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- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 25009-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ZC3H12A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ZC3H12A antibody (Cat. #25009-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma.
MCPIP1 alleviates depressive‑like behaviors in mice by inhibiting the TLR4/TRAF6/NF‑κB pathway to suppress neuroinflammation.
Metformin Protects Against Acute Kidney Injury Induced by Lipopolysaccharide via Up-Regulating the MCPIP1/SIRT1 Pathway.
MCPIP1 alleviates inflammatory response through inducing autophagy in Aspergillus fumigatus keratitis.
Increased expression of CDKN1A/p21 in HIV-1 controllers is correlated with upregulation of ZC3H12A/MCPIP1.
MCPIP1 regulates RORα expression to protect against liver injury induced by lipopolysaccharide via modulation of miR-155.
MCPIP1 alleviated lipopolysaccharide-induced liver injury by regulating SIRT1 via modulation of microRNA-9.
Klf4 Alleviates Lipopolysaccharide-Induced Inflammation by Inducing Expression of MCP-1 Induced Protein 1 to Deubiquitinate TRAF6.
TLR4 signaling pathway mediates the LPS/ischemia-induced expression of monocytechemotactic protein-induced protein 1 in microglia.
MCPIP1 inhibits coxsackievirus B3 replication by targeting viral RNA and negatively regulates virus-induced inflammation.
MCPIP1/Regnase-1 Restricts IL-17A- and IL-17C-Dependent Skin Inflammation.
Pal SK, Tran B, Haanen JBAG, Hurwitz ME, Sacher A, Tannir NM, Budde LE, Harrison SJ, Klobuch S, Patel SS, Meza L, Dequeant ML, Ma A, He QA, Williams LM, Keegan A, Gurary EB, Dar H, Karnik S, Guo C, Heath H, Yuen RR, Morrow PK, Agarwal N, Srour SA
Cancer discovery 2024 Jul 1;14(7):1176-1189
Cancer discovery 2024 Jul 1;14(7):1176-1189
MCPIP1 alleviates depressive‑like behaviors in mice by inhibiting the TLR4/TRAF6/NF‑κB pathway to suppress neuroinflammation.
An Q, Xia J, Pu F, Shi S
Molecular medicine reports 2024 Jan;29(1)
Molecular medicine reports 2024 Jan;29(1)
Metformin Protects Against Acute Kidney Injury Induced by Lipopolysaccharide via Up-Regulating the MCPIP1/SIRT1 Pathway.
Zhang WL, Zhang LJ, Liang P, Fang HL, Wang XL, Liu YJ, Deng HF
Biochemical genetics 2024 Feb 12;
Biochemical genetics 2024 Feb 12;
MCPIP1 alleviates inflammatory response through inducing autophagy in Aspergillus fumigatus keratitis.
Han F, Shen L, Ma H, Wang L, Guo H, Wu X
International immunopharmacology 2022 Dec;113(Pt A):109279
International immunopharmacology 2022 Dec;113(Pt A):109279
Increased expression of CDKN1A/p21 in HIV-1 controllers is correlated with upregulation of ZC3H12A/MCPIP1.
de Azevedo SSD, Ribeiro-Alves M, Côrtes FH, Delatorre E, Spangenberg L, Naya H, Seito LN, Hoagland B, Grinsztejn B, Veloso VG, Morgado MG, Souza TML, Bello G
Retrovirology 2020 Jul 2;17(1):18
Retrovirology 2020 Jul 2;17(1):18
MCPIP1 regulates RORα expression to protect against liver injury induced by lipopolysaccharide via modulation of miR-155.
Li Z, Han S, Jia Y, Yang Y, Han F, Wu G, Li X, Zhang W, Jia W, He X, Han J, Hu D
Journal of cellular physiology 2019 Sep;234(9):16562-16572
Journal of cellular physiology 2019 Sep;234(9):16562-16572
MCPIP1 alleviated lipopolysaccharide-induced liver injury by regulating SIRT1 via modulation of microRNA-9.
Han S, Li Z, Ji P, Jia Y, Bai X, Cai W, Li X, Yang C, Yang Y, Yang K, Wu G, Zhang W, Hu D
Journal of cellular physiology 2019 Dec;234(12):22450-22462
Journal of cellular physiology 2019 Dec;234(12):22450-22462
Klf4 Alleviates Lipopolysaccharide-Induced Inflammation by Inducing Expression of MCP-1 Induced Protein 1 to Deubiquitinate TRAF6.
Li Z, Jia Y, Han S, Wang X, Han F, Zhang J, Zhang W, Guan H, Hu D
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2278-2290
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2278-2290
TLR4 signaling pathway mediates the LPS/ischemia-induced expression of monocytechemotactic protein-induced protein 1 in microglia.
Chen S, Lyu C, Zhou J, Huang S, Zhang Y, Liu G, Liu K, Chen D, Hu Y, Zhou L, Gu Y
Neuroscience letters 2018 Nov 1;686:33-40
Neuroscience letters 2018 Nov 1;686:33-40
MCPIP1 inhibits coxsackievirus B3 replication by targeting viral RNA and negatively regulates virus-induced inflammation.
Li M, Yan K, Wei L, Yang Y, Qian Q, Xu W
Medical microbiology and immunology 2018 Feb;207(1):27-38
Medical microbiology and immunology 2018 Feb;207(1):27-38
MCPIP1/Regnase-1 Restricts IL-17A- and IL-17C-Dependent Skin Inflammation.
Monin L, Gudjonsson JE, Childs EE, Amatya N, Xing X, Verma AH, Coleman BM, Garg AV, Killeen M, Mathers A, Ward NL, Gaffen SL
Journal of immunology (Baltimore, Md. : 1950) 2017 Jan 15;198(2):767-775
Journal of immunology (Baltimore, Md. : 1950) 2017 Jan 15;198(2):767-775
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Raji cells were subjected to SDS PAGE followed by western blot with 25009-1-AP( ZC3H12A Antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ZC3H12A antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ZC3H12A. This antibody recognizes human, mouse antigen. The ZC3H12A antibody has been validated for the following applications: ELISA, WB, IHC analysis.
