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- Product number
- ABIN2838017 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (N-Term) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Epitope
- N-Term
- Isotype
- IgG
- Antibody clone number
- 43AT551-86
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots.
- Handling
- Avoid freeze-thaw cycles.
Submitted references An miR-502-binding site single-nucleotide polymorphism in the 3'-untranslated region of the SET8 gene is associated with early age of breast cancer onset.
SET8 plays a role in controlling G1/S transition by blocking lysine acetylation in histone through binding to H4 N-terminal tail.
Product specificity and mechanism of protein lysine methyltransferases: insights from the histone lysine methyltransferase SET8.
PR-Set7 establishes a repressive trans-tail histone code that regulates differentiation.
Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stability.
Song F, Zheng H, Liu B, Wei S, Dai H, Zhang L, Calin GA, Hao X, Wei Q, Zhang W, Chen K
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Oct 1;15(19):6292-300
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Oct 1;15(19):6292-300
SET8 plays a role in controlling G1/S transition by blocking lysine acetylation in histone through binding to H4 N-terminal tail.
Yin Y, Yu VC, Zhu G, Chang DC
Cell cycle (Georgetown, Tex.) 2008 May 15;7(10):1423-32
Cell cycle (Georgetown, Tex.) 2008 May 15;7(10):1423-32
Product specificity and mechanism of protein lysine methyltransferases: insights from the histone lysine methyltransferase SET8.
Zhang X, Bruice TC
Biochemistry 2008 Jun 24;47(25):6671-7
Biochemistry 2008 Jun 24;47(25):6671-7
PR-Set7 establishes a repressive trans-tail histone code that regulates differentiation.
Sims JK, Rice JC
Molecular and cellular biology 2008 Jul;28(14):4459-68
Molecular and cellular biology 2008 Jul;28(14):4459-68
Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stability.
Houston SI, McManus KJ, Adams MM, Sims JK, Carpenter PB, Hendzel MJ, Rice JC
The Journal of biological chemistry 2008 Jul 11;283(28):19478-88
The Journal of biological chemistry 2008 Jul 11;283(28):19478-88
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
