Antibody data
- Antibody Data
- Antigen structure
- References [144]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
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- Product number
- 12129-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12129-1-AP, RRID:AB_2191889
- Product name
- SNAI2 antibody
- Antibody type
- Polyclonal
- Description
- SNAI2 antibody (Cat. #12129-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hypoxia-driven TNS4 fosters HNSCC tumorigenesis by stabilizing integrin α5β1 complex and triggering FAK-mediated Akt and TGFβ signaling pathways.
The anti-tumor activity of tangeretin in esophageal squamous cell carcinoma by inhibiting GLI2-mediated transcription of GPNMB.
Daurisoline suppress glioma progression by inhibiting autophagy through PI3K/AKT/mTOR pathway and increases TMZ sensitivity.
N6-methyladenosine-modified CircPSMA7 enhances bladder cancer malignancy through the miR-128-3p/MAPK1 axis.
IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development.
SNAI2/FTH1P3/miR-218-5p Positive Feedback Loop Promotes Colorectal Cancer Metastasis.
Silencing of cysteine and serine rich nuclear protein 1 inhibits apoptosis, senescence and collagen degradation in human-derived vaginal fibroblasts in response to oxidative stress or DNA damage.
HIF-1A as a prognostic biomarker related to invasion, migration and immunosuppression of cervical cancer.
Dexmedetomidine ameliorates high glucose-induced epithelial-mesenchymal transformation in HK-2 cells through the Cdk5/Drp1/ROS pathway.
Activation of IGFBP4 via unconventional mechanism of miRNA attenuates metastasis of intrahepatic cholangiocarcinoma.
LINC02561 promotes metastasis in HCC via HIF1-α/NDRG1/UPF1 axis.
FERMT2 upregulation in CAFs enhances EMT of OSCC and M2 macrophage polarization.
A pyrazolopyridine as a novel AhR signaling activator with anti-breast cancer properties in vitro and in vivo.
Adhesive hydrogel releases protocatechualdehyde-Fe(3+) complex to promote three healing stages for accelerated therapy of oral ulcers.
LIM Homeobox 2 Increases Adhesion-Regulating Molecule 1 Transcription to Facilitate the Pathological Progression of Oxidized Low-Density Lipoprotein-Stimulated Atherosclerotic Cell Models.
Timosaponin AIII promotes non-small-cell lung cancer ferroptosis through targeting and facilitating HSP90 mediated GPX4 ubiquitination and degradation.
Aquaporin 9 is involved in CRC metastasis through DVL2-dependent Wnt/β-catenin signaling activation.
Pan-cancer integrated bioinformatic analysis of RNA polymerase subunits reveal RNA Pol I member CD3EAP regulates cell growth by modulating autophagy.
SPI1-Mediated Upregulation of the CST1 Gene as an Independent Poor Prognostic Factor Accelerates Metastasis in Esophageal Squamous Cell Carcinoma (ESCC) by Interacting with MMP2.
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
Hsa_circ_0001535 inhibits the proliferation and migration of ovarian cancer by sponging miR-593-3p, upregulating PTEN expression.
Fucoidan/chitosan layered PLGA nanoparticles with melatonin loading for inducing intestinal absorption and addressing triple-negative breast cancer progression.
Exploring the anticancer potential of Actinidia chinensis Planch root extracts (acRoots) on hepatocellular carcinoma: A molecular mechanism study.
Lnc AC016727.1/BACH1/HIF-1 α signal loop promotes the progression of non-small cell lung cancer.
Intracellular FGF1 promotes invasion and migration in thyroid carcinoma via HMGA1 independent of FGF receptors.
N4-acetylcytidine modification of lncRNA CTC-490G23.2 promotes cancer metastasis through interacting with PTBP1 to increase CD44 alternative splicing.
Immunity-related long noncoding RNA WDFY3-AS2 inhibited cell proliferation and metastasis through Wnt/β-catenin signaling in oral squamous cell carcinoma.
NONHSAT021545/miR-330-3p/EREG: A Cooperative Axis in Breast Cancer Prognosis and Treatment.
EGR1 induces EMT in pancreatic cancer via a P300/SNAI2 pathway.
Inhibition of IDH3α Enhanced the Efficacy of Chemoimmunotherapy by Regulating Acidic Tumor Microenvironments.
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.
Downregulation of CYRI-B promotes migration, invasion and EMT by activating the Rac1-STAT3 pathway in gastric cancer.
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells.
Histone demethylase KDM4B accelerates the progression of glioblastoma via the epigenetic regulation of MYC stability.
Combined effects of vitamin D and neferine on the progression and metastasis of colorectal cancer.
PRSS2 regulates EMT and metastasis via MMP-9 in gastric cancer.
Comprehensive bioinformatics and experimental analysis of SH3PXD2B reveals its carcinogenic effect in gastric carcinoma.
ZSWIM1 Promotes the Proliferation and Metastasis of Lung Adenocarcinoma Cells through the STK38/MEKK2/ERK1/2 Axis.
Multifunctional Drug-Loaded Phase-Change Nanoparticles Inhibit the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma by Affecting the Activity of Activated Hepatic Stellate Cells.
CD44v6+ Hepatocellular Carcinoma Cells Maintain Stemness Properties through Met/cJun/Nanog Signaling.
Smurf2 suppresses the metastasis of hepatocellular carcinoma via ubiquitin degradation of Smad2.
The homeostatic malfunction of a novel feedback pathway formed by lncRNA021545, miR-330-3p and epiregulin contributes in hepatocarcinoma progression via mediating epithelial-mesenchymal transition.
Interleukin-17 promotes the development of ovarian cancer through upregulation of MTA1 expression.
Neutrophils Promote Tumor Progression in Oral Squamous Cell Carcinoma by Regulating EMT and JAK2/STAT3 Signaling Through Chemerin.
IQGAP3 in clear cell renal cell carcinoma contributes to drug resistance and genome stability.
ATP11A promotes EMT by regulating Numb PRR(L) in pancreatic cancer cells.
An epithelial-mesenchymal plasticity signature identifies two novel LncRNAs with the opposite regulation.
Targeting MALT1 Suppresses the Malignant Progression of Colorectal Cancer via miR-375/miR-365a-3p/NF-κB Axis.
Exosomal miR-22-3p from Mesenchymal Stem Cells Inhibits the Epithelial-Mesenchymal Transition (EMT) of Melanoma Cells by Regulating LGALS1.
3-Nitrobenzanthrone promotes malignant transformation in human lung epithelial cells through the epiregulin-signaling pathway.
ALG3 Promotes Peritoneal Metastasis of Ovarian Cancer through Increasing Interaction of α1,3-mannosylated uPAR and ADAM8.
Cerulenin suppresses ErbB2-overexpressing breast cancer by targeting ErbB2/PKM2 pathway.
CHRNB2 represses pancreatic cancer migration and invasion via inhibiting β-catenin pathway.
Circular RNA hsa_circ_0051040 Promotes Hepatocellular Carcinoma Progression by Sponging miR-569 and Regulating ITGAV Expression.
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Downregulation of estrogen receptor-α36 expression attenuates metastasis of hepatocellular carcinoma cells.
miR-217-5p suppresses epithelial-mesenchymal transition and the NF-κB signaling pathway in breast cancer via targeting of metadherin.
Exosomal MMP-1 transfers metastasis potential in triple-negative breast cancer through PAR1-mediated EMT.
The miR-214-3p/c-Ski axis modulates endothelial-mesenchymal transition in human coronary artery endothelial cells in vitro and in mice model in vivo.
Inhibition of translocator protein 18 kDa suppressed the progression of glioma via the ELAV-like RNA-binding protein 1/MAPK-activated protein kinase 3 axis.
Chelerythrine inhibits the progression of glioblastoma by suppressing the TGFB1-ERK1/2/Smad2/3-Snail/ZEB1 signaling pathway.
Crumbs3 is expressed in oral squamous cell carcinomas and promotes cell migration and proliferation by affecting RhoA activity.
LncRNA BACE1-AS promotes the progression of osteosarcoma through miR-762/SOX7 axis.
Overexpression of ERCC6L correlates with poor prognosis and confers malignant phenotypes of lung adenocarcinoma.
Copper ionophore elesclomol selectively targets GNAQ/11-mutant uveal melanoma.
ZC3H15 promotes glioblastoma progression through regulating EGFR stability.
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Numb-PRRL promotes TGF-β1- and EGF-induced epithelial-to-mesenchymal transition in pancreatic cancer.
USF1-CHCHD4 axis promotes lung adenocarcinoma progression partially via activating the MYC pathway.
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
A multifunctional black phosphorus-based adhesive patch intrinsically induces partial EMT for effective burn wound healing.
LncRNA ELF3-AS1 inhibits gastric cancer by forming a negative feedback loop with SNAI2 and regulates ELF3 mRNA stability via interacting with ILF2/ILF3 complex.
SEC14L3 plays a tumor-suppressive role in breast cancer through a Wnt/β-catenin-related way.
Bolbostemma paniculatum (Maxim.) Franquet extract suppresses the development of colorectal cancer through downregulation of PI3K/Akt pathway.
Mitochondrial calcium uptake regulates tumour progression in embryonal rhabdomyosarcoma.
Epigenetic Deregulation of Protein Tyrosine Kinase 6 Promotes Carcinogenesis of Oral Squamous Cell Carcinoma.
Polydatin Inhibits Cell Viability, Migration, and Invasion Through Suppressing the c-Myc Expression in Human Cervical Cancer.
MRPL13 Promotes Tumor Cell Proliferation, Migration and EMT Process in Breast Cancer Through the PI3K-AKT-mTOR Pathway.
JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation.
Linc01513 inhibits the malignant potential of Nasopharyngeal carcinoma by binding to PTBP1.
Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development.
TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.
MIER3 induces epithelial-mesenchymal transition and promotes breast cancer cell aggressiveness via forming a co-repressor complex with HDAC1/HDAC2/Snail.
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
NOTCH2NLA silencing inhibits ovarian carcinoma progression and oncogenic activity in vivo and in vitro.
The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.
Effects of Cynaroside on Cell Proliferation, Apoptosis, Migration and Invasion though the MET/AKT/mTOR Axis in Gastric Cancer.
Inhibition of DEC2 is necessary for exiting cell dormancy in salivary adenoid cystic carcinoma.
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.
Overexpression of NCAPG inhibits cardia adenocarcinoma apoptosis and promotes epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway.
Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/β-catenin/PPARδ signalling.
Inhibitory role of ATF3 in gastric cancer progression through regulating cell EMT and stemness.
FOXD1 promotes EMT and cell stemness of oral squamous cell carcinoma by transcriptional activation of SNAI2.
Neuron specific enolase promotes tumor metastasis by activating the Wnt/β-catenin pathway in small cell lung cancer.
Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer.
Fibroblast Activation Protein (FAP) Overexpression Induces Epithelial-Mesenchymal Transition (EMT) in Oral Squamous Cell Carcinoma by Down-Regulating Dipeptidyl Peptidase 9 (DPP9).
Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells.
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.
IMPDH1/YB-1 Positive Feedback Loop Assembles Cytoophidia and Represents a Therapeutic Target in Metastatic Tumors.
IGF-1 promotes multiple myeloma progression through PI3K/Akt-mediated epithelial-mesenchymal transition.
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.
SP1-activated long noncoding RNA lncRNA GCMA functions as a competing endogenous RNA to promote tumor metastasis by sponging miR-124 and miR-34a in gastric cancer.
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
Long noncoding RNA MAPKAPK5-AS1 promotes colorectal cancer progression by cis-regulating the nearby gene MK5 and acting as a let-7f-1-3p sponge.
CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling.
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Graphene Oxide Promotes Cancer Metastasis through Associating with Plasma Membrane To Promote TGF-β Signaling-Dependent Epithelial-Mesenchymal Transition.
Aberrant methylation‑mediated decrease of lncRNA HNF1A‑AS1 contributes to malignant progression of laryngeal squamous cell carcinoma via EMT.
Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Nr5a2 promotes tumor growth and metastasis of gastric cancer AGS cells by Wnt/beta-catenin signaling.
Lipase member H is a downstream molecular target of hypoxia inducible factor-1α and promotes papillary thyroid carcinoma cell migration in BCPAP and KTC-1 cell lines.
CD36 promotes the epithelial-mesenchymal transition and metastasis in cervical cancer by interacting with TGF-β.
α-Aminoisobutyric Acid-Containing Amphipathic Helical Peptide-Cyclic RGD Conjugation as a Potential Drug Delivery System for MicroRNA Replacement Therapy in Vitro.
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
M2 macrophages promote NSCLC metastasis by upregulating CRYAB.
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
Prognostic value of multiple epithelial mesenchymal transition-associated proteins in intrahepatic cholangiocarcinoma.
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Cisatracurium Retards Cell Migration and Invasion Upon Upregulation of p53 and Inhibits the Aggressiveness of Colorectal Cancer.
LncRNA UCA1 is necessary for TGF-β-induced epithelial-mesenchymal transition and stemness via acting as a ceRNA for Slug in glioma cells.
The PLGF/c-MYC/miR-19a axis promotes metastasis and stemness in gallbladder cancer.
The long non-coding RNA PTTG3P promotes cell growth and metastasis via up-regulating PTTG1 and activating PI3K/AKT signaling in hepatocellular carcinoma.
Systematic analyses reveal long non-coding RNA (PTAF)-mediated promotion of EMT and invasion-metastasis in serous ovarian cancer.
ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway.
Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis.
UNC0638, a G9a inhibitor, suppresses epithelial‑mesenchymal transition‑mediated cellular migration and invasion in triple negative breast cancer.
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
Long noncoding RNA NEAT1, regulated by LIN28B, promotes cell proliferation and migration through sponging miR-506 in high-grade serous ovarian cancer.
SphK1 modulates cell migration and EMT-related marker expression by regulating the expression of p-FAK in colorectal cancer cells.
Correlations between TBL1XR1 and recurrence of colorectal cancer.
Integrin β4 promotes cell invasion and epithelial-mesenchymal transition through the modulation of Slug expression in hepatocellular carcinoma.
Activation of anaphase-promoting complex by p53 induces a state of dormancy in cancer cells against chemotherapeutic stress.
PFN2, a novel marker of unfavorable prognosis, is a potential therapeutic target involved in esophageal squamous cell carcinoma.
Significance of the NOR1-FOXA1/HDAC2-Slug regulatory network in epithelial-mesenchymal transition of tumor cells.
AEG-1/MTDH-activated autophagy enhances human malignant glioma susceptibility to TGF-β1-triggered epithelial-mesenchymal transition.
Conditional ablation of TGF-β signaling inhibits tumor progression and invasion in an induced mouse bladder cancer model.
Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent ERK signaling.
STK33 plays an important positive role in the development of human large cell lung cancers with variable metastatic potential.
Zhao X, Mai Z, Liu L, Lu Y, Cui L, Yu J
International journal of biological sciences 2024;20(1):231-248
International journal of biological sciences 2024;20(1):231-248
The anti-tumor activity of tangeretin in esophageal squamous cell carcinoma by inhibiting GLI2-mediated transcription of GPNMB.
Yang D, Zhang Q, Kuang H, Liu J, Wu S, Wei L, Yao W
PloS one 2024;19(6):e0291531
PloS one 2024;19(6):e0291531
Daurisoline suppress glioma progression by inhibiting autophagy through PI3K/AKT/mTOR pathway and increases TMZ sensitivity.
Yin HT, Hui-Lu, Yang JH, Li Q, Li M, Zhao QQ, Wen ZP
Biochemical pharmacology 2024 May;223:116113
Biochemical pharmacology 2024 May;223:116113
N6-methyladenosine-modified CircPSMA7 enhances bladder cancer malignancy through the miR-128-3p/MAPK1 axis.
Yi J, Ma X, Ying Y, Liu Z, Tang Y, Shu X, Sun J, Wu Y, Lu D, Wang X, Luo J, Liu B, Zheng X, Lin Y, Li J, Xie L
Cancer letters 2024 Mar 31;585:216613
Cancer letters 2024 Mar 31;585:216613
IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development.
Lv L, Wei Q, Zhang J, Dong Y, Shan Z, Chang N, Zhao Y, Bian P, Yi Q
Cellular & molecular biology letters 2024 Mar 19;29(1):39
Cellular & molecular biology letters 2024 Mar 19;29(1):39
SNAI2/FTH1P3/miR-218-5p Positive Feedback Loop Promotes Colorectal Cancer Metastasis.
Deng H, Zhang Q, Zhao Z, Wang M, Xu Q
Biochemical genetics 2024 Jun;62(3):2210-2223
Biochemical genetics 2024 Jun;62(3):2210-2223
Silencing of cysteine and serine rich nuclear protein 1 inhibits apoptosis, senescence and collagen degradation in human-derived vaginal fibroblasts in response to oxidative stress or DNA damage.
Zhu J, Xu HN, Lin T, Xia ZJ
Experimental cell research 2024 Jul 15;440(2):114139
Experimental cell research 2024 Jul 15;440(2):114139
HIF-1A as a prognostic biomarker related to invasion, migration and immunosuppression of cervical cancer.
Li Z, Wei R, Yao S, Meng F, Kong L
Heliyon 2024 Jan 30;10(2):e24664
Heliyon 2024 Jan 30;10(2):e24664
Dexmedetomidine ameliorates high glucose-induced epithelial-mesenchymal transformation in HK-2 cells through the Cdk5/Drp1/ROS pathway.
Wang F, Xu W, Liu X, Zhang J
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):71-81
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):71-81
Activation of IGFBP4 via unconventional mechanism of miRNA attenuates metastasis of intrahepatic cholangiocarcinoma.
Tao L, Wang Y, Shen Z, Cai J, Zheng J, Xia S, Lin Z, Wan Z, Qi H, Jin R, Wang L, Xu J, Liang X
Hepatology international 2024 Feb;18(1):91-107
Hepatology international 2024 Feb;18(1):91-107
LINC02561 promotes metastasis in HCC via HIF1-α/NDRG1/UPF1 axis.
Li SN, Li MX, Guo WW, Zhang LR, Ding YH, Wu XJ
Gene 2024 Feb 20;896:148033
Gene 2024 Feb 20;896:148033
FERMT2 upregulation in CAFs enhances EMT of OSCC and M2 macrophage polarization.
Ma X, Zhao D, Liu S, Zuo J, Wang W, Wang F, Li Y, Ding Z, Wang J, Wang X
Oral diseases 2024 Apr;30(3):991-1003
Oral diseases 2024 Apr;30(3):991-1003
A pyrazolopyridine as a novel AhR signaling activator with anti-breast cancer properties in vitro and in vivo.
Abduh MS, Alwassil OI, Aldaqal SM, Alfwuaires MA, Farhan M, Hanieh H
Biochemical pharmacology 2024 Apr;222:116079
Biochemical pharmacology 2024 Apr;222:116079
Adhesive hydrogel releases protocatechualdehyde-Fe(3+) complex to promote three healing stages for accelerated therapy of oral ulcers.
Wang Y, Pan Z, Cui J, Zhang X, Li D, Sun H, Yang B, Li Y
Acta biomaterialia 2024 Apr 1;178:68-82
Acta biomaterialia 2024 Apr 1;178:68-82
LIM Homeobox 2 Increases Adhesion-Regulating Molecule 1 Transcription to Facilitate the Pathological Progression of Oxidized Low-Density Lipoprotein-Stimulated Atherosclerotic Cell Models.
Xiao J, Xie Y, Duan Q, Liu T, Ye R, Duan X, Le Z, Deng N, Liu F
International heart journal 2023;64(4):750-758
International heart journal 2023;64(4):750-758
Timosaponin AIII promotes non-small-cell lung cancer ferroptosis through targeting and facilitating HSP90 mediated GPX4 ubiquitination and degradation.
Zhou C, Yu T, Zhu R, Lu J, Ouyang X, Zhang Z, Chen Q, Li J, Cui J, Jiang F, Jin KY, Sarapultsev A, Li F, Zhang G, Luo S, Hu D
International journal of biological sciences 2023;19(5):1471-1489
International journal of biological sciences 2023;19(5):1471-1489
Aquaporin 9 is involved in CRC metastasis through DVL2-dependent Wnt/β-catenin signaling activation.
Liu Y, Gao Q, Feng X, Chen G, Jiang X, Chen D, Yang Z
Gastroenterology report 2023;11:goad033
Gastroenterology report 2023;11:goad033
Pan-cancer integrated bioinformatic analysis of RNA polymerase subunits reveal RNA Pol I member CD3EAP regulates cell growth by modulating autophagy.
Bhandari N, Acharya D, Chatterjee A, Mandve L, Kumar P, Pratap S, Malakar P, Shukla SK
Cell cycle (Georgetown, Tex.) 2023 Sep;22(18):1986-2002
Cell cycle (Georgetown, Tex.) 2023 Sep;22(18):1986-2002
SPI1-Mediated Upregulation of the CST1 Gene as an Independent Poor Prognostic Factor Accelerates Metastasis in Esophageal Squamous Cell Carcinoma (ESCC) by Interacting with MMP2.
Luo FF, Wang J, Zhang ZF, Lin ST, Huang TJ, Liu BQ, Fan ML, Peng LX, Zheng ST, Yang CF, Huang BJ
Frontiers in bioscience (Landmark edition) 2023 Sep 24;28(9):212
Frontiers in bioscience (Landmark edition) 2023 Sep 24;28(9):212
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
Qian X, Zhu L, Xu M, Liu H, Yu X, Shao Q, Qin J
Chemico-biological interactions 2023 Sep 1;382:110588
Chemico-biological interactions 2023 Sep 1;382:110588
Hsa_circ_0001535 inhibits the proliferation and migration of ovarian cancer by sponging miR-593-3p, upregulating PTEN expression.
Han Y, Zheng Y, You J, Han Y, Lu X, Wang X, Shi C, Zhu W
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Oct;25(10):2901-2910
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Oct;25(10):2901-2910
Fucoidan/chitosan layered PLGA nanoparticles with melatonin loading for inducing intestinal absorption and addressing triple-negative breast cancer progression.
Yen YW, Lee YL, Yu LY, Li CE, Shueng PW, Chiu HC, Lo CL
International journal of biological macromolecules 2023 Oct 1;250:126211
International journal of biological macromolecules 2023 Oct 1;250:126211
Exploring the anticancer potential of Actinidia chinensis Planch root extracts (acRoots) on hepatocellular carcinoma: A molecular mechanism study.
Qiu K, Xia Q, Chen H, Ye Q, Mao H, Tian M, Gan Y, Huang Q, Wang H, Duan S
Heliyon 2023 Nov;9(11):e21851
Heliyon 2023 Nov;9(11):e21851
Lnc AC016727.1/BACH1/HIF-1 α signal loop promotes the progression of non-small cell lung cancer.
Zhang L, Liang J, Qin H, Lv Y, Liu X, Li Z, Chao Z, Jia C, Qin X, Zhang H
Journal of experimental & clinical cancer research : CR 2023 Nov 10;42(1):296
Journal of experimental & clinical cancer research : CR 2023 Nov 10;42(1):296
Intracellular FGF1 promotes invasion and migration in thyroid carcinoma via HMGA1 independent of FGF receptors.
Chen Z, Zhong X, Tang W, Xia M, Liu C, Guo Y, Yi Y, Jiang Q, Zu X, Zhong J
Endocrine connections 2023 May 1;12(5)
Endocrine connections 2023 May 1;12(5)
N4-acetylcytidine modification of lncRNA CTC-490G23.2 promotes cancer metastasis through interacting with PTBP1 to increase CD44 alternative splicing.
Yu XM, Li SJ, Yao ZT, Xu JJ, Zheng CC, Liu ZC, Ding PB, Jiang ZL, Wei X, Zhao LP, Shi XY, Li ZG, Xu WW, Li B
Oncogene 2023 Mar;42(14):1101-1116
Oncogene 2023 Mar;42(14):1101-1116
Immunity-related long noncoding RNA WDFY3-AS2 inhibited cell proliferation and metastasis through Wnt/β-catenin signaling in oral squamous cell carcinoma.
Lin X, Ding JM, Zheng XZ, Chen JG
Archives of oral biology 2023 Mar;147:105625
Archives of oral biology 2023 Mar;147:105625
NONHSAT021545/miR-330-3p/EREG: A Cooperative Axis in Breast Cancer Prognosis and Treatment.
Zhang Y, Guo C, Yang S, Elkharti M, Liu R, Sun MZ, Liu S
Journal of clinical medicine 2023 Mar 24;12(7)
Journal of clinical medicine 2023 Mar 24;12(7)
EGR1 induces EMT in pancreatic cancer via a P300/SNAI2 pathway.
Wang Y, Qin C, Zhao B, Li Z, Li T, Yang X, Zhao Y, Wang W
Journal of translational medicine 2023 Mar 17;21(1):201
Journal of translational medicine 2023 Mar 17;21(1):201
Inhibition of IDH3α Enhanced the Efficacy of Chemoimmunotherapy by Regulating Acidic Tumor Microenvironments.
Zhang L, Song Y, Dai X, Xu W, Li M, Zhu Y
Cancers 2023 Mar 16;15(6)
Cancers 2023 Mar 16;15(6)
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
Chen H, Yang W, Li Y, Ji Z
Cell death & disease 2023 Jul 15;14(7):433
Cell death & disease 2023 Jul 15;14(7):433
UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.
Hong X, Ma N, Li D, Zhang M, Dong W, Huang J, Ci X, Zhang S
Cell death & disease 2023 Feb 10;14(2):100
Cell death & disease 2023 Feb 10;14(2):100
Downregulation of CYRI-B promotes migration, invasion and EMT by activating the Rac1-STAT3 pathway in gastric cancer.
Liu G, Xia Y, Wang H, Jin X, Chen S, Chen W, Zhang C, He Y
Experimental cell research 2023 Feb 1;423(1):113453
Experimental cell research 2023 Feb 1;423(1):113453
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
Cui L, Lu Y, Zheng J, Guo B, Zhao X
Journal of experimental & clinical cancer research : CR 2023 Dec 7;42(1):335
Journal of experimental & clinical cancer research : CR 2023 Dec 7;42(1):335
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells.
Chen Y, He Z, Yang S, Chen C, Xiong W, He Y, Liu S
Journal of translational medicine 2023 Dec 6;21(1):886
Journal of translational medicine 2023 Dec 6;21(1):886
Histone demethylase KDM4B accelerates the progression of glioblastoma via the epigenetic regulation of MYC stability.
Wang Z, Cai H, Li Z, Sun W, Zhao E, Cui H
Clinical epigenetics 2023 Dec 13;15(1):192
Clinical epigenetics 2023 Dec 13;15(1):192
Combined effects of vitamin D and neferine on the progression and metastasis of colorectal cancer.
Yang J, Zhang Q, Huang G, Cong J, Wang T, Zhai X, Zhang J, Qi G, Zhou L, Jin J
Journal of cancer research and clinical oncology 2023 Aug;149(9):6203-6210
Journal of cancer research and clinical oncology 2023 Aug;149(9):6203-6210
PRSS2 regulates EMT and metastasis via MMP-9 in gastric cancer.
Wang F, Yi J, Chen Y, Bai X, Lu C, Feng S, Zhou X
Acta histochemica 2023 Aug;125(6):152071
Acta histochemica 2023 Aug;125(6):152071
Comprehensive bioinformatics and experimental analysis of SH3PXD2B reveals its carcinogenic effect in gastric carcinoma.
Zhu Y, Hu Y, Wang P, Dai X, Fu Y, Xia Y, Sun L, Ruan S
Life sciences 2023 Aug 1;326:121792
Life sciences 2023 Aug 1;326:121792
ZSWIM1 Promotes the Proliferation and Metastasis of Lung Adenocarcinoma Cells through the STK38/MEKK2/ERK1/2 Axis.
Gao X, Lian Q, Guan B, Liu QY, Meng M, Chen Y, Jin J, Li H, Liu X, Sun Z, Liu L, He QY, Zhang G
Journal of proteome research 2023 Apr 7;22(4):1080-1091
Journal of proteome research 2023 Apr 7;22(4):1080-1091
Multifunctional Drug-Loaded Phase-Change Nanoparticles Inhibit the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma by Affecting the Activity of Activated Hepatic Stellate Cells.
Zou X, Li T, Mao Y, Zhu M, Chen X, Niu J, Dong T, Jiang J, Yang X
BioMed research international 2022;2022:6441179
BioMed research international 2022;2022:6441179
CD44v6+ Hepatocellular Carcinoma Cells Maintain Stemness Properties through Met/cJun/Nanog Signaling.
Chen W, Wang R, Zhao Y, Li Y, Wang X, Peng W, Bai S, Zheng M, Liu M, Cheng B
Stem cells international 2022;2022:5853707
Stem cells international 2022;2022:5853707
Smurf2 suppresses the metastasis of hepatocellular carcinoma via ubiquitin degradation of Smad2.
Song D, Li S, Ning L, Zhang S, Cai Y
Open medicine (Warsaw, Poland) 2022;17(1):384-396
Open medicine (Warsaw, Poland) 2022;17(1):384-396
The homeostatic malfunction of a novel feedback pathway formed by lncRNA021545, miR-330-3p and epiregulin contributes in hepatocarcinoma progression via mediating epithelial-mesenchymal transition.
Yang S, Zhang Y, Guo C, Liu R, Elkharti M, Ge Z, Liu Q, Liu S, Sun MZ
American journal of cancer research 2022;12(6):2492-2525
American journal of cancer research 2022;12(6):2492-2525
Interleukin-17 promotes the development of ovarian cancer through upregulation of MTA1 expression.
Guo N, Zhang J
American journal of cancer research 2022;12(12):5646-5656
American journal of cancer research 2022;12(12):5646-5656
Neutrophils Promote Tumor Progression in Oral Squamous Cell Carcinoma by Regulating EMT and JAK2/STAT3 Signaling Through Chemerin.
Hu X, Xiang F, Feng Y, Gao F, Ge S, Wang C, Zhang X, Wang N
Frontiers in oncology 2022;12:812044
Frontiers in oncology 2022;12:812044
IQGAP3 in clear cell renal cell carcinoma contributes to drug resistance and genome stability.
Li W, Wang Z, Wang H, Zhang J, Wang X, Xing S, Chen S
PeerJ 2022;10:e14201
PeerJ 2022;10:e14201
ATP11A promotes EMT by regulating Numb PRR(L) in pancreatic cancer cells.
Chen L, Tang J, Sheng W, Sun J, Ma Y, Dong M
PeerJ 2022;10:e13172
PeerJ 2022;10:e13172
An epithelial-mesenchymal plasticity signature identifies two novel LncRNAs with the opposite regulation.
Kumar P, Khadirnaikar S, Bhandari N, Chatterjee A, Shukla S
Frontiers in cell and developmental biology 2022;10:885785
Frontiers in cell and developmental biology 2022;10:885785
Targeting MALT1 Suppresses the Malignant Progression of Colorectal Cancer via miR-375/miR-365a-3p/NF-κB Axis.
Qian R, Niu X, Wang Y, Guo Z, Deng X, Ding Z, Zhou M, Deng H
Frontiers in cell and developmental biology 2022;10:845048
Frontiers in cell and developmental biology 2022;10:845048
Exosomal miR-22-3p from Mesenchymal Stem Cells Inhibits the Epithelial-Mesenchymal Transition (EMT) of Melanoma Cells by Regulating LGALS1.
Chen Y, Fang Y, Li L, Luo H, Cao T, Tu B
Frontiers in bioscience (Landmark edition) 2022 Sep 29;27(9):275
Frontiers in bioscience (Landmark edition) 2022 Sep 29;27(9):275
3-Nitrobenzanthrone promotes malignant transformation in human lung epithelial cells through the epiregulin-signaling pathway.
Chen KY, Tseng CH, Feng PH, Sun WL, Ho SC, Lin CW, Van Hiep N, Luo CS, Tseng YH, Chen TT, Liu WT, Lee KY, Wu SM
Cell biology and toxicology 2022 Oct;38(5):865-887
Cell biology and toxicology 2022 Oct;38(5):865-887
ALG3 Promotes Peritoneal Metastasis of Ovarian Cancer through Increasing Interaction of α1,3-mannosylated uPAR and ADAM8.
Cui X, Pei X, Wang H, Feng P, Qin H, Liu S, Yan Q, Liu J
Cells 2022 Oct 6;11(19)
Cells 2022 Oct 6;11(19)
Cerulenin suppresses ErbB2-overexpressing breast cancer by targeting ErbB2/PKM2 pathway.
Lv S, Zhang Y, Song J, Chen J, Huang B, Luo Y, Zhao Y
Medical oncology (Northwood, London, England) 2022 Oct 29;40(1):5
Medical oncology (Northwood, London, England) 2022 Oct 29;40(1):5
CHRNB2 represses pancreatic cancer migration and invasion via inhibiting β-catenin pathway.
Qin C, Li T, Wang Y, Zhao B, Li Z, Li T, Yang X, Zhao Y, Wang W
Cancer cell international 2022 Nov 7;22(1):340
Cancer cell international 2022 Nov 7;22(1):340
Circular RNA hsa_circ_0051040 Promotes Hepatocellular Carcinoma Progression by Sponging miR-569 and Regulating ITGAV Expression.
Ju L, Yao M, Lu R, Cao Y, Wang H, Yuan L, Xiao F, Shao J, Cai W, Chen L, Bian Z
Cells 2022 Nov 11;11(22)
Cells 2022 Nov 11;11(22)
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Li T, Zhai D, Zhang M, Ye R, Kuang X, Shao N, Bi J, Lin Y
Cancer letters 2022 Nov 1;548:215904
Cancer letters 2022 Nov 1;548:215904
Downregulation of estrogen receptor-α36 expression attenuates metastasis of hepatocellular carcinoma cells.
Wang R, Chen J, Yu H, Wei Z, Ma M, Ye X, Wu W, Chen H, Fu Z
Environmental toxicology 2022 May;37(5):1113-1123
Environmental toxicology 2022 May;37(5):1113-1123
miR-217-5p suppresses epithelial-mesenchymal transition and the NF-κB signaling pathway in breast cancer via targeting of metadherin.
Yang L, Liu S, Yang L, Xu B, Wang M, Kong X, Song Z
Oncology letters 2022 May;23(5):162
Oncology letters 2022 May;23(5):162
Exosomal MMP-1 transfers metastasis potential in triple-negative breast cancer through PAR1-mediated EMT.
Zhu Y, Tao Z, Chen Y, Lin S, Zhu M, Ji W, Liu X, Li T, Hu X
Breast cancer research and treatment 2022 May;193(1):65-81
Breast cancer research and treatment 2022 May;193(1):65-81
The miR-214-3p/c-Ski axis modulates endothelial-mesenchymal transition in human coronary artery endothelial cells in vitro and in mice model in vivo.
Wang J, Li H, Lv Z, Luo X, Deng W, Zou T, Zhang Y, Sang W, Wang X
Human cell 2022 Mar;35(2):486-497
Human cell 2022 Mar;35(2):486-497
Inhibition of translocator protein 18 kDa suppressed the progression of glioma via the ELAV-like RNA-binding protein 1/MAPK-activated protein kinase 3 axis.
Wang J, Ren P, Zeng Z, Ma L, Li Y, Zhang H, Guo W
Bioengineered 2022 Mar;13(3):7457-7470
Bioengineered 2022 Mar;13(3):7457-7470
Chelerythrine inhibits the progression of glioblastoma by suppressing the TGFB1-ERK1/2/Smad2/3-Snail/ZEB1 signaling pathway.
Zhu M, Niu J, Jiang J, Dong T, Chen Y, Yang X, Liu P
Life sciences 2022 Mar 15;293:120358
Life sciences 2022 Mar 15;293:120358
Crumbs3 is expressed in oral squamous cell carcinomas and promotes cell migration and proliferation by affecting RhoA activity.
Yokoyama Y, Iioka H, Horii A, Kondo E
Oncology letters 2022 Jun;23(6):173
Oncology letters 2022 Jun;23(6):173
LncRNA BACE1-AS promotes the progression of osteosarcoma through miR-762/SOX7 axis.
Wang C, Zhang T, Yang L, Na X, Qu Y
Molecular biology reports 2022 Jul;49(7):5853-5862
Molecular biology reports 2022 Jul;49(7):5853-5862
Overexpression of ERCC6L correlates with poor prognosis and confers malignant phenotypes of lung adenocarcinoma.
Huang X, Jiang L, Lu S, Yuan M, Lin H, Li B, Wen Z, Zhong Y
Oncology reports 2022 Jul;48(1)
Oncology reports 2022 Jul;48(1)
Copper ionophore elesclomol selectively targets GNAQ/11-mutant uveal melanoma.
Li Y, Yang J, Zhang Q, Xu S, Sun W, Ge S, Xu X, Jager MJ, Jia R, Zhang J, Fan X
Oncogene 2022 Jul;41(27):3539-3553
Oncogene 2022 Jul;41(27):3539-3553
ZC3H15 promotes glioblastoma progression through regulating EGFR stability.
Hou J, Xu M, Gu H, Pei D, Liu Y, Huang P, Chang H, Cui H
Cell death & disease 2022 Jan 13;13(1):55
Cell death & disease 2022 Jan 13;13(1):55
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Li M, Rao X, Cui Y, Zhang L, Li X, Wang B, Zheng Y, Teng L, Zhou T, Zhuo W
Oncogene 2022 Feb;41(6):770-781
Oncogene 2022 Feb;41(6):770-781
Numb-PRRL promotes TGF-β1- and EGF-induced epithelial-to-mesenchymal transition in pancreatic cancer.
Sheng W, Tang J, Cao R, Shi X, Ma Y, Dong M
Cell death & disease 2022 Feb 23;13(2):173
Cell death & disease 2022 Feb 23;13(2):173
USF1-CHCHD4 axis promotes lung adenocarcinoma progression partially via activating the MYC pathway.
Zhou Y, Zhao Y, Ma W, Zhang L, Jiang Y, Dong W
Discover oncology 2022 Dec 8;13(1):136
Discover oncology 2022 Dec 8;13(1):136
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Wu X, Zhang H, Jiang G, Peng M, Li C, Lu J, Jiang S, Yang X, Jiang Y
Clinical and experimental immunology 2022 Dec 31;210(3):309-320
Clinical and experimental immunology 2022 Dec 31;210(3):309-320
A multifunctional black phosphorus-based adhesive patch intrinsically induces partial EMT for effective burn wound healing.
Wang X, Tang X, Li N, Sun Y, Yu R, Zhang J, Li D, Yang B, Sun H
Biomaterials science 2022 Dec 20;11(1):235-247
Biomaterials science 2022 Dec 20;11(1):235-247
LncRNA ELF3-AS1 inhibits gastric cancer by forming a negative feedback loop with SNAI2 and regulates ELF3 mRNA stability via interacting with ILF2/ILF3 complex.
Li D, Shen L, Zhang X, Chen Z, Huang P, Huang C, Qin S
Journal of experimental & clinical cancer research : CR 2022 Dec 2;41(1):332
Journal of experimental & clinical cancer research : CR 2022 Dec 2;41(1):332
SEC14L3 plays a tumor-suppressive role in breast cancer through a Wnt/β-catenin-related way.
Zhu Q, Wan NB, Deng HW, Lu LL, Zhang Y, He X, Liu H, He Y
Experimental cell research 2022 Aug 1;417(1):113161
Experimental cell research 2022 Aug 1;417(1):113161
Bolbostemma paniculatum (Maxim.) Franquet extract suppresses the development of colorectal cancer through downregulation of PI3K/Akt pathway.
Li Y, Sun Y, Zhang Q, Liu Y, Niu Y, Li X, Cai D
Journal of ethnopharmacology 2022 Apr 6;287:114937
Journal of ethnopharmacology 2022 Apr 6;287:114937
Mitochondrial calcium uptake regulates tumour progression in embryonal rhabdomyosarcoma.
Chiu HY, Loh AHP, Taneja R
Cell death & disease 2022 Apr 30;13(4):419
Cell death & disease 2022 Apr 30;13(4):419
Epigenetic Deregulation of Protein Tyrosine Kinase 6 Promotes Carcinogenesis of Oral Squamous Cell Carcinoma.
Hsieh YP, Chen KC, Chen MY, Huang LY, Su AY, Chiang WF, Huang WT, Huang TT
International journal of molecular sciences 2022 Apr 19;23(9)
International journal of molecular sciences 2022 Apr 19;23(9)
Polydatin Inhibits Cell Viability, Migration, and Invasion Through Suppressing the c-Myc Expression in Human Cervical Cancer.
Bai L, Ma Y, Wang X, Feng Q, Zhang Z, Wang S, Zhang H, Lu X, Xu Y, Zhao E, Cui H
Frontiers in cell and developmental biology 2021;9:587218
Frontiers in cell and developmental biology 2021;9:587218
MRPL13 Promotes Tumor Cell Proliferation, Migration and EMT Process in Breast Cancer Through the PI3K-AKT-mTOR Pathway.
Cai M, Li H, Chen R, Zhou X
Cancer management and research 2021;13:2009-2024
Cancer management and research 2021;13:2009-2024
JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation.
Zhang B, Zhang Y, Jiang X, Su H, Wang Q, Wudu M, Jiang J, Ren H, Xu Y, Liu Z, Qiu X
Journal of Cancer 2021;12(4):976-987
Journal of Cancer 2021;12(4):976-987
Linc01513 inhibits the malignant potential of Nasopharyngeal carcinoma by binding to PTBP1.
Wang J, Cai X, Zhang L, Lei D
Journal of Cancer 2021;12(24):7380-7389
Journal of Cancer 2021;12(24):7380-7389
Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development.
Guo S, Meng L, Liu H, Yuan L, Zhao N, Ni J, Zhang Y, Ben J, Li YP, Ma J
Theranostics 2021;11(9):4316-4334
Theranostics 2021;11(9):4316-4334
TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.
Li R, Zhu L, Peng Y, Zhang X, Dai C, Liu D
Frontiers in oncology 2021;11:695740
Frontiers in oncology 2021;11:695740
MIER3 induces epithelial-mesenchymal transition and promotes breast cancer cell aggressiveness via forming a co-repressor complex with HDAC1/HDAC2/Snail.
Huang W, Chen J, Liu X, Liu X, Duan S, Chen L, Liu X, Lan J, Zou Y, Guo D, Zhou J
Experimental cell research 2021 Sep 1;406(1):112722
Experimental cell research 2021 Sep 1;406(1):112722
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
Guo K, Wang P, Zhang L, Zhou Y, Dai X, Yan Y, Chen Y, Wasan HS, Yu J, Ruan S, Sun L
Cancer science 2021 Oct;112(10):4176-4186
Cancer science 2021 Oct;112(10):4176-4186
NOTCH2NLA silencing inhibits ovarian carcinoma progression and oncogenic activity in vivo and in vitro.
Guo W, Sun Z, Zhao N, Zhou Y, Ren J, Huang L, Ping Y
Annals of translational medicine 2021 Nov;9(22):1669
Annals of translational medicine 2021 Nov;9(22):1669
The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.
Chen YD, Cai FY, Mao YZ, Yang YS, Xu K, Liu XF, Fan WW, Chen W, Jiang FQ, Zhang H
Chinese journal of natural medicines 2021 Nov;19(11):815-824
Chinese journal of natural medicines 2021 Nov;19(11):815-824
Effects of Cynaroside on Cell Proliferation, Apoptosis, Migration and Invasion though the MET/AKT/mTOR Axis in Gastric Cancer.
Ji J, Wang Z, Sun W, Li Z, Cai H, Zhao E, Cui H
International journal of molecular sciences 2021 Nov 9;22(22)
International journal of molecular sciences 2021 Nov 9;22(22)
Inhibition of DEC2 is necessary for exiting cell dormancy in salivary adenoid cystic carcinoma.
Yang X, Wu JS, Li M, Zhang WL, Gao XL, Wang HF, Yu XH, Pang X, Zhang M, Liang XH, Tang YL
Journal of experimental & clinical cancer research : CR 2021 May 14;40(1):169
Journal of experimental & clinical cancer research : CR 2021 May 14;40(1):169
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
Li P, Cao S, Huang Y, Zhang Y, Liu J, Cai X, Zhou L, Li J, Jiang Z, Ding L, Zheng Z, Li S, Ye Q
Cell death discovery 2021 Jul 29;7(1):198
Cell death discovery 2021 Jul 29;7(1):198
Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.
Jiang F, Ren S, Chen Y, Zhang A, Zhu Y, Zhang Z, Li Z, Piao D
Oncology reports 2021 Jan;45(1):139-150
Oncology reports 2021 Jan;45(1):139-150
Overexpression of NCAPG inhibits cardia adenocarcinoma apoptosis and promotes epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway.
Zhang X, Zhu M, Wang H, Song Z, Zhan D, Cao W, Han Y, Jia J
Gene 2021 Jan 15;766:145163
Gene 2021 Jan 15;766:145163
Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/β-catenin/PPARδ signalling.
Wang Y, Lan W, Xu M, Song J, Mao J, Li C, Du X, Jiang Y, Li E, Zhang R, Wang Q
Cell death & disease 2021 Feb 26;12(2):214
Cell death & disease 2021 Feb 26;12(2):214
Inhibitory role of ATF3 in gastric cancer progression through regulating cell EMT and stemness.
Huang C, Chen R, Zheng F, Tang Y, Wang X, Chen Z, Lai X
Cancer cell international 2021 Feb 19;21(1):127
Cancer cell international 2021 Feb 19;21(1):127
FOXD1 promotes EMT and cell stemness of oral squamous cell carcinoma by transcriptional activation of SNAI2.
Chen Y, Liang W, Liu K, Shang Z
Cell & bioscience 2021 Aug 4;11(1):154
Cell & bioscience 2021 Aug 4;11(1):154
Neuron specific enolase promotes tumor metastasis by activating the Wnt/β-catenin pathway in small cell lung cancer.
Zha Z, Li D, Zhang P, Wang P, Fang X, Liu X, Weng C, Li B, Wu Y, Mao H, Wang L, Xu L, Dong J, Guan M, Lu L, Liu G
Translational oncology 2021 Apr;14(4):101039
Translational oncology 2021 Apr;14(4):101039
Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer.
Gudi RR, Janakiraman H, Howe PH, Palanisamy V, Vasu C
Oncotarget 2021 Apr 13;12(8):807-822
Oncotarget 2021 Apr 13;12(8):807-822
Fibroblast Activation Protein (FAP) Overexpression Induces Epithelial-Mesenchymal Transition (EMT) in Oral Squamous Cell Carcinoma by Down-Regulating Dipeptidyl Peptidase 9 (DPP9).
Wu QQ, Zhao M, Huang GZ, Zheng ZN, Chen Y, Zeng WS, Lv XZ
OncoTargets and therapy 2020;13:2599-2611
OncoTargets and therapy 2020;13:2599-2611
Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells.
Yang B, Bai H, Sa Y, Zhu P, Liu P
Journal of Cancer 2020;11(8):2303-2317
Journal of Cancer 2020;11(8):2303-2317
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.
Chen Y, Niu J, Li L, Li Z, Jiang J, Zhu M, Dong T, Zhang J, Shi C, Xu P, Lu Y, Jiang Y, Liu P, Chen W
Life sciences 2020 Oct 1;258:118158
Life sciences 2020 Oct 1;258:118158
IMPDH1/YB-1 Positive Feedback Loop Assembles Cytoophidia and Represents a Therapeutic Target in Metastatic Tumors.
Ruan H, Song Z, Cao Q, Ni D, Xu T, Wang K, Bao L, Tong J, Xiao H, Xiao W, Cheng G, Xiong Z, Liang H, Liu D, Wang L, Olivier T, Jane BH, Yang H, Zhang X, Chen K
Molecular therapy : the journal of the American Society of Gene Therapy 2020 May 6;28(5):1299-1313
Molecular therapy : the journal of the American Society of Gene Therapy 2020 May 6;28(5):1299-1313
IGF-1 promotes multiple myeloma progression through PI3K/Akt-mediated epithelial-mesenchymal transition.
Peng Y, Li F, Zhang P, Wang X, Shen Y, Feng Y, Jia Y, Zhang R, Hu J, He A
Life sciences 2020 May 15;249:117503
Life sciences 2020 May 15;249:117503
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
Zhang J, Chen Y, Lin J, Jia R, An T, Dong T, Zhang Y, Yang X
DNA and cell biology 2020 Mar;39(3):355-367
DNA and cell biology 2020 Mar;39(3):355-367
(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.
Wang YS, Li H, Li Y, Zhang S, Jin YH
Biomolecules 2020 Mar 31;10(4)
Biomolecules 2020 Mar 31;10(4)
SP1-activated long noncoding RNA lncRNA GCMA functions as a competing endogenous RNA to promote tumor metastasis by sponging miR-124 and miR-34a in gastric cancer.
Tian Y, Ma R, Sun Y, Liu H, Zhang H, Sun Y, Liu L, Li Y, Song L, Gao P
Oncogene 2020 Jun;39(25):4854-4868
Oncogene 2020 Jun;39(25):4854-4868
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
Jiang F, Chen Y, Ren S, Li Z, Sun K, Xing Y, Zhu Y, Piao D
International journal of oncology 2020 Jul;57(1):183-196
International journal of oncology 2020 Jul;57(1):183-196
Long noncoding RNA MAPKAPK5-AS1 promotes colorectal cancer progression by cis-regulating the nearby gene MK5 and acting as a let-7f-1-3p sponge.
Yang T, Chen WC, Shi PC, Liu MR, Jiang T, Song H, Wang JQ, Fan RZ, Pei DS, Song J
Journal of experimental & clinical cancer research : CR 2020 Jul 20;39(1):139
Journal of experimental & clinical cancer research : CR 2020 Jul 20;39(1):139
CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling.
Zhong Q, Fang Y, Lai Q, Wang S, He C, Li A, Liu S, Yan Q
Journal of experimental & clinical cancer research : CR 2020 Jul 11;39(1):132
Journal of experimental & clinical cancer research : CR 2020 Jul 11;39(1):132
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Ma J, Qi J, Li S, Zhang C, Wang H, Shao L, Yuan X, Sha Q
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Graphene Oxide Promotes Cancer Metastasis through Associating with Plasma Membrane To Promote TGF-β Signaling-Dependent Epithelial-Mesenchymal Transition.
Zhu J, Li B, Xu M, Liu R, Xia T, Zhang Z, Xu Y, Liu S
ACS nano 2020 Jan 28;14(1):818-827
ACS nano 2020 Jan 28;14(1):818-827
Aberrant methylation‑mediated decrease of lncRNA HNF1A‑AS1 contributes to malignant progression of laryngeal squamous cell carcinoma via EMT.
Shi Y, Zhang Q, Xie M, Feng Y, Ma S, Yi C, Wang Z, Li Y, Liu X, Liu H, Yang H, Yan Y, Zhang Y, Ren X, Luo H
Oncology reports 2020 Dec;44(6):2503-2516
Oncology reports 2020 Dec;44(6):2503-2516
Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.
Guo Y, Fan Y, Pei X
Cancer medicine 2020 Apr;9(7):2564-2578
Cancer medicine 2020 Apr;9(7):2564-2578
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Chen Y, Liu P, Sun P, Jiang J, Zhu Y, Dong T, Cui Y, Tian Y, An T, Zhang J, Li Z, Yang X
Theranostics 2019;9(5):1453-1473
Theranostics 2019;9(5):1453-1473
Nr5a2 promotes tumor growth and metastasis of gastric cancer AGS cells by Wnt/beta-catenin signaling.
Liu L, Li Y, Pan B, Zhang T, Wei D, Zhu Y, Guo Y
OncoTargets and therapy 2019;12:2891-2902
OncoTargets and therapy 2019;12:2891-2902
Lipase member H is a downstream molecular target of hypoxia inducible factor-1α and promotes papillary thyroid carcinoma cell migration in BCPAP and KTC-1 cell lines.
Li Y, Zhou X, Zhang Q, Chen E, Sun Y, Ye D, Wang O, Zhang X, Lyu J
Cancer management and research 2019;11:931-941
Cancer management and research 2019;11:931-941
CD36 promotes the epithelial-mesenchymal transition and metastasis in cervical cancer by interacting with TGF-β.
Deng M, Cai X, Long L, Xie L, Ma H, Zhou Y, Liu S, Zeng C
Journal of translational medicine 2019 Oct 26;17(1):352
Journal of translational medicine 2019 Oct 26;17(1):352
α-Aminoisobutyric Acid-Containing Amphipathic Helical Peptide-Cyclic RGD Conjugation as a Potential Drug Delivery System for MicroRNA Replacement Therapy in Vitro.
Taniguchi K, Wada SI, Ito Y, Hayashi J, Inomata Y, Lee SW, Tanaka T, Komura K, Akao Y, Urata H, Uchiyama K
Molecular pharmaceutics 2019 Nov 4;16(11):4542-4550
Molecular pharmaceutics 2019 Nov 4;16(11):4542-4550
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Wu W, He K, Guo Q, Chen J, Zhang M, Huang K, Yang D, Wu L, Deng Y, Luo X, Yu H, Ding Q, Xiang G
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
M2 macrophages promote NSCLC metastasis by upregulating CRYAB.
Guo Z, Song J, Hao J, Zhao H, Du X, Li E, Kuang Y, Yang F, Wang W, Deng J, Wang Q
Cell death & disease 2019 May 16;10(6):377
Cell death & disease 2019 May 16;10(6):377
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
Li Z, Chen Y, An T, Liu P, Zhu J, Yang H, Zhang W, Dong T, Jiang J, Zhang Y, Jiang M, Yang X
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
Xie K, Xu C, Zhang M, Wang M, Min L, Qian C, Wang Q, Ni Z, Mou S, Dai H, Pang H, Gu L
Cell death & disease 2019 Dec 4;10(12):915
Cell death & disease 2019 Dec 4;10(12):915
Prognostic value of multiple epithelial mesenchymal transition-associated proteins in intrahepatic cholangiocarcinoma.
Tian X, Cao Z, Ding Q, Li Z, Zhang C
Oncology letters 2019 Aug;18(2):2059-2065
Oncology letters 2019 Aug;18(2):2059-2065
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Liu Q, Guan Y, Li Z, Wang Y, Liu Y, Cui R, Wang Y
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
Cisatracurium Retards Cell Migration and Invasion Upon Upregulation of p53 and Inhibits the Aggressiveness of Colorectal Cancer.
Yabasin IB, Sanches JGP, Ibrahim MM, Huidan J, Williams W, Lu ZL, Wen Q
Frontiers in physiology 2018;9:941
Frontiers in physiology 2018;9:941
LncRNA UCA1 is necessary for TGF-β-induced epithelial-mesenchymal transition and stemness via acting as a ceRNA for Slug in glioma cells.
Li Z, Liu H, Zhong Q, Wu J, Tang Z
FEBS open bio 2018 Nov;8(11):1855-1865
FEBS open bio 2018 Nov;8(11):1855-1865
The PLGF/c-MYC/miR-19a axis promotes metastasis and stemness in gallbladder cancer.
Li H, Jin Y, Hu Y, Jiang L, Liu F, Zhang Y, Hao Y, Chen S, Wu X, Liu Y
Cancer science 2018 May;109(5):1532-1544
Cancer science 2018 May;109(5):1532-1544
The long non-coding RNA PTTG3P promotes cell growth and metastasis via up-regulating PTTG1 and activating PI3K/AKT signaling in hepatocellular carcinoma.
Huang JL, Cao SW, Ou QS, Yang B, Zheng SH, Tang J, Chen J, Hu YW, Zheng L, Wang Q
Molecular cancer 2018 May 26;17(1):93
Molecular cancer 2018 May 26;17(1):93
Systematic analyses reveal long non-coding RNA (PTAF)-mediated promotion of EMT and invasion-metastasis in serous ovarian cancer.
Liang H, Zhao X, Wang C, Sun J, Chen Y, Wang G, Fang L, Yang R, Yu M, Gu Y, Shan H
Molecular cancer 2018 Jun 21;17(1):96
Molecular cancer 2018 Jun 21;17(1):96
ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway.
Wang J, Zhang Z, Li R, Mao F, Sun W, Chen J, Zhang H, Bartsch JW, Shu K, Lei T
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:1066-1077
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:1066-1077
Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis.
Wu J, Xing C, Zhang L, Mao H, Chen X, Liang M, Wang F, Ren H, Cui H, Jiang A, Wang Z, Zou M, Ji Y
Journal of cellular and molecular medicine 2018 Feb;22(2):1190-1201
Journal of cellular and molecular medicine 2018 Feb;22(2):1190-1201
UNC0638, a G9a inhibitor, suppresses epithelial‑mesenchymal transition‑mediated cellular migration and invasion in triple negative breast cancer.
Liu XR, Zhou LH, Hu JX, Liu LM, Wan HP, Zhang XQ
Molecular medicine reports 2018 Feb;17(2):2239-2244
Molecular medicine reports 2018 Feb;17(2):2239-2244
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
Zhao B, Liu L, Mao J, Zhang Z, Wang Q, Li Q
Cell death & disease 2018 Feb 22;9(3):307
Cell death & disease 2018 Feb 22;9(3):307
Long noncoding RNA NEAT1, regulated by LIN28B, promotes cell proliferation and migration through sponging miR-506 in high-grade serous ovarian cancer.
Yong W, Yu D, Jun Z, Yachen D, Weiwei W, Midie X, Xingzhu J, Xiaohua W
Cell death & disease 2018 Aug 28;9(9):861
Cell death & disease 2018 Aug 28;9(9):861
SphK1 modulates cell migration and EMT-related marker expression by regulating the expression of p-FAK in colorectal cancer cells.
Xu CY, Liu SQ, Qin MB, Zhuge CF, Qin L, Qin N, Lai MY, Huang JA
International journal of molecular medicine 2017 May;39(5):1277-1284
International journal of molecular medicine 2017 May;39(5):1277-1284
Correlations between TBL1XR1 and recurrence of colorectal cancer.
Liu H, Xu Y, Zhang Q, Li K, Wang D, Li S, Ning S, Yang H, Shi W, Liu Z, Chen Y
Scientific reports 2017 Mar 15;7:44275
Scientific reports 2017 Mar 15;7:44275
Integrin β4 promotes cell invasion and epithelial-mesenchymal transition through the modulation of Slug expression in hepatocellular carcinoma.
Li XL, Liu L, Li DD, He YP, Guo LH, Sun LP, Liu LN, Xu HX, Zhang XP
Scientific reports 2017 Jan 13;7:40464
Scientific reports 2017 Jan 13;7:40464
Activation of anaphase-promoting complex by p53 induces a state of dormancy in cancer cells against chemotherapeutic stress.
Dai Y, Wang L, Tang J, Cao P, Luo Z, Sun J, Kiflu A, Sai B, Zhang M, Wang F, Li G, Xiang J
Oncotarget 2016 May 3;7(18):25478-92
Oncotarget 2016 May 3;7(18):25478-92
PFN2, a novel marker of unfavorable prognosis, is a potential therapeutic target involved in esophageal squamous cell carcinoma.
Cui XB, Zhang SM, Xu YX, Dang HW, Liu CX, Wang LH, Yang L, Hu JM, Liang WH, Jiang JF, Li N, Li Y, Chen YZ, Li F
Journal of translational medicine 2016 May 17;14(1):137
Journal of translational medicine 2016 May 17;14(1):137
Significance of the NOR1-FOXA1/HDAC2-Slug regulatory network in epithelial-mesenchymal transition of tumor cells.
Wang W, Yi M, Chen S, Li J, Li G, Yang J, Zheng P, Zhang H, Xiong W, McCarthy JB, Li G, Li X, Xiang B
Oncotarget 2016 Mar 29;7(13):16745-59
Oncotarget 2016 Mar 29;7(13):16745-59
AEG-1/MTDH-activated autophagy enhances human malignant glioma susceptibility to TGF-β1-triggered epithelial-mesenchymal transition.
Zou M, Zhu W, Wang L, Shi L, Gao R, Ou Y, Chen X, Wang Z, Jiang A, Liu K, Xiao M, Ni P, Wu D, He W, Sun G, Li P, Zhai S, Wang X, Hu G
Oncotarget 2016 Mar 15;7(11):13122-38
Oncotarget 2016 Mar 15;7(11):13122-38
Conditional ablation of TGF-β signaling inhibits tumor progression and invasion in an induced mouse bladder cancer model.
Liang Y, Zhu F, Zhang H, Chen D, Zhang X, Gao Q, Li Y
Scientific reports 2016 Jul 5;6:29479
Scientific reports 2016 Jul 5;6:29479
Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent ERK signaling.
Liu H, Zhang Q, Li K, Gong Z, Liu Z, Xu Y, Swaney MH, Xiao K, Chen Y
Oncotarget 2016 Dec 6;7(49):81223-81240
Oncotarget 2016 Dec 6;7(49):81223-81240
STK33 plays an important positive role in the development of human large cell lung cancers with variable metastatic potential.
Wang P, Cheng H, Wu J, Yan A, Zhang L
Acta biochimica et biophysica Sinica 2015 Mar;47(3):214-23
Acta biochimica et biophysica Sinica 2015 Mar;47(3):214-23
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 12129-1-AP(SNAI2 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SNAI2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SNAI2. This antibody recognizes human,mouse,rat antigen. The SNAI2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.