Antibody data
- Antibody Data
- Antigen structure
- References [57]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 10970-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10970-1-AP, RRID:AB_10596918
- Product name
- PABPC1,PABP antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PABPC1,PABP antibody (Cat. #10970-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The atypical E3 ligase HOIL-1 safeguards the ribosome during cellular stress.
circPLEKHM1 promotes tumor growth and metastasis through enhancing FXR1-mediated protein translation in PDAC.
TAG-PL: A Universal Proximity Labeling Platform for Mapping Mitochondrial Proteomes and Organelle Interactions under Stress.
A Circular RNA Promotes Tumor Metastasis through Stabilizing MSI2 Protein in Pancreatic Ductal Adenocarcinoma.
TOB Proteins Repress Translation via the CCR4-NOT Deadenylase Complex Independent of Deadenylation.
Targeting PABPC1: A therapeutic strategy of natural Ganoderma meroterpenoid LZ22 against triple-negative breast cancer proliferation.
CRTC2 Forms Co-Condensates with YTHDF2 That Enhance Translational Efficiency of m6A-Modified mRNAs to Drive Hepatocarcinogenesis and Lenvatinib Resistance.
The RNA-stability-independent role of the RNA m(6)A reader YTHDF2 in promoting protein translation to confer tumor chemotherapy resistance.
A circular RNA overcomes acquired resistance to BET inhibitors by antagonizing IGF2BP2-mediated c-MYC translation in TNBC.
Engineering bi-directional chemically-modulated synthetic condensates for cellular control.
TRIM38 Inhibits Zika Virus by Upregulating RIG-I/MDA5 Pathway and Promoting Ubiquitin-Mediated Degradation of Viral NS3 Protein.
LINC00882, transcriptionally activated by CEBP-β and post-transcriptionally stabilized by METTL14-mediated m(6)A modification, exerts tumorigenesis by promoting PABPC1-mediated stabilization of ELK3 mRNA.
Eukaryotic translation elongation factor 1 alpha 1 facilitates coxsackievirus B replication through interacting with PABP, viral protein 3 CD and viral RNA.
Ribosome biogenesis as a potential therapeutic target in KRAS mutant colorectal cancer.
Transferrin receptor 1 (TfR1) functions as an entry receptor for scale drop disease virus to invade the host cell via clathrin-mediated endocytosis.
Inhibition of GRK2 reduced doxorubicin-induced oxidative stress and apoptosis through upregulating ADH1.
Varicella-zoster virus recapitulates its immune evasive behaviour in matured hiPSC-derived neurospheroids.
Poised PABP-RNA hubs implement signal-dependent mRNA decay in development.
LINC01197 inhibits influenza A virus replication by serving as a PABPC1 decoy.
VP3 protein of Senecavirus A promotes viral IRES-driven translation and attenuates innate immunity by specifically relocalizing hnRNPA2B1.
Transcriptomic and proteomic profiling of bi-partite and tri-partite murine iPSC-derived neurospheroids under steady-state and inflammatory condition.
Cellular RNA-binding proteins LARP4 and PABPC1 synergistically facilitate viral translation of coronavirus PEDV.
Mechanism of cold exposure delaying wound healing in mice.
Two mechanisms repress cyclin B1 translation to maintain prophase arrest in mouse oocytes.
Stable structures or PABP1 loading protects cellular and viral RNAs against ISG20-mediated decay.
YTHDF1 promotes gallbladder cancer progression via post-transcriptional regulation of the m6A/UHRF1 axis.
Energy stress-induced circDDX21 promotes glycolysis and facilitates hepatocellular carcinogenesis.
Microglial lipid droplet accumulation in tauopathy brain is regulated by neuronal AMPK.
DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice.
EIF4A3-mediated biogenesis of circSTX6 promotes bladder cancer metastasis and cisplatin resistance.
LRPPRC promotes glycolysis by stabilising LDHA mRNA and its knockdown plus glutamine inhibitor induces synthetic lethality via m(6) A modification in triple-negative breast cancer.
G3BP1 and SLU7 Jointly Promote Immune Evasion by Downregulating MHC-I via PI3K/Akt Activation in Bladder Cancer.
Helicobacter Pylori-Enhanced hnRNPA2B1 Coordinates with PABPC1 to Promote Non-m(6)A Translation and Gastric Cancer Progression.
Primate-Specific DAZ Regulates Translation of Cell Proliferation-Related mRNAs and is Essential for Maintenance of Spermatogonia.
Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing.
LINE-1 mRNA 3' end dynamics shape its biology and retrotransposition potential.
Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation.
Stress granules plug and stabilize damaged endolysosomal membranes.
RNA binding protein AUF1/HNRNPD regulates nuclear export, stability and translation of SNCA transcripts.
T-2 toxin and deoxynivalenol (DON) exert distinct effects on stress granule formation depending on altered activity of SIRT1.
LncRNA BC promotes lung adenocarcinoma progression by modulating IMPAD1 alternative splicing.
LncRNA WDR11-AS1 Promotes Extracellular Matrix Synthesis in Osteoarthritis by Directly Interacting with RNA-Binding Protein PABPC1 to Stabilize SOX9 Expression.
CircPTK2/PABPC1/SETDB1 axis promotes EMT-mediated tumor metastasis and gemcitabine resistance in bladder cancer.
ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism.
An artificial intelligence network-guided signature for predicting outcome and immunotherapy response in lung adenocarcinoma patients based on 26 machine learning algorithms.
TIAR and FMRP shape pro-survival nascent proteome of leukemia cells in the bone marrow microenvironment.
Viral proteases activate the CARD8 inflammasome in the human cardiovascular system.
YTHDF3 modulates hematopoietic stem cells by recognizing RNA m(6)A modification on Ccnd1.
The deubiquitinating enzyme STAMBP is a newly discovered driver of triple-negative breast cancer progression that maintains RAI14 protein stability.
The kinesin motor KIF1C is a putative transporter of the exon junction complex in neuronal cells.
E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer.
Enhancer-Driven lncRNA BDNF-AS Induces Endocrine Resistance and Malignant Progression of Breast Cancer through the RNH1/TRIM21/mTOR Cascade.
NcPuf1 Is a Key Virulence Factor in Neospora caninum.
An oncopeptide regulates m(6)A recognition by the m(6)A reader IGF2BP1 and tumorigenesis.
Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.
An atlas of bloodstream-accessible bone marrow proteins for site-directed therapy of acute myeloid leukemia.
TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.
Douglas T, Nie P, Zhang J, Abdallah KS, Wu Z, McReynolds M, Iwai K, Peng J, Gilbert WV, Young LH, Crews CM
Nature cell biology 2026 May;28(5):930-945
Nature cell biology 2026 May;28(5):930-945
circPLEKHM1 promotes tumor growth and metastasis through enhancing FXR1-mediated protein translation in PDAC.
Yang Y, Li Z, Gao L, Ming Y, Zhang T, Ye Z, Liu W, Xiong Q, Xu X, Xu F, Guo J, Li J, Yang X, Peng Y, Zhu Q
Cancer letters 2026 Jun 1;647:218414
Cancer letters 2026 Jun 1;647:218414
TAG-PL: A Universal Proximity Labeling Platform for Mapping Mitochondrial Proteomes and Organelle Interactions under Stress.
Miao E, Yue X, Tao Z, Qin H, Ye M
Journal of proteome research 2026 Feb 6;25(2):966-977
Journal of proteome research 2026 Feb 6;25(2):966-977
A Circular RNA Promotes Tumor Metastasis through Stabilizing MSI2 Protein in Pancreatic Ductal Adenocarcinoma.
Li Z, Gao L, Yang Y, Ming Y, Liu W, Zhang T, Ye Z, Xu F, He J, Li J, Guo J, Yang X, Zhu Q, Peng Y
Research (Washington, D.C.) 2025;8:0918
Research (Washington, D.C.) 2025;8:0918
TOB Proteins Repress Translation via the CCR4-NOT Deadenylase Complex Independent of Deadenylation.
Miyazaki K, Tomohiro T, Funakami Y, Fukao A, Suzuki T, Yamamoto T, Fujiwara T
Genes to cells : devoted to molecular & cellular mechanisms 2025 Sep;30(5):e70042
Genes to cells : devoted to molecular & cellular mechanisms 2025 Sep;30(5):e70042
Targeting PABPC1: A therapeutic strategy of natural Ganoderma meroterpenoid LZ22 against triple-negative breast cancer proliferation.
Cai D, Chen YY, Hu H, Li S, Tao CT, Jiang QB, Hu JT, Jiang J, Cheng YX
Pharmacological research 2025 Nov;221:108004
Pharmacological research 2025 Nov;221:108004
CRTC2 Forms Co-Condensates with YTHDF2 That Enhance Translational Efficiency of m6A-Modified mRNAs to Drive Hepatocarcinogenesis and Lenvatinib Resistance.
Wang M, Zou F, Wang S, Yang Y, Xia C, Chen L, Liu B, Li L, Li MJ, Li H, Song W, Niu R, Yuan Z, Yang J, Li X, Chen K, Wu Z, Mi Z
Cancer research 2025 Jun 2;85(11):2046-2066
Cancer research 2025 Jun 2;85(11):2046-2066
The RNA-stability-independent role of the RNA m(6)A reader YTHDF2 in promoting protein translation to confer tumor chemotherapy resistance.
Liu T, Yang D, Wei Q, Wang Y, Tian L, Liu X, Yang Y, Luo Q, Xu J, Liu Y, Yang C, Zuo X, Luo F, Luo X, Zhao H, Li L, Xu J, Yu J, Ma S, Yu J, Yi P
Molecular cell 2025 Jun 19;85(12):2320-2336.e9
Molecular cell 2025 Jun 19;85(12):2320-2336.e9
A circular RNA overcomes acquired resistance to BET inhibitors by antagonizing IGF2BP2-mediated c-MYC translation in TNBC.
Guo J, Li K, Ming Y, Pan Y, Tan S, Ma H, Chen S, Duan Y, Peng Y
Proceedings of the National Academy of Sciences of the United States of America 2025 Jul 8;122(27):e2504320122
Proceedings of the National Academy of Sciences of the United States of America 2025 Jul 8;122(27):e2504320122
Engineering bi-directional chemically-modulated synthetic condensates for cellular control.
Zhen N, Yan Y, Zhu G, Zhu T, Zhang Q, Chen Q, Guo Y, Zhu J, Pan Q, Xie J
Nature communications 2025 Jul 17;16(1):6587
Nature communications 2025 Jul 17;16(1):6587
TRIM38 Inhibits Zika Virus by Upregulating RIG-I/MDA5 Pathway and Promoting Ubiquitin-Mediated Degradation of Viral NS3 Protein.
He J, Kuang Y, Xu K, Huang R, Yang X, Deng L, Feng X, Ren Y, Yang J, Yuan L
Viruses 2025 Jan 30;17(2)
Viruses 2025 Jan 30;17(2)
LINC00882, transcriptionally activated by CEBP-β and post-transcriptionally stabilized by METTL14-mediated m(6)A modification, exerts tumorigenesis by promoting PABPC1-mediated stabilization of ELK3 mRNA.
Gao ZX, Li CL, Zhang H, Zhang GH, Zhang Y, Guo XY, Tang ZY, Gao P, Liu HT
Oncogene 2025 Feb;44(6):363-377
Oncogene 2025 Feb;44(6):363-377
Eukaryotic translation elongation factor 1 alpha 1 facilitates coxsackievirus B replication through interacting with PABP, viral protein 3 CD and viral RNA.
Zhao S, Dong Y, Wang Y, Yang H, Luan T, He Y, Lin L, Chen Y, Fei Y, Wang G, Wang Y, Zhong Z, Qi N, Zhao W
Virulence 2025 Dec;16(1):2563925
Virulence 2025 Dec;16(1):2563925
Ribosome biogenesis as a potential therapeutic target in KRAS mutant colorectal cancer.
Tanaka Y, Sakahara M, Yamanaka H, Natsume Y, Kusama D, Kumegawa K, Yoshikawa H, Abe Y, Okabayashi K, Matui S, Kitagawa Y, Koshikawa N, Osumi H, Shinozaki E, Nagayama S, Adachi J, Maruyama R, Yao R
Nature communications 2025 Dec 27;17(1):1224
Nature communications 2025 Dec 27;17(1):1224
Transferrin receptor 1 (TfR1) functions as an entry receptor for scale drop disease virus to invade the host cell via clathrin-mediated endocytosis.
Chen J, Fu Y, Li Y, Weng S, Wang H, He J, Dong C
Journal of virology 2025 Aug 19;99(8):e0067125
Journal of virology 2025 Aug 19;99(8):e0067125
Inhibition of GRK2 reduced doxorubicin-induced oxidative stress and apoptosis through upregulating ADH1.
Jiang Z, Kan J, Wang D, Lv Y, Kong C, Wu L, Chen Y, Yang M, Gu Y, Chen S
Toxicology and applied pharmacology 2025 Apr;497:117261
Toxicology and applied pharmacology 2025 Apr;497:117261
Varicella-zoster virus recapitulates its immune evasive behaviour in matured hiPSC-derived neurospheroids.
Govaerts J, Van Breedam E, De Beuckeleer S, Goethals C, D'Incal CP, Di Stefano J, Van Calster S, Buyle-Huybrecht T, Boeren M, De Reu H, Paludan SR, Thiry M, Lebrun M, Sadzot-Delvaux C, Motaln H, Rogelj B, Van Weyenbergh J, De Vos WH, Vanden Berghe W, Ogunjimi B, Delputte P, Ponsaerts P
Frontiers in immunology 2024;15:1458967
Frontiers in immunology 2024;15:1458967
Poised PABP-RNA hubs implement signal-dependent mRNA decay in development.
Modic M, Kuret K, Steinhauser S, Faraway R, van Genderen E, Ruiz de Los Mozos I, Novljan J, Vičič Ž, Lee FCY, Ten Berge D, Luscombe NM, Ule J
Nature structural & molecular biology 2024 Sep;31(9):1439-1447
Nature structural & molecular biology 2024 Sep;31(9):1439-1447
LINC01197 inhibits influenza A virus replication by serving as a PABPC1 decoy.
Wang Y, Shi N, Zhang H, Luo J, Yan H, Hou H, Guan Z, Zhao L, Duan M
Veterinary research 2024 Sep 27;55(1):121
Veterinary research 2024 Sep 27;55(1):121
VP3 protein of Senecavirus A promotes viral IRES-driven translation and attenuates innate immunity by specifically relocalizing hnRNPA2B1.
Li L, Li X, Zhong H, Li M, Wan B, He W, Zhang Y, Du Y, Chen D, Zhang W, Ji P, Jiang D, Han S
Journal of virology 2024 Sep 17;98(9):e0122724
Journal of virology 2024 Sep 17;98(9):e0122724
Transcriptomic and proteomic profiling of bi-partite and tri-partite murine iPSC-derived neurospheroids under steady-state and inflammatory condition.
Di Stefano J, Garcia-Pupo L, Di Marco F, Motaln H, Govaerts J, Van Breedam E, Mateiu LM, Van Calster S, Ricciardi L, Quarta A, Verstraelen P, De Vos WH, Rogelj B, Cicalini I, De Laurenzi V, Del Boccio P, FitzGerald U, Vanden Berghe W, Verhoye M, Pieragostino D, Ponsaerts P
Brain, behavior, and immunity 2024 Oct;121:1-12
Brain, behavior, and immunity 2024 Oct;121:1-12
Cellular RNA-binding proteins LARP4 and PABPC1 synergistically facilitate viral translation of coronavirus PEDV.
Wang J, Zhang XZ, Sun XY, Tian WJ, Wang XJ
Veterinary microbiology 2024 Nov;298:110219
Veterinary microbiology 2024 Nov;298:110219
Mechanism of cold exposure delaying wound healing in mice.
Li FX, Liu JJ, Lei LM, Li YH, Xu F, Lin X, Cui RR, Zheng MH, Guo B, Shan SK, Tang KX, Li CC, Wu YY, Duan JY, Cao YC, Wu YL, He SY, Chen X, Wu F, Yuan LQ
Journal of nanobiotechnology 2024 Nov 20;22(1):723
Journal of nanobiotechnology 2024 Nov 20;22(1):723
Two mechanisms repress cyclin B1 translation to maintain prophase arrest in mouse oocytes.
Cheng S, Schuh M
Nature communications 2024 Nov 20;15(1):10044
Nature communications 2024 Nov 20;15(1):10044
Stable structures or PABP1 loading protects cellular and viral RNAs against ISG20-mediated decay.
Louvat C, Deymier S, Nguyen XN, Labaronne E, Noy K, Cariou M, Corbin A, Mateo M, Ricci EP, Fiorini F, Cimarelli A
Life science alliance 2024 May;7(5)
Life science alliance 2024 May;7(5)
YTHDF1 promotes gallbladder cancer progression via post-transcriptional regulation of the m6A/UHRF1 axis.
Chen J, Bai X, Zhang W, Yan Z, Liu Y, Zhou S, Wu X, He X, Yang A
Journal of cellular and molecular medicine 2024 May;28(9):e18328
Journal of cellular and molecular medicine 2024 May;28(9):e18328
Energy stress-induced circDDX21 promotes glycolysis and facilitates hepatocellular carcinogenesis.
Luo J, Yang Y, Zhang G, Fang D, Liu K, Mei Y, Wang F
Cell death & disease 2024 May 21;15(5):354
Cell death & disease 2024 May 21;15(5):354
Microglial lipid droplet accumulation in tauopathy brain is regulated by neuronal AMPK.
Li Y, Munoz-Mayorga D, Nie Y, Kang N, Tao Y, Lagerwall J, Pernaci C, Curtin G, Coufal NG, Mertens J, Shi L, Chen X
Cell metabolism 2024 Jun 4;36(6):1351-1370.e8
Cell metabolism 2024 Jun 4;36(6):1351-1370.e8
DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice.
Zou D, Li K, Su L, Liu J, Lu Y, Huang R, Li M, Mang X, Geng Q, Li P, Tang J, Yu Z, Zhang Z, Chen D, Miao S, Yu J, Yan W, Song W
Developmental cell 2024 Jul 8;59(13):1707-1723.e8
Developmental cell 2024 Jul 8;59(13):1707-1723.e8
EIF4A3-mediated biogenesis of circSTX6 promotes bladder cancer metastasis and cisplatin resistance.
Wei W, Liu K, Huang X, Tian S, Wang H, Zhang C, Ye J, Dong Y, An Z, Ma X, Wang B, Huang Y, Zhang X
Journal of experimental & clinical cancer research : CR 2024 Jan 2;43(1):2
Journal of experimental & clinical cancer research : CR 2024 Jan 2;43(1):2
LRPPRC promotes glycolysis by stabilising LDHA mRNA and its knockdown plus glutamine inhibitor induces synthetic lethality via m(6) A modification in triple-negative breast cancer.
Yu Y, Deng H, Wang W, Xiao S, Zheng R, Lv L, Wang H, Chen J, Zhang B
Clinical and translational medicine 2024 Feb;14(2):e1583
Clinical and translational medicine 2024 Feb;14(2):e1583
G3BP1 and SLU7 Jointly Promote Immune Evasion by Downregulating MHC-I via PI3K/Akt Activation in Bladder Cancer.
Zheng X, Chen J, Deng M, Ning K, Peng Y, Liu Z, Li X, Zhou Z, Tang H, Li Y, Kang T, Liu Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2305922
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2305922
Helicobacter Pylori-Enhanced hnRNPA2B1 Coordinates with PABPC1 to Promote Non-m(6)A Translation and Gastric Cancer Progression.
Yu Y, Yang YL, Chen XY, Chen ZY, Zhu JS, Zhang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(30):e2309712
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(30):e2309712
Primate-Specific DAZ Regulates Translation of Cell Proliferation-Related mRNAs and is Essential for Maintenance of Spermatogonia.
Ou N, Wang Y, Xu S, Luo J, Zhang C, Zhang Y, Shi X, Xiong M, Zhao L, Ji Z, Zhang Y, Zhao J, Bai H, Tian R, Li P, Zhi E, Huang Y, Chen W, Wang R, Jin Y, Wang D, Li Z, Chen H, Yao C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2400692
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2400692
Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing.
Maneix L, Iakova P, Lee CG, Moree SE, Lu X, Datar GK, Hill CT, Spooner E, King JCK, Sykes DB, Saez B, Di Stefano B, Chen X, Krause DS, Sahin E, Tsai FTF, Goodell MA, Berk BC, Scadden DT, Catic A
Nature cell biology 2024 Apr;26(4):593-603
Nature cell biology 2024 Apr;26(4):593-603
LINE-1 mRNA 3' end dynamics shape its biology and retrotransposition potential.
Janecki DM, Sen R, Szóstak N, Kajdasz A, Kordyś M, Plawgo K, Pandakov D, Philips A, Warkocki Z
Nucleic acids research 2024 Apr 12;52(6):3327-3345
Nucleic acids research 2024 Apr 12;52(6):3327-3345
Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation.
Wang C, Terrigno M, Li J, Distler T, Pandya NJ, Ebeling M, Tyanova S, Hoozemans JJM, Dijkstra AA, Fuchs L, Xiang S, Bonni A, Grüninger F, Jagasia R
Neuron 2023 Sep 6;111(17):2660-2674.e9
Neuron 2023 Sep 6;111(17):2660-2674.e9
Stress granules plug and stabilize damaged endolysosomal membranes.
Bussi C, Mangiarotti A, Vanhille-Campos C, Aylan B, Pellegrino E, Athanasiadi N, Fearns A, Rodgers A, Franzmann TM, Šarić A, Dimova R, Gutierrez MG
Nature 2023 Nov;623(7989):1062-1069
Nature 2023 Nov;623(7989):1062-1069
RNA binding protein AUF1/HNRNPD regulates nuclear export, stability and translation of SNCA transcripts.
Kattan FG, Koukouraki P, Anagnostopoulos AK, Tsangaris GT, Doxakis E
Open biology 2023 Nov;13(11):230158
Open biology 2023 Nov;13(11):230158
T-2 toxin and deoxynivalenol (DON) exert distinct effects on stress granule formation depending on altered activity of SIRT1.
Jiang T, Qi X, Lin R, Jiang J, Wen J, Deng Y
Ecotoxicology and environmental safety 2023 Jul 1;259:115028
Ecotoxicology and environmental safety 2023 Jul 1;259:115028
LncRNA BC promotes lung adenocarcinoma progression by modulating IMPAD1 alternative splicing.
Chen QW, Cai QQ, Yang Y, Dong S, Liu YY, Chen ZY, Kang CL, Qi B, Dong YW, Wu W, Zhuang LP, Shen YH, Meng ZQ, Wu XZ
Clinical and translational medicine 2023 Jan;13(1):e1129
Clinical and translational medicine 2023 Jan;13(1):e1129
LncRNA WDR11-AS1 Promotes Extracellular Matrix Synthesis in Osteoarthritis by Directly Interacting with RNA-Binding Protein PABPC1 to Stabilize SOX9 Expression.
Huang H, Yan J, Lan X, Guo Y, Sun M, Zhao Y, Zhang F, Sun J, Lu S
International journal of molecular sciences 2023 Jan 3;24(1)
International journal of molecular sciences 2023 Jan 3;24(1)
CircPTK2/PABPC1/SETDB1 axis promotes EMT-mediated tumor metastasis and gemcitabine resistance in bladder cancer.
Meng X, Xiao W, Sun J, Li W, Yuan H, Yu T, Zhang X, Dong W
Cancer letters 2023 Feb 1;554:216023
Cancer letters 2023 Feb 1;554:216023
ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism.
Sun L, Suo C, Zhang T, Shen S, Gu X, Qiu S, Zhang P, Wei H, Ma W, Yan R, Chen R, Jia W, Cao J, Zhang H, Gao P
Nature chemical biology 2023 Dec;19(12):1492-1503
Nature chemical biology 2023 Dec;19(12):1492-1503
An artificial intelligence network-guided signature for predicting outcome and immunotherapy response in lung adenocarcinoma patients based on 26 machine learning algorithms.
Zhang N, Zhang H, Liu Z, Dai Z, Wu W, Zhou R, Li S, Wang Z, Liang X, Wen J, Zhang X, Zhang B, Ouyang S, Zhang J, Luo P, Li X, Cheng Q
Cell proliferation 2023 Apr;56(4):e13409
Cell proliferation 2023 Apr;56(4):e13409
TIAR and FMRP shape pro-survival nascent proteome of leukemia cells in the bone marrow microenvironment.
Wolczyk M, Serwa R, Kominek A, Klejman A, Milek J, Chwałek M, Turos-Korgul L, Charzyńska A, Dabrowski M, Dziembowska M, Skorski T, Piwocka K, Podszywalow-Bartnicka P
iScience 2023 Apr 21;26(4):106543
iScience 2023 Apr 21;26(4):106543
Viral proteases activate the CARD8 inflammasome in the human cardiovascular system.
Nadkarni R, Chu WC, Lee CQE, Mohamud Y, Yap L, Toh GA, Beh S, Lim R, Fan YM, Zhang YL, Robinson K, Tryggvason K, Luo H, Zhong F, Ho L
The Journal of experimental medicine 2022 Oct 3;219(10)
The Journal of experimental medicine 2022 Oct 3;219(10)
YTHDF3 modulates hematopoietic stem cells by recognizing RNA m(6)A modification on Ccnd1.
Zhang X, Cong T, Wei L, Zhong B, Wang X, Sun J, Wang S, Xu MM, Zhu P, Jiang H, Wang J
Haematologica 2022 Oct 1;107(10):2381-2394
Haematologica 2022 Oct 1;107(10):2381-2394
The deubiquitinating enzyme STAMBP is a newly discovered driver of triple-negative breast cancer progression that maintains RAI14 protein stability.
Yang Q, Yan D, Zou C, Xue Q, Lin S, Huang Q, Li X, Tang D, Chen X, Liu J
Experimental & molecular medicine 2022 Nov;54(11):2047-2059
Experimental & molecular medicine 2022 Nov;54(11):2047-2059
The kinesin motor KIF1C is a putative transporter of the exon junction complex in neuronal cells.
Nagel M, Noß M, Xu J, Horn N, Ueffing M, Boldt K, Schüle R
RNA (New York, N.Y.) 2022 Dec 16;29(1):55-68
RNA (New York, N.Y.) 2022 Dec 16;29(1):55-68
E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer.
Li K, Zheng X, Tang H, Zang YS, Zeng C, Liu X, Shen Y, Pang Y, Wang S, Xie F, Lu X, Luo Y, Li Z, Bi W, Jia X, Huang T, Wei R, Huang K, Chen Z, Zhu Q, He Y, Zhang M, Gu Z, Xiao Y, Zhang X, Fletcher JA, Wang Y
The Journal of experimental medicine 2021 Aug 2;218(8)
The Journal of experimental medicine 2021 Aug 2;218(8)
Enhancer-Driven lncRNA BDNF-AS Induces Endocrine Resistance and Malignant Progression of Breast Cancer through the RNH1/TRIM21/mTOR Cascade.
Lin X, Dinglin X, Cao S, Zheng S, Wu C, Chen W, Li Q, Hu Q, Zheng F, Wu Z, Lin DC, Yao Y, Xu X, Xie Z, Liu Q, Yao H, Hu H
Cell reports 2020 Jun 9;31(10):107753
Cell reports 2020 Jun 9;31(10):107753
NcPuf1 Is a Key Virulence Factor in Neospora caninum.
Wang C, Yang C, Liu J, Liu Q
Pathogens (Basel, Switzerland) 2020 Dec 2;9(12)
Pathogens (Basel, Switzerland) 2020 Dec 2;9(12)
An oncopeptide regulates m(6)A recognition by the m(6)A reader IGF2BP1 and tumorigenesis.
Zhu S, Wang JZ, Chen D, He YT, Meng N, Chen M, Lu RX, Chen XH, Zhang XL, Yan GR
Nature communications 2020 Apr 3;11(1):1685
Nature communications 2020 Apr 3;11(1):1685
Purification of cross-linked RNA-protein complexes by phenol-toluol extraction.
Urdaneta EC, Vieira-Vieira CH, Hick T, Wessels HH, Figini D, Moschall R, Medenbach J, Ohler U, Granneman S, Selbach M, Beckmann BM
Nature communications 2019 Mar 1;10(1):990
Nature communications 2019 Mar 1;10(1):990
An atlas of bloodstream-accessible bone marrow proteins for site-directed therapy of acute myeloid leukemia.
Angenendt L, Reuter S, Kentrup D, Benk AS, Neumann F, Hüve J, Martens AC, Schwöppe C, Kessler T, Schmidt LH, Sauer T, Brand C, Mikesch JH, Lenz G, Mesters RM, Müller-Tidow C, Hartmann W, Wardelmann E, Neri D, Berdel WE, Roesli C, Schliemann C
Leukemia 2018 Feb;32(2):510-519
Leukemia 2018 Feb;32(2):510-519
TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.
Prpar Mihevc S, Baralle M, Buratti E, Rogelj B
Scientific reports 2016 Sep 26;6:33996
Scientific reports 2016 Sep 26;6:33996
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 10970-1-AP(PABPC1,PABP antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using PABPC1 antibody 10970-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas using 10970-1-AP(PABPC1,PABP antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas using 10970-1-AP(PABPC1,PABP antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue