M, Pan K, Ni Y, Jiang T, Zheng H, Jin X, Zhang Y, Ding L, Fu J
BMC medicine 2023 Apr 3;21(1):132
BMC medicine 2023 Apr 3;21(1):132
Allograft inflammatory factor 1 is a potential diagnostic, immunological, and prognostic biomarker in pan-cancer.
Liu X, Zhang D, Hu J, Xu S, Xu C, Shen Y
Aging 2023 Apr 3;15(7):2582-2609
Aging 2023 Apr 3;15(7):2582-2609
Recognition of an Ala-rich C-degron by the E3 ligase Pirh2.
Wang X, Li Y, Yan X, Yang Q, Zhang B, Zhang Y, Yuan X, Jiang C, Chen D, Liu Q, Liu T, Mi W, Yu Y, Dong C
Nature communications 2023 Apr 29;14(1):2474
Nature communications 2023 Apr 29;14(1):2474
Enhanced E6AP-mediated ubiquitination of ENO1 via LINC00663 contributes to radiosensitivity of breast cancer by regulating mitochondrial homeostasis.
Ma J, Zhu J, Li J, Liu J, Kang X, Yu J
Cancer letters 2023 Apr 28;560:216118
Cancer letters 2023 Apr 28;560:216118
Rift Valley Fever Virus Nucleoprotein Triggers Autophagy to Dampen Antiviral Innate Immune Responses.
Zhu X, Guan Z, Fang Y, Zhang Y, Guan Z, Li S, Peng K
Journal of virology 2023 Apr 27;97(4):e0181422
Journal of virology 2023 Apr 27;97(4):e0181422
Strategy To Assess Zoonotic Potential Reveals Low Risk Posed by SARS-Related Coronaviruses from Bat and Pangolin.
Yang Y, Shen XR, Zhang YL, Jiang RD, Wang X, Guan ZQ, Li Q, Yao YL, Gong QC, Geng R, Wang Q, Zhu Y, Luo JY, Shi ZL, Zhang HL, Peng K, Zhou P
mBio 2023 Apr 25;14(2):e0328522
mBio 2023 Apr 25;14(2):e0328522
Progesterone prevents HGSOC by promoting precancerous cell pyroptosis via inducing fibroblast paracrine.
Wu N, Zhang X, Wang Z, Zhang X, Fang C, Li H, Zhu M, Wang Y, Liao Q, Chu TY, Wang J
iScience 2023 Apr 21;26(4):106523
iScience 2023 Apr 21;26(4):106523
PIMT is a novel and potent suppressor of endothelial activation.
Zhang C, Guo ZF, Liu W, Kazama K, Hu L, Sun X, Wang L, Lee H, Lu L, Yang XF, Summer R, Sun J
eLife 2023 Apr 18;12
eLife 2023 Apr 18;12
Unusually severe muscular dystrophy upon in-frame deletion of the dystrophin rod domain and lack of compensation by membrane-localized utrophin.
Gorokhova S, Schessl J, Zou Y, Yang ML, Heydemann PT, Sufit RL, Meilleur K, Donkervoort S, Medne L, Finkel RS, Bönnemann CG
Med (New York, N.Y.) 2023 Apr 14;4(4):245-251.e3
Med (New York, N.Y.) 2023 Apr 14;4(4):245-251.e3
Circular RNA hsa_circ_0007444 inhibits ovarian cancer progression through miR-23a-3p/DICER1 axis.
Zhang M, Sun Y, Xu H, Shi Y, Shen R, Teng F, Xu J, Jia X
Acta biochimica et biophysica Sinica 2023 Apr 13;55(4):574-586
Acta biochimica et biophysica Sinica 2023 Apr 13;55(4):574-586
LCRMP-1 is required for spermatogenesis and stabilises spermatid F-actin organization via the PI3K-Akt pathway.
Chang JH, Chou CH, Wu JC, Liao KM, Luo WJ, Hsu WL, Chen XR, Yu SL, Pan SH, Yang PC, Su KY
Communications biology 2023 Apr 10;6(1):389
Communications biology 2023 Apr 10;6(1):389
Non-canonical Small GTPase RBJ Promotes NSCLC Progression Through the Canonical MEK/ERK Signaling Pathway.
Wang Y, Shen X, Wang Q, Guo Z, Hu L, Dong Z, Hu W
Current pharmaceutical design 2022;28(42):3446-3455
Current pharmaceutical design 2022;28(42):3446-3455
Electroacupuncture-Regulated miR-34a-3p/PDCD6 Axis Promotes Post-Spinal Cord Injury Recovery in Both In Vitro and In Vivo Settings.
Ma L, Ma L, Yang Y, Chen T, Wang L, Deng Q
Journal of immunology research 2022;2022:9329494
Journal of immunology research 2022;2022:9329494
Protective Effects of the Wenfei Buqi Tongluo Formula on the Inflammation in Idiopathic Pulmonary Fibrosis through Inhibiting the TLR4/MyD88/NF-κB Pathway.
Song S, Wang J, Liu G, Ding L, Li Y, Qi H, Wei L, Zhao J, Chen T, Zhao M, Wang Z, Yang Y, Zhao D, Li X, Wang Z
BioMed research international 2022;2022:8752325
BioMed research international 2022;2022:8752325
ATF4/MYC Regulates MTHFD2 to Promote NSCLC Progression by Mediating Redox Homeostasis.
Gao Y, Feng L, Zhang L, Geng J, Zhang E
Disease markers 2022;2022:7527996
Disease markers 2022;2022:7527996
Alarm Signal S100-Related Signature Is Correlated with Tumor Microenvironment and Predicts Prognosis in Glioma.
Wang LJ, Lv P, Lou Y
Disease markers 2022;2022:4968555
Disease markers 2022;2022:4968555
Predicting the Immune Microenvironment and Prognosis with a NETosis-Related lncRNA Signature in Head and Neck Squamous Cell Carcinoma.
He X, Xiao Y, Liu S, Deng R, Li Z, Zhu X
BioMed research international 2022;2022:3191474
BioMed research international 2022;2022:3191474
Water Treadmill Training Ameliorates Neurite Outgrowth Inhibition Associated with NGR/RhoA/ROCK by Inhibiting Astrocyte Activation following Spinal Cord Injury.
Ying X, Yu X, Zhu J, Li X, Zheng Y, Xie Q, Wu Q, Li S, Yue J, Zhou Y, Zhou K, Tu W, Jiang S
Oxidative medicine and cellular longevity 2022;2022:1724362
Oxidative medicine and cellular longevity 2022;2022:1724362
Corilagin Restrains NLRP3 Inflammasome Activation and Pyroptosis through the ROS/TXNIP/NLRP3 Pathway to Prevent Inflammation.
Luo T, Zhou X, Qin M, Lin Y, Lin J, Chen G, Liu A, Ouyang D, Chen D, Pan H
Oxidative medicine and cellular longevity 2022;2022:1652244
Oxidative medicine and cellular longevity 2022;2022:1652244
Suppressing MDSC Infiltration in Tumor Microenvironment Serves as an Option for Treating Ovarian Cancer Metastasis.
Li Y, Zhang Q, Wu M, Zhang P, Huang L, Ai X, Yang Z, Shen Q, Wang Y, Wang P, Zhou S, He ML
International journal of biological sciences 2022;18(9):3697-3713
International journal of biological sciences 2022;18(9):3697-3713
CIRBP-OGFR axis safeguards against cardiomyocyte apoptosis and cardiotoxicity induced by chemotherapy.
Liu C, Cheng X, Xing J, Li J, Li Z, Jian D, Wang Y, Wang S, Li R, Zhang W, Shao D, Ma X, Chen X, Shen J, Shi C, Guo Z, Wang W, Fan T, Liu L, Tang H
International journal of biological sciences 2022;18(7):2882-2897
International journal of biological sciences 2022;18(7):2882-2897
Melatonin reverses tumor necrosis factor-alpha-induced metabolic disturbance of human nucleus pulposus cells via MTNR1B/Gαi2/YAP signaling.
Qiu X, Liang T, Wu Z, Zhu Y, Gao W, Gao B, Qiu J, Wang X, Chen T, Deng Z, Li P, Chen Y, Zhou H, Peng Y, Xu C, Su P, Liang A, Huang D
International journal of biological sciences 2022;18(5):2202-2219
International journal of biological sciences 2022;18(5):2202-2219
MAD2B promotes podocyte injury through regulating Numb-dependent Notch 1 pathway in diabetic nephropathy.
Li MR, Lei CT, Tang H, Yin XJ, Hao Z, Qiu Y, Xie YR, Zeng JY, Su H, Zhang C
International journal of biological sciences 2022;18(5):1896-1911
International journal of biological sciences 2022;18(5):1896-1911
Identification of potential key circular RNAs related to cognitive impairment after chronic constriction injury of the sciatic nerve.
Liu C, Gao R, Tang Y, Chen H, Zhang X, Sun Y, Zhao Q, Lv P, Wang H, Ye-Lehmann S, Liu J, Chen C
Frontiers in neuroscience 2022;16:925300
Frontiers in neuroscience 2022;16:925300
Antidepressant-Like Effect and Mechanism of Ginsenoside Rd on Rodent Models of Depression.
Li Y, Wang ML, Zhang B, Fan XX, Tang Q, Yu X, Li LN, Fan AR, Chang HS, Zhang LZ
Drug design, development and therapy 2022;16:843-861
Drug design, development and therapy 2022;16:843-861
Laparotomy-Induced Peripheral Inflammation Activates NR2B Receptors on the Brain Mast Cells and Results in Neuroinflammation in a Vagus Nerve-Dependent Manner.
Yang J, Dong HQ, Liu YH, Ji MH, Zhang X, Dai HY, Sun ZC, Liu L, Zhou J, Sha HH, Qian YN, Li QG, Yao H, Li NN
Frontiers in cellular neuroscience 2022;16:771156
Frontiers in cellular neuroscience 2022;16:771156
Carbon Monoxide-Releasing Molecule-3 Enhances Osteogenic Differentiation of Rat Bone Marrow Mesenchymal Stem Cells via miR-195-5p/Wnt3a Pathway.
Li J, Han Q, Chen H, Liu T, Song J, Hou M, Wei L, Song H
Drug design, development and therapy 2022;16:2101-2117
Drug design, development and therapy 2022;16:2101-2117
The Therapeutic Effect and the Possible Mechanism of C-Phycocyanin in Lipopolysaccharide and Seawater-Induced Acute Lung Injury.
Zhang L, Kong D, Huang J, Wang Q, Shao L
Drug design, development and therapy 2022;16:1025-1040
Drug design, development and therapy 2022;16:1025-1040
Nedd4-2 Haploinsufficiency in Mice Impairs the Ubiquitination of Rer1 and Increases the Susceptibility to Endoplasmic Reticulum Stress and Seizures.
Liu X, Zhang L, Zhang H, Liang X, Zhang B, Tu J, Zhao Y
Frontiers in molecular neuroscience 2022;15:919718
Frontiers in molecular neuroscience 2022;15:919718
FMNL3 is Overexpressed in Tumor Tissues and Predicts an Immuno-Hot Phenotype in Pancreatic Cancer.
Zhang Q, Nie H, Pan J, Xu H, Zhan Q
International journal of general medicine 2022;15:8285-8298
International journal of general medicine 2022;15:8285-8298
The Pathogenic Mechanism of the ATP2C1 p.Ala109_Gln120del Mutation in Hailey-Hailey Disease.
Li P, Qi J, Zhou B, Ding T, Long J, Xiao H
Clinical, cosmetic and investigational dermatology 2022;15:2169-2175
Clinical, cosmetic and investigational dermatology 2022;15:2169-2175
DNA 6mA Demethylase ALKBH1 Orchestrates Fatty Acid Metabolism and Suppresses Diet-Induced Hepatic Steatosis.
Luo L, Liu Y, Nizigiyimana P, Ye M, Xiao Y, Guo Q, Su T, Luo X, Huang Y, Zhou H
Cellular and molecular gastroenterology and hepatology 2022;14(6):1213-1233
Cellular and molecular gastroenterology and hepatology 2022;14(6):1213-1233
Porphyromonas gingivalis lipopolysaccharide induced RIPK3/MLKL-mediated necroptosis of oral epithelial cells and the further regulation in macrophage activation.
Geng F, Liu J, Yin C, Zhang S, Pan Y, Sun H
Journal of oral microbiology 2022;14(1):2041790
Journal of oral microbiology 2022;14(1):2041790
Confinement induces oxidative damage and synaptic dysfunction in mice.
Li N, Wang H, Xin S, Min R, Zhang Y, Deng Y
Frontiers in physiology 2022;13:999574
Frontiers in physiology 2022;13:999574
A pyroptosis-related gene model and its correlation with the microenvironment of lung adenocarcinoma: A bioinformatics analysis and experimental verification.
Dong Y, Yi L, Song Q, Yao Y
Frontiers in genetics 2022;13:997319
Frontiers in genetics 2022;13:997319
Critical role of guanylate binding protein 5 in tumor immune microenvironment and predictive value of immunotherapy response.
Li X, Song D, Su S, He X, Cao F, Yang C, Li K, Huang S, Li C, Wang C, Zhang A, Pang P, Zheng Y
Frontiers in genetics 2022;13:984615
Frontiers in genetics 2022;13:984615
Honokiol improves depression-like behaviors in rats by HIF-1α- VEGF signaling pathway activation.
Fan XX, Sun WY, Li Y, Tang Q, Li LN, Yu X, Wang SY, Fan AR, Xu XQ, Chang HS
Frontiers in pharmacology 2022;13:968124
Frontiers in pharmacology 2022;13:968124
Shenkang injection improves chronic kidney disease by inhibiting multiple renin-angiotensin system genes by blocking the Wnt/β-catenin signalling pathway.
Wang YN, Liu HJ, Ren LL, Suo P, Zou L, Zhang YM, Yu XY, Zhao YY
Frontiers in pharmacology 2022;13:964370
Frontiers in pharmacology 2022;13:964370
Inhibition of HDAC6 With CAY10603 Ameliorates Diabetic Kidney Disease by Suppressing NLRP3 Inflammasome.
Hou Q, Kan S, Wang Z, Shi J, Zeng C, Yang D, Jiang S, Liu Z
Frontiers in pharmacology 2022;13:938391
Frontiers in pharmacology 2022;13:938391
Hypoxic Training Ameliorates Skeletal Muscle Microcirculation Vascular Function in a Sirt3-Dependent Manner.
Ma C, Zhao Y, Ding X, Gao B
Frontiers in physiology 2022;13:921763
Frontiers in physiology 2022;13:921763
Clostridium butyricum Protects Against Pancreatic and Intestinal Injury After Severe Acute Pancreatitis via Downregulation of MMP9.
Yan Q, Jia L, Wen B, Wu Y, Zeng Y, Wang Q
Frontiers in pharmacology 2022;13:919010
Frontiers in pharmacology 2022;13:919010
Artemisinin relieves myocardial ischemia-reperfusion injury via modulating miR-29b-3p and hemicentin 1.
Han J, Zhang Z, Zhang Z, Yang S
Frontiers in pharmacology 2022;13:918966
Frontiers in pharmacology 2022;13:918966
Connexin 43 (Cx43) regulates high-glucose-induced retinal endothelial cell angiogenesis and retinal neovascularization.
Shi W, Meng Z, Luo J
Frontiers in endocrinology 2022;13:909207
Frontiers in endocrinology 2022;13:909207
EspF of Enterohemorrhagic Escherichia coli Enhances Apoptosis via Endoplasmic Reticulum Stress in Intestinal Epithelial Cells: An Isobaric Tags for Relative and Absolute Quantitation-Based Comparative Proteomic Analysis.
Wang X, Yan K, Fu M, Liang S, Zhao H, Fu C, Yang L, Song Z, Sun D, Wan C
Frontiers in microbiology 2022;13:900919
Frontiers in microbiology 2022;13:900919
Platelet-Vesicles-Encapsulated RSL-3 Enable Anti-Angiogenesis and Induce Ferroptosis to Inhibit Pancreatic Cancer Progress.
Zhang Y, Huang Z, Cheng J, Pan H, Lin T, Shen X, Chen W, Chen Q, Gu C, Mao Q, Liang Y
Frontiers in endocrinology 2022;13:865655
Frontiers in endocrinology 2022;13:865655
Theaflavin-3,3'-Digallate from Black Tea Inhibits Neointima Formation Through Suppression of the PDGFRβ Pathway in Vascular Smooth Muscle Cells.
Wu Y, Chen M, Chen Z, Shu J, Zhang L, Hu J, Yu H, Huang K, Liang M
Frontiers in pharmacology 2022;13:861319
Frontiers in pharmacology 2022;13:861319
Gentiopicroside Ameliorates Diabetic Renal Tubulointerstitial Fibrosis via Inhibiting the AT1R/CK2/NF-κB Pathway.
Xu Z, Zhang M, Wang Y, Chen R, Xu S, Sun X, Yang Y, Lin Z, Wang S, Huang H
Frontiers in pharmacology 2022;13:848915
Frontiers in pharmacology 2022;13:848915
ING4 Promotes Stemness Enrichment of Human Renal Cell Carcinoma Cells Through Inhibiting DUSP4 Expression to Activate the p38 MAPK/type I IFN-Stimulated Gene Signaling Pathway.
Tang Y, Yang X, Wang Q, Huang H, Wang Q, Jiang M, Yuan C, Huang Y, Chen Y
Frontiers in pharmacology 2022;13:845097
Frontiers in pharmacology 2022;13:845097
Identification of a De Novo Heterozygous Missense ACTB Variant in Baraitser-Winter Cerebrofrontofacial Syndrome.
Nie K, Huang J, Liu L, Lv H, Chen D, Fan W
Frontiers in genetics 2022;13:828120
Frontiers in genetics 2022;13:828120
Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKα/β-NF-κB and Keap1-Nrf2 Signalling Pathways.
Yuan Y, Hu Q, Liu L, Xie F, Yang L, Li Y, Zhang C, Chen H, Tang J, Shen X
Frontiers in pharmacology 2022;13:817596
Frontiers in pharmacology 2022;13:817596
PKC-ζ Aggravates Doxorubicin-Induced Cardiotoxicity by Inhibiting Wnt/β-Catenin Signaling.
Cao YJ, Li JY, Wang PX, Lin ZR, Yu WJ, Zhang JG, Lu J, Liu PQ
Frontiers in pharmacology 2022;13:798436
Frontiers in pharmacology 2022;13:798436
Chemerin Regulates the Proliferation and Migration of Pulmonary Arterial Smooth Muscle Cells via the ERK1/2 Signaling Pathway.
Peng L, Chen Y, Li Y, Feng P, Zheng Y, Dong Y, Yang Y, Wang R, Li A, Yan J, Shang F, Tang P, Chen D, Gao Y, Huang W
Frontiers in pharmacology 2022;13:767705
Frontiers in pharmacology 2022;13:767705
The Transcription of ZIP9 Is Associated With the Macrophage Polarization and the Pathogenesis of Hepatocellular Carcinoma.
Gou Y, Yang D, Tian T, Zhu X, Zhang R, Ren J, Tu D, Luo Y, Miao Y, Zhao H, Wang Y, Wei B
Frontiers in immunology 2022;13:725595
Frontiers in immunology 2022;13:725595
Narciclasine inhibits phospholipase A2 and regulates phospholipid metabolism to ameliorate psoriasis-like dermatitis.
Kong Y, Jiang J, Huang Y, Liu X, Jin Z, Li L, Wei F, Liu X, Yin J, Zhang Y, Tong Q, Chen H
Frontiers in immunology 2022;13:1094375
Frontiers in immunology 2022;13:1094375
SIRT6 overexpression retards renal interstitial fibrosis through targeting HIPK2 in chronic kidney disease.
Li X, Li W, Zhang Z, Wang W, Huang H
Frontiers in pharmacology 2022;13:1007168
Frontiers in pharmacology 2022;13:1007168
A novel HDAC11 inhibitor potentiates the tumoricidal effects of cordycepin against malignant peripheral nerve sheath tumor through the Hippo signaling pathway.
Huang PY, Shih IA, Liao YC, You HL, Lee MJ
American journal of cancer research 2022;12(2):873-892
American journal of cancer research 2022;12(2):873-892
GPR12 Inhibits Apoptosis in Epithelial Ovarian Cancer via the Activation of ERK1/2 Signaling.
Wang L, Yang D, Zhang Y, Jiao Y
Frontiers in oncology 2022;12:932689
Frontiers in oncology 2022;12:932689
ESR1 Regulates the Obesity- and Metabolism-Differential Gene MMAA to Inhibit the Occurrence and Development of Hepatocellular Carcinoma.
Zhang Y, Cheng J, Zhong C, Xia Q, Li Y, Chen P, Fan X, Mao Q, Lin H, Hong D
Frontiers in oncology 2022;12:899969
Frontiers in oncology 2022;12:899969
Immune Characteristics and Prognosis Analysis of the Proteasome 20S Subunit Beta 9 in Lower-Grade Gliomas.
Liu J, Yang X, Ji Q, Yang L, Li J, Long X, Ye M, Huang K, Zhu X
Frontiers in oncology 2022;12:875131
Frontiers in oncology 2022;12:875131
STAT6 Upregulates NRP1 Expression in Endothelial Cells and Promotes Angiogenesis.
Gao P, Ren G, Liang J, Liu J
Frontiers in oncology 2022;12:823377
Frontiers in oncology 2022;12:823377
DJ-1 promotes osteosarcoma progression through activating CDK4/RB/E2F1 signaling pathway.
Han Z, Wang L, Wang D, Zhang L, Bi Y, Zheng X, Liu W, Bai G, Wang Z, Wan W, Ma Y, Cai X, Liu T, Jia Q
Frontiers in oncology 2022;12:1036401
Frontiers in oncology 2022;12:1036401
Crosstalk between acetylation and the tyrosination/detyrosination cycle of α-tubulin in Alzheimer's disease.
Martínez-Hernández J, Parato J, Sharma A, Soleilhac JM, Qu X, Tein E, Sproul A, Andrieux A, Goldberg Y, Moutin MJ, Bartolini F, Peris L
Frontiers in cell and developmental biology 2022;10:926914
Frontiers in cell and developmental biology 2022;10:926914
Hyaluronic Acid Facilitates Angiogenesis of Endothelial Colony Forming Cell Combining With Mesenchymal Stem Cell via CD44/ MicroRNA-139-5p Pathway.
Luo Y, Liang F, Wan X, Liu S, Fu L, Mo J, Meng X, Mo Z
Frontiers in bioengineering and biotechnology 2022;10:794037
Frontiers in bioengineering and biotechnology 2022;10:794037
Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer.
Zhang X, Luo F, Luo S, Li L, Ren X, Lin J, Liang Y, Ma C, Ding L, Zhang D, Ye T, Lin Y, Jin B, Gao S, Ye Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Sep;9(27):e2200705
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Sep;9(27):e2200705
Macrophage derived miR-7219-3p-containing exosomes mediate fibroblast trans-differentiation by targeting SPRY1 in silicosis.
Niu Z, Wang L, Qin X, Ye Z, Xie B, Hu Y
Toxicology 2022 Sep;479:153310
Toxicology 2022 Sep;479:153310
PRSS55 is a novel potential causative gene for human male infertility.
Liu M, Jiang C, Zhang X, Zhang G, Liu M, Zheng R, Yang Y, Shen Y
Reproductive biomedicine online 2022 Sep;45(3):553-562
Reproductive biomedicine online 2022 Sep;45(3):553-562
Fatty acid-binding protein 5 aggravates pulmonary artery fibrosis in pulmonary hypertension secondary to left heart disease via activating wnt/β-catenin pathway.
Lei Q, Yu Z, Li H, Cheng J, Wang Y
Journal of advanced research 2022 Sep;40:197-206
Journal of advanced research 2022 Sep;40:197-206
Nuclear Condensation of CDYL Links Histone Crotonylation and Cystogenesis in Autosomal Dominant Polycystic Kidney Disease.
Dang L, Cao X, Zhang T, Sun Y, Tian S, Gong T, Xiong H, Cao P, Li Y, Yu S, Yang L, Zhang L, Liu T, Zhang K, Liang J, Chen Y
Journal of the American Society of Nephrology : JASN 2022 Sep;33(9):1708-1725
Journal of the American Society of Nephrology : JASN 2022 Sep;33(9):1708-1725
Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia.
Zhuang H, Ren Y, Mao C, Zhong Y, Zhang Z, Cao B, Zhang Y, Huang J, Xu G, Huang Z, Xu Y, Mao X
The Journal of biological chemistry 2022 Sep;298(9):102314
The Journal of biological chemistry 2022 Sep;298(9):102314
Cullin 4b-RING ubiquitin ligase targets IRGM1 to regulate Wnt signaling and intestinal homeostasis.
Fan Y, Huo X, Guo B, Zhang X, Yang Y, Lian J, Meng X, Shao Y, Zou Y, Guo H, Wang H, Sun G, Dou H, Wang J, Shao C, Gong Y, Hu H
Cell death and differentiation 2022 Sep;29(9):1673-1688
Cell death and differentiation 2022 Sep;29(9):1673-1688
PGM3 regulates beta-catenin activity to promote colorectal cancer cell progression.
Zhang N, Liu S, Xu J, Ning T, Xie S, Min L, Zhu S, Zhang S, Zhu S
Experimental biology and medicine (Maywood, N.J.) 2022 Sep;247(17):1518-1528
Experimental biology and medicine (Maywood, N.J.) 2022 Sep;247(17):1518-1528
Opposing reduced VPAC(1) and enhanced VPAC(2) VIP receptors in the hippocampus of the Li(2+)-pilocarpine rat model of temporal lobe epilepsy.
Serpa A, Bento M, Caulino-Rocha A, Pawlak S, Cunha-Reis D
Neurochemistry international 2022 Sep;158:105383
Neurochemistry international 2022 Sep;158:105383
Generation of cost-effective MXene@polydopamine-decorated chitosan nanofibrous wound dressing for promoting wound healing.
Li H, Dai J, Yi X, Cheng F
Biomaterials advances 2022 Sep;140:213055
Biomaterials advances 2022 Sep;140:213055
Grass Carp Reovirus triggers autophagy enhancing virus replication via the Akt/mTOR pathway.
Zhu M, Zhang Y, Pan J, Tong X, Zhang X, Hu X, Gong C
Fish & shellfish immunology 2022 Sep;128:148-156
Fish & shellfish immunology 2022 Sep;128:148-156
Improvement of anticancer effect of berberine by salt formation modifications.
Xu F, Liu M, Liao Y, Zhou Y, Zhang P, Zeng Y, Liu Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154314
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154314
Atractylenolide III from Atractylodes macrocephala Koidz promotes the activation of brown and white adipose tissue through SIRT1/PGC-1α signaling pathway.
Liu X, Huang Y, Liang X, Wu Q, Wang N, Zhou LJ, Liu WW, Ma Q, Hu B, Gao H, Cui YL, Li X, Zhao QC
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154289
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154289
Prinsepiae Nux Extract Activates NRF2 Activity and Protects UVB-Induced Damage in Keratinocyte.
Wang SH, Chen YS, Lai KH, Lu CK, Chang HS, Wu HC, Yen FL, Chen LY, Lee JC, Yen CH
Antioxidants (Basel, Switzerland) 2022 Sep 5;11(9)
Antioxidants (Basel, Switzerland) 2022 Sep 5;11(9)
Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.
Jin S, He X, Ma L, Zhuang Z, Wang Y, Lin M, Cai S, Wei L, Wang Z, Zhao Z, Wu Y, Sun L, Li C, Xie W, Zhao Y, Songyang Z, Peng K, Zhao J, Cui J
Nature communications 2022 Sep 3;13(1):5204
Nature communications 2022 Sep 3;13(1):5204
Proteomic characterization of gastric cancer response to chemotherapy and targeted therapy reveals new therapeutic strategies.
Li Y, Xu C, Wang B, Xu F, Ma F, Qu Y, Jiang D, Li K, Feng J, Tian S, Wu X, Wang Y, Liu Y, Qin Z, Liu Y, Qin J, Song Q, Zhang X, Sujie A, Huang J, Liu T, Shen K, Zhao JY, Hou Y, Ding C
Nature communications 2022 Sep 29;13(1):5723
Nature communications 2022 Sep 29;13(1):5723
HOXA5 inhibits the proliferation of extrahepatic cholangiocarcinoma cells by enhancing MXD1 expression and activating the p53 pathway.
Xiong F, Liu W, Wang X, Wu G, Wang Q, Guo T, Huang W, Wang B, Chen Y
Cell death & disease 2022 Sep 27;13(9):829
Cell death & disease 2022 Sep 27;13(9):829
PGC-1β maintains mitochondrial metabolism and restrains inflammatory gene expression.
Guak H, Sheldon RD, Beddows I, Vander Ark A, Weiland MJ, Shen H, Jones RG, St-Pierre J, Ma EH, Krawczyk CM
Scientific reports 2022 Sep 26;12(1):16028
Scientific reports 2022 Sep 26;12(1):16028
miR-182-5p attenuates Schistosoma japonicum-induced hepatic fibrosis by targeting tristetraprolin.
Zhao X, Xia Z, Wang Z, Zhou M, Qiu X, Wang C, Xu T, Fang Q, Ming Z, Dong H
Acta biochimica et biophysica Sinica 2022 Sep 25;54(10):1421-1430
Acta biochimica et biophysica Sinica 2022 Sep 25;54(10):1421-1430
Design, Synthesis, and Biological Evaluation of Androgen Receptor Degrading and Antagonizing Bifunctional Steroidal Analogs for the Treatment of Advanced Prostate Cancer.
Wang A, Luo X, Wang Y, Meng X, Lu Z, Yang Y
Journal of medicinal chemistry 2022 Sep 22;65(18):12460-12481
Journal of medicinal chemistry 2022 Sep 22;65(18):12460-12481
Intestinal Epithelial STAT6 Activation Rescues the Defective Anti-Helminth Responses Caused by Ogt Deletion.
Xiong X, Huang R, Li Z, Yang C, Wang Q, Ruan HB, Xu L
International journal of molecular sciences 2022 Sep 22;23(19)
International journal of molecular sciences 2022 Sep 22;23(19)
TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation.
Wang L, Li J, Wang Q, Ge MX, Ji J, Liu D, Wang Z, Cao Y, Zhang Y, Zhang ZR
Molecular cell 2022 Sep 15;82(18):3453-3467.e14
Molecular cell 2022 Sep 15;82(18):3453-3467.e14
Mechanism underlying the targeted regulation of the SOD1 3'UTR by the AUF1/Dicer1/miR-155/SOD1 pathway in sodium arsenite-induced liver injury.
Bi D, Shi M, Zheng D, Hu Q, Wang H, Peng L, Lou D, Zhang A, Hu Y
Ecotoxicology and environmental safety 2022 Sep 15;243:113990
Ecotoxicology and environmental safety 2022 Sep 15;243:113990
Avermectin induces carp neurotoxicity by mediating blood-brain barrier dysfunction, oxidative stress, inflammation, and apoptosis through PI3K/Akt and NF-κB pathways.
Zhang T, Dong Z, Liu F, Pan E, He N, Ma F, Wang G, Wang Y, Dong J
Ecotoxicology and environmental safety 2022 Sep 15;243:113961
Ecotoxicology and environmental safety 2022 Sep 15;243:113961
HDAC6 Inhibition Alleviates Anesthesia and Surgery-Induced Less Medial Prefrontal-Dorsal Hippocampus Connectivity and Cognitive Impairment in Aged Rats.
Chen J, Liu S, Wang X, Huang J, Phillips J, Ma D, Ouyang W, Tong J
Molecular neurobiology 2022 Oct;59(10):6158-6169
Molecular neurobiology 2022 Oct;59(10):6158-6169
Inka2, a novel Pak4 inhibitor, regulates actin dynamics in neuronal development.
Yamada S, Mizukoshi T, Tokunaga A, Sakakibara SI
PLoS genetics 2022 Oct;18(10):e1010438
PLoS genetics 2022 Oct;18(10):e1010438
LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway.
Cheng L, Wang H, Maboh R, Mao G, Wu X, Chen H
Journal of cardiovascular translational research 2022 Oct;15(5):971-984
Journal of cardiovascular translational research 2022 Oct;15(5):971-984
Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein.
Yang L, Chen H, Hu Q, Liu L, Yuan Y, Zhang C, Tang J, Shen X
International immunopharmacology 2022 Oct;111:109148
International immunopharmacology 2022 Oct;111:109148
p-hydroxy benzaldehyde revitalizes the microenvironment of peri-infarct cortex in rats after cerebral ischemia-reperfusion.
Yuan Y, Liu L, Du Y, Fan R, Zhang R, Zhou N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154379
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154379
Involvement of Rab11 in osteoblastic differentiation: Its up-regulation during the differentiation and by tensile stress.
Thant L, Kakihara Y, Kaku M, Kitami M, Kitami K, Mizukoshi M, Maeda T, Saito I, Saeki M
Biochemical and biophysical research communications 2022 Oct 8;624:16-22
Biochemical and biophysical research communications 2022 Oct 8;624:16-22
The Ion Channel Gene KCNAB2 Is Associated with Poor Prognosis and Loss of Immune Infiltration in Lung Adenocarcinoma.
Lyu Y, Wang Q, Liang J, Zhang L, Zhang H
Cells 2022 Oct 31;11(21)
Cells 2022 Oct 31;11(21)
Sinensetin attenuates IL-1β-induced cartilage damage and ameliorates osteoarthritis by regulating SERPINA3.
Liu Z, Liu R, Wang R, Dai J, Chen H, Wang J, Li X
Food & function 2022 Oct 3;13(19):9973-9987
Food & function 2022 Oct 3;13(19):9973-9987
RBCK1 is an endogenous inhibitor for triple negative breast cancer via hippo/YAP axis.
Li Z, Su P, Ding Y, Gao H, Yang H, Li X, Yang X, Xia Y, Zhang C, Fu M, Wang D, Zhang Y, Zhuo S, Zhu J, Zhuang T
Cell communication and signaling : CCS 2022 Oct 24;20(1):164
Cell communication and signaling : CCS 2022 Oct 24;20(1):164
Periodontal ligament fibroblasts-derived exosomes induced by PGE(2) inhibit human periodontal ligament stem cells osteogenic differentiation via activating miR-34c-5p/SATB2/ERK.
Lin C, Yang Y, Wang Y, Jing H, Bai X, Hong Z, Zhang C, Gao H, Zhang L
Experimental cell research 2022 Oct 15;419(2):113318
Experimental cell research 2022 Oct 15;419(2):113318
Angiotensin II induces podocyte metabolic reprogramming from glycolysis to glycerol-3-phosphate biosynthesis.
Luo Z, Chen Z, Zhu Z, Hao Y, Feng J, Luo Q, Zhang Z, Yang X, Hu J, Liang W, Ding G
Cellular signalling 2022 Nov;99:110443
Cellular signalling 2022 Nov;99:110443
Activation of Piezo1 contributes to matrix stiffness-induced angiogenesis in hepatocellular carcinoma.
Li M, Zhang X, Wang M, Wang Y, Qian J, Xing X, Wang Z, You Y, Guo K, Chen J, Gao D, Zhao Y, Zhang L, Chen R, Cui J, Ren Z
Cancer communications (London, England) 2022 Nov;42(11):1162-1184
Cancer communications (London, England) 2022 Nov;42(11):1162-1184
OTUB1 suppresses Hippo signaling via modulating YAP protein in gastric cancer.
Yan C, Yang H, Su P, Li X, Li Z, Wang D, Zang Y, Wang T, Liu Z, Bao Z, Dong S, Zhuang T, Zhu J, Ding Y
Oncogene 2022 Nov;41(48):5186-5198
Oncogene 2022 Nov;41(48):5186-5198
High expression of aryl hydrocarbon receptor (AhR) plays an important role in the formation of fibrous epulis.
Zeng X, Xia S, Yan X, Hu C, An K, Luo L
Oral diseases 2022 Nov;28(8):2258-2266
Oral diseases 2022 Nov;28(8):2258-2266
Therapeutic targeting of glutamate dehydrogenase 1 that links metabolic reprogramming and Snail-mediated epithelial-mesenchymal transition in drug-resistant lung cancer.
Wang Q, Wu M, Li H, Rao X, Ao L, Wang H, Yao L, Wang X, Hong X, Wang J, Aa J, Sun M, Wang G, Liu J, Zhou F
Pharmacological research 2022 Nov;185:106490
Pharmacological research 2022 Nov;185:106490
Par3 promotes breast cancer invasion and migration through pull tension and protein nanoparticle-induced osmotic pressure.
Hu Y, Xie Q, Chen S, Zhao W, Zhao X, Ruan Q, Zheng Z, Zhao H, Ma T, Guo J, Li L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113739
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113739
The m(6)A methyltransferase METTL3 promotes trophoblast cell invasion by regulating MYLK expression.
Zhao J, Ding H, Ding J, Shi X, He Y, Zhu H, Yuan H, Zhang T, Zhang J
Placenta 2022 Nov;129:1-6
Placenta 2022 Nov;129:1-6
Capsaicin suppresses hepatocarcinogenesis by inhibiting the stemness of hepatic progenitor cells via SIRT1/SOX2 signaling pathway.
Xie ZQ, Li HX, Hou XJ, Huang MY, Zhu ZM, Wei LX, Tang CX
Cancer medicine 2022 Nov;11(22):4283-4296
Cancer medicine 2022 Nov;11(22):4283-4296
Identification of MYEOV-Associated Gene Network as a Potential Therapeutic Target in Pancreatic Cancer.
Chen Y, Wang J, Guo Q, Li X, Zou X
Cancers 2022 Nov 4;14(21)
Cancers 2022 Nov 4;14(21)
A High Hepatic Uptake of Conjugated Bile Acids Promotes Colorectal Cancer-Associated Liver Metastasis.
Zheng Z, Wei J, Hou X, Jia F, Zhang Z, Guo H, Yuan F, He F, Ke Z, Wang Y, Zhao L
Cells 2022 Nov 28;11(23)
Cells 2022 Nov 28;11(23)
Bombesin receptor-activated protein exacerbates cisplatin-induced AKI by regulating the degradation of SIRT2.
Peng L, Liu D, Liu H, Xia M, Wan L, Li M, Zhao J, Tang C, Chen G, Qu X, Dong Z, Liu H
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2022 Nov 23;37(12):2366-2385
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2022 Nov 23;37(12):2366-2385
Drebrin promotes lung adenocarcinoma cell migration through inducing integrin β1 endocytosis.
Yu Q, Tang F, Cao F, Tan X, Weng L, Sun L
Biochemical and biophysical research communications 2022 Nov 19;630:175-182
Biochemical and biophysical research communications 2022 Nov 19;630:175-182
SOX4 Mediates ATRA-Induced Differentiation in Neuroblastoma Cells.
Zhang D, Gong B, Zhao Q, Li Z, Tan X, Hua Z
Cancers 2022 Nov 17;14(22)
Cancers 2022 Nov 17;14(22)
Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress.
Yang R, Yang C, Ma L, Zhao Y, Guo Z, Niu J, Chu Q, Ma Y, Li B
Nature communications 2022 Nov 17;13(1):7031
Nature communications 2022 Nov 17;13(1):7031
SYTL5 Promotes Papillary Thyroid Carcinoma Progression by Enhancing Activation of the NF-κB Signaling Pathway.
Huang D, Zeng Y, Deng HY, Fu BD, Ke Y, Luo JY, Yu JC, Yu ST
Endocrinology 2022 Nov 14;164(1)
Endocrinology 2022 Nov 14;164(1)
ATRA-mediated-crosstalk between stellate cells and Kupffer cells inhibits autophagy and promotes NLRP3 activation in acute liver injury.
Yu Z, Xie X, Su X, Lv H, Song S, Liu C, You Y, Tian M, Zhu L, Wang L, Qi J, Zhu Q
Cellular signalling 2022 May;93:110304
Cellular signalling 2022 May;93:110304
LINC01431 Promotes Histone H4R3 Methylation to Impede HBV Covalently Closed Circular DNA Transcription by Stabilizing PRMT1.
Sun Y, Teng Y, Wang L, Zhang Z, Chen C, Wang Y, Zhang X, Xiang P, Song X, Lu J, Li N, Gao L, Liang X, Xia Y, Wu Z, Ma C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 May;9(16):e2103135
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 May;9(16):e2103135
FOXO acts as a positive regulator of CncC and deltamethrin tolerance in the red flour beetle, Tribolium castaneum.
Xu X, Zhang N, Meng X, Jiang H, Ge H, Zheng Y, Qian K, Wang J
Pest management science 2022 May;78(5):1938-1945
Pest management science 2022 May;78(5):1938-1945
The hypoxia-inducible factor prolyl hydroxylase inhibitor FG4592 promotes natriuresis through upregulation of COX2 in the renal medulla.
Guan N, Zhang M, Gong WY, Mao XY, Yang SS, Hao CM
Hypertension research : official journal of the Japanese Society of Hypertension 2022 May;45(5):814-823
Hypertension research : official journal of the Japanese Society of Hypertension 2022 May;45(5):814-823
Allopregnanolone suppresses glioblastoma survival through decreasing DPYSL3 and S100A11 expression.
Feng YH, Lim SW, Lin HY, Wang SA, Hsu SP, Kao TJ, Ko CY, Hsu TI
The Journal of steroid biochemistry and molecular biology 2022 May;219:106067
The Journal of steroid biochemistry and molecular biology 2022 May;219:106067
Hydrogen-Rich Medium Regulates Cr(VI)-Induced ER Stress and Autophagy Signaling in DF-1 Cells.
Liu K, Cui Y, Li H, Qi C, Cheng G, Gao X, Zhang Z, Liu Y, Liu J
Biological trace element research 2022 May;200(5):2329-2337
Biological trace element research 2022 May;200(5):2329-2337
Inhibitory effect of aptamer-carbon dot nanomaterial-siRNA complex on the metastasis of hepatocellular carcinoma cells by interfering with FMRP.
Zhao X, Yang J, Zhang J, Wang X, Chen L, Zhang C, Shen Z
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2022 May;174:47-55
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2022 May;174:47-55
Effect of nicotinamide N-methyltransferase on lipid accumulation in 3T3-L1 adipocytes.
Xu W, Hou L, Li P, Li L
Bioengineered 2022 May;13(5):12421-12434
Bioengineered 2022 May;13(5):12421-12434
Design and synthesis of Aza-boeravinone derivatives as potential novel topoisomerase I inhibitors.
Zhou Y, Bai YP, Zhang M, Gao JM, Yang CJ, Zhang ZJ, Deng N, Li L, Liu YQ, Xu CR
Bioorganic chemistry 2022 May;122:105747
Bioorganic chemistry 2022 May;122:105747
IL-33 in the basolateral amygdala integrates neuroinflammation into anxiogenic circuits via modulating BDNF expression.
Zhuang X, Zhan B, Jia Y, Li C, Wu N, Zhao M, Chen N, Guo Y, Du Y, Zhang Y, Cao B, Li Y, Zhu F, Guo C, Wang Q, Li Y, Zhang L
Brain, behavior, and immunity 2022 May;102:98-109
Brain, behavior, and immunity 2022 May;102:98-109
STRIPAK regulation of katanin microtubule severing in the Caenorhabditis elegans embryo.
Lu T, Smit RB, Soueid H, Mains PE
Genetics 2022 May 5;221(1)
Genetics 2022 May 5;221(1)
Cholesterol determines the cytosolic entry and seeded aggregation of tau.
Tuck BJ, Miller LVC, Katsinelos T, Smith AE, Wilson EL, Keeling S, Cheng S, Vaysburd MJ, Knox C, Tredgett L, Metzakopian E, James LC, McEwan WA
Cell reports 2022 May 3;39(5):110776
Cell reports 2022 May 3;39(5):110776
A novel isoform of hydroxyacyl-CoA dehydrogenase inhibits cell proliferation.
Xia G, Gao Y, Wu C, Pan H, Hou J, Su J, Wei S, Gao X
Biochemical and biophysical research communications 2022 May 28;606:75-79
Biochemical and biophysical research communications 2022 May 28;606:75-79
Quinoline alkaloids with anti-inflammatory activity from Zanthoxylum avicennae.
Ji KL, Liu W, Yin WH, Li JY, Yue JM
Organic & biomolecular chemistry 2022 May 26;20(20):4176-4182
Organic & biomolecular chemistry 2022 May 26;20(20):4176-4182
METTL3-mediated m(6)A RNA methylation regulates dorsal lingual epithelium homeostasis.
Xiong Q, Liu C, Zheng X, Zhou X, Lei K, Zhang X, Wang Q, Lin W, Tong R, Xu R, Yuan Q
International journal of oral science 2022 May 17;14(1):26
International journal of oral science 2022 May 17;14(1):26
Nrf2 and NF-κB/NLRP3 inflammasome pathways are involved in Prototheca bovis infections of mouse mammary gland tissue and mammary epithelial cells.
Zhao W, Deng Z, Barkema HW, Xu M, Gao J, Liu G, Lin Y, Kastelic JP, Han B
Free radical biology & medicine 2022 May 1;184:148-157
Free radical biology & medicine 2022 May 1;184:148-157
Lytic cocktail: An effective method to alleviate severe burn induced hyper-metabolism through regulating white adipose tissue browning.
Zhang M, Yang P, Yu T, Harmsen MC, Gao M, Liu D, Shi Y, Liu Y, Zhang X
Heliyon 2022 Mar;8(3):e09128
Heliyon 2022 Mar;8(3):e09128
Estrogen-related Receptor α (ERRα) Functions in The Hypoxic Injury of Microglial Cells.
Deng CY, Zhu TT, Lian S, Wang JF, Wu R, Zheng JS
Journal of veterinary research 2022 Mar;66(1):131-140
Journal of veterinary research 2022 Mar;66(1):131-140
Lower expression of PDZRN3 induces endometrial carcinoma progression via the activation of canonical Wnt signaling.
Li Q, Zhong J, Yang S, Liang Y
Oncology letters 2022 Mar;23(3):98
Oncology letters 2022 Mar;23(3):98
The phytochemical, corynoline, diminishes Aurora kinase B activity to induce mitotic defect and polyploidy.
Yan Z, Shi Q, Liu X, Li J, Ahire V, Zhang S, Zhang J, Yang D, Allen TD
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Mar;147:112645
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Mar;147:112645
Inhibition of translocator protein 18 kDa suppressed the progression of glioma via the ELAV-like RNA-binding protein 1/MAPK-activated protein kinase 3 axis.
Wang J, Ren P, Zeng Z, Ma L, Li Y, Zhang H, Guo W
Bioengineered 2022 Mar;13(3):7457-7470
Bioengineered 2022 Mar;13(3):7457-7470
eEF2K promotes PD-L1 stabilization through inactivating GSK3β in melanoma.
Chen X, Wang K, Jiang S, Sun H, Che X, Zhang M, He J, Wen Y, Liao M, Li X, Zhou X, Song J, Ren X, Yi W, Yang J, Chen X, Yin M, Cheng Y
Journal for immunotherapy of cancer 2022 Mar;10(3)
Journal for immunotherapy of cancer 2022 Mar;10(3)
Moderate heart rate reduction promotes cardiac regeneration through stimulation of the metabolic pattern switch.
Tan J, Yang M, Wang H, Shen C, Wu M, Xu H, Wu Y, Li Y, Li X, Huang T, Deng S, Yang Z, Gao S, Li H, Zhou J, Chen H, Cao N, Cai W
Cell reports 2022 Mar 8;38(10):110468
Cell reports 2022 Mar 8;38(10):110468
Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer's disease.
Zeng L, Jiang H, Ashraf GM, Liu J, Wang L, Zhao K, Liu M, Li Z, Liu R
Molecular therapy. Nucleic acids 2022 Mar 8;27:256-275
Molecular therapy. Nucleic acids 2022 Mar 8;27:256-275
Loss of NPPA-AS1 promotes heart regeneration by stabilizing SFPQ-NONO heteromer-induced DNA repair.
Fu W, Ren H, Shou J, Liao Q, Li L, Shi Y, Jose PA, Zeng C, Wang WE
Basic research in cardiology 2022 Mar 5;117(1):10
Basic research in cardiology 2022 Mar 5;117(1):10
UPF1 contributes to the maintenance of endometrial cancer stem cell phenotype by stabilizing LINC00963.
Chen H, Ma J, Kong F, Song N, Wang C, Ma X
Cell death & disease 2022 Mar 22;13(3):257
Cell death & disease 2022 Mar 22;13(3):257
lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma.
Wang X, Zheng S, Yang F, Zhang W, Zhao D, Xue X, Lin Q, He Y, Hu G, Hu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Mar 2;30(3):1071-1088
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Mar 2;30(3):1071-1088
Nardilysin in adipocytes regulates UCP1 expression and body temperature homeostasis.
Saijo S, Ohno M, Iwasaki H, Matsuda S, Nishi K, Hiraoka Y, Ide N, Kimura T, Nishi E
Scientific reports 2022 Mar 2;12(1):3449
Scientific reports 2022 Mar 2;12(1):3449
IGF-1 Signaling Regulates Mitochondrial Remodeling during Myogenic Differentiation.
Guan X, Yan Q, Wang D, Du G, Zhou J
Nutrients 2022 Mar 16;14(6)
Nutrients 2022 Mar 16;14(6)
Engineering Lipusu with lysophosphatidylcholine for improved tumor cellular uptake and anticancer efficacy.
Li L, Zhan Q, Yi K, Chen N, Li X, Yang S, Hou X, Zhao J, Yuan X, Kang C
Journal of materials chemistry. B 2022 Mar 16;10(11):1833-1842
Journal of materials chemistry. B 2022 Mar 16;10(11):1833-1842
Slit guidance ligand 2 promotes the inflammatory response of periodontitis through activation of the NF-κB signaling pathway.
Sun H, Li Z, Fan C, Liu S, Yan K, Huang G, Li S
Journal of periodontal research 2022 Jun;57(3):578-586
Journal of periodontal research 2022 Jun;57(3):578-586
The TLR-chaperone CNPY3 is a critical regulator of NLRP3-inflammasome activation.
Ghait M, Husain RA, Duduskar SN, Haack TB, Rooney M, Göhrig B, Bauer M, Rubio I, Deshmukh SD
European journal of immunology 2022 Jun;52(6):907-923
European journal of immunology 2022 Jun;52(6):907-923
FLT4/VEGFR3 activates AMPK to coordinate glycometabolic reprogramming with autophagy and inflammasome activation for bacterial elimination.
Ma L, Li W, Zhang Y, Qi L, Zhao Q, Li N, Lu Y, Zhang L, Zhou F, Wu Y, He Y, Yu H, He Y, Wei B, Wang H
Autophagy 2022 Jun;18(6):1385-1400
Autophagy 2022 Jun;18(6):1385-1400
Blockade of TMEM16A protects against renal fibrosis by reducing intracellular Cl(-) concentration.
Li XL, Liu J, Chen XS, Cheng LM, Liu WL, Chen XF, Li YJ, Guan YY, Zeng X, Du YH
British journal of pharmacology 2022 Jun;179(12):3043-3060
British journal of pharmacology 2022 Jun;179(12):3043-3060
Brain aging is faithfully modelled in organotypic brain slices and accelerated by prions.
Liu Y, Senatore A, Sorce S, Nuvolone M, Guo J, Gümüş ZH, Aguzzi A
Communications biology 2022 Jun 8;5(1):557
Communications biology 2022 Jun 8;5(1):557
SUMO2-mediated SUMOylation of SH3GLB1 promotes ionizing radiation-induced hypertrophic cardiomyopathy through mitophagy activation.
Gao A, Zou J, Mao Z, Zhou H, Zeng G
European journal of pharmacology 2022 Jun 5;924:174980
European journal of pharmacology 2022 Jun 5;924:174980
Long noncoding RNA GAS5 attenuates cigarette smoke-induced airway remodeling by regulating miR-217-5p/PTEN axis.
Du Y, Ding Y, Shi T, He W, Feng J, Mei Z, Chen X, Feng X, Zhang X, Jie Z
Acta biochimica et biophysica Sinica 2022 Jun 25;54(7):931-939
Acta biochimica et biophysica Sinica 2022 Jun 25;54(7):931-939
The Expression and Role Analysis of Methylation-Regulated Differentially Expressed Gene UBE2C in Pan-Cancer, Especially for HGSOC.
Li J, Sun Y, Zhi X, Li Q, Yao L, Chen M
Cancers 2022 Jun 25;14(13)
Cancers 2022 Jun 25;14(13)
ARIH2 regulates the proliferation, DNA damage and chemosensitivity of gastric cancer cells by reducing the stability of p21 via ubiquitination.
Geng S, Peng W, Wang X, Hu X, Liang H, Hou J, Wang F, Zhao G, Lü M, Cui H
Cell death & disease 2022 Jun 22;13(6):564
Cell death & disease 2022 Jun 22;13(6):564
Mitochondrial FAD shortage in SLC25A32 deficiency affects folate-mediated one-carbon metabolism.
Peng MZ, Shao YX, Li XZ, Zhang KD, Cai YN, Lin YT, Jiang MY, Liu ZC, Su XY, Zhang W, Jiang XL, Liu L
Cellular and molecular life sciences : CMLS 2022 Jun 21;79(7):375
Cellular and molecular life sciences : CMLS 2022 Jun 21;79(7):375
In vitro and in vivo assay of the ER lipid scramblase TMEM41B.
Wu L, Liu L, Xu B, Huang D, Chen XW
STAR protocols 2022 Jun 17;3(2):101333
STAR protocols 2022 Jun 17;3(2):101333
Silencing GOLGA8B inhibits cell invasion and metastasis by suppressing STAT3 signaling pathway in lung squamous cell carcinoma.
Li Z, Li Y, Li N, Shen L, Liu A
Clinical science (London, England : 1979) 2022 Jun 17;136(11):895-909
Clinical science (London, England : 1979) 2022 Jun 17;136(11):895-909
Perfluorooctane sulfonate induces mitochondrial calcium overload and early hepatic insulin resistance via autophagy/detyrosinated alpha-tubulin-regulated IP3R2-VDAC1-MICU1 interaction.
Dong Z, Wang J, Qiu T, Wu J, An Y, Shi X, Sun X, Jiang L, Liu X, Yang G, Cao J, Yao X
The Science of the total environment 2022 Jun 15;825:153933
The Science of the total environment 2022 Jun 15;825:153933
The hsa-miR-214-3p/ATGL axis regulates aberrant lipolysis to promote acute myeloid leukemia progression via PPARα in vitro.
Li Y, Yuan S, Wu W, Zhou J, Zhang P, Li D, Zhang Y, Lou S
Biochemical and biophysical research communications 2022 Jun 11;608:73-81
Biochemical and biophysical research communications 2022 Jun 11;608:73-81
Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death.
Sun Y, Yang YM, Hu YY, Ouyang L, Sun ZH, Yin XF, Li N, He QY, Wang Y
Redox biology 2022 Jul;53:102334
Redox biology 2022 Jul;53:102334
Downregulation of HINFP induces senescence-associated secretory phenotype to promote metastasis in a non-cell-autonomous manner in bladder cancer.
Zheng X, Liu Z, Zhong J, Zhou L, Chen J, Zheng L, Li Z, Zhang R, Pan J, Wu Y, Liu Z, Kang T
Oncogene 2022 Jul;41(28):3587-3598
Oncogene 2022 Jul;41(28):3587-3598
TET2-BCLAF1 transcription repression complex epigenetically regulates the expression of colorectal cancer gene Ascl2 via methylation of its promoter.
Shang Y, Jiang T, Ran L, Hu W, Wu Y, Ye J, Peng Z, Chen L, Wang R
The Journal of biological chemistry 2022 Jul;298(7):102095
The Journal of biological chemistry 2022 Jul;298(7):102095
Iron-regulated assembly of the cytosolic iron-sulfur cluster biogenesis machinery.
Fan X, Barshop WD, Vashisht AA, Pandey V, Leal S, Rayatpisheh S, Jami-Alahmadi Y, Sha J, Wohlschlegel JA
The Journal of biological chemistry 2022 Jul;298(7):102094
The Journal of biological chemistry 2022 Jul;298(7):102094
Ciliary transition zone proteins coordinate ciliary protein composition and ectosome shedding.
Wang L, Wen X, Wang Z, Lin Z, Li C, Zhou H, Yu H, Li Y, Cheng Y, Chen Y, Lou G, Pan J, Cao M
Nature communications 2022 Jul 9;13(1):3997
Nature communications 2022 Jul 9;13(1):3997
TRIM25 inhibits influenza A virus infection, destabilizes viral mRNA, but is redundant for activating the RIG-I pathway.
Choudhury NR, Trus I, Heikel G, Wolczyk M, Szymanski J, Bolembach A, Dos Santos Pinto RM, Smith N, Trubitsyna M, Gaunt E, Digard P, Michlewski G
Nucleic acids research 2022 Jul 8;50(12):7097-7114
Nucleic acids research 2022 Jul 8;50(12):7097-7114
Box C/D snoRNA SNORD89 influences the occurrence and development of endometrial cancer through 2'-O-methylation modification of Bim.
Bao HJ, Chen X, Liu X, Wu W, Li QH, Xian JY, Zhao Y, Chen S
Cell death discovery 2022 Jul 5;8(1):309
Cell death discovery 2022 Jul 5;8(1):309
Peptide PDHPS1 Inhibits Ovarian Cancer Growth through Disrupting YAP Signaling.
Pan X, Geng Z, Li J, Li X, Zhang M, Wang X, Cong Y, Huang K, Xu J, Jia X
Molecular cancer therapeutics 2022 Jul 5;21(7):1160-1170
Molecular cancer therapeutics 2022 Jul 5;21(7):1160-1170
Impaired Bestrophin Channel Activity in an iPSC-RPE Model of Best Vitelliform Macular Dystrophy (BVMD) from an Early Onset Patient Carrying the P77S Dominant Mutation.
Navinés-Ferrer A, Ruiz-Nogales S, Navarro R, Pomares E
International journal of molecular sciences 2022 Jul 4;23(13)
International journal of molecular sciences 2022 Jul 4;23(13)
White tea alleviates non-alcoholic fatty liver disease by regulating energy expenditure and lipid metabolism.
Li N, Zhou X, Wang J, Chen J, Lu Y, Sun Y, Song Y, Tan X, Xie G, Chen Y, Zhang L
Gene 2022 Jul 30;833:146553
Gene 2022 Jul 30;833:146553
Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy.
Li L, Feng Y, Zhang J, Zhang Q, Ren J, Sun C, Li S, Lei X, Luo G, Hu J, Huang Y
Cell communication and signaling : CCS 2022 Jul 28;20(1):115
Cell communication and signaling : CCS 2022 Jul 28;20(1):115
Effects of Artemisinin on Escherichia coli-Induced Mastitis in Bovine Mammary Epithelial Cells and Mice.
Li Z, Hu J, Wang X, Du Y, Yin J, Gao J, Han B, Cui S, Liu Y, Liu J
Veterinary sciences 2022 Jul 26;9(8)
Veterinary sciences 2022 Jul 26;9(8)
Mitochondria-Targeting Polymer Micelle of Dichloroacetate Induced Pyroptosis to Enhance Osteosarcoma Immunotherapy.
Jin J, Yuan P, Yu W, Lin J, Xu A, Xu X, Lou J, Yu T, Qian C, Liu B, Song J, Li L, Piao Y, Xie T, Shen Y, Tao H, Tang J
ACS nano 2022 Jul 26;16(7):10327-10340
ACS nano 2022 Jul 26;16(7):10327-10340
C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.
Ru Y, Yan X, Zhang B, Song L, Feng Q, Ye C, Zhou Z, Yang Z, Li Y, Zhang Z, Li Q, Mi W, Dong C
Proceedings of the National Academy of Sciences of the United States of America 2022 Jul 26;119(30):e2203218119
Proceedings of the National Academy of Sciences of the United States of America 2022 Jul 26;119(30):e2203218119
Effect of Houpo-Mahuang Decoction on aggravated asthma induced by cigarette smoke and the expression of TRPA1 and tight junctions in mice.
Sun YB, Ni Y, Fan XS, Zhou LP, Yue QF, Shang EX
Journal of ethnopharmacology 2022 Jul 15;293:115217
Journal of ethnopharmacology 2022 Jul 15;293:115217
Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.
Lyu Z, Sycks MM, Espinoza MF, Nguyen KK, Montoya MR, Galapate CM, Mei L, Genereux JC
ACS chemical biology 2022 Jul 15;17(7):1963-1977
ACS chemical biology 2022 Jul 15;17(7):1963-1977
ZEB2/TWIST1/PRMT5/NuRD Multicomplex Contributes to the Epigenetic Regulation of EMT and Metastasis in Colorectal Carcinoma.
Zheng Y, Dai M, Dong Y, Yu H, Liu T, Feng X, Yu B, Zhang H, Wu J, Kong W, Yu X, Wu H
Cancers 2022 Jul 14;14(14)
Cancers 2022 Jul 14;14(14)
Fine-Tuning of Cholesterol Homeostasis Controls Erythroid Differentiation.
Lu Z, Huang L, Li Y, Xu Y, Zhang R, Zhou Q, Sun Q, Lu Y, Chen J, Shen Y, Li J, Zhao B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(2):e2102669
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(2):e2102669
Caveolin-1 negatively regulates inflammation and fibrosis in silicosis.
He R, Yuan X, Lv X, Liu Q, Tao L, Meng J
Journal of cellular and molecular medicine 2022 Jan;26(1):99-107
Journal of cellular and molecular medicine 2022 Jan;26(1):99-107
Butyrate ameliorates skeletal muscle atrophy in diabetic nephropathy by enhancing gut barrier function and FFA2-mediated PI3K/Akt/mTOR signals.
Tang G, Du Y, Guan H, Jia J, Zhu N, Shi Y, Rong S, Yuan W
British journal of pharmacology 2022 Jan;179(1):159-178
British journal of pharmacology 2022 Jan;179(1):159-178
Virus-induced FoxO factor facilitates replication of human cytomegalovirus.
Sleman S
Archives of virology 2022 Jan;167(1):109-121
Archives of virology 2022 Jan;167(1):109-121
MACF1 promotes osteoblastic cell migration by regulating MAP1B through the GSK3beta/TCF7 pathway.
Su P, Tian Y, Yin C, Wang X, Li D, Yang C, Pei J, Deng X, King S, Li Y, Qian A
Bone 2022 Jan;154:116238
Bone 2022 Jan;154:116238
Dihydroartemisinin enhances the inhibitory effect of sorafenib on HepG2 cells by inducing ferroptosis and inhibiting energy metabolism.
Cui Z, Wang H, Li S, Qin T, Shi H, Ma J, Li L, Yu G, Jiang T, Li C
Journal of pharmacological sciences 2022 Jan;148(1):73-85
Journal of pharmacological sciences 2022 Jan;148(1):73-85
Overexpression of sFlt-1 represses ox-LDL-induced injury of HUVECs by activating autophagy via PI3K/AKT/mTOR pathway.
Zhou YH, Tang YZ, Guo LY, Zheng LL, Zhang D, Yang CY, Wang W
Microvascular research 2022 Jan;139:104252
Microvascular research 2022 Jan;139:104252
High expression of small nucleolar RNA host gene 3 predicts poor prognosis and promotes bone metastasis in prostate cancer by activating transforming growth factor-beta signaling.
Xi X, Hu Z, Wu Q, Hu K, Cao Z, Zhou J, Liao J, Zhang Z, Hu Y, Zhong X, Bao Y
Bioengineered 2022 Jan;13(1):1895-1907
Bioengineered 2022 Jan;13(1):1895-1907
αTAT1-induced tubulin acetylation promotes ameloblastoma migration and invasion.
Yoshimoto S, Morita H, Okamura K, Hiraki A, Hashimoto S
Laboratory investigation; a journal of technical methods and pathology 2022 Jan;102(1):80-89
Laboratory investigation; a journal of technical methods and pathology 2022 Jan;102(1):80-89
Curcumin reduces oxidative stress and fat deposition in longissimus dorsi muscle of intrauterine growth-retarded finishing pigs.
Zhang J, Yan E, Zhang L, Wang T, Wang C
Animal science journal = Nihon chikusan Gakkaiho 2022 Jan-Dec;93(1):e13741
Animal science journal = Nihon chikusan Gakkaiho 2022 Jan-Dec;93(1):e13741
Bifidobacterium spp. and their metabolite lactate protect against acute pancreatitis via inhibition of pancreatic and systemic inflammatory responses.
Li H, Xie J, Guo X, Yang G, Cai B, Liu J, Yue M, Tang Y, Wang G, Chen S, Guo J, Qi X, Wang D, Zheng H, Liu W, Yu H, Wang C, Zhu SJ, Guo F
Gut microbes 2022 Jan-Dec;14(1):2127456
Gut microbes 2022 Jan-Dec;14(1):2127456
Oncogenic role of the SOX9-DHCR24-cholesterol biosynthesis axis in IGH-BCL2+ diffuse large B-cell lymphomas.
Shen Y, Zhou J, Nie K, Cheng S, Chen Z, Wang W, Wei W, Jiang D, Peng Z, Ren Y, Zhang Y, Fan Q, Richards KL, Qi Y, Cheng J, Tam W, Ma J
Blood 2022 Jan 6;139(1):73-86
Blood 2022 Jan 6;139(1):73-86
SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease.
Li W, Feng W, Su X, Luo D, Li Z, Zhou Y, Zhu Y, Zhang M, Chen J, Liu B, Huang H
The Journal of clinical investigation 2022 Jan 4;132(1)
The Journal of clinical investigation 2022 Jan 4;132(1)
m6A modifications regulate intestinal immunity and rotavirus infection.
Wang A, Tao W, Tong J, Gao J, Wang J, Hou G, Qian C, Zhang G, Li R, Wang D, Ren X, Zhang K, Ding S, Flavell RA, Li H, Pan W, Zhu S
eLife 2022 Jan 31;11
eLife 2022 Jan 31;11
The ethanol extract of flower buds of Tussilago farfara L. attenuates cigarette smoke-induced lung inflammation through regulating NLRP3 inflammasome, Nrf2, and NF-κB.
Xu LT, Wang T, Fang KL, Zhao Y, Wang XN, Ren DM, Shen T
Journal of ethnopharmacology 2022 Jan 30;283:114694
Journal of ethnopharmacology 2022 Jan 30;283:114694
The Role of Sirtuin 1 in Palmitic Acid-Induced Endoplasmic Reticulum Stress in Cardiac Myoblasts.
Yang HY, Chen JY, Huo YN, Yu PL, Lin PZ, Hsu SC, Huang SM, Tsai CS, Lin CY
Life (Basel, Switzerland) 2022 Jan 26;12(2)
Life (Basel, Switzerland) 2022 Jan 26;12(2)
Regulation of TET2 gene expression and 5mC oxidation in breast cancer cells by estrogen signaling.
Zhu X, Xiong L, Lyu R, Shen Y, Liu L, Li S, Argueta C, Tan L
Biochemical and biophysical research communications 2022 Jan 22;589:240-246
Biochemical and biophysical research communications 2022 Jan 22;589:240-246
ZC3H15 promotes gastric cancer progression by targeting the FBXW7/c-Myc pathway.
Hou J, Huang P, Lan C, Geng S, Xu M, Liu Y, Chang H, Wang Z, Gu H, Wang Y, Yang G, Cui H
Cell death discovery 2022 Jan 21;8(1):32
Cell death discovery 2022 Jan 21;8(1):32
PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40.
Zhang T, Wang Y, Yu H, Zhang T, Guo L, Xu J, Wei X, Wang N, Wu Y, Wang X, Huang L
Cell death & disease 2022 Jan 20;13(1):68
Cell death & disease 2022 Jan 20;13(1):68
The Ancient and Evolved Mouse Sperm-Associated Antigen 6 Genes Have Different Biologic Functions In Vivo.
Yap YT, Li W, Zhou Q, Haj-Diab S, Chowdhury DD, Vaishnav A, Harding P, Williams DC Jr, Edwards BF, Strauss JF 3rd, Zhang Z
Cells 2022 Jan 20;11(3)
Cells 2022 Jan 20;11(3)
KCTD10 regulates brown adipose tissue thermogenesis and metabolic function via Notch signaling.
Ye MS, Luo L, Guo Q, Su T, Cheng P, Huang Y
The Journal of endocrinology 2022 Jan 13;252(3):155-166
The Journal of endocrinology 2022 Jan 13;252(3):155-166
ZC3H15 promotes glioblastoma progression through regulating EGFR stability.
Hou J, Xu M, Gu H, Pei D, Liu Y, Huang P, Chang H, Cui H
Cell death & disease 2022 Jan 13;13(1):55
Cell death & disease 2022 Jan 13;13(1):55
Aging is associated with increased brain iron through cortex-derived hepcidin expression.
Sato T, Shapiro JS, Chang HC, Miller RA, Ardehali H
eLife 2022 Jan 11;11
eLife 2022 Jan 11;11
Bombyx mori Akirin hijacks a viral peptide vSP27 encoded by BmCPV circRNA and activates the ROS-NF-κB pathway against viral infection.
Zhang Y, Zhang X, Dai K, Zhu M, Liang Z, Pan J, Zhang Z, Xue R, Cao G, Hu X, Gong C
International journal of biological macromolecules 2022 Jan 1;194:223-232
International journal of biological macromolecules 2022 Jan 1;194:223-232
Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress via modulation of Keap1/Nrf2 signaling pathway.
Qi Y, Fu S, Pei D, Fang Q, Xin W, Yuan X, Cao Y, Shu Q, Mi X, Luo F
Free radical research 2022 Feb;56(2):209-221
Free radical research 2022 Feb;56(2):209-221
Alkbh1-mediated DNA N6-methyladenine modification regulates bone marrow mesenchymal stem cell fate during skeletal aging.
Cai GP, Liu YL, Luo LP, Xiao Y, Jiang TJ, Yuan J, Wang M
Cell proliferation 2022 Feb;55(2):e13178
Cell proliferation 2022 Feb;55(2):e13178
LncRNA Riken Attenuated Sevoflurane-Induced Neuroinflammation by Regulating the MicroRNA-101a/MKP-1/JNK Pathway.
Hou Q, Li S, Zhang B, Chu H, Ni C, Fei X, Zheng H
Neurotoxicity research 2022 Feb;40(1):186-197
Neurotoxicity research 2022 Feb;40(1):186-197
RNF6 promotes the migration and invasion of breast cancer by promoting the ubiquitination and degradation of MST1.
Huang Y, Zou Y, Jie Z
Experimental and therapeutic medicine 2022 Feb;23(2):118
Experimental and therapeutic medicine 2022 Feb;23(2):118
Polarity protein Par3 sensitizes breast cancer to paclitaxel by promoting cell cycle arrest.
Zhao Y, Peng H, Liang L, Li Y, Hu X, Wang B, Xu Y, Chen S
Breast cancer research and treatment 2022 Feb;192(1):75-87
Breast cancer research and treatment 2022 Feb;192(1):75-87
The phosphatase of regenerating liver-3 protein (PRL-3) promotes glioma cell invasiveness by interacting with β3 -tubulin.
Ge Z, Gu T, Zhang L, Fan Q, Ma L, Fang N
Bioengineered 2022 Feb;13(2):4112-4121
Bioengineered 2022 Feb;13(2):4112-4121
Effect of resistance training on satellite cells in old mice - a transcriptome study : implications for sarcopenia.
Hsu WB, Lin SJ, Hung JS, Chen MH, Lin CY, Hsu WH, Hsu WR
Bone & joint research 2022 Feb;11(2):121-133
Bone & joint research 2022 Feb;11(2):121-133
Metabolic Reprogramming in Response to Alterations of Mitochondrial DNA and Mitochondrial Dysfunction in Gastric Adenocarcinoma.
Chang TC, Lee HT, Pan SC, Cho SH, Cheng C, Ou LH, Lin CI, Lin CS, Wei YH
International journal of molecular sciences 2022 Feb 6;23(3)
International journal of molecular sciences 2022 Feb 6;23(3)
HDAC9 Contributes to Serous Ovarian Cancer Progression through Regulating Epithelial-Mesenchymal Transition.
Xu L, Wang J, Liu B, Fu J, Zhao Y, Yu S, Shen L, Yan X, Su J
Biomedicines 2022 Feb 3;10(2)
Biomedicines 2022 Feb 3;10(2)
Targeting polarized phenotype of microglia via IL6/JAK2/STAT3 signaling to reduce NSCLC brain metastasis.
Jin Y, Kang Y, Wang M, Wu B, Su B, Yin H, Tang Y, Li Q, Wei W, Mei Q, Hu G, Lukacs-Kornek V, Li J, Wu K, Yuan X, Wang W
Signal transduction and targeted therapy 2022 Feb 23;7(1):52
Signal transduction and targeted therapy 2022 Feb 23;7(1):52
Cucurbitacin E inhibits cellular proliferation and induces apoptosis in melanoma by suppressing HSDL2 expression.
Liu WB, Wang HL, Chen L, Tang B, Ke G, Wang S, Sun YQ, Ma J, Lyu DL
Chinese medicine 2022 Feb 22;17(1):28
Chinese medicine 2022 Feb 22;17(1):28
Impaired KDM2B-mediated PRC1 recruitment to chromatin causes defective neural stem cell self-renewal and ASD/ID-like behaviors.
Gao Y, Duque-Wilckens N, Aljazi MB, Moeser AJ, Mias GI, Robison AJ, Zhang Y, He J
iScience 2022 Feb 18;25(2):103742
iScience 2022 Feb 18;25(2):103742
PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease.
Li J, Lai M, Zhang X, Li Z, Yang D, Zhao M, Wang D, Sun Z, Ehsan S, Li W, Gao H, Zhao D, Yang L
Cell death & disease 2022 Feb 18;13(2):162
Cell death & disease 2022 Feb 18;13(2):162
Hypoxic training upregulates mitochondrial turnover and angiogenesis of skeletal muscle in mice.
Zhao YC, Guo W, Gao BH
Life sciences 2022 Feb 15;291:119340
Life sciences 2022 Feb 15;291:119340
MRCK-Alpha and Its Effector Myosin II Regulatory Light Chain Bind ABCB4 and Regulate Its Membrane Expression.
Bruneau A, Delaunay JL, Durand-Schneider AM, Vauthier V, Ben Saad A, Aoudjehane L, El Mourabit H, Morichon R, Falguières T, Gautheron J, Housset C, Aït-Slimane T
Cells 2022 Feb 10;11(4)
Cells 2022 Feb 10;11(4)
N(6) -Methyladenosine-Modified CBX1 Regulates Nasopharyngeal Carcinoma Progression Through Heterochromatin Formation and STAT1 Activation.
Zhao Y, Huang S, Tan X, Long L, He Q, Liang X, Bai J, Li Q, Lin J, Li Y, Liu N, Ma J, Chen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Dec;9(36):e2205091
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Dec;9(36):e2205091
TERC suppresses PD-L1 expression by downregulating RNA binding protein HuR.
Jin H, Chen Y, Ren J, Huang J, Zhao Y, Liu H
Science China. Life sciences 2022 Dec;65(12):2505-2516
Science China. Life sciences 2022 Dec;65(12):2505-2516
Qiangli Wuhu mixture alleviates LPS-induced pneumonia by inhibiting the TLR4/NF-κB/NLRP3 pathway: a study based on network pharmacology.
Tian J, Wang XL, Wang LC, Chen F, Tian Y, Ma L, Pan CY, Wang YP
Pharmaceutical biology 2022 Dec;60(1):1331-1340
Pharmaceutical biology 2022 Dec;60(1):1331-1340
Myostain is involved in ginsenoside Rb1-mediated anti-obesity.
Li HS, Kuang JY, Liu GJ, Wu WJ, Yin XL, Li HD, Wang L, Qin T, Zhang WC, Sun YY
Pharmaceutical biology 2022 Dec;60(1):1106-1115
Pharmaceutical biology 2022 Dec;60(1):1106-1115
Low STING expression promotes endometrial stromal cell invasion and migration via the STING/IRF-3/IFN-β1 pathway in eutopic endometrium of women with endometriosis.
Xu Z, Zhao H, Yue C, Zhang L, Li M, Du Y, Zhang N, Yan L
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2022 Dec;38(12):1129-1135
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2022 Dec;38(12):1129-1135
Human cytomegalovirus UL24 and UL43 products participate in SAMHD1 subcellular localization.
Sleman S, Najmuldeen H, Hao H, Jalal P, Saeed N, Othman D, Qian Z
Virusdisease 2022 Dec;33(4):383-396
Virusdisease 2022 Dec;33(4):383-396
The interaction between E3 ubiquitin ligase Parkin and mitophagy receptor PHB2 links inner mitochondrial membrane ubiquitination to efficient mitophagy.
Sun S, Hou H, Ma G, Ma Q, Li N, Zhang L, Dong C, Cao M, Tam KY, Ying Z, Wang H
The Journal of biological chemistry 2022 Dec;298(12):102704
The Journal of biological chemistry 2022 Dec;298(12):102704
CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer's disease.
Xie W, Guo D, Li J, Yue L, Kang Q, Chen G, Zhou T, Wang H, Zhuang K, Leng L, Li H, Chen Z, Gao W, Zhang J
Cell death and differentiation 2022 Dec;29(12):2417-2428
Cell death and differentiation 2022 Dec;29(12):2417-2428
IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas.
Tong S, Ye L, Xu Y, Sun Q, Gao L, Cai J, Ye Z, Tian D, Chen Q
Translational oncology 2022 Dec;26:101544
Translational oncology 2022 Dec;26:101544
In Vitro Inhibitory Effects of Maqian Essential Oil against Ectopic Endometrial Stromal Cells and LPS-Induced Endometrial Epithelial Cells.
Li LP, Luo Y, Huang C, Wang XR, Huang TT, Zou YY, Huang SH, Liu YQ, Yang BC
Chemistry & biodiversity 2022 Dec;19(12):e202200756
Chemistry & biodiversity 2022 Dec;19(12):e202200756
Tumor-targeted dual-starvation therapy based on redox-responsive micelle nanosystem with co-loaded LND and BPTES.
Fu Z, Du H, Meng S, Yao M, Zhao P, Li X, Zheng X, Yuan Z, Yang H, Cai K, Dai L
Materials today. Bio 2022 Dec;16:100449
Materials today. Bio 2022 Dec;16:100449
The transcription factor KLF14 attenuates LPS-induced acute lung injury by ameliorating apoptosis of alveolar epithelial cells in mice.
Liu L, Yuan Y, Zhou Y, Yao L, Li J, Chen F
Molecular immunology 2022 Dec;152:67-77
Molecular immunology 2022 Dec;152:67-77
Gut dysbacteriosis attenuates resistance to Mycobacterium bovis infection by decreasing cyclooxygenase 2 to inhibit endoplasmic reticulum stress.
Wang H, Yao J, Chen Y, Wang Y, Liu Y, Liao Y, Liang Z, Dong YH, Qu M, Ge X, Zhou X
Emerging microbes & infections 2022 Dec;11(1):1806-1818
Emerging microbes & infections 2022 Dec;11(1):1806-1818
Circ-CREBBP inhibits sperm apoptosis via the PI3K-Akt signaling pathway by sponging miR-10384 and miR-143-3p.
Ding N, Zhang Y, Huang M, Liu J, Wang C, Zhang C, Cao J, Zhang Q, Jiang L
Communications biology 2022 Dec 7;5(1):1339
Communications biology 2022 Dec 7;5(1):1339
HDAC6 Inhibition Alleviates Ischemia- and Cisplatin-Induced Acute Kidney Injury by Promoting Autophagy.
Shi L, Song Z, Li C, Deng F, Xia Y, Huang J, Wu X, Zhu J
Cells 2022 Dec 7;11(24)
Cells 2022 Dec 7;11(24)
The central scaffold protein CEP350 coordinates centriole length, stability, and maturation.
Karasu OR, Neuner A, Atorino ES, Pereira G, Schiebel E
The Journal of cell biology 2022 Dec 5;221(12)
The Journal of cell biology 2022 Dec 5;221(12)
Wnt/β-Catenin Signaling Inhibits Osteogenic Differentiation in Human Periodontal Ligament Fibroblasts.
Iizumi R, Honda M
Biomimetics (Basel, Switzerland) 2022 Dec 3;7(4)
Biomimetics (Basel, Switzerland) 2022 Dec 3;7(4)
RNF31 represses cell progression and immune evasion via YAP/PD-L1 suppression in triple negative breast Cancer.
Yang H, Xue M, Su P, Zhou Y, Li X, Li Z, Xia Y, Zhang C, Fu M, Zheng X, Luo G, Wei T, Wang X, Ding Y, Zhu J, Zhuang T
Journal of experimental & clinical cancer research : CR 2022 Dec 29;41(1):364
Journal of experimental & clinical cancer research : CR 2022 Dec 29;41(1):364
C/D box small nucleolar RNA SNORD104 promotes endometrial cancer by regulating the 2'-O-methylation of PARP1.
Lu B, Chen X, Liu X, Chen J, Qin H, Chen S, Zhao Y
Journal of translational medicine 2022 Dec 24;20(1):618
Journal of translational medicine 2022 Dec 24;20(1):618
WNT6 participates in the occurrence and development of ovarian cancer by upregulating/activating the typical Wnt pathway and Notch1 signaling pathway.
Bao H, Wu W, Li Y, Zong Z, Chen S
Gene 2022 Dec 20;846:146871
Gene 2022 Dec 20;846:146871
De novo non-synonymous DPYSL2 (CRMP2) variants in two patients with intellectual disabilities and documentation of functional relevance through zebrafish rescue and cellular transfection experiments.
Suzuki H, Li S, Tokutomi T, Takeuchi C, Takahashi M, Yamada M, Okuno H, Miya F, Takenouchi T, Numabe H, Kosaki K, Ohshima T
Human molecular genetics 2022 Dec 16;31(24):4173-4182
Human molecular genetics 2022 Dec 16;31(24):4173-4182
The Photoperiod Regulates Granulosa Cell Apoptosis through the FSH-Nodal/ALK7 Signaling Pathway in Phodopus sungorus.
Qi Y, Xue HL, Zheng YJ, Yin YF, Xu WL, Xu JH, Wu M, Chen L, Xu LX
Animals : an open access journal from MDPI 2022 Dec 16;12(24)
Animals : an open access journal from MDPI 2022 Dec 16;12(24)
Oxidative stress modulates expression of immune checkpoint genes via activation of AhR signaling.
Kou Z, Yang R, Lee E, Cuddapah S, Choi BH, Dai W
Toxicology and applied pharmacology 2022 Dec 15;457:116314
Toxicology and applied pharmacology 2022 Dec 15;457:116314
Anti-tumor effects and mechanism of a novel camptothecin derivative YCJ100.
Zhang M, Fu W, Zhu LZ, Liu XF, Li L, Peng LZ, Kai GY, Liu YQ, Zhang ZJ, Xu CR
Life sciences 2022 Dec 15;311(Pt A):121105
Life sciences 2022 Dec 15;311(Pt A):121105
miR21 modulates the Hippo signaling pathway via interference with PP2A Bβ to inhibit trophoblast invasion and cause preeclampsia.
Hu M, Zheng Y, Liao J, Wen L, Cheng J, Huang J, Huang B, Lin L, Long Y, Wu Y, Ye X, Fu Y, Qi H, Baker PN, Tong C
Molecular therapy. Nucleic acids 2022 Dec 13;30:143-161
Molecular therapy. Nucleic acids 2022 Dec 13;30:143-161
TOPK Activation Exerts Protective Effects on Cisplatin-induced Acute Kidney Injury.
Zhang H, Dong QQ, Shu HP, Tu YC, Liao QQ, Yao LJ
Current medical science 2022 Aug;42(4):742-753
Current medical science 2022 Aug;42(4):742-753
N(6)-methyladenosine (m(6)A) in 18S rRNA promotes fatty acid metabolism and oncogenic transformation.
Peng H, Chen B, Wei W, Guo S, Han H, Yang C, Ma J, Wang L, Peng S, Kuang M, Lin S
Nature metabolism 2022 Aug;4(8):1041-1054
Nature metabolism 2022 Aug;4(8):1041-1054
Knockdown of bone morphogenetic protein 4 gene induces apoptosis and inhibits proliferation of bovine cumulus cells.
Tian YQ, Li XL, Wang WJ, Hao HS, Zou HY, Pang YW, Zhao XM, Zhu HB, Du WH
Theriogenology 2022 Aug;188:28-36
Theriogenology 2022 Aug;188:28-36
GPR108 is required for gambogic acid inhibiting NF-κB signaling in cancer.
Lyu S, Zhang X, Tu Z, Zhou H, Ke X, Qu Y
Pharmacological research 2022 Aug;182:106279
Pharmacological research 2022 Aug;182:106279
PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression.
Lan X, Ding S, Zhang T, Yi Y, Li C, Jin W, Chen J, Liang K, Wang H, Jiang W
Nature communications 2022 Aug 6;13(1):4601
Nature communications 2022 Aug 6;13(1):4601
Targeting HECTD3-IKKα axis inhibits inflammation-related metastasis.
Li F, Liang H, You H, Xiao J, Xia H, Chen X, Huang M, Cheng Z, Yang C, Liu W, Zhang H, Zeng L, Wu Y, Ge F, Li Z, Zhou W, Wen Y, Zhou Z, Liu R, Jiang D, Xie N, Liang B, Liu Z, Kong Y, Chen C
Signal transduction and targeted therapy 2022 Aug 3;7(1):264
Signal transduction and targeted therapy 2022 Aug 3;7(1):264
mTORC1 Mediates the Processes of Lysine Regulating Satellite Cells Proliferation, Apoptosis, and Autophagy.
Liu M, Yue Z, Zhang B, Li F, Liu L, Li F
Metabolites 2022 Aug 25;12(9)
Metabolites 2022 Aug 25;12(9)
Forsythiaside A Improves the Inhibitory Efficiency of Recombinant Protein Vaccines against Bovine Viral Diarrhea Virus Infection.
Yang G, Wang J, Wang S, Zhu Y
International journal of molecular sciences 2022 Aug 20;23(16)
International journal of molecular sciences 2022 Aug 20;23(16)
A mechanosensitive lipolytic factor in the bone marrow promotes osteogenesis and lymphopoiesis.
Peng H, Hu B, Xie LQ, Su T, Li CJ, Liu Y, Yang M, Xiao Y, Feng X, Zhou R, Guo Q, Zhou HY, Huang Y, Jiang TJ, Luo XH
Cell metabolism 2022 Aug 2;34(8):1168-1182.e6
Cell metabolism 2022 Aug 2;34(8):1168-1182.e6
Anionic nanoplastic exposure induces endothelial leakiness.
Wei W, Li Y, Lee M, Andrikopoulos N, Lin S, Chen C, Leong DT, Ding F, Song Y, Ke PC
Nature communications 2022 Aug 13;13(1):4757
Nature communications 2022 Aug 13;13(1):4757
cAMP-Induced Nuclear Condensation of CRTC2 Promotes Transcription Elongation and Cystogenesis in Autosomal Dominant Polycystic Kidney Disease.
Mi Z, Song Y, Wang J, Liu Z, Cao X, Dang L, Lu Y, Sun Y, Xiong H, Zhang L, Chen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Apr;9(10):e2104578
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Apr;9(10):e2104578
Successful outcomes of intracytoplasmic sperm injection-embryo transfer using ejaculated spermatozoa from two Chinese asthenoteratozoospermic brothers with a compound heterozygous FSIP2 mutation.
Yuan Y, Xu WQ, Chen ZY, Chen Y, Zhang L, Zheng L, Luo T, Chen HY
Andrologia 2022 Apr;54(3):e14351
Andrologia 2022 Apr;54(3):e14351
Aurora kinase blockade drives de novo addiction of cervical squamous cell carcinoma to druggable EGFR signalling.
Komatsu M, Nakamura K, Takeda T, Chiwaki F, Banno K, Aoki D, Takeshita F, Sasaki H
Oncogene 2022 Apr;41(16):2326-2339
Oncogene 2022 Apr;41(16):2326-2339
Time-dependent expression of ryanodine receptors in sea urchin eggs, zygotes and early embryos.
Percivale G, Angelini C, Falugi C, Picco C, Prestipino G
Zygote (Cambridge, England) 2022 Apr;30(2):213-216
Zygote (Cambridge, England) 2022 Apr;30(2):213-216
Silencing integrin α6 enhances the pluripotency-differentiation transition in human dental pulp stem cells.
Zhang W, Shen J, Zhang S, Liu X, Pan S, Li Y, Zhang L, He L, Niu Y
Oral diseases 2022 Apr;28(3):711-722
Oral diseases 2022 Apr;28(3):711-722
The Acetylation Modification of SP1 Regulates the Protein Stability in Silkworm.
Sun Z, Ma Y, Liu Y, Lv J, Wang D, You Z, Jiang C, Sheng Q, Nie Z
Applied biochemistry and biotechnology 2022 Apr;194(4):1621-1635
Applied biochemistry and biotechnology 2022 Apr;194(4):1621-1635
The transcription factor KLF14 regulates macrophage glycolysis and immune function by inhibiting HK2 in sepsis.
Yuan Y, Fan G, Liu Y, Liu L, Zhang T, Liu P, Tu Q, Zhang X, Luo S, Yao L, Chen F, Li J
Cellular & molecular immunology 2022 Apr;19(4):504-515
Cellular & molecular immunology 2022 Apr;19(4):504-515
Morusin enhances the antitumor activity of MAPK pathway inhibitors in BRAF-mutant melanoma by inhibiting the feedback activation of STAT3.
Zhao K, Dai Q, Wu J, Wei Z, Duan Y, Chen B
European journal of cancer (Oxford, England : 1990) 2022 Apr;165:58-70
European journal of cancer (Oxford, England : 1990) 2022 Apr;165:58-70
HECTD3 promotes gastric cancer progression by mediating the polyubiquitination of c-MYC.
Zhang G, Zhu Q, Yan X, Ci M, Zhao E, Hou J, Wan S, Lü M, Cui H
Cell death discovery 2022 Apr 9;8(1):185
Cell death discovery 2022 Apr 9;8(1):185
The m6A demethylase ALKBH5 promotes tumor progression by inhibiting RIG-I expression and interferon alpha production through the IKKε/TBK1/IRF3 pathway in head and neck squamous cell carcinoma.
Jin S, Li M, Chang H, Wang R, Zhang Z, Zhang J, He Y, Ma H
Molecular cancer 2022 Apr 9;21(1):97
Molecular cancer 2022 Apr 9;21(1):97
Aldehyde dehydrogenase 2 and PARP1 interaction modulates hepatic HDL biogenesis by LXRα-mediated ABCA1 expression.
Li L, Zhong S, Li R, Liang N, Zhang L, Xia S, Xu X, Chen X, Chen S, Tao Y, Yin H
JCI insight 2022 Apr 8;7(7)
JCI insight 2022 Apr 8;7(7)
SFN Enhanced the Radiosensitivity of Cervical Cancer Cells via Activating LATS2 and Blocking Rad51/MDC1 Recruitment to DNA Damage Site.
Wang S, Wang Y, Liu X, Yang Y, Wu S, Liu Y
Cancers 2022 Apr 8;14(8)
Cancers 2022 Apr 8;14(8)
Fumarate inhibits PTEN to promote tumorigenesis and therapeutic resistance of type2 papillary renal cell carcinoma.
Ge X, Li M, Yin J, Shi Z, Fu Y, Zhao N, Chen H, Meng L, Li X, Hu Z, Zhao X, Guo H, Qian X
Molecular cell 2022 Apr 7;82(7):1249-1260.e7
Molecular cell 2022 Apr 7;82(7):1249-1260.e7
Matrine injection inhibits pancreatic cancer growth via modulating carbonic anhydrases- a network pharmacology-based study with in vitro validation.
Xu PL, Cheng CS, Jiao JY, Chen H, Chen Z, Li P
Journal of ethnopharmacology 2022 Apr 6;287:114691
Journal of ethnopharmacology 2022 Apr 6;287:114691
M1 Macrophages Enhance Survival and Invasion of Oral Squamous Cell Carcinoma by Inducing GDF15-Mediated ErbB2 Phosphorylation.
Lv C, Li S, Zhao J, Yang P, Yang C
ACS omega 2022 Apr 5;7(13):11405-11414
ACS omega 2022 Apr 5;7(13):11405-11414
Tubastatin A Improves Post-Resuscitation Myocardial Dysfunction by Inhibiting NLRP3-Mediated Pyroptosis Through Enhancing Transcription Factor EB Signaling.
Xu J, Zhao X, Jiang X, He L, Wu X, Wang J, Chen Q, Li Y, Zhang M
Journal of the American Heart Association 2022 Apr 5;11(7):e024205
Journal of the American Heart Association 2022 Apr 5;11(7):e024205
Reversal of Lipid Metabolism Dysregulation by Selenium and Folic Acid Co-Supplementation to Mitigate Pathology in Alzheimer's Disease.
Zhang ZH, Cao XC, Peng JY, Huang SL, Chen C, Jia SZ, Ni JZ, Song GL
Antioxidants (Basel, Switzerland) 2022 Apr 24;11(5)
Antioxidants (Basel, Switzerland) 2022 Apr 24;11(5)
Targeting DRD2 by the antipsychotic drug, penfluridol, retards growth of renal cell carcinoma via inducing stemness inhibition and autophagy-mediated apoptosis.
Tung MC, Lin YW, Lee WJ, Wen YC, Liu YC, Chen JQ, Hsiao M, Yang YC, Chien MH
Cell death & disease 2022 Apr 23;13(4):400
Cell death & disease 2022 Apr 23;13(4):400
Two distinct males absent on the first (MOF)-containing histone acetyltransferases are involved in the epithelial-mesenchymal transition in different ways in human cells.
Wei T, Liu H, Zhu H, Chen W, Wu T, Bai Y, Zhang X, Miao Y, Wang F, Cai Y, Jin J
Cellular and molecular life sciences : CMLS 2022 Apr 13;79(5):238
Cellular and molecular life sciences : CMLS 2022 Apr 13;79(5):238
Aberrant expression of PROS1 correlates with human papillary thyroid cancer progression.
Wang J, Lei M, Xu Z
PeerJ 2021;9:e11813
PeerJ 2021;9:e11813
High PHD Finger Protein 19 (PHF19) expression predicts poor prognosis in colorectal cancer: a retrospective study.
Li P, Sun J, Ruan Y, Song L
PeerJ 2021;9:e11551
PeerJ 2021;9:e11551
Screening and identification of endometrial proteins as novel potential biomarkers for repeated implantation failure.
Wang C, Feng Y, Zhou WJ, Cheng ZJ, Jiang MY, Zhou Y, Fei XY
PeerJ 2021;9:e11009
PeerJ 2021;9:e11009
MicroRNA-222 Transferred From Semen Extracellular Vesicles Inhibits Sperm Apoptosis by Targeting BCL2L11.
Ding Y, Ding N, Zhang Y, Xie S, Huang M, Ding X, Dong W, Zhang Q, Jiang L
Frontiers in cell and developmental biology 2021;9:736864
Frontiers in cell and developmental biology 2021;9:736864
Macrophage-Mediated Bone Formation in Scaffolds Modified With MSC-Derived Extracellular Matrix Is Dependent on the Migration Inhibitory Factor Signaling Pathway.
Deng M, Tan J, Dai Q, Luo F, Xu J
Frontiers in cell and developmental biology 2021;9:714011
Frontiers in cell and developmental biology 2021;9:714011
Cardioprotective Role of SIRT5 in Response to Acute Ischemia Through a Novel Liver-Cardiac Crosstalk Mechanism.
Zhou B, Xiao M, Hu H, Pei X, Xue Y, Miao G, Wang J, Li W, Du Y, Zhang P, Wei T
Frontiers in cell and developmental biology 2021;9:687559
Frontiers in cell and developmental biology 2021;9:687559
Urea as a By-Product of Ammonia Metabolism Can Be a Potential Serum Biomarker of Hepatocellular Carcinoma.
Bai C, Wang H, Dong D, Li T, Yu Z, Guo J, Zhou W, Li D, Yan R, Wang L, Wang Z, Li Y, Ren L
Frontiers in cell and developmental biology 2021;9:650748
Frontiers in cell and developmental biology 2021;9:650748
RBM14 Modulates Tubulin Acetylation and Regulates Spindle Morphology During Meiotic Maturation in Mouse Oocytes.
Qin H, Qu Y, Yuan YF, Li YY, Qiao J
Frontiers in cell and developmental biology 2021;9:635728
Frontiers in cell and developmental biology 2021;9:635728
Impaired Retrograde Transport Due to Lack of TBC1D5 Contributes to the Trafficking Defect of Lysosomal Cathepsins in Ischemic/Hypoxic Cardiomyocytes.
Cui L, Zhang Q, Huang Y, Yang L, Zhang J, Jiang X, Jia J, Lv Y, Zhang D, Huang Y
Frontiers in cardiovascular medicine 2021;8:796254
Frontiers in cardiovascular medicine 2021;8:796254
S-Propargyl-Cysteine Attenuates Diabetic Cardiomyopathy in db/db Mice Through Activation of Cardiac Insulin Receptor Signaling.
Li Y, Xie KF, Chang YH, Wang C, Chen Y, Wang MJ, Zhu YC
Frontiers in cardiovascular medicine 2021;8:737191
Frontiers in cardiovascular medicine 2021;8:737191
Cold-Induced RNA-Binding Protein Promotes Glucose Metabolism and Reduces Apoptosis by Increasing AKT Phosphorylation in Mouse Skeletal Muscle Under Acute Cold Exposure.
Liu Y, Liu P, Hu Y, Cao Y, Lu J, Yang Y, Lv H, Lian S, Xu B, Li S
Frontiers in molecular biosciences 2021;8:685993
Frontiers in molecular biosciences 2021;8:685993
Secreted Frizzled-Related Protein 5 Protects Against Cardiac Rupture and Improves Cardiac Function Through Inhibiting Mitochondrial Dysfunction.
Huang X, Yan Y, Zheng W, Ma Y, Wang X, Gong W, Nie S
Frontiers in cardiovascular medicine 2021;8:682409
Frontiers in cardiovascular medicine 2021;8:682409
Network-Based Expression Analyses and Experimental Verifications Reveal the Involvement of STUB1 in Acute Kidney Injury.
Shi Y, Chen G, Teng J
Frontiers in molecular biosciences 2021;8:655361
Frontiers in molecular biosciences 2021;8:655361
TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer.
Yang B, Chen J, Teng Y
Journal of immunology research 2021;2021:9994004
Journal of immunology research 2021;2021:9994004
Anticancer Action of Xiaoxianxiong Tang in Non-Small Cell Lung Cancer by Pharmacological Analysis and Experimental Validation.
Ding R, Jiao L, Sang S, Yin Y, Wang Y, Gong Y, Xu L, Bi L
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9930082
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9930082
ZC3H15 Correlates with a Poor Prognosis and Tumor Progression in Melanoma.
Li Q, Hou J, Guo C, Zhang Y, Liu L, Hu H, Shi S, Ji Y, Guo L, Shi Y, Liu Y, Cui H
BioMed research international 2021;2021:8305299
BioMed research international 2021;2021:8305299
Brusatol Inhibits Tumor Growth and Increases the Efficacy of Cabergoline against Pituitary Adenomas.
Wu Z, Xu Y, Xu J, Lu J, Cai L, Li Q, Wang C, Su Z
Oxidative medicine and cellular longevity 2021;2021:6696015
Oxidative medicine and cellular longevity 2021;2021:6696015
Glucagon-like Peptide-1 Improves Fatty Liver and Enhances Thermogenesis in Brown Adipose Tissue via Inhibiting BMP4-Related Signaling Pathway in High-Fat-Diet-Induced Obese Mice.
Wang X, Ma B, Chen J, You H, Sheng C, Yang P, Qu S
International journal of endocrinology 2021;2021:6620289
International journal of endocrinology 2021;2021:6620289
USP1 Promotes GC Metastasis via Stabilizing ID2.
Li N, Wu L, Zuo X, Luo H, Sheng Y, Yan J
Disease markers 2021;2021:3771990
Disease markers 2021;2021:3771990
Folic Acid Protects Melanocytes from Oxidative Stress via Activation of Nrf2 and Inhibition of HMGB1.
Du P, Zhang S, Li S, Yang Y, Kang P, Chen J, Gao T, Li C, Zhang Q, Zhang W
Oxidative medicine and cellular longevity 2021;2021:1608586
Oxidative medicine and cellular longevity 2021;2021:1608586
Generation of VEGF knock-in Cashmere goat via the CRISPR/Cas9 system.
Hu X, Hao F, Li X, Xun Z, Gao Y, Ren B, Cang M, Liang H, Liu D
International journal of biological sciences 2021;17(4):1026-1040
International journal of biological sciences 2021;17(4):1026-1040
MAD2B-mediated cell cycle reentry of podocytes is involved in the pathogenesis of FSGS.
Bao D, Su H, Lei CT, Tang H, Ye C, Xiong W, He FF, Lin JH, Hammes HP, Zhang C
International journal of biological sciences 2021;17(15):4396-4408
International journal of biological sciences 2021;17(15):4396-4408
A Novel Hydrogen Sulfide Donor Reduces Pilocarpine-Induced Status Epilepticus and Regulates Microglial Inflammatory Profile.
Liu Z, Zhu Z, He Y, Kang Q, Li F, Zhang W, He Y, Lin Y, Huang B, Mo M, Xu P, Zhu X
Frontiers in cellular neuroscience 2021;15:780447
Frontiers in cellular neuroscience 2021;15:780447
Bardoxolone-Methyl Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in vitro and Alleviates Osteoarthritis in vivo.
Pang Z, Jiang Z, Zhu R, Song C, Tang H, Cao L, Guo C
Drug design, development and therapy 2021;15:3735-3747
Drug design, development and therapy 2021;15:3735-3747
A-FABP-PTEN/AKT Regulates Insulin Resistance in Preadipocyte Cell 3T3-L1 Cells.
Wu R, Wang H, Huangfu J, Xiao R
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2103-2110
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2103-2110
Irradiation-Induced Activated Microglia Affect Brain Metastatic Colonization of NSCLC Cells via miR-9/CDH1 Axis.
Jin Y, Kang Y, Peng X, Yang L, Li Q, Mei Q, Chen X, Hu G, Tang Y, Yuan X
OncoTargets and therapy 2021;14:1911-1922
OncoTargets and therapy 2021;14:1911-1922
STAT5 inhibitor attenuates atherosclerosis via inhibition of inflammation: the role of STAT5 in atherosclerosis.
Wang X, Ding X, Yan J, Lu Z, Cao H, Ni X, Ying Y
American journal of translational research 2021;13(3):1422-1431
American journal of translational research 2021;13(3):1422-1431
Sevoflurane prevents pulmonary vascular remodeling and right ventricular dysfunction in pulmonary arterial hypertension in rats.
Zhai W, Li Y, Luo Y, Gao W, Liu S, Han J, Geng J
American journal of translational research 2021;13(10):11302-11315
American journal of translational research 2021;13(10):11302-11315
Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.
Wang L, Huang Y, Liu C, Guo M, Ma Z, He J, Wang A, Sun X, Liu Z
Journal of Cancer 2021;12(3):860-873
Journal of Cancer 2021;12(3):860-873
PFKP Activation Ameliorates Foot Process Fusion in Podocytes in Diabetic Kidney Disease.
Zhang Z, Liang W, Luo Q, Hu H, Yang K, Hu J, Chen Z, Zhu J, Feng J, Zhu Z, Chi Q, Ding G
Frontiers in endocrinology 2021;12:797025
Frontiers in endocrinology 2021;12:797025
Screening of a Small Molecule Compound Library Identifies Toosendanin as an Inhibitor Against Bunyavirus and SARS-CoV-2.
Li S, Ye M, Chen Y, Zhang Y, Li J, Liu W, Li H, Peng K
Frontiers in pharmacology 2021;12:735223
Frontiers in pharmacology 2021;12:735223
Pharmacological Inhibition of HMGB1 Prevents Muscle Wasting.
Li L, Liu H, Tao W, Wen S, Fu X, Yu S
Frontiers in pharmacology 2021;12:731386
Frontiers in pharmacology 2021;12:731386
DMRT2 Interacts With FXR and Improves Insulin Resistance in Adipocytes and a Mouse Model.
Tao J, Yu XL, Yuan YJ, Shen X, Liu J, Gu PP, Wang Z, Ma YT, Li GQ
Frontiers in endocrinology 2021;12:723623
Frontiers in endocrinology 2021;12:723623
Exploring the Prognostic Value, Immune Implication and Biological Function of H2AFY Gene in Hepatocellular Carcinoma.
Huang Y, Huang S, Ma L, Wang Y, Wang X, Xiao L, Qin W, Li L, Yuan X
Frontiers in immunology 2021;12:723293
Frontiers in immunology 2021;12:723293
Identification of a Novel Epigenetic Signature CHFR as a Potential Prognostic Gene Involved in Metastatic Clear Cell Renal Cell Carcinoma.
Chen X, Lin J, Chen Q, Liao X, Wang T, Li S, Mao L, Li Z
Frontiers in genetics 2021;12:720979
Frontiers in genetics 2021;12:720979
Effect of Xanthium Strumarium on HIV-1 5'-LTR Transcriptional Activity and Viral Reactivation in Latently Infected Cells.
Chen CJ, Chiu ML, Hung CH, Liang WM, Ho MW, Lin TH, Liu X, Tsang H, Liao CC, Huang SM, Wu YF, Wu YC, Li TM, Tsai FJ, Lin YJ
Frontiers in pharmacology 2021;12:720821
Frontiers in pharmacology 2021;12:720821
Activation of STING Pathway Contributed to Cisplatin-Induced Cardiac Dysfunction via Promoting the Activation of TNF-α-AP-1 Signal Pathway.
Wang L, Zhang S, Han J, Nie X, Qi Y, Han Y, Chen X, He C
Frontiers in pharmacology 2021;12:711238
Frontiers in pharmacology 2021;12:711238
Comprehensive Bioinformatics Analysis Identifies POLR2I as a Key Gene in the Pathogenesis of Hypertensive Nephropathy.
You S, Xu J, Wu B, Wu S, Zhang Y, Sun Y, Zhang N
Frontiers in genetics 2021;12:698570
Frontiers in genetics 2021;12:698570
IL20RA signaling enhances stemness and promotes the formation of an immunosuppressive microenvironment in breast cancer.
Gao W, Wen H, Liang L, Dong X, Du R, Zhou W, Zhang X, Zhang C, Xiang R, Li N
Theranostics 2021;11(6):2564-2580
Theranostics 2021;11(6):2564-2580
Glycosylation of Siglec15 promotes immunoescape and tumor growth.
Wang YL, Wei MB, Zhao WW, Feng LL, Yin XK, Bai SM, Wan XB, Hung MC, Zou AZ, Wang MH, Zheng J, Qin C, Fan XJ
American journal of cancer research 2021;11(5):2291-2302
American journal of cancer research 2021;11(5):2291-2302
Cordycepin inhibits the proliferation of malignant peripheral nerve sheath tumor cells through the p53/Sp1/tubulin pathway.
Lee MJ, Lee JC, Hsieh JH, Lin MY, Shih IA, You HL, Wang K
American journal of cancer research 2021;11(4):1247-1266
American journal of cancer research 2021;11(4):1247-1266
Pan-Cancer Analyses Reveal Oncogenic Role and Prognostic Value of F-Box Only Protein 22.
Chen S, Ma S, Yan J, Wang H, Ding B, Guo Z, Ma Y, Chen X, Wang Y
Frontiers in oncology 2021;11:790912
Frontiers in oncology 2021;11:790912
Modulated TRPC1 Expression Predicts Sensitivity of Breast Cancer to Doxorubicin and Magnetic Field Therapy: Segue Towards a Precision Medicine Approach.
Tai YK, Chan KKW, Fong CHH, Ramanan S, Yap JLY, Yin JN, Yip YS, Tan WR, Koh APF, Tan NS, Chan CW, Huang RYJ, Li JZ, Fröhlich J, Franco-Obregón A
Frontiers in oncology 2021;11:783803
Frontiers in oncology 2021;11:783803
Potential Role of SWI/SNF Complex Subunit Actin-Like Protein 6A in Cervical Cancer.
Wang Q, Cao Z, Wei Y, Zhang J, Cheng Z
Frontiers in oncology 2021;11:724832
Frontiers in oncology 2021;11:724832
Periodontal Pathogens Promote Oral Squamous Cell Carcinoma by Regulating ATR and NLRP3 Inflammasome.
Yao Y, Shen X, Zhou M, Tang B
Frontiers in oncology 2021;11:722797
Frontiers in oncology 2021;11:722797
Oleic Acid and Insulin as Key Characteristics of T2D Promote Colorectal Cancer Deterioration in Xenograft Mice Revealed by Functional Metabolomics.
Zhang Y, Wang D, Lv B, Hou X, Liu Q, Liao C, Xu R, Zhang Y, Xu F, Zhang P
Frontiers in oncology 2021;11:685059
Frontiers in oncology 2021;11:685059
PGK1 Is a Key Target for Anti-Glycolytic Therapy of Ovarian Cancer: Based on the Comprehensive Analysis of Glycolysis-Related Genes.
Gou R, Hu Y, Liu O, Dong H, Gao L, Wang S, Zheng M, Li X, Lin B
Frontiers in oncology 2021;11:682461
Frontiers in oncology 2021;11:682461
Identification METTL18 as a Potential Prognosis Biomarker and Associated With Immune Infiltrates in Hepatocellular Carcinoma.
Li TH, Qin C, Zhao BB, Cao HT, Yang XY, Wang YY, Li ZR, Zhou XT, Wang WB
Frontiers in oncology 2021;11:665192
Frontiers in oncology 2021;11:665192
Targeting Mutated p53 Dependency in Triple-Negative Breast Cancer Cells Through CDK7 Inhibition.
Peng J, Yang M, Bi R, Wang Y, Wang C, Wei X, Zhang Z, Xie X, Wei W
Frontiers in oncology 2021;11:664848
Frontiers in oncology 2021;11:664848
Dihydrocapsaicin Inhibits Cell Proliferation and Metastasis in Melanoma via Down-regulating β-Catenin Pathway.
Shi S, Li C, Zhang Y, Deng C, Liu W, Du J, Li Q, Ji Y, Guo L, Liu L, Hu H, Liu Y, Cui H
Frontiers in oncology 2021;11:648052
Frontiers in oncology 2021;11:648052
Salmonella Effector SpvB Inhibits NF-κB Activity via KEAP1-Mediated Downregulation of IKKβ.
Yang S, Deng Q, Sun L, Zhu Y, Dong K, Wu S, Huang R, Li Y
Frontiers in cellular and infection microbiology 2021;11:641412
Frontiers in cellular and infection microbiology 2021;11:641412
Loss of TARBP2 Drives the Progression of Hepatocellular Carcinoma via miR-145-SERPINE1 Axis.
Li LM, Chen C, Ran RX, Huang JT, Sun HL, Zeng C, Zhang Z, Zhang W, Liu SM
Frontiers in oncology 2021;11:620912
Frontiers in oncology 2021;11:620912
Pterostilbene and its nicotinate derivative ameliorated vascular endothelial senescence and elicited endothelium-dependent relaxations via activation of sirtuin 1.
Zhang L, Zheng J, Tie X, Lin T, Yang W, Li Z, Zou Y, Guan G, Liu P, Luo W, Li Z
Canadian journal of physiology and pharmacology 2021 Sep;99(9):900-909
Canadian journal of physiology and pharmacology 2021 Sep;99(9):900-909
Inhibitory effect of HTLV-1 infection on the production of B-cell activating factors in established follicular dendritic cell-like cells.
Takatani A, Nakamura H, Furukawa K, Endo Y, Umeda M, Shimizu T, Nishihata SY, Kitaoka K, Nakamura T, Kawakami A
Immunity, inflammation and disease 2021 Sep;9(3):777-791
Immunity, inflammation and disease 2021 Sep;9(3):777-791
Lower levels of tubulin alpha 1b in the frontal pole in schizophrenia supports a role for changed cytoskeletal dynamics in the aetiology of the disorder.
Snelleksz M, Dean B
Psychiatry research 2021 Sep;303:114096
Psychiatry research 2021 Sep;303:114096
SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination.
Zhang Z, Zheng Y, Niu Z, Zhang B, Wang C, Yao X, Peng H, Franca DN, Wang Y, Zhu Y, Su Y, Tang M, Jiang X, Ren H, He M, Wang Y, Gao L, Zhao P, Shi H, Chen Z, Wang X, Piacentini M, Bian X, Melino G, Liu L, Huang H, Sun Q
Cell death and differentiation 2021 Sep;28(9):2765-2777
Cell death and differentiation 2021 Sep;28(9):2765-2777
The inhibitory effect of the deubiquitinase cylindromatosis (CYLD) on inflammatory responses in human gingival fibroblasts.
Fu YW, Li L, Wang XQ, Zhou Y, Zhu LF, Mei YM, Xu Y
Oral diseases 2021 Sep;27(6):1487-1497
Oral diseases 2021 Sep;27(6):1487-1497
Demethylzeylasteral inhibits proliferation, migration, and invasion through FBXW7/c-Myc axis in gastric cancer.
Li Y, Su Y, Zhao Y, Hu X, Zhao G, He J, Wan S, Lü M, Cui H
MedComm 2021 Sep;2(3):467-480
MedComm 2021 Sep;2(3):467-480
[ANXA8 Regulates Proliferation of Human Non-Small Lung Cancer Cells A549 via EGFR-AKT-mTOR Signaling Pathway].
Zhou GZ, Sun YH, Shi YY, Zhang Q, Zhang L, Cui LQ, Sun GC
Molekuliarnaia biologiia 2021 Sep-Oct;55(5):870-880
Molekuliarnaia biologiia 2021 Sep-Oct;55(5):870-880
CDC20 promotes bone formation via APC/C dependent ubiquitination and degradation of p65.
Du Y, Zhang M, Liu X, Li Z, Hu M, Tian Y, Lv L, Zhang X, Liu Y, Zhang P, Zhou Y
EMBO reports 2021 Sep 6;22(9):e52576
EMBO reports 2021 Sep 6;22(9):e52576
PEX5 prevents cardiomyocyte hypertrophy via suppressing the redox-sensitive signaling pathways MAPKs and STAT3.
Wang M, Li J, Ding Y, Cai S, Li Z, Liu P
European journal of pharmacology 2021 Sep 5;906:174283
European journal of pharmacology 2021 Sep 5;906:174283
Silencing ZIC2 abrogates tumorigenesis and anoikis resistance of non-small cell lung cancer cells by inhibiting Src/FAK signaling.
Liu A, Xie H, Li R, Ren L, Yang B, Dai L, Lu W, Liu B, Ren D, Zhang X, Chen Q, Huang Y, Shi K
Molecular therapy oncolytics 2021 Sep 24;22:195-208
Molecular therapy oncolytics 2021 Sep 24;22:195-208
Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome.
Peoples JN, Ghazal N, Duong DM, Hardin KR, Manning JR, Seyfried NT, Faundez V, Kwong JQ
American journal of physiology. Cell physiology 2021 Sep 1;321(3):C519-C534
American journal of physiology. Cell physiology 2021 Sep 1;321(3):C519-C534
The protective effect of isoflurane pretreatment on liver IRI by suppressing noncanonical pyroptosis of liver macrophages.
Lu J, Wang X, Feng Z, Chen Y, Wen D, Liu Z
International immunopharmacology 2021 Oct;99:107977
International immunopharmacology 2021 Oct;99:107977
Effects of andrographolide on renal tubulointersticial injury and fibrosis. Evidence of its mechanism of action.
Liu W, Liang L, Zhang Q, Li Y, Yan S, Tang T, Ren Y, Mo J, Liu F, Chen X, Lan T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153650
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153650
Assembly of Cytoplasmic Stress Granules in Placentas in Women with Preeclampsia.
Ma C, Li C, Shao S, Li C, Yu S, Zhao L, Li Y, Zhao S
Reproductive sciences (Thousand Oaks, Calif.) 2021 Oct;28(10):2869-2877
Reproductive sciences (Thousand Oaks, Calif.) 2021 Oct;28(10):2869-2877
Oxidized phospholipids on alkyl-amide scaffold demonstrate anti-endotoxin and endothelial barrier-protective properties.
Oskolkova OV, Hodzic A, Karki P, Gesslbauer B, Ke Y, Hofer DC, Bogner-Strauss JG, Galano JM, Oger C, Birukova A, Durand T, Birukov K, Bochkov V
Free radical biology & medicine 2021 Oct;174:264-271
Free radical biology & medicine 2021 Oct;174:264-271
Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases.
Arnould H, Baudouin V, Baudry A, Ribeiro LW, Ardila-Osorio H, Pietri M, Caradeuc C, Soultawi C, Williams D, Alvarez M, Crozet C, Djouadi F, Laforge M, Bertho G, Kellermann O, Launay JM, Schmitt-Ulms G, Schneider B
PLoS pathogens 2021 Oct;17(10):e1009991
PLoS pathogens 2021 Oct;17(10):e1009991
Deacetylation of BmAda3 is required for cell apoptosis caused by Bombyx mori nucleopolyhedrovirus infection.
Zhu Y, Hu M, Ngowo J, Gao X, Chen X, Yan H, Yu W
Archives of insect biochemistry and physiology 2021 Oct;108(2):e21838
Archives of insect biochemistry and physiology 2021 Oct;108(2):e21838
Vitellogenin 2 promotes muscle development and stimulates the browning of white fat.
Li Y, Sun X, Bai Y, Ji Y, Ren H, Yu X, Yan Y, He X, Dong Y, Zhang L, Luo X, Wang H
Aging 2021 Oct 5;13(19):22985-23003
Aging 2021 Oct 5;13(19):22985-23003
Design, Synthesis, and Biological Evaluation of Icaritin Derivatives as Novel Putative DEPTOR Inhibitors for Multiple Myeloma Treatment.
Hou Y, Kuang W, Min W, Liu Z, Zhang F, Yuan K, Wang X, Sun C, Cheng H, Wang L, Xiao Y, Pu S, Xin GZ, Yang P
Journal of medicinal chemistry 2021 Oct 28;64(20):14942-14954
Journal of medicinal chemistry 2021 Oct 28;64(20):14942-14954
Folic Acid-Appended Hydroxypropyl-β-Cyclodextrin Exhibits Potent Antitumor Activity in Chronic Myeloid Leukemia Cells via Autophagic Cell Death.
Hoshiko T, Kubota Y, Onodera R, Higashi T, Yokoo M, Motoyama K, Kimura S
Cancers 2021 Oct 28;13(21)
Cancers 2021 Oct 28;13(21)
19-Hydroxybufalin inhibits non-small cell lung cancer cell proliferation and promotes cell apoptosis via the Wnt/β-catenin pathway.
Yu W, Zhang X, Zhang W, Xiong M, Lin Y, Chang M, Xu L, Lu Y, Liu Y, Zhang J
Experimental hematology & oncology 2021 Oct 25;10(1):48
Experimental hematology & oncology 2021 Oct 25;10(1):48
CHD8 safeguards early neuroectoderm differentiation in human ESCs and protects from apoptosis during neurogenesis.
Ding S, Lan X, Meng Y, Yan C, Li M, Li X, Chen J, Jiang W
Cell death & disease 2021 Oct 22;12(11):981
Cell death & disease 2021 Oct 22;12(11):981
Stem Cell Factor SOX2 Confers Ferroptosis Resistance in Lung Cancer via Upregulation of SLC7A11.
Wang X, Chen Y, Wang X, Tian H, Wang Y, Jin J, Shan Z, Liu Y, Cai Z, Tong X, Luan Y, Tan X, Luan B, Ge X, Ji H, Jiang X, Wang P
Cancer research 2021 Oct 15;81(20):5217-5229
Cancer research 2021 Oct 15;81(20):5217-5229
Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer.
Zhang J, Zou L, Shi D, Liu J, Zhang J, Zhao R, Wang G, Zhang L, Ouyang L, Liu B
Journal of medicinal chemistry 2021 Oct 14;64(19):14192-14216
Journal of medicinal chemistry 2021 Oct 14;64(19):14192-14216
Bortezomib potentiates antitumor activity of mitoxantrone through dampening Wnt/β-catenin signal pathway in prostate cancer cells.
Zhang Y, Liu Q, Wei W, Zhang G, Yan S, Dai R, Sun Y, Su D, Lv S, Xia Y, Li J, Li C
BMC cancer 2021 Oct 13;21(1):1101
BMC cancer 2021 Oct 13;21(1):1101
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
Wang Y, Yuan J, Yu X, Liu X, Tan C, Chen Y, Xu T
Cell death & disease 2021 Oct 12;12(10):936
Cell death & disease 2021 Oct 12;12(10):936
ZFC3H1 prevents RNA trafficking into nuclear speckles through condensation.
Wang Y, Fan J, Wang J, Zhu Y, Xu L, Tong D, Cheng H
Nucleic acids research 2021 Oct 11;49(18):10630-10643
Nucleic acids research 2021 Oct 11;49(18):10630-10643
Effects and Mechanisms of Synaptotagmin-7 in the Hippocampus on Cognitive Impairment in Aging Mice.
Xie Y, Zhi K, Meng X
Molecular neurobiology 2021 Nov;58(11):5756-5771
Molecular neurobiology 2021 Nov;58(11):5756-5771
A novel CCDC39 mutation causes multiple morphological abnormalities of the flagella in a primary ciliary dyskinesia patient.
Chen D, Liang Y, Li J, Zhang X, Zheng R, Wang X, Zhang H, Shen Y
Reproductive biomedicine online 2021 Nov;43(5):920-930
Reproductive biomedicine online 2021 Nov;43(5):920-930
C23 gene regulates the nucleolin structure and biosynthesis of ribosomes in bovine intraspecific and interspecific somatic cell nuclear transfer embryos.
Su G, Wang L, Gao G, Wu S, Yang L, Wu M, Liu X, Yang M, Wei Z, Bai C, Li G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21993
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21993
Inhibition of MAD2B alleviates venous neointimal formation by suppressing VSMCs proliferation and migration.
Song AN, Yin XJ, Gao P, Tang H, Meng XF, Zhang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21959
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21959
Perfluorooctane sulfonate induces autophagy-dependent lysosomal membrane permeabilization by weakened interaction between tyrosinated alpha-tubulin and spinster 1.
Dong Z, Qiu T, Zhang J, Sha S, Han X, Kang J, Shi X, Sun X, Jiang L, Yang G, Yao X, Ma Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112540
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112540
WIPI-1 inhibits metastasis and tumour growth via the WIPI-1-TRIM21 axis and MYC regulation in nasopharyngeal carcinoma.
Zhao Y, Li WF, Li QJ, He SW, He QM, Long LF, Liu N, Ma J
Oral oncology 2021 Nov;122:105576
Oral oncology 2021 Nov;122:105576
Yeast Two-Hybrid Screen Identifies PKA-Riα Interacting Proteins during Mouse Spermiogenesis.
Shi K, Yang L, Zhuang X, Zhang L, Qi H
Genes 2021 Nov 30;12(12)
Genes 2021 Nov 30;12(12)
Cilia locally synthesize proteins to sustain their ultrastructure and functions.
Hao K, Chen Y, Yan X, Zhu X
Nature communications 2021 Nov 30;12(1):6971
Nature communications 2021 Nov 30;12(1):6971
Sesquiterpene Lactones from Sigesbeckia glabrescens Possessing Potent Anti-inflammatory Activity by Directly Binding to IKKα/β.
Gao X, Shen X, Zheng Y, Yang L, Zhang X, Hu G, Jia J, Wang A
Journal of natural products 2021 Nov 26;84(11):2808-2821
Journal of natural products 2021 Nov 26;84(11):2808-2821
Programmed cell death 5 improves skeletal muscle insulin resistance by inhibiting IRS-1 ubiquitination through stabilization of MDM2.
Li B, Ye J, Liu R, Weng L, Cao Y, Jia S, Xu C, Liu Y, Yan S, Zheng M
Life sciences 2021 Nov 15;285:119918
Life sciences 2021 Nov 15;285:119918
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.
Yoo JS, Sasaki M, Cho SX, Kasuga Y, Zhu B, Ouda R, Orba Y, de Figueiredo P, Sawa H, Kobayashi KS
Nature communications 2021 Nov 15;12(1):6602
Nature communications 2021 Nov 15;12(1):6602
Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation.
Zheng L, Ren R, Sun X, Zou Y, Shi Y, Di B, Niu MM
Journal of medicinal chemistry 2021 Nov 11;64(21):15702-15715
Journal of medicinal chemistry 2021 Nov 11;64(21):15702-15715
The deubiquitinating enzyme ATXN3 promotes the progression of anaplastic thyroid carcinoma by stabilizing EIF5A2.
Zhuang S, Xie J, Zhen J, Guo L, Hong Z, Li F, Xu D
Molecular and cellular endocrinology 2021 Nov 1;537:111440
Molecular and cellular endocrinology 2021 Nov 1;537:111440
TMEM98, a novel secretory protein, promotes endothelial cell adhesion as well as vascular smooth muscle cell proliferation and migration.
Li M, Zhu H, Hu X, Gao F, Hu X, Cui Y, Wei X, Xie C, Lv G, Zhao Y, Gao Y
Canadian journal of physiology and pharmacology 2021 May;99(5):536-548
Canadian journal of physiology and pharmacology 2021 May;99(5):536-548
W2476 represses TXNIP transcription via dephosphorylation of FOXO1 at Ser319.
Zhong L, Liu Q, Liu Q, Zhang S, Cao Y, Yang D, Wang MW
Chemical biology & drug design 2021 May;97(5):1089-1099
Chemical biology & drug design 2021 May;97(5):1089-1099
Heme supplementation ameliorates lupus nephritis through rectifying the disorder of splenocytes and alleviating renal inflammation and oxidative damage.
Wu B, Wu Y, Fan C, Feng C, Wang H, Bai F, Zuo J, Tang W
International immunopharmacology 2021 May;94:107482
International immunopharmacology 2021 May;94:107482
Trojan Horse Delivery of 4,4'-Dimethoxychalcone for Parkinsonian Neuroprotection.
Zhang W, Chen H, Ding L, Gong J, Zhang M, Guo W, Xu P, Li S, Zhang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(9):2004555
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(9):2004555
UFL1 regulates milk protein and fat synthesis-related gene expression of bovine mammary epithelial cells probably via the mTOR signaling pathway.
Li C, Li L, Ali I, Kuang M, Wang X, Wang G
In vitro cellular & developmental biology. Animal 2021 May;57(5):550-559
In vitro cellular & developmental biology. Animal 2021 May;57(5):550-559
Role of epigenetic m(6) A RNA methylation in vascular development: mettl3 regulates vascular development through PHLPP2/mTOR-AKT signaling.
Parial R, Li H, Li J, Archacki S, Yang Z, Wang IZ, Chen Q, Xu C, Wang QK
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21465
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21465
33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways.
Guo C, Li N, Dong C, Wang L, Li Z, Liu Q, Ma Q, Greenaway FT, Tian Y, Hao L, Liu S, Sun MZ
Journal of advanced research 2021 May;30:85-102
Journal of advanced research 2021 May;30:85-102
Nicotine-derived NNK induces the stemness enrichment of CRC cells through regulating the balance of DUSP4-ERK1/2 feedback loop.
Chen Y, Wang Q, Cao L, Tang Y, Yao M, Bi H, Huang Y, Sun G, Song J
Ecotoxicology and environmental safety 2021 May;214:112057
Ecotoxicology and environmental safety 2021 May;214:112057
mTOR regulates PRMT1 expression and mitochondrial mass through STAT1 phosphorylation in hepatic cell.
Zhang X, Li L, Li Y, Li Z, Zhai W, Sun Q, Yang X, Roth M, Lu S
Biochimica et biophysica acta. Molecular cell research 2021 May;1868(6):119017
Biochimica et biophysica acta. Molecular cell research 2021 May;1868(6):119017
Ubash3b promotes TPA-mediated suppression of leukemogenesis through accelerated downregulation of PKCδ protein.
Yao Y, Liu W, Gajendran B, Wang C, Zacksenhaus E, Sample KM, Varier KM, Hao X, Ben-David Y
Biochimie 2021 May;184:8-17
Biochimie 2021 May;184:8-17
Aging-associated lncRNAs are evolutionarily conserved and participate in NFκB signaling.
Cai D, Han JJ
Nature aging 2021 May;1(5):438-453
Nature aging 2021 May;1(5):438-453
Pathogenesis of acephalic spermatozoa syndrome caused by SUN5 variant.
Zhang D, Huang WJ, Chen GY, Dong LH, Tang Y, Zhang H, Li QQ, Mei XY, Wang ZH, Lan FH
Molecular human reproduction 2021 May 8;27(5)
Molecular human reproduction 2021 May 8;27(5)
Ggps1 deficiency in the uterus results in dystocia by disrupting uterine contraction.
Sang YJ, Wang Q, Zheng F, Hua Y, Wang XY, Zhang JZ, Li K, Wang HQ, Zhao Y, Zhu MS, Sun HX, Li CJ
Journal of molecular cell biology 2021 May 7;13(2):116-127
Journal of molecular cell biology 2021 May 7;13(2):116-127
Pragmatic recruitment of memantine as the capping group for the design of HDAC inhibitors: A preliminary attempt to unravel the enigma of glioblastoma.
Nepali K, Hsu TI, Hsieh CM, Lo WL, Lai MJ, Hsu KC, Lin TE, Chuang JY, Liou JP
European journal of medicinal chemistry 2021 May 5;217:113338
European journal of medicinal chemistry 2021 May 5;217:113338
Model-based analysis uncovers mutations altering autophagy selectivity in human cancer.
Han Z, Zhang W, Ning W, Wang C, Deng W, Li Z, Shang Z, Shen X, Liu X, Baba O, Morita T, Chen L, Xue Y, Jia D
Nature communications 2021 May 31;12(1):3258
Nature communications 2021 May 31;12(1):3258
Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus.
Wang Q, Xin Q, Shang W, Wan W, Xiao G, Zhang LK
Viruses 2021 May 25;13(6)
Viruses 2021 May 25;13(6)
Genistein suppresses allergic contact dermatitis through regulating the MAP2K2/ERK pathway.
Xu J, Xiong H, Zhao Z, Luo M, Ju Y, Yang G, Mei Z
Food & function 2021 May 21;12(10):4556-4569
Food & function 2021 May 21;12(10):4556-4569
HSP90-dependent PUS7 overexpression facilitates the metastasis of colorectal cancer cells by regulating LASP1 abundance.
Song D, Guo M, Xu S, Song X, Bai B, Li Z, Chen J, An Y, Nie Y, Wu K, Wang S, Zhao Q
Journal of experimental & clinical cancer research : CR 2021 May 14;40(1):170
Journal of experimental & clinical cancer research : CR 2021 May 14;40(1):170
H(+)/Cl(‑) exchange transporter 7 promotes lysosomal acidification‑mediated autophagy in mouse cardiomyocytes.
Lin J, Wei J, Lv Y, Zhang X, Yi RF, Dai C, Zhang Q, Jia J, Zhang D, Huang Y
Molecular medicine reports 2021 Mar;23(3)
Molecular medicine reports 2021 Mar;23(3)
Butyrate alleviates PTZ-induced mitochondrial dysfunction, oxidative stress and neuron apoptosis in mice via Keap1/Nrf2/HO-1 pathway.
Li D, Bai X, Jiang Y, Cheng Y
Brain research bulletin 2021 Mar;168:25-35
Brain research bulletin 2021 Mar;168:25-35
Ganglioside GD3 regulates dendritic growth in newborn neurons in adult mouse hippocampus via modulation of mitochondrial dynamics.
Tang FL, Wang J, Itokazu Y, Yu RK
Journal of neurochemistry 2021 Mar;156(6):819-833
Journal of neurochemistry 2021 Mar;156(6):819-833
AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation.
Bian X, Shi D, Xing K, Zhou H, Lu L, Yu D, Wu W
Clinical and translational medicine 2021 Mar;11(3):e352
Clinical and translational medicine 2021 Mar;11(3):e352
USP34 regulates tooth root morphogenesis by stabilizing NFIC.
Jiang S, Sheng R, Qi X, Wang J, Guo Y, Yuan Q
International journal of oral science 2021 Mar 9;13(1):7
International journal of oral science 2021 Mar 9;13(1):7
Endometrial cell-derived small extracellular vesicle miR-100-5p promotes functions of trophoblast during embryo implantation.
Tan Q, Shi S, Liang J, Cao D, Wang S, Wang Z
Molecular therapy. Nucleic acids 2021 Mar 5;23:217-231
Molecular therapy. Nucleic acids 2021 Mar 5;23:217-231
Hepatic HuR protects against the pathogenesis of non-alcoholic fatty liver disease by targeting PTEN.
Tian M, Wang J, Liu S, Li X, Li J, Yang J, Zhang C, Zhang W
Cell death & disease 2021 Mar 4;12(3):236
Cell death & disease 2021 Mar 4;12(3):236
HN1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by interacting with STMN1.
Pan Z, Fang Q, Li L, Zhang Y, Xu T, Liu Y, Zheng X, Tan Z, Huang P, Ge M
Cancer letters 2021 Mar 31;501:31-42
Cancer letters 2021 Mar 31;501:31-42
SIRT1 inhibitors mitigate radiation-induced GI syndrome by enhancing intestinal-stem-cell survival.
Fu G, Chen S, Liang L, Li X, Tang P, Rao X, Pan M, Xu X, Li Y, Yao Y, Zhou Y, Gao J, Mo S, Cai S, Peng J, Zhang Z, Clevers H, Gao J, Hua G
Cancer letters 2021 Mar 31;501:20-30
Cancer letters 2021 Mar 31;501:20-30
Selenite Inhibits Notch Signaling in Cells and Mice.
Powers M, Liu L, Deemer D, Chen S, Scholl A, Yoshinaga M, Liu Z
International journal of molecular sciences 2021 Mar 3;22(5)
International journal of molecular sciences 2021 Mar 3;22(5)
The effects of myeloablative or non-myeloablative total body irradiations on intestinal tract in mice.
Zhu S, Liang J, Zhu F, Zhang X, Xu M, Zhao K, Zeng L, Xu K
Bioscience reports 2021 Mar 26;41(3)
Bioscience reports 2021 Mar 26;41(3)
The antitumor role of a newly discovered α-d-glucan from Holotrichia diomphalia Bates as a selective blocker of aldolase A.
Wang J, Li Z, Yang X, Qiao Y, Feng C, Yu S, Jing H, Liu W, Ren L, Duan Q, Li XQ, Cao W
Carbohydrate polymers 2021 Mar 1;255:117532
Carbohydrate polymers 2021 Mar 1;255:117532
Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Exacerbates Podocyte Injury and the Progression of Diabetic Kidney Disease.
Qu H, Gong X, Liu X, Zhang R, Wang Y, Huang B, Zhang L, Zheng H, Zheng Y
Diabetes 2021 Jun;70(6):1372-1387
Diabetes 2021 Jun;70(6):1372-1387
Tanshinone IIA prevents LPS-induced inflammatory responses in mice via inactivation of succinate dehydrogenase in macrophages.
Liu QY, Zhuang Y, Song XR, Niu Q, Sun QS, Li XN, Li N, Liu BL, Huang F, Qiu ZX
Acta pharmacologica Sinica 2021 Jun;42(6):987-997
Acta pharmacologica Sinica 2021 Jun;42(6):987-997
Protective effects of total flavonoids from Qu Zhi Qiao (fruit of Citrus paradisi cv. Changshanhuyou) on OVA-induced allergic airway inflammation and remodeling through MAPKs and Smad2/3 signaling pathway.
Wang J, Li T, Cai H, Jin L, Li R, Shan L, Cai W, Jiang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111421
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111421
T(reg) deficiency-mediated T(H) 1 response causes human premature ovarian insufficiency through apoptosis and steroidogenesis dysfunction of granulosa cells.
Jiao X, Zhang X, Li N, Zhang D, Zhao S, Dang Y, Zanvit P, Jin W, Chen ZJ, Chen W, Qin Y
Clinical and translational medicine 2021 Jun;11(6):e448
Clinical and translational medicine 2021 Jun;11(6):e448
Immunoprecipitation Strategies to Isolate RIPK1/RIPK3 Complexes in Mouse Macrophages.
Siokas I, Zhang D, Poltorak A, Muendlein H, Degterev A
Current protocols 2021 Jun;1(6):e156
Current protocols 2021 Jun;1(6):e156
A human β-casein-derived peptide BCCY-1 modulates the innate immune response.
Cai J, Li X, Wang X, Jiang C, Shen D, Cui X, Xie K, Ji C, Cao Y
Food chemistry 2021 Jun 30;348:129111
Food chemistry 2021 Jun 30;348:129111
Dexmedetomidine post-conditioning attenuates cerebral ischemia following asphyxia cardiac arrest through down-regulation of apoptosis and neuroinflammation in rats.
Li G, LeiQian, Gu P, Fan D
BMC anesthesiology 2021 Jun 28;21(1):180
BMC anesthesiology 2021 Jun 28;21(1):180
DNA methylation mediated RSPO2 to promote follicular development in mammals.
Zhou X, He Y, Li N, Bai G, Pan X, Zhang Z, Zhang H, Li J, Yuan X
Cell death & disease 2021 Jun 26;12(7):653
Cell death & disease 2021 Jun 26;12(7):653
RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.
Wang H, Yang C, Li Y, Zhao S, Ma P, Mao B
Biochemical and biophysical research communications 2021 Jun 11;557:323-328
Biochemical and biophysical research communications 2021 Jun 11;557:323-328
Expression of Cntn1 is regulated by stress and associated with anxiety and depression phenotypes.
Li S, Cao W, Zhou S, Ma M, Zhang W, Li F, Li C
Brain, behavior, and immunity 2021 Jul;95:142-153
Brain, behavior, and immunity 2021 Jul;95:142-153
Engorgement of Rhipicephalus haemaphysaloides ticks blocked by silencing a protein inhibitor of apoptosis.
Tuerdi M, Hu S, Wang Y, Zhou Y, Cao J, Zhang H, Zhou J
Experimental & applied acarology 2021 Jul;84(3):623-636
Experimental & applied acarology 2021 Jul;84(3):623-636
Apoptotic caspases suppress Mycobacterium bovis-induced IFN-β production in murine macrophage.
Song Y, Dong Y, Liao Y, Liang Z, Yao J, Zhou X
The Journal of infection 2021 Jul;83(1):61-68
The Journal of infection 2021 Jul;83(1):61-68
Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin.
Hou K, Shen J, Yan J, Zhai C, Zhang J, Pan JA, Zhang Y, Jiang Y, Wang Y, Lin RZ, Cong H, Gao S, Zong WX
EBioMedicine 2021 Jul;69:103456
EBioMedicine 2021 Jul;69:103456
Reconsolidation of a post-ingestive nutrient memory requires mTOR in the central amygdala.
Yan Y, Zhang L, Zhu T, Deng S, Ma B, Lv H, Shan X, Cheng H, Jiang K, Zhang T, Meng B, Mei B, Li WG, Li F
Molecular psychiatry 2021 Jul;26(7):2820-2836
Molecular psychiatry 2021 Jul;26(7):2820-2836
Different roles of BAG3 in cardiac physiological hypertrophy and pathological remodeling.
Jia P, Wu N, Yang H, Guo Y, Guo X, Sun Y
Translational research : the journal of laboratory and clinical medicine 2021 Jul;233:47-61
Translational research : the journal of laboratory and clinical medicine 2021 Jul;233:47-61
Effects of cigarette smoke on the aggravation of ovalbumin-induced asthma and the expressions of TRPA1 and tight junctions in mice.
Sun YB, Liu M, Fan XS, Zhou LP, Li MW, Hu FY, Yue QF, Zhang YM
Molecular immunology 2021 Jul;135:62-72
Molecular immunology 2021 Jul;135:62-72
Enteric glial cells exert neuroprotection from hyperglycemia-induced damage via Akt/GSK3β pathway.
Luo P, He WX, Li C, Chang MJ
Neuroreport 2021 Jul 7;32(10):875-881
Neuroreport 2021 Jul 7;32(10):875-881
PKD2 deficiency suppresses amino acid biosynthesis in ADPKD by impairing the PERK-TBL2-eIF2ɑ-ATF4 pathway.
Zhou X, Xiong H, Lu Y, Geng M, Lu Y, Zhang L, Zhu X
Biochemical and biophysical research communications 2021 Jul 5;561:73-79
Biochemical and biophysical research communications 2021 Jul 5;561:73-79
Planar cell polarity induces local microtubule bundling for coordinated ciliary beating.
Nakayama S, Yano T, Namba T, Konishi S, Takagishi M, Herawati E, Nishida T, Imoto Y, Ishihara S, Takahashi M, Furuta K, Oiwa K, Tamura A, Tsukita S
The Journal of cell biology 2021 Jul 5;220(7)
The Journal of cell biology 2021 Jul 5;220(7)
Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress.
Cheng L, Chen T, Guo M, Liu P, Qiao X, Wei Y, She J, Li B, Xi W, Zhou J, Yuan Z, Wu Y, Liu J
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1689-1706
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1689-1706
HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity.
Luo W, Li J, Li Z, Lin T, Zhang L, Yang W, Mai Y, Liu R, Chen M, Dai C, Yang H, Lu J, Li H, Guan G, Huang M, Liu P, Li Z
Cell death & disease 2021 Jul 26;12(8):738
Cell death & disease 2021 Jul 26;12(8):738
Mitochondrial creatine kinase 1 in non-small cell lung cancer progression and hypoxia adaptation.
Li M, Liu H, Li J, Guo S, Lv Y
Respiratory research 2021 Jul 1;22(1):190
Respiratory research 2021 Jul 1;22(1):190
Actin-granule formation is an additional step in cardiac myofibroblast differentiation.
He L, Liu R, Yue H, Ren S, Zhu G, Guo Y, Qin C
Annals of translational medicine 2021 Jan;9(2):165
Annals of translational medicine 2021 Jan;9(2):165
Esomeprazole overcomes paclitaxel-resistance and enhances anticancer effects of paclitaxel by inducing autophagy in A549/Taxol cells.
Bai Z, Ding N, Ge J, Wang Y, Wang L, Wu N, Wei Q, Xu S, Liu X, Zhou G
Cell biology international 2021 Jan;45(1):177-187
Cell biology international 2021 Jan;45(1):177-187
Mefunidone ameliorates diabetic kidney disease in STZ and db/db mice.
Jiang Y, Xie F, Lv X, Wang S, Liao X, Yu Y, Dai Q, Zhang Y, Meng J, Hu G, Peng Z, Tao L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21198
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21198
Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer.
Zhang J, Chen Y, Chen X, Zhang W, Zhao L, Weng L, Tian H, Wu Z, Tan X, Ge X, Wang P, Fang L
Cell death and differentiation 2021 Jan;28(1):139-155
Cell death and differentiation 2021 Jan;28(1):139-155
The inhibition of colorectal cancer growth by the natural product macrocarpal I.
Qi L, Zhang Y, Zhang W, Wang Y, Han Y, Ding Y
Free radical biology & medicine 2021 Jan;162:383-391
Free radical biology & medicine 2021 Jan;162:383-391
Characteristics of inflammation process in monocrotaline-induced pulmonary arterial hypertension in rats.
Tang C, Luo Y, Li S, Huang B, Xu S, Li L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111081
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:111081
Neuroprotective effects of kukoamine A on 6-OHDA-induced Parkinson's model through apoptosis and iron accumulation inhibition.
Li X, Jiang XW, Chu HX, Zhao QC, Ding HW, Cai CH
Chinese herbal medicines 2021 Jan;13(1):105-115
Chinese herbal medicines 2021 Jan;13(1):105-115
Iron deficiency promotes aortic medial degeneration via destructing cytoskeleton of vascular smooth muscle cells.
Li B, Wang Z, Hong J, Che Y, Chen R, Hu Z, Hu X, Wu Q, Hu J, Zhang M
Clinical and translational medicine 2021 Jan;11(1):e276
Clinical and translational medicine 2021 Jan;11(1):e276
Skip participates in formation and lipid metabolism of beige adipose and might mediate the effects of SIRT1 activator BTM-0512 on beige remodeling.
Liao ZM, Li AN, Cai Y, Chen JJ, Xu Y, Sui LH, Wang JL, Jin P, Wang KS, Yang ZC
Biochemical and biophysical research communications 2021 Jan 22;537:109-117
Biochemical and biophysical research communications 2021 Jan 22;537:109-117
CSN6 promotes melanoma proliferation and metastasis by controlling the UBR5-mediated ubiquitination and degradation of CDK9.
Zhang Y, Hou J, Shi S, Du J, Liu Y, Huang P, Li Q, Liu L, Hu H, Ji Y, Guo L, Shi Y, Liu Y, Cui H
Cell death & disease 2021 Jan 22;12(1):118
Cell death & disease 2021 Jan 22;12(1):118
Exosomes derived from thymic stromal lymphopoietin-treated dendritic cells regulate T helper 17/regulatory T cell differentiation via miR-21/Smad7 axis.
Ji Q, Liu J, Dong Y, Wang L, Dong K, Setiz B, Szentmáry N, Qu B, Shi L
Experimental cell research 2021 Jan 1;398(1):112393
Experimental cell research 2021 Jan 1;398(1):112393
Changes in the expression of endothelial monocyte‑activating polypeptide II in the rat hippocampus following status epilepticus.
Li C, Ma W, Zhao Y, Wang H
International journal of molecular medicine 2021 Feb;47(2):699-707
International journal of molecular medicine 2021 Feb;47(2):699-707
METTL3-Mediated m(6) A mRNA Methylation Modulates Tooth Root Formation by Affecting NFIC Translation.
Sheng R, Wang Y, Wu Y, Wang J, Zhang S, Li Q, Zhang D, Qi X, Xiao Q, Jiang S, Yuan Q
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2021 Feb;36(2):412-423
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2021 Feb;36(2):412-423
Chlorpromazine, an antipsychotic agent, induces G2/M phase arrest and apoptosis via regulation of the PI3K/AKT/mTOR-mediated autophagy pathways in human oral cancer.
Jhou AJ, Chang HC, Hung CC, Lin HC, Lee YC, Liu WT, Han KF, Lai YW, Lin MY, Lee CH
Biochemical pharmacology 2021 Feb;184:114403
Biochemical pharmacology 2021 Feb;184:114403
Targeting ROCK1/2 blocks cell division and induces mitotic catastrophe in hepatocellular carcinoma.
Wu H, Chen Y, Li B, Li C, Guo J, You J, Hu X, Kuang D, Qi S, Liu P, Li L, Xu C
Biochemical pharmacology 2021 Feb;184:114353
Biochemical pharmacology 2021 Feb;184:114353
Knockdown of ASH1L methyltransferase induced apoptosis inhibiting proliferation and H3K36 methylation in bovine cumulus cells.
Cui LX, Tian YQ, Hao HS, Zou HY, Pang YW, Zhao SJ, Zhao XM, Zhu HB, Du WH
Theriogenology 2021 Feb;161:65-73
Theriogenology 2021 Feb;161:65-73
Vascular endothelial growth factor alleviates mitochondrial dysfunction and suppression of mitochondrial biogenesis in models of Alzheimer's disease.
Liu X, Chu B, Jin S, Li M, Xu Y, Yang H, Feng Z, Bi J, Wang P
The International journal of neuroscience 2021 Feb;131(2):154-162
The International journal of neuroscience 2021 Feb;131(2):154-162
Integrated analysis of microRNA and mRNA expression profiling identifies BAIAP3 as a novel target of dysregulated hsa-miR-1972 in age-related white matter lesions.
Huang WQ, Lin Q, Chen S, Sun L, Chen Q, Yi K, Li Z, Ma Q, Tzeng CM
Aging 2021 Feb 9;13(3):4674-4695
Aging 2021 Feb 9;13(3):4674-4695
Central role of TRAP1 in the ameliorative effect of oleanolic acid on the mitochondrial-mediated and endoplasmic reticulum stress-excitated apoptosis induced by ochratoxin A.
Zhang Q, Chen W, Zhang B, Li C, Zhang X, Wang Q, Wang Y, Zhou Q, Li X, Shen XL
Toxicology 2021 Feb 28;450:152681
Toxicology 2021 Feb 28;450:152681
Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing.
Li J, Liu F, Lv Y, Sun K, Zhao Y, Reilly J, Zhang Y, Tu J, Yu S, Liu X, Qin Y, Huang Y, Gao P, Jia D, Chen X, Han Y, Shu X, Luo D, Tang Z, Liu M
Nucleic acids research 2021 Feb 26;49(4):2027-2043
Nucleic acids research 2021 Feb 26;49(4):2027-2043
High glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy.
Wu QR, Zheng DL, Liu PM, Yang H, Li LA, Kuang SJ, Lai YY, Rao F, Xue YM, Lin JJ, Liu SX, Chen CB, Deng CY
Cell death & disease 2021 Feb 26;12(2):216
Cell death & disease 2021 Feb 26;12(2):216
Aberrantly high activation of a FoxM1-STMN1 axis contributes to progression and tumorigenesis in FoxM1-driven cancers.
Liu J, Li J, Wang K, Liu H, Sun J, Zhao X, Yu Y, Qiao Y, Wu Y, Zhang X, Zhang R, Yang A
Signal transduction and targeted therapy 2021 Feb 1;6(1):42
Signal transduction and targeted therapy 2021 Feb 1;6(1):42
Semaphorin 3A promotes the osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells in inflammatory environments by suppressing the Wnt/β-catenin signaling pathway.
Sun Z, Yan K, Liu S, Yu X, Xu J, Liu J, Li S
Journal of molecular histology 2021 Dec;52(6):1245-1255
Journal of molecular histology 2021 Dec;52(6):1245-1255
Histone Deacetylase Inhibitor SAHA Induces Expression of Fatty Acid-Binding Protein 4 and Inhibits Replication of Human Cytomegalovirus.
Liu Z, Xuan B, Tang S, Qian Z
Virologica Sinica 2021 Dec;36(6):1352-1362
Virologica Sinica 2021 Dec;36(6):1352-1362
Small molecule targeting topoisomerase 3β for cancer therapy.
Zhang X, Wang L, Zhang Q, Lyu S, Zhu D, Shen M, Ke X, Qu Y
Pharmacological research 2021 Dec;174:105927
Pharmacological research 2021 Dec;174:105927
Keratin 19 maintains E-cadherin localization at the cell surface and stabilizes cell-cell adhesion of MCF7 cells.
Alsharif S, Sharma P, Bursch K, Milliken R, Lam V, Fallatah A, Phan T, Collins M, Dohlman P, Tiufekchiev S, Nehmetallah G, Raub CB, Chung BM
Cell adhesion & migration 2021 Dec;15(1):1-17
Cell adhesion & migration 2021 Dec;15(1):1-17
Effects and mechanisms of probucol on aging-related hippocampus-dependent cognitive impairment.
Xie Y, Song A, Zhu Y, Jiang A, Peng W, Zhang C, Meng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112266
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112266
Single-cell transcriptome atlas of human mesenchymal stem cells exploring cellular heterogeneity.
Wang Z, Chai C, Wang R, Feng Y, Huang L, Zhang Y, Xiao X, Yang S, Zhang Y, Zhang X
Clinical and translational medicine 2021 Dec;11(12):e650
Clinical and translational medicine 2021 Dec;11(12):e650
MiR-155-5p suppresses SOX1 to promote proliferation of cholangiocarcinoma via RAF/MEK/ERK pathway.
Wang D, Xiong F, Wu G, Liu W, Wang B, Chen Y
Cancer cell international 2021 Dec 7;21(1):656
Cancer cell international 2021 Dec 7;21(1):656
Initiation of oogenesis and meiosis in the fetal ovary depends on Dennd1a-mediated production of Wnt5a and retinoic acid from the somatic niches.
Shi J, Niu Q, Gao Q, Fu J, Ma J
Frontiers in bioscience (Landmark edition) 2021 Dec 30;26(12):1513-1524
Frontiers in bioscience (Landmark edition) 2021 Dec 30;26(12):1513-1524
The RNA binding protein QKI5 suppresses ovarian cancer via downregulating transcriptional coactivator TAZ.
Liu T, Yang Y, Xie Z, Luo Q, Yang D, Liu X, Zhao H, Wei Q, Liu Y, Li L, Wang Y, Wang F, Yu J, Xu J, Yu J, Yi P
Molecular therapy. Nucleic acids 2021 Dec 3;26:388-400
Molecular therapy. Nucleic acids 2021 Dec 3;26:388-400
A circuit of COCH neurons encodes social-stress-induced anxiety via MTF1 activation of Cacna1h.
Jing W, Zhang T, Liu J, Huang X, Yu Q, Yu H, Zhang Q, Li H, Deng M, Zhu LQ, Du H, Lu Y
Cell reports 2021 Dec 28;37(13):110177
Cell reports 2021 Dec 28;37(13):110177
Loss-of-function missense variant of AKAP4 induced male infertility through reduced interaction with QRICH2 during sperm flagella development.
Zhang G, Li D, Tu C, Meng L, Tan Y, Ji Z, Cheng J, Lu G, Lin G, Zhang H, Sun J, Wang M, Du J, Xu W
Human molecular genetics 2021 Dec 27;31(2):219-231
Human molecular genetics 2021 Dec 27;31(2):219-231
miR-378d suppresses malignant phenotype of ESCC cells through AKT signaling.
Peng J, Shi S, Yu J, Liu J, Wei H, Song H, Wang S, Li Z, He S, Li L, Zhang H, Yan Z, Zhao R, Liu Y, Liu Y, Li J, Zhang R, Wang W
Cancer cell international 2021 Dec 22;21(1):702
Cancer cell international 2021 Dec 22;21(1):702
Drp1 SUMO/deSUMOylation by Senp5 isoforms influences ER tubulation and mitochondrial dynamics to regulate brain development.
Yamada S, Sato A, Ishihara N, Akiyama H, Sakakibara SI
iScience 2021 Dec 17;24(12):103484
iScience 2021 Dec 17;24(12):103484
Copper depletion modulates mitochondrial oxidative phosphorylation to impair triple negative breast cancer metastasis.
Ramchandani D, Berisa M, Tavarez DA, Li Z, Miele M, Bai Y, Lee SB, Ban Y, Dephoure N, Hendrickson RC, Cloonan SM, Gao D, Cross JR, Vahdat LT, Mittal V
Nature communications 2021 Dec 15;12(1):7311
Nature communications 2021 Dec 15;12(1):7311
Prototheca spp. induce an inflammatory response via mtROS-mediated activation of NF-κB and NLRP3 inflammasome pathways in bovine mammary epithelial cell cultures.
Zhao W, He F, Barkema HW, Xu S, Gao J, Liu G, Deng Z, Shahid M, Shi Y, Kastelic JP, Han B
Veterinary research 2021 Dec 11;52(1):144
Veterinary research 2021 Dec 11;52(1):144
GP73 is a TBC-domain Rab GTPase-activating protein contributing to the pathogenesis of non-alcoholic fatty liver disease without obesity.
Peng Y, Zeng Q, Wan L, Ma E, Li H, Yang X, Zhang Y, Huang L, Lin H, Feng J, Xu Y, Li J, Liu M, Liu J, Lin C, Sun Z, Cheng G, Zhang X, Liu J, Li D, Wei M, Mo Y, Mu X, Deng X, Zhang D, Dong S, Huang H, Fang Y, Gao Q, Yang X, Wu F, Zhong H, Wei C
Nature communications 2021 Dec 1;12(1):7004
Nature communications 2021 Dec 1;12(1):7004
ZNRF2 attenuates focal cerebral ischemia/reperfusion injury in rats by inhibiting mTORC1-mediated autophagy.
Gu C, Yang J, Luo Y, Ran D, Tan X, Xiang P, Fei H, Lu Y, Guo W, Tu Y, Liu X, Wang H
Experimental neurology 2021 Aug;342:113759
Experimental neurology 2021 Aug;342:113759
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target.
Xia B, Shen X, He Y, Pan X, Liu FL, Wang Y, Yang F, Fang S, Wu Y, Duan Z, Zuo X, Xie Z, Jiang X, Xu L, Chi H, Li S, Meng Q, Zhou H, Zhou Y, Cheng X, Xin X, Jin L, Zhang HL, Yu DD, Li MH, Feng XL, Chen J, Jiang H, Xiao G, Zheng YT, Zhang LK, Shen J, Li J, Gao Z
Cell research 2021 Aug;31(8):847-860
Cell research 2021 Aug;31(8):847-860
Aagab acts as a novel regulator of NEDD4-1-mediated Pten nuclear translocation to promote neurological recovery following hypoxic-ischemic brain damage.
Dai C, Wu B, Chen Y, Li X, Bai Y, Du Y, Pang Y, Wang YT, Dong Z
Cell death and differentiation 2021 Aug;28(8):2367-2384
Cell death and differentiation 2021 Aug;28(8):2367-2384
K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle.
Yu Y, Zheng Q, Erramilli SK, Pan M, Park S, Xie Y, Li J, Fei J, Kossiakoff AA, Liu L, Zhao M
Nature chemical biology 2021 Aug;17(8):896-905
Nature chemical biology 2021 Aug;17(8):896-905
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.
Xianjun F, Xirui X, Jie T, Huiwen M, Shaojun Z, Qiaoyun L, Yunxin L, Xuqun S
Journal of pharmacological sciences 2021 Aug;146(4):249-258
Journal of pharmacological sciences 2021 Aug;146(4):249-258
AHR mediates the aflatoxin B1 toxicity associated with hepatocellular carcinoma.
Zhu Q, Ma Y, Liang J, Wei Z, Li M, Zhang Y, Liu M, He H, Qu C, Cai J, Wang X, Zeng Y, Jiao Y
Signal transduction and targeted therapy 2021 Aug 9;6(1):299
Signal transduction and targeted therapy 2021 Aug 9;6(1):299
Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration.
Li J, Wang S, Wang N, Zheng Y, Yang B, Wang X, Zhang J, Pan B, Wang Z
Cell communication and signaling : CCS 2021 Aug 30;19(1):89
Cell communication and signaling : CCS 2021 Aug 30;19(1):89
The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects.
Li J, Yan Z, Li H, Shi Q, Ahire V, Zhang S, Nimishetti N, Yang D, Allen TD, Zhang J
Journal of natural products 2021 Aug 27;84(8):2312-2320
Journal of natural products 2021 Aug 27;84(8):2312-2320
WDR62 regulates spindle dynamics as an adaptor protein between TPX2/Aurora A and katanin.
Huang J, Liang Z, Guan C, Hua S, Jiang K
The Journal of cell biology 2021 Aug 2;220(8)
The Journal of cell biology 2021 Aug 2;220(8)
Haploinsufficiency of the TDP43 ubiquitin E3 ligase RNF220 leads to ALS-like motor neuron defects in the mouse.
Ma P, Li Y, Wang H, Mao B
Journal of molecular cell biology 2021 Aug 18;13(5):374-382
Journal of molecular cell biology 2021 Aug 18;13(5):374-382
CBL aggravates Ang II-induced cardiac hypertrophy via the VHL/HIF-1α pathway.
Yang Y, Zou P, He L, Shao J, Tang Y, Li J
Experimental cell research 2021 Aug 15;405(2):112730
Experimental cell research 2021 Aug 15;405(2):112730
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Du Y, Wang J, Xiong J, Fang N, Ji WK
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Adenosine A3 receptor activated in H(2)O(2) oxidative stress of primary open-angle glaucoma.
Zhou Z, Gao Z, Yan W, Zhang Y, Huang J, Xiong K
Annals of translational medicine 2021 Apr;9(7):526
Annals of translational medicine 2021 Apr;9(7):526
Triterpene saponins from Guo-gang-long attenuate collagen-induced arthritis via regulating A20 and inhibiting MAPK pathway.
Xiong H, Luo M, Ju Y, Zhao Z, Zhang M, Xu R, Ren Y, Yang G, Mei Z
Journal of ethnopharmacology 2021 Apr 6;269:113707
Journal of ethnopharmacology 2021 Apr 6;269:113707
Human splenic TER cells: A relevant prognostic factor acting via the artemin-GFRα3-ERK pathway in pancreatic ductal adenocarcinoma.
Li TJ, Li H, Zhang WH, Xu SS, Jiang W, Li S, Gao HL, Han X, Xu HX, Wu CT, Wang WQ, Yu XJ, Liu L
International journal of cancer 2021 Apr 1;148(7):1756-1767
International journal of cancer 2021 Apr 1;148(7):1756-1767
Dnajb8, a target gene of SOX30, is dispensable for male fertility in mice.
Wang F, Kong S, Hu X, Li X, Xu B, Yue Q, Fu K, Ye L, Bai S
PeerJ 2020;8:e10582
PeerJ 2020;8:e10582
ASPH Regulates Osteogenic Differentiation and Cellular Senescence of BMSCs.
Peng H, Guo Q, Xiao Y, Su T, Jiang TJ, Guo LJ, Wang M
Frontiers in cell and developmental biology 2020;8:872
Frontiers in cell and developmental biology 2020;8:872
An MRTF-A-Sp1-PDE5 Axis Mediates Angiotensin-II-Induced Cardiomyocyte Hypertrophy.
Wu T, Wang H, Xin X, Yang J, Hou Y, Fang M, Lu X, Xu Y
Frontiers in cell and developmental biology 2020;8:839
Frontiers in cell and developmental biology 2020;8:839
Modulation of Increased mGluR1 Signaling by RGS8 Protects Purkinje Cells From Dendritic Reduction and Could Be a Common Mechanism in Diverse Forms of Spinocerebellar Ataxia.
Wu QW, Kapfhammer JP
Frontiers in cell and developmental biology 2020;8:569889
Frontiers in cell and developmental biology 2020;8:569889
PCDH7 Inhibits the Formation of Homotypic Cell-in-Cell Structure.
Wang C, Chen A, Ruan B, Niu Z, Su Y, Qin H, Zheng Y, Zhang B, Gao L, Chen Z, Huang H, Wang X, Sun Q
Frontiers in cell and developmental biology 2020;8:329
Frontiers in cell and developmental biology 2020;8:329
RGS12 is required for the maintenance of mitochondrial function during skeletal development.
Yuan G, Yang S, Liu M, Yang S
Cell discovery 2020;6:59
Cell discovery 2020;6:59
Glutamine protects intestine against ischemia-reperfusion injury by alleviating endoplasmic reticulum stress induced apoptosis in rats.
Xu H, Liu G, Gu H, Wang J, Li Y
Acta cirurgica brasileira 2020;35(1):e202000104
Acta cirurgica brasileira 2020;35(1):e202000104
Ambroxol Improves Neuronal Survival and Reduces White Matter Damage through Suppressing Endoplasmic Reticulum Stress in Microglia after Intracerebral Hemorrhage.
Jiang X, Zhang J, Kou B, Zhang C, Zhong J, Fang X, Huang X, Zhang X, Xie F, Hu Q, Ge H, Yu A
BioMed research international 2020;2020:8131286
BioMed research international 2020;2020:8131286
Mogroside V Protects against Hepatic Steatosis in Mice on a High-Fat Diet and LO2 Cells Treated with Free Fatty Acids via AMPK Activation.
Li L, Zheng W, Wang C, Qi J, Li H
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7826874
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7826874
MicroRNA-384 Inhibits the Progression of Papillary Thyroid Cancer by Targeting PRKACB.
Wang Y, Wang B, Zhou H, Zhang X, Qian X, Cui J
BioMed research international 2020;2020:4983420
BioMed research international 2020;2020:4983420
Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis.
Du J, Ren W, Zhang Q, Fu N, Han F, Cui P, Li W, Kong L, Zhao S, Wang R, Zhang Y, Yang L, Kong L, Nan Y
BioMed research international 2020;2020:4910601
BioMed research international 2020;2020:4910601
Wnt5a/CaMKII/ERK/CCL2 axis is required for tumor-associated macrophages to promote colorectal cancer progression.
Liu Q, Song J, Pan Y, Shi D, Yang C, Wang S, Xiong B
International journal of biological sciences 2020;16(6):1023-1034
International journal of biological sciences 2020;16(6):1023-1034
MicroRNA-148a regulates low-density lipoprotein metabolism by repressing the (pro)renin receptor.
Wang N, He L, Lin H, Tan L, Sun Y, Zhang X, Danser AHJ, Lu HS, He Y, Lu X
PloS one 2020;15(5):e0225356
PloS one 2020;15(5):e0225356
DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway.
Luo J, Luo X, Liu X, Fang Z, Xu J, Li L
OncoTargets and therapy 2020;13:1321-1330
OncoTargets and therapy 2020;13:1321-1330
Kaempferol attenuated cisplatin-induced cardiac injury via inhibiting STING/NF-κB-mediated inflammation.
Qi Y, Ying Y, Zou J, Fang Q, Yuan X, Cao Y, Cai Y, Fu S
American journal of translational research 2020;12(12):8007-8018
American journal of translational research 2020;12(12):8007-8018
EphA5 Silencing Increases the Radiosensitivity of ESCC Cells Through ATM-Dependent Pathway.
Zhang R, Han D, Li L, Luo W, Liu J, Qian L
Cancer management and research 2020;12:9539-9549
Cancer management and research 2020;12:9539-9549
Hypoxia-induced MFAP5 Promotes Tumor Migration and Invasion via AKT Pathway in Head and Neck Squamous Cell Carcinoma.
Xu Q, Chang H, Tian X, Lou C, Ma H, Yang X
Journal of Cancer 2020;11(6):1596-1605
Journal of Cancer 2020;11(6):1596-1605
Phosphoribosyl pyrophosphate synthetases 2 knockdown inhibits prostate cancer progression by suppressing cell cycle and inducing cell apoptosis.
Qiao H, Tan X, Lv DJ, Xing RW, Shu FP, Zhong CF, Li C, Zou YG, Mao XM
Journal of Cancer 2020;11(5):1027-1037
Journal of Cancer 2020;11(5):1027-1037
Overexpression of KIAA0101 Promotes the Progression of Non-small Cell Lung Cancer.
Cao H, Zheng J, Yao Y, Yang Q, Yan R, Sun W, Ruan K, Zhou J, Zhou J
Journal of Cancer 2020;11(22):6663-6674
Journal of Cancer 2020;11(22):6663-6674
Inward Tension of Talin and Integrin-related Osmotic Pressure are involved Synergetically in the Invasion and Metastasis of Non-small Cell Lung Cancer.
Song Y, Li C, Fu Y, Xie Q, Guo J, Li G, Wu H
Journal of Cancer 2020;11(17):5032-5041
Journal of Cancer 2020;11(17):5032-5041
High-Intensity Interval Training Restores Glycolipid Metabolism and Mitochondrial Function in Skeletal Muscle of Mice With Type 2 Diabetes.
Zheng L, Rao Z, Guo Y, Chen P, Xiao W
Frontiers in endocrinology 2020;11:561
Frontiers in endocrinology 2020;11:561
Coxsackievirus A6 Induces Necroptosis for Viral Production.
Zhang S, Yu X, Meng X, Huo W, Su Y, Liu J, Liu Y, Zhang J, Wang S, Yu J
Frontiers in microbiology 2020;11:42
Frontiers in microbiology 2020;11:42
Establishment of cell lines with porcine spermatogonial stem cell properties.
Zheng Y, Feng T, Zhang P, Lei P, Li F, Zeng W
Journal of animal science and biotechnology 2020;11:33
Journal of animal science and biotechnology 2020;11:33
Poricoic acid A as a modulator of TPH-1 expression inhibits renal fibrosis via modulating protein stability of β-catenin and β-catenin-mediated transcription.
Chen DQ, Wu XQ, Chen L, Hu HH, Wang YN, Zhao YY
Therapeutic advances in chronic disease 2020;11:2040622320962648
Therapeutic advances in chronic disease 2020;11:2040622320962648
SYTL4 downregulates microtubule stability and confers paclitaxel resistance in triple-negative breast cancer.
Liu XY, Jiang W, Ma D, Ge LP, Yang YS, Gou ZC, Xu XE, Shao ZM, Jiang YZ
Theranostics 2020;10(24):10940-10956
Theranostics 2020;10(24):10940-10956
Protein acetylation derepresses Serotonin Synthesis to potentiate Pancreatic Beta-Cell Function through HDAC1-PKA-Tph1 signaling.
Zhang Y, Wang S, Zhang L, Zhou F, Zhu K, Zhu Q, Liu Q, Liu Y, Jiang L, Ning G, Bi Y, Zhou L, Wang X
Theranostics 2020;10(16):7351-7368
Theranostics 2020;10(16):7351-7368
Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
Zou G, Zhang X, Wang L, Li X, Xie T, Zhao J, Yan J, Wang L, Ye H, Jiao S, Xiang R, Shi Y
Theranostics 2020;10(15):6839-6853
Theranostics 2020;10(15):6839-6853
A Prognostic Prediction Model Developed Based on Four CpG Sites and Weighted Correlation Network Analysis Identified DNAJB1 as a Novel Biomarker for Pancreatic Cancer.
Kong L, Liu P, Fei X, Wu T, Wang Z, Zhang B, Li J, Tan X
Frontiers in oncology 2020;10:1716
Frontiers in oncology 2020;10:1716
SYPL1 Inhibits Apoptosis in Pancreatic Ductal Adenocarcinoma via Suppression of ROS-Induced ERK Activation.
Song Y, Sun X, Duan F, He C, Wu J, Huang X, Xing K, Sun S, Wang R, Xie F, Mao Y, Wang J, Li S
Frontiers in oncology 2020;10:1482
Frontiers in oncology 2020;10:1482
Caspase-3 inhibitor inhibits enterovirus D68 production.
Huo W, Yu J, Liu C, Wu T, Wang Y, Meng X, Song F, Zhang S, Su Y, Liu Y, Liu J, Yu X, Hua S
Journal of microbiology (Seoul, Korea) 2020 Sep;58(9):812-820
Journal of microbiology (Seoul, Korea) 2020 Sep;58(9):812-820
The chromatin remodeler Brg1 is required for formation and maintenance of hematopoietic stem cells.
Tu J, Liu X, Jia H, Reilly J, Yu S, Cai C, Liu F, Lv Y, Huang Y, Lu Z, Han S, Jiang T, Shu X, Wu X, Tang Z, Lu Q, Liu M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):11997-12008
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Sep;34(9):11997-12008
Therapeutic efficacy of antisense oligonucleotides in mouse models of CLN3 Batten disease.
Centa JL, Jodelka FM, Hinrich AJ, Johnson TB, Ochaba J, Jackson M, Duelli DM, Weimer JM, Rigo F, Hastings ML
Nature medicine 2020 Sep;26(9):1444-1451
Nature medicine 2020 Sep;26(9):1444-1451
Dependence of PINK1 accumulation on mitochondrial redox system.
Gao F, Zhang Y, Hou X, Tao Z, Ren H, Wang G
Aging cell 2020 Sep;19(9):e13211
Aging cell 2020 Sep;19(9):e13211
Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway.
Yang Y, Wang Q, Song D, Zen R, Zhang L, Wang Y, Yang H, Zhang D, Jia J, Zhang J, Wang J
Journal of experimental & clinical cancer research : CR 2020 Sep 22;39(1):197
Journal of experimental & clinical cancer research : CR 2020 Sep 22;39(1):197
Comprehensive lipidomics in apoM(-/-) mice reveals an overall state of metabolic distress and attenuated hepatic lipid secretion into the circulation.
Shi Y, Lam SM, Liu H, Luo G, Zhang J, Yao S, Li J, Zheng L, Xu N, Zhang X, Shui G
Journal of genetics and genomics = Yi chuan xue bao 2020 Sep 20;47(9):523-534
Journal of genetics and genomics = Yi chuan xue bao 2020 Sep 20;47(9):523-534
Metformin improves boar sperm quality via 5'-AMP-activated protein kinase-mediated energy metabolism in vitro.
Li RN, Zhu ZD, Zheng Y, Lv YH, Tian XE, Wu D, Wang YJ, Zeng WX
Zoological research 2020 Sep 18;41(5):527-538
Zoological research 2020 Sep 18;41(5):527-538
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
Xu J, Zhang Y, You S, Guo Y, Chen S, Chang Y, Zhang N, Sun Y
Life sciences 2020 Sep 15;257:118053
Life sciences 2020 Sep 15;257:118053
Consumption of a Blueberry-Enriched Diet by Women for 6 Weeks Alters Determinants of Human Muscle Progenitor Cell Function.
Blum JE, Gheller BJ, Hwang S, Bender E, Gheller M, Thalacker-Mercer AE
The Journal of nutrition 2020 Sep 1;150(9):2412-2418
The Journal of nutrition 2020 Sep 1;150(9):2412-2418
Proline Protects Boar Sperm against Oxidative Stress through Proline Dehydrogenase-Mediated Metabolism and the Amine Structure of Pyrrolidine.
Feng C, Zhu Z, Bai W, Li R, Zheng Y, Tian X, Wu D, Lu H, Wang Y, Zeng W
Animals : an open access journal from MDPI 2020 Sep 1;10(9)
Animals : an open access journal from MDPI 2020 Sep 1;10(9)
NQO1-selective activated prodrugs of combretastatin A-4: Synthesis and biological evaluation.
Zhang C, Qu Y, Ma X, Li M, Li S, Li Y, Wu L
Bioorganic chemistry 2020 Oct;103:104200
Bioorganic chemistry 2020 Oct;103:104200
SARS-CoV-2 triggers inflammatory responses and cell death through caspase-8 activation.
Li S, Zhang Y, Guan Z, Li H, Ye M, Chen X, Shen J, Zhou Y, Shi ZL, Zhou P, Peng K
Signal transduction and targeted therapy 2020 Oct 9;5(1):235
Signal transduction and targeted therapy 2020 Oct 9;5(1):235
Lycorine hydrochloride inhibits cell proliferation and induces apoptosis through promoting FBXW7-MCL1 axis in gastric cancer.
Li C, Deng C, Pan G, Wang X, Zhang K, Dong Z, Zhao G, Tan M, Hu X, Shi S, Du J, Ji H, Wang X, Yang L, Cui H
Journal of experimental & clinical cancer research : CR 2020 Oct 30;39(1):230
Journal of experimental & clinical cancer research : CR 2020 Oct 30;39(1):230
Broad-complex transcription factor mediates opposing hormonal regulation of two phylogenetically distant arginine kinase genes in Tribolium castaneum.
Zhang N, Jiang H, Meng X, Qian K, Liu Y, Song Q, Stanley D, Wu J, Park Y, Wang J
Communications biology 2020 Oct 30;3(1):631
Communications biology 2020 Oct 30;3(1):631
JARID1B promotes colorectal cancer proliferation and Wnt/β-catenin signaling via decreasing CDX2 level.
Huang D, Xiao F, Hao H, Hua F, Luo Z, Huang Z, Li Q, Chen S, Cheng X, Zhang X, Fang W, Hu X, Liu F
Cell communication and signaling : CCS 2020 Oct 27;18(1):169
Cell communication and signaling : CCS 2020 Oct 27;18(1):169
HOXA13 promotes colon cancer progression through β-catenin-dependent WNT pathway.
Gu Y, Gu J, Shen K, Zhou H, Hao J, Li F, Yu H, Chen Y, Li J, Li Y, Liang H, Dong Y
Experimental cell research 2020 Oct 15;395(2):112238
Experimental cell research 2020 Oct 15;395(2):112238
Platycodon grandifloras polysaccharides inhibit mitophagy injury induced by Cr (VI) in DF-1 cells.
Hao J, Song Y, Tian B, Qi C, Li L, Wang L, Xing Y, Zhao X, Liu J
Ecotoxicology and environmental safety 2020 Oct 1;202:110901
Ecotoxicology and environmental safety 2020 Oct 1;202:110901
Sulforaphane-cysteine inhibited migration and invasion via enhancing mitophagosome fusion to lysosome in human glioblastoma cells.
Zhou Y, Wang Y, Wu S, Yan Y, Hu Y, Zheng Z, Li J, Wu W
Cell death & disease 2020 Oct 1;11(9):819
Cell death & disease 2020 Oct 1;11(9):819
Anti-inflammatory and analgesic activities of indigo through regulating the IKKβ/IκB/NF-κB pathway in mice.
Liu N, Zhang GX, Niu YT, Wang Q, Zheng J, Yang JM, Sun T, Niu JG, Yu JQ
Food & function 2020 Oct 1;11(10):8537-8546
Food & function 2020 Oct 1;11(10):8537-8546
Atractyloside targets cancer-associated fibroblasts and inhibits the metastasis of colon cancer.
Qi L, Song F, Han Y, Zhang Y, Ding Y
Annals of translational medicine 2020 Nov;8(21):1443
Annals of translational medicine 2020 Nov;8(21):1443
Arginase 1 is involved in lacrimal hyposecretion in male NOD mice, a model of Sjögren's syndrome, regardless of dacryoadenitis status.
Ohno Y, Satoh K, Shitara A, Into T, Kashimata M
The Journal of physiology 2020 Nov;598(21):4907-4925
The Journal of physiology 2020 Nov;598(21):4907-4925
Elevated miR-124-3p in the aging colon disrupts mucus barrier and increases susceptibility to colitis by targeting T-synthase.
Huang L, Sun TY, Hu LJ, Hu SL, Sun HM, Zhao FQ, Wu B, Yang S, Ji FQ, Zhou DS
Aging cell 2020 Nov;19(11):e13252
Aging cell 2020 Nov;19(11):e13252
Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity.
Mabbitt PD, Loreto A, Déry MA, Fletcher AJ, Stanley M, Pao KC, Wood NT, Coleman MP, Virdee S
Nature chemical biology 2020 Nov;16(11):1227-1236
Nature chemical biology 2020 Nov;16(11):1227-1236
Melatonin Rescues the Ti Particle-Impaired Osteogenic Potential of Bone Marrow Mesenchymal Stem Cells via the SIRT1/SOD2 Signaling Pathway.
Zhang Y, Zhu X, Wang G, Chen L, Yang H, He F, Lin J
Calcified tissue international 2020 Nov;107(5):474-488
Calcified tissue international 2020 Nov;107(5):474-488
Oroxylin A alleviates immunoparalysis of CLP mice by degrading CHOP through interacting with FBXO15.
Zhang Z, Wang Y, Shan Y, Zhou R, Yin W
Scientific reports 2020 Nov 6;10(1):19272
Scientific reports 2020 Nov 6;10(1):19272
Acetylharpagide Protects Mice from Staphylococcus Aureus-Induced Acute Lung Injury by Inhibiting NF-κB Signaling Pathway.
Zhang Z, Wang Y, Shan Y, Yin W
Molecules (Basel, Switzerland) 2020 Nov 25;25(23)
Molecules (Basel, Switzerland) 2020 Nov 25;25(23)
Water treadmill training attenuates blood-spinal cord barrier disruption in rats by promoting angiogenesis and inhibiting matrix metalloproteinase-2/9 expression following spinal cord injury.
Ying X, Xie Q, Li S, Yu X, Zhou K, Yue J, Chen X, Tu W, Yang G, Jiang S
Fluids and barriers of the CNS 2020 Nov 25;17(1):70
Fluids and barriers of the CNS 2020 Nov 25;17(1):70
Cell Signaling Coordinates Global PRC2 Recruitment and Developmental Gene Expression in Murine Embryonic Stem Cells.
Aljazi MB, Gao Y, Wu Y, Mias GI, He J
iScience 2020 Nov 20;23(11):101646
iScience 2020 Nov 20;23(11):101646
The RCAN1.4-calcineurin/NFAT signaling pathway is essential for hypoxic adaption of intervertebral discs.
Huang B, He Y, Li S, Wei X, Liu J, Shan Z, Huang Y, Chen J, Zhao F
Experimental & molecular medicine 2020 May;52(5):865-875
Experimental & molecular medicine 2020 May;52(5):865-875
DNA methylation‑regulated miR‑155‑5p depresses sensitivity of esophageal carcinoma cells to radiation and multiple chemotherapeutic drugs via suppression of MAP3K10.
Luo W, Zhang H, Liang X, Xia R, Deng H, Yi Q, Lv L, Qian L
Oncology reports 2020 May;43(5):1692-1704
Oncology reports 2020 May;43(5):1692-1704
Cognitive improvement and synaptic deficit attenuation by a multifunctional carbazole-based cyanine in AD mice model through regulation of Ca(2+)/CaMKII/CREB signaling pathway.
Chen C, Xu D, Zhang ZH, Jia SZ, Cao XC, Chen YB, Song GL, Wong MS, Li HW
Experimental neurology 2020 May;327:113210
Experimental neurology 2020 May;327:113210
MKL1 mediates TGF-β-induced CTGF transcription to promote renal fibrosis.
Mao L, Liu L, Zhang T, Wu X, Zhang T, Xu Y
Journal of cellular physiology 2020 May;235(5):4790-4803
Journal of cellular physiology 2020 May;235(5):4790-4803
Modulation of SIRT1-mediated signaling cascades in the liver contributes to the amelioration of nonalcoholic steatohepatitis in high fat fed middle-aged LDL receptor knockout mice by dihydromyricetin.
Zeng Y, Hua YQ, Wang W, Zhang H, Xu XL
Biochemical pharmacology 2020 May;175:113927
Biochemical pharmacology 2020 May;175:113927
The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double-strand break repair.
Huang T, Yuan S, Gao L, Li M, Yu X, Zhan J, Yin Y, Liu C, Zhang C, Lu G, Li W, Liu J, Chen ZJ, Liu H
eLife 2020 May 6;9
eLife 2020 May 6;9
Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.
Li Y, Tang L, Yue J, Gou X, Lin A, Weatherbee SD, Wu X
EMBO reports 2020 May 6;21(5):e48566
EMBO reports 2020 May 6;21(5):e48566
GDF15 knockdown promotes erastin-induced ferroptosis by decreasing SLC7A11 expression.
Chen L, Qiao L, Bian Y, Sun X
Biochemical and biophysical research communications 2020 May 28;526(2):293-299
Biochemical and biophysical research communications 2020 May 28;526(2):293-299
Role of Clostridium perfringens Enterotoxin on YAP Activation in Colonic Sessile Serrated Adenoma/ Polyps with Dysplasia.
Fujiwara-Tani R, Fujii K, Mori S, Kishi S, Sasaki T, Ohmori H, Nakashima C, Kawahara I, Nishiguchi Y, Mori T, Sho M, Kondoh M, Luo Y, Kuniyasu H
International journal of molecular sciences 2020 May 28;21(11)
International journal of molecular sciences 2020 May 28;21(11)
Second-order optimized regularized structured illumination microscopy (sorSIM) for high-quality and rapid super resolution image reconstruction with low signal level.
Yu W, Li Y, Jooken S, Deschaume O, Liu F, Wang S, Bartic C
Optics express 2020 May 25;28(11):16708-16724
Optics express 2020 May 25;28(11):16708-16724
Autophagy suppression of trophoblast cells induces pregnancy loss by activating decidual NK cytotoxicity and inhibiting trophoblast invasion.
Tan HX, Yang SL, Li MQ, Wang HY
Cell communication and signaling : CCS 2020 May 12;18(1):73
Cell communication and signaling : CCS 2020 May 12;18(1):73
PIM1 inhibitor synergizes the anti-tumor effect of osimertinib via STAT3 dephosphorylation in EGFR-mutant non-small cell lung cancer.
Sun Z, Zeng L, Zhang M, Zhang Y, Yang N
Annals of translational medicine 2020 Mar;8(6):366
Annals of translational medicine 2020 Mar;8(6):366
Ophiopogonin D promotes bone regeneration by stimulating CD31(hi) EMCN(hi) vessel formation.
Yang M, Li CJ, Xiao Y, Guo Q, Huang Y, Su T, Luo XH, Jiang TJ
Cell proliferation 2020 Mar;53(3):e12784
Cell proliferation 2020 Mar;53(3):e12784
Elevated myocardial SORBS2 and the underlying implications in left ventricular noncompaction cardiomyopathy.
Li C, Liu F, Liu S, Pan H, Du H, Huang J, Xie Y, Li Y, Zhao R, Wei Y
EBioMedicine 2020 Mar;53:102695
EBioMedicine 2020 Mar;53:102695
Inhibition of UCHL1 by LDN-57444 attenuates Ang II-Induced atrial fibrillation in mice.
Bi HL, Zhang YL, Yang J, Shu Q, Yang XL, Yan X, Chen C, Li Z, Li HH
Hypertension research : official journal of the Japanese Society of Hypertension 2020 Mar;43(3):168-177
Hypertension research : official journal of the Japanese Society of Hypertension 2020 Mar;43(3):168-177
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.
Ren Y, Xu X, Mao CY, Han KK, Xu YJ, Cao BY, Zhang ZB, Sethi G, Tang XW, Mao XL
Acta pharmacologica Sinica 2020 Mar;41(3):394-403
Acta pharmacologica Sinica 2020 Mar;41(3):394-403
Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation.
Kimura Y, Yanagida T, Onda A, Tsukui D, Hosoyamada M, Kono H
Arteriosclerosis, thrombosis, and vascular biology 2020 Mar;40(3):570-582
Arteriosclerosis, thrombosis, and vascular biology 2020 Mar;40(3):570-582
AIM2 promotes the development of non-small cell lung cancer by modulating mitochondrial dynamics.
Qi M, Dai D, Liu J, Li Z, Liang P, Wang Y, Cheng L, Zhan Y, An Z, Song Y, Yang Y, Yan X, Xiao H, Shao H
Oncogene 2020 Mar;39(13):2707-2723
Oncogene 2020 Mar;39(13):2707-2723
lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCF(β-TRCP)-Mediated Degradation of NRF2 in Pancreatic Cancer.
Yang Q, Li K, Huang X, Zhao C, Mei Y, Li X, Jiao L, Yang H
Molecular therapy. Nucleic acids 2020 Mar 6;19:974-985
Molecular therapy. Nucleic acids 2020 Mar 6;19:974-985
Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promotes colorectal cancer progression.
Liu Q, Yang C, Wang S, Shi D, Wei C, Song J, Lin X, Dou R, Bai J, Xiang Z, Huang S, Liu K, Xiong B
Cell communication and signaling : CCS 2020 Mar 30;18(1):51
Cell communication and signaling : CCS 2020 Mar 30;18(1):51
Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development.
Song NN, Ma P, Zhang Q, Zhang L, Wang H, Zhang L, Zhu L, He CH, Mao B, Ding YQ
Development (Cambridge, England) 2020 Mar 30;147(6)
Development (Cambridge, England) 2020 Mar 30;147(6)
MACF1 promotes preosteoblast migration by mediating focal adhesion turnover through EB1.
Su P, Yin C, Li D, Yang C, Wang X, Pei J, Tian Y, Qian A
Biology open 2020 Mar 24;9(3)
Biology open 2020 Mar 24;9(3)
Dietary Supplemented Curcumin Improves Meat Quality and Antioxidant Status of Intrauterine Growth Retardation Growing Pigs via Nrf2 Signal Pathway.
Zhang L, Zhang J, Yan E, He J, Zhong X, Zhang L, Wang C, Wang T
Animals : an open access journal from MDPI 2020 Mar 24;10(3)
Animals : an open access journal from MDPI 2020 Mar 24;10(3)
PHLDA1 is a new therapeutic target of oxidative stress and ischemia reperfusion-induced myocardial injury.
Guo Y, Jia P, Chen Y, Yu H, Xin X, Bao Y, Yang H, Wu N, Sun Y, Jia D
Life sciences 2020 Mar 15;245:117347
Life sciences 2020 Mar 15;245:117347
Dlgap1 negatively regulates browning of white fat cells through effects on cell proliferation and apoptosis.
Zhang J, Yang J, Yang N, Ma J, Lu D, Dong Y, Liang H, Liu D, Cang M
Lipids in health and disease 2020 Mar 13;19(1):39
Lipids in health and disease 2020 Mar 13;19(1):39
BRCA1 protects cardiac microvascular endothelial cells against irradiation by regulating p21-mediated cell cycle arrest.
Zeng ZM, Du HY, Xiong L, Zeng XL, Zhang P, Cai J, Huang L, Liu AW
Life sciences 2020 Mar 1;244:117342
Life sciences 2020 Mar 1;244:117342
AFF1 inhibits adipogenic differentiation via targeting TGM2 transcription.
Chen Y, Wang Y, Lin W, Sheng R, Wu Y, Xu R, Zhou C, Yuan Q
Cell proliferation 2020 Jun;53(6):e12831
Cell proliferation 2020 Jun;53(6):e12831
Proanthocyanidins Promote Osteogenic Differentiation of Human Periodontal Ligament Fibroblasts in Inflammatory Environment Via Suppressing NF-κB Signal Pathway.
Huang J, Liu L, Jin S, Zhang Y, Zhang L, Li S, Song A, Yang P
Inflammation 2020 Jun;43(3):892-902
Inflammation 2020 Jun;43(3):892-902
Transient inhibition of rDNA transcription in donor cells improves ribosome biogenesis and preimplantation development of embryos derived from somatic cell nuclear transfer.
Liao C, Pang N, Liu Z, Lei L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8283-8295
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8283-8295
Disregulation of Autophagy in the Transgenerational Cc2d1a Mouse Model of Autism.
Dana H, Bayramov KK, Delibaşı N, Tahtasakal R, Bayramov R, Hamurcu Z, Sener EF
Neuromolecular medicine 2020 Jun;22(2):239-249
Neuromolecular medicine 2020 Jun;22(2):239-249
Ophiocordyceps lanpingensis polysaccharides attenuate pulmonary fibrosis in mice.
Zhou S, Zhou Y, Yu J, Du Y, Tan Y, Ke Y, Wang J, Han B, Ge F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110058
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110058
Downregulated miR-150 in bone marrow mesenchymal stem cells attenuates the apoptosis of LPS-stimulated RAW264.7 via MTCH2-dependent mitochondria transfer.
Zhou X, Zhang K, He Z, Deng Y, Gao Y
Biochemical and biophysical research communications 2020 Jun 4;526(3):560-567
Biochemical and biophysical research communications 2020 Jun 4;526(3):560-567
Uncoupling DNA damage from chromatin damage to detoxify doxorubicin.
Qiao X, van der Zanden SY, Wander DPA, Borràs DM, Song JY, Li X, van Duikeren S, van Gils N, Rutten A, van Herwaarden T, van Tellingen O, Giacomelli E, Bellin M, Orlova V, Tertoolen LGJ, Gerhardt S, Akkermans JJ, Bakker JM, Zuur CL, Pang B, Smits AM, Mummery CL, Smit L, Arens R, Li J, Overkleeft HS, Neefjes J
Proceedings of the National Academy of Sciences of the United States of America 2020 Jun 30;117(26):15182-15192
Proceedings of the National Academy of Sciences of the United States of America 2020 Jun 30;117(26):15182-15192
Ubiquitin C-terminal hydrolase L1 (UCHL1) regulates post-myocardial infarction cardiac fibrosis through glucose-regulated protein of 78 kDa (GRP78).
Lei Q, Yi T, Li H, Yan Z, Lv Z, Li G, Wang Y
Scientific reports 2020 Jun 30;10(1):10604
Scientific reports 2020 Jun 30;10(1):10604
Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation.
Tang D, Liu X, Chen K, Li Z, Dai Y, Xu J, Zhang HT, Gao X, Liu L
Aging 2020 Jun 27;12(13):13297-13317
Aging 2020 Jun 27;12(13):13297-13317
Immune activation of murine RAW264.7 macrophages by sonicated and alkalized paramylon from Euglena gracilis.
Guo Q, Bi D, Wu M, Yu B, Hu L, Liu C, Gu L, Zhu H, Lei A, Xu X, Wang J
BMC microbiology 2020 Jun 19;20(1):171
BMC microbiology 2020 Jun 19;20(1):171
Induction of ASC pyroptosis requires gasdermin D or caspase-1/11-dependent mediators and IFNβ from pyroptotic macrophages.
Zhang C, Zhao C, Chen X, Tao R, Wang S, Meng G, Liu X, Shao C, Su X
Cell death & disease 2020 Jun 18;11(6):470
Cell death & disease 2020 Jun 18;11(6):470
Fine particulate matter increases airway hyperresponsiveness through kallikrein-bradykinin pathway.
Cao X, Wang M, Li J, Luo Y, Li R, Yan X, Zhang H
Ecotoxicology and environmental safety 2020 Jun 1;195:110491
Ecotoxicology and environmental safety 2020 Jun 1;195:110491
Modification of PLGA Scaffold by MSC-Derived Extracellular Matrix Combats Macrophage Inflammation to Initiate Bone Regeneration via TGF-β-Induced Protein.
Deng M, Tan J, Hu C, Hou T, Peng W, Liu J, Yu B, Dai Q, Zhou J, Yang Y, Dong R, Ruan C, Dong S, Xu J
Advanced healthcare materials 2020 Jul;9(13):e2000353
Advanced healthcare materials 2020 Jul;9(13):e2000353
Poricoic acid A activates AMPK to attenuate fibroblast activation and abnormal extracellular matrix remodelling in renal fibrosis.
Chen DQ, Wang YN, Vaziri ND, Chen L, Hu HH, Zhao YY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jul;72:153232
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Jul;72:153232
Expression and significance of T-cell immunoglobulin mucin molecule 3 and its ligand galectin-9 in patients with adenomyosis.
Huang P, Lv C, Zhang C, Feng H, Li C, Zhang H, Zhao X, Li M
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2020 Jul;36(7):605-610
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2020 Jul;36(7):605-610
EHF promotes colorectal carcinoma progression by activating TGF-β1 transcription and canonical TGF-β signaling.
Wang L, Ai M, Nie M, Zhao L, Deng G, Hu S, Han Y, Zeng W, Wang Y, Yang M, Wang S
Cancer science 2020 Jul;111(7):2310-2324
Cancer science 2020 Jul;111(7):2310-2324
Human alkaline ceramidase 2 promotes the growth, invasion, and migration of hepatocellular carcinoma cells via sphingomyelin phosphodiesterase acid-like 3B.
Liu B, Xiao J, Dong M, Qiu Z, Jin J
Cancer science 2020 Jul;111(7):2259-2274
Cancer science 2020 Jul;111(7):2259-2274
RNA-seq analysis of the key long noncoding RNAs and mRNAs related to cognitive impairment after cardiac arrest and cardiopulmonary resuscitation.
Chen C, Liu C, Niu Z, Li M, Zhang Y, Gao R, Chen H, Wang Q, Zhang S, Zhou R, Gan L, Zhang Z, Zhu T, Yu H, Liu J
Aging 2020 Jul 21;12(14):14490-14505
Aging 2020 Jul 21;12(14):14490-14505
Clinically relevant high levels of human C-reactive protein induces endothelial dysfunction and hypertension by inhibiting the AMPK-eNOS axis.
Cheng L, Wang L, Guo M, He J, Deng Y, Liu J, Wei Y, Wang C, Zhou J, Ma L, Song Q, Yuan Z, Wu Y
Clinical science (London, England : 1979) 2020 Jul 17;134(13):1805-1819
Clinical science (London, England : 1979) 2020 Jul 17;134(13):1805-1819
RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins.
Hu X, Wang L, Wang Y, Ji J, Li J, Wang Z, Li C, Zhang Y, Zhang ZR
Molecular cell 2020 Jul 16;79(2):320-331.e9
Molecular cell 2020 Jul 16;79(2):320-331.e9
Downregulation of the circadian rhythm regulator HLF promotes multiple-organ distant metastases in non-small cell lung cancer through PPAR/NF-κb signaling.
Chen J, Liu A, Lin Z, Wang B, Chai X, Chen S, Lu W, Zheng M, Cao T, Zhong M, Li R, Wu M, Lu Z, Pang W, Huang W, Xiao L, Lin D, Wang Z, Lei F, Chen X, Long W, Zheng Y, Chen Q, Zeng J, Ren D, Li J, Zhang X, Huang Y
Cancer letters 2020 Jul 10;482:56-71
Cancer letters 2020 Jul 10;482:56-71
Loss of ZC4H2 and RNF220 Inhibits Neural Stem Cell Proliferation and Promotes Neuronal Differentiation.
Zhang L, Ye M, Zhu L, Cha J, Li C, Yao YG, Mao B
Cells 2020 Jul 1;9(7)
Cells 2020 Jul 1;9(7)
Design, synthesis and biological evaluation of homoerythrina alkaloid derivatives bearing a triazole moiety as PARP-1 inhibitors and as potential antitumor drugs.
Li S, Li XY, Zhang TJ, Kamara MO, Liang JW, Zhu J, Meng FH
Bioorganic chemistry 2020 Jan;94:103385
Bioorganic chemistry 2020 Jan;94:103385
Dichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway.
Liang Y, Hou L, Li L, Li L, Zhu L, Wang Y, Huang X, Hou Y, Zhu D, Zou H, Gu Y, Weng X, Wang Y, Li Y, Wu T, Yao M, Gross I, Gaiddon C, Luo M, Wang J, Meng X
Oncogene 2020 Jan;39(2):469-485
Oncogene 2020 Jan;39(2):469-485
Sema7A, a brain immune regulator, regulates seizure activity in PTZ-kindled epileptic rats.
Deng J, Xu T, Yang J, Zhang KM, Li Q, Yu XY, Li R, Fu J, Jiang Q, Ma JX, Chen YM
CNS neuroscience & therapeutics 2020 Jan;26(1):101-116
CNS neuroscience & therapeutics 2020 Jan;26(1):101-116
Poly (ADP-ribosylation) of HMGB1 facilitates its acetylation and promotes HMGB1 translocation-associated chemotherapy-induced autophagy in leukaemia cells.
Li Y, Xie J, Li X, Fang J
Oncology letters 2020 Jan;19(1):368-378
Oncology letters 2020 Jan;19(1):368-378
Centrosome Amplification in Cancer Disrupts Autophagy and Sensitizes to Autophagy Inhibition.
Denu RA, Kaur G, Sass MM, Lakkaraju A, Burkard ME
Molecular cancer research : MCR 2020 Jan;18(1):33-45
Molecular cancer research : MCR 2020 Jan;18(1):33-45
Gentiopicroside activates the bile acid receptor Gpbar1 (TGR5) to repress NF-kappaB pathway and ameliorate diabetic nephropathy.
Xiao H, Sun X, Liu R, Chen Z, Lin Z, Yang Y, Zhang M, Liu P, Quan S, Huang H
Pharmacological research 2020 Jan;151:104559
Pharmacological research 2020 Jan;151:104559
Knockdown of Rab9 Suppresses the Progression of Gastric Cancer Through Regulation of Akt Signaling Pathway.
Zhu Y, Shi F, Wang M, Ding J
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820915958
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820915958
MicroRNA-547-5p-mediated interleukin-33/suppressor of tumorigenicity 2 signaling underlies the genesis and maintenance of neuropathic pain and is targeted by the therapy with bone marrow stromal cells.
Zhou J, Zhuang T, Ma P, Shan L, Sun XD, Gong S, Tao J, Yu XM, Jiang X
Molecular pain 2020 Jan-Dec;16:1744806920931737
Molecular pain 2020 Jan-Dec;16:1744806920931737
CXCL12/CXCR4 signaling induced itch and pain sensation in a murine model of allergic contact dermatitis.
Su W, Yu J, Liu Q, Ma L, Huang Y
Molecular pain 2020 Jan-Dec;16:1744806920926426
Molecular pain 2020 Jan-Dec;16:1744806920926426
5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl) imidazol (BZML) targets tubulin and DNA to induce anticancer activity and overcome multidrug resistance in colorectal cancer cells.
Bai Z, Liu X, Guan Q, Ding N, Wei Q, Tong B, Zhao M, Zhang W, Ma L
Chemico-biological interactions 2020 Jan 5;315:108886
Chemico-biological interactions 2020 Jan 5;315:108886
The Capsid Protein of Semliki Forest Virus Antagonizes RNA Interference in Mammalian Cells.
Qian Q, Zhou H, Shu T, Mu J, Fang Y, Xu J, Li T, Kong J, Qiu Y, Zhou X
Journal of virology 2020 Jan 17;94(3)
Journal of virology 2020 Jan 17;94(3)
Inhibitory Activity of a Scorpion Defensin BmKDfsin3 against Hepatitis C Virus.
Cheng Y, Sun F, Li S, Gao M, Wang L, Sarhan M, Abdel-Rahman MA, Li W, Kwok HF, Wu Y, Cao Z
Antibiotics (Basel, Switzerland) 2020 Jan 17;9(1)
Antibiotics (Basel, Switzerland) 2020 Jan 17;9(1)
The nuclear translocation of transketolase inhibits the farnesoid receptor expression by promoting the binding of HDAC3 to FXR promoter in hepatocellular carcinoma cell lines.
Li M, Zhang X, Lu Y, Meng S, Quan H, Hou P, Tong P, Chai D, Gao X, Zheng J, Tong X, Bai J
Cell death & disease 2020 Jan 16;11(1):31
Cell death & disease 2020 Jan 16;11(1):31
RETRACTED: Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis.
Guo SS, Liu R, Wen YF, Liu LT, Yuan L, Li YX, Li Y, Hao WW, Peng JY, Chen DN, Tang QN, Sun XS, Guo L, Mo HY, Qian CN, Zeng MS, Bei JX, Sun SY, Chen QY, Tang LQ, Mai HQ
Cancer letters 2020 Jan 1;468:27-40
Cancer letters 2020 Jan 1;468:27-40
ING4 alleviated lipopolysaccharide-induced inflammation by regulating the NF-κB pathway via a direct interaction with SIRT1.
Yang Y, Liu Y, He X, Yang F, Han S, Qin A, Wu G, Liu M, Li Z, Wang J, Yang X, Hu D
Immunology and cell biology 2020 Feb;98(2):127-137
Immunology and cell biology 2020 Feb;98(2):127-137
Biallelic mutation of HSD17B4 induces middle age-onset spinocerebellar ataxia.
Matsuda Y, Morino H, Miyamoto R, Kurashige T, Kume K, Mizuno N, Kanaya Y, Tada Y, Ohsawa R, Yokota K, Shimozawa N, Maruyama H, Kawakami H
Neurology. Genetics 2020 Feb;6(1):e396
Neurology. Genetics 2020 Feb;6(1):e396
Functional analysis of natural PCSK9 mutants in modern and archaic humans.
Mikaeeli S, Susan-Resiga D, Girard E, Ben Djoudi Ouadda A, Day R, Prost S, Seidah NG
The FEBS journal 2020 Feb;287(3):515-528
The FEBS journal 2020 Feb;287(3):515-528
Expanding the retinal phenotype of RP1: from retinitis pigmentosa to a novel and singular macular dystrophy.
Riera M, Abad-Morales V, Navarro R, Ruiz-Nogales S, Méndez-Vendrell P, Corcostegui B, Pomares E
The British journal of ophthalmology 2020 Feb;104(2):173-181
The British journal of ophthalmology 2020 Feb;104(2):173-181
The identification and characterisation of autophagy inhibitors from the published kinase inhibitor sets.
Zachari M, Rainard JM, Pandarakalam GC, Robinson L, Gillespie J, Rajamanickam M, Hamon V, Morrison A, Ganley IG, McElroy SP
The Biochemical journal 2020 Feb 28;477(4):801-814
The Biochemical journal 2020 Feb 28;477(4):801-814
Hypermethylation of UCHL1 Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN).
Zhao Y, Lei Y, He SW, Li YQ, Wang YQ, Hong XH, Liang YL, Li JY, Chen Y, Luo WJ, Zhang PP, Yang XJ, He QM, Ma J, Liu N, Tang LL
Cells 2020 Feb 27;9(3)
Cells 2020 Feb 27;9(3)
Neurotoxicity and biomarkers of zinc oxide nanoparticles in main functional brain regions and dopaminergic neurons.
Liu H, Yang H, Fang Y, Li K, Tian L, Liu X, Zhang W, Tan Y, Lai W, Bian L, Lin B, Xi Z
The Science of the total environment 2020 Feb 25;705:135809
The Science of the total environment 2020 Feb 25;705:135809
WDR62 is a novel participator in spindle migration and asymmetric cytokinesis during mouse oocyte meiotic maturation.
Wang YS, Jiao XF, Chen F, Wu D, Ding ZM, Miao YL, Huo LJ
Experimental cell research 2020 Feb 1;387(1):111773
Experimental cell research 2020 Feb 1;387(1):111773
Bnip3 mediates doxorubicin-induced cardiomyocyte pyroptosis via caspase-3/GSDME.
Zheng X, Zhong T, Ma Y, Wan X, Qin A, Yao B, Zou H, Song Y, Yin D
Life sciences 2020 Feb 1;242:117186
Life sciences 2020 Feb 1;242:117186
Novel poricoic acids attenuate renal fibrosis through regulating redox signalling and aryl hydrocarbon receptor activation.
Wang M, Hu HH, Chen YY, Chen L, Wu XQ, Zhao YY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Dec;79:153323
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Dec;79:153323
Asiaticoside Inhibits Neuronal Apoptosis and Promotes Functional Recovery After Spinal Cord Injury in Rats.
Fan L, Li X, Liu T
Journal of molecular neuroscience : MN 2020 Dec;70(12):1988-1996
Journal of molecular neuroscience : MN 2020 Dec;70(12):1988-1996
Aster-B coordinates with Arf1 to regulate mitochondrial cholesterol transport.
Andersen JP, Zhang J, Sun H, Liu X, Liu J, Nie J, Shi Y
Molecular metabolism 2020 Dec;42:101055
Molecular metabolism 2020 Dec;42:101055
ZNF582 hypermethylation promotes metastasis of nasopharyngeal carcinoma by regulating the transcription of adhesion molecules Nectin-3 and NRXN3.
Zhao Y, Hong XH, Li K, Li YQ, Li YQ, He SW, Zhang PP, Li JY, Li Q, Liang YL, Chen Y, Ma J, Liu N, Chen YP
Cancer communications (London, England) 2020 Dec;40(12):721-737
Cancer communications (London, England) 2020 Dec;40(12):721-737
Synthesis and biological evaluation of (3/4-(pyrimidin-2-ylamino)benzoyl)-based hydrazine-1-carboxamide/carbothioamide derivatives as novel RXRα antagonists.
Qin J, Liu J, Wu C, Xu J, Tang B, Guo K, Chen X, Liu W, Wu T, Zhou H, Fang M, Wu Z
Journal of enzyme inhibition and medicinal chemistry 2020 Dec;35(1):880-896
Journal of enzyme inhibition and medicinal chemistry 2020 Dec;35(1):880-896
EBV-miR-BART12 accelerates migration and invasion in EBV-associated cancer cells by targeting tubulin polymerization-promoting protein 1.
Wu Y, Wang D, Wei F, Xiong F, Zhang S, Gong Z, Shi L, Li X, Xiang B, Ma J, Deng H, He Y, Liao Q, Zhang W, Li X, Li Y, Guo C, Zeng Z, Li G, Xiong W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16205-16223
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16205-16223
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
He X, Li M, Yu H, Liu G, Wang N, Yin C, Tu Q, Narla G, Tao Y, Cheng S, Yin H
PLoS biology 2020 Dec;18(12):e3000803
PLoS biology 2020 Dec;18(12):e3000803
Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.
Li Y, Bai L, Yu H, Cai D, Wang X, Huang B, Peng S, Huang M, Cao G, Kaz AM, Grady WM, Wang J, Luo Y
Cancer research 2020 Dec 1;80(23):5203-5215
Cancer research 2020 Dec 1;80(23):5203-5215
PhospholipaseCγ1/calcium-dependent membranous localization of Gsdmd-N drives endothelial pyroptosis, contributing to lipopolysaccharide-induced fatal outcome.
Liu H, Tang D, Zhou X, Yang X, Chen AF
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1482-H1495
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1482-H1495
Macrophage-stimulating activity of European eel (Anguilla anguilla) peptides in RAW264.7 cells mediated via NF-κB and MAPK signaling pathways.
Yao L, Yang P, Luo W, Li S, Wu Y, Cai N, Bi D, Li H, Han Q, Xu X
Food & function 2020 Dec 1;11(12):10968-10978
Food & function 2020 Dec 1;11(12):10968-10978
Naked antisense double-stranded DNA oligonucleotide efficiently suppresses BCR-ABL positive leukemic cells.
Hoshiko T, Kubota Y, Akisawa T, Watanabe T, Tanigawara K, Yano J, Kimura S
Investigational new drugs 2020 Aug;38(4):1012-1019
Investigational new drugs 2020 Aug;38(4):1012-1019
Corticosterone Induced the Increase of proBDNF in Primary Hippocampal Neurons Via Endoplasmic Reticulum Stress.
Liu Y, Zou GJ, Tu BX, Hu ZL, Luo C, Cui YH, Xu Y, Li F, Dai RP, Bi FF, Li CQ
Neurotoxicity research 2020 Aug;38(2):370-384
Neurotoxicity research 2020 Aug;38(2):370-384
Mass spectrometry-based proteomic capture of proteins bound to the MACC1 promoter in colon cancer.
Huang Y, Xiang Y, Xie Z, Cai Y, Yang Q, Huang H, Chen Z, Xiao Z, He Q
Clinical & experimental metastasis 2020 Aug;37(4):477-487
Clinical & experimental metastasis 2020 Aug;37(4):477-487
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
Li A, Zhang N, Zhao Z, Chen Y, Zhang L
Oncology letters 2020 Aug;20(2):1535-1544
Oncology letters 2020 Aug;20(2):1535-1544
Super-enhancer-driven metabolic reprogramming promotes cystogenesis in autosomal dominant polycystic kidney disease.
Mi Z, Song Y, Cao X, Lu Y, Liu Z, Zhu X, Geng M, Sun Y, Lan B, He C, Xiong H, Zhang L, Chen Y
Nature metabolism 2020 Aug;2(8):717-731
Nature metabolism 2020 Aug;2(8):717-731
Brain-Specific Serine-47 Modification of Cytochrome c Regulates Cytochrome c Oxidase Activity Attenuating ROS Production and Cell Death: Implications for Ischemia/Reperfusion Injury and Akt Signaling.
Kalpage HA, Wan J, Morse PT, Lee I, Hüttemann M
Cells 2020 Aug 6;9(8)
Cells 2020 Aug 6;9(8)
Mechanical Ring Interfaces between Adherens Junction and Contractile Actomyosin to Coordinate Entotic Cell-in-Cell Formation.
Wang M, Niu Z, Qin H, Ruan B, Zheng Y, Ning X, Gu S, Gao L, Chen Z, Wang X, Huang H, Ma L, Sun Q
Cell reports 2020 Aug 25;32(8):108071
Cell reports 2020 Aug 25;32(8):108071
Regulation of Female Folliculogenesis by Tsp1a in Nile Tilapia (Oreochromis niloticus).
Jie M, Ma H, Zhou L, Wu J, Li M, Liu X, Wang D
International journal of molecular sciences 2020 Aug 16;21(16)
International journal of molecular sciences 2020 Aug 16;21(16)
Plakoglobin is involved in cytoskeletal rearrangement of podocytes under the regulation of UCH-L1.
Fang Y, Li F, Qi C, Mao X, Xu Y, Zhao Z, Wu H, Zhang Z
Biochemical and biophysical research communications 2020 Aug 13;529(1):112-118
Biochemical and biophysical research communications 2020 Aug 13;529(1):112-118
Pum2 mediates Sirt1 mRNA decay and exacerbates hypoxia/reoxygenation-induced cardiomyocyte apoptosis.
Cao Y, Liu C, Wang Q, Wang W, Tao E, Wan L
Experimental cell research 2020 Aug 1;393(1):112058
Experimental cell research 2020 Aug 1;393(1):112058
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
Huang J, Diao G, Zhang Q, Chen Y, Han J, Guo J
International journal of oncology 2020 Apr;56(4):921-931
International journal of oncology 2020 Apr;56(4):921-931
Sirtuin 2 Inhibition Attenuates Sevoflurane-Induced Learning and Memory Deficits in Developing Rats via Modulating Microglial Activation.
Wu Z, Zhang Y, Zhang Y, Zhao P
Cellular and molecular neurobiology 2020 Apr;40(3):437-446
Cellular and molecular neurobiology 2020 Apr;40(3):437-446
Antibiotic tigecycline inhibits cell proliferation, migration and invasion via down-regulating CCNE2 in pancreatic ductal adenocarcinoma.
Yang J, Dong Z, Ren A, Fu G, Zhang K, Li C, Wang X, Cui H
Journal of cellular and molecular medicine 2020 Apr;24(7):4245-4260
Journal of cellular and molecular medicine 2020 Apr;24(7):4245-4260
C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis.
Wang M, Wang H, Tao Z, Xia Q, Hao Z, Prehn JHM, Zhen X, Wang G, Ying Z
Aging cell 2020 Apr;19(4):e13126
Aging cell 2020 Apr;19(4):e13126
Alternatively Polarized Macrophages Regulate the Growth and Differentiation of Ependymal Stem Cells through the SIRT2 Pathway.
Ma Y, Deng M, Zhao XQ, Liu M
Experimental neurobiology 2020 Apr 30;29(2):150-163
Experimental neurobiology 2020 Apr 30;29(2):150-163
SIRT6-PARP1 is involved in HMGB1 polyADP-ribosylation and acetylation and promotes chemotherapy-induced autophagy in leukemia.
Kong Q, Li Y, Liang Q, Xie J, Li X, Fang J
Cancer biology & therapy 2020 Apr 2;21(4):320-331
Cancer biology & therapy 2020 Apr 2;21(4):320-331
Hepatic CD147 knockout modulates liver steatosis and up-regulates autophagy in high-fat-diet-induced NAFLD mice.
Lou J, Li C, Li ZS, Zhang T, Chen ZN, Bian H
Biochemical and biophysical research communications 2020 Apr 16;524(4):1010-1017
Biochemical and biophysical research communications 2020 Apr 16;524(4):1010-1017
Interleukin-17 suppresses grass carp reovirus infection in Ctenopharyngodon idellus kidney cells by activating NF-κB signaling.
Zhang Y, Zhang X, Liang Z, Dai K, Zhu M, Zhang M, Pan J, Xue R, Cao G, Tang J, Song X, Hu X, Gong C
Aquaculture (Amsterdam, Netherlands) 2020 Apr 15;520:734969
Aquaculture (Amsterdam, Netherlands) 2020 Apr 15;520:734969
Betulinic Acid-Mediated Tuning of PERK/CHOP Signaling by Sp1 Inhibition as a Novel Therapeutic Strategy for Glioblastoma.
Lo WL, Hsu TI, Yang WB, Kao TJ, Wu MH, Huang YN, Yeh SH, Chuang JY
Cancers 2020 Apr 15;12(4)
Cancers 2020 Apr 15;12(4)
Ovarian cancer cell-secreted exosomal miR-205 promotes metastasis by inducing angiogenesis.
He L, Zhu W, Chen Q, Yuan Y, Wang Y, Wang J, Wu X
Theranostics 2019;9(26):8206-8220
Theranostics 2019;9(26):8206-8220
Targeting JUN, CEBPB, and HDAC3: A Novel Strategy to Overcome Drug Resistance in Hypoxic Glioblastoma.
Gao Y, Liu B, Feng L, Sun B, He S, Yang Y, Wu G, E G, Liu C, Gao Y, Zhang E, Zhu B
Frontiers in oncology 2019;9:33
Frontiers in oncology 2019;9:33
Identification of Aloperine as an anti-apoptotic Bcl2 protein inhibitor in glioma cells.
Xu Z, Wang X, Chen X, Zeng S, Qian L, Wei J, Gong Z, Yan Y
PeerJ 2019;7:e7652
PeerJ 2019;7:e7652
Cardiac proteomics reveals the potential mechanism of microtubule associated protein 4 phosphorylation-induced mitochondrial dysfunction.
Li L, Zhang J, Zhang Q, Huang Y, Hu J
Burns & trauma 2019;7:8
Burns & trauma 2019;7:8
Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence.
Li Y, Li X, Cao M, Jiang Y, Yan J, Liu Z, Yang R, Chen X, Sun P, Xiang R, Wang L, Shi Y
Signal transduction and targeted therapy 2019;4:50
Signal transduction and targeted therapy 2019;4:50
Myocardial Adipose Triglyceride Lipase Overexpression Protects against Burn-Induced Cardiac Lipid Accumulation and Injury.
Li L, Zhang X, Zhang Q, Jia J, Zhang J, Zhang D, Song H, Chen B, Hu J, Huang Y
Oxidative medicine and cellular longevity 2019;2019:6428924
Oxidative medicine and cellular longevity 2019;2019:6428924
Impaired Mitochondrial Fusion and Oxidative Phosphorylation Triggered by High Glucose Is Mediated by Tom22 in Endothelial Cells.
Zeng Y, Pan Q, Wang X, Li D, Lin Y, Man F, Xiao F, Guo L
Oxidative medicine and cellular longevity 2019;2019:4508762
Oxidative medicine and cellular longevity 2019;2019:4508762
Cul4a as a New Interaction Protein of PARP1 Inhibits Oxidative Stress-Induced H9c2 Cell Apoptosis.
Ye N, Zhang N, Zhang Y, Qian H, Wu B, Sun Y
Oxidative medicine and cellular longevity 2019;2019:4273261
Oxidative medicine and cellular longevity 2019;2019:4273261
VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway.
Xu X, Zong Y, Gao Y, Sun X, Zhao H, Luo W, Jia S
BioMed research international 2019;2019:3909102
BioMed research international 2019;2019:3909102
Cancer-associated fibroblasts promote colorectal cancer progression by secreting CLEC3B.
Zhu HF, Zhang XH, Gu CS, Zhong Y, Long T, Ma YD, Hu ZY, Li ZG, Wang XY
Cancer biology & therapy 2019;20(7):967-978
Cancer biology & therapy 2019;20(7):967-978
SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.
Yang Z, Yu W, Huang R, Ye M, Min Z
Cancer cell international 2019;19:17
Cancer cell international 2019;19:17
Microtubule-associated protein 4 phosphorylation regulates epidermal keratinocyte migration and proliferation.
Zhang J, Li L, Zhang Q, Wang W, Zhang D, Jia J, Lv Y, Yuan H, Song H, Xiang F, Hu J, Huang Y
International journal of biological sciences 2019;15(9):1962-1976
International journal of biological sciences 2019;15(9):1962-1976
Histone Demethylase UTX is an Essential Factor for Zygotic Genome Activation and Regulates Zscan4 Expression in Mouse Embryos.
Bai L, Yang L, Zhao C, Song L, Liu X, Bai C, Su G, Wei Z, Li G
International journal of biological sciences 2019;15(11):2363-2372
International journal of biological sciences 2019;15(11):2363-2372
Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9.
Chen KY, Chen CC, Chang YC, Chang MC
PloS one 2019;14(7):e0219317
PloS one 2019;14(7):e0219317
Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells.
Chadchankar J, Korboukh V, Conway LC, Wobst HJ, Walker CA, Doig P, Jacobsen SJ, Brandon NJ, Moss SJ, Wang Q
PloS one 2019;14(11):e0225145
PloS one 2019;14(11):e0225145
Osteoprotegerin promotes islet β cell proliferation in intrauterine growth retardation rats through the PI3K/AKT/FoxO1 pathway.
Tang S, Xin Y, Yang M, Zhang D, Xu C
International journal of clinical and experimental pathology 2019;12(6):2324-2338
International journal of clinical and experimental pathology 2019;12(6):2324-2338
GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer.
Han N, Yuan F, Xian P, Liu N, Liu J, Zhang H, Zhang H, Yao K, Yuan G
OncoTargets and therapy 2019;12:7591-7599
OncoTargets and therapy 2019;12:7591-7599
Osteoglycin (OGN) Inhibits Cell Proliferation and Invasiveness in Breast Cancer via PI3K/Akt/mTOR Signaling Pathway.
Xu T, Zhang R, Dong M, Zhang Z, Li H, Zhan C, Li X
OncoTargets and therapy 2019;12:10639-10650
OncoTargets and therapy 2019;12:10639-10650
Identification of the Potential Key Long Non-coding RNAs in Aged Mice With Postoperative Cognitive Dysfunction.
Li M, Chen C, Zhang W, Gao R, Wang Q, Chen H, Zhang S, Mao X, Leblanc M, Behensky A, Zhang Z, Gan L, Yu H, Zhu T, Liu J
Frontiers in aging neuroscience 2019;11:181
Frontiers in aging neuroscience 2019;11:181
Dichloroacetate Overcomes Oxaliplatin Chemoresistance in Colorectal Cancer through the miR-543/PTEN/Akt/mTOR Pathway.
Liang Y, Zhu D, Zhu L, Hou Y, Hou L, Huang X, Li L, Wang Y, Li L, Zou H, Wu T, Yao M, Wang J, Meng X
Journal of Cancer 2019;10(24):6037-6047
Journal of Cancer 2019;10(24):6037-6047
Qingpeng Ointment Ameliorates Inflammatory Responses and Dysregulation of Itch-Related Molecules for Its Antipruritic Effects in Experimental Allergic Contact Dermatitis.
Gong X, Xiong H, Liu S, Liu Y, Yin L, Tu C, Wang H, Zhao Z, Chen W, Mei Z
Frontiers in pharmacology 2019;10:354
Frontiers in pharmacology 2019;10:354
DDX23, an Evolutionary Conserved dsRNA Sensor, Participates in Innate Antiviral Responses by Pairing With TRIF or MAVS.
Ruan J, Cao Y, Ling T, Li P, Wu S, Peng D, Wang Y, Jia X, Chen S, Xu A, Yuan S
Frontiers in immunology 2019;10:2202
Frontiers in immunology 2019;10:2202
Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum.
Chen DQ, Cao G, Zhao H, Chen L, Yang T, Wang M, Vaziri ND, Guo Y, Zhao YY
Therapeutic advances in chronic disease 2019;10:2040622319869116
Therapeutic advances in chronic disease 2019;10:2040622319869116
Functional role of GKAP1 in the regulation of male germ cell spontaneous apoptosis and sperm number.
Wang H, Wang G, Dai Y, Li Z, Zhu Y, Sun F
Molecular reproduction and development 2019 Sep;86(9):1199-1209
Molecular reproduction and development 2019 Sep;86(9):1199-1209
miR-125b-5p targeting TRAF6 relieves skeletal muscle atrophy induced by fasting or denervation.
Qiu J, Zhu J, Zhang R, Liang W, Ma W, Zhang Q, Huang Z, Ding F, Sun H
Annals of translational medicine 2019 Sep;7(18):456
Annals of translational medicine 2019 Sep;7(18):456
Calcium channel blockers reduce severe fever with thrombocytopenia syndrome virus (SFTSV) related fatality.
Li H, Zhang LK, Li SF, Zhang SF, Wan WW, Zhang YL, Xin QL, Dai K, Hu YY, Wang ZB, Zhu XT, Fang YJ, Cui N, Zhang PH, Yuan C, Lu QB, Bai JY, Deng F, Xiao GF, Liu W, Peng K
Cell research 2019 Sep;29(9):739-753
Cell research 2019 Sep;29(9):739-753
Interaction of hnRNP K with MAP 1B-LC1 promotes TGF-β1-mediated epithelial to mesenchymal transition in lung cancer cells.
Li L, Yan S, Zhang H, Zhang M, Huang G, Chen M
BMC cancer 2019 Sep 6;19(1):894
BMC cancer 2019 Sep 6;19(1):894
Design, synthesis, antitumor activities and biological studies of novel diaryl substituted fused heterocycles as dual ligands targeting tubulin and katanin.
Gao F, Liang Y, Zhou P, Cheng J, Ding K, Wang Y
European journal of medicinal chemistry 2019 Sep 15;178:177-194
European journal of medicinal chemistry 2019 Sep 15;178:177-194
Proteomics Profiling of Host Cell Response via Protein Expression and Phosphorylation upon Dengue Virus Infection.
Miao M, Yu F, Wang D, Tong Y, Yang L, Xu J, Qiu Y, Zhou X, Zhao X
Virologica Sinica 2019 Oct;34(5):549-562
Virologica Sinica 2019 Oct;34(5):549-562
In situ repurposing of dendritic cells with CRISPR/Cas9-based nanomedicine to induce transplant tolerance.
Zhang Y, Shen S, Zhao G, Xu CF, Zhang HB, Luo YL, Cao ZT, Shi J, Zhao ZB, Lian ZX, Wang J
Biomaterials 2019 Oct;217:119302
Biomaterials 2019 Oct;217:119302
TGF‑β induces periodontal ligament stem cell senescence through increase of ROS production.
Fan C, Ji Q, Zhang C, Xu S, Sun H, Li Z
Molecular medicine reports 2019 Oct;20(4):3123-3130
Molecular medicine reports 2019 Oct;20(4):3123-3130
Crosstalk between Cdk5/p35 and ERK1/2 signalling mediates spinal astrocyte activity via the PPARγ pathway in a rat model of chronic constriction injury.
Zhong Y, Chen J, Chen J, Chen Y, Li L, Xie Y
Journal of neurochemistry 2019 Oct;151(2):166-184
Journal of neurochemistry 2019 Oct;151(2):166-184
CXCR7 regulates epileptic seizures by controlling the synaptic activity of hippocampal granule cells.
Xu T, Yu X, Deng J, Ou S, Liu X, Wang T, Liu Y, Yang J, Tan C, Yuan J, Chen Y
Cell death & disease 2019 Oct 31;10(11):825
Cell death & disease 2019 Oct 31;10(11):825
NEDD4 protects vascular endothelial cells against Angiotensin II-induced cell death via enhancement of XPO1-mediated nuclear export.
Xu J, Sheng Z, Li F, Wang S, Yuan Y, Wang M, Yu Z
Experimental cell research 2019 Oct 1;383(1):111505
Experimental cell research 2019 Oct 1;383(1):111505
The LIV-1-GRPEL1 axis adjusts cell fate during anti-mitotic agent-damaged mitosis.
Chen P, Wang B, Mo Q, Wu P, Fang Y, Tian Y, Jin X, Gao Y, Wu Y, Cao Y, Zhang Y, Xi L, Wang S, Hu J, Ma D, Zhou J, Gao Q, Chen G
EBioMedicine 2019 Nov;49:26-39
EBioMedicine 2019 Nov;49:26-39
Endoplasmic reticulum stress, a novel significant mechanism responsible for DEHP-induced increased distance between seminiferous tubule of mouse testis.
Pan J, Yao Y, Guo X, Kong F, Zhou J, Meng X
Journal of cellular physiology 2019 Nov;234(11):19807-19823
Journal of cellular physiology 2019 Nov;234(11):19807-19823
Deficiency of PTEN leads to aberrant chromosome segregation through downregulation of MAD2.
Sun Z, Lu J, Wu M, Li M, Bai L, Shi Z, Hao L, Wu Y
Molecular medicine reports 2019 Nov;20(5):4235-4243
Molecular medicine reports 2019 Nov;20(5):4235-4243
MicroRNA-125a-3p affects smooth muscle cell function in vascular stenosis.
Hu W, Chang G, Zhang M, Li Y, Yin L, Huang Y, Feng C, Gu Y, Wen D, Wang S
Journal of molecular and cellular cardiology 2019 Nov;136:85-94
Journal of molecular and cellular cardiology 2019 Nov;136:85-94
ASPP2 inhibits tumor growth by repressing the mevalonate pathway in hepatocellular carcinoma.
Liang B, Chen R, Song S, Wang H, Sun G, Yang H, Jing W, Zhou X, Fu Z, Huang G, Zhao J
Cell death & disease 2019 Nov 4;10(11):830
Cell death & disease 2019 Nov 4;10(11):830
Bioinformatics Analysis Identifies Protein Tyrosine Kinase 7 (PTK7) as a Potential Prognostic and Therapeutic Biomarker in Stages I to IV Hepatocellular Carcinoma.
Zou RC, Liang Y, Li LL, Tang JZ, Yang YP, Geng YC, He J, Luo LY, Li WX, Sun ZW, Yuan HL
Medical science monitor : international medical journal of experimental and clinical research 2019 Nov 15;25:8618-8627
Medical science monitor : international medical journal of experimental and clinical research 2019 Nov 15;25:8618-8627
Mitochondrial pyruvate carrier 2 mediates mitochondrial dysfunction and apoptosis in high glucose-treated podocytes.
Feng J, Ma Y, Chen Z, Hu J, Yang Q, Ding G
Life sciences 2019 Nov 15;237:116941
Life sciences 2019 Nov 15;237:116941
Enhancement of cortisol-induced SAA1 transcription by SAA1 in the human amnion.
Lu Y, Wang WS, Lin YK, Lu JW, Li WJ, Zhang CY, Sun K
Journal of molecular endocrinology 2019 May;62(4):149-158
Journal of molecular endocrinology 2019 May;62(4):149-158
Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial-lysosomal crosstalk.
Sheng J, Shen L, Sun L, Zhang X, Cui R, Wang L
Cell proliferation 2019 May;52(3):e12609
Cell proliferation 2019 May;52(3):e12609
Polypeptide N-acetylgalactosaminyltransferase 18 non-catalytically regulates the ER homeostasis and O-glycosylation.
Shan A, Lu J, Xu Z, Li X, Xu Y, Li W, Liu F, Yang F, Sato T, Narimatsu H, Zhang Y
Biochimica et biophysica acta. General subjects 2019 May;1863(5):870-882
Biochimica et biophysica acta. General subjects 2019 May;1863(5):870-882
Dorsomorphin induces cancer cell apoptosis and sensitizes cancer cells to HSP90 and proteasome inhibitors by reducing nuclear heat shock factor 1 levels.
Li N, Wang T, Li Z, Ye X, Deng B, Zhuo S, Yao P, Yang M, Mei H, Chen X, Zhu T, Chen S, Wang H, Wang J, Le Y
Cancer biology & medicine 2019 May;16(2):220-233
Cancer biology & medicine 2019 May;16(2):220-233
Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis.
Sabir N, Hussain T, Liao Y, Wang J, Song Y, Shahid M, Cheng G, Mangi MH, Yao J, Yang L, Zhao D, Zhou X
Cells 2019 May 5;8(5)
Cells 2019 May 5;8(5)
PTK2 promotes cancer stem cell traits in hepatocellular carcinoma by activating Wnt/β-catenin signaling.
Fan Z, Duan J, Wang L, Xiao S, Li L, Yan X, Yao W, Wu L, Zhang S, Zhang Y, Li Y, Zhu X, Hu Y, Zhang D, Jiao S, Xu X
Cancer letters 2019 May 28;450:132-143
Cancer letters 2019 May 28;450:132-143
Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation.
Zhang X, Ge Y, Bukhari AA, Zhu Q, Shen Y, Li M, Sun H, Su D, Liang X
Experimental & molecular medicine 2019 May 21;51(5):1-12
Experimental & molecular medicine 2019 May 21;51(5):1-12
Lamin A mutation impairs interaction with nucleoporin NUP155 and disrupts nucleocytoplasmic transport in atrial fibrillation.
Han M, Zhao M, Cheng C, Huang Y, Han S, Li W, Tu X, Luo X, Yu X, Liu Y, Chen Q, Ren X, Wang QK, Ke T
Human mutation 2019 Mar;40(3):310-325
Human mutation 2019 Mar;40(3):310-325
NFAT1 Hypermethylation Promotes Epithelial-Mesenchymal Transition and Metastasis in Nasopharyngeal Carcinoma by Activating ITGA6 Transcription.
Zhang J, Zheng ZQ, Yuan YW, Zhang PP, Li YQ, Wang YQ, Tang XR, Wen X, Hong XH, Lei Y, He QM, Yang XJ, Sun Y, Ma J, Liu N
Neoplasia (New York, N.Y.) 2019 Mar;21(3):311-321
Neoplasia (New York, N.Y.) 2019 Mar;21(3):311-321
UNBS5162 inhibits SKOV3 ovarian cancer cell proliferation by regulating the PI3K/AKT signalling pathway.
Wang Q, Shi W
Oncology letters 2019 Mar;17(3):2976-2982
Oncology letters 2019 Mar;17(3):2976-2982
CERKL regulates autophagy via the NAD-dependent deacetylase SIRT1.
Hu X, Lu Z, Yu S, Reilly J, Liu F, Jia D, Qin Y, Han S, Liu X, Qu Z, Lv Y, Li J, Huang Y, Jiang T, Jia H, Wang Q, Liu J, Shu X, Tang Z, Liu M
Autophagy 2019 Mar;15(3):453-465
Autophagy 2019 Mar;15(3):453-465
The selective HDAC6 inhibitor Nexturastat A induces apoptosis, overcomes drug resistance and inhibits tumor growth in multiple myeloma.
Sun X, Xie Y, Sun X, Yao Y, Li H, Li Z, Yao R, Xu K
Bioscience reports 2019 Mar 29;39(3)
Bioscience reports 2019 Mar 29;39(3)
Targeting the mDia Formin-Assembled Cytoskeleton Is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres.
Pettee KM, Becker KN, Alberts AS, Reinard KA, Schroeder JL, Eisenmann KM
Cancers 2019 Mar 20;11(3)
Cancers 2019 Mar 20;11(3)
An alternative membrane topology permits lipid droplet localization of peroxisomal fatty acyl-CoA reductase 1.
Exner T, Romero-Brey I, Yifrach E, Rivera-Monroy J, Schrul B, Zouboulis CC, Stremmel W, Honsho M, Bartenschlager R, Zalckvar E, Poppelreuther M, Füllekrug J
Journal of cell science 2019 Mar 18;132(6)
Journal of cell science 2019 Mar 18;132(6)
Accumulation of fructose 1,6-bisphosphate protects clear cell renal cell carcinoma from oxidative stress.
Wang J, Wu Q, Qiu J
Laboratory investigation; a journal of technical methods and pathology 2019 Jun;99(6):898-908
Laboratory investigation; a journal of technical methods and pathology 2019 Jun;99(6):898-908
Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production.
Mao Z, Lin H, Su W, Li J, Zhou M, Li Z, Zhou B, Yang Q, Zhou M, Pan K, He J, Zhang W
Diabetes 2019 Jun;68(6):1197-1209
Diabetes 2019 Jun;68(6):1197-1209
MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer.
He W, Liang B, Wang C, Li S, Zhao Y, Huang Q, Liu Z, Yao Z, Wu Q, Liao W, Zhang S, Liu Y, Xiang Y, Liu J, Shi M
Oncogene 2019 Jun;38(23):4637-4654
Oncogene 2019 Jun;38(23):4637-4654
Targeting Super-Enhancer-Driven Oncogenic Transcription by CDK7 Inhibition in Anaplastic Thyroid Carcinoma.
Cao X, Dang L, Zheng X, Lu Y, Lu Y, Ji R, Zhang T, Ruan X, Zhi J, Hou X, Yi X, Li MJ, Gu T, Gao M, Zhang L, Chen Y
Thyroid : official journal of the American Thyroid Association 2019 Jun;29(6):809-823
Thyroid : official journal of the American Thyroid Association 2019 Jun;29(6):809-823
MiR-15b-5p is Involved in Doxorubicin-Induced Cardiotoxicity via Inhibiting Bmpr1a Signal in H9c2 Cardiomyocyte.
Wan GX, Cheng L, Qin HL, Zhang YZ, Wang LY, Zhang YG
Cardiovascular toxicology 2019 Jun;19(3):264-275
Cardiovascular toxicology 2019 Jun;19(3):264-275
Antisense oligonucleotide treatment ameliorates IFN-γ-induced proteinuria in APOL1-transgenic mice.
Aghajan M, Booten SL, Althage M, Hart CE, Ericsson A, Maxvall I, Ochaba J, Menschik-Lundin A, Hartleib J, Kuntz S, Gattis D, Ahlström C, Watt AT, Engelhardt JA, Monia BP, Magnone MC, Guo S
JCI insight 2019 Jun 20;4(12)
JCI insight 2019 Jun 20;4(12)
The histone demethylase Kdm4 suppresses activation of hepatic stellate cell by inducing MiR-29 transcription.
Kong M, Wu J, Fan Z, Chen B, Wu T, Xu Y
Biochemical and biophysical research communications 2019 Jun 18;514(1):16-23
Biochemical and biophysical research communications 2019 Jun 18;514(1):16-23
Leonurine alleviates LPS-induced myocarditis through suppressing the NF-кB signaling pathway.
Wang R, Li D, Ouyang J, Tian X, Zhao Y, Peng X, Li S, Yu G, Yang J
Toxicology 2019 Jun 15;422:1-13
Toxicology 2019 Jun 15;422:1-13
Esrrb plays important roles in maintaining self-renewal of trophoblast stem cells (TSCs) and reprogramming somatic cells to induced TSCs.
Gao H, Gao R, Zhang L, Xiu W, Zang R, Wang H, Zhang Y, Chen J, Gao Y, Gao S
Journal of molecular cell biology 2019 Jun 1;11(6):463-473
Journal of molecular cell biology 2019 Jun 1;11(6):463-473
Dendrobium officinale polysaccharides regulate age-related lineage commitment between osteogenic and adipogenic differentiation.
Peng H, Yang M, Guo Q, Su T, Xiao Y, Xia ZY
Cell proliferation 2019 Jul;52(4):e12624
Cell proliferation 2019 Jul;52(4):e12624
Fine-Tuning of Shh/Gli Signaling Gradient by Non-proteolytic Ubiquitination during Neural Patterning.
Ma P, Song NN, Li Y, Zhang Q, Zhang L, Zhang L, Kong Q, Ma L, Yang X, Ren B, Li C, Zhao X, Li Y, Xu Y, Gao X, Ding YQ, Mao B
Cell reports 2019 Jul 9;28(2):541-553.e4
Cell reports 2019 Jul 9;28(2):541-553.e4
HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration.
Sun S, Cai B, Li Y, Su W, Zhao X, Gong B, Li Z, Zhang X, Wu Y, Chen C, Tsang SH, Yang J, Li X
Aging 2019 Jul 7;11(13):4323-4337
Aging 2019 Jul 7;11(13):4323-4337
NPRL2 enhances autophagy and the resistance to Everolimus in castration-resistant prostate cancer.
Chen Z, Jiang Q, Zhu P, Chen Y, Xie X, Du Z, Jiang L, Tang W
The Prostate 2019 Jan;79(1):44-53
The Prostate 2019 Jan;79(1):44-53
Isosteviol Sodium Protects Neural Cells Against Hypoxia-Induced Apoptosis Through Inhibiting MAPK and NF-κB Pathways.
Zhong KL, Lu MY, Liu F, Mei Y, Zhang XJ, Zhang H, Zan J, Sun XO, Tan W
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2019 Jan;28(1):175-184
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2019 Jan;28(1):175-184
FOXO1 associated with sensitivity to chemotherapy drugs and glial-mesenchymal transition in glioma.
Chen C, Han G, Li Y, Yue Z, Wang L, Liu J
Journal of cellular biochemistry 2019 Jan;120(1):882-893
Journal of cellular biochemistry 2019 Jan;120(1):882-893
The pivotal role of protein acetylation in linking glucose and fatty acid metabolism to β-cell function.
Zhang Y, Zhou F, Bai M, Liu Y, Zhang L, Zhu Q, Bi Y, Ning G, Zhou L, Wang X
Cell death & disease 2019 Jan 25;10(2):66
Cell death & disease 2019 Jan 25;10(2):66
HOXA9 is a novel myopia risk gene.
Liang CL, Hsu PY, Ngo CS, Seow WJ, Karnani N, Pan H, Saw SM, Juo SH
BMC ophthalmology 2019 Jan 23;19(1):28
BMC ophthalmology 2019 Jan 23;19(1):28
Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells.
Shi H, Wang XL, Quan HF, Yan L, Pei XY, Wang R, Peng XD
Molecules (Basel, Switzerland) 2019 Jan 21;24(2)
Molecules (Basel, Switzerland) 2019 Jan 21;24(2)
Targeting of LRRC59 to the Endoplasmic Reticulum and the Inner Nuclear Membrane.
Blenski M, Kehlenbach RH
International journal of molecular sciences 2019 Jan 15;20(2)
International journal of molecular sciences 2019 Jan 15;20(2)
Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
Han Y, Wu P, Wang Z, Zhang Z, Sun S, Liu J, Gong S, Gao P, Iwakuma T, Molina-Vila MA, Chen BP, Zhang Y, Ji T, Mo Q, Chen P, Hu J, Wang S, Zhou J, Lu H, Gao Q
EBioMedicine 2019 Feb;40:92-105
EBioMedicine 2019 Feb;40:92-105
An increase of estrogen receptor α protein level regulates BDE-209-mediated blood-testis barrier disruption during spermatogenesis in F1 mice.
Zhai J, Geng X, Ding T, Li J, Tang J, Chen D, Cui L, Wang Q
Environmental science and pollution research international 2019 Feb;26(5):4801-4820
Environmental science and pollution research international 2019 Feb;26(5):4801-4820
CD147 promotes progression of head and neck squamous cell carcinoma via NF-kappa B signaling.
Yu B, Zhang Y, Wu K, Wang L, Jiang Y, Chen W, Yan M
Journal of cellular and molecular medicine 2019 Feb;23(2):954-966
Journal of cellular and molecular medicine 2019 Feb;23(2):954-966
Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma.
Ma H, Yang W, Zhang L, Liu S, Zhao M, Zhou G, Wang L, Jin S, Zhang Z, Hu J
British journal of cancer 2019 Feb;120(3):317-330
British journal of cancer 2019 Feb;120(3):317-330
AMPK Promotes SPOP-Mediated NANOG Degradation to Regulate Prostate Cancer Cell Stemness.
Wang X, Jin J, Wan F, Zhao L, Chu H, Chen C, Liao G, Liu J, Yu Y, Teng H, Fang L, Jiang C, Pan W, Xie X, Li J, Lu X, Jiang X, Ge X, Ye D, Wang P
Developmental cell 2019 Feb 11;48(3):345-360.e7
Developmental cell 2019 Feb 11;48(3):345-360.e7
Helicobacter pylori induces intracellular galectin-8 aggregation around damaged lysosomes within gastric epithelial cells in a host O-glycan-dependent manner.
Li FY, Weng IC, Lin CH, Kao MC, Wu MS, Chen HY, Liu FT
Glycobiology 2019 Feb 1;29(2):151-162
Glycobiology 2019 Feb 1;29(2):151-162
Palmitoylome profiling indicates that androgens regulate the palmitoylation of α‑tubulin in prostate cancer‑derived LNCaP cells and supernatants.
Li W, Zhang J, Zou L, Cui J, Su F, Jin J, Xiao F, Liu M, Zhao G
Oncology reports 2019 Dec;42(6):2788-2796
Oncology reports 2019 Dec;42(6):2788-2796
Cancer‑associated adipocytes exhibit distinct phenotypes and facilitate tumor progression in pancreatic cancer.
Cai Z, Liang Y, Xing C, Wang H, Hu P, Li J, Huang H, Wang W, Jiang C
Oncology reports 2019 Dec;42(6):2537-2549
Oncology reports 2019 Dec;42(6):2537-2549
Adenosine Attenuates Aortic Smooth Muscle Cell Calcification through A(3) Adenosine Receptor.
Fujimoto K, Shioi A, Miki Y, Kakutani Y, Morioka T, Shoji T, Emoto M, Inaba M
The Tohoku journal of experimental medicine 2019 Dec;249(4):275-283
The Tohoku journal of experimental medicine 2019 Dec;249(4):275-283
Small GTPase Arf6 regulates diabetes-induced cholesterol accumulation in podocytes.
Hu J, Yang Q, Chen Z, Liang W, Feng J, Ding G
Journal of cellular physiology 2019 Dec;234(12):23559-23570
Journal of cellular physiology 2019 Dec;234(12):23559-23570
STRIP2 silencing inhibits vascular smooth muscle cell proliferation and migration via P38-AKT-MMP-2 signaling pathway.
Dai L, Zhou J, Li T, Qian Y, Jin L, Zhu C, Li S
Journal of cellular physiology 2019 Dec;234(12):22463-22476
Journal of cellular physiology 2019 Dec;234(12):22463-22476
Antitumor effects and mechanisms of 1,25(OH)2D3 in the Pfeiffer diffuse large B lymphoma cell line.
Han J, Tang Y, Zhong M, Wu W
Molecular medicine reports 2019 Dec;20(6):5064-5074
Molecular medicine reports 2019 Dec;20(6):5064-5074
A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum-associated degradation.
Shi J, Hu X, Guo Y, Wang L, Ji J, Li J, Zhang ZR
The Journal of biological chemistry 2019 Dec 27;294(52):20084-20096
The Journal of biological chemistry 2019 Dec 27;294(52):20084-20096
Membrane association but not identity is required for LRRK2 activation and phosphorylation of Rab GTPases.
Gomez RC, Wawro P, Lis P, Alessi DR, Pfeffer SR
The Journal of cell biology 2019 Dec 2;218(12):4157-4170
The Journal of cell biology 2019 Dec 2;218(12):4157-4170
Targeting CDK12-mediated transcription regulation in anaplastic thyroid carcinoma.
Geng M, Yang Y, Cao X, Dang L, Zhang T, Zhang L
Biochemical and biophysical research communications 2019 Dec 10;520(3):544-550
Biochemical and biophysical research communications 2019 Dec 10;520(3):544-550
Involvement of STAT3 in the synergistic induction of 11β-HSD1 by SAA1 and cortisol in human amnion fibroblasts.
Lu Y, Zhou Q, Lu JW, Wang WS, Sun K
American journal of reproductive immunology (New York, N.Y. : 1989) 2019 Aug;82(2):e13150
American journal of reproductive immunology (New York, N.Y. : 1989) 2019 Aug;82(2):e13150
Extracellular RNAs-TLR3 signaling contributes to cognitive decline in a mouse model of postoperative cognitive dysfunction.
Chen C, Gao R, Li M, Wang Q, Chen H, Zhang S, Mao X, Behensky A, Zhang Z, Gan L, Li T, Liao R, Li Q, Yu H, Yang J, Zhu T, Liu J
Brain, behavior, and immunity 2019 Aug;80:439-451
Brain, behavior, and immunity 2019 Aug;80:439-451
The Mechanism of Rap1 Regulates N-cadherin to Control Neuronal Migration.
Yang C, Li X, Zhang B, Fu S, Li S, Shen J, Guan L, Qiao L, Lin J
Journal of molecular neuroscience : MN 2019 Aug;68(4):539-548
Journal of molecular neuroscience : MN 2019 Aug;68(4):539-548
Total flavonoids from sea buckthorn ameliorates lipopolysaccharide/cigarette smoke-induced airway inflammation.
Ren QC, Li XH, Li QY, Yang HL, Wang HL, Zhang H, Zhao L, Jiang-Yong SL, Meng XL, Zhang Y, Shen XF
Phytotherapy research : PTR 2019 Aug;33(8):2102-2117
Phytotherapy research : PTR 2019 Aug;33(8):2102-2117
Initial human T-cell leukemia virus type 1 infection of the salivary gland epithelial cells requires a biofilm-like structure.
Nakamura H, Shimizu T, Takatani A, Suematsu T, Nakamura T, Kawakami A
Virus research 2019 Aug;269:197643
Virus research 2019 Aug;269:197643
E3 ligase Fbw7 participates in oxidative stress‑induced myocardial cell injury via interacting with Mcl‑1.
Li X, Zhang N, Zhang Y, Jia P, Guo Y, Tian Y, You S, Wu S, Sun Y
Molecular medicine reports 2019 Aug;20(2):1561-1568
Molecular medicine reports 2019 Aug;20(2):1561-1568
Inhibition of dendritic spine extension through acrolein conjugation with α-, β-tubulin proteins.
Uemura T, Suzuki T, Ko K, Watanabe K, Dohmae N, Sakamoto A, Terui Y, Toida T, Kashiwagi K, Igarashi K
The international journal of biochemistry & cell biology 2019 Aug;113:58-66
The international journal of biochemistry & cell biology 2019 Aug;113:58-66
Mitochondrial NOS1 suppresses apoptosis in colon cancer cells through increasing SIRT3 activity.
Wang Q, Ye S, Chen X, Xu P, Li K, Zeng S, Huang M, Gao W, Chen J, Zhang Q, Zhong Z, Liu Q
Biochemical and biophysical research communications 2019 Aug 6;515(4):517-523
Biochemical and biophysical research communications 2019 Aug 6;515(4):517-523
Krüppel-like factor 3 inhibition by mutated lncRNA Reg1cp results in human high bone mass syndrome.
Yang M, Guo Q, Peng H, Xiao YZ, Xiao Y, Huang Y, Li CJ, Su T, Zhang YL, Lei MX, Chen HL, Jiang TJ, Luo XH
The Journal of experimental medicine 2019 Aug 5;216(8):1944-1964
The Journal of experimental medicine 2019 Aug 5;216(8):1944-1964
Large-conductance calcium-activated potassium channels mediate lipopolysaccharide-induced activation of murine microglia.
Yang X, Wang G, Cao T, Zhang L, Ma Y, Jiang S, Teng X, Sun X
The Journal of biological chemistry 2019 Aug 30;294(35):12921-12932
The Journal of biological chemistry 2019 Aug 30;294(35):12921-12932
PAQR3 regulates phosphorylation of FoxO1 in insulin-resistant HepG2 cells via NF-κB signaling pathway.
Chen L, Sun X, Xiao H, Xu F, Yang Y, Lin Z, Chen Z, Quan S, Huang H
Experimental cell research 2019 Aug 15;381(2):301-310
Experimental cell research 2019 Aug 15;381(2):301-310
Inhibition of glycogen catabolism induces intrinsic apoptosis and augments multikinase inhibitors in hepatocellular carcinoma cells.
Barot S, Abo-Ali EM, Zhou DL, Palaguachi C, Dukhande VV
Experimental cell research 2019 Aug 15;381(2):288-300
Experimental cell research 2019 Aug 15;381(2):288-300
The Novel Nature Microtubule Inhibitor Ivalin Induces G2/M Arrest and Apoptosis in Human Hepatocellular Carcinoma SMMC-7721 Cells In Vitro.
Liu F, Lin S, Zhang C, Ma J, Han Z, Jia F, Xie W, Li X
Medicina (Kaunas, Lithuania) 2019 Aug 12;55(8)
Medicina (Kaunas, Lithuania) 2019 Aug 12;55(8)
SHIP1 inhibits cell growth, migration, and invasion in non‑small cell lung cancer through the PI3K/AKT pathway.
Fu Q, Huang Y, Ge C, Li Z, Tian H, Li Q, Li H, Li R, Tao X, Xue Y, Wang Y, Yang G, Fang W, Song X
Oncology reports 2019 Apr;41(4):2337-2350
Oncology reports 2019 Apr;41(4):2337-2350
Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation.
Ben J, Jiang B, Wang D, Liu Q, Zhang Y, Qi Y, Tong X, Chen L, Liu X, Zhang Y, Zhu X, Li X, Zhang H, Bai H, Yang Q, Ma J, Wiemer EAC, Xu Y, Chen Q
Nature communications 2019 Apr 17;10(1):1801
Nature communications 2019 Apr 17;10(1):1801
Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors.
Huang YY, Yu YF, Zhang C, Chen Y, Zhou Q, Li Z, Zhou S, Li Z, Guo L, Wu D, Wu Y, Luo HB
Journal of medicinal chemistry 2019 Apr 11;62(7):3707-3721
Journal of medicinal chemistry 2019 Apr 11;62(7):3707-3721
Altered expression of p63 isoforms and expansion of p63- and club cell secretory protein-positive epithelial cells in the lung as novel features of aging.
Fukumoto J, Sidramagowda Patil S, Krishnamurthy S, Saji S, John I, Narala VR, Hernández-Cuervo H, Alleyn M, Breitzig MT, Galam L, Soundararajan R, Chaudhari UK, Hansen BC, Lockey RF, Kolliputi N
American journal of physiology. Cell physiology 2019 Apr 1;316(4):C492-C508
American journal of physiology. Cell physiology 2019 Apr 1;316(4):C492-C508
Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.
Chen DQ, Cao G, Chen H, Argyopoulos CP, Yu H, Su W, Chen L, Samuels DC, Zhuang S, Bayliss GP, Zhao S, Yu XY, Vaziri ND, Wang M, Liu D, Mao JR, Ma SX, Zhao J, Zhang Y, Shang YQ, Kang H, Ye F, Cheng XH, Li XR, Zhang L, Meng MX, Guo Y, Zhao YY
Nature communications 2019 Apr 1;10(1):1476
Nature communications 2019 Apr 1;10(1):1476
Caspase-3 Inhibition Attenuates the Cytopathic Effects of EV71 Infection.
Song F, Yu X, Zhong T, Wang Z, Meng X, Li Z, Zhang S, Huo W, Liu X, Zhang Y, Zhang W, Yu J
Frontiers in microbiology 2018;9:817
Frontiers in microbiology 2018;9:817
The Protective Effect of Astaxanthin on Cognitive Function via Inhibition of Oxidative Stress and Inflammation in the Brains of Chronic T2DM Rats.
Feng Y, Chu A, Luo Q, Wu M, Shi X, Chen Y
Frontiers in pharmacology 2018;9:748
Frontiers in pharmacology 2018;9:748
Fas Signaling in Dendritic Cells Mediates Th2 Polarization in HDM-Induced Allergic Pulmonary Inflammation.
Han M, Hu R, Ma J, Zhang B, Chen C, Li H, Yang J, Huang G
Frontiers in immunology 2018;9:3045
Frontiers in immunology 2018;9:3045
TRIM31 Deficiency Is Associated with Impaired Glucose Metabolism and Disrupted Gut Microbiota in Mice.
Cheng J, Xue F, Zhang M, Cheng C, Qiao L, Ma J, Sui W, Xu X, Gao C, Hao P, Zhang M, Zhang Y
Frontiers in physiology 2018;9:24
Frontiers in physiology 2018;9:24
Klf4 Alleviates Lipopolysaccharide-Induced Inflammation by Inducing Expression of MCP-1 Induced Protein 1 to Deubiquitinate TRAF6.
Li Z, Jia Y, Han S, Wang X, Han F, Zhang J, Zhang W, Guan H, Hu D
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2278-2290
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2278-2290
Atorvastatin Attenuates Myocardial Hypertrophy in Spontaneously Hypertensive Rats via the C/EBPβ/PGC-1α/UCP3 Pathway.
Chen Y, Chang Y, Zhang N, Guo X, Sun G, Sun Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(3):1009-1018
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(3):1009-1018
Resveratrol-Induced Downregulation of NAF-1 Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine via the ROS/Nrf2 Signaling Pathways.
Cheng L, Yan B, Chen K, Jiang Z, Zhou C, Cao J, Qian W, Li J, Sun L, Ma J, Ma Q, Sha H
Oxidative medicine and cellular longevity 2018;2018:9482018
Oxidative medicine and cellular longevity 2018;2018:9482018
MiR-384 inhibits the proliferation of colorectal cancer by targeting AKT3.
Wang YX, Zhu HF, Zhang ZY, Ren F, Hu YH
Cancer cell international 2018;18:124
Cancer cell international 2018;18:124
XRCC1 rs1799782 (C194T) polymorphism correlated with tumor metastasis and molecular subtypes in breast cancer.
Li Q, Ma R, Zhang M
OncoTargets and therapy 2018;11:8435-8444
OncoTargets and therapy 2018;11:8435-8444
Liver-enriched activator protein 1 as an isoform of CCAAT/enhancer-binding protein beta suppresses stem cell features of hepatocellular carcinoma.
Yang LH, Wang Y, Qiao S, Wang MJ, Chen F, Zi XY, Li JX, Zhang HB, Yu B, Hu YP
Cancer management and research 2018;10:873-885
Cancer management and research 2018;10:873-885
The protective effects of distal ischemic treatment on apoptosis and mitochondrial permeability in the hippocampus after cardiopulmonary resuscitation.
Zhou X, Yong L, Huang Y, Zhu S, Song X, Li B, Zhu J, Wang H
Journal of cellular physiology 2018 Sep;233(9):6902-6910
Journal of cellular physiology 2018 Sep;233(9):6902-6910
The oncogenic potentials and diagnostic significance of long non-coding RNA LINC00310 in breast cancer.
Li J, Peng W, Du L, Yang Q, Wang C, Mo YY
Journal of cellular and molecular medicine 2018 Sep;22(9):4486-4495
Journal of cellular and molecular medicine 2018 Sep;22(9):4486-4495
Oocyte-specific deletion of G(s)α induces oxidative stress and deteriorates oocyte quality in mice.
Xie Y, Wu B, Jin Y, Zhang A, Sun X, Zhang X, Gao X, Dong R, Li H, Gao J
Experimental cell research 2018 Sep 15;370(2):579-590
Experimental cell research 2018 Sep 15;370(2):579-590
XPO1-mediated nuclear export of RNF146 protects from angiotensin II-induced endothelial cellular injury.
Sheng Z, Xu Y, Wang S, Yuan Y, Huang T, Lu P
Biochemical and biophysical research communications 2018 Sep 10;503(3):1544-1549
Biochemical and biophysical research communications 2018 Sep 10;503(3):1544-1549
Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction.
Ren Y, Chen J, Wu X, Gui C, Mao K, Zou F, Li W
Toxicological sciences : an official journal of the Society of Toxicology 2018 Sep 1;165(1):232-243
Toxicological sciences : an official journal of the Society of Toxicology 2018 Sep 1;165(1):232-243
MicroRNA-93 mediates cabergoline-resistance by targeting ATG7 in prolactinoma.
Wu Z, Cai L, Lu J, Wang C, Guan J, Chen X, Wu J, Zheng W, Wu Z, Li Q, Su Z
The Journal of endocrinology 2018 Sep 1;
The Journal of endocrinology 2018 Sep 1;
β-catenin regulates IRF3-mediated innate immune signalling in colorectal cancer.
Ding C, He J, Zhao J, Li J, Chen J, Liao W, Zeng Y, Zhong J, Wei C, Zhang L, Zhou M, Jia Z, Zhang Y, Li H, Zhou Y, Xiao X, Han D, Li C, Zhu Z, Xia Z, Peng J
Cell proliferation 2018 Oct;51(5):e12464
Cell proliferation 2018 Oct;51(5):e12464
Inhibitor of apoptosis protein‑like protein‑2: A novel growth accelerator for breast cancer cells.
Zhu L, Zhou W, Zhu X, Xiang S, Wang S, Peng Y, Lu B, Tang P, Chen Q, Wu M, Peng X, Chen Z, Sun Z, Yang K, Xiang M, Yu D
Oncology reports 2018 Oct;40(4):2047-2055
Oncology reports 2018 Oct;40(4):2047-2055
Low-density lipoprotein receptor-related protein 6 regulates alternative pre-mRNA splicing.
Yuan T, Wang S, Hu C, Wu Y, Liang D, Li L, Liu Y, Li J, Chen YH
Journal of cellular and molecular medicine 2018 Oct;22(10):4653-4663
Journal of cellular and molecular medicine 2018 Oct;22(10):4653-4663
Comparison of the Effects and Inhibitory Pathways of the Constituents from Gynostemma pentaphyllum against LPS-Induced Inflammatory Response.
Shen CY, Jiang JG, Shi MM, Yang HL, Wei H, Zhu W
Journal of agricultural and food chemistry 2018 Oct 31;66(43):11337-11346
Journal of agricultural and food chemistry 2018 Oct 31;66(43):11337-11346
Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7.
Yu B, Wu K, Wang X, Zhang J, Wang L, Jiang Y, Zhu X, Chen W, Yan M
Cell death & disease 2018 Oct 22;9(11):1082
Cell death & disease 2018 Oct 22;9(11):1082
Administration of ubiquitin-activating enzyme UBA1 inhibitor PYR-41 attenuates angiotensin II-induced cardiac remodeling in mice.
Shu Q, Lai S, Wang XM, Zhang YL, Yang XL, Bi HL, Li HH
Biochemical and biophysical research communications 2018 Oct 20;505(1):317-324
Biochemical and biophysical research communications 2018 Oct 20;505(1):317-324
ERα is a negative regulator of PD-L1 gene transcription in breast cancer.
Liu L, Shen Y, Zhu X, Lv R, Li S, Zhang Z, Shi YG, Tan L
Biochemical and biophysical research communications 2018 Oct 20;505(1):157-161
Biochemical and biophysical research communications 2018 Oct 20;505(1):157-161
Immune Activation of RAW264.7 Macrophages by Low Molecular Weight Fucoidan Extracted from New Zealand Undaria pinnatifida.
Bi D, Yu B, Han Q, Lu J, White WL, Lai Q, Cai N, Luo W, Gu L, Li S, Xu H, Hu Z, Nie S, Xu X
Journal of agricultural and food chemistry 2018 Oct 17;66(41):10721-10728
Journal of agricultural and food chemistry 2018 Oct 17;66(41):10721-10728
Nucleoporin35 is a novel microtubule associated protein functioning in oocyte meiotic spindle architecture.
Chen F, Jiao XF, Zhang JY, Wu D, Ding ZM, Wang YS, Miao YL, Huo LJ
Experimental cell research 2018 Oct 15;371(2):435-443
Experimental cell research 2018 Oct 15;371(2):435-443
Effects of Thymoquinone on radiation enteritis in mice.
Hou Q, Liu L, Dong Y, Wu J, Du L, Dong H, Li D
Scientific reports 2018 Oct 11;8(1):15122
Scientific reports 2018 Oct 11;8(1):15122
hnRNPK modulates selective quality-control autophagy by downregulating the expression of HDAC6 in 293 cells.
Li Z, Liu X, Ma J, Zhang T, Gao X, Liu L
International journal of oncology 2018 Nov;53(5):2200-2212
International journal of oncology 2018 Nov;53(5):2200-2212
Microtubule associated protein 4 phosphorylation leads to pathological cardiac remodeling in mice.
Li L, Zhang Q, Zhang X, Zhang J, Wang X, Ren J, Jia J, Zhang D, Jiang X, Zhang J, Mei H, Chen B, Hu J, Huang Y
EBioMedicine 2018 Nov;37:221-235
EBioMedicine 2018 Nov;37:221-235
Redox-active trace metal-induced release of high mobility group box 1(HMGB1) and inflammatory cytokines in fibroblast-like synovial cells is Toll-like receptor 4 (TLR4) dependent.
Alsousi AA, Igwe OJ
Biochimica et biophysica acta. Molecular basis of disease 2018 Nov;1864(11):3847-3858
Biochimica et biophysica acta. Molecular basis of disease 2018 Nov;1864(11):3847-3858
Activation of α7 nicotinic acetylcholine receptor alleviates Aβ(1-42)-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.
Chang KW, Zong HF, Ma KG, Zhai WY, Yang WN, Hu XD, Xu JH, Chen XL, Ji SF, Qian YH
Neurochemistry international 2018 Nov;120:238-250
Neurochemistry international 2018 Nov;120:238-250
TGF-β induces corneal endothelial senescence via increase of mitochondrial reactive oxygen species in chronic corneal allograft failure.
Li Z, Liu T, Ma J, Guo Q, Ma L, Lv Q, Jiang Y, Wei C, Zhang J
Aging 2018 Nov 28;10(11):3474-3485
Aging 2018 Nov 28;10(11):3474-3485
Annexin A5 regulates hepatocarcinoma malignancy via CRKI/II-DOCK180-RAC1 integrin and MEK-ERK pathways.
Sun X, Liu S, Wang J, Wei B, Guo C, Chen C, Sun MZ
Cell death & disease 2018 May 25;9(6):637
Cell death & disease 2018 May 25;9(6):637
HSF4 transcriptional regulates HMOX-1 expression in HLECs.
Liao S, Qu Z, Li L, Zhou B, Gao M, Huang M, Li D
Gene 2018 May 20;655:30-34
Gene 2018 May 20;655:30-34
Targeting LC3 and Beclin-1 autophagy genes suppresses proliferation, survival, migration and invasion by inhibition of Cyclin-D1 and uPAR/Integrin β1/ Src signaling in triple negative breast cancer cells.
Hamurcu Z, Delibaşı N, Geçene S, Şener EF, Dönmez-Altuntaş H, Özkul Y, Canatan H, Ozpolat B
Journal of cancer research and clinical oncology 2018 Mar;144(3):415-430
Journal of cancer research and clinical oncology 2018 Mar;144(3):415-430
Elucidation of the Molecular-Mechanisms and In Vivo Evaluation of the Anti-inflammatory Effect of Alginate-Derived Seleno-polymannuronate.
Bi D, Lai Q, Cai N, Li T, Zhang Y, Han Q, Peng Y, Xu H, Lu J, Bao W, Liu Q, Xu X
Journal of agricultural and food chemistry 2018 Mar 7;66(9):2083-2091
Journal of agricultural and food chemistry 2018 Mar 7;66(9):2083-2091
Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity.
Tata PR, Chow RD, Saladi SV, Tata A, Konkimalla A, Bara A, Montoro D, Hariri LP, Shih AR, Mino-Kenudson M, Mou H, Kimura S, Ellisen LW, Rajagopal J
Developmental cell 2018 Mar 26;44(6):679-693.e5
Developmental cell 2018 Mar 26;44(6):679-693.e5
Transcriptional Regulation of the Warburg Effect in Cancer by SIX1.
Li L, Liang Y, Kang L, Liu Y, Gao S, Chen S, Li Y, You W, Dong Q, Hong T, Yan Z, Jin S, Wang T, Zhao W, Mai H, Huang J, Han X, Ji Q, Song Q, Yang C, Zhao S, Xu X, Ye Q
Cancer cell 2018 Mar 12;33(3):368-385.e7
Cancer cell 2018 Mar 12;33(3):368-385.e7
Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1.
Jin S, Ma H, Yang W, Ju H, Wang L, Zhang Z
Journal of molecular medicine (Berlin, Germany) 2018 Jun;96(6):513-525
Journal of molecular medicine (Berlin, Germany) 2018 Jun;96(6):513-525
High expression of NPRL2 is linked to poor prognosis in patients with prostate cancer.
Chen Z, Luo S, Chen Y, Xie X, Du Z, Jiang L
Human pathology 2018 Jun;76:141-148
Human pathology 2018 Jun;76:141-148
An adenosine A1R-A2aR imbalance regulates low glucose/hypoxia-induced microglial activation, thereby contributing to oligodendrocyte damage through NF-κB and CREB phosphorylation.
Huang W, Bai S, Zuo X, Tang W, Chen P, Chen X, Wang G, Wang H, Xie P
International journal of molecular medicine 2018 Jun;41(6):3559-3569
International journal of molecular medicine 2018 Jun;41(6):3559-3569
Sofosbuvir inhibits hepatitis A virus replication in vitro assessed by a cell-based fluorescent reporter system.
Jiang W, Muhammad F, Ma P, Liu X, Long G
Antiviral research 2018 Jun;154:51-57
Antiviral research 2018 Jun;154:51-57
CD300A promotes tumor progression by PECAM1, ADCY7 and AKT pathway in acute myeloid leukemia.
Sun X, Huang S, Wang X, Zhang X, Wang X
Oncotarget 2018 Jun 8;9(44):27574-27584
Oncotarget 2018 Jun 8;9(44):27574-27584
HuR regulates telomerase activity through TERC methylation.
Tang H, Wang H, Cheng X, Fan X, Yang F, Zhang M, Chen Y, Tian Y, Liu C, Shao D, Jiang B, Dou Y, Cong Y, Xing J, Zhang X, Yi X, Songyang Z, Ma W, Zhao Y, Wang X, Ma J, Gorospe M, Ju Z, Wang W
Nature communications 2018 Jun 7;9(1):2213
Nature communications 2018 Jun 7;9(1):2213
Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice.
Crotty Alexander LE, Drummond CA, Hepokoski M, Mathew D, Moshensky A, Willeford A, Das S, Singh P, Yong Z, Lee JH, Vega K, Du A, Shin J, Javier C, Tian J, Brown JH, Breen EC
American journal of physiology. Regulatory, integrative and comparative physiology 2018 Jun 1;314(6):R834-R847
American journal of physiology. Regulatory, integrative and comparative physiology 2018 Jun 1;314(6):R834-R847
Ubiquitin-specific protease 11 serves as a marker of poor prognosis and promotes metastasis in hepatocellular carcinoma.
Zhang S, Xie C, Li H, Zhang K, Li J, Wang X, Yin Z
Laboratory investigation; a journal of technical methods and pathology 2018 Jul;98(7):883-894
Laboratory investigation; a journal of technical methods and pathology 2018 Jul;98(7):883-894
Basolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress.
Lu M, Wu J, Hao ZW, Shang YK, Xu J, Nan G, Li X, Chen ZN, Bian H
Hepatology (Baltimore, Md.) 2018 Jul;68(1):317-332
Hepatology (Baltimore, Md.) 2018 Jul;68(1):317-332
Novel inhibitors of the cellular renin-angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/β-catenin pathway against renal fibrosis.
Wang M, Chen DQ, Chen L, Cao G, Zhao H, Liu D, Vaziri ND, Guo Y, Zhao YY
British journal of pharmacology 2018 Jul;175(13):2689-2708
British journal of pharmacology 2018 Jul;175(13):2689-2708
Epigenetic activation of PERP transcription by MKL1 contributes to ROS-induced apoptosis in skeletal muscle cells.
Li Z, Chen B, Dong W, Xu W, Song M, Fang M, Guo J, Xu Y
Biochimica et biophysica acta. Gene regulatory mechanisms 2018 Jul 27;
Biochimica et biophysica acta. Gene regulatory mechanisms 2018 Jul 27;
Taurocholic acid is an active promoting factor, not just a biomarker of progression of liver cirrhosis: evidence from a human metabolomic study and in vitro experiments.
Liu Z, Zhang Z, Huang M, Sun X, Liu B, Guo Q, Chang Q, Duan Z
BMC gastroenterology 2018 Jul 11;18(1):112
BMC gastroenterology 2018 Jul 11;18(1):112
Cisplatin and curcumin co-loaded nano-liposomes for the treatment of hepatocellular carcinoma.
Cheng Y, Zhao P, Wu S, Yang T, Chen Y, Zhang X, He C, Zheng C, Li K, Ma X, Xiang G
International journal of pharmaceutics 2018 Jul 10;545(1-2):261-273
International journal of pharmaceutics 2018 Jul 10;545(1-2):261-273
Human Cytomegalovirus Protein pUL38 Prevents Premature Cell Death by Binding to Ubiquitin-Specific Protease 24 and Regulating Iron Metabolism.
Sun Y, Bao Q, Xuan B, Xu W, Pan D, Li Q, Qian Z
Journal of virology 2018 Jul 1;92(13)
Journal of virology 2018 Jul 1;92(13)
Aberrant hypermethylation of the HOXD10 gene in papillary thyroid cancer with BRAFV600E mutation.
Cao YM, Gu J, Zhang YS, Wei WJ, Qu N, Wen D, Liao T, Shi RL, Zhang L, Ji QH, Wang Y, Sun GH, Zhao YX, Wang YJ, Yu J, Zhu YX
Oncology reports 2018 Jan;39(1):338-348
Oncology reports 2018 Jan;39(1):338-348
Exogenous oxidants activate nuclear factor kappa B through Toll-like receptor 4 stimulation to maintain inflammatory phenotype in macrophage.
Zhang Y, Igwe OJ
Biochemical pharmacology 2018 Jan;147:104-118
Biochemical pharmacology 2018 Jan;147:104-118
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y
European journal of medicinal chemistry 2018 Jan 20;144:817-842
European journal of medicinal chemistry 2018 Jan 20;144:817-842
Ubiquitin-Specific Protease USP6 Regulates the Stability of the c-Jun Protein.
Li L, Yang H, He Y, Li T, Feng J, Chen W, Ao L, Shi X, Lin Y, Liu H, Zheng E, Lin Q, Bu J, Zeng Y, Zheng M, Xu Y, Liao Z, Lin J, Lin D
Molecular and cellular biology 2018 Jan 15;38(2)
Molecular and cellular biology 2018 Jan 15;38(2)
Novel RAS Inhibitors Poricoic Acid ZG and Poricoic Acid ZH Attenuate Renal Fibrosis via a Wnt/β-Catenin Pathway and Targeted Phosphorylation of smad3 Signaling.
Wang M, Chen DQ, Chen L, Liu D, Zhao H, Zhang ZH, Vaziri ND, Guo Y, Zhao YY, Cao G
Journal of agricultural and food chemistry 2018 Feb 28;66(8):1828-1842
Journal of agricultural and food chemistry 2018 Feb 28;66(8):1828-1842
Interferon-alpha enhances the antitumour activity of EGFR-targeted therapies by upregulating RIG-I in head and neck squamous cell carcinoma.
Ma H, Jin S, Yang W, Zhou G, Zhao M, Fang S, Zhang Z, Hu J
British journal of cancer 2018 Feb 20;118(4):509-521
British journal of cancer 2018 Feb 20;118(4):509-521
Carvedilol attenuates liver fibrosis by suppressing autophagy and promoting apoptosis in hepatic stellate cells.
Meng D, Li Z, Wang G, Ling L, Wu Y, Zhang C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1617-1627
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1617-1627
Dynasore-induced potent ubiquitylation of the exon 19 deletion mutant of epidermal growth factor receptor suppresses cell growth and migration in non-small cell lung cancer.
Wang T, Wang D, Zhang Y, Zhang J, Sun X, Wu Y, Wang S, Zhang Y, Xu L, Kong Q, Gao Y, Wu Y, Liu F, Liu S, Zhang Y, Lei T, Liu H
The international journal of biochemistry & cell biology 2018 Dec;105:1-12
The international journal of biochemistry & cell biology 2018 Dec;105:1-12
Hypothalamic DNA methylation in rats with dihydrotestosterone-induced polycystic ovary syndrome: effects of low-frequency electro-acupuncture.
Cui P, Ma T, Tamadon A, Han S, Li B, Chen Z, An X, Shao LR, Wang Y, Feng Y
Experimental physiology 2018 Dec;103(12):1618-1632
Experimental physiology 2018 Dec;103(12):1618-1632
TUSC3 accelerates cancer growth and induces epithelial-mesenchymal transition by upregulating claudin-1 in non-small-cell lung cancer cells.
Feng S, Zhai J, Lu D, Lin J, Dong X, Liu X, Wu H, Roden AC, Brandi G, Tavolari S, Bille A, Cai K
Experimental cell research 2018 Dec 15;373(1-2):44-56
Experimental cell research 2018 Dec 15;373(1-2):44-56
Fucoidan Alleviates Acetaminophen-Induced Hepatotoxicity via Oxidative Stress Inhibition and Nrf2 Translocation.
Wang YQ, Wei JG, Tu MJ, Gu JG, Zhang W
International journal of molecular sciences 2018 Dec 14;19(12)
International journal of molecular sciences 2018 Dec 14;19(12)
Aging-dependent decrease in the numbers of enteric neurons, interstitial cells of Cajal and expression of connexin43 in various regions of gastrointestinal tract.
Sun T, Li D, Hu S, Huang L, Sun H, Yang S, Wu B, Ji F, Zhou D
Aging 2018 Dec 11;10(12):3851-3865
Aging 2018 Dec 11;10(12):3851-3865
Expression profiling identified IL-8 as a regulator of homotypic cell-in-cell formation.
Ruan B, Wang C, Chen A, Liang J, Niu Z, Zheng Y, Fan J, Gao L, Huang H, Wang X, Sun Q
BMB reports 2018 Aug;51(8):412-417
BMB reports 2018 Aug;51(8):412-417
Suppressed epithelial-mesenchymal transition and cancer stem cell properties mediate the anti-cancer effects of ethyl pyruvate via regulation of the AKT/nuclear factor-κB pathway in prostate cancer cells.
Huang B, Lv DJ, Wang C, Shu FP, Gong ZC, Xie T, Yu YZ, Song XL, Xie JJ, Li S, Liu YM, Qi H, Zhao SC
Oncology letters 2018 Aug;16(2):2271-2278
Oncology letters 2018 Aug;16(2):2271-2278
Selenium-enriched yeast inhibited β-amyloid production and modulated autophagy in a triple transgenic mouse model of Alzheimer's disease.
Song GL, Chen C, Wu QY, Zhang ZH, Zheng R, Chen Y, Jia SZ, Ni JZ
Metallomics : integrated biometal science 2018 Aug 15;10(8):1107-1115
Metallomics : integrated biometal science 2018 Aug 15;10(8):1107-1115
SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice.
Qin K, Zhang N, Zhang Z, Nipper M, Zhu Z, Leighton J, Xu K, Musi N, Wang P
Diabetologia 2018 Apr;61(4):906-918
Diabetologia 2018 Apr;61(4):906-918
Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.
Pao KC, Wood NT, Knebel A, Rafie K, Stanley M, Mabbitt PD, Sundaramoorthy R, Hofmann K, van Aalten DMF, Virdee S
Nature 2018 Apr;556(7701):381-385
Nature 2018 Apr;556(7701):381-385
Histone Methyltransferase SETDB1 Promotes the Progression of Colorectal Cancer by Inhibiting the Expression of TP53.
Chen K, Zhang F, Ding J, Liang Y, Zhan Z, Zhan Y, Chen LH, Ding Y
Journal of Cancer 2017;8(16):3318-3330
Journal of Cancer 2017;8(16):3318-3330
Rabies Virus Infection Induces Microtubule Depolymerization to Facilitate Viral RNA Synthesis by Upregulating HDAC6.
Zan J, Liu S, Sun DN, Mo KK, Yan Y, Liu J, Hu BL, Gu JY, Liao M, Zhou JY
Frontiers in cellular and infection microbiology 2017;7:146
Frontiers in cellular and infection microbiology 2017;7:146
Hydrogen sulfide generation from l-cysteine in the human glioblastoma-astrocytoma U-87 MG and neuroblastoma SHSY5Y cell lines.
Bronowicka-Adamska P, Bentke A, Wróbel M
Acta biochimica Polonica 2017;64(1):171-176
Acta biochimica Polonica 2017;64(1):171-176
HMGB1 binding heptamer peptide improves survival and ameliorates brain injury in rats after cardiac arrest and cardiopulmonary resuscitation.
Shi X, Li M, Huang K, Zhou S, Hu Y, Pan S, Gu Y
Neuroscience 2017 Sep 30;360:128-138
Neuroscience 2017 Sep 30;360:128-138
FAM83D, a microtubule-associated protein, promotes tumor growth and progression of human gastric cancer.
Huang M, Ma X, Shi H, Hu L, Fan Z, Pang L, Zhu F, Yang X, Xu W, Liu B, Zhu Z, Li C
Oncotarget 2017 Sep 26;8(43):74479-74493
Oncotarget 2017 Sep 26;8(43):74479-74493
2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G(2)/M cell cycle arrest through generation of thiol oxidative stress in human esophageal cancer cells.
Li X, Jiang Z, Feng J, Zhang X, Wu J, Chen W
Oncotarget 2017 Sep 22;8(37):61846-61860
Oncotarget 2017 Sep 22;8(37):61846-61860
Palladin is a novel microtubule-associated protein responsible for spindle orientation.
Zhang X, Chen X, Liu J, Xu X, Zhang Y, Ruan Z, Xie Y, Huang Q, Yin T, Chen Z, Chen S
Scientific reports 2017 Sep 18;7(1):11806
Scientific reports 2017 Sep 18;7(1):11806
Antisense Oligonucleotide-Mediated Removal of the Polyglutamine Repeat in Spinocerebellar Ataxia Type 3 Mice.
Toonen LJA, Rigo F, van Attikum H, van Roon-Mom WMC
Molecular therapy. Nucleic acids 2017 Sep 15;8:232-242
Molecular therapy. Nucleic acids 2017 Sep 15;8:232-242
PKC θ-mediated Ca(2+)/NF-AT signalling pathway may be involved in T-cell immunosuppression in coal-burning arsenic-poisoned population.
Zeng Q, Luo P, Gu J, Liang B, Liu Q, Zhang A
Environmental toxicology and pharmacology 2017 Oct;55:44-50
Environmental toxicology and pharmacology 2017 Oct;55:44-50
Neuroprotective Effects of Lycium barbarum Polysaccharide on Focal Cerebral Ischemic Injury in Mice.
Zhao P, Zhou R, Zhu XY, Liu G, Zhao YP, Ma PS, Wu W, Niu Y, Sun T, Li YX, Yu JQ, Qian ZM
Neurochemical research 2017 Oct;42(10):2798-2813
Neurochemical research 2017 Oct;42(10):2798-2813
NOR1 Suppresses Cancer Stem-Like Cells Properties of Tumor Cells via the Inhibition of the AKT-GSK-3β-Wnt/β-catenin-ALDH1A1 Signal Circuit.
Wang W, Yi M, Chen S, Li J, Zhang H, Xiong W, Li G, Li X, Xiang B
Journal of cellular physiology 2017 Oct;232(10):2829-2840
Journal of cellular physiology 2017 Oct;232(10):2829-2840
HIF-1α coordinates epigenetic activation of SIAH1 in hepatocytes in response to nutritional stress.
Fan Z, Li Z, Yang Y, Liu S, Guo J, Xu Y
Biochimica et biophysica acta. Gene regulatory mechanisms 2017 Oct;1860(10):1037-1046
Biochimica et biophysica acta. Gene regulatory mechanisms 2017 Oct;1860(10):1037-1046
Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O(6)-methylguanine-DNA methyltransferase.
Chang KY, Hsu TI, Hsu CC, Tsai SY, Liu JJ, Chou SW, Liu MS, Liou JP, Ko CY, Chen KY, Hung JJ, Chang WC, Chuang CK, Kao TJ, Chuang JY
Redox biology 2017 Oct;13:655-664
Redox biology 2017 Oct;13:655-664
Inhibition of IL-8-mediated endothelial adhesion, VSMCs proliferation and migration by siRNA-TMEM98 suggests TMEM98's emerging role in atherosclerosis.
Lv G, Zhu H, Li C, Wang J, Zhao D, Li S, Ma L, Sun G, Li F, Zhao Y, Gao Y
Oncotarget 2017 Oct 20;8(50):88043-88058
Oncotarget 2017 Oct 20;8(50):88043-88058
Regulation of m(6)A Transcripts by the 3'→5' RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline.
Wojtas MN, Pandey RR, Mendel M, Homolka D, Sachidanandam R, Pillai RS
Molecular cell 2017 Oct 19;68(2):374-387.e12
Molecular cell 2017 Oct 19;68(2):374-387.e12
Downregulation of NAD-Dependent Deacetylase SIRT2 Protects Mouse Brain Against Ischemic Stroke.
Xie XQ, Zhang P, Tian B, Chen XQ
Molecular neurobiology 2017 Nov;54(9):7251-7261
Molecular neurobiology 2017 Nov;54(9):7251-7261
Analysis of gene expression and functional characterization of XPR1: a pathogenic gene for primary familial brain calcification.
Yao XP, Zhao M, Wang C, Guo XX, Su HZ, Dong EL, Chen HT, Lai JH, Liu YB, Wang N, Chen WJ
Cell and tissue research 2017 Nov;370(2):267-273
Cell and tissue research 2017 Nov;370(2):267-273
BRAFV600E and RET/PTC Promote Proliferation and Migration of Papillary Thyroid Carcinoma Cells In Vitro by Regulating Nuclear Factor-κB.
Zhou D, Li Z, Bai X
Medical science monitor : international medical journal of experimental and clinical research 2017 Nov 8;23:5321-5329
Medical science monitor : international medical journal of experimental and clinical research 2017 Nov 8;23:5321-5329
Stress stimuli induce cancer-stemness gene expression via Sp1 activation leading to therapeutic resistance in glioblastoma.
Chang KY, Huang CT, Hsu TI, Hsu CC, Liu JJ, Chuang CK, Hung JJ, Chang WC, Tsai KK, Chuang JY
Biochemical and biophysical research communications 2017 Nov 4;493(1):14-19
Biochemical and biophysical research communications 2017 Nov 4;493(1):14-19
Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency.
Lorenzo DN, Bennett V
Proceedings of the National Academy of Sciences of the United States of America 2017 Nov 28;114(48):12743-12748
Proceedings of the National Academy of Sciences of the United States of America 2017 Nov 28;114(48):12743-12748
PADI2-Mediated Citrullination Promotes Prostate Cancer Progression.
Wang L, Song G, Zhang X, Feng T, Pan J, Chen W, Yang M, Bai X, Pang Y, Yu J, Han J, Han B
Cancer research 2017 Nov 1;77(21):5755-5768
Cancer research 2017 Nov 1;77(21):5755-5768
Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer.
Zhang X, Fu L, Xue D, Zhang X, Hao F, Xie L, He J, Gai J, Liu Y, Xu H, Li Q, Wang E
Virchows Archiv : an international journal of pathology 2017 May;470(5):553-560
Virchows Archiv : an international journal of pathology 2017 May;470(5):553-560
A critical role of Hrd1 in the regulation of optineurin degradation and aggresome formation.
Mao J, Xia Q, Liu C, Ying Z, Wang H, Wang G
Human molecular genetics 2017 May 15;26(10):1877-1889
Human molecular genetics 2017 May 15;26(10):1877-1889
MicroRNA let-7g possesses a therapeutic potential for peripheral artery disease.
Hsu PY, Hsi E, Wang TM, Lin RT, Liao YC, Juo SH
Journal of cellular and molecular medicine 2017 Mar;21(3):519-529
Journal of cellular and molecular medicine 2017 Mar;21(3):519-529
PTPIP51 regulates mouse cardiac ischemia/reperfusion through mediating the mitochondria-SR junction.
Qiao X, Jia S, Ye J, Fang X, Zhang C, Cao Y, Xu C, Zhao L, Zhu Y, Wang L, Zheng M
Scientific reports 2017 Mar 27;7:45379
Scientific reports 2017 Mar 27;7:45379
Protein synthesis inhibition and GADD34 control IFN-β heterogeneous expression in response to dsRNA.
Dalet A, Argüello RJ, Combes A, Spinelli L, Jaeger S, Fallet M, Vu Manh TP, Mendes A, Perego J, Reverendo M, Camosseto V, Dalod M, Weil T, Santos MA, Gatti E, Pierre P
The EMBO journal 2017 Mar 15;36(6):761-782
The EMBO journal 2017 Mar 15;36(6):761-782
Overexpression of WDFY2 inhibits prostate cancer cell growth and migration via inactivation of Akt pathway.
Wang J, Chen X, Tong S, Zhou H, Sun J, Gou Y, Wu F, Hu J, Xu J, Ding G
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jun;39(6):1010428317704821
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jun;39(6):1010428317704821
JOSD1 Negatively Regulates Type-I Interferon Antiviral Activity by Deubiquitinating and Stabilizing SOCS1.
Wang X, Zhang L, Zhang Y, Zhao P, Qian L, Yuan Y, Liu J, Cheng Q, Xu W, Zuo Y, Guo T, Yu Z, Zheng H
Viral immunology 2017 Jun;30(5):342-349
Viral immunology 2017 Jun;30(5):342-349
Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming.
Sun S, Liu J, Zhao M, Han Y, Chen P, Mo Q, Wang B, Chen G, Fang Y, Tian Y, Zhou J, Ma D, Gao Q, Wu P
Cell death & disease 2017 Jun 8;8(6):e2870
Cell death & disease 2017 Jun 8;8(6):e2870
Long noncoding RNA CRNDE stabilized by hnRNPUL2 accelerates cell proliferation and migration in colorectal carcinoma via activating Ras/MAPK signaling pathways.
Jiang H, Wang Y, Ai M, Wang H, Duan Z, Wang H, Zhao L, Yu J, Ding Y, Wang S
Cell death & disease 2017 Jun 8;8(6):e2862
Cell death & disease 2017 Jun 8;8(6):e2862
Long-Term Dietary Supplementation with Selenium-Enriched Yeast Improves Cognitive Impairment, Reverses Synaptic Deficits, and Mitigates Tau Pathology in a Triple Transgenic Mouse Model of Alzheimer's Disease.
Zhang ZH, Wen L, Wu QY, Chen C, Zheng R, Liu Q, Ni JZ, Song GL
Journal of agricultural and food chemistry 2017 Jun 21;65(24):4970-4979
Journal of agricultural and food chemistry 2017 Jun 21;65(24):4970-4979
Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats.
Huijuan W, Xiaoxu C, Rui S, Xinghui L, Beibei T, Jianchun M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:358-365
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:358-365
Knockdown of homeobox containing 1 increases the radiosensitivity of cervical cancer cells through telomere shortening.
Zhou S, Xiao Y, Zhuang Y, Liu Y, Zhao H, Yang H, Xie C, Zhou F, Zhou Y
Oncology reports 2017 Jul;38(1):515-521
Oncology reports 2017 Jul;38(1):515-521
Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via exosomes.
Zhang J, Lu S, Zhou Y, Meng K, Chen Z, Cui Y, Shi Y, Wang T, He QY
Proteomics 2017 Jul;17(13-14)
Proteomics 2017 Jul;17(13-14)
BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells.
Zhang X, Jiang S, Mitok KA, Li L, Attie AD, Martin TFJ
The Journal of cell biology 2017 Jul 3;216(7):2151-2166
The Journal of cell biology 2017 Jul 3;216(7):2151-2166
Anthocyanins from Black Chokeberry (Aroniamelanocarpa Elliot) Delayed Aging-Related Degenerative Changes of Brain.
Wei J, Zhang G, Zhang X, Xu D, Gao J, Fan J, Zhou Z
Journal of agricultural and food chemistry 2017 Jul 26;65(29):5973-5984
Journal of agricultural and food chemistry 2017 Jul 26;65(29):5973-5984
Thymoquinone Attenuates Brain Injury via an Anti-oxidative Pathway in a Status Epilepticus Rat Model.
Shao YY, Li B, Huang YM, Luo Q, Xie YM, Chen YH
Translational neuroscience 2017 Jan;8:9-14
Translational neuroscience 2017 Jan;8:9-14
A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity.
Xu X, Fan Z, Liang C, Li L, Wang L, Liang Y, Wu J, Chang S, Yan Z, Lv Z, Fu J, Liu Y, Jin S, Wang T, Hong T, Dong Y, Ding L, Cheng L, Liu R, Fu S, Jiao S, Ye Q
Nature communications 2017 Jan 17;8:14059
Nature communications 2017 Jan 17;8:14059
Functional analysis reveals that RBM10 mutations contribute to lung adenocarcinoma pathogenesis by deregulating splicing.
Zhao J, Sun Y, Huang Y, Song F, Huang Z, Bao Y, Zuo J, Saffen D, Shao Z, Liu W, Wang Y
Scientific reports 2017 Jan 16;7:40488
Scientific reports 2017 Jan 16;7:40488
Characteristics of Chinese herbal medicine usage in ischemic heart disease patients among type 2 diabetes and their protection against hydrogen peroxide-mediated apoptosis in H9C2 cardiomyoblasts.
Tsai FJ, Ho TJ, Cheng CF, Shiao YT, Chien WK, Chen JH, Liu X, Tsang H, Lin TH, Liao CC, Huang SM, Li JP, Lin CW, Lin JG, Lan YC, Liu YH, Hung CH, Lin JC, Lin CC, Lai CH, Liang WM, Lin YJ
Oncotarget 2017 Feb 28;8(9):15470-15489
Oncotarget 2017 Feb 28;8(9):15470-15489
Anthocyanins Delay Ageing-Related Degenerative Changes in the Liver.
Wei J, Zhang G, Zhang X, Xu D, Gao J, Fan J
Plant foods for human nutrition (Dordrecht, Netherlands) 2017 Dec;72(4):425-431
Plant foods for human nutrition (Dordrecht, Netherlands) 2017 Dec;72(4):425-431
Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models.
Yu M, Fu Y, Liang Y, Song H, Yao Y, Wu P, Yao Y, Pan Y, Wen X, Ma L, Hexige S, Ding Y, Luo S, Lu B
Cell research 2017 Dec;27(12):1441-1465
Cell research 2017 Dec;27(12):1441-1465
miR-34b Modulates Skeletal Muscle Cell Proliferation and Differentiation.
Tang Z, Qiu H, Luo L, Liu N, Zhong J, Kang K, Gou D
Journal of cellular biochemistry 2017 Dec;118(12):4285-4295
Journal of cellular biochemistry 2017 Dec;118(12):4285-4295
HRD1 prevents apoptosis in renal tubular epithelial cells by mediating eIF2α ubiquitylation and degradation.
Huang Y, Sun Y, Cao Y, Sun H, Li M, You H, Su D, Li Y, Liang X
Cell death & disease 2017 Dec 11;8(12):3202
Cell death & disease 2017 Dec 11;8(12):3202
Autoregulation of RBM10 and cross-regulation of RBM10/RBM5 via alternative splicing-coupled nonsense-mediated decay.
Sun Y, Bao Y, Han W, Song F, Shen X, Zhao J, Zuo J, Saffen D, Chen W, Wang Z, You X, Wang Y
Nucleic acids research 2017 Aug 21;45(14):8524-8540
Nucleic acids research 2017 Aug 21;45(14):8524-8540
MiR-30c regulates cisplatin-induced apoptosis of renal tubular epithelial cells by targeting Bnip3L and Hspa5.
Du B, Dai XM, Li S, Qi GL, Cao GX, Zhong Y, Yin PD, Yang XS
Cell death & disease 2017 Aug 10;8(8):e2987
Cell death & disease 2017 Aug 10;8(8):e2987
Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.
Chen L, Chen DQ, Wang M, Liu D, Chen H, Dou F, Vaziri ND, Zhao YY
Chemico-biological interactions 2017 Aug 1;273:56-72
Chemico-biological interactions 2017 Aug 1;273:56-72
Non-hemolytic enterotoxin of Bacillus cereus induces apoptosis in Vero cells.
Liu X, Ding S, Shi P, Dietrich R, Märtlbauer E, Zhu K
Cellular microbiology 2017 Apr;19(4)
Cellular microbiology 2017 Apr;19(4)
Adipose-derived mesenchymal stem cells promote osteosarcoma proliferation and metastasis by activating the STAT3 pathway.
Wang Y, Chu Y, Yue B, Ma X, Zhang G, Xiang H, Liu Y, Wang T, Wu X, Chen B
Oncotarget 2017 Apr 4;8(14):23803-23816
Oncotarget 2017 Apr 4;8(14):23803-23816
MiR-466b-1-3p regulates P-glycoprotein expression in rat cerebral microvascular endothelial cells.
Yang X, Ren W, Shao Y, Chen Y
Neuroscience letters 2017 Apr 3;645:60-66
Neuroscience letters 2017 Apr 3;645:60-66
Vav1 expression is increased in esophageal squamous cell carcinoma and indicates poor prognosis.
Zhu X, Jin H, Xia Z, Wu X, Yang M, Zhang H, Shang X, Cheng R, Zhan Z, Yu Z
Biochemical and biophysical research communications 2017 Apr 29;486(2):571-576
Biochemical and biophysical research communications 2017 Apr 29;486(2):571-576
Atorvastatin prevents Angiotensin II induced myocardial hypertrophy in vitro via CCAAT/enhancer-binding protein β.
Chen Y, Yu S, Zhang N, Li Y, Chen S, Chang Y, Sun G, Sun Y
Biochemical and biophysical research communications 2017 Apr 29;486(2):423-430
Biochemical and biophysical research communications 2017 Apr 29;486(2):423-430
Satb2 Ablation Impairs Hippocampus-Based Long-Term Spatial Memory and Short-Term Working Memory and Immediate Early Genes (IEGs)-Mediated Hippocampal Synaptic Plasticity.
Li Y, You QL, Zhang SR, Huang WY, Zou WJ, Jie W, Li SJ, Liu JH, Lv CY, Cong J, Hu YY, Gao TM, Li JM
Molecular neurobiology 2017 Apr 18;
Molecular neurobiology 2017 Apr 18;
High-dose irradiation in combination with toll-like receptor 9 agonist CpG oligodeoxynucleotide 7909 downregulates PD-L1 expression via the NF-κB signaling pathway in non-small cell lung cancer cells.
Chen X, Zhang Q, Luo Y, Gao C, Zhuang X, Xu G, Qiao T
OncoTargets and therapy 2016;9:6511-6518
OncoTargets and therapy 2016;9:6511-6518
Achaete-Scute Homolog 1 Expression Controls Cellular Differentiation of Neuroblastoma.
Kasim M, Heß V, Scholz H, Persson PB, Fähling M
Frontiers in molecular neuroscience 2016;9:156
Frontiers in molecular neuroscience 2016;9:156
Sulforaphane induces apoptosis and inhibits invasion in U251MG glioblastoma cells.
Zhang Z, Li C, Shang L, Zhang Y, Zou R, Zhan Y, Bi B
SpringerPlus 2016;5:235
SpringerPlus 2016;5:235
Premutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding.
Napoli E, Ross-Inta C, Song G, Wong S, Hagerman R, Gane LW, Smilowitz JT, Tassone F, Giulivi C
Frontiers in neuroscience 2016;10:159
Frontiers in neuroscience 2016;10:159
Rabies virus inactivates cofilin to facilitate viral budding and release.
Zan J, An ST, Mo KK, Zhou JW, Liu J, Wang HL, Yan Y, Liao M, Zhou JY
Biochemical and biophysical research communications 2016 Sep 2;477(4):1045-1050
Biochemical and biophysical research communications 2016 Sep 2;477(4):1045-1050
Toll-like receptor 2-mediated MAPKs and NF-κB activation requires the GNAO1-dependent pathway in human mast cells.
Jin M, Yu B, Zhang W, Zhang W, Xiao Z, Mao Z, Lai Y, Lin D, Ma Q, Pan E, Zhang Y, Yu Y
Integrative biology : quantitative biosciences from nano to macro 2016 Sep 12;8(9):968-75
Integrative biology : quantitative biosciences from nano to macro 2016 Sep 12;8(9):968-75
MicroRNA-106a regulates phosphatase and tensin homologue expression and promotes the proliferation and invasion of ovarian cancer cells.
Chen L, Zhang F, Sheng XG, Zhang SQ, Chen YT, Liu BW
Oncology reports 2016 Oct;36(4):2135-41
Oncology reports 2016 Oct;36(4):2135-41
NLRP3 inflammasome mediates contrast media-induced acute kidney injury by regulating cell apoptosis.
Shen J, Wang L, Jiang N, Mou S, Zhang M, Gu L, Shao X, Wang Q, Qi C, Li S, Wang W, Che X, Ni Z
Scientific reports 2016 Oct 10;6:34682
Scientific reports 2016 Oct 10;6:34682
Tetraiodothyroacetic acid and transthyretin silencing inhibit pro-metastatic effect of L-thyroxin in anoikis-resistant prostate cancer cells through regulation of MAPK/ERK pathway.
Zhang P, Chen L, Song Y, Li X, Sun Y, Xiao Y, Xing Y
Experimental cell research 2016 Oct 1;347(2):350-9
Experimental cell research 2016 Oct 1;347(2):350-9
Niacin receptor GPR109A inhibits insulin secretion and is down-regulated in type 2 diabetic islet beta-cells.
Wang N, Guo DY, Tian X, Lin HP, Li YP, Chen SJ, Fu YC, Xu WC, Wei CJ
General and comparative endocrinology 2016 Oct 1;237:98-108
General and comparative endocrinology 2016 Oct 1;237:98-108
Polypeptide N-Acetylgalactosaminyltransferase 13 Contributes to Neurogenesis via Stabilizing the Mucin-type O-Glycoprotein Podoplanin.
Xu Y, Pang W, Lu J, Shan A, Zhang Y
The Journal of biological chemistry 2016 Nov 4;291(45):23477-23488
The Journal of biological chemistry 2016 Nov 4;291(45):23477-23488
Characterization of Brain-Penetrant Pyrimidine-Containing Molecules with Differential Microtubule-Stabilizing Activities Developed as Potential Therapeutic Agents for Alzheimer's Disease and Related Tauopathies.
Kovalevich J, Cornec AS, Yao Y, James M, Crowe A, Lee VM, Trojanowski JQ, Smith AB 3rd, Ballatore C, Brunden KR
The Journal of pharmacology and experimental therapeutics 2016 May;357(2):432-50
The Journal of pharmacology and experimental therapeutics 2016 May;357(2):432-50
CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway.
Wen Q, Wang W, Luo J, Chu S, Chen L, Xu L, Zang H, Alnemah MM, Ma J, Fan S
Oncotarget 2016 May 10;7(19):27787-801
Oncotarget 2016 May 10;7(19):27787-801
Pdcd4 restrains the self-renewal and white-to-beige transdifferentiation of adipose-derived stem cells.
Bai Y, Shang Q, Zhao H, Pan Z, Guo C, Zhang L, Wang Q
Cell death & disease 2016 Mar 31;7(3):e2169
Cell death & disease 2016 Mar 31;7(3):e2169
Cell Autonomous and Nonautonomous Function of CUL4B in Mouse Spermatogenesis.
Yin Y, Liu L, Yang C, Lin C, Veith GM, Wang C, Sutovsky P, Zhou P, Ma L
The Journal of biological chemistry 2016 Mar 25;291(13):6923-35
The Journal of biological chemistry 2016 Mar 25;291(13):6923-35
Renalase attenuates hypertension, renal injury and cardiac remodelling in rats with subtotal nephrectomy.
Yin J, Lu Z, Wang F, Jiang Z, Lu L, Miao N, Wang N
Journal of cellular and molecular medicine 2016 Jun;20(6):1106-17
Journal of cellular and molecular medicine 2016 Jun;20(6):1106-17
Go is required for the release of IL-8 and TNF-α, but not degranulation in human mast cells.
Yu Y, Huang Z, Mao Z, Zhang Y, Jin M, Chen W, Zhang W, Yu B, Zhang W, Alaster Lau HY
European journal of pharmacology 2016 Jun 5;780:115-21
European journal of pharmacology 2016 Jun 5;780:115-21
Deletion of Brg1 causes abnormal hair cell planer polarity, hair cell anchorage, and scar formation in mouse cochlea.
Jin Y, Ren N, Li S, Fu X, Sun X, Men Y, Xu Z, Zhang J, Xie Y, Xia M, Gao J
Scientific reports 2016 Jun 3;6:27124
Scientific reports 2016 Jun 3;6:27124
miR-1301 promotes prostate cancer proliferation through directly targeting PPP2R2C.
Bi D, Ning H, Liu S, Que X, Ding K
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Jul;81:25-30
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Jul;81:25-30
MiR-130a regulates neurite outgrowth and dendritic spine density by targeting MeCP2.
Zhang Y, Chen M, Qiu Z, Hu K, McGee W, Chen X, Liu J, Zhu L, Wu JY
Protein & cell 2016 Jul;7(7):489-500
Protein & cell 2016 Jul;7(7):489-500
Inhibition of histone deacetylases induces formation of multipolar spindles and subsequent p53-dependent apoptosis in nasopharyngeal carcinoma cells.
Yan M, Qian YM, Yue CF, Wang ZF, Wang BC, Zhang W, Zheng FM, Liu Q
Oncotarget 2016 Jul 12;7(28):44171-44184
Oncotarget 2016 Jul 12;7(28):44171-44184
PfIRR Interacts with HrIGF-I and Activates the MAP-kinase and PI3-kinase Signaling Pathways to Regulate Glycogen Metabolism in Pinctada fucata.
Shi Y, He MX
Scientific reports 2016 Feb 25;6:22063
Scientific reports 2016 Feb 25;6:22063
Nogo-B receptor promotes the chemoresistance of human hepatocellular carcinoma via the ubiquitination of p53 protein.
Dong C, Zhao B, Long F, Liu Y, Liu Z, Li S, Yang X, Sun D, Wang H, Liu Q, Liang R, Li Y, Gao Z, Shao S, Miao QR, Wang L
Oncotarget 2016 Feb 23;7(8):8850-65
Oncotarget 2016 Feb 23;7(8):8850-65
Spatially coordinated dynamic gene transcription in living pituitary tissue.
Featherstone K, Hey K, Momiji H, McNamara AV, Patist AL, Woodburn J, Spiller DG, Christian HC, McNeilly AS, Mullins JJ, Finkenstädt BF, Rand DA, White MR, Davis JR
eLife 2016 Feb 1;5:e08494
eLife 2016 Feb 1;5:e08494
Anxa5 mediates the in vitro malignant behaviours of murine hepatocarcinoma Hca-F cells with high lymph node metastasis potential preferentially via ERK2/p-ERK2/c-Jun/p-c-Jun(Ser73) and E-cadherin.
Sun X, Wei B, Liu S, Guo C, Wu N, Liu Q, Sun MZ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:645-654
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:645-654
Protective Effects of Thymoquinone Against Convulsant Activity Induced by Lithium-Pilocarpine in a model of Status Epilepticus.
Shao Y, Feng Y, Xie Y, Luo Q, Chen L, Li B, Chen Y
Neurochemical research 2016 Dec;41(12):3399-3406
Neurochemical research 2016 Dec;41(12):3399-3406
Etomidate inhibits nuclear factor-κB through decreased expression of glucocorticoid receptor in septic rats.
Zhang Y, Li RM, Wang C, Liu N, Lv S, Xiong JY
Molecular medicine reports 2016 Dec;14(6):5760-5766
Molecular medicine reports 2016 Dec;14(6):5760-5766
SUMOylated MAFB promotes colorectal cancer tumorigenesis.
Yang LS, Zhang XJ, Xie YY, Sun XJ, Zhao R, Huang QH
Oncotarget 2016 Dec 13;7(50):83488-83501
Oncotarget 2016 Dec 13;7(50):83488-83501
Gp130-mediated STAT3 activation by S-propargyl-cysteine, an endogenous hydrogen sulfide initiator, prevents doxorubicin-induced cardiotoxicity.
Wu J, Guo W, Lin SZ, Wang ZJ, Kan JT, Chen SY, Zhu YZ
Cell death & disease 2016 Aug 18;7(8):e2339
Cell death & disease 2016 Aug 18;7(8):e2339
The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.
Liu X, Chen L, Ge J, Yan C, Huang Z, Hu J, Wen C, Li M, Huang D, Qiu Y, Hao H, Yuan R, Lei J, Yu X, Shao J
Cancer research 2016 Aug 15;76(16):4897-907
Cancer research 2016 Aug 15;76(16):4897-907
miR-935 promotes gastric cancer cell proliferation by targeting SOX7.
Yang M, Cui G, Ding M, Yang W, Liu Y, Dai D, Chen L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Apr;79:153-8
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Apr;79:153-8
Loss-of-function Mutation in PMVK Causes Autosomal Dominant Disseminated Superficial Porokeratosis.
Wang J, Liu Y, Liu F, Huang C, Han S, Lv Y, Liu CJ, Zhang S, Qin Y, Ling L, Gao M, Yu S, Li C, Huang M, Liao S, Hu X, Lu Z, Liu X, Jiang T, Tang Z, Zhang H, Guo AY, Liu M
Scientific reports 2016 Apr 7;6:24226
Scientific reports 2016 Apr 7;6:24226
ZBTB20 is required for anterior pituitary development and lactotrope specification.
Cao D, Ma X, Cai J, Luan J, Liu AJ, Yang R, Cao Y, Zhu X, Zhang H, Chen YX, Shi Y, Shi GX, Zou D, Cao X, Grusby MJ, Xie Z, Zhang WJ
Nature communications 2016 Apr 15;7:11121
Nature communications 2016 Apr 15;7:11121
Pigment Epithelium-Derived Factor Induces Endothelial Barrier Dysfunction via p38/MAPK Phosphorylation.
He T, Zhao L, Zhang D, Zhang Q, Jia J, Hu J, Huang Y
BioMed research international 2015;2015:791825
BioMed research international 2015;2015:791825
Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells.
Zhao X, Fang Y, Yang Y, Qin Y, Wu P, Wang T, Lai H, Meng L, Wang D, Zheng Z, Lu X, Zhang H, Gao Q, Zhou J, Ma D
Autophagy 2015;11(10):1849-63
Autophagy 2015;11(10):1849-63
High expression of transforming acidic coiled coil-containing protein 3 strongly correlates with aggressive characteristics and poor prognosis of gastric cancer.
Yun M, Rong J, Lin ZR, He YL, Zhang JX, Peng ZW, Tang LQ, Zeng MS, Zhong Q, Ye S
Oncology reports 2015 Sep;34(3):1397-405
Oncology reports 2015 Sep;34(3):1397-405
Adipose-derived mesenchymal stem cells promote cell proliferation and invasion of epithelial ovarian cancer.
Chu Y, Tang H, Guo Y, Guo J, Huang B, Fang F, Cai J, Wang Z
Experimental cell research 2015 Sep 10;337(1):16-27
Experimental cell research 2015 Sep 10;337(1):16-27
The role of autophagy in the cytotoxicity induced by recombinant human arginase in laryngeal squamous cell carcinoma.
Lin C, Wang Z, Li L, He Y, Fan J, Liu Z, Zhao S, Ju D
Applied microbiology and biotechnology 2015 Oct;99(20):8487-94
Applied microbiology and biotechnology 2015 Oct;99(20):8487-94
Real Time Monitoring of Inhibition of Adipogenesis and Angiogenesis by (-)-Epigallocatechin-3-Gallate in 3T3-L1 Adipocytes and Human Umbilical Vein Endothelial Cells.
Tang W, Song H, Cai W, Shen X
Nutrients 2015 Oct 27;7(10):8871-86
Nutrients 2015 Oct 27;7(10):8871-86
P38/MAPK contributes to endothelial barrier dysfunction via MAP4 phosphorylation-dependent microtubule disassembly in inflammation-induced acute lung injury.
Li L, Hu J, He T, Zhang Q, Yang X, Lan X, Zhang D, Mei H, Chen B, Huang Y
Scientific reports 2015 Mar 9;5:8895
Scientific reports 2015 Mar 9;5:8895
Proteomic characterization of the nucleolar linker histone H1 interaction network.
Szerlong HJ, Herman JA, Krause CM, DeLuca JG, Skoultchi A, Winger QA, Prenni JE, Hansen JC
Journal of molecular biology 2015 Jun 5;427(11):2056-71
Journal of molecular biology 2015 Jun 5;427(11):2056-71
Hypoxia inducible factor-1 mediates expression of miR-322: potential role in proliferation and migration of pulmonary arterial smooth muscle cells.
Zeng Y, Liu H, Kang K, Wang Z, Hui G, Zhang X, Zhong J, Peng W, Ramchandran R, Raj JU, Gou D
Scientific reports 2015 Jul 13;5:12098
Scientific reports 2015 Jul 13;5:12098
Bipartite Nuclear Localization Signal Controls Nuclear Import and DNA-Binding Activity of IFN Regulatory Factor 3.
Zhu M, Fang T, Li S, Meng K, Guo D
Journal of immunology (Baltimore, Md. : 1950) 2015 Jul 1;195(1):289-97
Journal of immunology (Baltimore, Md. : 1950) 2015 Jul 1;195(1):289-97
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Aras S, Bai M, Lee I, Springett R, Hüttemann M, Grossman LI
Mitochondrion 2015 Jan;20:43-51
Mitochondrion 2015 Jan;20:43-51
Shear-sensitive microRNA-34a modulates flow-dependent regulation of endothelial inflammation.
Fan W, Fang R, Wu X, Liu J, Feng M, Dai G, Chen G, Wu G
Journal of cell science 2015 Jan 1;128(1):70-80
Journal of cell science 2015 Jan 1;128(1):70-80
Cytoplasmic hnRNPK interacts with GSK3β and is essential for the osteoclast differentiation.
Fan X, Xiong H, Wei J, Gao X, Feng Y, Liu X, Zhang G, He QY, Xu J, Liu L
Scientific reports 2015 Dec 7;5:17732
Scientific reports 2015 Dec 7;5:17732
IFN-γ-mediated IRF1/miR-29b feedback loop suppresses colorectal cancer cell growth and metastasis by repressing IGF1.
Yuan L, Zhou C, Lu Y, Hong M, Zhang Z, Zhang Z, Chang Y, Zhang C, Li X
Cancer letters 2015 Apr 1;359(1):136-47
Cancer letters 2015 Apr 1;359(1):136-47
Importin 7 and Nup358 promote nuclear import of the protein component of human telomerase.
Frohnert C, Hutten S, Wälde S, Nath A, Kehlenbach RH
PloS one 2014;9(2):e88887
PloS one 2014;9(2):e88887
Naringin inhibits TNF-α induced oxidative stress and inflammatory response in HUVECs via Nox4/NF-κ B and PI3K/Akt pathways.
Li W, Wang C, Peng J, Liang J, Jin Y, Liu Q, Meng Q, Liu K, Sun H
Current pharmaceutical biotechnology 2014;15(12):1173-82
Current pharmaceutical biotechnology 2014;15(12):1173-82
Novel approaches for the identification of nuclear transport receptor substrates.
Kimura M, Thakar K, Karaca S, Imamoto N, Kehlenbach RH
Methods in cell biology 2014;122:353-78
Methods in cell biology 2014;122:353-78
Insulin-like growth factor binding protein 4 enhances cardiomyocytes induction in murine-induced pluripotent stem cells.
Xue Y, Yan Y, Gong H, Fang B, Zhou Y, Ding Z, Yin P, Zhang G, Ye Y, Yang C, Ge J, Zou Y
Journal of cellular biochemistry 2014 Sep;115(9):1495-504
Journal of cellular biochemistry 2014 Sep;115(9):1495-504
Probing the cell death signaling pathway of HepG2 cell line induced by copper-1,10-phenanthroline complex.
Wu J, Chen W, Yin Y, Zheng Z, Zou G
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2014 Jun;27(3):445-58
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2014 Jun;27(3):445-58
The role of autophagy in the neurotoxicity of cationic PAMAM dendrimers.
Wang S, Li Y, Fan J, Wang Z, Zeng X, Sun Y, Song P, Ju D
Biomaterials 2014 Aug;35(26):7588-97
Biomaterials 2014 Aug;35(26):7588-97
Chromatin-remodeling factors mediate the balance of sense-antisense transcription at the FGF2 locus.
McEachern LA, Murphy PR
Molecular endocrinology (Baltimore, Md.) 2014 Apr;28(4):477-89
Molecular endocrinology (Baltimore, Md.) 2014 Apr;28(4):477-89
Pin1 promotes GR transactivation by enhancing recruitment to target genes.
Poolman TM, Farrow SN, Matthews L, Loudon AS, Ray DW
Nucleic acids research 2013 Oct;41(18):8515-25
Nucleic acids research 2013 Oct;41(18):8515-25
Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry.
Thakar K, Karaca S, Port SA, Urlaub H, Kehlenbach RH
Molecular & cellular proteomics : MCP 2013 Mar;12(3):664-78
Molecular & cellular proteomics : MCP 2013 Mar;12(3):664-78
Several phenylalanine-glycine motives in the nucleoporin Nup214 are essential for binding of the nuclear export receptor CRM1.
Roloff S, Spillner C, Kehlenbach RH
The Journal of biological chemistry 2013 Feb 8;288(6):3952-63
The Journal of biological chemistry 2013 Feb 8;288(6):3952-63
Resolution doubling in fluorescence microscopy with confocal spinning-disk image scanning microscopy.
Schulz O, Pieper C, Clever M, Pfaff J, Ruhlandt A, Kehlenbach RH, Wouters FS, Großhans J, Bunt G, Enderlein J
Proceedings of the National Academy of Sciences of the United States of America 2013 Dec 24;110(52):21000-5
Proceedings of the National Academy of Sciences of the United States of America 2013 Dec 24;110(52):21000-5
Long-distance intercellular connectivity between cardiomyocytes and cardiofibroblasts mediated by membrane nanotubes.
He K, Shi X, Zhang X, Dang S, Ma X, Liu F, Xu M, Lv Z, Han D, Fang X, Zhang Y
Cardiovascular research 2011 Oct 1;92(1):39-47
Cardiovascular research 2011 Oct 1;92(1):39-47
Intercellular transportation of quantum dots mediated by membrane nanotubes.
He K, Luo W, Zhang Y, Liu F, Liu D, Xu L, Qin L, Xiong C, Lu Z, Fang X, Zhang Y
ACS nano 2010 Jun 22;4(6):3015-22
ACS nano 2010 Jun 22;4(6):3015-22
Regulation of FGF-2 by an endogenous antisense RNA: effects on cell adhesion and cell-cycle progression.
MacFarlane LA, Murphy PR
Molecular carcinogenesis 2010 Dec;49(12):1031-44
Molecular carcinogenesis 2010 Dec;49(12):1031-44
Regulation of fibroblast growth factor-2 by an endogenous antisense RNA and by argonaute-2.
MacFarlane LA, Gu Y, Casson AG, Murphy PR
Molecular endocrinology (Baltimore, Md.) 2010 Apr;24(4):800-12
Molecular endocrinology (Baltimore, Md.) 2010 Apr;24(4):800-12
CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells.
Li GD, Zhang X, Li R, Wang YD, Wang YL, Han KJ, Qian XP, Yang CG, Liu P, Wei Q, Chen WF, Zhang J, Zhang Y
The Journal of biological chemistry 2008 Nov 21;283(47):32660-8
The Journal of biological chemistry 2008 Nov 21;283(47):32660-8
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- Western blot of Hela cell with anti-Tubulin-Alpha (11224-1-AP) at various dilutions.
- Sample type
- cell line
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- Proteintech Group (provider)
- Main image
- Experimental details
- The alpha Tubulin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human alpha Tubulin. This antibody recognizes human,mouse,rat antigen. The alpha Tubulin antibody has been validated for the following applications: ELISA, WB, IP, IHC, IF analysis.
Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells using 11224-1-AP( Tubulin-Alpha Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
- Sample type
- cell line
Supportive validation
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- Proteintech Group (provider)
- Main image
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- IP Result of anti-Tubulin-Alpha (IP:11224-1-AP, 3ug; Detection:11224-1-AP 1:1000) with HeLa cells lysate 5000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 11224-1-AP(Tubulin-Alpha antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 11224-1-AP(Tubulin-Alpha antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
