Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 15124-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15124-1-AP, RRID:AB_2248132
- Product name
- GSTO1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GSTO1 antibody (Cat. #15124-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The mouse retinal pigment epithelium mounts an innate immune defense response following retinal detachment.
Glutathione S-transferase omega class 1 (GSTO1)-associated large extracellular vesicles are involved in tumor-associated macrophage-mediated cisplatin resistance in bladder cancer.
Nucleophilic covalent ligand discovery for the cysteine redoxome.
SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation.
ASC deglutathionylation is a checkpoint for NLRP3 inflammasome activation.
TMT-based quantitative proteomic analysis of porcine muscle associated with postmortem meat quality.
GSTO1 regulates insulin biosynthesis in pancreatic β cells.
GSTO1 acts as a mediator in sodium fluoride-induced alterations of learning and memory related factors expressions in the hippocampus cell line.
Inhibition of NRF2 signaling and increased reactive oxygen species during embryogenesis in a rat model of retinoic acid-induced neural tube defects.
Proteomic profiling of human decidual immune proteins during Toxoplasma gondii infection.
The interaction of arsenic and N-butyl-N-(4-hydroxybutyl)nitrosamine on urothelial carcinogenesis in mice.
Selenophosphate synthetase 1 is an essential protein with roles in regulation of redox homoeostasis in mammals.
Downregulation of glutathione S-transferase M1 protein in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced mouse bladder carcinogenesis.
Abcouwer SF, Miglioranza Scavuzzi B, Kish PE, Kong D, Shanmugam S, Le XA, Yao J, Hager H, Zacks DN
Journal of neuroinflammation 2024 Mar 25;21(1):74
Journal of neuroinflammation 2024 Mar 25;21(1):74
Glutathione S-transferase omega class 1 (GSTO1)-associated large extracellular vesicles are involved in tumor-associated macrophage-mediated cisplatin resistance in bladder cancer.
Pan YC, Chu PY, Lin CC, Hsieh CY, Hsu WY, Shyur LF, Yang JC, Chang WC, Wu YC
Molecular oncology 2024 Aug;18(8):1866-1884
Molecular oncology 2024 Aug;18(8):1866-1884
Nucleophilic covalent ligand discovery for the cysteine redoxome.
Fu L, Jung Y, Tian C, Ferreira RB, Cheng R, He F, Yang J, Carroll KS
Nature chemical biology 2023 Nov;19(11):1309-1319
Nature chemical biology 2023 Nov;19(11):1309-1319
SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation.
Zhang W, Dai J, Hou G, Liu H, Zheng S, Wang X, Lin Q, Zhang Y, Lu M, Gong Y, Xiang Z, Yu Y, Hu Y
Molecular cell 2023 Dec 7;83(23):4352-4369.e8
Molecular cell 2023 Dec 7;83(23):4352-4369.e8
ASC deglutathionylation is a checkpoint for NLRP3 inflammasome activation.
Li S, Wang L, Xu Z, Huang Y, Xue R, Yue T, Xu L, Gong F, Bai S, Wu Q, Liu J, Lin B, Zhang H, Xue Y, Xu P, Hou J, Yang X, Jin T, Zhou R, Lou J, Xu T, Bai L
The Journal of experimental medicine 2021 Sep 6;218(9)
The Journal of experimental medicine 2021 Sep 6;218(9)
TMT-based quantitative proteomic analysis of porcine muscle associated with postmortem meat quality.
Hou X, Liu Q, Meng Q, Wang L, Yan H, Zhang L, Wang L
Food chemistry 2020 Oct 30;328:127133
Food chemistry 2020 Oct 30;328:127133
GSTO1 regulates insulin biosynthesis in pancreatic β cells.
Wang L, Lei L, Xu T, Wang Y
Biochemical and biophysical research communications 2020 Apr 16;524(4):936-942
Biochemical and biophysical research communications 2020 Apr 16;524(4):936-942
GSTO1 acts as a mediator in sodium fluoride-induced alterations of learning and memory related factors expressions in the hippocampus cell line.
Wang J, Gao Y, Cheng X, Yang J, Zhao Y, Xu H, Zhu Y, Yan Z, Manthari RK, Ommati MM, Wang J
Chemosphere 2019 Jul;226:201-209
Chemosphere 2019 Jul;226:201-209
Inhibition of NRF2 signaling and increased reactive oxygen species during embryogenesis in a rat model of retinoic acid-induced neural tube defects.
Liu D, Xue J, Liu Y, Gu H, Wei X, Ma W, Luo W, Ma L, Jia S, Dong N, Huang J, Wang Y, Yuan Z
Neurotoxicology 2018 Dec;69:84-92
Neurotoxicology 2018 Dec;69:84-92
Proteomic profiling of human decidual immune proteins during Toxoplasma gondii infection.
Zhang D, Sun X, Ren L, Yang C, Liu X, Zhang H, Jiang Y, Hu X
Journal of proteomics 2018 Aug 30;186:28-37
Journal of proteomics 2018 Aug 30;186:28-37
The interaction of arsenic and N-butyl-N-(4-hydroxybutyl)nitrosamine on urothelial carcinogenesis in mice.
Dai YC, Wang SC, Haque MM, Lin WH, Lin LC, Chen CH, Liu YW
PloS one 2017;12(10):e0186214
PloS one 2017;12(10):e0186214
Selenophosphate synthetase 1 is an essential protein with roles in regulation of redox homoeostasis in mammals.
Tobe R, Carlson BA, Huh JH, Castro NP, Xu XM, Tsuji PA, Lee SG, Bang J, Na JW, Kong YY, Beaglehole D, Southon E, Seifried H, Tessarollo L, Salomon DS, Schweizer U, Gladyshev VN, Hatfield DL, Lee BJ
The Biochemical journal 2016 Jul 15;473(14):2141-54
The Biochemical journal 2016 Jul 15;473(14):2141-54
Downregulation of glutathione S-transferase M1 protein in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced mouse bladder carcinogenesis.
Chuang JJ, Dai YC, Lin YL, Chen YY, Lin WH, Chan HL, Liu YW
Toxicology and applied pharmacology 2014 Sep 15;279(3):322-330
Toxicology and applied pharmacology 2014 Sep 15;279(3):322-330
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 15124-1-AP(GSTO1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using GSTO1 antibody 15124-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 15124-1-AP(GSTO1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 15124-1-AP(GSTO1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue