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IZUMO1 antibody from Leading Biology
IZUMO, MGC34799, OBF
- Western blot
Recommended by provider
- Immunohistochemistry
- Recommended by provider
Antibody data
- Antibody Data
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- Product number
- APR06918G
- Provider
- Leading Biology
- Product name
- IZUMO1 Antibody
- Provider product page
- Leading Biology - APR06918G
- Antibody type
- Polyclonal
- Description
- IZUMO1, a sperm-specific protein, is essential for sperm-egg plasma membrane binding and fusion. It is involved in the fertilization process and in the fusion of the sperm with the egg (1,2). IZUMO1 is expressed as at least four isoforms produced by alternative splicing and contains one Ig-like (immunoglobulin-like) C2-type domain (3). Lack of IZUMO1 in males, due to homozygous mutation in the gene that encodes IZUMO1, results in sterility due to an inability to penetrate the plasma membrane of the egg (4).
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.