66809-1-Ig

antibody from Proteintech Group

Targeting: PABPC1 PAB1, PABP1, PABPC2, PABPL1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66809-1-Ig

Provider

Proteintech Group

Product name

PABPC1,PABP antibody

Antibody type

Monoclonal

Description

PABPC1,PABP antibody (Cat. #66809-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, rat and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

3D8B5

Vial size

20ul, 150ul

References

Submitted references

Tuning tRNA synthetase inhibition reveals parabolic induction of stress granules limited in size and RNA content.

Baymiller M, Helton NS, Dodd B, Moon SL
RNA (New York, N.Y.) 2026 May 18;32(6):870-884

---

Hypoxia-driven phase separation of the PABP1/eIF4B complex forms stress granules and activates ChaC2 translation to promote polyunsaturated lipids-supported peritoneal metastasis in gastric cancer.

Lin Z, Gao Y, Zhang Q, Yang S, Chen Y, Ding H, Peng W, Zhang X, Nurzat Y, Hu J, Liao W, Xiong B, Xiao M, Zhang X
Cancer letters 2026 May 1;645:218392

---

PABPC1 regulates EOPE pathogenesis through modulating TMBIM4 mRNA expression and stability.

Zhao S, Lv N, Liu T, Sun Y, Li P
European journal of medical research 2026 Mar 5;

---

An engineered linear cap-independent mRNA vaccine with intrinsic adjuvanticity induces potent anti-tumor immunity in mice.

Yu H, Yang Y, Lin P, Liu C, Wen Y, Huang Z, Fang Z, Hu Z, Huang S
Nature communications 2026 Feb 26;17(1)

---

PABPC1-induced stabilization of PGK1 mRNA reduces apoptosis and sunitinib sensitivity in renal cell carcinoma by suppressing endoplasmic reticulum stress.

Chen X, Cao S, Jia T, Shi C, Yang Z, Liang Q, Zhang X, Gu L, Ma X, Huang Q, Li X
Cell death & disease 2026 Apr 3;17(1)

---

tRNA synthetase activity is required for stress granule and P-body assembly.

Baymiller M, Helton NS, Dodd B, Moon SL
Genes & development 2026 Apr 1;40(7-8):475-497

---

NSCLC cells sustain phase separation of cytoplasmic membrane-less organelles to protect themselves against cisplatin treatment.

Li NN, Rao LL, Su D, Liu BH, Ma GQ, Wang HF, Zhang ZL, Ying Z
Acta pharmacologica Sinica 2025 Sep;46(9):2522-2533

---

DDX3 Regulates the Cap-Independent Translation of the Japanese Encephalitis Virus via Its Interactions with PABP1 and the Untranslated Regions of the Viral Genome.

Li C, Zhang L, Tang C, Chen X, Shi J, Li Q, Jiao X, Guo J, Wang B, Bu K, Wahaab A, Yuan Y, Sun MA, Li Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(27):e2502493

---

Helicobacter Pylori-Enhanced hnRNPA2B1 Coordinates with PABPC1 to Promote Non-m(6)A Translation and Gastric Cancer Progression.

Yu Y, Yang YL, Chen XY, Chen ZY, Zhu JS, Zhang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(30):e2309712

---

Deubiquitinating PABPC1 by USP10 upregulates CLK2 translation to promote tumor progression in pancreatic ductal adenocarcinoma.

Li TJ, Jin KZ, Zhou HY, Liao ZY, Zhang HR, Shi SM, Lin MX, Chai SJ, Fei QL, Ye LY, Yu XJ, Wu WD
Cancer letters 2023 Nov 1;576:216411

---

Pyridostigmine ameliorates preeclamptic features in pregnant rats by inhibiting tumour necrosis factor-α synthetsis and antagonizing tumour necrosis factor-α-related effects.

Issotina Zibrila A, Wang Z, Ali MA, Osei JA, Sun Y, Zafar S, Liu K, Li C, Kang Y, Liu J
Journal of hypertension 2021 Sep 1;39(9):1774-1789

---

The prognostic impacts of PABPC1 expression on gastric cancer patients.

An T, Deng L, Wang Y, Yang Z, Chai C, Ouyang J, Lu X, Zhang C
Future oncology (London, England) 2021 Nov;17(33):4471-4479