Antibody data
- Antibody Data
- Antigen structure
- References [23]
- Comments [0]
- Validations [0]
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- Product number
- 14266-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14266-1-AP, RRID:AB_2636822
- Product name
- ADRA2A antibody
- Antibody type
- Polyclonal
- Description
- ADRA2A antibody (Cat. #14266-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Sympathetic nerve aggravates autoimmune skin disease via NE-adrenergic receptor axis: Neuroimmune cross-talk insights from vitiligo.
Multi-timescale Computation by Astrocytes.
Necl1 deficiency induces noradrenergic dysfunction and depressive-like states in rodents: A cross-species model validated by pharmacological intervention.
Neuronal Subtype-Specific Expression of γ-Enolase: Its Role in Neuronal Differentiation.
Electroacupuncture at ST25 ameliorated gastrointestinal dysmotility via downregulation sympathetic nerve-mediated α2-adrenoceptors in postoperative ileus.
The Discovery of α-Adrenoceptor Antagonists as a Potential New Treatment Option for Uveal Melanoma.
Bipolar and schizophrenia risk gene AKAP11 encodes an autophagy receptor coupling the regulation of PKA kinase network homeostasis to synaptic transmission.
ADRA2A contributes to airway inflammation and apoptosis in asthma through the ERK signaling in vitro and in vivo.
Bipolar and schizophrenia risk gene AKAP11 encodes an autophagy receptor coupling the regulation of PKA kinase network homeostasis to synaptic transmission.
Clonidine mitigates noise-induced hearing loss by regulating TRPC6-mediated calcium influx in cochlear hair cells.
Norepinephrine protects against cochlear outer hair cell damage and noise-induced hearing loss via α(2A)-adrenergic receptor.
Dexmedetomidine facilitates autophagic flux to promote liver regeneration by suppressing GSK3β activity in mouse partial hepatectomy.
Chemoproteomics reveals microbiota-derived aromatic monoamine agonists for GPRC5A.
SNHG15, a p53-regulated lncRNA, suppresses cisplatin-induced apoptosis and ROS accumulation through the miR-335-3p/ZNF32 axis.
Two-hour acute restraint stress facilitates escape behavior and learning outcomes through the activation of the Cdk5/GR P S211 pathway in male mice.
β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis.
Local activation of α2 adrenergic receptors is required for vagus nerve stimulation induced motor cortical plasticity.
The α2AR/Caveolin-1/p38MAPK/NF-κB axis explains dexmedetomidine protection against lung injury following intestinal ischaemia-reperfusion.
Chronic Administrations of Guanfacine on Mesocortical Catecholaminergic and Thalamocortical Glutamatergic Transmissions.
Sympathetic innervation contributes to perineural invasion of salivary adenoid cystic carcinoma via the β2-adrenergic receptor.
Effects of α2A Adrenoceptors on Norepinephrine Secretion from the Locus Coeruleus during Chronic Stress-Induced Depression.
Cingulate Alpha-2A Adrenoceptors Mediate the Effects of Clonidine on Spontaneous Pain Induced by Peripheral Nerve Injury.
Transcription Factor CREM Mediates High Glucose Response in Cardiomyocytes and in a Male Mouse Model of Prolonged Hyperglycemia.
Huang L, Kang P, Chen J, Sun W, Yin H, Yang Y, Guo S, Yi X, Chen J, Li S, Li C
Science advances 2026 Mar 6;12(10):eaea7017
Science advances 2026 Mar 6;12(10):eaea7017
Multi-timescale Computation by Astrocytes.
Li C, Gong L, Song C, Ching S, Pozzo-Miller L, Li W
bioRxiv : the preprint server for biology 2026 Mar 18;
bioRxiv : the preprint server for biology 2026 Mar 18;
Necl1 deficiency induces noradrenergic dysfunction and depressive-like states in rodents: A cross-species model validated by pharmacological intervention.
Song J, Wang L, Suo J, Ran K, Han W, Peng X
Journal of affective disorders 2026 Mar 1;396:120776
Journal of affective disorders 2026 Mar 1;396:120776
Neuronal Subtype-Specific Expression of γ-Enolase: Its Role in Neuronal Differentiation.
Horvat S, Pečar Fonović U, Zidar N, Doljak B, Kos J, Pišlar A
Neuromolecular medicine 2026 Jan 30;28(1):4
Neuromolecular medicine 2026 Jan 30;28(1):4
Electroacupuncture at ST25 ameliorated gastrointestinal dysmotility via downregulation sympathetic nerve-mediated α2-adrenoceptors in postoperative ileus.
Liu YD, Li YJ, Huang J, Yang JW, Liu CZ, Shi GX, Yang NN
American journal of physiology. Regulatory, integrative and comparative physiology 2025 Sep 1;329(3):R495-R505
American journal of physiology. Regulatory, integrative and comparative physiology 2025 Sep 1;329(3):R495-R505
The Discovery of α-Adrenoceptor Antagonists as a Potential New Treatment Option for Uveal Melanoma.
He Y, Liu H, Hendgen-Cotta U, Rassaf T, Bechrakis NE, Berchner-Pfannschmidt U
Biomolecules 2025 Oct 10;15(10)
Biomolecules 2025 Oct 10;15(10)
Bipolar and schizophrenia risk gene AKAP11 encodes an autophagy receptor coupling the regulation of PKA kinase network homeostasis to synaptic transmission.
Lee YK, Xiao C, Zhou X, Wang L, McReynolds M, Wu Z, Han X, Purisic E, Kim H, Li X, Pang Z, Dai J, Peng J, Yang N, Yue Z
Nature communications 2025 Nov 28;16(1):10792
Nature communications 2025 Nov 28;16(1):10792
ADRA2A contributes to airway inflammation and apoptosis in asthma through the ERK signaling in vitro and in vivo.
Zhou F, Cai J, Chen L, Tan X, Li C
Journal of inflammation (London, England) 2025 Nov 26;22(1):55
Journal of inflammation (London, England) 2025 Nov 26;22(1):55
Bipolar and schizophrenia risk gene AKAP11 encodes an autophagy receptor coupling the regulation of PKA kinase network homeostasis to synaptic transmission.
Lee YK, Xiao C, Zhou X, Wang L, McReynolds MG, Wu Z, Purisic E, Kim H, Li X, Pang Z, Dai J, Peng J, Yang N, Yue Z
Research square 2025 Mar 13;
Research square 2025 Mar 13;
Clonidine mitigates noise-induced hearing loss by regulating TRPC6-mediated calcium influx in cochlear hair cells.
Zhai W, Kuang X, Wu J, Li L, Li B, Geng R, Zheng T, Zheng Q
Hearing research 2025 Jun;462:109284
Hearing research 2025 Jun;462:109284
Norepinephrine protects against cochlear outer hair cell damage and noise-induced hearing loss via α(2A)-adrenergic receptor.
Tian C, Yang Y, Wang R, Li Y, Sun F, Chen J, Zha D
BMC neuroscience 2024 Jan 30;25(1):5
BMC neuroscience 2024 Jan 30;25(1):5
Dexmedetomidine facilitates autophagic flux to promote liver regeneration by suppressing GSK3β activity in mouse partial hepatectomy.
Yao X, Liu Y, Sui Y, Zheng M, Zhu L, Li Q, Irwin MG, Yang L, Zhan Q, Xiao J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117038
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117038
Chemoproteomics reveals microbiota-derived aromatic monoamine agonists for GPRC5A.
Zhao X, Stein KR, Chen V, Griffin ME, Lairson LL, Hang HC
Nature chemical biology 2023 Oct;19(10):1205-1214
Nature chemical biology 2023 Oct;19(10):1205-1214
SNHG15, a p53-regulated lncRNA, suppresses cisplatin-induced apoptosis and ROS accumulation through the miR-335-3p/ZNF32 axis.
Sun YF, Wang Y, Li XD, Wang H
American journal of cancer research 2022;12(2):816-828
American journal of cancer research 2022;12(2):816-828
Two-hour acute restraint stress facilitates escape behavior and learning outcomes through the activation of the Cdk5/GR P S211 pathway in male mice.
Wang B, Yang X, Lu J, Ntim M, Xia M, Kundu S, Jiang R, Chen D, Wang Y, Yang JY, Li S
Experimental neurology 2022 Aug;354:114023
Experimental neurology 2022 Aug;354:114023
β2-Adrenoceptor Deficiency Results in Increased Calcified Cartilage Thickness and Subchondral Bone Remodeling in Murine Experimental Osteoarthritis.
Rösch G, Muschter D, Taheri S, El Bagdadi K, Dorn C, Meurer A, Zaucke F, Schilling AF, Grässel S, Straub RH, Jenei-Lanzl Z
Frontiers in immunology 2021;12:801505
Frontiers in immunology 2021;12:801505
Local activation of α2 adrenergic receptors is required for vagus nerve stimulation induced motor cortical plasticity.
Tseng CT, Gaulding SJ, Dancel CLE, Thorn CA
Scientific reports 2021 Nov 4;11(1):21645
Scientific reports 2021 Nov 4;11(1):21645
The α2AR/Caveolin-1/p38MAPK/NF-κB axis explains dexmedetomidine protection against lung injury following intestinal ischaemia-reperfusion.
Xu L, Li T, Chen Q, Liu Z, Chen Y, Hu K, Zhang X
Journal of cellular and molecular medicine 2021 Jun 10;25(13):6361-72
Journal of cellular and molecular medicine 2021 Jun 10;25(13):6361-72
Chronic Administrations of Guanfacine on Mesocortical Catecholaminergic and Thalamocortical Glutamatergic Transmissions.
Fukuyama K, Nakano T, Shiroyama T, Okada M
International journal of molecular sciences 2021 Apr 16;22(8)
International journal of molecular sciences 2021 Apr 16;22(8)
Sympathetic innervation contributes to perineural invasion of salivary adenoid cystic carcinoma via the β2-adrenergic receptor.
Ma C, Gao T, Ju J, Zhang Y, Ni Q, Li Y, Zhao Z, Chai J, Yang X, Sun M
OncoTargets and therapy 2019;12:1475-1495
OncoTargets and therapy 2019;12:1475-1495
Effects of α2A Adrenoceptors on Norepinephrine Secretion from the Locus Coeruleus during Chronic Stress-Induced Depression.
Wang B, Wang Y, Wu Q, Huang HP, Li S
Frontiers in neuroscience 2017;11:243
Frontiers in neuroscience 2017;11:243
Cingulate Alpha-2A Adrenoceptors Mediate the Effects of Clonidine on Spontaneous Pain Induced by Peripheral Nerve Injury.
Wang YJ, Zuo ZX, Wu C, Liu L, Feng ZH, Li XY
Frontiers in molecular neuroscience 2017;10:289
Frontiers in molecular neuroscience 2017;10:289
Transcription Factor CREM Mediates High Glucose Response in Cardiomyocytes and in a Male Mouse Model of Prolonged Hyperglycemia.
Barbati SA, Colussi C, Bacci L, Aiello A, Re A, Stigliano E, Isidori AM, Grassi C, Pontecorvi A, Farsetti A, Gaetano C, Nanni S
Endocrinology 2017 Jul 1;158(7):2391-2405
Endocrinology 2017 Jul 1;158(7):2391-2405
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