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- Product number
- ABIN153073 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Polymerase (DNA Directed), beta (POLB) antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified
- Reactivity
- Human, Mouse, Rat, Bovine, Hamster, Xenopus
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 18S
- Vial size
- 0.5 mL
- Storage
- Store at 4°C. Do not freeze.
- Handling
- Do not freeze.
Submitted references ABT-888 and quinacrine induced apoptosis in metastatic breast cancer stem cells by inhibiting base excision repair via adenomatous polyposis coli.
Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade.
Age-dependent decline of DNA base excision repair activity in rat cortical neurons.
A platinum agent resistance gene, POLB, is a prognostic indicator in colorectal cancer.
DNA polymerase beta interacts with TRF2 and induces telomere dysfunction in a murine mammary cell line.
Phorbol ester abrogates up-regulation of DNA polymerase beta by DNA-alkylating agents in Chinese hamster ovary cells.
Siddharth S, Nayak D, Nayak A, Das S, Kundu CN
DNA repair 2016 Sep;45:44-55
DNA repair 2016 Sep;45:44-55
Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade.
Preet R, Siddharth S, Satapathy SR, Das S, Nayak A, Das D, Wyatt MD, Kundu CN
Biochemical pharmacology 2016 Apr 1;105:23-33
Biochemical pharmacology 2016 Apr 1;105:23-33
Age-dependent decline of DNA base excision repair activity in rat cortical neurons.
Swain U, Rao KS
Mechanisms of ageing and development 2012 Apr;133(4):186-94
Mechanisms of ageing and development 2012 Apr;133(4):186-94
A platinum agent resistance gene, POLB, is a prognostic indicator in colorectal cancer.
Iwatsuki M, Mimori K, Yokobori T, Tanaka F, Tahara K, Inoue H, Baba H, Mori M
Journal of surgical oncology 2009 Sep 1;100(3):261-6
Journal of surgical oncology 2009 Sep 1;100(3):261-6
DNA polymerase beta interacts with TRF2 and induces telomere dysfunction in a murine mammary cell line.
Fotiadou P, Henegariu O, Sweasy JB
Cancer research 2004 Jun 1;64(11):3830-7
Cancer research 2004 Jun 1;64(11):3830-7
Phorbol ester abrogates up-regulation of DNA polymerase beta by DNA-alkylating agents in Chinese hamster ovary cells.
Srivastava DK, Rawson TY, Showalter SD, Wilson SH
The Journal of biological chemistry 1995 Jul 7;270(27):16402-8
The Journal of biological chemistry 1995 Jul 7;270(27):16402-8
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- Experimental details
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- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
