BS8004

antibody from Bioworld Technology, Inc
Targeting: GSTO1 GSTTLp28, P28
Provider product page for BS8004
Western blot
Immunohistochemistry

Antibody data

Product number
BS8004 - Provider product page
Provider
Bioworld Technology, Inc
Product name
GSTO1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human GSTO1.
Description
GSTO1 (glutathione S-transferase omega 1), also known as p28 or GSTTLp28, is a 241 amino acid protein that localizes to the cytoplasm and contains both an N-terminal and a C-terminal GST domain. Expressed ubiquitously with highest expression in heart, liver and skeletal muscle, GSTO1 exists as a homodimer that functions as both a glutathione-dependent thiol transferase and a dehydroascorbate reductase. Specifically, GSTO1 catalyzes the reaction of glutathione with a wide variety of organic compounds to form thioethers, a process that is essential for the metabolism and detoxification of a variety of xenobiotics and carcinogens. Human GSTO1 shares 70% sequence homology with its rodent counterpart, suggesting a conserved role between species. Polymorphisms in the gene encoding GSTO1 may be associated with the development of childhood acute lymphoblastic leukemia, Parkinson£ªs disease and Alzheimer disease.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GSTO1 protein structure - BS8004 shown in red.