PA5-21549

antibody from Invitrogen Antibodies

Targeting: BCAT2 BCAM, BCT2

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

PA5-21549

Provider

Invitrogen Antibodies

Product name

BCAT2 Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Recombinant protein fragment

Description

Recommended positive controls: BCAT2-transfected 293T. Predicted reactivity: Mouse (85%), Rat (83%), Bovine (87%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100 µL

Concentration

0.19 mg/mL

Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

References

Submitted references

Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression.

Ericksen RE, Lim SL, McDonnell E, Shuen WH, Vadiveloo M, White PJ, Ding Z, Kwok R, Lee P, Radda GK, Toh HC, Hirschey MD, Han W
Cell metabolism 2019 May 7;29(5):1151-1165.e6

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Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure.

Uddin GM, Zhang L, Shah S, Fukushima A, Wagg CS, Gopal K, Al Batran R, Pherwani S, Ho KL, Boisvenue J, Karwi QG, Altamimi T, Wishart DS, Dyck JRB, Ussher JR, Oudit GY, Lopaschuk GD
Cardiovascular diabetology 2019 Jul 5;18(1):86

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Cardiac branched-chain amino acid oxidation is reduced during insulin resistance in the heart.

Fillmore N, Wagg CS, Zhang L, Fukushima A, Lopaschuk GD
American journal of physiology. Endocrinology and metabolism 2018 Nov 1;315(5):E1046-E1052