Antibody data

Product number
11-12008 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-MEIS1 Antibody
Antibody type
Polyclonal
Description
Myeloid ecotropoic viral insertion site 1 (MEIS1) is a transcription factor belonging to TALE (three amino acids loop extension) family. The gene for MEIS1 is mapped to human chromosome 2p15. The amino terminus contains binding domains for its interaction partners, the transcription factors HOXA9 and PBX1, followed by a homeobox DNA binding domain and carboxy-terminal transcriptional activation domains. It is expressed in hematopoietic stem and progenitor cells and increases during human megakaryocytic differentiation. MEIS1 plays a role in the normal development of the hematopoietic lineage and is over expressed in a subset of acute myeloid leukemias. Increased MEIS1 expression has also been observed in neuroblastomas and the expression level of the MEIS1 transcript is a prognostic indicator in breast cancer.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant MEIS1
protein (amino acids 163-352) was u
sed as the immunogen for this antib
ody.
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
MEIS1 protein structure - 11-12008 shown in red.