APR06918G

IZUMO1 antibody from Leading Biology
IZUMO, MGC34799, OBF
Western blot
Recommended by provider
Immunohistochemistry
Recommended by provider

Antibody data

Product number
APR06918G
Provider
Leading Biology
Product name
IZUMO1 Antibody
Provider product page
Leading Biology - APR06918G
Antibody type
Polyclonal
Description
IZUMO1, a sperm-specific protein, is essential for sperm-egg plasma membrane binding and fusion. It is involved in the fertilization process and in the fusion of the sperm with the egg (1,2). IZUMO1 is expressed as at least four isoforms produced by alternative splicing and contains one Ig-like (immunoglobulin-like) C2-type domain (3). Lack of IZUMO1 in males, due to homozygous mutation in the gene that encodes IZUMO1, results in sterility due to an inability to penetrate the plasma membrane of the egg (4).
Reactivity
Human
Host
Rabbit
Isotype
IgG
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.