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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [9]
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- Validations
- Western blot [1]
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- Product number
- NB500-176 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB500-176, RRID:AB_10000829
- Product name
- Rabbit Polyclonal POT1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 2.25 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references Telomere protein RAP1 levels are affected by cellular aging and oxidative stress.
Telomeres and Telomerase in the Radiation Response: Implications for Instability, Reprograming, and Carcinogenesis.
Bortezomib-mediated down-regulation of telomerase and disruption of telomere homeostasis contributes to apoptosis of malignant cells.
Mir-23a induces telomere dysfunction and cellular senescence by inhibiting TRF2 expression.
T-oligo as an anticancer agent in colorectal cancer.
Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response.
Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein-Barr virus.
Functional diversity of human protection of telomeres 1 isoforms in telomere protection and cellular senescence.
Telomere maintenance through spatial control of telomeric proteins.
Swanson MJ, Baribault ME, Israel JN, Bae NS
Biomedical reports 2016 Aug;5(2):181-187
Biomedical reports 2016 Aug;5(2):181-187
Telomeres and Telomerase in the Radiation Response: Implications for Instability, Reprograming, and Carcinogenesis.
Sishc BJ, Nelson CB, McKenna MJ, Battaglia CL, Herndon A, Idate R, Liber HL, Bailey SM
Frontiers in oncology 2015;5:257
Frontiers in oncology 2015;5:257
Bortezomib-mediated down-regulation of telomerase and disruption of telomere homeostasis contributes to apoptosis of malignant cells.
Ci X, Li B, Ma X, Kong F, Zheng C, Björkholm M, Jia J, Xu D
Oncotarget 2015 Nov 10;6(35):38079-92
Oncotarget 2015 Nov 10;6(35):38079-92
Mir-23a induces telomere dysfunction and cellular senescence by inhibiting TRF2 expression.
Luo Z, Feng X, Wang H, Xu W, Zhao Y, Ma W, Jiang S, Liu D, Huang J, Songyang Z
Aging cell 2015 Jun;14(3):391-9
Aging cell 2015 Jun;14(3):391-9
T-oligo as an anticancer agent in colorectal cancer.
Wojdyla L, Stone AL, Sethakorn N, Uppada SB, Devito JT, Bissonnette M, Puri N
Biochemical and biophysical research communications 2014 Apr 4;446(2):596-601
Biochemical and biophysical research communications 2014 Apr 4;446(2):596-601
Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response.
Jullien L, Mestre M, Roux P, Gire V
Nucleic acids research 2013 Jan;41(2):900-11
Nucleic acids research 2013 Jan;41(2):900-11
Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein-Barr virus.
Kamranvar SA, Chen X, Masucci MG
Oncogene 2013 Dec 5;32(49):5522-30
Oncogene 2013 Dec 5;32(49):5522-30
Functional diversity of human protection of telomeres 1 isoforms in telomere protection and cellular senescence.
Yang Q, Zhang R, Horikawa I, Fujita K, Afshar Y, Kokko A, Laiho P, Aaltonen LA, Harris CC
Cancer research 2007 Dec 15;67(24):11677-86
Cancer research 2007 Dec 15;67(24):11677-86
Telomere maintenance through spatial control of telomeric proteins.
Chen LY, Liu D, Songyang Z
Molecular and cellular biology 2007 Aug;27(16):5898-909
Molecular and cellular biology 2007 Aug;27(16):5898-909
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: POT1 Antibody [NB500-176] - Detection of POT1 in HeLa nuclear extracts (25 ug) using NB500-176(1:500). ECL detection 1 min.
