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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Product number
- 23374-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ZCCHC8 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ZCCHC8 antibody (Cat. #23374-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references RBMX involves in telomere stability maintenance by regulating TERRA expression.
Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation.
Globally reduced N(6)-methyladenosine (m(6)A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration.
Concurrent binding to DNA and RNA facilitates the pluripotency reprogramming activity of Sox2.
Nuclear Exosome Targeting Complex Core Factor Zcchc8 Regulates the Degradation of LINE1 RNA in Early Embryos and Embryonic Stem Cells.
mRNAs are sorted for export or degradation before passing through nuclear speckles.
Liu J, Zheng T, Chen D, Huang J, Zhao Y, Ma W, Liu H
PLoS genetics 2023 Sep;19(9):e1010937
PLoS genetics 2023 Sep;19(9):e1010937
Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation.
Torre D, Fstkchyan YS, Ho JSY, Cheon Y, Patel RS, Degrace EJ, Mzoughi S, Schwarz M, Mohammed K, Seo JS, Romero-Bueno R, Demircioglu D, Hasson D, Tang W, Mahajani SU, Campisi L, Zheng S, Song WS, Wang YC, Shah H, Francoeur N, Soto J, Salfati Z, Weirauch MT, Warburton P, Beaumont K, Smith ML, Mulder L, Villalta SA, Kessenbrock K, Jang C, Lee D, De Rubeis S, Cobos I, Tam O, Hammell MG, Seldin M, Shi Y, Basu U, Sebastiano V, Byun M, Sebra R, Rosenberg BR, Benner C, Guccione E, Marazzi I
Molecular cell 2023 Dec 7;83(23):4255-4271.e9
Molecular cell 2023 Dec 7;83(23):4255-4271.e9
Globally reduced N(6)-methyladenosine (m(6)A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration.
Li Y, Dou X, Liu J, Xiao Y, Zhang Z, Hayes L, Wu R, Fu X, Ye Y, Yang B, Ostrow LW, He C, Sun S
Nature neuroscience 2023 Aug;26(8):1328-1338
Nature neuroscience 2023 Aug;26(8):1328-1338
Concurrent binding to DNA and RNA facilitates the pluripotency reprogramming activity of Sox2.
Hou L, Wei Y, Lin Y, Wang X, Lai Y, Yin M, Chen Y, Guo X, Wu S, Zhu Y, Yuan J, Tariq M, Li N, Sun H, Wang H, Zhang X, Chen J, Bao X, Jauch R
Nucleic acids research 2020 Apr 17;48(7):3869-3887
Nucleic acids research 2020 Apr 17;48(7):3869-3887
Nuclear Exosome Targeting Complex Core Factor Zcchc8 Regulates the Degradation of LINE1 RNA in Early Embryos and Embryonic Stem Cells.
Wu Y, Liu W, Chen J, Liu S, Wang M, Yang L, Chen C, Qi M, Xu Y, Qiao Z, Yan R, Kou X, Zhao Y, Shen B, Yin J, Wang H, Gao Y, Gao S
Cell reports 2019 Nov 19;29(8):2461-2472.e6
Cell reports 2019 Nov 19;29(8):2461-2472.e6
mRNAs are sorted for export or degradation before passing through nuclear speckles.
Fan J, Kuai B, Wang K, Wang L, Wang Y, Wu X, Chi B, Li G, Cheng H
Nucleic acids research 2018 Sep 19;46(16):8404-8416
Nucleic acids research 2018 Sep 19;46(16):8404-8416
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