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ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [16]
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- Other assay [1]
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- Product number
- MA5-13899 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- POLB Monoclonal Antibody (18S)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- MA5-13899 targets Rat DNA Polymerase beta in IP and WB applications and shows reactivity with Bovine, Hamster, Human, mouse, Rat, and Xenopus laevis samples. The MA5-13899 immunogen is rat DNA polymerase beta protein.
- Reactivity
- Human, Mouse, Rat, Bovine, Hamster, Xenopus
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 18S
- Vial size
- 500 µL
- Concentration
- 0.2 mg/mL
- Storage
- 4° C
Submitted references FOXO3 Transcription Factor Is Essential for Protecting Hematopoietic Stem and Progenitor Cells from Oxidative DNA Damage.
HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β.
Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice.
Molecular characterization of spontaneous mesenchymal stem cell transformation.
Methylation of DNA polymerase beta by protein arginine methyltransferase 1 regulates its binding to proliferating cell nuclear antigen.
Possible role of DNA polymerase beta in protecting human bronchial epithelial cells against cytotoxicity of hydroquinone.
Connexin-specific cell-to-cell transfer of short interfering RNA by gap junctions.
The overexpression of specialized DNA polymerases in cancer.
A new XRCC1-containing complex and its role in cellular survival of methyl methanesulfonate treatment.
Human and rodent cell lines showing no differences in the induction but differing in the repair kinetics of radiation-induced DNA base damage.
Imbalanced base excision repair in response to folate deficiency is accelerated by polymerase beta haploinsufficiency.
Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repair.
X-ray repair cross-complementing gene I protein plays an important role in camptothecin resistance.
Elevated levels of oxidative DNA damage and DNA repair enzymes in human atherosclerotic plaques.
Oxidative DNA damage and repair in experimental atherosclerosis are reversed by dietary lipid lowering.
Oxidative DNA damage and repair in experimental atherosclerosis are reversed by dietary lipid lowering.
Bigarella CL, Li J, Rimmelé P, Liang R, Sobol RW, Ghaffari S
The Journal of biological chemistry 2017 Feb 17;292(7):3005-3015
The Journal of biological chemistry 2017 Feb 17;292(7):3005-3015
HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β.
Fang Q, Inanc B, Schamus S, Wang XH, Wei L, Brown AR, Svilar D, Sugrue KF, Goellner EM, Zeng X, Yates NA, Lan L, Vens C, Sobol RW
Nature communications 2014 Nov 26;5:5513
Nature communications 2014 Nov 26;5:5513
Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice.
Unnikrishnan A, Raffoul JJ, Patel HV, Prychitko TM, Anyangwe N, Meira LB, Friedberg EC, Cabelof DC, Heydari AR
Free radical biology & medicine 2009 Jun 1;46(11):1488-99
Free radical biology & medicine 2009 Jun 1;46(11):1488-99
Molecular characterization of spontaneous mesenchymal stem cell transformation.
Rubio D, Garcia S, Paz MF, De la Cueva T, Lopez-Fernandez LA, Lloyd AC, Garcia-Castro J, Bernad A
PloS one 2008 Jan 2;3(1):e1398
PloS one 2008 Jan 2;3(1):e1398
Methylation of DNA polymerase beta by protein arginine methyltransferase 1 regulates its binding to proliferating cell nuclear antigen.
El-Andaloussi N, Valovka T, Toueille M, Hassa PO, Gehrig P, Covic M, Hübscher U, Hottiger MO
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007 Jan;21(1):26-34
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007 Jan;21(1):26-34
Possible role of DNA polymerase beta in protecting human bronchial epithelial cells against cytotoxicity of hydroquinone.
Hu DL, Tang HW, Liang HR, Tang DS, Liu YM, Ji WD, Yuan JH, He Y, Zhu ZY, Yang JP, Fang DK, Sha Y, Tu XZ, Zhuang ZX
Biomedical and environmental sciences : BES 2007 Apr;20(2):171-7
Biomedical and environmental sciences : BES 2007 Apr;20(2):171-7
Connexin-specific cell-to-cell transfer of short interfering RNA by gap junctions.
Valiunas V, Polosina YY, Miller H, Potapova IA, Valiuniene L, Doronin S, Mathias RT, Robinson RB, Rosen MR, Cohen IS, Brink PR
The Journal of physiology 2005 Oct 15;568(Pt 2):459-68
The Journal of physiology 2005 Oct 15;568(Pt 2):459-68
The overexpression of specialized DNA polymerases in cancer.
Albertella MR, Lau A, O'Connor MJ
DNA repair 2005 May 2;4(5):583-93
DNA repair 2005 May 2;4(5):583-93
A new XRCC1-containing complex and its role in cellular survival of methyl methanesulfonate treatment.
Luo H, Chan DW, Yang T, Rodriguez M, Chen BP, Leng M, Mu JJ, Chen D, Songyang Z, Wang Y, Qin J
Molecular and cellular biology 2004 Oct;24(19):8356-65
Molecular and cellular biology 2004 Oct;24(19):8356-65
Human and rodent cell lines showing no differences in the induction but differing in the repair kinetics of radiation-induced DNA base damage.
Purschke M, Kasten-Pisula U, Brammer I, Dikomey E
International journal of radiation biology 2004 Jan;80(1):29-38
International journal of radiation biology 2004 Jan;80(1):29-38
Imbalanced base excision repair in response to folate deficiency is accelerated by polymerase beta haploinsufficiency.
Cabelof DC, Raffoul JJ, Nakamura J, Kapoor D, Abdalla H, Heydari AR
The Journal of biological chemistry 2004 Aug 27;279(35):36504-13
The Journal of biological chemistry 2004 Aug 27;279(35):36504-13
Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repair.
Raffoul JJ, Cabelof DC, Nakamura J, Meira LB, Friedberg EC, Heydari AR
The Journal of biological chemistry 2004 Apr 30;279(18):18425-33
The Journal of biological chemistry 2004 Apr 30;279(18):18425-33
X-ray repair cross-complementing gene I protein plays an important role in camptothecin resistance.
Park SY, Lam W, Cheng YC
Cancer research 2002 Jan 15;62(2):459-65
Cancer research 2002 Jan 15;62(2):459-65
Elevated levels of oxidative DNA damage and DNA repair enzymes in human atherosclerotic plaques.
Martinet W, Knaapen MW, De Meyer GR, Herman AG, Kockx MM
Circulation 2002 Aug 20;106(8):927-32
Circulation 2002 Aug 20;106(8):927-32
Oxidative DNA damage and repair in experimental atherosclerosis are reversed by dietary lipid lowering.
Martinet W, Knaapen MW, De Meyer GR, Herman AG, Kockx MM
Circulation research 2001 Apr 13;88(7):733-9
Circulation research 2001 Apr 13;88(7):733-9
Oxidative DNA damage and repair in experimental atherosclerosis are reversed by dietary lipid lowering.
Martinet W, Knaapen MW, De Meyer GR, Herman AG, Kockx MM
Circulation research 2001 Apr 13;88(7):733-9
Circulation research 2001 Apr 13;88(7):733-9
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot of Rat DNA Polymerase beta using Rat DNA Polymerase beta Monoclonal Antibody (Product # MA5-13899) on HeLa Cells.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunoprecipitation of Rat DNA Polymerase beta using Rat DNA Polymerase beta Monoclonal Antibody (Product # MA5-13899) on denatured Mouse MAD109 Cells.
