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- Antigen structure
- References [16]
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- Product number
- 17601-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17601-1-AP, RRID:AB_2095372
- Product name
- DNALI1 antibody
- Antibody type
- Polyclonal
- Description
- DNALI1 antibody (Cat. #17601-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Axonemal Dynein Visualized in Primary Cilia via Expansion Microscopy.
CFAP300 loss-of-function variant causes primary ciliary dyskinesia and male infertility via disrupting sperm flagellar assembly and acrosome formation.
A novel frameshift variant in AXDND1 may cause multiple morphological abnormalities of the sperm flagella in a consanguineous Pakistani family.
Ultrastructure expansion microscopy of axonemal dynein in islet primary cilia.
Novel bi-allelic DNAH3 variants cause oligoasthenoteratozoospermia.
DNAH3 deficiency causes flagellar inner dynein arm loss and male infertility in humans and mice.
ZMYND12 serves as an IDAd subunit that is essential for sperm motility in mice.
Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice.
DNALI1 Promotes Neurodegeneration after Traumatic Brain Injury via Inhibition of Autophagosome-Lysosome Fusion.
PIH1D3-knockout rats exhibit full ciliopathy features and dysfunctional pre-assembly and loading of dynein arms in motile cilia.
Dnali1 is required for sperm motility and male fertility in mice.
CCDC183 is essential for cytoplasmic invagination around the flagellum during spermiogenesis and male fertility.
CFAP70 is a solid and valuable target for the genetic diagnosis of oligo-astheno-teratozoospermia in infertile men.
DNALI1 interacts with the MEIG1/PACRG complex within the manchette and is required for proper sperm flagellum assembly in mice.
The motor domain of testis-enriched kinesin KIF9 is essential for its localization in the mouse flagellum.
DNAH2 is a novel candidate gene associated with multiple morphological abnormalities of the sperm flagella.
Dong X, Jo JH, Hughes J
Cytoskeleton (Hoboken, N.J.) 2026 May;83(5):224-236
Cytoskeleton (Hoboken, N.J.) 2026 May;83(5):224-236
CFAP300 loss-of-function variant causes primary ciliary dyskinesia and male infertility via disrupting sperm flagellar assembly and acrosome formation.
Yin HY, Zhou YQ, Shen QS, Chen ZW, Li JR, Wu H, Cao YX, Guo R, Song B
Asian journal of andrology 2025 Nov 1;27(6):743-750
Asian journal of andrology 2025 Nov 1;27(6):743-750
A novel frameshift variant in AXDND1 may cause multiple morphological abnormalities of the sperm flagella in a consanguineous Pakistani family.
Ali I, Yang ML, Rahim F, Ali H, Zeb A, Ahmad N, Raza Y, Yue W, Shoaib M, Abbas T, Shah W, Ma H, Zhang H, Yin H, Shi QH
Asian journal of andrology 2025 Nov 1;27(6):691-696
Asian journal of andrology 2025 Nov 1;27(6):691-696
Ultrastructure expansion microscopy of axonemal dynein in islet primary cilia.
Dong X, Jo JH, Hughes J
bioRxiv : the preprint server for biology 2025 Jan 23;
bioRxiv : the preprint server for biology 2025 Jan 23;
Novel bi-allelic DNAH3 variants cause oligoasthenoteratozoospermia.
Li S, Zhang Z, Xie L, Zhao Y, Chen H, Zhang S, Cai Y, Ren B, Liu W, Tang S, Sha Y
Frontiers in endocrinology 2024;15:1462509
Frontiers in endocrinology 2024;15:1462509
DNAH3 deficiency causes flagellar inner dynein arm loss and male infertility in humans and mice.
Wang X, Shen G, Yang Y, Jiang C, Ruan T, Yang X, Zhuo L, Zhang Y, Ou Y, Zhao X, Long S, Tang X, Lin T, Shen Y
eLife 2024 Nov 6;13
eLife 2024 Nov 6;13
ZMYND12 serves as an IDAd subunit that is essential for sperm motility in mice.
Wang C, Xie Q, Xia X, Zhang C, Jiang S, Wang S, Zhang X, Hua R, Xue J, Zheng H
Cellular and molecular life sciences : CMLS 2024 Jul 27;81(1):317
Cellular and molecular life sciences : CMLS 2024 Jul 27;81(1):317
Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice.
O'Shea TM, Ao Y, Wang S, Ren Y, Cheng AL, Kawaguchi R, Shi Z, Swarup V, Sofroniew MV
Nature neuroscience 2024 Aug;27(8):1505-1521
Nature neuroscience 2024 Aug;27(8):1505-1521
DNALI1 Promotes Neurodegeneration after Traumatic Brain Injury via Inhibition of Autophagosome-Lysosome Fusion.
Ding X, Cao S, Wang Q, Du B, Lu K, Qi S, Cheng Y, Tuo QZ, Liang W, Lei P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(15):e2306399
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(15):e2306399
PIH1D3-knockout rats exhibit full ciliopathy features and dysfunctional pre-assembly and loading of dynein arms in motile cilia.
Zhang T, Cui S, Xiong X, Liu Y, Cao Q, Xia XG, Zhou H
Frontiers in cell and developmental biology 2023;11:1282787
Frontiers in cell and developmental biology 2023;11:1282787
Dnali1 is required for sperm motility and male fertility in mice.
Zhou Y, Wang Y, Chen J, Wu B, Tang S, Zhang F, Liu C, Wang L
Basic and clinical andrology 2023 Nov 23;33(1):32
Basic and clinical andrology 2023 Nov 23;33(1):32
CCDC183 is essential for cytoplasmic invagination around the flagellum during spermiogenesis and male fertility.
Shimada K, Ikawa M
Development (Cambridge, England) 2023 Nov 1;150(21)
Development (Cambridge, England) 2023 Nov 1;150(21)
CFAP70 is a solid and valuable target for the genetic diagnosis of oligo-astheno-teratozoospermia in infertile men.
Jin HJ, Wang JL, Geng XY, Wang CY, Wang BB, Chen SR
EBioMedicine 2023 Jul;93:104675
EBioMedicine 2023 Jul;93:104675
DNALI1 interacts with the MEIG1/PACRG complex within the manchette and is required for proper sperm flagellum assembly in mice.
Yap YT, Li W, Huang Q, Zhou Q, Zhang D, Sheng Y, Mladenovic-Lucas L, Yee SP, Orwig KE, Granneman JG, Williams DC Jr, Hess RA, Toure A, Zhang Z
eLife 2023 Apr 21;12
eLife 2023 Apr 21;12
The motor domain of testis-enriched kinesin KIF9 is essential for its localization in the mouse flagellum.
Miyata H, Oyama Y, Kaneda Y, Ikawa M
Experimental animals 2022 Feb 9;71(1):46-52
Experimental animals 2022 Feb 9;71(1):46-52
DNAH2 is a novel candidate gene associated with multiple morphological abnormalities of the sperm flagella.
Li Y, Sha Y, Wang X, Ding L, Liu W, Ji Z, Mei L, Huang X, Lin S, Kong S, Lu J, Qin W, Zhang X, Zhuang J, Tang Y, Lu Z
Clinical genetics 2019 May;95(5):590-600
Clinical genetics 2019 May;95(5):590-600
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DNALI1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DNALI1. This antibody recognizes human, mouse, rat antigen. The DNALI1 antibody has been validated for the following applications: ELISA, WB analysis.
