Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [2]
- Other assay [1]
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Validation data
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- Product number
- PA5-18670 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- ACOX2 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- This antibody is predicted to react with rabbit based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.
- Reactivity
- Human
- Host
- Goat
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/mL
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references ACOX2 is a prognostic marker and impedes the progression of hepatocellular carcinoma via PPARĪ± pathway.
Zhang Q, Zhang Y, Sun S, Wang K, Qian J, Cui Z, Tao T, Zhou J
Cell death & disease 2021 Jan 4;12(1):15
Cell death & disease 2021 Jan 4;12(1):15
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- PA5-18670 (0.5 µg/mL) in Human Liver lysate with (B) and without (A) blocking with the immunising peptide, the primary antibody incubation was 1 hour and detected by chemiluminescence.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- PA5-18670 (0.5 µg/mL) in Human Liver lysate with (B) and without (A) blocking with the immunising peptide, the primary antibody incubation was 1 hour and detected by chemiluminescence.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Fig. 5 ACOX2 is downregulated in liver cancer. A The expression of ACOX2 gene in liver cancer tissues and paired paracancer tissues by using RT-qPCR. B The expression of ACOX2 protein in liver cancer tissues and normal control tissues was detected by using immunohistochemistry. The expression distribution of ACOX2 in normal liver tissue and HCC patient samples was evaluated in the THPA database. C The expression of ACOX2 mRNA in normal liver cells and liver cancer cells by using RT-qPCR (* P < 0.05 and ** P < 0.01). D The protein expression of ACOX2 in normal liver cells and liver cancer cells by Western blot (*** P < 0.001). E The mRNA expression of ACOX2 in the TCGA dataset (*** P < 0.001). F Survival analysis of the association between ACOX2 and overall survival time in HCC patients (based on the TCGA data, P = 0.0326).